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Comparison of coronal sealing of flowable composite, resin-modified glass ionomer, and mineral trioxide aggregate in endodontically treated teeth: An in-vitro study. 比较可流动复合材料、树脂改性玻璃离聚体和三氧化物矿物骨料在牙髓治疗牙齿中的冠状封闭效果:体外研究
Q2 Dentistry Pub Date : 2024-02-22 eCollection Date: 2024-01-01
Mahla Tavakoli, Solmaz Araghi, Amirhossein Fathi, Shahriar Jalalian

Background: Coronal seal is one of the essential factors that affects the success of endodontic treatment and reinforces the apical seal. The intra-orifice barrier is an efficient alternative approach to decrease coronal leakage in endodontically treated teeth and various materials have been used for this purpose. This study aimed to compare the coronal sealing of flowable composite, resin-modified glass ionomer (RMGI), and mineral trioxide aggregate (MTA) in endodontically treated teeth.

Materials and methods: In this in vitro study, 35 single-canal canine teeth were divided into five groups, including flowable composite, RMGI, MTA, positive control, and negative control groups. The teeth were filled with restorative materials according to the factory's instructions. Afterward, the samples were immersed in 2% methylene blue dye solution for 1 week at 37°C and 100% humidity condition. Finally, the teeth were sectioned longitudinally and dye penetration was measured using a stereomicroscope with ×10. Data were analyzed with Kolmogorov-Smirnov and Kruskal-Wallis tests (α = 0.05).

Results: The positive control group showed the highest amount of dye penetration compared to other groups (12.34 ± 0.46). Dye penetration in the MTA group was significantly lower (4.25 ± 0.31) compared to the RMGI group (5.94 ± 0.24) (P = 0.02). Moreover, while the dye penetration in the MTA group was lower than in the flowable composite group (5.65 ± 0.26), the difference was not statistically significant (P = 0.12).

Conclusion: MTA reduces the coronal leakage and provides an acceptable coronal seal in endodontically treated teeth, especially compared to RMGI, and therefore, using MTA as an intra-orifice barrier increases the endodontic treatment success rate.

背景:冠状密封是影响牙髓治疗成功与否的重要因素之一,同时也是加强根尖密封的重要因素。孔内屏障是减少牙髓治疗牙冠渗漏的一种有效替代方法,为此已使用了多种材料。本研究旨在比较可流动复合材料、树脂改性玻璃离聚体(RMGI)和三氧化矿骨料(MTA)在牙髓治疗牙齿中的冠状密封性:在这项体外研究中,35 颗单冠犬齿被分为五组,包括可流动复合材料组、RMGI 组、MTA 组、阳性对照组和阴性对照组。按照工厂的说明对牙齿填充修复材料。然后,将样本在 2% 亚甲蓝染料溶液中浸泡 1 周,温度为 37°C,湿度为 100% 。最后,对牙齿进行纵向切片,使用 ×10 的体视显微镜测量染料的渗透性。数据分析采用 Kolmogorov-Smirnov 和 Kruskal-Wallis 检验(α = 0.05):与其他组相比,阳性对照组的染料渗透量最高(12.34 ± 0.46)。MTA 组的染料渗透量(4.25 ± 0.31)明显低于 RMGI 组(5.94 ± 0.24)(P = 0.02)。此外,虽然 MTA 组的染料渗透率低于可流动复合材料组(5.65 ± 0.26),但差异无统计学意义(P = 0.12):结论:与 RMGI 相比,MTA 可减少牙髓治疗牙齿的冠状渗漏并提供可接受的冠状密封,因此,使用 MTA 作为孔内屏障可提高牙髓治疗的成功率。
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引用次数: 0
Comparative evaluation of antimicrobial efficacy of triple antibiotic paste and amoxicillin clavulanate paste as an intracanal medicament against Enterococcus faecalis: An in vitro study. 三联抗生素糊剂和克拉维酸阿莫西林糊剂作为龋内药物对粪肠球菌抗菌效果的比较评价:体外研究。
Q2 Dentistry Pub Date : 2024-02-22 eCollection Date: 2024-01-01
Dhandayuthapani Sasikala, Parisa Norouzi Baghkomeh, Jamaluddin Mohammed Farzan

Background: Triple antibiotic paste (TAP) is the commonly used intracanal medicament against Enterococcus faecalis. Amoxicillin clavulanate paste (ACP) is recommended as a "fall-back" antibiotic when traditional dental antibiotics fail. Literature comparing the antimicrobial efficacy of TAP and ACP in eradicating E. faecalis from the root canal system is sparse; hence, this in vitro study was conducted to evaluate and compare the antimicrobial efficacy of TAP and ACP as an intracanal medicament for endodontic treatment of single-rooted permanent teeth against E. faecalis.

Materials and methods: This in vitro, experimental study evaluated 60 root samples obtained from extracted single-rooted human permanent teeth. The canal diameter was enlarged and subsequently infected with E. faecalis for 21 days. Four groups of the contaminated samples were treated with TAP, ACP, calcium hydroxide (positive control), and saline (negative control), respectively. Dentinal shavings were collected at the end of the 1st, 7th, and 10th day and inoculated in agar plates. The number of colony-forming units was determined, and the data were statistically analyzed using the Kolmogorov-Smirnov and Shapiro-Wilks test. P <0.05 was considered statistically significant.

Results: The mean number of E. faecalis colony counts across all 3 test days demonstrated that TAP exhibited the highest inhibition of bacterial growth, followed by ACP which is not statistically significant (P = 1.00).

Conclusion: Considering the limitations of this in vitro study, the findings suggest that ACP could be an effective alternative intracanal medicament to TAP for endodontic therapy.

背景:三联抗生素糊剂(TAP)是抗屎肠球菌的常用冠状沟内药物。阿莫西林克拉维酸盐膏(ACP)被推荐作为传统牙科抗生素失效时的 "备用 "抗生素。比较 TAP 和 ACP 在根管系统中根除粪肠球菌的抗菌效果的文献很少;因此,我们进行了这项体外研究,以评估和比较 TAP 和 ACP 作为根管内药物在单根恒牙根管治疗中对粪肠球菌的抗菌效果:这项体外实验研究评估了从拔出的单根人类恒牙中获得的 60 个牙根样本。根管直径被扩大,随后被粪大肠杆菌感染 21 天。四组受污染的样本分别用 TAP、ACP、氢氧化钙(阳性对照)和生理盐水(阴性对照)处理。在第 1 天、第 7 天和第 10 天结束时收集牙屑,并将其接种到琼脂平板中。测定菌落形成单位的数量,并使用 Kolmogorov-Smirnov 和 Shapiro-Wilks 检验对数据进行统计分析。P 结果:所有 3 个测试日的粪大肠杆菌菌落计数平均值表明,TAP 对细菌生长的抑制率最高,其次是 ACP,但无统计学意义(P = 1.00):考虑到这项体外研究的局限性,研究结果表明 ACP 可以成为牙髓治疗中 TAP 的有效替代药物。
{"title":"Comparative evaluation of antimicrobial efficacy of triple antibiotic paste and amoxicillin clavulanate paste as an intracanal medicament against <i>Enterococcus faecalis</i>: An <i>in vitro</i> study.","authors":"Dhandayuthapani Sasikala, Parisa Norouzi Baghkomeh, Jamaluddin Mohammed Farzan","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Triple antibiotic paste (TAP) is the commonly used intracanal medicament against <i>Enterococcus</i> <i>faecalis</i>. Amoxicillin clavulanate paste (ACP) is recommended as a \"fall-back\" antibiotic when traditional dental antibiotics fail. Literature comparing the antimicrobial efficacy of TAP and ACP in eradicating <i>E.</i> <i>faecalis</i> from the root canal system is sparse; hence, this <i>in vitro</i> study was conducted to evaluate and compare the antimicrobial efficacy of TAP and ACP as an intracanal medicament for endodontic treatment of single-rooted permanent teeth against <i>E.</i> <i>faecalis.</i></p><p><strong>Materials and methods: </strong>This <i>in</i> <i>vitro</i>, experimental study evaluated 60 root samples obtained from extracted single-rooted human permanent teeth. The canal diameter was enlarged and subsequently infected with <i>E.</i> <i>faecalis</i> for 21 days. Four groups of the contaminated samples were treated with TAP, ACP, calcium hydroxide (positive control), and saline (negative control), respectively. Dentinal shavings were collected at the end of the 1<sup>st</sup>, 7<sup>th</sup>, and 10<sup>th</sup> day and inoculated in agar plates. The number of colony-forming units was determined, and the data were statistically analyzed using the Kolmogorov-Smirnov and Shapiro-Wilks test. <i>P</i> <0.05 was considered statistically significant.</p><p><strong>Results: </strong>The mean number of <i>E.</i> <i>faecalis</i> colony counts across all 3 test days demonstrated that TAP exhibited the highest inhibition of bacterial growth, followed by ACP which is not statistically significant (<i>P</i> = 1.00).</p><p><strong>Conclusion: </strong>Considering the limitations of this <i>in vitro</i> study, the findings suggest that ACP could be an effective alternative intracanal medicament to TAP for endodontic therapy.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"21 ","pages":"10"},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10929719/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140109600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of intelligent development (IQ & EQ) of children with cleft lip and palate. 唇腭裂儿童智力发展(智商和情商)比较。
Q2 Dentistry Pub Date : 2024-02-22 eCollection Date: 2024-01-01
Rasool Esmaeili Maryan, Masood Feizbakhsh, Zohreh Esmaeilian, Golnoosh Sedaghati

Background: Attention to the issue of intelligence and its promotion in children with cleft lip and cleft palate (CL and CP) is necessary to reduce their injuries in life. This study aimed to determine the intelligence quotient (IQ) and emotional intelligence (EQ) in children with CL and CP in comparison to healthy children.

Materials and methods: In this descriptive study, 140 children, including 70 children with CL and CP, were selected from the Children treated in Craniofacial and Cleft Research Center, Spearman correlation, ANOVA and 70 healthy children were selected from the Pediatric Dentistry Department of Isfahan University, in the age range of 5-9 years. After obtaining the consent of the children's parents, the Raven IQ questionnaire and the Mayer and Salovey EQ questionnaire were given to the children. Data were analyzed by the Pearson correlation coefficient tests (α =0.05).

Results: EQ score in healthy children was significantly higher than in children with CL and CP (P < 0.001). The percentage of IQ cognitive intelligence in healthy children and children with CL and CP was not significantly different (P = 0.641). In healthy children, no significant relationship was observed between cognitive intelligence IQ and EQ (r = 0.018, P = 0.882). However, among children with CL and CP, there was a significant inverse relationship between cognitive intelligence IQ and EQ (P < 0.001, r = -0.526).

Conclusion: CL and CP have no effect on IQ in children, but it does affect EQ.

背景:为了减少唇裂和腭裂儿童在生活中受到的伤害,有必要关注他们的智力问题并促进其发展。本研究旨在确定唇裂和腭裂儿童与健康儿童相比的智商(IQ)和情商(EQ):在这项描述性研究中,从颅面和唇裂研究中心接受治疗的儿童中选取了 140 名儿童,其中包括 70 名 CL 和 CP 患儿,采用斯皮尔曼相关性分析和方差分析,并从伊斯法罕大学儿童牙科系选取了 70 名健康儿童,年龄范围为 5-9 岁。在征得儿童家长的同意后,对这些儿童进行了瑞文智商问卷调查和迈尔与萨洛维情商问卷调查。数据分析采用皮尔逊相关系数检验(α =0.05):健康儿童的情商得分明显高于CL和CP儿童(P < 0.001)。健康儿童的 IQ 认知智能百分比与 CL 和 CP 儿童无显著差异(P = 0.641)。在健康儿童中,认知智能智商与情商之间没有发现明显的关系(r = 0.018,P = 0.882)。然而,在患有CL和CP的儿童中,认知智能智商与情商之间存在明显的反向关系(P < 0.001,r = -0.526):结论:CL 和 CP 对儿童的智商没有影响,但对情商有影响。
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引用次数: 0
Effect of 4-META on microtensile bond strength of cements to ceramics. 4-META 对水泥与陶瓷微拉伸粘接强度的影响
Q2 Dentistry Pub Date : 2024-02-22 eCollection Date: 2024-01-01
Maliheh Nafisifard, Homayoon Alaghehmand, Laleh Soleimani, Faraneh Mokhtarpour

Background: This study assessed the effect of different concentrations of 4-methacryloyloxyethy trimellitate anhydride (4-META) added to silane on microtensile bond strength (µTBS) of light-cure and dual-cure resin cement to hybrid and zirconia-reinforced lithium silicate ceramics.

Materials and methods: This in vitro, experimental study was conducted on 32 Celtra Duo and 32 VITA Enamic ceramics bonded to Allcem Veneer light-cure and Allcem dual-cure resin cements using silane impregnated with 4-META in 0%, 2.5%, 5%, and 10 wt% concentrations in 16 groups (n = 4). The µTBS of specimens was measured by a universal testing machine and analyzed by the Kruskal-Wallis and Mann-Whitney tests, and the mode of failure was determined under a stereomicroscope and analyzed by the Chi-square test (alpha = 0.05).

Results: The lowest mean µTBS was recorded in the Enamic ceramic group with 4-META (0%) bonded to dual-cure cement (14.26 MPa), and the highest mean µTBS was recorded in Enamic ceramic with 4-META (10%) bonded to light-cure cement (18.59 MPa) (P < 0.001). The µTBS of Celtra Duo was significantly higher than that of Enamic in bonding to light-cure cement using 4-META (2.5%) (P = 0.003). All failures (100%) were adhesive in most groups. The frequency of adhesive failure was the lowest (90%) in Celtra Duo bonded to dual-cure cement with 4-META (5%).

Conclusion: According to the results of this pilot study, the addition of 4-META (10%) to silane caused a significant improvement in µTBS to light-cure cement. The addition of 4-META in all concentrations significantly improved the µTBS to Enamic ceramic in the use of dual-cure cement; however, it had no significant effect on µTBS of Celtra Duo. Nonetheless, the results should be interpreted with caution due to the relatively small sample size.

背景:本研究评估了硅烷中添加不同浓度的 4-甲基丙烯酰氧乙基偏苯三酸酯酸酐(4-META)对混合陶瓷和氧化锆增强硅酸锂陶瓷光固化和双固化树脂水门汀微拉伸粘结强度(µTBS)的影响:这项体外实验研究针对 32 个 Celtra Duo 和 32 个 VITA Enamic 陶瓷与 Allcem Veneer 光固化和 Allcem 双固化树脂水门汀的粘结情况,使用硅烷浸渍 4-META,浓度分别为 0%、2.5%、5% 和 10 wt%,共分 16 组(n = 4)。用万能试验机测量试样的 µTBS 值,并通过 Kruskal-Wallis 和 Mann-Whitney 检验进行分析,在体视显微镜下确定失效模式,并通过 Chi-square 检验(α = 0.05)进行分析:与双固化水泥粘结的 4-META (0%) Enamic 陶瓷组的 µTBS 平均值最低(14.26 兆帕),与光固化水泥粘结的 4-META (10%) Enamic 陶瓷组的 µTBS 平均值最高(18.59 兆帕)(P < 0.001)。在与光固化水泥粘结时,使用 4-META(2.5%)的 Celtra Duo 陶瓷的 µTBS 明显高于 Enamic 陶瓷(P = 0.003)。在大多数组中,所有失败(100%)都是粘接失败。Celtra Duo与使用4-META的双固化水门汀(5%)粘接失败的频率最低(90%):根据这项试验研究的结果,在硅烷中添加 4-META(10%)可显著改善光固化水泥的 µTBS 性能。在使用双固化水门汀时,添加所有浓度的 4-META 都能明显改善 Enamic 陶瓷的 µTBS 值;但对 Celtra Duo 的 µTBS 值没有明显影响。尽管如此,由于样本量相对较小,在解释结果时仍需谨慎。
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引用次数: 0
Effect of polishing versus glazing of CAD-CAM ceramics on wear and surface roughness of opposing composite resin. CAD-CAM 陶瓷的抛光与上釉对对位复合树脂的磨损和表面粗糙度的影响。
Q2 Dentistry Pub Date : 2024-02-22 eCollection Date: 2024-01-01
Mina Sadat Khoramian Esfahani, Ghazaleh Ahmadi, Behnaz Esmaeili

Background: This study aimed to assess the effect of polishing versus glazing of computer-aided design-computer-aided manufacturing (CAD-CAM) ceramics on depth of wear and surface roughness of opposing composite resin.

Materials and methods: This in vitro study was conducted on 40 Z250 composite and 40 CAD-CAM ceramic specimens including Celtra Duo, Vita Mark II, e.max CAD, and Vita Suprinity ceramics. All ceramic specimens were roughened by a fine-grit bur after primary glazing to simulate an adjusted surface in the clinical setting. They were then randomly assigned to two subgroups and underwent reglazing or polishing. All composite and ceramic specimens underwent profilometry after surface treatment and prior to the wear test, and the results were recorded quantitatively. Composite specimens were then subjected to 120,000 wear cycles against ceramic specimens in a chewing simulator, and the depth of wear was measured by a scanner. Data were statistically analyzed by repeated measures two-way analysis of variance (ANOVA) and one-way ANOVA (α = 0.05).

Results: Comparison of the surface roughness of composite specimens before and after the wear test revealed significant differences in both glazed Suprinity (P = 0.048) and Vita Mark II (P = 0.026) ceramics groups. The change in surface roughness after the wear test (compared with baseline) was significant in glazed (P = 0.000) and polished (P = 0.013) Vita Mark II and polished Suprinity (P = 0.037) ceramics, but this change was not significant in other ceramics (P > 0.05). The depth of wear after the wear test was not significantly different among the ceramic and composite subgroups (P > 0.05).

Conclusion: Assessment of depth of wear and surface roughness of composite specimens showed that the polishing kits of CAD-CAM ceramics can serve as a suitable alternative to reglazing.

背景:本研究旨在评估计算机辅助设计-计算机辅助制造(CAD-CAM)陶瓷的抛光与上釉对对位复合树脂的磨损深度和表面粗糙度的影响:这项体外研究是在 40 个 Z250 复合材料和 40 个 CAD-CAM 陶瓷试样(包括 Celtra Duo、Vita Mark II、e.max CAD 和 Vita Suprinity 陶瓷)上进行的。所有陶瓷试样在初釉后都用细磨毛刺进行了粗化处理,以模拟临床环境中的调整表面。然后将它们随机分配到两个亚组,并进行重新上釉或抛光。所有复合材料和陶瓷试样在表面处理后和磨损测试前都进行了轮廓测量,并对结果进行了定量记录。然后在咀嚼模拟器中对复合材料试样和陶瓷试样进行 120,000 次磨损循环,并用扫描仪测量磨损深度。数据采用重复测量双向方差分析(ANOVA)和单向方差分析(α = 0.05)进行统计分析:比较磨损测试前后复合材料试样的表面粗糙度发现,釉面 Suprinity(P = 0.048)和 Vita Mark II(P = 0.026)陶瓷组的表面粗糙度差异显著。磨损测试后表面粗糙度的变化(与基线相比)在上釉(P = 0.000)和抛光(P = 0.013)的 Vita Mark II 陶瓷和抛光的 Suprinity(P = 0.037)陶瓷中显著,但在其他陶瓷中变化不显著(P > 0.05)。磨损测试后的磨损深度在陶瓷和复合材料亚组中没有明显差异(P > 0.05):对复合材料试样的磨损深度和表面粗糙度的评估表明,CAD-CAM 陶瓷的抛光套件可以作为重新上釉的合适替代品。
{"title":"Effect of polishing versus glazing of CAD-CAM ceramics on wear and surface roughness of opposing composite resin.","authors":"Mina Sadat Khoramian Esfahani, Ghazaleh Ahmadi, Behnaz Esmaeili","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to assess the effect of polishing versus glazing of computer-aided design-computer-aided manufacturing (CAD-CAM) ceramics on depth of wear and surface roughness of opposing composite resin.</p><p><strong>Materials and methods: </strong>This <i>in vitro</i> study was conducted on 40 Z250 composite and 40 CAD-CAM ceramic specimens including Celtra Duo, Vita Mark II, e.max CAD, and Vita Suprinity ceramics. All ceramic specimens were roughened by a fine-grit bur after primary glazing to simulate an adjusted surface in the clinical setting. They were then randomly assigned to two subgroups and underwent reglazing or polishing. All composite and ceramic specimens underwent profilometry after surface treatment and prior to the wear test, and the results were recorded quantitatively. Composite specimens were then subjected to 120,000 wear cycles against ceramic specimens in a chewing simulator, and the depth of wear was measured by a scanner. Data were statistically analyzed by repeated measures two-way analysis of variance (ANOVA) and one-way ANOVA (α = 0.05).</p><p><strong>Results: </strong>Comparison of the surface roughness of composite specimens before and after the wear test revealed significant differences in both glazed Suprinity (<i>P</i> = 0.048) and Vita Mark II (<i>P</i> = 0.026) ceramics groups. The change in surface roughness after the wear test (compared with baseline) was significant in glazed (<i>P</i> = 0.000) and polished (<i>P</i> = 0.013) Vita Mark II and polished Suprinity (<i>P</i> = 0.037) ceramics, but this change was not significant in other ceramics (<i>P</i> > 0.05). The depth of wear after the wear test was not significantly different among the ceramic and composite subgroups (<i>P</i> > 0.05).</p><p><strong>Conclusion: </strong>Assessment of depth of wear and surface roughness of composite specimens showed that the polishing kits of CAD-CAM ceramics can serve as a suitable alternative to reglazing.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"21 ","pages":"18"},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10929728/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140109542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship between periodontal disease and obstructive sleep apnea in adults: A systematic review 成人牙周病与阻塞性睡眠呼吸暂停之间的关系:系统回顾
Q2 Dentistry Pub Date : 2024-02-01 DOI: 10.4103/drj.drj_568_22
Edoardo Bianchi, M. Segù, A. Toffoli, Geremia Razzini, G. Macaluso, Edoardo Manfredi
The purpose of this systematic review was to evaluate whether there are scientific evidence regarding the association between periodontitis and obstructive sleep apnea (OSA) in adults. An electronic search was performed on MEDLINE/PubMed for prospective and retrospective longitudinal studies, cohort studies, and case–control studies conducted in human adults affected by both OSA and periodontitis. Two reviewers extracted the data using a custom Excel spreadsheet. A methodological assessment of the quality of the studies was performed using the Newcastle–Ottawa Scale. Fourteen studies were included. All studies evaluated the association between periodontitis and OSA. None of the studies evaluated the cause–effect relationship. Eleven studies found a significant positive relationship between periodontitis and OSA, whereas three found no statistically significant association. Several study limitations were observed, such as lack of standardization of study groups, diagnosis of periodontitis and OSA, and differences in study design. Evidence of a plausible association between periodontitis and OSA was found. The possible relationship could be explained by systemic inflammation, oral breathing, and the comorbid relationship attributable to common risk factors. Observational and randomized controlled studies are needed to clarify the mechanism of interaction between the two conditions.
本系统综述旨在评估是否有科学证据表明牙周炎与成人阻塞性睡眠呼吸暂停(OSA)之间存在关联。我们在 MEDLINE/PubMed 上进行了电子检索,以了解针对同时患有 OSA 和牙周炎的成人进行的前瞻性和回顾性纵向研究、队列研究和病例对照研究。两名审稿人使用自定义 Excel 电子表格提取数据。采用纽卡斯尔-渥太华量表对研究质量进行了方法学评估。共纳入 14 项研究。所有研究都评估了牙周炎与 OSA 之间的关系。没有一项研究评估了因果关系。有 11 项研究发现牙周炎与 OSA 之间存在显著的正相关关系,而有 3 项研究发现两者之间没有统计学意义上的显著关联。有几项研究存在局限性,如研究群体、牙周炎和 OSA 诊断缺乏标准化,以及研究设计存在差异。有证据表明牙周炎与 OSA 之间存在似是而非的联系。这种可能的关系可以用全身炎症、口腔呼吸和共同风险因素导致的合并症关系来解释。需要进行观察性研究和随机对照研究,以明确这两种情况之间的相互作用机制。
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引用次数: 0
Comparative evaluation of antimicrobial efficacy of triple antibiotic paste and amoxicillin clavulanate paste as an intracanal medicament against Enterococcus faecalis: An in vitro study 三联抗生素糊剂和克拉维酸阿莫西林糊剂作为龋内药物对粪肠球菌抗菌效果的比较评价:体外研究
Q2 Dentistry Pub Date : 2024-02-01 DOI: 10.4103/drj.drj_144_23
Dhandayuthapani Sasikala, P. Baghkomeh, J. M. Farzan
Background: Triple antibiotic paste (TAP) is the commonly used intracanal medicament against Enterococcus faecalis. Amoxicillin clavulanate paste (ACP) is recommended as a “fall-back” antibiotic when traditional dental antibiotics fail. Literature comparing the antimicrobial efficacy of TAP and ACP in eradicating E. faecalis from the root canal system is sparse; hence, this in vitro study was conducted to evaluate and compare the antimicrobial efficacy of TAP and ACP as an intracanal medicament for endodontic treatment of single-rooted permanent teeth against E. faecalis. Materials and Methods: This in vitro, experimental study evaluated 60 root samples obtained from extracted single-rooted human permanent teeth. The canal diameter was enlarged and subsequently infected with E. faecalis for 21 days. Four groups of the contaminated samples were treated with TAP, ACP, calcium hydroxide (positive control), and saline (negative control), respectively. Dentinal shavings were collected at the end of the 1st, 7th, and 10th day and inoculated in agar plates. The number of colony-forming units was determined, and the data were statistically analyzed using the Kolmogorov–Smirnov and Shapiro–Wilks test. P <0.05 was considered statistically significant. Results: The mean number of E. faecalis colony counts across all 3 test days demonstrated that TAP exhibited the highest inhibition of bacterial growth, followed by ACP which is not statistically significant (P = 1.00). Conclusion: Considering the limitations of this in vitro study, the findings suggest that ACP could be an effective alternative intracanal medicament to TAP for endodontic therapy.
背景:三联抗生素糊剂(TAP)是抗屎肠球菌的常用冠状沟内药物。阿莫西林克拉维酸盐膏(ACP)被推荐作为传统牙科抗生素失效时的 "备用 "抗生素。比较 TAP 和 ACP 在根管系统中根除粪肠球菌的抗菌效果的文献很少;因此,本体外研究旨在评估和比较 TAP 和 ACP 作为根管治疗单根恒牙时根管内药物对粪肠球菌的抗菌效果。材料和方法:这项体外实验研究评估了从拔出的单根人类恒牙中获得的 60 个牙根样本。根管直径被扩大,随后被粪大肠杆菌感染 21 天。四组受污染的样本分别用 TAP、ACP、氢氧化钙(阳性对照)和生理盐水(阴性对照)处理。在第 1 天、第 7 天和第 10 天结束时收集牙屑,并将其接种到琼脂平板中。测定菌落形成单位的数量,并使用 Kolmogorov-Smirnov 和 Shapiro-Wilks 检验对数据进行统计分析。P<0.05为差异有统计学意义。结果所有 3 个测试日的粪大肠杆菌菌落计数平均值表明,TAP 对细菌生长的抑制率最高,其次是 ACP,但无统计学意义(P = 1.00)。结论考虑到这项体外研究的局限性,研究结果表明 ACP 可以成为牙髓治疗中 TAP 的有效替代药物。
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引用次数: 0
Evaluation of apical transportation and centering ability of three single-file systems in severely curved canals using micro-computed tomography 使用微型计算机断层扫描评估三种单管锉系统在严重弯曲运河中的根尖运输和居中能力
Q2 Dentistry Pub Date : 2024-02-01 DOI: 10.4103/drj.drj_270_23
S. Hasheminia, S. Soltani, Fateme Mohamadian, M. Saatchi, Seyed Mohsen Sadeghi
Background: This study aimed to compare the apical transportation and centering ability of One Curve, HyFlex EDM, and EdgeFile X1 in curved mesiobuccal and mesiolingual canals of mandibular first molars. Materials and Methods: In this in vitro experimental study, 60 mesiobuccal and mesiolingual canals of the mandibular first molars with a minimum length of 19 mm and 25°–40° curvature were randomly divided into three groups (n = 20) for root canal preparation with One Curve, HyFlex EDM, and EdgeFile X1. After access cavity preparation and confirming the glide path, the baseline micro-computed tomography (micro-CT) scans were obtained, and the root canals were instrumented with the respective systems according to the manufacturers’ instructions. Apical transportation and centering ability were assessed at 1, 3, 5, and 7 mm from the apex by comparing pre- and postinstrumentation micro-CT scans. One-way ANOVA, independent t-test, and Duncan's post hoc test were used to statistically compare the groups, and data were analyzed by SPSS version 24 (alpha = 0.05). Results: The three groups were not significantly different regarding apical transportation at 5 and 7 mm from the apex (P > 0.05). At 1 mm level, One Curve caused significantly lower apical transportation; while, at 3 mm level, HyFlex EDM resulted in significantly higher apical transportation (P < 0.05). No significant difference was noted in the centering ability of the three groups at 1, 3, and 5 mm from the apex (P > 0.05). At 7 mm level, EdgeFile X1 showed significantly lower centering ability (P < 0.05). Conclusion: One Curve caused lower canal transportation in the apical third compared with EdgeFile and HyFlex EDM, but no significant difference was noted among the three in the coronal third of the roots.
背景:本研究旨在比较 One Curve、HyFlex EDM 和 EdgeFile X1 在下颌第一磨牙弯曲颊中和龈中管中的根尖运输和定心能力。材料和方法:在这项体外实验研究中,将 60 个下颌第一磨牙的颊中和两侧中根管随机分为三组(n = 20),分别使用 One Curve、HyFlex EDM 和 EdgeFile X1 进行根管预备,这些中根管的最小长度为 19 毫米,弯曲度为 25°-40°。在准备通路并确认滑行路径后,获得基线显微计算机断层扫描(micro-CT)扫描结果,然后根据制造商的说明使用相应的系统对根管进行器械操作。通过比较器械前和器械后的微型计算机断层扫描图,在距根尖 1、3、5 和 7 毫米处评估根尖运输和定心能力。采用单因素方差分析、独立 t 检验和 Duncan 后检验对各组进行统计比较,并用 SPSS 24 版对数据进行分析(α = 0.05)。结果三组在距心尖 5 毫米和 7 毫米处的心尖运输量无明显差异(P > 0.05)。在距心尖 1 毫米处,One Curve 的心尖运移率明显较低;而在距心尖 3 毫米处,HyFlex EDM 的心尖运移率明显较高(P < 0.05)。在距心尖 1、3 和 5 毫米处,三组的居中能力无明显差异(P > 0.05)。在 7 毫米处,EdgeFile X1 的居中能力明显较低(P < 0.05)。结论:与 EdgeFile 和 HyFlex EDM 相比,One Curve 在根尖三分之一处造成的根管运输较低,但在根的冠状三分之一处,三者之间没有明显差异。
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引用次数: 0
Comparison of coronal sealing of flowable composite, resin-modified glass ionomer, and mineral trioxide aggregate in endodontically treated teeth: An in-vitro study 比较可流动复合材料、树脂改性玻璃离聚体和三氧化物矿物骨料在牙髓治疗牙齿中的冠状封闭效果:体外研究
Q2 Dentistry Pub Date : 2024-02-01 DOI: 10.4103/drj.drj_379_23
Mahla Tavakoli, S. Araghi, A. Fathi, Shahriar Jalalian
Background: Coronal seal is one of the essential factors that affects the success of endodontic treatment and reinforces the apical seal. The intra-orifice barrier is an efficient alternative approach to decrease coronal leakage in endodontically treated teeth and various materials have been used for this purpose. This study aimed to compare the coronal sealing of flowable composite, resin-modified glass ionomer (RMGI), and mineral trioxide aggregate (MTA) in endodontically treated teeth. Materials and Methods: In this in vitro study, 35 single-canal canine teeth were divided into five groups, including flowable composite, RMGI, MTA, positive control, and negative control groups. The teeth were filled with restorative materials according to the factory's instructions. Afterward, the samples were immersed in 2% methylene blue dye solution for 1 week at 37°C and 100% humidity condition. Finally, the teeth were sectioned longitudinally and dye penetration was measured using a stereomicroscope with ×10. Data were analyzed with Kolmogorov–Smirnov and Kruskal–Wallis tests (α = 0.05). Results: The positive control group showed the highest amount of dye penetration compared to other groups (12.34 ± 0.46). Dye penetration in the MTA group was significantly lower (4.25 ± 0.31) compared to the RMGI group (5.94 ± 0.24) (P = 0.02). Moreover, while the dye penetration in the MTA group was lower than in the flowable composite group (5.65 ± 0.26), the difference was not statistically significant (P = 0.12). Conclusion: MTA reduces the coronal leakage and provides an acceptable coronal seal in endodontically treated teeth, especially compared to RMGI, and therefore, using MTA as an intra-orifice barrier increases the endodontic treatment success rate.
背景:冠状密封是影响牙髓治疗成功与否的重要因素之一,同时也是加强根尖密封的重要因素。孔内屏障是减少牙髓治疗牙冠渗漏的一种有效替代方法,为此已使用了多种材料。本研究旨在比较可流动复合材料、树脂改性玻璃离聚体(RMGI)和三氧化矿骨料(MTA)在牙髓治疗牙齿中的冠状密封性。材料和方法:在这项体外研究中,35 颗单冠犬齿被分为五组,包括可流动复合材料组、RMGI 组、MTA 组、阳性对照组和阴性对照组。按照工厂的说明在牙齿上填充修复材料。然后,将样本在 2% 亚甲蓝染料溶液中浸泡 1 周,温度为 37°C,湿度为 100% 。最后,对牙齿进行纵向切片,使用 ×10 的体视显微镜测量染料的渗透性。数据分析采用 Kolmogorov-Smirnov 和 Kruskal-Wallis 检验(α = 0.05)。结果与其他组相比,阳性对照组的染料渗透量最高(12.34 ± 0.46)。MTA 组的染料渗透量(4.25 ± 0.31)明显低于 RMGI 组(5.94 ± 0.24)(P = 0.02)。此外,虽然 MTA 组的染料渗透率低于可流动复合材料组(5.65 ± 0.26),但差异无统计学意义(P = 0.12)。结论:与 RMGI 相比,MTA 可减少牙髓治疗牙齿的冠状渗漏并提供可接受的冠状密封,因此,使用 MTA 作为孔内屏障可提高牙髓治疗的成功率。
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引用次数: 0
Evaluation of taste score and fungiform papillae quantification using digital image analysis in COVID-19 patients with smell and taste dysfunction 利用数字图像分析法评估 COVID-19 嗅觉和味觉功能障碍患者的味觉评分和真菌乳头量化情况
Q2 Dentistry Pub Date : 2024-02-01 DOI: 10.4103/drj.drj_163_23
Vidya Chikkarahalli Srikantaiah, Anil Somashekara Bilimale, V. Doddawad, S. Marulaiah, H. B. Gowdappa, Ranjitha Shankaregowda, Basavegowda Madhu, A. Thotambailu, R. Achar
The COVID-19 pandemic which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has created a major global health crisis in recent years. Despite this, there have been few studies that have utilized reliable methods to assess changes in taste and smell perception. Therefore, our study aims at the number of fungiform papillae and objective measures of taste perception relationship among COVID-19 patients with olfactory and gustatory disorders. This was a cross-sectional analytical study in which 57 COVID-19 patients were recruited who confirmed the dysfunction of taste and smell. Objective assessment of the sense of taste was evaluated using four different standardized solution preparations, and the scores were given according to the patient's statements. Digitalized quantification of fungiform papillae was counted. The data were analyzed with the Pearson's correlation coefficient using the SPSS version. 23 [Licensed JSSAHER, Mysuru, Karnataka, India], and the level of significance was set at <0.001. In terms of altered or reduced taste and smell, male patients exhibited a higher incidence compared to females. Compared to the sour taste, a substantial number of COVID-19 patients have displayed a notable decrease in their ability to taste sweet, salty, and bitter flavors. However, a statistically significant positive correlation was observed between taste scores and fungiform papillae density (r = 0.518, P < 0.001). Our Study demonstrated that the quantitative evaluation of taste perception and the count of fungiform papillae can serve as important indicators of SARS-CoV-2 infection, and could potentially help in the early detection and treatment of COVID-19 patients, as reduced taste function is a significant marker of the disease.
近年来,由严重急性呼吸系统综合症冠状病毒 2(SARS-CoV-2)引起的 COVID-19 大流行造成了重大的全球健康危机。尽管如此,很少有研究利用可靠的方法来评估味觉和嗅觉的变化。因此,我们的研究旨在对患有嗅觉和味觉障碍的 COVID-19 患者进行真菌乳头数量和味觉关系的客观测量。 这是一项横断面分析研究,共招募了 57 名确认有味觉和嗅觉功能障碍的 COVID-19 患者。使用四种不同的标准化溶液制剂对味觉进行了客观评估,并根据患者的陈述进行评分。对真菌乳头进行数字化量化计数。数据使用 SPSS 版本的皮尔逊相关系数进行分析。23 [Licensed JSSAHER, Mysuru, Karnataka, India]进行分析,显著性水平设定为<0.001。 在味觉和嗅觉改变或减弱方面,男性患者的发生率高于女性。与酸味相比,相当多的 COVID-19 患者对甜味、咸味和苦味的味觉能力明显下降。不过,味觉评分与真菌乳头密度之间存在统计学意义上的显著正相关(r = 0.518,P < 0.001)。 我们的研究表明,味觉感知的定量评估和真菌乳头的数量可作为 SARS-CoV-2 感染的重要指标,并可能有助于 COVID-19 患者的早期发现和治疗,因为味觉功能减退是该疾病的一个重要标志。
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Dental Research Journal
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