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Diabetes research and clinical practice最新文献

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When the summer camp ends: Short-term, post-camp deterioration of glycemic control in youth with type 1 diabetes 夏令营结束时：1型糖尿病青少年短期后血糖控制恶化。
IF 7.4 3区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Diabetes research and clinical practice
Pub Date : 2025-12-03 DOI: 10.1016/j.diabres.2025.113039
Georgia Sotiriou, Meropi Dimitriadou, Aggeliki Nemtsa, Evgenia Kavoura, Konstantina Pappa, Athanasios Christoforidis

Aims

To investigate short-term post-camp glycemic deterioration in youth with T1D using sensor-augmented or automated insulin delivery systems and to identify contributing factors.

Methods

This retrospective analysis included 93 children and adolescents with T1D using MiniMed™ CSII systems, attending a seven-day summer diabetes camp in Greece (2019–2025). Glycemic metrics, insulin dosing, carbohydrate intake, infusion set changes were assessed for the pre-camp week, the camp week, and the post-camp week.

Results

Glycemic control during camp was satisfactory and superior to pre-camp values. Post-camp, time in range (70–180 mg/dL) declined (64.53 %) compared with camp (71.27 %) and pre-camp (69.95 %), while time above range (>180 mg/dL and >250 mg/dL) increased. This short-term deterioration was consistent across all six years. Glucose variability peaked during camp (CV 35.21 %). MiniMed™780G users maintained better post-camp control than MiniMed™640G users (TIR 70.02 % vs. 55.43 %, p < 0.001). Post-camp, participants consumed more meals and carbohydrates and required higher total daily insulin (41.13 units/day, 0.84 U/kg). The TDD/Carbs ratio remained stable, and infusion set changes were less frequent during camp.

Conclusions

Children and adolescents with T1D maintain adequate glycemic control during camp, but experience a transient post-camp deterioration, underscoring the need for monitoring and individualized support during the week following camp.
目的：利用传感器增强或自动胰岛素输送系统研究青年T1D患者营后短期血糖恶化，并确定影响因素。方法：本回顾性分析包括93名使用MiniMed™CSII系统的T1D儿童和青少年，他们参加了希腊为期7天的糖尿病夏令营（2019-2025）。血糖指标、胰岛素剂量、碳水化合物摄入量、输液器变化在训练营前一周、训练营周和训练营后一周进行评估。结果：训练营期间血糖控制良好，优于训练营前。与营地（71.27 %）和营地前（69.95 %）相比，营地后在70 ~ 180 mg/dL范围内停留的时间（64.53 %）减少，而在180 ~ 180 mg/dL和250 mg/dL范围内停留的时间（> ~ 250 mg/dL）增加。这种短期恶化在所有六年中都是一致的。葡萄糖变异在营地期间达到峰值（CV 35.21 %）。与MiniMed™640G使用者相比，MiniMed™780G使用者在营地后保持了更好的控制（TIR为70.02 % vs. 55.43 %,p ）。结论：T1D儿童和青少年在营地期间维持了适当的血糖控制，但经历了短暂的营地后恶化，强调了在营地后一周进行监测和个性化支持的必要性。
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引用次数: 0
Integrated metabolomics and metagenomics analysis defines a unique signature of metabolic syndrome in a Thai population 综合代谢组学和宏基因组学分析定义了泰国人群中代谢综合征的独特特征
IF 7.4 3区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Diabetes research and clinical practice
Pub Date : 2025-12-01 DOI: 10.1016/j.diabres.2025.112491
G. Sweeney , S. Wannaiampikul , B. Lee , K. Prentice , J. Chen , R. Ayansola , A. Xu , K. Pantopoulos
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引用次数: 0
Global and mitochondrial epigenetic profiles in type 2 diabetes: Findings from the RICH study 2型糖尿病的整体和线粒体表观遗传谱：来自RICH研究的发现
IF 7.4 3区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Diabetes research and clinical practice
Pub Date : 2025-12-01 DOI: 10.1016/j.diabres.2025.112508
H.C. Low , H.L. Cheah , J.H. Lim , C.K.Y. Ong , Y.Q. Chin , C.K.M. Lim , Q. Ayub , W. Ratnam , T. Karupaiah , F. Daud , Z.A.M. Daud , Y.F. Pung
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引用次数: 0
Longitudinal changes in plasma proteomics after bariatric surgery: insights from 6 and 12-month follow-up 减肥手术后血浆蛋白质组学的纵向变化：来自6个月和12个月随访的见解
IF 7.4 3区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Diabetes research and clinical practice
Pub Date : 2025-12-01 DOI: 10.1016/j.diabres.2025.112532
D. Choi , S.H. Kwon
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引用次数: 0
Smart insole technology: the future for active measurement and offloading of the diabetic foot? 智能鞋垫技术：糖尿病足主动测量和卸载的未来？
IF 7.4 3区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Diabetes research and clinical practice
Pub Date : 2025-12-01 DOI: 10.1016/j.diabres.2025.112576
A. Gatt, C. Saliba Thorne, M. Bugeja, C. DeRaffaele, A. Saliba, C. Formosa
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引用次数: 0
Unique gut microbial signature among non-autoimmune (idiopathic) type 1 diabetes: Implications on glycemic control 非自身免疫性（特发性）1型糖尿病的独特肠道微生物特征：对血糖控制的影响
IF 7.4 3区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Diabetes research and clinical practice
Pub Date : 2025-12-01 DOI: 10.1016/j.diabres.2025.112496
S. Ashok , S.N. Seenivasan , A.K. Raghupathy , D. Vasudevan , B. Gajendran , K. Durairaj , S. Ramalingam , G. Manivel , D.S. Sathish , M. Sunderasan , K. Swaminathan , V. Ganasan
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引用次数: 0
Effect of dapagliflozin on liver parameters in treatment-naïve MAFLD patients: prospective observational study 达格列净对treatment-naïve MAFLD患者肝脏参数的影响：前瞻性观察研究
IF 7.4 3区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Diabetes research and clinical practice
Pub Date : 2025-12-01 DOI: 10.1016/j.diabres.2025.112516
A. Gautam , P.K. Agrawal , N. Pursnani , A.K. Gupta , S. Bansal , A. Kulshrestha
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引用次数: 0
Examination of stress assessment by measuring fingernail cortisol and social connections in elderly diabetics exercise 通过测量老年糖尿病患者运动中指甲皮质醇和社会联系的压力评估
IF 7.4 3区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Diabetes research and clinical practice
Pub Date : 2025-12-01 DOI: 10.1016/j.diabres.2025.112492
S. Okada , M. Furukawa , R. Takahashi , N. Tsutaya , E.A.C. Dilrukshi , M. Fujiwara , A. Oba , Y. Sato , S. Nomura
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引用次数: 0
Endothelial caveolin-1 deficiency drives aldosterone-mediated cardiovascular but not metabolic dysfunction 内皮小窝蛋白-1缺乏导致醛固酮介导的心血管功能障碍，而不是代谢功能障碍
IF 7.4 3区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Diabetes research and clinical practice
Pub Date : 2025-12-01 DOI: 10.1016/j.diabres.2025.112493
S.K. Gholami , S. Ranjit , F. Fazzila Abidin , E. Trefts , S.K. Mohd Hafiz Ngoo , A. Garza , L. Pojoga
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引用次数: 0
Analysis of risk factors for the development of ketosis-prone diabetes mellitus and predictive value of TyG index 酮症易感性糖尿病发生的危险因素分析及TyG指数的预测价值
IF 7.4 3区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Diabetes research and clinical practice
Pub Date : 2025-12-01 DOI: 10.1016/j.diabres.2025.112556
H. Tan, Z. Fan, Y. Liu, S. Zhang, S. Cholekho, H. Muhammad
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引用次数: 0
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