{"title":"Substrate-dependent characteristics in the transport function of SLC19A3: examination of the aspect of its sensitivity to flavonoids","authors":"Hiroaki Yuasa, Saena Yamashita, Takahiro Yamashiro, Tomoya Yasujima","doi":"10.1016/j.dmpk.2023.100993","DOIUrl":"https://doi.org/10.1016/j.dmpk.2023.100993","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":"30 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141058823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-13DOI: 10.1016/j.dmpk.2023.100959
Kyungsun Moon, Sung-Hoon Ahn
{"title":"Pharmacokinetics of perfluoroocanoic acid and perfluorohexane sulfonic acid in various rat models","authors":"Kyungsun Moon, Sung-Hoon Ahn","doi":"10.1016/j.dmpk.2023.100959","DOIUrl":"https://doi.org/10.1016/j.dmpk.2023.100959","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":"129 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141058987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-13DOI: 10.1016/j.dmpk.2023.100898
Tingting Yan, Nana Yan, Yangliu Xia, Haiping Hao, Frank J. Gonzalez
{"title":"Hepatocyte CEBPA restricts the progression of liver fibrosis","authors":"Tingting Yan, Nana Yan, Yangliu Xia, Haiping Hao, Frank J. Gonzalez","doi":"10.1016/j.dmpk.2023.100898","DOIUrl":"https://doi.org/10.1016/j.dmpk.2023.100898","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":"189 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141518089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-13DOI: 10.1016/j.dmpk.2023.100980
Baron Bechtold, Katherine Lynch, Victoria Oyanna, Michael Ridge Call, John Clarke
{"title":"Rifampin- and silymarin-mediated pharmcokinetic interactions of pitavastatin, pravastatin, coproporphyrin I, and coproporphyrin III in a transgenic OATP1B mouse model","authors":"Baron Bechtold, Katherine Lynch, Victoria Oyanna, Michael Ridge Call, John Clarke","doi":"10.1016/j.dmpk.2023.100980","DOIUrl":"https://doi.org/10.1016/j.dmpk.2023.100980","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":"48 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141058813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Encequidar is a gut-restricted P-GP specific inhibitor that boosts oral bioavailability and inhibits intestinal secretion in rats and dogs.","authors":"Murali Subramanian, Aaliyah Shodeinde, Gregg Schwarzwalder, Ana Gonzalez, Josh Yu, Guangyu Zhao, Jia Hao, Xiaomin Liang, Yurong Lai, Raju Subramanian","doi":"10.1016/j.dmpk.2023.100989","DOIUrl":"https://doi.org/10.1016/j.dmpk.2023.100989","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":"31 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141058821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-13DOI: 10.1016/j.dmpk.2023.100940
Shantanu Roychowdhury, Kevin Thomas, Allison Liverar, Michell Martineau, Libby Bell, Lucus Albrecht
{"title":"De-risking idiosyncratic adverse drug reactions and toxicities in drug discovery utilizing a qualitative in-vitro high-throughput reactive metabolite trapping method","authors":"Shantanu Roychowdhury, Kevin Thomas, Allison Liverar, Michell Martineau, Libby Bell, Lucus Albrecht","doi":"10.1016/j.dmpk.2023.100940","DOIUrl":"https://doi.org/10.1016/j.dmpk.2023.100940","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":"4 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141058840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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