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The Length of Xiphoid to Fundus as a Measure of Labor Progress: A Cross-sectional Study 剑突到眼底的长度是衡量分娩进度的一项横断面研究
Q3 Medicine Pub Date : 2023-10-05 DOI: 10.2174/0115734048245070230920091849
Farzaneh Rashidi Fakari, masoumeh simbar, Hamideh Torkian Demneh, Fahimeh Rashidi Fakari, Zahra Kiani, Abbas Ebadi
Background:: Vaginal examination is widely recognized as the most common method for monitoring labor progress. However, researchers are currently exploring alternative methods, which are potentially less invasive or aggressive, to assess labor progress. background: Vaginal examination is the most common method of monitoring labor progress and alternative and less aggressive methods for evaluating labor and labor progress are under consideration. Objective:: This study aimed to assess the correlation between the length of the xiphoid to the fundus and the cervical dilation in the active phase of labor. Methods:: This cross-sectional study was conducted on 180 pregnant women in Varamin, Iran. The participants were recruited using convenience sampling. Data were collected using a researcher- made questionnaire that included specific items regarding demographic characteristics, health status, and a checklist to record the results of examinations and labor progress. The collected data were analyzed using descriptive statistics, correlation tests, and multiple linear regression with SPSS 22 software. The significance level was considered to be p <0.05. method: : This cross-sectional study was conducted on 180 pregnant women in Varamin, Iran. Sampling was done by available method. Data were collected using a researcher-made questionnaire containing demographic characteristics, health status, examination form, and delivery progress and meter. The results were analyzed by descriptive statistics, correlation and multiple linear regression with SPSS 22 software. Significance level was considered p &amp;amp;lt;0.05. Results:: A total of 174 eligible women participated in the study, with a mean age of 25.90 ± 4.56 years (mean±SD) and a mean gestational age of 39.71 ± 1.03 weeks. There was a significant negative correlation between the length of the xiphoid to the fundus and cervical dilatation (p = 0.0001, r = -0.568). Conclusions:: The study revealed a significant negative correlation between the length of the xiphoid to the fundus and the cervical dilation. Therefore, the xiphoid to fundus measurement can serve as an alternative and complementary examination in cases that need frequent vaginal examinations. conclusion: There was a significant inverse correlation between the length of xiphoid to fundus and the cervical dilation. Therefore, given this size during the labor and delivery phases, it can be used as a non-invasive method of assessing labor and delivery progress.
背景:阴道检查被广泛认为是监测产程的最常用方法。然而,研究人员目前正在探索替代方法,这些方法可能侵入性或侵略性较小,以评估分娩进展。背景:阴道检查是监测产程最常见的方法,目前正在考虑采用替代的、不那么激进的方法来评估产程和产程。目的:本研究的目的是评估剑突到底的长度与产程活跃期宫颈扩张的关系。方法:本横断面研究对伊朗瓦拉明180名孕妇进行。参与者采用方便抽样方式招募。数据收集使用研究人员制作的调查问卷,其中包括有关人口特征、健康状况的具体项目,以及记录检查结果和分娩进展的检查表。采用SPSS 22软件对收集的资料进行描述性统计、相关检验和多元线性回归分析。认为显著性水平为p <0.05。方法:本横断面研究对伊朗瓦拉明的180名孕妇进行。采用现有方法进行抽样。数据采用研究者自行制作的调查问卷收集,问卷内容包括人口统计学特征、健康状况、体检表、分娩进度和计量。采用SPSS 22统计软件进行描述性统计、相关分析和多元线性回归分析。p & lt;0.05为显著性水平。结果:共有174名符合条件的女性参与了研究,平均年龄为25.90±4.56岁(mean±SD),平均胎龄为39.71±1.03周。剑突到眼底的长度与宫颈扩张呈显著负相关(p = 0.0001, r = -0.568)。结论:本研究显示剑突到眼底的长度与宫颈扩张呈显著负相关。因此,在需要频繁阴道检查的情况下,剑突到眼底的测量可以作为一种替代和补充检查。结论:剑突至眼底长度与宫颈扩张呈显著负相关。因此,考虑到产程和分娩阶段的大小,它可以作为评估产程和分娩进展的非侵入性方法。
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引用次数: 1
Contribution of Pelvic Ultrasonography in Perimenopausal Abnormal Uterine Bleeding 盆腔超声在围绝经期异常子宫出血中的作用
Q3 Medicine Pub Date : 2023-10-05 DOI: 10.2174/0115734048255407230920072719
Radhouane Achour, Hiba Mkadmi, Rim Ben Hmid
Background: About 70% of gynecological consultations for women in perimenopause are due to metrorrhagia. In most cases, they are only the witness of hormonal disturbances resulting from a luteal deficiency. Transvaginal ultrasound is the first innocuous and available additional examination that is requested as part of an etiological assessment. Objective: Our study aims to evaluate the contribution of ultrasonography in perimenopausal metrorrhagia and investigate possible clinical-ultrasound correlation. Methods: This analytical descriptive study was carried out on 50 treated for perimenopausal metrorrhagia in the emergency department of the Tunis Maternity and Neonatology Center for four months (November 1, 2017, to February 28, 2018). We included in our study patients who were not yet postmenopausal who were ≥ 45 years of age, and who sought care for breakthrough bleeding. All patients in our study initially underwent endovaginal ultrasonography, sometimes coupled with suprapubic ultrasonography. Results: The mean age of our patients was 46.3 years. Pelvic ultrasonography revealed an enlarged uterus in 16 patients (32%), with 14 of them having fibromatous uteri measuring between 3 to 10 centimeters. The findings indicate no significant correlation between ultrasound results and bleeding abundance (P = 0.321), pelvic pain (P = 0.108), and general condition (P = 0.437). Conclusion: Endovaginal pelvic ultrasonography is a quick, painless test and is the first test to be done first in an emergency department with perimenopausal vaginal bleeding. The correlation between clinical and ultrasound findings is highly random, making it impossible to assume a well-- coded diagnostic and therapeutic presumption.
背景:围绝经期妇女约70%的妇科咨询是由于子宫出血。在大多数情况下,它们只是黄体缺乏引起的激素紊乱的见证人。经阴道超声是第一个无害的,可用的附加检查,要求作为病原学评估的一部分。目的:探讨超声在围绝经期子宫出血诊断中的作用,探讨超声与临床的相关性。方法:对2017年11月1日至2018年2月28日在突尼斯妇幼中心急诊科治疗4个月的50例围绝经期产后出血患者进行分析性描述性研究。我们的研究纳入了年龄≥45岁、未绝经且因突破性出血寻求治疗的患者。在我们的研究中,所有的患者最初都接受了阴道内超声检查,有时还伴有耻骨上超声检查。结果:患者平均年龄46.3岁。盆腔超声检查显示16例(32%)患者子宫增大,其中14例子宫纤维瘤大小在3至10厘米之间。超声检查结果与出血量(P = 0.321)、盆腔疼痛(P = 0.108)和一般情况(P = 0.437)无显著相关性。结论:阴道腔超声检查是一种快速、无痛的检查方法,是围绝经期阴道出血急诊科首选的检查方法。临床和超声检查结果之间的相关性是高度随机的,因此不可能假设一个编码良好的诊断和治疗假设。
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引用次数: 0
Regulation of Thyroid Hormone: An Important Aspect During Pregnancy 甲状腺激素的调节:怀孕期间的一个重要方面
Q3 Medicine Pub Date : 2023-09-11 DOI: 10.2174/1573404820666230908092540
Parul Pamma, Sricha Singh, Sakshi Sharma
Abstract: This paper provides a synopsis of maternal and fetal thyroid hormone stimulation during pregnancy. Treatment of thyroid illness during pregnancy is critical for avoiding negative maternal and fetal outcomes. Thyroid disorders are frequently asymptomatic and difficult to detect without specialized monitoring programs. Even mild maternal thyroid hormone insufficiency can result in fetal neurodevelopment difficulties. The thyroid is over-stimulated during pregnancy, resulting in alterations in thyroid hormone concentrations. Accurate thyroid function testing during pregnancy is crucial for both initiating thyroid hormone therapy and adjusting thyroid hormone dose in people who are already on thyroid hormone. Trimester-specific intervals are particularly critical during pregnancy, when thyroid insufficiency has been linked to poor obstetric outcomes and neuro-developmental impairments in the fetus. Knowing the natural changes in hormone concentrations that occur throughout pregnancy allows for customized supplementation of iodine when needed.
摘要:本文就妊娠期间母体和胎儿甲状腺激素的刺激进行综述。妊娠期间甲状腺疾病的治疗对于避免母体和胎儿的不良结局至关重要。甲状腺疾病通常是无症状的,没有专门的监测程序很难发现。即使轻微的母亲甲状腺激素不足也会导致胎儿神经发育困难。怀孕期间甲状腺受到过度刺激,导致甲状腺激素浓度的改变。怀孕期间准确的甲状腺功能检测对于启动甲状腺激素治疗和调整已经使用甲状腺激素的人的甲状腺激素剂量至关重要。妊娠期的特定间隔尤为重要,因为甲状腺功能不全与不良的产科结局和胎儿神经发育障碍有关。了解整个孕期激素浓度的自然变化,可以在需要时定制补充碘。
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引用次数: 0
The Value IRS-1 rs1801278G > A Polymorphism Testing in Evaluating Infertile Women with Polycystic Ovarian Syndrome: A Case-control Study IRS-1的数值多囊卵巢综合征不孕妇女的多态性检测:一项病例对照研究
Q3 Medicine Pub Date : 2023-09-06 DOI: 10.2174/1573404820666230906091306
Zeena Raad Helmi, Wassan Nori, Muna Abdul Ghani Zghair
Background: Polycystic ovary syndrome (PCOS) is a leading cause of infertility. Insulin resistance is a key element in pathogenesis. The insulin receptor causes phosphorylation of the insulin receptor substrate (IRS); IRS-1 rs1801278G > A polymorphism variant is the most common genetic variant associated with IR and PCOS. Objective: We aimed to examine the frequency of IRS-1 rs1801278G > A polymorphism variant and test its value in evaluating infertile PCOS women. Methods: A case-control study recruited 140 age and body-mass-matched participants in the university hospital, subdivided according to Rotterdam criteria into PCOS cases (70/140) and healthy controls (70/140). We collected demographic data, ultrasonic [antral follicles and endometrial thickness], hormonal [FSH, LH, AMH, E2], and genetic data by polymerase chain reaction for analysis. Result: Wild GG SNP rs1801278 G was meaningfully higher among controls (58.57%, P<0.0001). Mutant AA SNP rs1801278 was significantly higher in PCOS women (37.14%, P-value =0.0001, an odds ratio of 20.50, 95% CI (9.42-28.63) to develop PCOS. Heterogenous GA gene SNP rs1801278 showed a trend of higher frequency in PCOS patients with 44.29%; OR of 3.91, 95% CI (1.37–7.55); P = 0.422. Upon correlating infertility parameters to SNP rs1801278 G>A polymorphism, statistical differences were found with AFC, LH/FSH ratio, and serum testosterone. As for the AMH, E2, and endometrial thickness, they failed to have a statistical value. Conclusion: The significant correlation of genetic polymorphism to infertility parameters among PCOS women opens a new therapeutic and prognostic avenue that helps gynecologists tailor manganate for a better and safer outcome.
背景:多囊卵巢综合征(PCOS)是导致不孕的主要原因。胰岛素抵抗是发病的关键因素。胰岛素受体引起胰岛素受体底物(IRS)的磷酸化;IRS-1 rs1801278G;多态性变异是与IR和PCOS相关的最常见的遗传变异。目的:探讨IRS-1 rs1801278G >多态性变异及其在评价不育性多囊卵巢综合征中的价值。方法:在大学医院招募年龄和体重匹配的140例患者,按鹿特丹标准分为多囊卵巢综合征患者(70/140)和健康对照组(70/140)。我们通过聚合酶链反应收集了人口统计学数据、超声[窦卵泡和子宫内膜厚度]、激素[FSH、LH、AMH、E2]和基因数据进行分析。结果:野生GG SNP rs1801278 G在对照组中显著升高(58.57%,P<0.0001)。突变型AA SNP rs1801278在PCOS女性中显著升高(37.14%,p值=0.0001,优势比为20.50,95% CI(9.42 ~ 28.63))。异质性GA基因SNP rs1801278在PCOS患者中出现频率较高,占44.29%;OR为3.91,95% CI (1.37-7.55);P = 0.422。将不孕参数与SNP rs1801278 G>A多态性相关联,发现与AFC、LH/FSH比值、血清睾酮有统计学差异。AMH、E2、子宫内膜厚度均无统计学意义。结论:多囊卵巢综合征(PCOS)患者遗传多态性与不孕参数的显著相关性为妇科医生定制治疗方案提供了新的治疗和预后途径,以获得更好、更安全的结局。
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引用次数: 0
Psychometric Properties of the Antenatal Psychosocial Stress Scale in Turkish Pregnant Women 土耳其孕妇产前心理社会压力量表的心理测量特征
IF 0.4 Q3 Medicine Pub Date : 2023-09-01 DOI: 10.2174/1573404820666230901123419
N. A. Aypar Akbag, Yasemin Şanlı, Gamze Göke Arslan
Minimizing the stress levels of pregnant women is important to giving healthy birth and raising healthy generations. Therefore, there is a need for effective methods to diagnose stress early in pregnancy.The purpose of this research was to examine the psychometric features of the Antenatal Psychosocial Stress Scale (APSS) in pregnant Turkish women.This methodological study was conducted on 290 pregnant women.The Turkish version of the APSS based on Exploratory Factor Analysis was found to have 70.215 percent of the total variance. It had a Cronbach's alpha coefficient of 0.78. After the confirmatory factor analysis, the following were determined: χ2/df: 1.663, CFI: 0.978, RMSEA: 0.048, GFI: 0. 972.The Turkish sample found the APSS to be a valid and trustworthy assessment instrument for pregnant women.
尽量减少孕妇的压力水平对于生育健康的孩子和养育健康的后代是很重要的。因此,需要有效的方法来诊断妊娠早期的应激。本研究的目的是检查土耳其孕妇产前心理社会压力量表(APSS)的心理测量特征。这项方法学研究是对290名孕妇进行的。基于探索性因子分析的土耳其版APSS被发现具有总方差的70.215%。Cronbach’s alpha系数为0.78。经验证性因子分析,得出以下结果:χ2/df: 1.663, CFI: 0.978, RMSEA: 0.048, GFI: 0。972.土耳其样本发现APSS是一个有效的和值得信赖的评估工具,为孕妇。
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引用次数: 0
The Effect of Coronavirus Pandemic on the Treatment of Gynecological and Breast Cancers 冠状病毒大流行对妇科和乳腺癌治疗的影响
IF 0.4 Q3 Medicine Pub Date : 2023-08-25 DOI: 10.2174/1573404820666230825105243
H. Salehiniya, Z. Momenimovahed, L. Allahqoli
During the COVID-19 pandemic, various groups, including women with cancer, were affected as a high-risk group in terms of disease diagnosis and treatment. Despite the importance of therapeutic changes in cancers, such as breast and gynecological cancer, there is no comprehensive study in this regard that also refers to the coronavirus. The need for a deep understanding of the impact of coronavirus on the treatment plan of this group of patients caused the researcher to design and implement this study that aims to investigate the treatment challenge among cancer patients during the COVID-19 pandemic.To answer the study question, a comprehensive search was carried out in databases, such as PubMed, Web of Science Core Collection, and Scopus, using keywords, including cancer, gynecologic cancer, breast cancer, treatment, delay, and modification. Full-texted, English language and original articles were included in this study.In total, 27 articles were selected for the study. The findings of this study revealed that COVID-19 greatly affects the treatment of gynecology and breast cancer. These patients experience delay or modification of cancer treatment. Increased time between diagnosis and treatment, delay, change or cancellation of surgery and change in treatment plan are the most important changes in cancer treatment during the COVID-19 pandemic.The COVID-19 pandemic has had a significant impact on various aspects of gynecology and breast cancer care worldwide. In the current pandemic, there has been a significant delay in the diagnosis and treatment of gynecological and breast cancer, which, due to its higher morbidity and mortality, has made the condition more difficult for cancer patients and treatment teams.
在2019冠状病毒病大流行期间,包括癌症妇女在内的各个群体在疾病诊断和治疗方面都受到了高风险群体的影响。尽管乳腺癌和妇科癌症等癌症的治疗改变很重要,但在这方面还没有全面的研究也涉及冠状病毒。为了深入了解冠状病毒对这组患者治疗计划的影响,研究者设计并实施了这项研究,旨在调查COVID-19大流行期间癌症患者的治疗挑战。为了回答研究问题,我们在PubMed、Web of Science Core Collection、Scopus等数据库中进行了全面的检索,关键词包括癌症、妇科癌症、乳腺癌、治疗、延迟和修改。本研究包括全文、英文和原创文章。本研究共选取了27篇文章。研究结果表明,新冠病毒对妇科和乳腺癌的治疗有很大影响。这些患者经历了癌症治疗的延迟或修改。在新冠肺炎大流行期间,癌症治疗最重要的变化是诊断和治疗之间的时间延长、延迟、改变或取消手术以及改变治疗计划。COVID-19大流行对全球妇科和乳腺癌护理的各个方面产生了重大影响。在目前的大流行病中,对妇科和乳腺癌的诊断和治疗严重延误,由于发病率和死亡率较高,使癌症患者和治疗小组的病情更加困难。
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引用次数: 0
Second-trimester Uterine Artery Doppler Pulsatility Index in Singleton Pregnant Women with and without Risk of Pre-eclampsia 有和无先兆子痫风险的单胎妊娠中期子宫动脉多普勒脉搏指数
IF 0.4 Q3 Medicine Pub Date : 2023-08-23 DOI: 10.2174/1573404820666230823153426
K. Shojaei, Shima Elahian, N. Saadati, R. Jafari, M. M. Gharibvand, M. Seyedtabib, Shooka Mohammadi
Preeclampsia (PE) is gestational hypertension and one of the most serious disorders in pregnant women.This study aimed to compare second-trimester uterine artery Doppler pulsatility index (UA-PI) in singleton pregnant women with and without risk of PE.A case-control study was carried out among 200 singleton pregnant women in the second trimester of pregnancy, who were referred to Imam Hospital in Ahvaz (Iran). The data were recorded on their demographic, obstetric, clinical characteristics, and Doppler indices. The average UA-PI value was considered as the mean PI between the right and left arteries. Women who were categorized into Groups 1 and 2 had a moderate-high and low risk of PE, respectively.The mean UA-PI, right UA-PI, left UA-PI, systolic and diastolic blood pressures (BP), age, body mass index (BMI), and abdominal circumference (AC) of women in Group 1 were significantly higher than those in Group 2 (p<0.05). Furthermore, Group 1 had a higher frequency of abortions, comorbidities, abnormal UA Doppler results, and nulliparous women than Group 2 (p<0.05). Based on maternal age (<35, ≥35), BMI (<25, ≥25), comorbidities (yes, no), and nulliparity (yes, no) categories, those who were in Group 1 had a significantly higher mean systolic and diastolic BP, UA-PI, right UA-PI, and left UA-PI than their counterparts in Group 2 (P<0.001).This study declared the second-trimester UA-PI had good potential for timely prediction of PE risk in pregnant women.
先兆子痫(PE)是妊娠期高血压,是孕妇最严重的疾病之一。本研究旨在比较有和无PE风险的单胎孕妇妊娠中期子宫动脉多普勒脉搏指数(UA-PI)。对200名妊娠中期的单胎孕妇进行了病例对照研究,这些孕妇被转诊到阿瓦士(伊朗)的伊玛目医院。记录患者的人口学、产科、临床特征和多普勒指数。平均UA-PI值作为左右动脉之间的平均PI值。被分为第一组和第二组的女性分别有中高和低的PE风险。1组妇女的平均UA-PI、右UA-PI、左UA-PI、收缩压、舒张压、年龄、体重指数(BMI)、腹围(AC)均显著高于2组(p<0.05)。此外,1组流产、合并症、UA多普勒异常、无产妇女的发生率均高于2组(p<0.05)。根据产妇年龄(<35、≥35)、BMI(<25、≥25)、合并症(有、无)和无产(有、无)分类,1组患者的平均收缩压和舒张压、UA-PI、右侧UA-PI和左侧UA-PI明显高于2组(P<0.001)。本研究表明,妊娠中期UA-PI在及时预测孕妇PE风险方面具有良好的潜力。
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引用次数: 0
Predictors of Fertility Desire During COVID-19 Pandemic: A Cross-Sectional Study COVID-19大流行期间生育意愿的预测因素:一项横断面研究
IF 0.4 Q3 Medicine Pub Date : 2023-08-23 DOI: 10.2174/1573404820666230823123717
S. Ghaffari, Monirolsadate Hosseini-Tabaghdehi, Roya Nikbakht, S. Jahanfar, Z. Shahhosseini
Fertility, the most important factor in population growth, is affected by various factors, including pandemics. COVID-19 (CV) was a global challenge that spread rapidly around the world.This study aimed to investigate predictors of fertility desire during the covid virus pandemic.In this cross-sectional study, 315 women who visited health centers in northern Iran for vaccination against covid virus were recruited using convenient sampling. The participants completed the sociodemographic information, Fertility Desire Scale, and Fear of covid virus scale. Logistic regression analysis was employed to assess the predictive factors of fertility desire.The participants' mean age and marriage duration were 34.4 ± 6.7, and 7.3±11.5 years, respectively. It showed fertility desire among household women was about twofold more compared to employed ones [Odds Ratio (OR) = 1.96, p = 0.009)]. The fertility desire was decreased among more educated women (OR = 0.43, p= 0.035), women with one child (OR = 0.44, p= 0.030), and women with no infant gender preferences (OR = 0.53, p= 0.032). Fear of covid virus and any history of covid virus infection in the participants or their close relatives did not change fertility desire (P > 0.05).In conclusion, health policymakers should pay more attention to the potential effects of women's employment, their educational status, and their attitude toward infant gender preferences on fertility desire during the development of programs. Further research is needed to examine this empirical association on a global scale and its effect on trying to conceive.
生育率是人口增长中最重要的因素,它受到各种因素的影响,包括流行病。2019冠状病毒病(CV)是一场在全球迅速蔓延的全球性挑战。本研究旨在探讨covid病毒大流行期间生育意愿的预测因素。在这项横断面研究中,采用方便抽样的方法招募了315名前往伊朗北部卫生中心接种covid - 19病毒疫苗的妇女。参与者完成了社会人口统计信息、生育欲望量表和对covid病毒的恐惧量表。采用Logistic回归分析评估生育意愿的预测因素。参与者的平均年龄为34.4±6.7年,平均婚龄为7.3±11.5年。结果显示,家庭妇女的生育欲望是在职妇女的两倍左右[比值比(OR) = 1.96, p = 0.009]。受教育程度较高的女性(OR = 0.43, p= 0.035)、有一个孩子的女性(OR = 0.44, p= 0.030)和没有婴儿性别偏好的女性(OR = 0.53, p= 0.032)的生育意愿下降。受试者或其近亲属对新冠病毒的恐惧和任何新冠病毒感染史均未改变生育意愿(P > 0.05)。综上所述,卫生政策制定者在制定计划时应更多地关注妇女的就业、教育状况和对婴儿性别偏好的态度对生育意愿的潜在影响。进一步的研究需要在全球范围内检验这种经验关联及其对尝试怀孕的影响。
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引用次数: 0
Cytoreductive Surgery plus Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in patients with Advanced Ovarian Cancer: A 2-year survival analysis study 晚期卵巢癌患者的细胞减少手术加高温腹腔化疗(HIPEC): 2年生存分析研究
IF 0.4 Q3 Medicine Pub Date : 2023-08-22 DOI: 10.2174/1573404820666230822145758
Azadeh Jafari Ashtiani, F. Farzaneh, Mehrdad Bohlooli, M. Hosseini
During the last few years, Cytoreductive Surgery plus Hyperthermic Intraperitoneal Chemotherapy (HIPEC) has entered the national comprehensive cancer network guidelines as a new protocol for improving patients’ outcomes. However, there is no consensus on its long-term efficiency, and it still is under debate.This study aims to evaluate the effectiveness of Cytoreductive Surgery Plus hyperthermic intraperitoneal chemotherapy in patients with advanced ovarian cancer in Iran.Thirty patients with Stage IIIc and IV advanced ovarian cancer underwent cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy at Jam Hospital with a fixed surgical team in Tehran, Iran, from 2019 to 2021. Fourteen patients were new cases, and sixteen of them were recurrent cases. At the end of cytoreductive surgery, by using a hyperthermic intraperitoneal chemotherapy device, Cisplatin was circulated in the peritoneal cavity for 90 minutes at a dose of 80-100 mg/ m2 at 43 ° C.Among 30 patients with 54.97±10.74 years of mean age, the mean overall survival was 564.967 days, and 2-year survival rates were 66.7%. According to Fisher's exact test, there was a statistically significant relationship between disease-free after surgery and mortality rate (p=0.00). However, there was no statistically significant relationship between recurrence after surgery and mortality rate (p=0.093).Based on these findings, cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy had a survival rate of 66.7% within two years in advanced ovarian cancer patients. However, to achieve better results, careful selection of patients and complete cytoreductive surgery should be performed.
在过去的几年里,细胞减少手术加腹腔热化疗(HIPEC)作为一种改善患者预后的新方案进入了国家综合癌症网络指南。然而,对其长期效率并没有达成共识,目前仍在争论中。本研究旨在评价伊朗晚期卵巢癌患者行细胞减缩手术加腹腔内高温化疗的疗效。2019年至2021年,30例IIIc期和IV期晚期卵巢癌患者在伊朗德黑兰Jam医院固定手术团队接受了细胞减少手术加腹腔内高温化疗。其中新发病例14例,复发病例16例。手术结束后,采用腹腔热化疗装置,顺铂在腹腔循环90分钟,剂量80-100 mg/ m2,温度43℃。30例患者平均年龄54.97±10.74岁,平均总生存期564.967天,2年生存率为66.7%。根据Fisher精确检验,术后无病与死亡率之间有统计学意义的关系(p=0.00)。但术后复发率与死亡率无统计学意义(p=0.093)。基于这些发现,在晚期卵巢癌患者中,细胞减少手术加腹腔内高温化疗两年内的生存率为66.7%。然而,为了达到更好的效果,应该仔细选择患者并进行完整的细胞减少手术。
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引用次数: 0
The Effect of Shared Decision-making on Decision Self-efficacy and Decisional Conflict of Women with Low-grade Squamous Intraepithelial Lesion in Cervical Cytology: An Experimental Study 共同决策对宫颈细胞学低度鳞状上皮内病变妇女决策自我效能感和决策冲突的影响:一项实验研究
IF 0.4 Q3 Medicine Pub Date : 2023-08-22 DOI: 10.2174/1573404820666230822111839
E. Mehrabi, Saba Baharvand, M. Asghari-Jafarabadi, Roghaiyeh Nourizadeh, Niloufar Sattarzadeh Jahdi, Shiva Shamsdanesh
Women often face decisional challenges and hesitation while choosing the appropriate method to follow up on their abnormal results of cervix cytology.The present study aimed to determine the effect of shared decision-making (SDM) on decision self-efficacy (DSE) and decisional conflict (DC) about follow-up methods among women with abnormal cervix cytology results.This interventional study was performed on 54 women referred to the subspecialty clinic of gynecologic oncology. The women were assigned into intervention and control groups using a randomized block design with block sizes of 4 and 6 and an allocation ratio of 1:1. The intervention group received counseling based on the SDM and a decision aid (DA) booklet. The data collection tools included the questionnaires of the demographic and obstetrics characteristics, DC, DSE, and Decision Regret. The collected data were analyzed using SPSS24 software, and independent t-tests and ANCOVA were used.After the intervention, the total mean score of the DC in the intervention group was significantly lower than that in the control group [MD: -22.84 with 95% CI: -23.52 to -21.95, (P <0.001)]. The mean score of DSE in the intervention group was significantly higher than that in the control group [MD: 14.56 with 95% CI: 21.47 to 7.65, (P <0.001)].The present study results indicated that counseling based on the SDM effectively promotes DSE and reduces DC among women with minor abnormal cervical cytology. Therefore, it is recommended that healthcare providers use SDM for women with abnormal cervical cancer screening results.
宫颈细胞学检查结果异常后,妇女在选择合适的随访方法时往往面临决策挑战和犹豫。本研究旨在探讨共同决策(SDM)对宫颈细胞学检查结果异常女性随访方法决策自我效能感(DSE)和决策冲突(DC)的影响。本介入性研究对54名转介至妇科肿瘤亚专科诊所的妇女进行。采用随机分组设计,分组大小分别为4和6,分配比例为1:1,将妇女分为干预组和对照组。干预组接受基于SDM和决策辅助(DA)小册子的咨询。数据收集工具包括人口统计学和产科特征问卷、DC问卷、DSE问卷和决策后悔问卷。收集的资料采用SPSS24软件进行分析,采用独立t检验和方差分析。干预后,干预组DC总平均评分显著低于对照组[MD: -22.84, 95% CI: -23.52 ~ -21.95, P <0.001]。干预组DSE平均评分显著高于对照组[MD: 14.56, 95% CI: 21.47 ~ 7.65, P <0.001]。本研究结果表明,基于SDM的咨询可有效促进宫颈细胞学轻微异常妇女的DSE,降低DC。因此,建议医疗保健提供者对宫颈癌筛查结果异常的妇女使用SDM。
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Current Women s Health Reviews
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