Pub Date : 2024-07-31Epub Date: 2024-07-04DOI: 10.4012/dmj.2024-034
Lulu Cao, Hong Lin, Shuo Wang, Xinxin Zhan, Dong Xiang, Lian Peng, Jianmin Han
The glass infiltration technique was employed for surface modification of zirconia implants in this study. The prepared glass-infiltrated zirconia with low infiltrating temperature showed excellent mechanical properties and enough infiltrating layer. The zirconia substrate was pre-sintered at 1,200°C and the glass infiltration depth reached 400 μm after infiltrating at 1,200°C for 10 h. The infiltrating glass has good wetting ability, thermal expansion match and good chemical compatibility with the zirconia substrate. Indentation fracture toughness and flexural strength of the dense sintered glass-infiltrated zirconia composite are respectively 5.37±0.45 MPa•m1/2 and 841.03±89.31 MPa. Its elasticity modulus is 163.99±7.6 GPa and has about 500 μm infiltrating layer. The glass-infiltrated zirconia can be acid etched to a medium roughness (1.29±0.09 μm) with a flexural strength of 823.65±87.46 MPa, which promotes cell proliferation and has potential for dental implants.
{"title":"Surface modification of dental zirconia implants with a low infiltration temperature glass.","authors":"Lulu Cao, Hong Lin, Shuo Wang, Xinxin Zhan, Dong Xiang, Lian Peng, Jianmin Han","doi":"10.4012/dmj.2024-034","DOIUrl":"10.4012/dmj.2024-034","url":null,"abstract":"<p><p>The glass infiltration technique was employed for surface modification of zirconia implants in this study. The prepared glass-infiltrated zirconia with low infiltrating temperature showed excellent mechanical properties and enough infiltrating layer. The zirconia substrate was pre-sintered at 1,200°C and the glass infiltration depth reached 400 μm after infiltrating at 1,200°C for 10 h. The infiltrating glass has good wetting ability, thermal expansion match and good chemical compatibility with the zirconia substrate. Indentation fracture toughness and flexural strength of the dense sintered glass-infiltrated zirconia composite are respectively 5.37±0.45 MPa•m<sup>1/2</sup> and 841.03±89.31 MPa. Its elasticity modulus is 163.99±7.6 GPa and has about 500 μm infiltrating layer. The glass-infiltrated zirconia can be acid etched to a medium roughness (1.29±0.09 μm) with a flexural strength of 823.65±87.46 MPa, which promotes cell proliferation and has potential for dental implants.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141497380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The surface treatment of glass-ceramic-based materials, namely, lithium disilicate glass (IPS e.max CAD), feldspar porcelain (VITABLOCS Mark II), and a polymer-infiltrated ceramic network (VITA ENAMIC), using aqueous fluoride solutions and their influence on luting agent bonding were investigated. Six experimental aqueous fluoride solutions were applied to these materials, and their effects were assessed by surface topological analysis. The obtained results were compared using non-parametric statistical analyses. Ammonium hydrogen fluoride (AHF) etchant demonstrated the greatest etching effect. Subsequent experiments focused on evaluating different concentrations of the AHF etchant for the bonding pretreatment of glass-ceramic-based materials with a luting agent (PANAVIA V5). AHF, particularly at concentrations above 5 wt%, effectively roughened the surfaces of the materials and improved the bonding performance. Notably, AHF at a concentration of 30 wt% exhibited a more pronounced effect on both etching and bonding capabilities compared to hydrofluoric acid.
{"title":"Chemical etching of CAD-CAM glass-ceramic-based materials using fluoride solutions for bonding pretreatment.","authors":"Yusaku Nishizawa, Yuya Komagata, Yuki Nagamatsu, Tatsuo Kawamoto, Hiroshi Ikeda","doi":"10.4012/dmj.2023-333","DOIUrl":"10.4012/dmj.2023-333","url":null,"abstract":"<p><p>The surface treatment of glass-ceramic-based materials, namely, lithium disilicate glass (IPS e.max CAD), feldspar porcelain (VITABLOCS Mark II), and a polymer-infiltrated ceramic network (VITA ENAMIC), using aqueous fluoride solutions and their influence on luting agent bonding were investigated. Six experimental aqueous fluoride solutions were applied to these materials, and their effects were assessed by surface topological analysis. The obtained results were compared using non-parametric statistical analyses. Ammonium hydrogen fluoride (AHF) etchant demonstrated the greatest etching effect. Subsequent experiments focused on evaluating different concentrations of the AHF etchant for the bonding pretreatment of glass-ceramic-based materials with a luting agent (PANAVIA V5). AHF, particularly at concentrations above 5 wt%, effectively roughened the surfaces of the materials and improved the bonding performance. Notably, AHF at a concentration of 30 wt% exhibited a more pronounced effect on both etching and bonding capabilities compared to hydrofluoric acid.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141199295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-31Epub Date: 2024-06-29DOI: 10.4012/dmj.2023-261
Ana Carolina Soares Diniz, Thais Bordinassi da Silva, Mayenne Rabelo Araujo, José Bauer, Leily Macedo Firoozmand
Laboratory evidence has shown that 45S5 bioglass can help in dental remineralization, so its incorporation into resin-modified glass ionomer cement (RMGIC) has been studied. This randomized clinical trial aimed to determine the efficacy of RMGIC enriched with 10% 45S5 bioglass (RMGIC/45S5) in preventing the progression of moderate caries lesions. Sixty-six permanent molars with moderate caries lesions, were randomly sealed with RMGIC or RMGIC/45S5. After 1, 3-6 months, patients' oral health, material behavior, and caries evolution were evaluated. Chi-square and Fisher's exact test was employed. After one month, the RMGIC showed higher total retention and better clinical performance compared to RMGIC/45S5, both showed a predominance of sealed teeth or without caries progression. After 6 months, no materials retention, quality and caries progression difference was observed for both materials. Short-term clinical follow-up reveals worse retention and quality of RMGIC/45S5, only after 6 months no clinical/microscopic differences are observed between the materials.
{"title":"Sealing moderate caries lesions with bioactive glass-ionomer: A split-mouth clinical trial.","authors":"Ana Carolina Soares Diniz, Thais Bordinassi da Silva, Mayenne Rabelo Araujo, José Bauer, Leily Macedo Firoozmand","doi":"10.4012/dmj.2023-261","DOIUrl":"10.4012/dmj.2023-261","url":null,"abstract":"<p><p>Laboratory evidence has shown that 45S5 bioglass can help in dental remineralization, so its incorporation into resin-modified glass ionomer cement (RMGIC) has been studied. This randomized clinical trial aimed to determine the efficacy of RMGIC enriched with 10% 45S5 bioglass (RMGIC/45S5) in preventing the progression of moderate caries lesions. Sixty-six permanent molars with moderate caries lesions, were randomly sealed with RMGIC or RMGIC/45S5. After 1, 3-6 months, patients' oral health, material behavior, and caries evolution were evaluated. Chi-square and Fisher's exact test was employed. After one month, the RMGIC showed higher total retention and better clinical performance compared to RMGIC/45S5, both showed a predominance of sealed teeth or without caries progression. After 6 months, no materials retention, quality and caries progression difference was observed for both materials. Short-term clinical follow-up reveals worse retention and quality of RMGIC/45S5, only after 6 months no clinical/microscopic differences are observed between the materials.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141466828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study aimed to clarify the fracture resistance of resin abutments built on endodontically treated roots with the remaining coronal teeth via static and cyclic loading tests. Endodontically treated bovine roots, which had a remaining coronal tooth covered with an occupied area for a quarter and half of the circumference at the tensile side or covered the circumference at both the tensile and compressive sides, were fabricated to build up to the resin abutment. Fracture resistance was evaluated via static and cyclic loading tests by applying a load of 30° to the tooth axis. Half of the circumference of the remaining coronal tooth showed a significantly higher static fracture load and survival rate. The remaining coronal tooth on the compressive side improved the dynamic fracture resistance associated with severe fractures. The occupied area and location of the remaining coronal tooth affected the static and dynamic fracture resistances.
{"title":"Influence of remaining coronal tooth morphology with resin abutment and fiber post on static and dynamic fracture resistances.","authors":"Shunsuke Kimura, Hideshi Sekine, Takahiro Kawasaki, Toru Sato, Norio Kasahara","doi":"10.4012/dmj.2023-295","DOIUrl":"10.4012/dmj.2023-295","url":null,"abstract":"<p><p>This study aimed to clarify the fracture resistance of resin abutments built on endodontically treated roots with the remaining coronal teeth via static and cyclic loading tests. Endodontically treated bovine roots, which had a remaining coronal tooth covered with an occupied area for a quarter and half of the circumference at the tensile side or covered the circumference at both the tensile and compressive sides, were fabricated to build up to the resin abutment. Fracture resistance was evaluated via static and cyclic loading tests by applying a load of 30° to the tooth axis. Half of the circumference of the remaining coronal tooth showed a significantly higher static fracture load and survival rate. The remaining coronal tooth on the compressive side improved the dynamic fracture resistance associated with severe fractures. The occupied area and location of the remaining coronal tooth affected the static and dynamic fracture resistances.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study evaluated fracture resistance of monolithic fixed dental prostheses (FDPs) fabricated using different placement strategies of various connector designs in multilayered zirconia disc. Monolithic FDPs were placed in translucent and dentin layers of multilayered zirconia disc and fabricated with V-shaped and U-shaped connector designs gained by sharp and blunt millings. The FDPs were cemented on abutment models made of polymer material, underwent thermal cycles, and loaded to fracture using the universal testing machine. Fracture loads and modes were analyzed using two-way ANOVA, Tukey's post hoc test, and Fisher exact test (p≤0.05). The chosen placement strategy and connector designs gained by different milling procedures in computer-aided design/computer-aided manufacturing technology affect fracture resistance of monolithic FDPs made of multilayered zirconia materials. Placing the connector in translucent layer rather than dentin layer of multilayered zirconia disc and using sharp milling significantly reduces fracture resistance of monolithic multilayered zirconia FDPs.
本研究评估了在多层氧化锆牙盘中使用不同连接体设计的不同放置策略制作的整体固定义齿(FDP)的抗断裂性。在多层氧化锆盘的半透明层和牙本质层中放置了单体固定义齿,并使用尖磨和钝磨获得的 V 形和 U 形连接体设计制作了单体固定义齿。将 FDP 粘接在聚合物材料制成的基台模型上,进行热循环,并使用万能试验机加载至断裂。采用双向方差分析、Tukey 后检验和费雪精确检验(P≤0.05)对断裂载荷和断裂模式进行分析。通过计算机辅助设计/计算机辅助制造技术的不同铣削程序获得的所选植入策略和连接体设计会影响多层氧化锆材料制成的单片 FDP 的抗断裂性。在多层氧化锆牙盘的半透明层而不是牙本质层放置连接体,并使用锐铣,可显著降低整体多层氧化锆 FDP 的抗断裂性。
{"title":"Effect of placement strategies and connector designs in CAD/CAM technology on fracture resistance of multilayered monolithic zirconia fixed dental prostheses: An in vitro study.","authors":"Fahad Bakitian","doi":"10.4012/dmj.2024-018","DOIUrl":"https://doi.org/10.4012/dmj.2024-018","url":null,"abstract":"<p><p>This study evaluated fracture resistance of monolithic fixed dental prostheses (FDPs) fabricated using different placement strategies of various connector designs in multilayered zirconia disc. Monolithic FDPs were placed in translucent and dentin layers of multilayered zirconia disc and fabricated with V-shaped and U-shaped connector designs gained by sharp and blunt millings. The FDPs were cemented on abutment models made of polymer material, underwent thermal cycles, and loaded to fracture using the universal testing machine. Fracture loads and modes were analyzed using two-way ANOVA, Tukey's post hoc test, and Fisher exact test (p≤0.05). The chosen placement strategy and connector designs gained by different milling procedures in computer-aided design/computer-aided manufacturing technology affect fracture resistance of monolithic FDPs made of multilayered zirconia materials. Placing the connector in translucent layer rather than dentin layer of multilayered zirconia disc and using sharp milling significantly reduces fracture resistance of monolithic multilayered zirconia FDPs.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141859265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-31Epub Date: 2024-06-25DOI: 10.4012/dmj.2023-319
Shuichi Yamagata, Takaaki Yamamoto, Yoshiaki Sato, Tsukasa Akasaka, Yasuhiro Yoshida
No effective technique exists for removing adhesive remnants following bracket debonding. We propose that fluorescence imaging using europium ions (Eu3+) offers an effective solution for minimizing iatrogenic enamel damage. This study aimed to assess the impact of different mixing ratios of monomer mixtures on the photoluminescence and flexural properties of a newly developed fluorescent adhesive. Four monomer blends with varying urethane dimethacrylate (UDMA) to triethylene glycol dimethacrylate (TEGDMA) ratios were prepared and polymerized. The blends contained 0.1 wt% of tris(1,3-diphenyl-1,3-propanedionato)(1,10-phenanthroline) Eu(III), [Eu(DBM)3Phen], as the phosphor. Optical measurements and flexural tests were conducted for each resin specimen. The emission spectra exhibited narrow bands corresponding to the 4f-4f transitions of the Eu3+ ions. The photoluminescence properties remained unaffected by the mixing ratio, whereas the mechanical properties tended to improve with higher UDMA content. We conclude that the Eu(DBM)3Phen-containing resin shows promise as a fluorescent orthodontic adhesive that contributes to preserving enamel health.
{"title":"Synthesis and evaluation of fluorescent resins with europium-β-diketonate complex for orthodontic use.","authors":"Shuichi Yamagata, Takaaki Yamamoto, Yoshiaki Sato, Tsukasa Akasaka, Yasuhiro Yoshida","doi":"10.4012/dmj.2023-319","DOIUrl":"10.4012/dmj.2023-319","url":null,"abstract":"<p><p>No effective technique exists for removing adhesive remnants following bracket debonding. We propose that fluorescence imaging using europium ions (Eu<sup>3+</sup>) offers an effective solution for minimizing iatrogenic enamel damage. This study aimed to assess the impact of different mixing ratios of monomer mixtures on the photoluminescence and flexural properties of a newly developed fluorescent adhesive. Four monomer blends with varying urethane dimethacrylate (UDMA) to triethylene glycol dimethacrylate (TEGDMA) ratios were prepared and polymerized. The blends contained 0.1 wt% of tris(1,3-diphenyl-1,3-propanedionato)(1,10-phenanthroline) Eu(III), [Eu(DBM)<sub>3</sub>Phen], as the phosphor. Optical measurements and flexural tests were conducted for each resin specimen. The emission spectra exhibited narrow bands corresponding to the 4f-4f transitions of the Eu<sup>3+</sup> ions. The photoluminescence properties remained unaffected by the mixing ratio, whereas the mechanical properties tended to improve with higher UDMA content. We conclude that the Eu(DBM)<sub>3</sub>Phen-containing resin shows promise as a fluorescent orthodontic adhesive that contributes to preserving enamel health.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141455787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Experimental light-curing pattern resins were fabricated to produce pattern resin materials with adequate dimensional stability. The light-curing pattern resins consisted of poly(n-butyl methacrylate) or poly(iso-butyl methacrylate) (PiBMA) polymers and methacrylate monomers. The physical properties, amount of residual ash after burning, Vickers hardness, flexural strength, and volumetric polymerization shrinkage of each material were determined. The data obtained for the prepared resins were compared with those of a commercially available pattern resin, Palavit G (PG). A lower amount of residual ash was observed for some of the prepared resins than for PG. The Vickers hardness and flexural strength values of all experimental resins were lower than those of PG. The volumetric polymerization shrinkage of all the experimental resins based on PiBMA was lower than that of PG. These results suggest that acrylic light-curing resin materials based on PiBMA may be useful for patterning and indexing during soldering.
{"title":"Physical properties of experimental light-curing pattern resins based on poly (n-butyl methacrylate) or poly(iso-butyl methacrylate).","authors":"Akihiko Kadokawa, Sadaaki Murahara, Hiroshi Kono, Asami Uenodan, Asako Fuchida, Fumiko Nishio, Hiroyuki Minami","doi":"10.4012/dmj.2023-278","DOIUrl":"10.4012/dmj.2023-278","url":null,"abstract":"<p><p>Experimental light-curing pattern resins were fabricated to produce pattern resin materials with adequate dimensional stability. The light-curing pattern resins consisted of poly(n-butyl methacrylate) or poly(iso-butyl methacrylate) (PiBMA) polymers and methacrylate monomers. The physical properties, amount of residual ash after burning, Vickers hardness, flexural strength, and volumetric polymerization shrinkage of each material were determined. The data obtained for the prepared resins were compared with those of a commercially available pattern resin, Palavit G (PG). A lower amount of residual ash was observed for some of the prepared resins than for PG. The Vickers hardness and flexural strength values of all experimental resins were lower than those of PG. The volumetric polymerization shrinkage of all the experimental resins based on PiBMA was lower than that of PG. These results suggest that acrylic light-curing resin materials based on PiBMA may be useful for patterning and indexing during soldering.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-31Epub Date: 2024-06-01DOI: 10.4012/dmj.2023-312
Ji-Hun Youm, Il Jun Jeong, Jae-Sung Kwon, Bum-Soon Lim, Myung-Hwan Oh, Kwang-Mahn Kim
This study aimed to propose the measurement methods for resin composite translucency using four shades of resin composite and four spectrophotometers. Four methods were used for measuring translucency: (A) color measurement using reflectance mode, (B) visible light spectrum measurement using reflectance mode, (C) color measurement using transmittance mode, (D) visible light spectrum measurement using transmittance mode. Although there was a significant difference among the results of the translucency measuring methods, the same tendency was observed for translucency parameters obtained using each spectrophotometer. Therefore, the four methods can potentially be used as translucency measuring methods for resin composite.
{"title":"The optical property measuring methods for resin composite using multiple spectrophotometers.","authors":"Ji-Hun Youm, Il Jun Jeong, Jae-Sung Kwon, Bum-Soon Lim, Myung-Hwan Oh, Kwang-Mahn Kim","doi":"10.4012/dmj.2023-312","DOIUrl":"10.4012/dmj.2023-312","url":null,"abstract":"<p><p>This study aimed to propose the measurement methods for resin composite translucency using four shades of resin composite and four spectrophotometers. Four methods were used for measuring translucency: (A) color measurement using reflectance mode, (B) visible light spectrum measurement using reflectance mode, (C) color measurement using transmittance mode, (D) visible light spectrum measurement using transmittance mode. Although there was a significant difference among the results of the translucency measuring methods, the same tendency was observed for translucency parameters obtained using each spectrophotometer. Therefore, the four methods can potentially be used as translucency measuring methods for resin composite.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141199327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-31Epub Date: 2024-07-04DOI: 10.4012/dmj.2023-286
José Alfredo Facio Umaña, Roberto Beltran Del Rio Parra, Raúl Uriel Medina Martínez, Nadia Betancourt Martínez, Pedro Iv González Luna, Javier Morán Martínez
Orthodontic brackets and archwires placed intraorally are subject to corrosion, leading to the release of cytotoxic metal ions. The aim of this study was to determine whether the use of orthodontic NiTi archwires increases systemic Ni levels and cause alterations on the DNA of cells unrelated to the oral environment such as lymphocytes and sperm cells. Human urine, semen and blood samples were collected before (baseline) sham placement of orthodontic archwires and 15 and 30 days after placement. Lymphocytes and sperm cells cells were evaluated by comet assay. Ni concentration levels in urine increased significantly between baseline and 15 days (p<0.01) and 15 and 30 days of exposure (p<0.01). Progressive decrease in sperm viability and motility was observed between the sampling periods. Lymphocytes and sperm cells showed DNA fragmentation. The increase in systemic concentration of nickel induced structural damage in the DNA of lymphocytes and human sperm cells.
口腔内放置的正畸托槽和弓丝会受到腐蚀,从而释放出具有细胞毒性的金属离子。本研究的目的是确定使用正畸镍钛弓丝是否会增加全身的镍含量,并对淋巴细胞和精子细胞等与口腔环境无关的细胞的 DNA 造成改变。在假性安装正畸弓丝前(基线)、安装后 15 天和 30 天收集人体尿液、精液和血液样本。通过彗星试验对淋巴细胞和精子细胞进行了评估。尿液中的镍浓度水平在基线和 15 天之间明显增加(p
{"title":"DNA fragmentation of lymphocytes and sperm cells induced by nickel released from orthodontic archwires: A preliminary study.","authors":"José Alfredo Facio Umaña, Roberto Beltran Del Rio Parra, Raúl Uriel Medina Martínez, Nadia Betancourt Martínez, Pedro Iv González Luna, Javier Morán Martínez","doi":"10.4012/dmj.2023-286","DOIUrl":"10.4012/dmj.2023-286","url":null,"abstract":"<p><p>Orthodontic brackets and archwires placed intraorally are subject to corrosion, leading to the release of cytotoxic metal ions. The aim of this study was to determine whether the use of orthodontic NiTi archwires increases systemic Ni levels and cause alterations on the DNA of cells unrelated to the oral environment such as lymphocytes and sperm cells. Human urine, semen and blood samples were collected before (baseline) sham placement of orthodontic archwires and 15 and 30 days after placement. Lymphocytes and sperm cells cells were evaluated by comet assay. Ni concentration levels in urine increased significantly between baseline and 15 days (p<0.01) and 15 and 30 days of exposure (p<0.01). Progressive decrease in sperm viability and motility was observed between the sampling periods. Lymphocytes and sperm cells showed DNA fragmentation. The increase in systemic concentration of nickel induced structural damage in the DNA of lymphocytes and human sperm cells.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141497378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study aimed to compare the effect of silver diamine fluoride (SDF) and fluoride varnish (NaF) on the Vickers microhardness (VHN) of enamel and dentin after radiotherapy and pH-cycling. Human premolars were cut longitudinally, embedded and serially polished. The VHN of enamel/dentin and irradiated enamel/dentin were evaluated. The irradiated specimens were treated with either NaF or SDF, subjected to pH-cycling then VHN test for 4 days. Consequently, they were subjected to energy-dispersive X-ray (EDX) analysis. Radiation adversely affect enamel VHN (p<0.05), whereas dentin VHN was not affected (p>0.05). After pH-cycling, a significant decrease in dentin VHN was observed on day 2 for all groups, whereas enamel VHN was significantly decreased in the control group on day 4. SDF-treated enamel demonstrated higher VHN than that of NaF on day 3. Caries prevention effect of SDF and NaF were observed on enamel, where SDF was proved to be superior to NaF.
{"title":"Effects of NaF versus SDF treatment on microhardness of artificial radiation caries at cervical and root areas.","authors":"Pipop Saikaew, Karis Katekovit, Anocha Buranarachada, Nattapat Saimala, Anussara Prayongrat, Pornpoj Fuangtharnthip","doi":"10.4012/dmj.2024-032","DOIUrl":"10.4012/dmj.2024-032","url":null,"abstract":"<p><p>This study aimed to compare the effect of silver diamine fluoride (SDF) and fluoride varnish (NaF) on the Vickers microhardness (VHN) of enamel and dentin after radiotherapy and pH-cycling. Human premolars were cut longitudinally, embedded and serially polished. The VHN of enamel/dentin and irradiated enamel/dentin were evaluated. The irradiated specimens were treated with either NaF or SDF, subjected to pH-cycling then VHN test for 4 days. Consequently, they were subjected to energy-dispersive X-ray (EDX) analysis. Radiation adversely affect enamel VHN (p<0.05), whereas dentin VHN was not affected (p>0.05). After pH-cycling, a significant decrease in dentin VHN was observed on day 2 for all groups, whereas enamel VHN was significantly decreased in the control group on day 4. SDF-treated enamel demonstrated higher VHN than that of NaF on day 3. Caries prevention effect of SDF and NaF were observed on enamel, where SDF was proved to be superior to NaF.</p>","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141455786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}