Pub Date : 2024-04-01DOI: 10.1016/j.dmpk.2023.100825
Carley J.S. Heck, Raman Sharma, Gregory S. Walker, Matthew A. Cerny
{"title":"Hepatocyte formation, reactivity, and stability differences of acyl glucuronide and acyl coenzyme a conjugates","authors":"Carley J.S. Heck, Raman Sharma, Gregory S. Walker, Matthew A. Cerny","doi":"10.1016/j.dmpk.2023.100825","DOIUrl":"https://doi.org/10.1016/j.dmpk.2023.100825","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":"55 ","pages":"Article 100825"},"PeriodicalIF":2.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140917774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1016/j.dmpk.2023.100574
Joseph Grillo
{"title":"Practical use of mechanistic modeling to discern real word complex drug interactions","authors":"Joseph Grillo","doi":"10.1016/j.dmpk.2023.100574","DOIUrl":"https://doi.org/10.1016/j.dmpk.2023.100574","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":"55 ","pages":"Article 100574"},"PeriodicalIF":2.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140917807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1016/j.dmpk.2023.100564
Zubida Al-Majdoub
{"title":"This is no longer just about liver: LC-MS proteomics for organ exposure brain/kidney/gut/skin/placenta","authors":"Zubida Al-Majdoub","doi":"10.1016/j.dmpk.2023.100564","DOIUrl":"https://doi.org/10.1016/j.dmpk.2023.100564","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":"55 ","pages":"Article 100564"},"PeriodicalIF":2.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140917881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1016/j.dmpk.2023.100565
Christine Wegler
{"title":"LC-MS for identifying changes (or lack of it) in ADME across different cohorts","authors":"Christine Wegler","doi":"10.1016/j.dmpk.2023.100565","DOIUrl":"https://doi.org/10.1016/j.dmpk.2023.100565","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":"55 ","pages":"Article 100565"},"PeriodicalIF":2.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140917882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1016/j.dmpk.2023.100561
F. Peter Guengerich
{"title":"Drug metabolism: A half-century plus of progress, continued needs, and new opportunities","authors":"F. Peter Guengerich","doi":"10.1016/j.dmpk.2023.100561","DOIUrl":"https://doi.org/10.1016/j.dmpk.2023.100561","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":"55 ","pages":"Article 100561"},"PeriodicalIF":2.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140917918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1016/j.dmpk.2023.100806
Marina Nogueira , Stephanie Sanchez , Benlian Gao , Warda Amin , Sarah Thomas , Gong Yang , Ginger Milne
{"title":"Identification and characterization of novel metabolites of F2-isoprostanes","authors":"Marina Nogueira , Stephanie Sanchez , Benlian Gao , Warda Amin , Sarah Thomas , Gong Yang , Ginger Milne","doi":"10.1016/j.dmpk.2023.100806","DOIUrl":"https://doi.org/10.1016/j.dmpk.2023.100806","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":"55 ","pages":"Article 100806"},"PeriodicalIF":2.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140917999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1016/j.dmpk.2023.100809
Ankit Balhara
{"title":"Prediction and validation of fetal exposure to dual BCRP/P-GP drug substrates using the proteomics informed efflux ratio-relative expression factor (ER-REF) approach and PBPK modeling and simulation","authors":"Ankit Balhara","doi":"10.1016/j.dmpk.2023.100809","DOIUrl":"https://doi.org/10.1016/j.dmpk.2023.100809","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":"55 ","pages":"Article 100809"},"PeriodicalIF":2.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140918129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1016/j.dmpk.2023.100586
Brandon Bordeau
{"title":"Increasing the therapeutic index of ADCs with payload binding selectivity enhancers","authors":"Brandon Bordeau","doi":"10.1016/j.dmpk.2023.100586","DOIUrl":"https://doi.org/10.1016/j.dmpk.2023.100586","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":"55 ","pages":"Article 100586"},"PeriodicalIF":2.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140918304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：