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Effective approach to a synthesis of fluorine-containing 4-acylamino-4,5,6,7-tetrahydrobenzisoxazoles 合成含氟4-酰基氨基-4,5,6,7-四氢苯并异恶唑的有效方法
Pub Date : 2020-01-05 DOI: 10.29235/1561-8323-2019-63-6-716-720
T. S. Khlebnicova, Yu. A. Piven, I. Gerus, A. Sorochinsky, F. Lakhvich
On the example of synthesis of 4-acetylamino-3-fluoroalkyl(aryl)-4,5,6,7-tetrahydro-1,2-benzisoxazoles, the effective approach to a synthesis of novel 4-acylamino-4,5,6,7-tetrahydro-1,2-benzisoxazoles is proposed. 3-Fluoroalkyl(aryl)- 6,7-dihydro-1,2-benzisoxazol-4-ones were reduced by a sodium borohydride in isopropanol to obtain 3-fluoroalkyl(aryl)- 4,5,6,7-tetrahydro-1,2-benzisoxazol-4-ols that in the conditions of the Ritter reaction (acetonitrile, acetic acid, sulfuric acid) gave target 4-acylamino derivatives with 80–94 % yields.
以4-乙酰氨基-3-氟烷基(芳基)-4,5,6,7-四氢-1,2-苯并异恶唑的合成为例,提出了合成新型4-乙酰氨基-4,5,6,7-四氢-1,2-苯并异恶唑的有效方法。在异丙醇中用硼氢化钠还原3-氟烷基(芳基)- 6,7-二氢-1,2-苯并恶唑-4-酮,得到3-氟烷基(芳基)- 4,5,6,7-四氢-1,2-苯并恶唑-4-醇,并在Ritter反应(乙腈、乙酸、硫酸)条件下得到目标4-酰基胺衍生物,产率为80 - 94%。
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引用次数: 0
On the possibility of evaluative prediction of the extraction of organic substances of complex structure using the method of group increments 基团增量法评价预测复杂结构有机物提取的可能性
Pub Date : 2020-01-05 DOI: 10.29235/1561-8323-2019-63-6-704-715
M. Zayats, S. Leschev, A. U. Zaidzel
The distribution of pesticides of different classes (amides, anilinopyrimidines, benzene derivatives, benzoylphenylureas, benzenesulfonates, hydrazides, dinitroanilines, carbamates, pyretroids, pyrimidines, tetrazines, triazoles, pheny lureas, organophosphorus compounds, esters of carboxylic acids) was studied at 20 ± 1 °C in the extraction systems of hexane–water, hexane–acetonitrile, hexane– acetonitrile and water mixture that are most often used in analytical chemistry of pesticides. The distribution constants P of pesticides and the increments of logarithms of the distribution constants If of their functional groups between the hydrocarbon and polar phases are calculated. Two main methods for evaluative prediction of lg P of pesticides are proposed and approved – substitutive method based on the calculation of lg P by replacing the substituents in the base molecule and the method of absolute addition of increments. The possibilities of the both methods are illustrated. The reasons for the deviations of the experimental values from the calculated ones are discussed. The influence of the nature and composition of the polar phase on the magnitudes of the observed deviations is estimated. In particular, they decrease dramatically with an increase in the acetonitrile content in the polar phase. Averaged values of correction to the calculated values of lg P are introduced. In most cases, they allow predicting lg P of pesticides with a deviation of not more than 0.5–1.0 from the calculated one.
在20±1℃条件下,研究了农药分析化学中常用的正己烷-水、正己烷-乙腈、正己烷-乙腈和水的萃取体系中不同类别(酰胺类、苯胺类、苯衍生物、苯甲酰苯基脲类、苯磺酸类、肼类、二硝基苯胺类、氨基甲酸酯类、吡咯烷类、嘧啶类、四嗪类、三唑类、苯脲类、有机磷类化合物、羧酸酯类)农药的分布。计算了农药的分布常数P及其官能团在烃相和极性相之间的分布常数If的对数增量。提出并批准了两种主要的评价预测方法:通过取代基分子中取代基来计算农药的lg P的取代法和增量的绝对加法法。说明了这两种方法的可能性。讨论了实验值与计算值偏差的原因。估计了极相的性质和组成对观测到的偏差大小的影响。特别是,它们随着极性相中乙腈含量的增加而急剧减少。介绍了lg P计算值的平均校正值。在大多数情况下,它们允许预测农药的lg P与计算值的偏差不超过0.5-1.0。
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引用次数: 0
Method for calculation of radiative heat transfer in beds of spherical particles 球形颗粒床中辐射传热的计算方法
Pub Date : 2020-01-04 DOI: 10.29235/1561-8323-2019-63-6-680-688
А.И. Малиновский
A new technique for implementing external (particle-to-wall) and particle-to-particle radiative heat transfer in discrete elements method (DEM) simulations is proposed. It is based on the idea that an expected view factor value depends on relevant local bed parameters (distance between particles, particle radius ratio, and local bed porosity). Calculation of average view factors via the formula requires considerably less computational effort than direct in situ integration, when this happens a reasonable average value and an overall accuracy comparable to direct calculation are provided. Both mono- and polydisperse mixtures of spherical opaque particles were considered. It was shown that using nondimensional parameters, a simple general dependence for an external radiative heat flux may be introduced. Exponential and linear fits were proposed for estimating the particle-particle radiative heat flux. The generalization of the obtained formulas for various bed porosities is proposed. The distribution of cumulative transferred heat flux across the particles up to a certain distance was found, and the recommendations regarding the choice of that parameter to achieve a desired accuracy were formulated. Also, the method to account for the particle emissivity was proposed on the basis of the empirical dependence between emissivity and radiative heat flux in porous materials. The proposed method satisfies all the requirements to become a standard implementation of radiative heat transfer calculation in DEM.
提出了一种在离散元法(DEM)模拟中实现外(粒子对壁)和粒子对粒子辐射传热的新技术。它基于这样一种思想,即预期的视因子值取决于相关的局部床层参数(颗粒之间的距离、颗粒半径比和局部床层孔隙度)。通过该公式计算平均视点因子比直接就地积分所需的计算量要少得多,当这种情况发生时,可以提供与直接计算相当的合理平均值和总体精度。考虑了单分散和多分散的球形不透明颗粒混合物。结果表明,使用无量纲参数,可以引入外辐射热通量的简单一般依赖关系。采用指数拟合和线性拟合的方法估计粒子-粒子辐射热流密度。对所得公式进行了各种床层孔隙度的推广。发现了在一定距离内粒子间累积传递热通量的分布,并提出了关于选择该参数以达到所需精度的建议。根据多孔材料中粒子发射率与辐射热通量的经验关系,提出了粒子发射率的计算方法。该方法满足了成为DEM中辐射传热计算标准实现的所有要求。
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引用次数: 0
Опорные точки полунепрерывных снизу функций относительно множества липшицевых вогнутых функций 函数下半连续的支点相对于许多粘性凹形函数
Pub Date : 2020-01-04 DOI: 10.29235/1561-8323-2019-63-6-647-653
Валентин Викентьевич Гороховик, А. С. Тыкун
For the functions defined on normed vector spaces, we introduce a new notion of the LC -convexity that generalizes the classical notion of convex functions. A function is called to be LC -convex if it can be represented as the upper envelope of some subset of Lipschitz concave functions. It is proved that the function is LC -convex if and only if it is lower semicontinuous and, in addition, it is bounded from below by a Lipschitz function. As a generalization of a global subdifferential of a classically convex function, we introduce the set of LC -minorants supported to a function at a given point and the set of LC -support points of a function that are then used to derive a criterion for global minimum points and a necessary condition for global maximum points of nonsmooth functions. An important result of the article is to prove that for a LC - convex function, the set of LC -support points is dense in its effective domain. This result extends the well-known Brondsted– Rockafellar theorem on the existence of the sub-differential for classically convex lower semicontinuous functions to a wider class of lower semicontinuous functions and goes back to the one of the most important results of the classical convex analysis – the Bishop–Phelps theorem on the density of support points in the boundary of a closed convex set.
对于赋范向量空间上的函数,我们引入了一个新的LC -凸性的概念,推广了经典凸函数的概念。如果一个函数可以表示为Lipschitz凹函数子集的上包络,则称为LC -凸函数。证明了该函数是LC -凸的当且仅当它是下半连续的,并且由一个Lipschitz函数从下有界。作为经典凸函数的整体子微分的推广,我们引入了函数在给定点处支持的LC -次要点集和函数的LC -支撑点集,然后利用它们推导出非光滑函数的整体极小点的判据和全局极大点的必要条件。本文的一个重要结果是证明了对于LC -凸函数,LC -支撑点集合在其有效区域内是密集的。这一结果将著名的关于经典凸下半连续函数的子微分存在性的Brondsted - Rockafellar定理推广到更广泛的下半连续函数,并回溯到经典凸分析中最重要的结果之一——关于闭凸集边界支点密度的Bishop-Phelps定理。
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引用次数: 3
Solvability criterion of the control problem of an asynchronous spectrum of linear almost periodic systems with the trivial averaging of the coefficient matrix 具有系数矩阵平凡平均的线性概周期系统异步谱控制问题的可解性判据
Pub Date : 2020-01-04 DOI: 10.29235/1561-8323-2019-63-6-654-661
A. Demenchuk
A linear control system with an almost periodic matrix of coefficients and the control in the form of feedback linear in phase variables is considered. It is assumed that the feedback coefficient is almost periodic and its frequency module, i. e. the smallest additive group of real numbers, including all the Fourier exponents of this coefficient, is contained in the frequency module of the coefficient matrix. The system under consideration is studied in the case of a zero average value of the matrix of coefficients. For the described class of systems, the control problem of the spectrum of irregular oscillations (asynchronous spectrum) with a target set of frequencies is solved. This task is as follows: to construct such a control from an admissible set so that the system closed by this control has almost periodic solutions, the set of Fourier exponents (frequency spectrum) that are contained in a predetermined subset; the intersection of the solution frequency modules and the coefficient matrix is trivial. The necessary and sufficient conditions for solvability of the control problem of the asynchronous spectrum are obtained.
研究了一类具有近似周期系数矩阵和反馈线性相位变量形式的线性控制系统。假设反馈系数几乎是周期性的,其频率模,即包含该系数的所有傅里叶指数的最小实数加性群,包含在系数矩阵的频率模中。本文研究了在系数矩阵平均值为零的情况下所考虑的系统。对于所描述的系统,解决了具有目标频率集的不规则振荡频谱(异步频谱)的控制问题。这个任务是这样的:从一个可容许的集合构造这样一个控制,使得这个控制所封闭的系统具有几乎周期解,即包含在预定子集中的傅立叶指数(频谱)的集合;解频率模块与系数矩阵的交点是平凡的。得到了异步频谱控制问题可解的充分必要条件。
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引用次数: 0
Correctness problem of the threshold method of modular sharing of secrets with masking transformation 带掩蔽变换的模块化秘密共享阈值方法的正确性问题
Pub Date : 2020-01-04 DOI: 10.29235/1561-8323-2019-63-6-662-671
A. F. Chernyavsky, A. Kolyada, A. Martinov, S. Y. Protasenya
The article formulates the principles of constructing threshold cryptographic schemes for secret sharing based on a modular coding and a linear masking function with an additive variational component of pseudo-random type. The main attention is paid to the correctness problem of schemes of the considered class within the limits of the accepted model. The congruent condition in the module of the secret-original ring of the masking function values in full and partial modular number systems is obtained. On the basis of the above-said, the method of correct implementation of the threshold principle of secret information sharing is developed. The proposed approach to solving the problem under study is demonstrated by specific numerical examples.
本文提出了基于模编码和伪随机型加性变分分量线性掩蔽函数的秘密共享门限密码方案的构造原理。主要关注被考虑类的方案在可接受模型范围内的正确性问题。得到了全模和部分模系统中掩模函数值在密原环模上的同余条件。在此基础上,提出了正确实施保密信息共享阈值原则的方法。通过具体的数值算例说明了所提出的求解问题的方法。
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引用次数: 0
Фермион с тремя массовыми параметрами: взаимодействие с внешними полями 有三个质量参数的费米翁:与外部磁场的相互作用
Pub Date : 2019-01-13 DOI: 10.29235/1561-8323-2018-62-6-661-667
V. V. Kisel, V. A. Pletyukhov, E. M. Ovsiyuk, Ya. A. Voynova, O. V. Veko, V. M. Red'kov
In the article, using the Gelfand–Yaglom general approach, a new 20-component wave equation for spin 1/2 fermion that is characterized by three mass parameters is derived. Based on the 20-component wave function three auxiliary bispinors are determined, in the absence of an external field, these bispinors obey three separate Dirac-like equations with different masses M 1 , M 2 , M 3 . In the presence of external electromagnetic fields, the main equation is not split into the separated equations; instead quite definite mixing of three Dirac-like equations arises. The model is extended to the curved space-time background. If the scalar space curvature differs from zero, then additional terms of geometrical interaction occur between three bispinor components. The model for fermion with three mass parameters allows for the restriction to the case of the neutral Majorana particle.
本文利用Gelfand-Yaglom一般方法,导出了一个新的自旋1/2费米子的20分量波动方程,该方程具有三个质量参数。在20分量波函数的基础上确定了三个辅助双量,在没有外场的情况下,这些双量服从三个独立的、具有不同质量m1、m2、m3的类狄拉克方程。在外加电磁场作用下,主方程不分解为分离方程;取而代之的是三个狄拉克式方程的明确混合。将该模型推广到弯曲时空背景。如果标量空间曲率不等于零,则在三个双量分量之间出现几何相互作用的附加项。具有三个质量参数的费米子模型允许对中性马约拉纳粒子的情况进行限制。
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引用次数: 1
Состав отходящих газов при каталитическом синтезе углеродных наноматериалов при пиролитическом разложении пропан-бутановой смеси 碳纳米材料催化合成中的退火气体组成
Pub Date : 2019-01-13 DOI: 10.29235/1561-8323-2018-62-6-685-693
Т. Н. Генарова, В. В. Грушевский, П. Н. Кривошеев, Олег Глебович Пенязьков, И. Ф. Буяков, Юлия Михайловна Дмитренко, С. А. Жданок, А. П. Чернухо
It is known that during the process of carbon nanomaterials synthesis, gaseous products and various unknown hydrocarbons are formed. Thus, the production of carbon nanomaterials could damage the environment. A detailed analysis of all gaseous products during the pyrolysis process is needed in order to clarify the nature of the formed substances and to control the technological characteristics of the catalyst. The chemical composition study of exhaust gases was made on the facility of propane-butane mixture pyrolysis for the carbon nanomaterial synthesis. The analysis of 16 polycyclic aromatic hydrocarbons (PAHs) of the extracts is made using a gas chromatography-mass spectrometry method. A quantitative analysis of gases was made by gas chromatography coupled with a heat conduction detector and a flame ionization detector. It was established that the concentrations of some PAHs exceed 14, 20, 90 and 100 times much as a maximum permissible concentration in the air. It was found that the appropriate devices of carbon nanomaterial production should be used in order to eliminate the PAHs that are formed.
众所周知,在碳纳米材料的合成过程中,会形成气态产物和各种未知的碳氢化合物。因此,碳纳米材料的生产可能会破坏环境。为了阐明形成物质的性质和控制催化剂的工艺特性,需要对热解过程中的所有气态产物进行详细的分析。在丙烷-丁烷混合热解装置上进行了碳纳米材料合成废气的化学成分研究。采用气相色谱-质谱联用方法对提取物中16种多环芳烃(PAHs)进行分析。采用气相色谱联用热传导检测器和火焰电离检测器对气体进行了定量分析。经确定,一些多环芳烃的浓度超过空气中最大允许浓度的14倍、20倍、90倍和100倍。研究发现,为了消除所形成的多环芳烃,应采用适当的碳纳米材料生产装置。
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引用次数: 2
Структуры и математические модели автокомпенсаторов мешающих излучений градиентного типа
Pub Date : 2019-01-13 DOI: 10.29235/1561-8323-2018-62-6-763-768
С. М. Костромицкий, А. П. Шумский, И. Н. Давыденко
In the article, using subsequent transformations of the structure and mathematical model of a classic gradient jammer canceller, the mathematical model and the structure of a gradient jammer canceller with a pre-processor are obtained. A new structure provides that the adaptation speed of a canceller does not depend on the spread of the eigenvalues of the input signal correlation matrix. An intermediate model provides the analysis of weight misadjustment of the classic gradient jammer canceller. The aim of the new mathematical model is a subsequent analysis of weight misadjustment of the jammer canceller with a stable adaptation speed.
本文通过对经典梯度干扰消除器的结构和数学模型的后续变换,得到了带预处理的梯度干扰消除器的数学模型和结构。一种新的结构使得消去器的自适应速度不依赖于输入信号相关矩阵特征值的扩散。一个中间模型分析了经典梯度干扰消除器的权值失调。该数学模型的目的是在稳定的自适应速度下对干扰器的权值失调进行后续分析。
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引用次数: 0
Реконструкция повреждений ротаторно-бицепитального комплекса при оперативном лечении переломов проксимального отдела плеча 扭转二头肌损伤的重建,手术治疗肩部近端骨折。
Pub Date : 2019-01-13 DOI: 10.29235/1561-8323-2018-62-6-732-738
O. A. Danilenko, E. R. Makarevich, N. S. Serdyuchenko, A. V. Malashko
The aim of the work was to improve the results of surgical treatment of patients having fractures of the proximal shoulder with the use of the approaches, including the reposition of bone fragments with adequate osteosynthesis and prevention of impingement syndrome, the reconstruction of all damaged structures of the rotator-bicipitale complex. A score assessment of the treatment results of 512 patients aged from 18 to 87 years old was performed, operated from 2004 to 2018 for the treatment of which the tactical approaches and the methods of surgical treatment developed by the authors aimed at restoring the rotator and bicipital elements were used. The use of the developed tactical approaches and methods made it possible to achieve a favorable outcome of treatment in 503 (98.2 %) patients. Thus, the reconstruction of injuries of the rotatory-bicipital complex is a promising way to improve the results of treatment in patients with fractures of the proximal shoulder.
这项工作的目的是通过使用该入路改善近端肩骨折患者的手术治疗效果,包括用充分的骨融合术重新定位骨碎片,预防撞击综合征,重建所有受损的肱二头肌复合体结构。对2004年至2018年手术的512例18 ~ 87岁患者的治疗结果进行评分,采用作者开发的旨在恢复旋转肌和肱二头肌的战术入路和手术治疗方法进行治疗。在503例(98.2%)患者中,采用已开发的战术途径和方法获得了良好的治疗结果。因此,肩关节旋转-肱二头复合体损伤的重建是改善近端肩关节骨折患者治疗效果的一种很有希望的方法。
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引用次数: 0
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Doklady Akademii nauk
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