Dental materials journal最新文献

This bibliometric analysis is aimed at identifying and analyzing the articles on the dental applications of enamel matrix derivatives (EMDs). Data were obtained from the Web of Science and analyzed using the Bibliometrix program. Publications indexed in SCI-Expanded and ESCI under 'Dentistry, Oral Surgery, and Medicine' were included, while non-English and non-article/review types were excluded. A total of 854 articles were reviewed, focusing on: article performance, word analysis, co-citation, and thematic analysis. Data analysis showed a growing number of publications in this field over time. Sculean A emerged as the leading researcher, while the Journal of Clinical Periodontology was the most influential journal. Recent research trends primarily focused on periodontal regeneration. Finally, thematic analysis revealed two motor themes, four niche themes, two emerging/declining themes, and three basic theme clusters. This bibliometric analysis highlights the increasing interest and the emergence of new research trends in the field of EMDs in dentistry.

Oral candidiasis is a significant health concern, especially for elderly individuals. The present study examined chitosan as a potential antimicrobial dental material for Candida albicans treatment. Four types of chitosan products purified from Chionoecetes opilio and Decapodiformes, with varying weight average molecular weight and degree of deacetylation (DAC) were used. Antimicrobial activity was assessed with fungal viability assays, culture turbidity measurements, and live/dead cell staining, while mechanism of action was determined by examining extracellular adenosine triphosphate (ATP) level, reactive oxygen species (ROS) production, and gene expression changes. All examined products exhibited antimicrobial activity, with Decapodiformes-derived chitosan showing better efficacy. Greater molecular weight was correlated with immediate effects and higher DAC with sustained activity. Chitosan treatment increased extracellular ATP and ROS levels, and suppression of genes involved in mitochondrial biosynthesis and drug resistance. These findings suggest potential use of chitosan as an antimicrobial agent in dental materials for oral candidiasis prevention and treatment.

Nutrients diffusion through barrier membranes used in guided bone regeneration is much theorized but few data are available so far. In this study, direct measurement of the water and solute permeability coefficients of five commercial barrier membranes was performed and the results were correlated with scanning electron microscopy findings. First the hydraulic permeability was addressed in short (3 h) and extended periods (3 weeks) assays, then the membranes were further investigated for diffusion of selected solutes (glucose and NaCl). The collagen membrane had the highest initial water permeability, 10 times greater than the polylactide one, and 500 times greater than the expanded-PTFE one, all of which decreased significantly over the 3-weeks test period, whereas dense-PTFE membranes were both found impermeable, the results being positively correlated with solute permeability coefficients and convergent with the SEM findings.

The study evaluated the effects of postoperative bleaching with HP and CP on microtensile bond strength (μTBS) and nanoleakage of composite restorations using total-/self-etch protocols. Sixty incisors with Black V cavities were restored using a multimode adhesive in total-/self-etch mode and resin composite. Samples were divided into five groups: control, CP×2, CP×5, HP×2, HP×5. After bleaching, 1×1×8 mm composite blocks (n=10) were tested for μTBS, and failure types were assessed. Two samples per group were analyzed for nanoleakage via scanning electron microscope (SEM). Two-way analysis of variance, Bonferroni correction, and stepwise linear regression were applied. CP×5 and HP×5 groups exhibited significantly reduced μTBS compared to control, and the self-etch protocol resulted in lower values regardless of bleaching method. Regression analysis confirmed significant effects of adhesive (total-etch) and bleaching (CP×5, HP×5). A significant relationship was found between failure modes and bleaching methods for each adhesive protocol, with adhesive failures being the most frequent. SEM revealed nanoleakage in all groups.

This study aimed to determine the influence of air abrasion on the shear bond strength (SBS) of universal adhesives when using different abrasive powders. The AquaCare Twin served as the injection device. The prepared bovine dentin specimens were air- abraded with alumina particles or bioactive glass before applying the universal adhesive (All Bond Universal, Clearfil Universal Bond Quick ER, or Scotchbond Universal Plus Adhesive). The resin composite-bonded specimens were stored in distilled water at 37°C for 24 h before measuring the SBS. The roughness and free energy of the adherent surfaces were measured, followed by scanning electron microscopy (SEM) and SEM/Energy dispersive X-ray analyses. Dentin pre-treatment and the adhesives used significantly affected the SBS values (p<0.001). Significant interactions were observed between pre-treatment conditions and the adhesive system (p<0.001). The bond strengths of universal adhesive depended on the surface properties of the dentin and the powder used.

This study evaluated the cytotoxicity of various composite resins (CRs) on human periodontal ligament (PDL) cells, focusing on material composition and ion release. Eight CRs of three sizes were tested: Large (6.5 mm diameter, 1.5 mm thickness), Medium (2.0 mm diameter, 1.5 mm thickness), and Small (1.5 mm diameter, 0.5 mm thickness). Cytotoxicity was assessed by cell counting on immortalized and primary PDL cell lines. CRs containing Surface pre-reacted glass ionomer filler showed significant size-dependent cytotoxicity, with larger specimens exhibiting higher ion release of BO₃^3-, Sr²⁺, SiO₃^2-, and F^-, which correlated with adverse effects. Smaller specimens with reduced ion release had lower cytotoxicity and sometimes promoted cell proliferation. These results emphasize the role of material composition and ion release in the biocompatibility of CR for subgingival restorations. Optimizing specimen size and controlling ion release could mitigate adverse effects, suggesting further research to balance therapeutic benefits and risks in periodontal tissues.

The encapsulation and the release of ascorbate-2-phosphate (AsAP) and β-glycerophosphate (β-GP) in microspheres (MSs) consist of poly(lactide-co-glycolide) (PLGA) and poly(ε-caploractone) (PCL) with octacalcium phosphate (OCP) were studied. AsAP-loaded PLGA/PCL (50:50) MSs (AsAP-MSs) were prepared using a water-in-oil-in-water emulsion evaporation. β-GP-loaded PLGA/PCL MSs (β-GP-MS) were prepared similarly while β-GP was directly added in oil. The oil phase dichloromethane was evaporated producing pores in MSs. MSs were characterized by physical techniques such as Fourier transform infrared spectroscopy (FTIR). The drug encapsulation efficiency (E.E.) was evaluated by spectrophotometer after water-extracting. The drug releases into supernatant were analyzed after incubating in 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid (HEPES)-NaCl buffer at 37°C for 36 days. E.E. was 89% for AsAP and 67% for β-GP, and AsAp was released immediately while β-GP was continuously released. OCP was hydrolyzed to hydroxyapatite, affecting β-GP release. PLGA/PCL MSc with OCP may be effective for the release of osteogenic factors.

In this innovative study, the ferrule design for endocrowns was compared with a new preparation design with tetra-corner retention grooves at each corner of the access cavity, and the 3D finite element method was used for analysis. Resin nanoceramic (RNC), lithium disilicate glass-ceramic (LDS), polyetheretherketone (PEEK), and polymer-infiltrated ceramic network (PICN) materials were investigated. The new design significantly reduced the stress for LDS and PICN in axial and oblique loadings. On remaining tooth tissues, the tetra-corner retention groove design increased the stress peak for RNC and PEEK compared to the ferrule, while it decreased the stress for LDS and PICN under both forces. It was concluded that the new, modified preparation design could be used as an alternative design to the ferrule.

This study examined the effects of ultra-long hydroxyapatite nanofibers on bisphenol A-glycidyl methacrylate (Bis-GMA)/ urethane dimethacrylate (TEGDMA) dental resin. Experimental composites incorporating 2 wt% to 8 wt% ultra-long hydroxyapatite nanofibers were assessed for their mechanical properties, ion release behavior, and cytotoxicity. The results indicated that the addition of 2 wt% or 4 wt% nanofibers significantly enhanced the mechanical attributes of the composite materials, whereas higher concentrations led to a deterioration in performance. Moreover, these materials demonstrated the release of Ca²⁺ and PO₄^3- ions in both artificial saliva and lactic acid solutions, evidencing satisfactory cytocompatibility. The acquired data were subjected to statistical analysis via analysis of variance (ANOVA), with differences deemed statistically significant at p<0.05. Therefore, ultra-long hydroxyapatite nanofiber composites emerge as a promising innovative option for dental restoration.

Light-cured shade-characterizing agents are used for composite materials to mimic natural tooth color. Tooth-brushing abrasion tests were conducted to investigate the durability of the agents. Computer-aided design/computer-aided manufacturing (CAD-CAM) composite-resin blocks were used, and the surface was polished with #2000 SiC paper before the agent application. Four different shade agents were applied to the blocks, treated the surface no/with sandblasting. Tooth-brush abrasion tests were carried out for 20,000 cycles at a frequency of 2 Hz with 2.0 N of brushing force. Surface roughness, gloss, contact angle, and color differences were obtained. The number of repetitions was set to ten. It was found that a significant increase in surface roughness and decreases in gloss and water contact angle by tooth brushing tests were clarified. However, the color change by brushing was not significantly large. The color difference before and after applying agents and surface roughness differed in the shade differences in the agents.