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Hydrocortisone-induced symptomatic sinus bradycardia. 氢化可的松诱发症状性窦性心动过缓。
Q4 Medicine
Drug and Therapeutics Bulletin
Pub Date : 2024-05-29 DOI: 10.1136/dtb.2024.252878rep
Mohammed Ahmed, Success Tobore Oyibo, Shailesh Dalvi, Richard Cowell
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引用次数: 0
Pharmaceutical company payments to NHS trusts 制药公司向国民保健服务托管机构付款
Q4 Medicine
Drug and Therapeutics Bulletin
Pub Date : 2024-05-06 DOI: 10.1136/dtb.2024.000031
BMJ Publishing Group Ltd
### Key points Analysis of data from the Disclosure UK database shows that more than 90% of NHS trusts in England received non-research-related payments from pharmaceutical companies between 2015 and 2018.1 The authors of the study used data from the Disclosure UK database (https://search.disclosureuk.org.uk/) which contains details of payments and benefits in kind made by the pharmaceutical industry to organisations and health professionals in the UK.1 Information relating to payments made during 4 years …
#### 要点 对英国信息披露数据库数据的分析表明，2015 年至 2018 年间，英格兰 90% 以上的 NHS 信托机构从制药公司获得了与研究无关的付款。1 研究报告的作者使用了英国信息披露数据库（https://search.disclosureuk.org.uk/）中的数据，该数据库包含制药行业向英国的组织和卫生专业人员支付的款项和实物福利的详细信息。1 与 4 年间的付款有关的信息 ...
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引用次数: 0
Reducing antibiotic use for acute sinusitis in children 减少儿童急性鼻窦炎的抗生素用量
Q4 Medicine
Drug and Therapeutics Bulletin
Pub Date : 2024-05-02 DOI: 10.1136/dtb.2024.000029
BMJ Publishing Group Ltd
### Key messages In children with acute sinusitis, antibiotic treatment had minimal benefit on symptom burden and duration, and the effect did not differ between those with and without coloured nasal discharge.1 This double-blind randomised placebo-controlled trial took place in primary care centres in the USA and involved 510 children aged 2–11 years with persistent or worsening symptoms of acute sinusitis and who scored ≥9 on the Pediatric Rhinosinusitis Symptom Scale …
### 1 这项双盲随机安慰剂对照试验在美国的初级保健中心进行，共有510名2-11岁的儿童参与，这些儿童患有持续或恶化的急性鼻窦炎症状，并且在小儿鼻窦炎症状量表中得分≥9分......
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引用次数: 0
Increasing awareness of the risk of death from a propanolol overdose 提高对过量服用普萘洛尔致死风险的认识
Q4 Medicine
Drug and Therapeutics Bulletin
Pub Date : 2024-05-02 DOI: 10.1136/dtb.2024.000030
BMJ Publishing Group Ltd
### Key messages A recently published coroner’s report has highlighted concerns that there may be a lack of awareness over the risks associated with an overdose of propranolol.1 A patient who had a history of mental illness was prescribed an antidepressant for anxiety and to help with sleep.1 He also had a history of suicidal ideation and had made previous suicide attempts. After he was discharged from the community mental health team, he consulted his general practitioner (GP) about symptoms of anxiety and physical symptoms including …
### 最近发表的一份验尸官报告强调了人们对过量服用普萘洛尔相关风险缺乏认识的担忧。1 一位有精神病史的患者因焦虑和帮助睡眠而被处方抗抑郁药。从社区精神卫生小组出院后，他向自己的全科医生咨询焦虑症状和躯体症状，包括...
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引用次数: 0
Prenatal use of antiepileptic drugs and childhood psychiatric disorders 产前使用抗癫痫药物与儿童精神障碍
Q4 Medicine
Drug and Therapeutics Bulletin
Pub Date : 2024-04-27 DOI: 10.1136/dtb.2024.000026
BMJ Publishing Group Ltd
### Key learning points A registry-based study has reinforced the need for safety warnings against using valproate during pregnancy because of an increased risk of early-onset developmental disorders in exposed children.1 This prospective cohort study used data on live-born singleton children of mothers with epilepsy from five Nordic countries to examine the association between prenatal use of antiepileptic medication and psychiatric and developmental disorders in exposed offspring.1 Children were followed up from birth until the …
### 这项前瞻性队列研究使用了来自五个北欧国家的、母亲患有癫痫的单胎活产婴儿的数据，研究了产前使用抗癫痫药物与受影响后代的精神和发育障碍之间的关系。
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引用次数: 0
Cytisine for smoking cessation. 用于戒烟的 Cytisine。
Q4 Medicine
Drug and Therapeutics Bulletin
Pub Date : 2024-04-25 DOI: 10.1136/dtb.2024.000009
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引用次数: 16
Recent updates from the BNF (BNF 87). BNF 的最新更新（BNF 87）。
Q4 Medicine
Drug and Therapeutics Bulletin
Pub Date : 2024-04-25 DOI: 10.1136/dtb.2024.000018

The BNF is jointly published by the Royal Pharmaceutical Society and BMJ. BNF is published in print twice a year and interim updates are issued and published monthly in the digital versions. The following summary provides a brief description of some recent key changes that have been made to BNF content.

BNF 由英国皇家药学会和 BMJ 联合出版。BNF 每年出版两次印刷版，每月发布一次临时更新，并在电子版中出版。以下摘要简要介绍了近期对 BNF 内容所做的一些重要更改。
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引用次数: 0
Delayed drug hypersensitivity reaction to secukinumab in a patient with hidradenitis suppurativa. 一名化脓性扁桃体炎患者对塞库单抗的迟发性药物超敏反应。
Q4 Medicine
Drug and Therapeutics Bulletin
Pub Date : 2024-04-25 DOI: 10.1136/dtb.2023.249684rep
Sasank Konda, Nayha Shetty, Ben Friedman, Jesse Veenstra
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引用次数: 0
Medicines and global warming: a complex problem 药品与全球变暖：一个复杂的问题
Q4 Medicine
Drug and Therapeutics Bulletin
Pub Date : 2024-04-09 DOI: 10.1136/dtb.2024.000003
James A Cave
The healthcare sector is responsible for 4.6% of global greenhouse gas emissions.1 Significant contributors to this carbon footprint are the biotech and pharmaceutical industries, directly from the running of these companies (sometimes called scope 1 emissions) and indirectly from purchased energy consumed (scope 2 emissions) and all other emissions indirectly associated with the companies—such as supply chains (scope 3 emissions).2 It is estimated that scope 1, 2 and 3 emissions of biotech and pharmaceutical companies accounted for 260 million tons of carbon dioxide equivalent emissions in 2021, higher than global emissions from the forestry and paper industry.2 There are particular …
医疗保健行业占全球温室气体排放量的 4.6%。2 据估计，2021 年生物技术和制药公司的范围 1、2 和 3 排放量占二氧化碳当量排放量的 2.6 亿吨，高于全球林业和造纸业的排放量。
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引用次数: 0
MHRA issues further update on fluoroquinolone safety MHRA 发布氟喹诺酮类药物安全性的进一步更新信息
Q4 Medicine
Drug and Therapeutics Bulletin
Pub Date : 2024-04-09 DOI: 10.1136/dtb.2024.000021
BMJ Publishing Group Ltd
### Key learning points The licensed indications for all systemic fluoroquinolones have been updated to restrict their use to situations in which other commonly recommended antibiotics are inappropriate.1 In August and September 2023, the Medicines and Healthcare products Regulatory Agency (MHRA) issued two safety updates on the use of fluoroquinolone antibiotics.1–3 The first update reminded healthcare professionals that systemic fluoroquinolone antibiotics are associated with a risk of …
### 1 2023 年 8 月和 9 月，药品和保健品监管局（MHRA）发布了两份关于氟喹诺酮类抗生素使用的安全性更新。1-3 第一份更新提醒医疗保健专业人员，全身用氟喹诺酮类抗生素与 ...
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引用次数: 0
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