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[Morphological changes of peripheral nerves following intraneural injection of local anesthetic]. [神经内注射局麻药后周围神经形态学改变]。
Pub Date : 1991-12-01
B Hoffmeister

Neurosensory disturbances of the third branch of the trigeminal nerve occur in rare cases without any operative treatment near the nerve involved. The most frequently affected nerve branches are the inferior alveolar nerve and the lingual nerve. We examined the problem of intraneural injection of local-anaesthetic solutions in an experimental study on animals. After intraneural injection of Articain (4%)-solution in the ischiadic nerve of Wistar rats and the lingual nerve of cats no toxic lesions were observed. It can be assumed that neurosensory disturbances caused by intraneural local-anaesthetic injection are the result of intraneural haematomas with consecutive fibrosis.

三叉神经第三支的神经感觉障碍发生在罕见的病例中,没有任何手术治疗的神经附近受累。最常受影响的神经分支是下牙槽神经和舌神经。我们在动物实验研究中探讨了局部麻醉溶液的神经内注射问题。Wistar大鼠坐骨神经和猫舌神经经神经内注射Articain(4%)溶液后,未见毒性损伤。可以认为,神经内局部麻醉注射引起的神经感觉障碍是神经内血肿伴连续纤维化的结果。
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引用次数: 0
[Influence of emotional stress and vasoconstrictor agents on heart rate and blood pressure]. 情绪应激和血管收缩剂对心率和血压的影响。
Pub Date : 1991-12-01
F U Meyer

With the administration of local anaesthetics is to expect in dependence of the vasoconstrictor a different cardiovascular reaction. An addition of epinephrine 0.001% directs a rise of the heart rate and a drop of the diastolic blood pressure; after norepinephrine 0.005% the heart rate shows a decrease and at the same time there is an increase of the systolic and diastolic blood pressure. The alterations caused by exogenous catecholamines are superposed by alterations caused by emotional stress (injection, tooth extraction). The endogenous alterations always take place in the same way.

随着局部麻醉剂的施用,期望在血管收缩剂的依赖性中出现不同的心血管反应。添加0.001%的肾上腺素可使心率升高,舒张压降低;去甲肾上腺素0.005%后心率下降,同时收缩压和舒张压升高。外源性儿茶酚胺引起的改变与情绪压力(注射、拔牙)引起的改变叠加。内源性的变化总是以同样的方式发生。
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引用次数: 0
[Peripheral oxygen saturation during dental surgery with and without premedication]. [术前和非术前牙科手术期间的外周氧饱和度]。
Pub Date : 1991-12-01
F Fiedler, G Lauer, J E Otten, J Hassel

83 adults undergoing dental surgical procedures in local anesthesia were monitored continuously with a pulse oximeter for hypoxemia. 30 patients received as premedication either a combination of a neuroleptic drug and an opiate or a benzodiazepine. There was a drop in the oxygen saturation in 80% of the patients with premedication but only in 66% of the patients without. There were statistical highly significant more periods of hypoxemia in patients with premedication compared to the others. (1548 periods versus 659 periods p less than 0.001). The kind of premedication/sedation does not influence the number of hypoxic episodes. We conclude that especially patients with premedication should only be treated by surgeons with sufficient clinical experience in coping with emergency situations.

83例在局部麻醉下接受牙科手术的成年人用脉搏血氧仪连续监测低氧血症。30名患者接受了抗精神病药物和阿片类药物或苯二氮卓类药物的联合用药。在接受药物治疗的患者中,80%的患者血氧饱和度下降,而在未接受药物治疗的患者中,这一比例仅为66%。与其他患者相比,用药前患者低氧血症的时间有统计学上的高度显著性。(1548期对659期,p < 0.001)。用药前/镇静的种类不影响缺氧发作的次数。我们的结论是,特别是有药物前治疗的患者,应该只由有足够临床经验的外科医生处理紧急情况。
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引用次数: 0
[Necroses and hematomas--two local complications in intraoral conduction anesthesia. Case report]. 坏死和血肿——口内传导麻醉的两种局部并发症。病例报告)。
Pub Date : 1991-12-01
U Krüger, G Nehse

According to the literature vascular lesions are reported in 6% of intraoral conduction anesthesia. A possible consequence is the intraarterial injection of catecholamin added local anesthetic. Due to a long lasting angiospasm necrosis of local mucosae and extraoral skin are possible. In a young female patient extraoral necrosis of parts of the skin of the lower lip and intraoral mucosa appeared, following intraoral conduction anesthesia. Subsequently a scar persisted needing a plastic cicatricotomy. Moreover sensitivity in the area of distribution of the mental nerve was deranged.

据文献报道,6%的口内传导麻醉有血管病变。一个可能的后果是动脉内注射儿茶酚胺加局部麻醉剂。由于长时间的血管痉挛,局部粘膜和口外皮肤可能出现坏死。一例年轻女性患者,经口内传导麻醉后,下唇部分皮肤及口内黏膜出现口外坏死。随后,疤痕持续存在,需要进行整形瘢痕切开术。此外,精神神经分布区域的敏感性也出现了紊乱。
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引用次数: 0
[Relative rigidity of standardized gutta-percha points]. [标准化杜仲胶点的相对刚性]。
Pub Date : 1991-12-01
R Weiger, M Dick, C Löst

Gutta-percha points often crack off when inserted in small and curved root canals before they have reached the full length of the canal. The goal of this investigation was to determine the relative rigidity of standardized gutta-percha points from different producers. It seems that not only significant differences between gutta-percha points of various producers, but also distinct variations between gutta-percha points from the same producer were detected. Several reasons for the differing rigidity of gutta-percha points are discussed.

杜胶胶在插入小而弯曲的根管时,在达到根管的全长之前经常会破裂。本调查的目的是确定来自不同生产商的标准化杜仲胶点的相对刚性。似乎不仅不同生产商的杜仲胶点数之间存在显著差异,而且同一生产商的杜仲胶点数之间也存在明显差异。讨论了杜仲胶点刚度不同的几个原因。
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引用次数: 0
[Introduction of anesthetics into the oral mucosa by iontophoresis]. 【通过离子导入将麻醉药引入口腔黏膜】。
Pub Date : 1991-12-01
W Böse

The results of this study of the behavior of anesthetics following ionic application showed great differences in terms of depth and duration of action. This is obviously attributable to different molecular structures resulting in variable rates of transport within the tissues.

本研究结果表明,离子应用后麻醉药的行为在作用深度和持续时间方面存在很大差异。这显然是由于不同的分子结构导致组织内运输速率的变化。
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引用次数: 0
[Clinical pharmacokinetics of lidocaine after intraoral nerve block]. 利多卡因经口神经阻滞后的临床药代动力学研究。
Pub Date : 1991-12-01
J E Eickbohm, H Wulf, C Hoffmann, C Becker

Aim of this study was to show the time course of plasma concentrations of 2% lignocaine with adrenalin at a concentration of 1:100,000. Four retinated third molars were removed in one session in 23 patients. For local anaesthesia in each patient we used 10 ml of Xylocaine 2% (Astra), which is commonly used in dentistry. The plasma-concentration was measured for the first 30 minutes after injection of the local anaesthetic using high pressure liquid chromatography (HPLC). Our results suggest that partially intravascular injection could not be avoided although careful aspiration was carried out before injecting. Neither subjective nor objective adverse central nervous effects were seen in our patients. Nevertheless we consider a peripheral intravenous cannula and ECG-monitoring strongly recommended in all major operations under local anaesthesia.

本研究的目的是显示2%的利多卡因血浆浓度与1:10万浓度的肾上腺素的时间过程。23例患者一次拔除4颗含视网膜的第三磨牙。对于每位患者的局部麻醉,我们使用10毫升2%的Xylocaine (Astra),这是牙科常用的麻醉。采用高压液相色谱法测定局部麻醉剂注射后30分钟的血药浓度。我们的结果表明,尽管在注射前进行了仔细的抽吸,但仍不能避免部分血管内注射。本组患者均未见主观或客观中枢神经不良反应。尽管如此,我们还是强烈建议在所有大的局部麻醉手术中使用外周静脉插管和心电图监测。
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引用次数: 0
[Outpatient dental surgery under anesthesiological monitoring. Investigation with 1022 patients at risk]. 在麻醉监护下的门诊牙科手术。1022例高危患者的调查]。
Pub Date : 1991-12-01
C G Schippers, A Bischoff, S Schlüpers Oehmen

The aim of the study was to explore retrospectively the risks of ambulatory treatment under local anaesthesia during dental operations of elderly patients. Anaesthetic care was divided into control and therapeutical measures. Among the previous disorders the hypertension and its sequelae proved to be the main risk factors. The need of anaesthetic intervention doubled, when the time of operation exceeded 30 min. Due to good interdisciplinary cooperation, 99.3% of the operations took their proper course.

本研究的目的是回顾性探讨老年患者牙科手术中局部麻醉下门诊治疗的风险。麻醉护理分为控制措施和治疗措施。在上述疾病中,高血压及其后遗症是主要的危险因素。当手术时间超过30 min时,麻醉干预的需求增加了一倍。由于良好的跨学科合作,99.3%的手术顺利进行。
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引用次数: 0
[Various factors influencing the local anesthetic effect of articaine]. [影响阿替卡因局麻效果的各种因素]。
Pub Date : 1991-12-01
E Reinhart, J Reuther, G Schargus, M Lipp, U Then

In a field study, the reduction in the anaesthetic effectiveness of Articain was investigated in relation to various influencing parameters. Both in the ZMK-Klinik (Dental Hospital) of Würzburg as well an in various independent practices, the local anaesthetic Articain was given to over 2000 patients in the course of dental treatment. With 12.1% of all test-subjects, inspite of the initial positive effectiveness upon application of the nerve-blocking anaesthetic, touch sensitivity and/or painfulness was established in the area concerned. Statistical evaluations of the recorded data of the test-subjects investigated showed a significantly higher quota of anaesthetic failure in the case of heavy cigarette consumption, chronic exposure to inhaled toxins as well as in the case of the intake of medicines of certain pharmaceutical types. Apart from that, a connection was also established between reduction in the effectiveness of the local anaesthetic and various treatments as well as the way in which the local anaesthetic was applied and the site of injection. Possible causes will be presented and discussed in relation to information from the literature on the subject.

在一项实地研究中,研究了各种影响参数与青蒿素麻醉效果降低的关系。在w茨堡的ZMK-Klinik(牙科医院)以及各种独立诊所,在牙科治疗过程中对2000多名患者进行了局部麻醉。在所有测试对象中,尽管在应用神经阻断麻醉剂后最初有积极的效果,但在有关区域建立了触摸敏感和/或疼痛。对所调查的测试对象的记录数据的统计评估表明,在大量吸烟、长期暴露于吸入毒素以及摄入某些药物类型的情况下,麻醉失败的比例明显更高。除此之外,还建立了局部麻醉效果的降低与各种治疗方法以及局部麻醉的使用方式和注射部位之间的联系。可能的原因将提出并讨论有关的信息,从文献的主题。
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引用次数: 0
[Problem of anesthetic failure]. 【麻醉失效的问题】。
Pub Date : 1991-12-01
B Fleiner, H Terheyden

Failure of local anesthetics is a common problem in dentistry. A sample of 210 dental practitioners was chosen at random and asked to evaluate the significance of anesthesia failure, comparing different injecting techniques. A standardized questionnaire, including a visual analogue scale for quantitative data, was distributed among the participants. The frequency of failure was indicated by most of the participants at 2% to 5% total. Considerably higher assessments were apparent in endodontics and abscess incisions. Rates of failure were said to be low in infraorbital nerve block, average in infiltration anesthesia and high in mandibular nerve block. These preliminary results indicate that a reliable anesthetic in dental treatment cannot always be provided.

局部麻醉药失效是牙科常见的问题。随机抽取210名牙科医生,对麻醉失败的意义进行评价,比较不同的注射技术。在参与者中分发了一份标准化问卷,其中包括定量数据的视觉模拟量表。大多数参与者表示失败的频率在2%到5%之间。牙髓学和脓肿切口的评估明显更高。眶下神经阻滞的失败率较低,浸润麻醉的失败率一般,下颌神经阻滞的失败率较高。这些初步结果表明,在牙科治疗中不可能总是提供可靠的麻醉剂。
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Deutsche zahnarztliche Zeitschrift
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