Abstract: The complex heterogeneous disorder known as polycystic ovarian syndrome (PCOS) includes endocrine, reproductive, metabolic, psychological, and other pathological aspects. Yet, nothing is understood regarding the cause of PCOS. Insulin resistance and hyperandrogenism are major contributors to the pathophysiology of PCOS, according to various studies. Because of this, a lot of PCOS treatment regimens include changing a person's lifestyle through practices, like exercise, nutrition, and vitamin supplementation. Recent studies have indicated a number of nutrients, including vitamins, minerals, and vitamin-like substances, for the therapy of PCOS since they all have at least one functional characteristic in the pathways that are affected by PCOS. As a result, it is claimed that PCOS may be caused by a vitamin or mineral deficiency. It is the goal of this review to conduct a critical literature analysis on nutritional supplementation for the management of PCOS.
{"title":"An Exquisite Analysis on the Significance of Nutrient Supplementation in the Holistic Management of Poly-cystic Ovarian Syndrome","authors":"Rashmi Saxena Pal, Yogendra Pal, MVNL Chaitanya, Rajnish Kumar, Pankaj Tyagi, Preeti Srivastava","doi":"10.2174/0115734048262284230927191823","DOIUrl":"https://doi.org/10.2174/0115734048262284230927191823","url":null,"abstract":"Abstract: The complex heterogeneous disorder known as polycystic ovarian syndrome (PCOS) includes endocrine, reproductive, metabolic, psychological, and other pathological aspects. Yet, nothing is understood regarding the cause of PCOS. Insulin resistance and hyperandrogenism are major contributors to the pathophysiology of PCOS, according to various studies. Because of this, a lot of PCOS treatment regimens include changing a person's lifestyle through practices, like exercise, nutrition, and vitamin supplementation. Recent studies have indicated a number of nutrients, including vitamins, minerals, and vitamin-like substances, for the therapy of PCOS since they all have at least one functional characteristic in the pathways that are affected by PCOS. As a result, it is claimed that PCOS may be caused by a vitamin or mineral deficiency. It is the goal of this review to conduct a critical literature analysis on nutritional supplementation for the management of PCOS.","PeriodicalId":11030,"journal":{"name":"Current Women s Health Reviews","volume":"114 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136254097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-11DOI: 10.2174/0115734048258094230927053007
Ghiasi Ashraf, Sharaflari Fatemeh, Bagheri Leila
Background: Childbirth is an important event and special experience in women's lives. Labor pain is the most severe pain that women undergo in their lives. Pain management during labor is crucial for the well-being of the mother and fetus. Objective: This study aimed to compare the effect of combined LI4 and SP6 acupressure with SP6 acupressure on reducing labor pain. Methods: A total of 108 primiparous women who participated in the study were randomized into three groups, combining LI4 and SP6 acupressure, SP6 acupressure, and a control group. Pain intensity was evaluated before, immediately, 1 and 2 hours after the intervention and the second stage of labor by visual analogue scale (VAS). Results: Although the pain intensity immediately after the intervention was lower in the combined SP6 and LI4 acupressure group than in the other groups, the differences were not significant between the three groups (p = 0.147). The pain intensity 1 hour after the intervention and in the second stage of labor had a statistically significant difference between the three groups (p =0.006, p =0.001). The pain intensity 2 hours after the intervention was lower in the combined SP6 and LI4 acupressure group than the other groups, but it was not statistically significantly different (p= 0.05). The pain intensity 1 hour after the intervention was not statistically different between the SP6 group and the control group (p= 0.095). The pain intensity 2 hours after the intervention was lower in the combined SP6 and LI4 acupressure group compared to the control group, but it was not significant (p=0.06). The pain intensity in the second stage of labor was lower in the combined SP6 and LI4 acupressure group and SP6 acupressure group compared to the control group (p =0.001, p = 0.017), but there was no significant difference between the SP6 acupressure group and combined SP6 and LI4 acupressure group (p=1.000). Conclusion: The obtained results revealed that combination intervention is a safe, effective, noninvasive and economical method in alleviating labor pain intensity. Healthcare providers are expected to master the acupressure technique as an alternative, complementary therapy, which can be used as an alternative or additional therapy.
{"title":"Comparison of the Effects of Sanyinjiao Point (SP6) Acupressure with Combined SP6 and LI4 Acupressure on Labor Pain Intensity in Primiparous Women: A Randomized Controlled Trial","authors":"Ghiasi Ashraf, Sharaflari Fatemeh, Bagheri Leila","doi":"10.2174/0115734048258094230927053007","DOIUrl":"https://doi.org/10.2174/0115734048258094230927053007","url":null,"abstract":"Background: Childbirth is an important event and special experience in women's lives. Labor pain is the most severe pain that women undergo in their lives. Pain management during labor is crucial for the well-being of the mother and fetus. Objective: This study aimed to compare the effect of combined LI4 and SP6 acupressure with SP6 acupressure on reducing labor pain. Methods: A total of 108 primiparous women who participated in the study were randomized into three groups, combining LI4 and SP6 acupressure, SP6 acupressure, and a control group. Pain intensity was evaluated before, immediately, 1 and 2 hours after the intervention and the second stage of labor by visual analogue scale (VAS). Results: Although the pain intensity immediately after the intervention was lower in the combined SP6 and LI4 acupressure group than in the other groups, the differences were not significant between the three groups (p = 0.147). The pain intensity 1 hour after the intervention and in the second stage of labor had a statistically significant difference between the three groups (p =0.006, p =0.001). The pain intensity 2 hours after the intervention was lower in the combined SP6 and LI4 acupressure group than the other groups, but it was not statistically significantly different (p= 0.05). The pain intensity 1 hour after the intervention was not statistically different between the SP6 group and the control group (p= 0.095). The pain intensity 2 hours after the intervention was lower in the combined SP6 and LI4 acupressure group compared to the control group, but it was not significant (p=0.06). The pain intensity in the second stage of labor was lower in the combined SP6 and LI4 acupressure group and SP6 acupressure group compared to the control group (p =0.001, p = 0.017), but there was no significant difference between the SP6 acupressure group and combined SP6 and LI4 acupressure group (p=1.000). Conclusion: The obtained results revealed that combination intervention is a safe, effective, noninvasive and economical method in alleviating labor pain intensity. Healthcare providers are expected to master the acupressure technique as an alternative, complementary therapy, which can be used as an alternative or additional therapy.","PeriodicalId":11030,"journal":{"name":"Current Women s Health Reviews","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136253938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-11DOI: 10.2174/0115734048247312230929092327
Georgina N. Marchiori, Aldo R. Eynard, Elio A. Soria
Abstract: Linoleic acid (ω-6 LA) and α-linolenic acid (ω-3 ALA) are essential fatty acids (EFA) for human beings. They must be consumed through diet and then extensively metabolized, a process that plays a fundamental role in health and eventually in disease prevention. Given the numerous changes depending on age and sex, EFA metabolic adaptations require further investigations along the women’s life cycle, from onset to decline of the reproductive age. Thus, this review explains women’s life cycle stages and their involvement in diet intake, digestion and absorption, the role of microbiota, metabolism, bioavailability, and EFA fate and major metabolites. This knowledge is crucial to promoting lipid homeostasis according to female physiology through well-directed health strategies. Concerning this, the promotion of breastfeeding, nutrition, and physical activity is cardinal to counteract ALA deficiency, LA/ALA imbalance, and the release of unhealthy derivatives. These perturbations arise after menopause that compromise both lipogenic and lipolytic pathways. The close interplay of diet, age, female organism, and microbiota also plays a central role in regulating lipid metabolism. Consequently, future studies are encouraged to propose efficient interventions for each stage of women's cycle. In this sense, plant-derived foods and products are promising to be included in women’s nutrition to improve EFA metabolism.
{"title":"Essential Fatty Acids along the Women’s Life Cycle and Promotion of a Well-balanced Metabolism","authors":"Georgina N. Marchiori, Aldo R. Eynard, Elio A. Soria","doi":"10.2174/0115734048247312230929092327","DOIUrl":"https://doi.org/10.2174/0115734048247312230929092327","url":null,"abstract":"Abstract: Linoleic acid (ω-6 LA) and α-linolenic acid (ω-3 ALA) are essential fatty acids (EFA) for human beings. They must be consumed through diet and then extensively metabolized, a process that plays a fundamental role in health and eventually in disease prevention. Given the numerous changes depending on age and sex, EFA metabolic adaptations require further investigations along the women’s life cycle, from onset to decline of the reproductive age. Thus, this review explains women’s life cycle stages and their involvement in diet intake, digestion and absorption, the role of microbiota, metabolism, bioavailability, and EFA fate and major metabolites. This knowledge is crucial to promoting lipid homeostasis according to female physiology through well-directed health strategies. Concerning this, the promotion of breastfeeding, nutrition, and physical activity is cardinal to counteract ALA deficiency, LA/ALA imbalance, and the release of unhealthy derivatives. These perturbations arise after menopause that compromise both lipogenic and lipolytic pathways. The close interplay of diet, age, female organism, and microbiota also plays a central role in regulating lipid metabolism. Consequently, future studies are encouraged to propose efficient interventions for each stage of women's cycle. In this sense, plant-derived foods and products are promising to be included in women’s nutrition to improve EFA metabolism.","PeriodicalId":11030,"journal":{"name":"Current Women s Health Reviews","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136254096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-10DOI: 10.2174/0115734048255432231002061513
So Hee Park, Hayeon Kim, Jeong In Choi, Soo-Ho Chung, Jae Hong Sang
Introduction: Hemolysis, elevated liver enzymes and low platelets (HELLP) syndrome is a disease of pregnancy that occurs very rarely before 20 weeks of gestation. We report a case of HELLP syndrome developing at 14 weeks and 2 days of gestation. Case Presentation: A 33-year-old Asian primipara at 14 weeks and 2 days of gestation visited the emergency room with a fever and headache. Initial blood pressure was 140/70 mm Hg, tempera.ture 38.5°C, heart rate 130 beats/min with tachycardia. Her prenatal examination has been unre.markable, and fetal ultrasonography was within normal range. The laboratory results showed low platelet count with elevated liver enzymes, D-dimer, and fibrinogen but no sign of jaundice. Her WBC differential suggested a bacterial infection. Thus, we diagnosed early HELLP syndrome and immediately started conservative treatments. One day after admission, symptoms and laboratory results showed aggravation of the disease. We performed termination, followed by dilation and curettage for retained placenta. Her general condition improved rapidly after the operation. Placen.tal biopsy showed both acute and chronic inflammation. She also had anticardiolipin antibody IgM, and after discharge, she was referred to a rheumatology specialist to address the antiphospho.lipid syndrome issue. Discussion: Although the triggers of HELLP syndrome are unclear, a recent inflammatory hypothesis suggests that placenta-derived inflammatory cytokines are involved. In our case, the anti-cardiolipin antibody may have triggered microangiopathy of the placenta. Our analysis of published HELLP cases revealed that, apart from the three diagnostic criteria, the most common abnormal laboratory finding was antiphospholipid antibodies. Therefore, despite its rarity, if a sign of inflammation is present in a patient, it is important to consider HELLP syndrome regardless of gestational age
简介:溶血、肝酶升高和低血小板(HELLP)综合征是一种罕见的妊娠疾病，发生在妊娠20周前。我们报告一例HELLP综合征在妊娠14周和2天的发展。病例介绍:一名33岁的亚洲初产妇，妊娠14周零2天，以发烧和头痛就诊于急诊室。初始血压140/70 mm Hg，体温。体温38.5℃，心率130次/分，伴有心动过速。她的产前检查已经结束了。明显，胎儿超声检查在正常范围内。实验室结果显示血小板计数低，肝酶、d -二聚体和纤维蛋白原升高，但无黄疸迹象。她的白细胞鉴别提示是细菌感染。因此，我们早期诊断出HELLP综合征并立即开始保守治疗。入院后1天，症状及化验结果显示病情加重。我们进行了终止妊娠，随后对保留的胎盘进行了扩张和刮除。手术后她的一般情况迅速好转。Placen。活检显示急性和慢性炎症。她也有抗心磷脂抗体IgM，出院后，她被转介到风湿病专家解决抗磷问题。脂质综合征问题。讨论:尽管HELLP综合征的触发因素尚不清楚，但最近的一项炎症假说表明，胎盘源性炎症细胞因子参与其中。在我们的病例中，抗心磷脂抗体可能引发了胎盘微血管病变。我们对已发表的HELLP病例的分析显示，除了三个诊断标准外，最常见的实验室异常发现是抗磷脂抗体。因此，尽管罕见，如果患者出现炎症迹象，无论胎龄如何，考虑HELLP综合征是很重要的
{"title":"HELLP Syndrome Developing at 14 Weeks of Gestation: An Extremely Rare Case Report and a Literature Review","authors":"So Hee Park, Hayeon Kim, Jeong In Choi, Soo-Ho Chung, Jae Hong Sang","doi":"10.2174/0115734048255432231002061513","DOIUrl":"https://doi.org/10.2174/0115734048255432231002061513","url":null,"abstract":"Introduction: Hemolysis, elevated liver enzymes and low platelets (HELLP) syndrome is a disease of pregnancy that occurs very rarely before 20 weeks of gestation. We report a case of HELLP syndrome developing at 14 weeks and 2 days of gestation. Case Presentation: A 33-year-old Asian primipara at 14 weeks and 2 days of gestation visited the emergency room with a fever and headache. Initial blood pressure was 140/70 mm Hg, tempera.ture 38.5°C, heart rate 130 beats/min with tachycardia. Her prenatal examination has been unre.markable, and fetal ultrasonography was within normal range. The laboratory results showed low platelet count with elevated liver enzymes, D-dimer, and fibrinogen but no sign of jaundice. Her WBC differential suggested a bacterial infection. Thus, we diagnosed early HELLP syndrome and immediately started conservative treatments. One day after admission, symptoms and laboratory results showed aggravation of the disease. We performed termination, followed by dilation and curettage for retained placenta. Her general condition improved rapidly after the operation. Placen.tal biopsy showed both acute and chronic inflammation. She also had anticardiolipin antibody IgM, and after discharge, she was referred to a rheumatology specialist to address the antiphospho.lipid syndrome issue. Discussion: Although the triggers of HELLP syndrome are unclear, a recent inflammatory hypothesis suggests that placenta-derived inflammatory cytokines are involved. In our case, the anti-cardiolipin antibody may have triggered microangiopathy of the placenta. Our analysis of published HELLP cases revealed that, apart from the three diagnostic criteria, the most common abnormal laboratory finding was antiphospholipid antibodies. Therefore, despite its rarity, if a sign of inflammation is present in a patient, it is important to consider HELLP syndrome regardless of gestational age","PeriodicalId":11030,"journal":{"name":"Current Women s Health Reviews","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136358099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Intimate domestic violence causes psychological consequences in pregnancy and maternal competency. We aimed to assess the effect of domestic violence on mental health and maternal competency with the moderating role of mother-infant attachment behavior. Method: This prospective longitudinal study was conducted on 254 primiparous mothers in the third trimester of pregnancy referring to selected health centers in Qazvin province, Iran. Data collection tools were questionnaires. Data were analyzed by SPSS and Smart Partial Lease Square3 software. Results: The results of the structural equations model showed that domestic violence has a positive and significant effect on mental health disorders (β = 0.87). Mental health disorder has a negative and significant effect on parental acceptance (β = -0.55). Domestic violence has a negative and significant effect on mother-infant attachment behavior (β = -0.83), also mother-infant attachment behavior is a moderator of the relationship between pregnancy violence and maternal competency (T-value = 3.17). Conclusion: The results revealed that domestic violence during pregnancy affects the mental health of pregnant mothers and maternal competency and mother-infant attachment behavior moderates this relationship. Therefore, it is recommended that mothers facing domestic violence be identified and receive psychological support and counseling, and also improve maternal competence and mother-infant attachment behavior in mothers exposed to violence.
{"title":"Predictor Role of Intimate Domestic Violence During Pregnancy and Mental Health in Maternal Competency with Moderating Role of Mother-infant Attachment: A Structural Equation Model","authors":"Faeze Ansarifar, Mitra Rahimzadeh, Maryam Keshavarz, Touran Bahrami Babaheidari, Sara Esmaelzadeh Saeieh","doi":"10.2174/0115734048259773230920104420","DOIUrl":"https://doi.org/10.2174/0115734048259773230920104420","url":null,"abstract":"Introduction: Intimate domestic violence causes psychological consequences in pregnancy and maternal competency. We aimed to assess the effect of domestic violence on mental health and maternal competency with the moderating role of mother-infant attachment behavior. Method: This prospective longitudinal study was conducted on 254 primiparous mothers in the third trimester of pregnancy referring to selected health centers in Qazvin province, Iran. Data collection tools were questionnaires. Data were analyzed by SPSS and Smart Partial Lease Square3 software. Results: The results of the structural equations model showed that domestic violence has a positive and significant effect on mental health disorders (β = 0.87). Mental health disorder has a negative and significant effect on parental acceptance (β = -0.55). Domestic violence has a negative and significant effect on mother-infant attachment behavior (β = -0.83), also mother-infant attachment behavior is a moderator of the relationship between pregnancy violence and maternal competency (T-value = 3.17). Conclusion: The results revealed that domestic violence during pregnancy affects the mental health of pregnant mothers and maternal competency and mother-infant attachment behavior moderates this relationship. Therefore, it is recommended that mothers facing domestic violence be identified and receive psychological support and counseling, and also improve maternal competence and mother-infant attachment behavior in mothers exposed to violence.","PeriodicalId":11030,"journal":{"name":"Current Women s Health Reviews","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135147114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Mayer-Rokitansky-Kuster-Hauser Syndrome is a reproductive system disorder that occurs due to failure in the development of the Müllerian ducts. This disorder is characterized by the absence of the uterus and upper part of the vagina. MRKH syndrome is divided into type I and type II where type II is accompanied by non-gynecological disorders. The most common non-gynecological disorder is renal abnormality. Objectives: This study aims to describe one of the rare clinical manifestations of type II MRKH syndrome. Case Presentation: We reported a case of a sexually inactive woman in her early 20s presenting with primary amenorrhea. The patient had normal secondary female sexual characteristics. In the examination, we found the patient had vaginal agenesis, uterine dysgenesis, normal ovaries, normal right kidney, and left ectopic kidney located in the lower abdomen. Laparoscopic Davydov procedure was done to create a neovagina. Discussion: In our case, the patient was diagnosed with MRKH Syndrome, a syndrome of abnormal uterine and vaginal formation with normal ovarian function. The presence of ectopic kidney in the patient showed the MRKH Syndrome type II, which required comprehensive management. The patient was treated with Davydov procedure, which is a simple, fast and safest surgical procedure in managing MRKH syndrome. Conclusion: A thorough examination is needed in MRKH patients to find other possible non- gynecological disorders, such as renal, vertebral, and hearing disorders, in order to carry out comprehensive management.
{"title":"Ectopic Kidney as a Clinical Manifestation of Type II MRKH Syndrome Patient: A Case Report","authors":"Alfa Putri Meutia, Anggrainy Dwifitriana Kouwagam, Fernandi Moegni, Suskhan Djusad, Surahman Hakim, Tyas Priyatini, Gita Nurul Hidayah, Budi Iman Santoso","doi":"10.2174/0115734048256830230922092500","DOIUrl":"https://doi.org/10.2174/0115734048256830230922092500","url":null,"abstract":"Introduction: Mayer-Rokitansky-Kuster-Hauser Syndrome is a reproductive system disorder that occurs due to failure in the development of the Müllerian ducts. This disorder is characterized by the absence of the uterus and upper part of the vagina. MRKH syndrome is divided into type I and type II where type II is accompanied by non-gynecological disorders. The most common non-gynecological disorder is renal abnormality. Objectives: This study aims to describe one of the rare clinical manifestations of type II MRKH syndrome. Case Presentation: We reported a case of a sexually inactive woman in her early 20s presenting with primary amenorrhea. The patient had normal secondary female sexual characteristics. In the examination, we found the patient had vaginal agenesis, uterine dysgenesis, normal ovaries, normal right kidney, and left ectopic kidney located in the lower abdomen. Laparoscopic Davydov procedure was done to create a neovagina. Discussion: In our case, the patient was diagnosed with MRKH Syndrome, a syndrome of abnormal uterine and vaginal formation with normal ovarian function. The presence of ectopic kidney in the patient showed the MRKH Syndrome type II, which required comprehensive management. The patient was treated with Davydov procedure, which is a simple, fast and safest surgical procedure in managing MRKH syndrome. Conclusion: A thorough examination is needed in MRKH patients to find other possible non- gynecological disorders, such as renal, vertebral, and hearing disorders, in order to carry out comprehensive management.","PeriodicalId":11030,"journal":{"name":"Current Women s Health Reviews","volume":"243 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134944911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background:: Vaginal examination is widely recognized as the most common method for monitoring labor progress. However, researchers are currently exploring alternative methods, which are potentially less invasive or aggressive, to assess labor progress. background: Vaginal examination is the most common method of monitoring labor progress and alternative and less aggressive methods for evaluating labor and labor progress are under consideration. Objective:: This study aimed to assess the correlation between the length of the xiphoid to the fundus and the cervical dilation in the active phase of labor. Methods:: This cross-sectional study was conducted on 180 pregnant women in Varamin, Iran. The participants were recruited using convenience sampling. Data were collected using a researcher- made questionnaire that included specific items regarding demographic characteristics, health status, and a checklist to record the results of examinations and labor progress. The collected data were analyzed using descriptive statistics, correlation tests, and multiple linear regression with SPSS 22 software. The significance level was considered to be p <0.05. method: : This cross-sectional study was conducted on 180 pregnant women in Varamin, Iran. Sampling was done by available method. Data were collected using a researcher-made questionnaire containing demographic characteristics, health status, examination form, and delivery progress and meter. The results were analyzed by descriptive statistics, correlation and multiple linear regression with SPSS 22 software. Significance level was considered p &amp;lt;0.05. Results:: A total of 174 eligible women participated in the study, with a mean age of 25.90 ± 4.56 years (mean±SD) and a mean gestational age of 39.71 ± 1.03 weeks. There was a significant negative correlation between the length of the xiphoid to the fundus and cervical dilatation (p = 0.0001, r = -0.568). Conclusions:: The study revealed a significant negative correlation between the length of the xiphoid to the fundus and the cervical dilation. Therefore, the xiphoid to fundus measurement can serve as an alternative and complementary examination in cases that need frequent vaginal examinations. conclusion: There was a significant inverse correlation between the length of xiphoid to fundus and the cervical dilation. Therefore, given this size during the labor and delivery phases, it can be used as a non-invasive method of assessing labor and delivery progress.
{"title":"The Length of Xiphoid to Fundus as a Measure of Labor Progress: A Cross-sectional Study","authors":"Farzaneh Rashidi Fakari, masoumeh simbar, Hamideh Torkian Demneh, Fahimeh Rashidi Fakari, Zahra Kiani, Abbas Ebadi","doi":"10.2174/0115734048245070230920091849","DOIUrl":"https://doi.org/10.2174/0115734048245070230920091849","url":null,"abstract":"Background:: Vaginal examination is widely recognized as the most common method for monitoring labor progress. However, researchers are currently exploring alternative methods, which are potentially less invasive or aggressive, to assess labor progress. background: Vaginal examination is the most common method of monitoring labor progress and alternative and less aggressive methods for evaluating labor and labor progress are under consideration. Objective:: This study aimed to assess the correlation between the length of the xiphoid to the fundus and the cervical dilation in the active phase of labor. Methods:: This cross-sectional study was conducted on 180 pregnant women in Varamin, Iran. The participants were recruited using convenience sampling. Data were collected using a researcher- made questionnaire that included specific items regarding demographic characteristics, health status, and a checklist to record the results of examinations and labor progress. The collected data were analyzed using descriptive statistics, correlation tests, and multiple linear regression with SPSS 22 software. The significance level was considered to be p <0.05. method: : This cross-sectional study was conducted on 180 pregnant women in Varamin, Iran. Sampling was done by available method. Data were collected using a researcher-made questionnaire containing demographic characteristics, health status, examination form, and delivery progress and meter. The results were analyzed by descriptive statistics, correlation and multiple linear regression with SPSS 22 software. Significance level was considered p &amp;amp;lt;0.05. Results:: A total of 174 eligible women participated in the study, with a mean age of 25.90 ± 4.56 years (mean±SD) and a mean gestational age of 39.71 ± 1.03 weeks. There was a significant negative correlation between the length of the xiphoid to the fundus and cervical dilatation (p = 0.0001, r = -0.568). Conclusions:: The study revealed a significant negative correlation between the length of the xiphoid to the fundus and the cervical dilation. Therefore, the xiphoid to fundus measurement can serve as an alternative and complementary examination in cases that need frequent vaginal examinations. conclusion: There was a significant inverse correlation between the length of xiphoid to fundus and the cervical dilation. Therefore, given this size during the labor and delivery phases, it can be used as a non-invasive method of assessing labor and delivery progress.","PeriodicalId":11030,"journal":{"name":"Current Women s Health Reviews","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135546671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-05DOI: 10.2174/0115734048255407230920072719
Radhouane Achour, Hiba Mkadmi, Rim Ben Hmid
Background: About 70% of gynecological consultations for women in perimenopause are due to metrorrhagia. In most cases, they are only the witness of hormonal disturbances resulting from a luteal deficiency. Transvaginal ultrasound is the first innocuous and available additional examination that is requested as part of an etiological assessment. Objective: Our study aims to evaluate the contribution of ultrasonography in perimenopausal metrorrhagia and investigate possible clinical-ultrasound correlation. Methods: This analytical descriptive study was carried out on 50 treated for perimenopausal metrorrhagia in the emergency department of the Tunis Maternity and Neonatology Center for four months (November 1, 2017, to February 28, 2018). We included in our study patients who were not yet postmenopausal who were ≥ 45 years of age, and who sought care for breakthrough bleeding. All patients in our study initially underwent endovaginal ultrasonography, sometimes coupled with suprapubic ultrasonography. Results: The mean age of our patients was 46.3 years. Pelvic ultrasonography revealed an enlarged uterus in 16 patients (32%), with 14 of them having fibromatous uteri measuring between 3 to 10 centimeters. The findings indicate no significant correlation between ultrasound results and bleeding abundance (P = 0.321), pelvic pain (P = 0.108), and general condition (P = 0.437). Conclusion: Endovaginal pelvic ultrasonography is a quick, painless test and is the first test to be done first in an emergency department with perimenopausal vaginal bleeding. The correlation between clinical and ultrasound findings is highly random, making it impossible to assume a well-- coded diagnostic and therapeutic presumption.
{"title":"Contribution of Pelvic Ultrasonography in Perimenopausal Abnormal Uterine Bleeding","authors":"Radhouane Achour, Hiba Mkadmi, Rim Ben Hmid","doi":"10.2174/0115734048255407230920072719","DOIUrl":"https://doi.org/10.2174/0115734048255407230920072719","url":null,"abstract":"Background: About 70% of gynecological consultations for women in perimenopause are due to metrorrhagia. In most cases, they are only the witness of hormonal disturbances resulting from a luteal deficiency. Transvaginal ultrasound is the first innocuous and available additional examination that is requested as part of an etiological assessment. Objective: Our study aims to evaluate the contribution of ultrasonography in perimenopausal metrorrhagia and investigate possible clinical-ultrasound correlation. Methods: This analytical descriptive study was carried out on 50 treated for perimenopausal metrorrhagia in the emergency department of the Tunis Maternity and Neonatology Center for four months (November 1, 2017, to February 28, 2018). We included in our study patients who were not yet postmenopausal who were ≥ 45 years of age, and who sought care for breakthrough bleeding. All patients in our study initially underwent endovaginal ultrasonography, sometimes coupled with suprapubic ultrasonography. Results: The mean age of our patients was 46.3 years. Pelvic ultrasonography revealed an enlarged uterus in 16 patients (32%), with 14 of them having fibromatous uteri measuring between 3 to 10 centimeters. The findings indicate no significant correlation between ultrasound results and bleeding abundance (P = 0.321), pelvic pain (P = 0.108), and general condition (P = 0.437). Conclusion: Endovaginal pelvic ultrasonography is a quick, painless test and is the first test to be done first in an emergency department with perimenopausal vaginal bleeding. The correlation between clinical and ultrasound findings is highly random, making it impossible to assume a well-- coded diagnostic and therapeutic presumption.","PeriodicalId":11030,"journal":{"name":"Current Women s Health Reviews","volume":"85 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135546582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-11DOI: 10.2174/1573404820666230908092540
Parul Pamma, Sricha Singh, Sakshi Sharma
Abstract: This paper provides a synopsis of maternal and fetal thyroid hormone stimulation during pregnancy. Treatment of thyroid illness during pregnancy is critical for avoiding negative maternal and fetal outcomes. Thyroid disorders are frequently asymptomatic and difficult to detect without specialized monitoring programs. Even mild maternal thyroid hormone insufficiency can result in fetal neurodevelopment difficulties. The thyroid is over-stimulated during pregnancy, resulting in alterations in thyroid hormone concentrations. Accurate thyroid function testing during pregnancy is crucial for both initiating thyroid hormone therapy and adjusting thyroid hormone dose in people who are already on thyroid hormone. Trimester-specific intervals are particularly critical during pregnancy, when thyroid insufficiency has been linked to poor obstetric outcomes and neuro-developmental impairments in the fetus. Knowing the natural changes in hormone concentrations that occur throughout pregnancy allows for customized supplementation of iodine when needed.
{"title":"Regulation of Thyroid Hormone: An Important Aspect During Pregnancy","authors":"Parul Pamma, Sricha Singh, Sakshi Sharma","doi":"10.2174/1573404820666230908092540","DOIUrl":"https://doi.org/10.2174/1573404820666230908092540","url":null,"abstract":"Abstract: This paper provides a synopsis of maternal and fetal thyroid hormone stimulation during pregnancy. Treatment of thyroid illness during pregnancy is critical for avoiding negative maternal and fetal outcomes. Thyroid disorders are frequently asymptomatic and difficult to detect without specialized monitoring programs. Even mild maternal thyroid hormone insufficiency can result in fetal neurodevelopment difficulties. The thyroid is over-stimulated during pregnancy, resulting in alterations in thyroid hormone concentrations. Accurate thyroid function testing during pregnancy is crucial for both initiating thyroid hormone therapy and adjusting thyroid hormone dose in people who are already on thyroid hormone. Trimester-specific intervals are particularly critical during pregnancy, when thyroid insufficiency has been linked to poor obstetric outcomes and neuro-developmental impairments in the fetus. Knowing the natural changes in hormone concentrations that occur throughout pregnancy allows for customized supplementation of iodine when needed.","PeriodicalId":11030,"journal":{"name":"Current Women s Health Reviews","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136026989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-06DOI: 10.2174/1573404820666230906091306
Zeena Raad Helmi, Wassan Nori, Muna Abdul Ghani Zghair
Background: Polycystic ovary syndrome (PCOS) is a leading cause of infertility. Insulin resistance is a key element in pathogenesis. The insulin receptor causes phosphorylation of the insulin receptor substrate (IRS); IRS-1 rs1801278G > A polymorphism variant is the most common genetic variant associated with IR and PCOS. Objective: We aimed to examine the frequency of IRS-1 rs1801278G > A polymorphism variant and test its value in evaluating infertile PCOS women. Methods: A case-control study recruited 140 age and body-mass-matched participants in the university hospital, subdivided according to Rotterdam criteria into PCOS cases (70/140) and healthy controls (70/140). We collected demographic data, ultrasonic [antral follicles and endometrial thickness], hormonal [FSH, LH, AMH, E2], and genetic data by polymerase chain reaction for analysis. Result: Wild GG SNP rs1801278 G was meaningfully higher among controls (58.57%, P<0.0001). Mutant AA SNP rs1801278 was significantly higher in PCOS women (37.14%, P-value =0.0001, an odds ratio of 20.50, 95% CI (9.42-28.63) to develop PCOS. Heterogenous GA gene SNP rs1801278 showed a trend of higher frequency in PCOS patients with 44.29%; OR of 3.91, 95% CI (1.37–7.55); P = 0.422. Upon correlating infertility parameters to SNP rs1801278 G>A polymorphism, statistical differences were found with AFC, LH/FSH ratio, and serum testosterone. As for the AMH, E2, and endometrial thickness, they failed to have a statistical value. Conclusion: The significant correlation of genetic polymorphism to infertility parameters among PCOS women opens a new therapeutic and prognostic avenue that helps gynecologists tailor manganate for a better and safer outcome.
背景:多囊卵巢综合征(PCOS)是导致不孕的主要原因。胰岛素抵抗是发病的关键因素。胰岛素受体引起胰岛素受体底物(IRS)的磷酸化;IRS-1 rs1801278G;多态性变异是与IR和PCOS相关的最常见的遗传变异。目的:探讨IRS-1 rs1801278G >多态性变异及其在评价不育性多囊卵巢综合征中的价值。方法:在大学医院招募年龄和体重匹配的140例患者，按鹿特丹标准分为多囊卵巢综合征患者(70/140)和健康对照组(70/140)。我们通过聚合酶链反应收集了人口统计学数据、超声[窦卵泡和子宫内膜厚度]、激素[FSH、LH、AMH、E2]和基因数据进行分析。结果:野生GG SNP rs1801278 G在对照组中显著升高(58.57%，P<0.0001)。突变型AA SNP rs1801278在PCOS女性中显著升高(37.14%，p值=0.0001，优势比为20.50,95% CI(9.42 ~ 28.63))。异质性GA基因SNP rs1801278在PCOS患者中出现频率较高，占44.29%;OR为3.91,95% CI (1.37-7.55);P = 0.422。将不孕参数与SNP rs1801278 G>A多态性相关联，发现与AFC、LH/FSH比值、血清睾酮有统计学差异。AMH、E2、子宫内膜厚度均无统计学意义。结论:多囊卵巢综合征(PCOS)患者遗传多态性与不孕参数的显著相关性为妇科医生定制治疗方案提供了新的治疗和预后途径，以获得更好、更安全的结局。
{"title":"The Value IRS-1 rs1801278G > A Polymorphism Testing in Evaluating Infertile Women with Polycystic Ovarian Syndrome: A Case-control Study","authors":"Zeena Raad Helmi, Wassan Nori, Muna Abdul Ghani Zghair","doi":"10.2174/1573404820666230906091306","DOIUrl":"https://doi.org/10.2174/1573404820666230906091306","url":null,"abstract":"Background: Polycystic ovary syndrome (PCOS) is a leading cause of infertility. Insulin resistance is a key element in pathogenesis. The insulin receptor causes phosphorylation of the insulin receptor substrate (IRS); IRS-1 rs1801278G > A polymorphism variant is the most common genetic variant associated with IR and PCOS. Objective: We aimed to examine the frequency of IRS-1 rs1801278G > A polymorphism variant and test its value in evaluating infertile PCOS women. Methods: A case-control study recruited 140 age and body-mass-matched participants in the university hospital, subdivided according to Rotterdam criteria into PCOS cases (70/140) and healthy controls (70/140). We collected demographic data, ultrasonic [antral follicles and endometrial thickness], hormonal [FSH, LH, AMH, E2], and genetic data by polymerase chain reaction for analysis. Result: Wild GG SNP rs1801278 G was meaningfully higher among controls (58.57%, P<0.0001). Mutant AA SNP rs1801278 was significantly higher in PCOS women (37.14%, P-value =0.0001, an odds ratio of 20.50, 95% CI (9.42-28.63) to develop PCOS. Heterogenous GA gene SNP rs1801278 showed a trend of higher frequency in PCOS patients with 44.29%; OR of 3.91, 95% CI (1.37–7.55); P = 0.422. Upon correlating infertility parameters to SNP rs1801278 G>A polymorphism, statistical differences were found with AFC, LH/FSH ratio, and serum testosterone. As for the AMH, E2, and endometrial thickness, they failed to have a statistical value. Conclusion: The significant correlation of genetic polymorphism to infertility parameters among PCOS women opens a new therapeutic and prognostic avenue that helps gynecologists tailor manganate for a better and safer outcome.","PeriodicalId":11030,"journal":{"name":"Current Women s Health Reviews","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135203930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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