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Evaluation of dimensional changes in EndoSeal mineral trioxide aggregate and AH Plus sealers using micro-computed tomography imaging. 使用微型计算机断层扫描成像技术评估 EndoSeal 三氧化二矿骨料和 AH Plus 密封剂的尺寸变化。
Q2 Dentistry Pub Date : 2024-07-12 eCollection Date: 2024-01-01
Salma Omidi, Mostafa Dehghani, Mona Alimohamadi, Jamshid Yazdani Charati, Reihaneh Sadat Hashemi

Background: Optimal dimensional stability is required for successful root canal treatment. A sealant called EndoSeal mineral trioxide aggregate (MTA) was recently introduced to the market due to its favorable physical and chemical properties. On the other hand, AH Plus (AHP) is considered the gold-standard seal.

Materials and methods: In this ex vivo quasi-experimental study, 24 single-canal premolars extracted from humans were cleaned and shaped with a motorized and rotary file, then that is divided into two groups. The teeth of each group were filled with gutta F3 and each type of sealant. The teeth were scanned by a micro-computed tomography device after 24 h. After 7 days of storage in phosphate-buffered saline solution, the samples were re-scanned. Data were analyzed using SPSS software (version 21). Descriptive data were presented as frequency, percentage, mean, and standard deviation. The Shapiro-Wilk and Kolmogorov-Smirnov tests were used to investigate the normality of the data. The Mann-Whitney test was used to compare the two groups, and the differences were ultimately not significant. The level of significance was set at 0.05 (P < 0.05).

Results: The mean differences between sealer volumes before and after the intervention were not significantly different between the two groups indicating that the EndoSeal MTA sealer is not inferior to the gold-standard root canal sealer, AHP.

Conclusion: EndoSeal MTA can be considered a reliable sealer in endodontic treatments and be subjected to further investigation.

背景:成功的根管治疗需要最佳的尺寸稳定性。最近,一种名为 EndoSeal 的密封剂因其良好的物理和化学特性被引入市场。另一方面,AH Plus(AHP)被认为是黄金标准的封闭剂:在这项体内外准实验研究中,使用电动旋转锉对从人体拔出的 24 颗单冠前臼齿进行清洁和塑形,然后将其分为两组。每组的牙齿都填充了古塔 F3 和各种类型的封闭剂。在磷酸盐缓冲盐溶液中保存 7 天后,再次对样本进行扫描。数据使用 SPSS 软件(21 版)进行分析。描述性数据以频率、百分比、平均值和标准差表示。采用 Shapiro-Wilk 和 Kolmogorov-Smirnov 检验来研究数据的正态性。采用曼-惠特尼检验对两组数据进行比较,结果显示差异不显著。显著性水平设定为 0.05(P < 0.05):结果:干预前后两组封药量的平均差异无显著性差异,这表明 EndoSeal MTA 封药并不逊色于黄金标准根管封药 AHP:结论:在牙髓治疗中,EndoSeal MTA 可被视为一种可靠的封闭剂,有待进一步研究。
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引用次数: 0
Evaluation of the effects of Streptococcus salivarius M18 and K12 probiotic bacteria on the Streptococcus mutans in saliva: A randomized clinical trial. 唾液链球菌 M18 和 K12 益生菌对唾液中变异链球菌影响的评估:随机临床试验。
Q2 Dentistry Pub Date : 2024-07-12 eCollection Date: 2024-01-01
Firoozeh Nilchian, Mohammadreza Esrafili, Nafiseh Hosseini

Background: Various methods, including the use of probiotics, have been suggested to prevent caries. Caries, which is mainly caused by Streptococcus mutans, is one of the bacterial diseases that imposes a heavy cost on society. The present study was conducted to investigate the probiotic products available in Iranian pharmacies that are used for caries prevention.

Materials and methods: In this double-blind randomized clinical trial, 40 students of medicine and pharmacy were randomly allocated to two equal groups of intervention and control using random allocation software. The intervention group used a probiotic pill containing Streptococcus salivarius M18 and K12 bacteria every night before going to bed. The control group used a mouth freshener tablet with the same flavor as the probiotic tablet every night before going to bed. The data were analyzed by SPSS (version 24) software using descriptive statistics (central tendency and dispersion) and inferential statistics (paired t-test and independent t-test). Data were collected using Excel software, and statistical analyses were performed by SPSS software (version 24).

Results: The mean number of S. mutans in the intervention group was 754.5 cfu/mm before the intervention and 1701.5 cfu/mm after the intervention, which showed a statistically significant difference (P < 0.05). In the control group, the mean S. mutans was 683 cfu/mm at the beginning of the intervention and 659 cfu/mm at the end of the intervention, which did not indicate a statistically significant difference (P > 0.05). Moreover, the normality of data was checked by the Kolmogorov-Smirnov test.

Conclusion: The mean number of S. mutans bacteria in the group using probiotic tablets was significantly increased compared to those of the control group. However, further studies are suggested to evaluate these products.

背景:人们提出了各种预防龋齿的方法,包括使用益生菌。龋齿主要由变异链球菌引起,是给社会造成巨大损失的细菌性疾病之一。本研究旨在调查伊朗药店中用于预防龋齿的益生菌产品:在这项双盲随机临床试验中,使用随机分配软件将 40 名医学和药学专业的学生随机分配到干预组和对照组两组。干预组每晚睡前使用含有唾液链球菌 M18 和 K12 的益生菌药片。对照组每晚睡前使用与益生菌药片相同口味的口腔清新剂。数据采用 SPSS(24 版)软件进行分析,使用描述性统计(中心倾向和离散度)和推断性统计(配对 t 检验和独立 t 检验)。使用 Excel 软件收集数据,并使用 SPSS 软件(24 版)进行统计分析:结果:干预前,干预组变异杆菌的平均数量为 754.5 cfu/mm,干预后为 1701.5 cfu/mm,差异有统计学意义(P < 0.05)。在对照组中,干预开始时变异单胞菌的平均值为 683 cfu/mm,干预结束时为 659 cfu/mm,差异无统计学意义(P > 0.05)。此外,数据的正态性还通过了 Kolmogorov-Smirnov 检验:结论:与对照组相比,使用益生菌片剂组的变异杆菌平均数量明显增加。不过,建议进一步研究以评估这些产品。
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引用次数: 0
Accuracy of special histochemical staining methods in diagnosis of oral pathology: A systematic review and meta-analysis. 特殊组织化学染色法在口腔病理学诊断中的准确性:系统回顾与荟萃分析。
Q2 Dentistry Pub Date : 2024-07-12 eCollection Date: 2024-01-01
Maryam Ghelichli, Abdolhalim Rajabi, Niyayesh Mirsaeedi, Masoud Mohammadi, Sina Sohrabi, Niloufar Darabi

Clinical decision-making and biomedical research heavily rely on imaging techniques to visualize tissue morphology. To examine tissues in detail, it is necessary to use special histochemical stains to enhance contrast. This meta-analysis aimed to assess the sensitivity and specificity of these stains in diagnosing oral pathologic specimens. We conducted a search in 8 databases, including EMBASE, PubMed, Web of Science, Scopus, ProQuest, Ovid, Cinahl, and Cochrane, up to June 2022. Of 87,393 studies, 41 articles were selected for inclusion in our study. The results revealed that the specificity and sensitivity of the special histochemical stains were 86% with confidence interval (CI) 95%: 80%-90% and 83% with CI 95%: 75%-89%, respectively. Among the stains evaluated, toluidine blue, Papanicolaou, silver stain, Giemsa, Gram, feulgen, and periodic acid-Schiff (PAS) were the most frequently used for the detection of malignancy, premalignant lesions, dysplasia, and candidiasis. The specificity and sensitivity of each stain were analyzed individually, considering the type of specimen. Toluidine blue was the most commonly utilized special histochemical stain, particularly effective, for detecting malignancy, with a specificity of 97% with CI 95%: 88%-99% and sensitivity of 76% with CI 95%: 56%-89%. In conclusion, special histochemical stains are effective in diagnosing oral lesions, exhibiting reasonable specificity and sensitivity, especially in cases of premalignant and malignant lesions. Based on the reviewed articles in our study, the silver stain was identified as highly sensitive, while Giemsa and Papanicolaou stain exhibited the highest specificity.

临床决策和生物医学研究在很大程度上依赖于成像技术来观察组织形态。为了详细检查组织,有必要使用特殊的组织化学染色剂来增强对比度。这项荟萃分析旨在评估这些染色剂在诊断口腔病理标本时的敏感性和特异性。截至 2022 年 6 月,我们在 8 个数据库中进行了检索,包括 EMBASE、PubMed、Web of Science、Scopus、ProQuest、Ovid、Cinahl 和 Cochrane。在 87393 项研究中,我们选择了 41 篇文章纳入研究。结果显示,特殊组织化学染色的特异性和敏感性分别为 86%(置信区间 (CI) 95%)、80%-90% 和 83%:80%-90%和 83%(置信区间 95%):75%-89%。在所评估的染色方法中,甲苯胺蓝、巴氏染色、银染色、Giemsa、革兰氏、费尔根和周期性酸-希夫(PAS)最常用于检测恶性肿瘤、癌前病变、发育不良和念珠菌病。考虑到标本的类型,对每种染色法的特异性和敏感性进行了单独分析。甲苯胺蓝是最常用的特殊组织化学染色剂,对检测恶性病变特别有效,其特异性为 97%,CI 为 95%:特异性为 97%,CI 95%:88%-99%;敏感性为 76%,CI 95%:56%-89%:56%-89%.总之,特殊组织化学染色法能有效诊断口腔病变,表现出合理的特异性和敏感性,尤其是在癌前病变和恶性病变病例中。根据我们研究中的综述文章,银染色被认为具有高度敏感性,而革兰染色和巴氏染色则表现出最高的特异性。
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引用次数: 0
Comparative study of the pure AH Plus sealer and its combination with triple antibiotic paste at different concentrations on Enterococcus faecalis bacteria. 纯 AH Plus 封闭剂及其与不同浓度的三联抗生素糊剂组合对粪肠球菌的比较研究。
Q2 Dentistry Pub Date : 2024-07-12 eCollection Date: 2024-01-01
Amirreza Mokabberi, Sohyla Aminoroaya Yamini, Arezoo Tahmourespour, Maryam Zare Jahromi

Background: In this study, the effects of pure AH Plus sealer and its combination with triple antibiotic paste at different concentrations on Enterococcus faecalis bacteria have been investigated.

Materials and methods: This in vitro study was accomplished by the means of a triple antibiotic paste combination (minocycline, metronidazole, and ciprofloxacin) at different concentrations (0%, 1%, 5%, 10%, and 25%) with AH Plus sealer on E. faecalis bacteria. Sealers were set in an incubator for 1 h, 1 day, 3 days, and 7 days, and then 10 µL of bacteria solution was placed on all samples except the negative control group. After drying for 1 h, 250 µL brain-heart infusion broth culture medium was added, and it was cultured in solid media. Direct contact test technique was performed, and the obtained data were analyzed by 1-way ANOVA, 2-way ANOVA, 3-way ANOVA, and post hoc test least significant difference. It should be noted that the data were evaluated at the significance level of P < 0.05.

Results: The average of colony-forming unit (CFU)/mL illustrated that there were no significant differences between fresh antibiotic-sealer combination, 1-day set, and 3-day set (P = 0.525), while in sealer with 7-day set, the average of CFU/mL was notably lower than other sets (P < 0.001). The outcomes revealed a considerable variation by passing time and the number of CFU/mL was remarkably reduced (P < 0.05). The data suggested that, by increasing the concentration, the average of CFU/mL was decreased, whereas the average of CFU/mL did not have significant differences in all concentrations of the antibiotic-sealer combination compared to pure sealer (P < 0.05).

Conclusion: The concentration of 1% triple antibiotic in combination with root canal sealer may become a crucial factor for inhibiting the growth of remaining bacteria.

背景:本研究调查了纯 AH Plus 封闭剂及其与不同浓度的三联抗生素糊剂组合对粪肠球菌的影响:这项体外研究是通过在 AH Plus 封闭剂中加入不同浓度(0%、1%、5%、10% 和 25%)的三联抗生素糊剂(米诺环素、甲硝唑和环丙沙星)来实现的。将封口器在培养箱中分别放置 1 小时、1 天、3 天和 7 天,然后在除阴性对照组以外的所有样品上滴加 10 µL 菌液。干燥 1 小时后,加入 250 µL 脑心输液肉汤培养基,在固体培养基中培养。采用直接接触试验技术,对所得数据进行单因素方差分析、双因素方差分析、三因素方差分析和最小显著性差异后检验。值得注意的是,数据的显著性水平为 P < 0.05:菌落形成单位(CFU)/毫升的平均值表明,新鲜抗生素-封口机组合、1 天组和 3 天组之间没有显著差异(P = 0.525),而 7 天组封口机的菌落形成单位/毫升的平均值明显低于其他组(P < 0.001)。结果显示,不同时间段的差异很大,CFU/mL 的数量明显减少(P < 0.05)。数据表明,随着浓度的增加,CFU/mL 的平均值有所下降,而所有浓度的抗生素-封闭剂组合与纯封闭剂相比,CFU/mL 的平均值没有显著差异(P < 0.05):结论:1%三联抗生素与根管封闭剂的组合浓度可能是抑制残余细菌生长的关键因素。
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引用次数: 0
Clinical efficacy of periosteal pedicle graft as a barrier membrane in guided tissue regeneration: A systematic review and meta-analysis. 骨膜作为屏障膜引导组织再生的临床疗效:系统回顾和荟萃分析。
Q2 Dentistry Pub Date : 2024-07-12 eCollection Date: 2024-01-01
Shraddha Iyer, Sangamithra Sidharthan, Dharmarajan Gopalakrishnan, Vini Mehta, Chetana Chetana, Meghana Guruprasad, Sharvari Killedar

Background: The study aims to assess the clinical efficacy of periosteal pedicle graft (PPG) as a barrier membrane in guided tissue regeneration (GTR) for gingival recession, intrabony, and furcation defects.

Materials and methods: Electronic and hand searches were performed to identify randomized controlled/clinical trials investigating GTR using PPG, with 6-month follow-up. Primary outcomes recorded: probing depth (PD), clinical attachment level (CAL), bone fill, recession depth (RD) reduction, percentage of mean root coverage, keratinized tissue width (KTW), and bone defect area (BDA).

Results: Thirteen articles were selected; 6 for recession, 2 for furcation, and 5 for intrabony. Meta-analysis was performed whenever possible, results expressed as pooled standardized mean differences (SMDs). In recession defects, the RD pooled SMD is 0.47 (95% confidence interval (CI) = [-0.50-1.44]), KTW pooled SMD is 1.30 (95% CI = [-0.30-2.91]), favoring PPG over the comparator. In furcation defects, PD pooled SMD is 1.12 (95% CI = [-2.77-0.52]), CAL pooled SMD is 0.71 (95% CI = [-1.09-2.50]), and bone fill pooled SMD is 0.67 (95% CI = [-3.34-4.69]) favoring PPG. In intrabony defects, PD pooled SMD is 0.54 (95% CI = [-2.12-1.04]), CAL pooled SMD is 0.23 (95% CI = [-1.13-0.68]), and BDA pooled SMD is 0.37 (95% CI = [-1.58-2.31]) favoring PPG. The results were not statistically significant.

Conclusion: The current evidence indicates that PPG constitutes a valid and reliable alternative to collagen barrier membranes for successful GTR.

研究背景该研究旨在评估骨膜基底移植(PPG)作为屏障膜在引导组织再生(GTR)治疗牙龈退缩、骨内和毛面缺损中的临床疗效:材料和方法: 通过电子和人工搜索,确定了使用 PPG 研究 GTR 并进行 6 个月随访的随机对照/临床试验。主要结果包括:探查深度 (PD)、临床附着水平 (CAL)、骨填充、退缩深度 (RD) 减少、平均牙根覆盖百分比、角化组织宽度 (KTW) 和骨缺损面积 (BDA):共选取了 13 篇文章,其中 6 篇针对退缩,2 篇针对沟槽,5 篇针对骨内。在可能的情况下进行了 Meta 分析,结果以汇总的标准化均值差异(SMDs)表示。在凹陷缺损中,RD 的集合 SMD 为 0.47(95% 置信区间 (CI) = [-0.50-1.44]),KTW 的集合 SMD 为 1.30(95% 置信区间 (CI) = [-0.30-2.91]),PPG 优于对比者。在沟状缺损中,PD集合SMD为1.12(95% CI = [-2.77-0.52]),CAL集合SMD为0.71(95% CI = [-1.09-2.50]),骨填充集合SMD为0.67(95% CI = [-3.34-4.69]),PPG更胜一筹。在骨内缺损中,PD 的集合 SMD 为 0.54(95% CI = [-2.12-1.04]),CAL 的集合 SMD 为 0.23(95% CI = [-1.13-0.68]),BDA 的集合 SMD 为 0.37(95% CI = [-1.58-2.31]),PPG 更受青睐。结果无统计学意义:目前的证据表明,PPG 是成功进行 GTR 的胶原屏障膜的一种有效、可靠的替代方法。
{"title":"Clinical efficacy of periosteal pedicle graft as a barrier membrane in guided tissue regeneration: A systematic review and meta-analysis.","authors":"Shraddha Iyer, Sangamithra Sidharthan, Dharmarajan Gopalakrishnan, Vini Mehta, Chetana Chetana, Meghana Guruprasad, Sharvari Killedar","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>The study aims to assess the clinical efficacy of periosteal pedicle graft (PPG) as a barrier membrane in guided tissue regeneration (GTR) for gingival recession, intrabony, and furcation defects.</p><p><strong>Materials and methods: </strong>Electronic and hand searches were performed to identify randomized controlled/clinical trials investigating GTR using PPG, with 6-month follow-up. Primary outcomes recorded: probing depth (PD), clinical attachment level (CAL), bone fill, recession depth (RD) reduction, percentage of mean root coverage, keratinized tissue width (KTW), and bone defect area (BDA).</p><p><strong>Results: </strong>Thirteen articles were selected; 6 for recession, 2 for furcation, and 5 for intrabony. Meta-analysis was performed whenever possible, results expressed as pooled standardized mean differences (SMDs). In recession defects, the RD pooled SMD is 0.47 (95% confidence interval (CI) = [-0.50-1.44]), KTW pooled SMD is 1.30 (95% CI = [-0.30-2.91]), favoring PPG over the comparator. In furcation defects, PD pooled SMD is 1.12 (95% CI = [-2.77-0.52]), CAL pooled SMD is 0.71 (95% CI = [-1.09-2.50]), and bone fill pooled SMD is 0.67 (95% CI = [-3.34-4.69]) favoring PPG. In intrabony defects, PD pooled SMD is 0.54 (95% CI = [-2.12-1.04]), CAL pooled SMD is 0.23 (95% CI = [-1.13-0.68]), and BDA pooled SMD is 0.37 (95% CI = [-1.58-2.31]) favoring PPG. The results were not statistically significant.</p><p><strong>Conclusion: </strong>The current evidence indicates that PPG constitutes a valid and reliable alternative to collagen barrier membranes for successful GTR.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"21 ","pages":"37"},"PeriodicalIF":0.0,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11346614/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142072244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the effects of probiotic pills on the oral plaque indices: A randomized clinical trial. 益生菌药片对口腔牙菌斑指数影响的评估:随机临床试验
Q2 Dentistry Pub Date : 2024-07-12 eCollection Date: 2024-01-01
Firoozeh Nilchian, Mohammadreza Esrafili, Nafiseh Hosseini

Background: Clinical trials investigating the efficacy of oral health prevention materials have conventionally used indices to evaluate the amount of plaque on tooth surfaces. Various methods, including the use of probiotics, have been suggested to prevent oral disease. The present study was conducted to investigate the probiotic products available in Iranian pharmacies that are used for the prevention of dental disease.

Materials and methods: In this double-blind randomized clinical trial, 40 students of medicine and pharmacy were randomly allocated into two equal groups of intervention and control using random allocation software. The intervention group used a probiotic pill containing Streptococcus salivarius M18 and K12 bacteria every night before going to bed. The control group used a mouth freshener tablet with the same flavor as the probiotic tablet every night before going to bed. The mean number of Streptococcus mutans bacteria in both the groups was calculated before and after using probiotic pills. The data were staticali analyzed by descriptive statistics (central tendency and dispersion) and inferential statistics (paired t-test and independent t-test) and Kolmogorov-Smironove tests (P<0.05).

Results: The plaque index values at the beginning of the study showed no statistical differences between the intervention and control groups (P = 0.85). The plaque index values in the intervention group before and after the intervention were 0.41 and 0.75, respectively, which showed a statistically significant difference (P < 0.05). The plaque index values in the control group before and after the intervention were 0.42 and 0.42, respectively, which indicated no statistically significant difference (P > 0.05).

Conclusion: The mean plaque index in the group using probiotic tablets was significantly increased compared to those of the control group. However, further studies are suggested to evaluate these products.

背景:调查口腔健康预防材料疗效的临床试验通常使用指标来评估牙齿表面的牙菌斑数量。人们提出了包括使用益生菌在内的各种方法来预防口腔疾病。本研究旨在调查伊朗药店出售的用于预防牙病的益生菌产品:在这项双盲随机临床试验中,使用随机分配软件将 40 名医学和药学专业的学生随机分配到干预组和对照组两组。干预组每晚睡前使用含有唾液链球菌 M18 和 K12 的益生菌药片。对照组每晚睡前使用与益生菌药片口味相同的口腔清新剂。计算两组在使用益生菌药片前后的变异链球菌平均数量。数据通过描述性统计(中心倾向和离散度)、推断性统计(配对 t 检验和独立 t 检验)和 Kolmogorov-Smironove 检验(结果)进行统计分析:研究开始时的斑块指数值在干预组和对照组之间没有统计学差异(P = 0.85)。干预组干预前后的斑块指数值分别为 0.41 和 0.75,差异有统计学意义(P < 0.05)。对照组在干预前后的斑块指数值分别为 0.42 和 0.42,差异无统计学意义(P > 0.05):结论:与对照组相比,使用益生菌片组的平均牙菌斑指数明显增加。结论:与对照组相比,使用益生菌片剂组的平均牙菌斑指数明显增加,但建议进一步研究以评估这些产品。
{"title":"Evaluation of the effects of probiotic pills on the oral plaque indices: A randomized clinical trial.","authors":"Firoozeh Nilchian, Mohammadreza Esrafili, Nafiseh Hosseini","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Clinical trials investigating the efficacy of oral health prevention materials have conventionally used indices to evaluate the amount of plaque on tooth surfaces. Various methods, including the use of probiotics, have been suggested to prevent oral disease. The present study was conducted to investigate the probiotic products available in Iranian pharmacies that are used for the prevention of dental disease.</p><p><strong>Materials and methods: </strong>In this double-blind randomized clinical trial, 40 students of medicine and pharmacy were randomly allocated into two equal groups of intervention and control using random allocation software. The intervention group used a probiotic pill containing <i>Streptococcus salivarius</i> M18 and K12 bacteria every night before going to bed. The control group used a mouth freshener tablet with the same flavor as the probiotic tablet every night before going to bed. The mean number of <i>Streptococcus mutans</i> bacteria in both the groups was calculated before and after using probiotic pills. The data were staticali analyzed by descriptive statistics (central tendency and dispersion) and inferential statistics (paired <i>t</i>-test and independent <i>t</i>-test) and Kolmogorov-Smironove tests (<i>P</i><0.05).</p><p><strong>Results: </strong>The plaque index values at the beginning of the study showed no statistical differences between the intervention and control groups (<i>P</i> = 0.85). The plaque index values in the intervention group before and after the intervention were 0.41 and 0.75, respectively, which showed a statistically significant difference (<i>P</i> < 0.05). The plaque index values in the control group before and after the intervention were 0.42 and 0.42, respectively, which indicated no statistically significant difference (<i>P</i> > 0.05).</p><p><strong>Conclusion: </strong>The mean plaque index in the group using probiotic tablets was significantly increased compared to those of the control group. However, further studies are suggested to evaluate these products.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"21 ","pages":"38"},"PeriodicalIF":0.0,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11346608/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142072252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In vitro assessment of push-out bond strength of cold ceramic and mineral trioxide aggregate to root dentin. 体外评估冷陶瓷和三氧化二矿骨料与根牙本质的推出粘接强度。
Q2 Dentistry Pub Date : 2024-07-12 eCollection Date: 2024-01-01
Fatemeh Mokhtari, Laleh Akhondzadeh-Kashani, Jalil Modaresi

Background: To provide a continuous seal of the root canal, root-filling material should bond to the root canal dentin, ensuring the integrity of both the root-filling material and dentin remains in a static and functional state. The present study assessed the push-out bond strength of mineral trioxide aggregate (MTA) and cold ceramic (CC).

Materials and methods: In this laboratory trial study, 20 single-rooted, extracted human teeth without caries and cracks were selected. Each tooth was mounted in cold-curing resin. Then, 3 mm slices of mid-root dentin were obtained from each tooth. The specimens were randomly divided into two groups (n = 10) and filled with MTA ProRoot and CC. All specimens were stored for 30 days in an incubator at 37°C and 100% humidity. The push-out bond strength of the test materials was measured using a cylindrical punch with a 1-mm diameter. The punch was pushed against the test specimen at a speed of 1.0 mm/min using a universal material testing machine, extruding the filling test material. The push-out force during the test was recorded, and then, the internal surface of the teeth was examined to evaluate the mode of failure. Independent t-test and Chi-square were used to analyze the data. P < 0.05 was considered a significance threshold.

Results: The mean push-out bond strength in the CC group was 24.58 (MPa), and in MTA ProRoot, it was 23.77. No significant difference was observed between the two groups. The most frequent mode of failure in both groups was adhesive failure.

Conclusion: The two materials have adequate push-out bond strength to root dentin, and there is no difference between the bond strength and mode of failure of the two materials.

背景:为实现根管的连续密封,根充材料应与根管牙本质粘结,确保根充材料和牙本质的完整性保持静态和功能状态。本研究评估了三氧化物矿物质骨料(MTA)和冷陶瓷(CC)的推出粘接强度:在这项实验室试验研究中,选择了 20 颗没有龋齿和裂缝的单根拔牙。每颗牙齿都安装在冷固化树脂中。然后,从每颗牙齿上获取 3 毫米的中根牙本质切片。将标本随机分为两组(n = 10),分别填充 MTA ProRoot 和 CC。所有试样在 37°C 和 100% 湿度的培养箱中保存 30 天。使用直径为 1 毫米的圆柱冲头测量测试材料的推出粘接强度。使用万能材料试验机以 1.0 毫米/分钟的速度将冲头推向试样,挤出填充试样。记录测试过程中的推出力,然后检查齿的内表面,以评估失效模式。数据分析采用独立 t 检验和卡方检验。结果:CC组的平均推出粘接强度为24.58(兆帕),MTA ProRoot组为23.77。两组之间无明显差异。两组中最常见的失效模式都是粘接失效:结论:两种材料对牙根牙本质都有足够的推出粘接强度,两种材料的粘接强度和失效模式没有差异。
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引用次数: 0
Apical and lateral accuracy of intraradicular impressions made using the indirect and direct technique at three different locations: A comparative in vitro analysis. 在三个不同位置使用间接和直接技术制作的牙槽内印模的根尖和侧面准确性:体外比较分析。
Q2 Dentistry Pub Date : 2024-07-12 eCollection Date: 2024-01-01
Godwin Clovis Da Costa, Praveen Rajagopal, Meena Ajay Aras, Amanda Nadia Ferreira

Background: There is limited literature available comparing the accuracy of intraradicular impressions made with a novel hybrid impression material using the indirect and direct technique at three different locations.

Materials and methods: For this comparative in vitro analysis, postspace was prepared in 15 recently extracted teeth and impressions made with vinyl polysiloxane, polyether (PE), vinyl polyether silicone (VPES), and pattern resin. Postpatterns obtained were re-seated on the teeth and longitudinally sectioned. A binocular microscope was used to measure apical and lateral discrepancies at three locations (L1, L2, and L3). L1 at the postcore junction, L2 at the middle of the post space, and L3, 2 mm short of the apical end. The data obtained were statistically analyzed using the Statistical Package for the Social Sciences (SPSS) software. One-way analysis of variance (ANOVA) (intergroup) followed by Tukey's post hoc test with P ≤ 0.05 was used.

Results: The one-way ANOVA noted a highly significant difference at the apical location. Pattern resin had the highest apical discrepancy (151.93 ± 8.59 µm), whereas the lowest was with vinyl PE silicone (140.31 ± 11.46 µm). At L1, the highest discrepancy was seen with pattern resin (32.09 ± 2.31 µm), whereas the lowest was with the addition silicone (31.94 ± 2.54 µm). At L2, addition silicone (32.88 ± 2.81 µm) showed the highest discrepancy, whereas the lowest was with vinyl PE silicone (30.5 ± 8.79 µm). The PE group had the highest mean at the L3 location (31.38 ± 3.46 µm) and the lowest was with vinyl PE silicone (30.93 ± 2.25 µm). At all lateral locations, no significant difference was noted. Tukey's post hoc comparison showed a significant difference between pattern resin and VPES (11.62 µm) followed by pattern resin and addition silicone (11.47 µm) apically.

Conclusion: The indirect technique using VPES or addition silicone is more accurate than the direct technique at the apical location.

背景:使用一种新型混合印模材料,在三个不同位置使用间接和直接技术制作的关节内印模的准确性进行比较的文献有限:为了进行体外比较分析,在 15 颗新近拔出的牙齿上制备了后间隙,并使用乙烯基聚硅氧烷、聚醚(PE)、乙烯基聚醚硅酮(VPES)和模式树脂制作了印模。将获得的后模重新固定在牙齿上,并进行纵向切片。使用双目显微镜测量三个位置(L1、L2 和 L3)的根尖和侧面差异。L1 位于牙本质交界处,L2 位于牙本质间隙中部,L3 位于距根尖端短 2 毫米处。获得的数据使用社会科学统计软件包(SPSS)进行统计分析。采用单因素方差分析(ANOVA)(组间),然后进行 Tukey 后检验,P≤0.05:结果:单因素方差分析显示,牙尖位置的差异非常显著。花纹树脂的根尖差异最大(151.93 ± 8.59 µm),而乙烯基 PE 硅酮的根尖差异最小(140.31 ± 11.46 µm)。在 L1,图案树脂的差异最大(32.09 ± 2.31 µm),而添加硅酮的差异最小(31.94 ± 2.54 µm)。在 L2,添加硅酮(32.88 ± 2.81 µm)的差异最大,而乙烯基 PE 硅酮(30.5 ± 8.79 µm)的差异最小。在 L3 位置,PE 组的平均值最高(31.38 ± 3.46 µm),而乙烯基 PE 硅胶的平均值最低(30.93 ± 2.25 µm)。在所有侧位上,均无明显差异。Tukey's事后比较显示,模式树脂和 VPES(11.62 微米)之间存在显著差异,其次是模式树脂和添加硅酮(11.47 微米):结论:在根尖位置使用 VPES 或添加硅酮的间接技术比直接技术更准确。
{"title":"Apical and lateral accuracy of intraradicular impressions made using the indirect and direct technique at three different locations: A comparative <i>in vitro</i> analysis.","authors":"Godwin Clovis Da Costa, Praveen Rajagopal, Meena Ajay Aras, Amanda Nadia Ferreira","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>There is limited literature available comparing the accuracy of intraradicular impressions made with a novel hybrid impression material using the indirect and direct technique at three different locations.</p><p><strong>Materials and methods: </strong>For this comparative <i>in vitro</i> analysis, postspace was prepared in 15 recently extracted teeth and impressions made with vinyl polysiloxane, polyether (PE), vinyl polyether silicone (VPES), and pattern resin. Postpatterns obtained were re-seated on the teeth and longitudinally sectioned. A binocular microscope was used to measure apical and lateral discrepancies at three locations (L1, L2, and L3). L1 at the postcore junction, L2 at the middle of the post space, and L3, 2 mm short of the apical end. The data obtained were statistically analyzed using the Statistical Package for the Social Sciences (SPSS) software. One-way analysis of variance (ANOVA) (intergroup) followed by Tukey's <i>post</i> <i>hoc</i> test with <i>P</i> ≤ 0.05 was used.</p><p><strong>Results: </strong>The one-way ANOVA noted a highly significant difference at the apical location. Pattern resin had the highest apical discrepancy (151.93 ± 8.59 µm), whereas the lowest was with vinyl PE silicone (140.31 ± 11.46 µm). At L1, the highest discrepancy was seen with pattern resin (32.09 ± 2.31 µm), whereas the lowest was with the addition silicone (31.94 ± 2.54 µm). At L2, addition silicone (32.88 ± 2.81 µm) showed the highest discrepancy, whereas the lowest was with vinyl PE silicone (30.5 ± 8.79 µm). The PE group had the highest mean at the L3 location (31.38 ± 3.46 µm) and the lowest was with vinyl PE silicone (30.93 ± 2.25 µm). At all lateral locations, no significant difference was noted. Tukey's <i>post</i> <i>hoc</i> comparison showed a significant difference between pattern resin and VPES (11.62 µm) followed by pattern resin and addition silicone (11.47 µm) apically.</p><p><strong>Conclusion: </strong>The indirect technique using VPES or addition silicone is more accurate than the direct technique at the apical location.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"21 ","pages":"41"},"PeriodicalIF":0.0,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11346619/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142072282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mapping global research in dental pulp regeneration: A 10-year bibliometric analysis. 牙髓再生全球研究图谱:十年文献计量分析。
Q2 Dentistry Pub Date : 2024-07-12 eCollection Date: 2024-01-01
Yeganeh-Sadat Mostafavi, Pedram Iranmanesh, Abbasali Khademi, Raheleh Mehrabi, Fatemeh Sheikhshoaei, Masoud Mohammadi

Background: Dental pulp regeneration aims to restore the function and vitality of the dental pulp, which is the soft tissue inside the tooth. Research in this field is effective in trying to improve clinical practices and procedures. This study aimed to analyze the literature related to dental pulp regeneration and to create a documented research perspective for this field.

Materials and methods: This bibliometric study analyzes the research outputs of the subject area of dental pulp regeneration indexed in the Web of Science database between 2013 and 2023. SciMAT software was used to visualize and predict the trends in research on the topic.

Results: In general, it has been observed that the stem cell cluster consistently had the highest number of articles across all periods. As we progressed through time, the significance of this cluster continued to grow, eventually becoming a crucial component in the motor theme during the last period. In addition, a significant portion of the studies conducted during different periods focused on identifying suitable materials for scaffold formation. Various materials, including polymers and bioactive glasses, were proposed as viable options for scaffold formation in different periods.

Conclusion: Dental pulp stem cells (DPSCs), scaffold networks, growth factors, and regulatory factors are the three main factors that influence dental pulp regeneration. By analyzing maps and thematic clusters in dental pulp regeneration research, as well as considering indicators such as repetition frequency, centrality, and citation of these clusters, researchers can identify the strengths, weaknesses, and gaps in current research.

背景:牙髓再生旨在恢复牙髓(牙齿内部的软组织)的功能和活力。该领域的研究能有效改善临床实践和程序。本研究旨在分析与牙髓再生相关的文献,并为这一领域创建一个有据可查的研究视角:这项文献计量学研究分析了2013年至2023年期间被Web of Science数据库收录的牙髓再生主题领域的研究成果。结果:总体而言,牙髓再生领域的研究成果呈上升趋势:总的来说,干细胞群组在各个时期的文章数量都是最多的。随着时间的推移,该专题组的重要性不断增加,最终在最后一个时期成为运动主题的重要组成部分。此外,在不同时期进行的研究中,有很大一部分都集中在确定支架形成的合适材料上。在不同时期,包括聚合物和生物活性玻璃在内的各种材料被提出作为支架形成的可行方案:牙髓干细胞(DPSC)、支架网络、生长因子和调节因子是影响牙髓再生的三个主要因素。通过分析牙髓再生研究中的地图和主题集群,以及考虑这些集群的重复频率、中心性和引用等指标,研究人员可以找出当前研究的优势、劣势和差距。
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引用次数: 0
Comparative study of conventional exfoliative cytology and centrifuged liquid-based cytology in oral leukoplakia and oral squamous cell carcinoma patients. 口腔白斑病和口腔鳞状细胞癌患者的传统脱落细胞学和离心液基细胞学比较研究。
Q2 Dentistry Pub Date : 2024-07-04 eCollection Date: 2024-01-01
R Jayabalan, Ambika Murugesan, Sekar Balakrishnan, Maya Ramesh

Background: This study aims to compare the efficacy between conventional exfoliative cytology (EC) and centrifuged liquid-based cytology (CLBC) in control, leukoplakia, and oral squamous cell carcinoma (OSCC) patients. Oral leukoplakia and oral cancer require an early definitive diagnosis for better prognostic outcome. Oral EC, a minimally invasive technique that involves the examination of desquamated cells from the tissue surfaces used as a method of early diagnosis. CLBC is a modified technique that is used to achieve improved quality of the cytology findings.

Materials and methods: A comparative study was done in 30 subjects, of which, 10 cases from control group, 10 oral leukoplakia, and 10 OSCC cases. These subjects were selected according to the appropriate inclusion and exclusion criteria. The cases in each group underwent conventional as well as CLBC. The comparison was carried out between these groups with respect to the cellular and background stromal factors. Appropriate qualitative evaluation of the samples was collected and statistical analysis was done using the Chi-squared test. The significance level of value was P < 0.05.

Results: Significant results were obtained for certain parameters such as cellular overlap clear background, uniform distribution in control, leukoplakia, and OSCC with a P = 0.004**, P = 0.001**, P = 0.006** using CLBC.

Conclusion: CLBC is better and give clearer vision as compared to conventional cytology and can be used in the early diagnosis.

研究背景本研究旨在比较传统脱落细胞学(EC)和离心液基细胞学(CLBC)对对照组、白斑病和口腔鳞状细胞癌(OSCC)患者的疗效。口腔白斑病和口腔癌需要早期明确诊断,以获得更好的预后效果。口腔EC是一种微创技术,包括检查组织表面的脱屑细胞,可作为早期诊断的一种方法。CLBC是一种改良技术,用于提高细胞学检查结果的质量:对 30 名受试者进行了比较研究,其中对照组 10 例,口腔白斑病 10 例,OSCC 10 例。这些受试者是根据适当的纳入和排除标准挑选出来的。每组病例均接受了常规和 CLBC 检查。在细胞和背景基质因素方面对这些组别进行了比较。对样本进行适当的定性评估,并使用卡方检验进行统计分析。显著性水平为 P <0.05:结果:使用 CLBC 时,某些参数,如细胞重叠、背景清晰、对照组、白斑病和 OSCC 的均匀分布等,均有显著结果,P = 0.004**、P = 0.001**、P = 0.006**:结论:与传统细胞学相比,CLBC 效果更好,视野更清晰,可用于早期诊断。
{"title":"Comparative study of conventional exfoliative cytology and centrifuged liquid-based cytology in oral leukoplakia and oral squamous cell carcinoma patients.","authors":"R Jayabalan, Ambika Murugesan, Sekar Balakrishnan, Maya Ramesh","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>This study aims to compare the efficacy between conventional exfoliative cytology (EC) and centrifuged liquid-based cytology (CLBC) in control, leukoplakia, and oral squamous cell carcinoma (OSCC) patients. Oral leukoplakia and oral cancer require an early definitive diagnosis for better prognostic outcome. Oral EC, a minimally invasive technique that involves the examination of desquamated cells from the tissue surfaces used as a method of early diagnosis. CLBC is a modified technique that is used to achieve improved quality of the cytology findings.</p><p><strong>Materials and methods: </strong>A comparative study was done in 30 subjects, of which, 10 cases from control group, 10 oral leukoplakia, and 10 OSCC cases. These subjects were selected according to the appropriate inclusion and exclusion criteria. The cases in each group underwent conventional as well as CLBC. The comparison was carried out between these groups with respect to the cellular and background stromal factors. Appropriate qualitative evaluation of the samples was collected and statistical analysis was done using the Chi-squared test. The significance level of value was <i>P</i> < 0.05.</p><p><strong>Results: </strong>Significant results were obtained for certain parameters such as cellular overlap clear background, uniform distribution in control, leukoplakia, and OSCC with a <i>P</i> = 0.004**, <i>P</i> = 0.001**, <i>P</i> = 0.006** using CLBC.</p><p><strong>Conclusion: </strong>CLBC is better and give clearer vision as compared to conventional cytology and can be used in the early diagnosis.</p>","PeriodicalId":11016,"journal":{"name":"Dental Research Journal","volume":"21 ","pages":"28"},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11346596/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142072245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Dental Research Journal
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