In the current study, thermoplasmonic characteristics of Astatine nanoparticles with spherical, core-shell and rod shapes are investigated. In order to investigate these characteristics, interaction of synchrotron radiation emission as a function of the beam energy and Astatine nanoparticles were simulated using 3D finite element method. Firstly, absorption and extinction cross sections were calculated. Then, increases in temperature due to synchrotron radiation emission as a function of the beam energy absorption were calculated in Astatine nanoparticles by solving heat equation. The obtained results show that Astatine nanorods are more appropriate option for using in optothermal human cancer cells, tissues and tumors treatment method.
{"title":"Research activities on novel drug delivery systems of astatine nanoparticles in human gum cancer cells, tissues and tumors treatment under synchrotron radiation","authors":"A. Heidari, K. Schmitt, M. Henderson, E. Besana","doi":"10.15761/DOMR.1000345","DOIUrl":"https://doi.org/10.15761/DOMR.1000345","url":null,"abstract":"In the current study, thermoplasmonic characteristics of Astatine nanoparticles with spherical, core-shell and rod shapes are investigated. In order to investigate these characteristics, interaction of synchrotron radiation emission as a function of the beam energy and Astatine nanoparticles were simulated using 3D finite element method. Firstly, absorption and extinction cross sections were calculated. Then, increases in temperature due to synchrotron radiation emission as a function of the beam energy absorption were calculated in Astatine nanoparticles by solving heat equation. The obtained results show that Astatine nanorods are more appropriate option for using in optothermal human cancer cells, tissues and tumors treatment method.","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75001171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Takayama, A. Moroi, K. Uno, Yuki Saito, K. Yoshizawa, K. Ueki
This study investigated the relationship between total short-pulse CO 2 laser irradiation intensity and bone regeneration in rabbit nasal bone. Forty-eight rabbits (12- 16 weeks: 2.5-3.0 kg) were used in this study. After the cranial bone was exposed under general anesthesia, CO 2 laser irradiation was applied directly to the nasal bone under various conditions. Laser irradiation pulses with a spike pulse width of 360 ns, a pulse tail length of 92.6 ms, and an irradiation intensity per pulse of 650 mJ/ cm 2 were applied in a multipulse mode at a frequency of 50 Hz. The rabbits were divided into four groups of six, in which a energy density of 88 J/cm 2 (Group A), 220 J/cm 2 (Group B), 441 J/cm 2 (Group C), or 661 J/cm 2 (Group D) was applied. The rabbits were sacrificed 8 and 16 weeks after the procedure, and tissue sections were assessed histologically. Bone regeneration in the maxillary sinus was observed in groups A, B, and C at 8 and 16 weeks, but not in group D. The surface area ratio of new bone was significantly higher in group A. 88 J/cm 2 was the most effective energy density for bone regeneration.
{"title":"Bone regeneration in rabbit nasal bone by laser pulse shape control CO2 laser","authors":"A. Takayama, A. Moroi, K. Uno, Yuki Saito, K. Yoshizawa, K. Ueki","doi":"10.15761/DOMR.1000355","DOIUrl":"https://doi.org/10.15761/DOMR.1000355","url":null,"abstract":"This study investigated the relationship between total short-pulse CO 2 laser irradiation intensity and bone regeneration in rabbit nasal bone. Forty-eight rabbits (12- 16 weeks: 2.5-3.0 kg) were used in this study. After the cranial bone was exposed under general anesthesia, CO 2 laser irradiation was applied directly to the nasal bone under various conditions. Laser irradiation pulses with a spike pulse width of 360 ns, a pulse tail length of 92.6 ms, and an irradiation intensity per pulse of 650 mJ/ cm 2 were applied in a multipulse mode at a frequency of 50 Hz. The rabbits were divided into four groups of six, in which a energy density of 88 J/cm 2 (Group A), 220 J/cm 2 (Group B), 441 J/cm 2 (Group C), or 661 J/cm 2 (Group D) was applied. The rabbits were sacrificed 8 and 16 weeks after the procedure, and tissue sections were assessed histologically. Bone regeneration in the maxillary sinus was observed in groups A, B, and C at 8 and 16 weeks, but not in group D. The surface area ratio of new bone was significantly higher in group A. 88 J/cm 2 was the most effective energy density for bone regeneration.","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"98 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76106711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neurofibromas are relatively common benign tumors usually originating from peripheral nerves. Multiple neurofibromas are seen as part of von Recklinghausen`s neurofibromatosis. But, solitary neurofibroma is particularly a rarity in the Head and Neck. A 69-year-old woman was referred due to a complaint of swelling in the philtrum of upper lip with no other symptoms. Due to the suspicion of a tumor in the lip, MRI was taken and hemangioma was considered. A diagnosis of solitary neurofibroma was made through a surgical specimen by excisioned intra-orally by general anesthesia, from the lesion by histological examination and immunohistochemistry for the S-100 protein. And 4-year follow-up, she was free of symptoms and signs of recurrence were not detected.
{"title":"A rare solitary neurofibroma of the philtrum of upper lip","authors":"G. Takahashi, H. Matsuyama, K. Nakahashi","doi":"10.15761/DOMR.1000351","DOIUrl":"https://doi.org/10.15761/DOMR.1000351","url":null,"abstract":"Neurofibromas are relatively common benign tumors usually originating from peripheral nerves. Multiple neurofibromas are seen as part of von Recklinghausen`s neurofibromatosis. But, solitary neurofibroma is particularly a rarity in the Head and Neck. A 69-year-old woman was referred due to a complaint of swelling in the philtrum of upper lip with no other symptoms. Due to the suspicion of a tumor in the lip, MRI was taken and hemangioma was considered. A diagnosis of solitary neurofibroma was made through a surgical specimen by excisioned intra-orally by general anesthesia, from the lesion by histological examination and immunohistochemistry for the S-100 protein. And 4-year follow-up, she was free of symptoms and signs of recurrence were not detected.","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"222 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89158075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Gobato, Marcia Regina Risso Gobato, A. Heidari, A. Mitra
The rhodochrosite as crystal oscillator for being an alternative to those of quartz. The rhodochrosite (MnC0 3 ) shows complete solid solution with siderite (FeC0 3 ), and it may contain substantial amounts of Zn, Mg, Co, and Ca. Through an unrestricted Hartree-Fock (UHF) computational simulation, Compact effective potentials (CEP), the infrared spectrum of the protonated rhodochrosite crystal, CH 19 Mn 6 O 8 , and the load distribution by the unit molecule by two widely used methods, Atomic Polar Tensor (APT) and Mulliken, were studied. The rhodochrosite crystal unit cell of structure CMn 6 O 8 , where the load distribution by the molecule was verified in the UHF CEP-4G (Effective core potential (ECP) minimal basis), UHF CEP-31G (ECP split valance) and UHF CEP-121G (ECP triple-split basis). The largest load variation in the APT and Mulliken methods were obtained in the CEP-121G basis set, with δ = 2.922 e δ = 2.650 u.a., respectively, being δ APT > δ Mulliken . The maximum absorbance peaks in the CEP-4G, CEP-31G and CEP-121G basis set are present at the frequencies 2172.23 cm- 1 , with a normalized intensity of 0.65; 2231.4 cm -1 and 0.454; and 2177.24 cm -1 and 1.0, respectively. Later studies could check the advantages and disadvantages of rhodochrosite in the treatment of cancer through synchrotron radiation, such as one oscillator crystal.
菱锰矿作为晶体振荡器是石英的替代品。本文通过不受限制的Hartree-Fock (UHF)计算模拟，研究了质子化红锰矿晶体CH 19 Mn 6 O 8的紧凑有效电位(CEP)、红外光谱以及常用的原子极性张量(APT)和Mulliken方法在单位分子上的负载分布。结构为cmn6 O 8的菱铁矿晶体单元胞，在UHF CEP-4G(有效核心电位(ECP)最小基)、UHF CEP-31G (ECP分裂价)和UHF CEP-121G (ECP三分裂基)下验证了分子的负载分布。在CEP-121G基组中，APT和Mulliken方法的负荷变化最大，δ = 2.922 e δ = 2.650 u.a， δ APT > δ Mulliken。CEP-4G、CEP-31G和CEP-121G基组的最大吸光度峰出现在2172.23 cm- 1频率处，归一化强度为0.65;2231.4 cm -1和0.454;和2177.24 cm -1和1.0。后来的研究可以通过同步辐射检查红锰矿在治疗癌症方面的优缺点，例如一个振荡器晶体。
{"title":"Infrared spectrum, apt charges and mulliken of hartree-fock methods protonated rhodochrosite crystal","authors":"R. Gobato, Marcia Regina Risso Gobato, A. Heidari, A. Mitra","doi":"10.15761/DOMR.1000353","DOIUrl":"https://doi.org/10.15761/DOMR.1000353","url":null,"abstract":"The rhodochrosite as crystal oscillator for being an alternative to those of quartz. The rhodochrosite (MnC0 3 ) shows complete solid solution with siderite (FeC0 3 ), and it may contain substantial amounts of Zn, Mg, Co, and Ca. Through an unrestricted Hartree-Fock (UHF) computational simulation, Compact effective potentials (CEP), the infrared spectrum of the protonated rhodochrosite crystal, CH 19 Mn 6 O 8 , and the load distribution by the unit molecule by two widely used methods, Atomic Polar Tensor (APT) and Mulliken, were studied. The rhodochrosite crystal unit cell of structure CMn 6 O 8 , where the load distribution by the molecule was verified in the UHF CEP-4G (Effective core potential (ECP) minimal basis), UHF CEP-31G (ECP split valance) and UHF CEP-121G (ECP triple-split basis). The largest load variation in the APT and Mulliken methods were obtained in the CEP-121G basis set, with δ = 2.922 e δ = 2.650 u.a., respectively, being δ APT > δ Mulliken . The maximum absorbance peaks in the CEP-4G, CEP-31G and CEP-121G basis set are present at the frequencies 2172.23 cm- 1 , with a normalized intensity of 0.65; 2231.4 cm -1 and 0.454; and 2177.24 cm -1 and 1.0, respectively. Later studies could check the advantages and disadvantages of rhodochrosite in the treatment of cancer through synchrotron radiation, such as one oscillator crystal.","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"67 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75899439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In the current study, thermoplasmonic characteristics of Rutherfordium nanoparticles with spherical, core-shell and rod shapes are investigated. In order to investigate these characteristics, interaction of synchrotron radiation emission as a function of the beam energy and Rutherfordium nanoparticles were simulated using 3D finite element method. Firstly, absorption and extinction cross sections were calculated. Then, increases in temperature due to synchrotron radiation emission as a function of the beam energy absorption were calculated in Rutherfordium nanoparticles by solving heat equation. The obtained results show that Rutherfordium nanorods are more appropriate option for using in optothermal human cancer cells, tissues and tumors treatment method.
{"title":"Abraham-lorentz-dirac force approach to interaction of synchrotron radiation emission as a function of the beam energy and rutherfordium nanoparticles using 3D finite element method (FEM) as an optothermal human cancer cells, tissues and tumors treatment","authors":"A. Heidari, K. Schmitt, M. Henderson, E. Besana","doi":"10.15761/domr.1000338","DOIUrl":"https://doi.org/10.15761/domr.1000338","url":null,"abstract":"In the current study, thermoplasmonic characteristics of Rutherfordium nanoparticles with spherical, core-shell and rod shapes are investigated. In order to investigate these characteristics, interaction of synchrotron radiation emission as a function of the beam energy and Rutherfordium nanoparticles were simulated using 3D finite element method. Firstly, absorption and extinction cross sections were calculated. Then, increases in temperature due to synchrotron radiation emission as a function of the beam energy absorption were calculated in Rutherfordium nanoparticles by solving heat equation. The obtained results show that Rutherfordium nanorods are more appropriate option for using in optothermal human cancer cells, tissues and tumors treatment method.","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73687504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In the current paper, spherical paramagnetic contribution to shielding tensor analysis of nuclear magnetic resonance signals in gum cancer cells, tissues and tumors are investigated. Owing to its high chemical specificity and non–invasive detection capability, in the last decade, spherical paramagnetic contribution to shielding tensor analysis of nuclear magnetic resonance signals in gum cancer cells, tissues and tumors has found wide application in gum cancer screening and diagnosis. In this paper, we describe recent results obtained by applying spherical paramagnetic contribution to shielding tensor analysis of nuclear magnetic resonance signals in gum cancer cells, tissues and tumors to osteosarcoma and chondrosarcoma; the two main bone tumors. The results show the remarkable potential of spherical paramagnetic contribution to shielding tensor analysis of nuclear magnetic resonance signals in gum cancer cells, tissues and tumors to discriminate between subcellular components inside osteo–differentiated osteoblasts and osteosarcoma cells or; at level of tissues; to discriminate chondrogenic tumors giving the possibility to grade the level of malignancy the cartilaginous tumors under investigation.
{"title":"Spherical paramagnetic contribution to shielding tensor analysis of nuclear magnetic resonance signals in gum cancer cells, tissues and tumors","authors":"A. Heidari, R. Gobato","doi":"10.15761/DOMR.1000363","DOIUrl":"https://doi.org/10.15761/DOMR.1000363","url":null,"abstract":"In the current paper, spherical paramagnetic contribution to shielding tensor analysis of nuclear magnetic resonance signals in gum cancer cells, tissues and tumors are investigated. Owing to its high chemical specificity and non–invasive detection capability, in the last decade, spherical paramagnetic contribution to shielding tensor analysis of nuclear magnetic resonance signals in gum cancer cells, tissues and tumors has found wide application in gum cancer screening and diagnosis. In this paper, we describe recent results obtained by applying spherical paramagnetic contribution to shielding tensor analysis of nuclear magnetic resonance signals in gum cancer cells, tissues and tumors to osteosarcoma and chondrosarcoma; the two main bone tumors. The results show the remarkable potential of spherical paramagnetic contribution to shielding tensor analysis of nuclear magnetic resonance signals in gum cancer cells, tissues and tumors to discriminate between subcellular components inside osteo–differentiated osteoblasts and osteosarcoma cells or; at level of tissues; to discriminate chondrogenic tumors giving the possibility to grade the level of malignancy the cartilaginous tumors under investigation.","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80062302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
*Correspondence to: Mansour Mirzaie DDS. M.Sc (Periodontics), Private clinic in Germany, E-mail: mansoordent@yahoo.com Received: May 08, 2020; Accepted: May 20, 2020; Published: May 22, 2020 Introduction Dental implants are nowadays one the best and most popular substitute alternatives to replace extracted teeth. The restoration of teeth with implants and subsequent supraconstruction with removable or fixed prosthetics is a technique sensitive procedure. Several factors may affect the final outcome of the treatment such as: 1-quality and quantity of implant surrounding bone 2correct angulation of implants 3soft tissue biotype 4depth of inserted implant 5fabrication of the prosthetic part Although most recent technology like cbct, surgical guides and simulation computer software enables the technicians more predictable placement of implants, we face pretty often implants, which must be removed. Improper angulation of inserted implants may lead to: AInsufficient bone support around the implant Binsufficient soft tissue stability and subsequently anticipated Periimplantitis after loading. Cundesired occlusal overloading Dunsatisfying aesthetic outcomes ELack of proper occlusal function Therefore, is the removal and replacing the implant in such cases the best solution. Conventional methods to remove implants, which are fully integrated with the surrounding bone such as utilizing trephine burs, high Speed burs, forceps, piezo tips and counter-torque ratchet lead to: Aenormously bone loss around the implant Bjeopardizing critical anatomical structures like vessels and nerves Cmaking a simultaneous replacement impossible In a method developing by myself are all above mentioned factors excluded. Materials and methods Monopolar electrosurgery device A patient with 8 inserted implants in lower jaw was referred to me for making ginvivoplsty. The patient forgot to stop ASAmedication 4 days pre-op so I made the gingivoplaty via electrosurgery device. The device was set at cutting mode with an intensity of 6-7. There were small corrections to take on all implants besides the one substituting tooth 34. This implant got disintegrated after seven days, so I could unscrew it with a ratchet without utilizing any force. After removing the implant the socket was checked with a perioprobe and a bone curette, whereby no signs of necrosis were to observe. In the same session another implant was inserted in the same socket with a 0,4 mm thicker diameter, which got integrated completely after three months. 47 implants were removed within one year and half with the same method. In all cases was a simultaneous replacement possible. Conclusion Utilizing electrosurgery sets in cutting mode with an intensity of 6-7 enables the practitioner to remove an implant after one week without any damage to surrounding tissues and simultaneous replacement of it. Most important issue by using this technique is to jab the implant neck circumferential. In almost all cases were 5-6 touches
{"title":"Removal of malpositioned implants","authors":"M. Mirzaie","doi":"10.15761/DOMR.1000346","DOIUrl":"https://doi.org/10.15761/DOMR.1000346","url":null,"abstract":"*Correspondence to: Mansour Mirzaie DDS. M.Sc (Periodontics), Private clinic in Germany, E-mail: mansoordent@yahoo.com Received: May 08, 2020; Accepted: May 20, 2020; Published: May 22, 2020 Introduction Dental implants are nowadays one the best and most popular substitute alternatives to replace extracted teeth. The restoration of teeth with implants and subsequent supraconstruction with removable or fixed prosthetics is a technique sensitive procedure. Several factors may affect the final outcome of the treatment such as: 1-quality and quantity of implant surrounding bone 2correct angulation of implants 3soft tissue biotype 4depth of inserted implant 5fabrication of the prosthetic part Although most recent technology like cbct, surgical guides and simulation computer software enables the technicians more predictable placement of implants, we face pretty often implants, which must be removed. Improper angulation of inserted implants may lead to: AInsufficient bone support around the implant Binsufficient soft tissue stability and subsequently anticipated Periimplantitis after loading. Cundesired occlusal overloading Dunsatisfying aesthetic outcomes ELack of proper occlusal function Therefore, is the removal and replacing the implant in such cases the best solution. Conventional methods to remove implants, which are fully integrated with the surrounding bone such as utilizing trephine burs, high Speed burs, forceps, piezo tips and counter-torque ratchet lead to: Aenormously bone loss around the implant Bjeopardizing critical anatomical structures like vessels and nerves Cmaking a simultaneous replacement impossible In a method developing by myself are all above mentioned factors excluded. Materials and methods Monopolar electrosurgery device A patient with 8 inserted implants in lower jaw was referred to me for making ginvivoplsty. The patient forgot to stop ASAmedication 4 days pre-op so I made the gingivoplaty via electrosurgery device. The device was set at cutting mode with an intensity of 6-7. There were small corrections to take on all implants besides the one substituting tooth 34. This implant got disintegrated after seven days, so I could unscrew it with a ratchet without utilizing any force. After removing the implant the socket was checked with a perioprobe and a bone curette, whereby no signs of necrosis were to observe. In the same session another implant was inserted in the same socket with a 0,4 mm thicker diameter, which got integrated completely after three months. 47 implants were removed within one year and half with the same method. In all cases was a simultaneous replacement possible. Conclusion Utilizing electrosurgery sets in cutting mode with an intensity of 6-7 enables the practitioner to remove an implant after one week without any damage to surrounding tissues and simultaneous replacement of it. Most important issue by using this technique is to jab the implant neck circumferential. In almost all cases were 5-6 touches ","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88770851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In the current study, thermoplasmonic characteristics of Praseodymium nanoparticles with spherical, core-shell and rod shapes are investigated. In order to investigate these characteristics, interaction of synchrotron radiation emission as a function of the beam energy and Praseodymium nanoparticles were simulated using 3D finite element method. Firstly, absorption and extinction cross sections were calculated. Then, increases in temperature due to synchrotron radiation emission as a function of the beam energy absorption were calculated in Praseodymium nanoparticles by solving heat equation. The obtained results show that Praseodymium nanorods are more appropriate option for using in optothermal human cancer cells, tissues and tumors treatment method.
{"title":"Study of exclusively focused on translational aspects of praseodymium nanoparticles drug delivery under super contorted tubular polar areas of magnetic fields as optothermal human gum cancer cells, tissues and tumors treatment technique under synchrotron radiation","authors":"A. Heidari, K. Schmitt, M. Henderson, E. Besana","doi":"10.15761/DOMR.1000344","DOIUrl":"https://doi.org/10.15761/DOMR.1000344","url":null,"abstract":"In the current study, thermoplasmonic characteristics of Praseodymium nanoparticles with spherical, core-shell and rod shapes are investigated. In order to investigate these characteristics, interaction of synchrotron radiation emission as a function of the beam energy and Praseodymium nanoparticles were simulated using 3D finite element method. Firstly, absorption and extinction cross sections were calculated. Then, increases in temperature due to synchrotron radiation emission as a function of the beam energy absorption were calculated in Praseodymium nanoparticles by solving heat equation. The obtained results show that Praseodymium nanorods are more appropriate option for using in optothermal human cancer cells, tissues and tumors treatment method.","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90929627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In the current paper, investigation of the internal structure and dynamics of gum cancer cells, tissues and tumors by 13C–NMR spectra of DNA/RNA of gum cancer cells as an essential structural tool for integrative studies of gum cancer cells development are studied. Internal structure and dynamics of gum cancer cells, tissues and tumors by 13C–NMR spectra of DNA/RNA of gum cancer cells as an essential structural tool for integrative studies of gum cancer cells development–based diagnostics and imaging offer many advantages over the routine clinical techniques non–invasiveness, tissue removing is not required, minimal sample processing, labeling is not required, no prior knowledge to target molecules (e.g. antibodies) is required, safety, non–ionizing electromagnetic field is used, no external dyes/ contrast agents are needed to produce human organs images. The method is faster and cheaper to perform, which will result in quicker patient diagnosis, fewer time delays, less pain, and trauma of patients, less cost to the hospital. Investigation of the internal structure and dynamics of gum cancer cells, tissues and tumors by 13C–NMR spectra of DNA/RNA of gum cancer cells as an essential structural tool for integrative studies of gum cancer cells development based methods with the sensitivity and specificity of over 90% for in vivo and ex vivo measurements might be applied to clinical practice with a positive economic impact due to reducing of false biopsy and risk of incomplete tumor resection.
{"title":"Investigation of the internal structure and dynamics of gum cancer cells, tissues and tumors by 13C–NMR spectra of DNA/RNA of gum cancer cells as an essential structural tool for integrative studies of gum cancer cells development","authors":"A. Heidari, R. Gobato","doi":"10.15761/DOMR.1000367","DOIUrl":"https://doi.org/10.15761/DOMR.1000367","url":null,"abstract":"In the current paper, investigation of the internal structure and dynamics of gum cancer cells, tissues and tumors by 13C–NMR spectra of DNA/RNA of gum cancer cells as an essential structural tool for integrative studies of gum cancer cells development are studied. Internal structure and dynamics of gum cancer cells, tissues and tumors by 13C–NMR spectra of DNA/RNA of gum cancer cells as an essential structural tool for integrative studies of gum cancer cells development–based diagnostics and imaging offer many advantages over the routine clinical techniques non–invasiveness, tissue removing is not required, minimal sample processing, labeling is not required, no prior knowledge to target molecules (e.g. antibodies) is required, safety, non–ionizing electromagnetic field is used, no external dyes/ contrast agents are needed to produce human organs images. The method is faster and cheaper to perform, which will result in quicker patient diagnosis, fewer time delays, less pain, and trauma of patients, less cost to the hospital. Investigation of the internal structure and dynamics of gum cancer cells, tissues and tumors by 13C–NMR spectra of DNA/RNA of gum cancer cells as an essential structural tool for integrative studies of gum cancer cells development based methods with the sensitivity and specificity of over 90% for in vivo and ex vivo measurements might be applied to clinical practice with a positive economic impact due to reducing of false biopsy and risk of incomplete tumor resection.","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80962059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In the current study, thermoplasmonic characteristics of Radon nanoparticles with spherical, core-shell and rod shapes are investigated. In order to investigate these characteristics, interaction of synchrotron radiation emission as a function of the beam energy and Radon nanoparticles were simulated using 3D finite element method. Firstly, absorption and extinction cross sections were calculated. Then, increases in temperature due to synchrotron radiation emission as a function of the beam energy absorption were calculated in Radon nanoparticles by solving heat equation. The obtained results show that Radon nanorods are more appropriate option for using in optothermal human cancer cells, tissues and tumors treatment method.
{"title":"Drug delivery describes the method and approach to delivering drugs or pharmaceuticals and other xenobiotics to their site of action within radon nanoparticles effects on human gum cancer cells, tissues and tumors treatment under synchrotron radiation","authors":"A. Heidari, K. Schmitt, M. Henderson, E. Besana","doi":"10.15761/domr.1000333","DOIUrl":"https://doi.org/10.15761/domr.1000333","url":null,"abstract":"In the current study, thermoplasmonic characteristics of Radon nanoparticles with spherical, core-shell and rod shapes are investigated. In order to investigate these characteristics, interaction of synchrotron radiation emission as a function of the beam energy and Radon nanoparticles were simulated using 3D finite element method. Firstly, absorption and extinction cross sections were calculated. Then, increases in temperature due to synchrotron radiation emission as a function of the beam energy absorption were calculated in Radon nanoparticles by solving heat equation. The obtained results show that Radon nanorods are more appropriate option for using in optothermal human cancer cells, tissues and tumors treatment method.","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"147 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78133385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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