Dental Research Journal最新文献

Background: The shelf life of dental restorations relies primarily on the adhesion between tooth and restorative material. Numerous dental adhesive systems have been developed to play a crucial role in enhancing this adhesion. However, the presence of any residues while applying adhesive systems may compromise the adhesive seal, affecting the properties of dental restorations. Thus, this paper aims to assess the presence of microbrush bristle remnants on bonding surfaces using total-etch and self-etch adhesive systems.

Materials and methods: In the present experimental in vitro study, 12 extracted permanent maxillary premolar teeth were decoronated and divided into two groups (n = 6). Application of self-etch adhesive system (Seventh generation) was made on the prepared specimens with the help of microbrush (Cotisen) for group I, and total-etch adhesive system (Fifth generation) was applied on the prepared specimens for group II with the same brand of micro brush (Cotisen). Each group received a standardized polymerization process. The bonding surfaces of samples were then analyzed to determine the microbrush bristle remnants. An independent sample t-test was applied to compare the mean bristle remnants between the two groups. P value was set at 0.05 (at a 0.05 level of significance).

Results: Self-etch adhesive system had a greater number of microbrush bristle remnants than the total-etch adhesive system, but the difference was not statistically significant.

Conclusion: Irrespective of the different adhesive systems being used; microbrush bristle remnants were seen in both groups. Dentists should be cautious to avoid contamination of adhesive surfaces. The presence of bristle remnants might influence the shelf life of the restorations.

Background: Clear aligner therapy (CAT) was originally introduced for minor orthodontic corrections. However, with technological advances and increasing patient demands for esthetic and comfortable treatments, its application has expanded into more complex cases, including orthognathic surgery. This narrative review explores the use of clear aligners across all phases of orthognathic treatment, such as presurgical, surgical, and postsurgical.

Materials and methods: The literature from 2000 to 2025 was analyzed, identifying 34 relevant studies.

Results: Findings indicate that CAT can effectively manage dentofacial deformities such as skeletal Class II and III malocclusions, open bites, and craniofacial anomalies when used pre- and/or postoperatively.

Conclusion: Clear aligners offer significant advantages in esthetics, oral hygiene, treatment comfort, and quality of life. The combination of surgery and CAT has been demonstrated to reduce treatment time and increase patient satisfaction without compromising skeletal stability. Although there are some limitations, such as concerns about relapse and aligner rigidity in early postoperative phases, the results of occlusal stability, periodontal health, and patient satisfaction are promising. The increasing use of CAT in orthognathic surgery cases, particularly in digitally driven interdisciplinary treatment plans, is supported by this review as an effective and patient-centered alternative to fixed appliances.

Background: Oral health plays an important role in the general health of pregnant women and their newborns. Our aim was to assess oral health-related quality of life and its association with oral health literacy and dental caries among a group of Iranian pregnant women.

Materials and methods: A cross-sectional study was conducted on 200 pregnant women attending a governmental hospital in Isfahan, Iran, applying a convenient sampling method. Self-administrated questionnaires requested information about demographics, oral health-related quality of life utilizing Oral Health Impact Profile-14 (OHIP-14), and oral health literacy. A senior dental student conducted a clinical examination to record dental caries with Decayed, Missing, and Filled Teeth (DMFT) index. Kolmogorov-Smirnov test, Mann-Whitney U-test, Kruskal-Wallis test, Spearman correlation coefficient, and logistic regression model served for analysis (P < 0.05).

Results: The prevalence of oral health impacts on quality of life was 36%. In terms of the severity, the mean score of OHIP-14 was 13.2 ± 9.0 (range: 0-38). The mean score of oral health literacy was 9.7 ± 3.2 (range: 1-16). The mean DMFT was 9.8 ± 5.2. No significant relationship existed between oral health-related quality of life and oral health literacy (P = 0.347). A higher score of OHIP-14 was revealed among participants with higher DMFT index (P = 0.003, r = 0.21). In multivariate analysis, DMFT was independently associated with the likelihood of reporting one or more oral health impacts on quality of life (P < 0.05).

Conclusions: Higher caries experience was associated with poorer oral health-related quality of life among pregnant women. Thus, it is recommended to increase quality of life through preventive measures to control the dental caries experience.

Background: Despite significant advances in dentistry, postendodontic pain is one of the problems that patients still suffer from. This study aimed to evaluate the effect of bromelain-acetaminophen combination on the reduction of postendodontic pain in teeth with symptomatic irreversible pulpitis.

Materials and methods: In this randomized double-blind clinical trial, 60 patients with mandibular first molars with irreversible pulpitis were evaluated. To homogenize the samples, patients who needed endodontic treatment of mandibular first molars with moderate severity were selected according to the American Association of Endodontists case difficulty assessment form. After endodontic treatment, half of the patients were given a placebo and 500 mg acetaminophen every 6 h, and the other half were given 500 mg Anahil capsule and 500 mg acetaminophen every 6 h until the patients' pain was ameliorated. If the patient did not feel pain, they didn't take medication, also we excluded the patients who felt pain for more than 2 days. The Visual Analog Scale (VAS) was used to measure pain before and 6, 12, 24, and 48 h after endodontic treatment. Data were analyzed by SPSS (version 22) software using t-test, Mann-Whitney, and Kaplan-Meyer tests at a 5% error level.

Results: The amount of pain decreased more in the experimental group than in the placebo group 6 and 12 h after endodontic treatment, but by controlling the effect of initial pain (P = 0.627), no significant difference was observed between the two groups in the amount of pain (P = 0.875).

Conclusion: The bromelain-acetaminophen combination did not have an added value when it comes to controlling postendodontic pain.

Background: The goal of this study was to assess the techniques used in earlier conducted clinical investigations on the chemomechanical eradication of dentinal caries, as well as to assess the variances in pain perception, the time required for complete caries excavation, and how microbiological analysis compared before and following caries removal in primary teeth for both Papacarie and Carisolv.

Materials and methods: An electronic search was conducted utilizing the databases PubMed, Google Scholar, EBSCOhost, Scopus, and the Cochrane Library. The following categories were included during the assessment process: full text randomized and controlled clinical trials published between January 2000 and December 2021 in the English language only. Adolescent and child patients with open dentinal carious lesion in primary teeth were included. The methodology of the seven clinical studies chosen was evaluated.

Results: Findings of the study reported that the microbiota in carious dentine was dramatically reduced with the Papacarie therapy, and the pain perception decreased more in the Papacarie group, whereas Carisolv treatment took longer time for complete caries excavation as compared to Papacarie.

Conclusion: In conclusion, Papacarie had a beneficial impact by decreasing pain and time taken during caries excavation in primary teeth. The tooth surface treated with Papacarie also demonstrated a reduced bacterial count as compared to Carisolv chemomechanical caries removal approach. Overall, Papacarie and Carisolv are viable minimally invasive and painless techniques for effective caries removal in pediatric patients.

Malignant tumors are able to grow at sites distant from the primary site of origin. Breast, prostate, renal, thyroid, and lung carcinomas commonly metastasize to bone. Jaw metastasis is rare but may occur more often than generally estimated. Follicular carcinomas of the thyroid gland are tumors of follicular cell differentiation that consist of a microfollicular architecture with follicles lined by cuboidal epithelial cells. It is very difficult to diagnose this type of cancer at the preoperative or intraoperative stage of treatment. Here, we report a case of follicular carcinoma of the thyroid gland who was referred due to a mandibular lesion.

Background: This study aimed to compare the efficacy of casein phosphopeptide-amorphous calcium phosphate fluoride (CPP-ACPF) and propolis-based herbal toothpaste in the treatment of dentin hypersensitivity (DH).

Materials and methods: In this clinical trial, 20 patients (7 men and 13 women) who met the inclusion criteria were randomly divided into two groups. One group received the herbal toothpaste containing propolis (Herbex^®), while the other received a paste containing CPP-ACPF (GC^® MI-Paste Plus). Two nonadjacent teeth with DH in two quadrants of each patient were assessed. The pain was determined through the visual analog scale (VAS) in cold and airblast tests before the intervention (baseline) as well as at 15 min, 1, 2, 4, and 8 weeks after the first application. Three-level mixed effect model (repeated measurement, tooth, and patients) was used to analyze the VAS score data. Estimation of fixed effect parameters with standard error and the intraclass correlation coefficient that quantifies the degree to which data at the lower level are correlated were reported. The statistical significance level was determined as P < 0.05.

Results: The mean pain intensity score after 8 weeks significantly decreased in the propolis-based toothpaste group (P < 0.001) and CPP-ACPF paste group (P < 0.001) compared with baseline. Betweenn-group comparison in the 8^th week showed a significantly lower pain score in the propolis-based toothpaste group compared with the CPP-ACPF-containing paste (P = 0.02). However, at other intervals, there were no significant differences between the two groups (P > 0.05).

Conclusion: The use of both herbal toothpaste containing propolis and CPP-ACPF-containing paste for 8 weeks effectively reduced DH, with a higher desensitizing effect experienced in the former group.

Background: This study aimed to examine the effect of sandblasting on the shear bond strength (SBS) of two adhesive systems on cervical dentin in the gingival wall of Class II restorations at two different distances.

Materials and methods: In this in vitro study, 88 intact premolars were used. After creating a natural smear layer, samples were divided into self-etch (CLEARFIL LINER BOND F) and total-etch (Adper Single Bond 2) groups (n = 44). Each group was subdivided into subgroups (n = 22) for sandblasting at 5 mm or 10 mm, with the contralateral half as control. Following sandblasting (50-μm particles, 2 bar, 2 s), the resin composite was bonded to the dentin surface, with the SBS of the samples measured using a universal testing machine. The samples were examined using a scanning electron microscope (SEM) and analyzed by an energy dispersive X-Ray (EDX). The results were analyzed using three-way repeated measures analysis of variance and Chi-square tests (α = 0.05).

Results: Sandblasting significantly reduced the SBS in both adhesive groups (P < 0.001). However, the adhesive system and distance did not significantly affect the bond strength (P > 0.05). The SEM images displayed the formation of irregularities in the smear layer, and EDX analysis revealed the presence of residual alumina particles on the blasted dentin samples.

Conclusion: Cervical dentine sandblasting reduced the adhesive SBS regardless of the 5- or 10-mm distance or the adhesive system used. Thus, sandblasting is not recommended as a method of dentin preparation before restoring cervical lesions.

Background: Clear aligner therapy (CAT) has gained popularity as an alternative to Conventional Orthodontic Treatments (COT) for its potential to reduce pain and discomfort. This systematic review and meta-analysis aimed to compare pain perception and surface electromyography (sEMG) in masticatory muscles between CAT and COT groups.

Materials and methods: A comprehensive search of multiple electronic databases was conducted to identify relevant studies. The PRISMA guidelines were employed to ensure transparency and completeness in reporting and was registered in PROSPERO (CRD42024556800).

Results: Nine studies were considered for inclusion. The meta-analysis revealed a nonsignificant difference in Visual Analog Scale scores between CAT and COT groups, with a mean difference (MD) of -2.77 (95% confidence interval [CI]: -7.25, 1.71), P = 0.23. The heterogeneity test revealed significant heterogeneity among studies (I² = 100%). In contrast, the sEMG activity scores showed a nonsignificant difference between CAT and COT groups (MD = -0.80, P = 0.60). In addition, the odds ratio for patients requiring analgesics was 0.23 (95% CI: 0.08, 0.65), P = 0.005, suggesting a significant difference between CAT and COT groups.

Conclusion: The results suggest that CAT may be associated with improved patient outcomes, including reduced pain and discomfort, as well as lower analgesic consumption. However, the evidence is not conclusive, and further research is needed to fully understand the differences between CAT and COT.

Regenerative endodontics is an expedient therapeutic strategy for necrotic teeth with open apex. The promising result of clinical research in the regenerative endodontic treatment field is published. The main goal of this case series is to present the radiographic and clinical findings of the regenerative endodontic procedure.