Pub Date : 2020-01-10DOI: 10.15406/ijcam.2020.13.00485
H. Khanal, R. Joshi, A. Upadhyay
The pressure exerted on the wall of arteries by the strength of the contraction of the heart is called Blood Pressure.1 Hypertension is a lifestyle disease that is characterized by abnormally high arterial blood pressure that is usually indicated by an adult systolic blood pressure of 140mm Hg or greater or a diastolic blood pressure of 90 mm Hg or greater.2 It is chiefly of unknown aetiology but may be due to a pre-existing condition such as a renal or endocrine disorder, that typically results in a thickening of arterial walls and hypertrophy of the left heart ventricle.3 Uncontrolled hypertension is a risk factor for various pathological conditions such as heart attack, heart failure, stroke, kidney disease and retinal haemorrhage.4 The disease has been appropriately nicknamed ‘silent-killer’ because in most patients hypertension does not have any symptom and usually goes unnoticed.5 Hypertension is a global health problem. Worldwide, approximately 26.4% of the adult population in 2000 had hypertension (26.6% of men and 26.1% of women), and 29.2% were projected to have this condition by 2025 (29.0% of men and 29.5% of women). The estimated total number of adults with hypertension in 2000 was 972million; 333million in economically developed countries and 639million in economically developing countries. The number of adults with hypertension in 2025 was predicted to increase by about 60% to a total of 1.56billion.6
{"title":"Anti- hypertensive activity of Ayurvedic medicinal plants","authors":"H. Khanal, R. Joshi, A. Upadhyay","doi":"10.15406/ijcam.2020.13.00485","DOIUrl":"https://doi.org/10.15406/ijcam.2020.13.00485","url":null,"abstract":"The pressure exerted on the wall of arteries by the strength of the contraction of the heart is called Blood Pressure.1 Hypertension is a lifestyle disease that is characterized by abnormally high arterial blood pressure that is usually indicated by an adult systolic blood pressure of 140mm Hg or greater or a diastolic blood pressure of 90 mm Hg or greater.2 It is chiefly of unknown aetiology but may be due to a pre-existing condition such as a renal or endocrine disorder, that typically results in a thickening of arterial walls and hypertrophy of the left heart ventricle.3 Uncontrolled hypertension is a risk factor for various pathological conditions such as heart attack, heart failure, stroke, kidney disease and retinal haemorrhage.4 The disease has been appropriately nicknamed ‘silent-killer’ because in most patients hypertension does not have any symptom and usually goes unnoticed.5 Hypertension is a global health problem. Worldwide, approximately 26.4% of the adult population in 2000 had hypertension (26.6% of men and 26.1% of women), and 29.2% were projected to have this condition by 2025 (29.0% of men and 29.5% of women). The estimated total number of adults with hypertension in 2000 was 972million; 333million in economically developed countries and 639million in economically developing countries. The number of adults with hypertension in 2025 was predicted to increase by about 60% to a total of 1.56billion.6","PeriodicalId":113120,"journal":{"name":"International Journal of Complementary and Alternative Medicine","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126877030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-09DOI: 10.15406/ijcam.2020.13.00484
D. Dwivedi, Nivedita Vats
Biofilm is a community of cells attached to either a biotic or abiotic surface enclosed in a complex exopolymeric substance (EPS).1 Biofilms allow micro–organisms to trap nutrients and withstand hostile environmental conditions by Quorum sensing (QS). It is widespread and well–known cell–to–cell communication phenomenon for the regulation of behaviors of biofilm formation and virulence.2–4 QS Comprises of chemical communication among bacteria involving formation, secretion, detection and reaction to molecules known as autoinducers (AI). Several serious infections are reported to be a result of biofilm formation and further it leads to chronic diseases. These Persistent infections is a challenge for public health on a global scale as it reduces the effectiveness of treatments and increases morbidity, mortality, and health care costs.5 Streptococcus mutans is an impotent pathogen and is a common cause of oral infections such as dental caries; S. mutans effectively utilizes dietary sucrose to synthesize large amounts of exo polysaccharides, which plays an important role in accumulation, adhesion, plaque matrix formation of microorganism, These processes in most cases lead to serious infections. The ability of micro-organism to from biofilm on host tissue surface is an important step in the development of infection.6 Due to poor hygienic condition and infection of pathogenic micro–organism creates difficulties and presently wide range of antibiotics are being used for treating infections but due to their adverse effect and antibiotic resistance is now paying attention towards natural biologically active herbal compounds as an alternative medicine.7,8 Natural compounds Curcumin commonly found in Curcuma longa it’s a diarylheptanoid, the principal component of Curcuma longa. Negundoside it’s a type of glycoside found in Vitex negundo are available plant species in India. It is a reputed medicinal herb and employed as a traditional cure in Asian system of medicine (Indian, Chinese and Malaysian) for variety of disease conditions.9–12 The objective of present study was to identify natural compounds like Curcumin and Negundoside for their potential against biofilm producing activity.
{"title":"Comparative study of herbal compounds curcumin and negundoside on the biofilm producing property of streptococcus mutans isolated from oral infection","authors":"D. Dwivedi, Nivedita Vats","doi":"10.15406/ijcam.2020.13.00484","DOIUrl":"https://doi.org/10.15406/ijcam.2020.13.00484","url":null,"abstract":"Biofilm is a community of cells attached to either a biotic or abiotic surface enclosed in a complex exopolymeric substance (EPS).1 Biofilms allow micro–organisms to trap nutrients and withstand hostile environmental conditions by Quorum sensing (QS). It is widespread and well–known cell–to–cell communication phenomenon for the regulation of behaviors of biofilm formation and virulence.2–4 QS Comprises of chemical communication among bacteria involving formation, secretion, detection and reaction to molecules known as autoinducers (AI). Several serious infections are reported to be a result of biofilm formation and further it leads to chronic diseases. These Persistent infections is a challenge for public health on a global scale as it reduces the effectiveness of treatments and increases morbidity, mortality, and health care costs.5 Streptococcus mutans is an impotent pathogen and is a common cause of oral infections such as dental caries; S. mutans effectively utilizes dietary sucrose to synthesize large amounts of exo polysaccharides, which plays an important role in accumulation, adhesion, plaque matrix formation of microorganism, These processes in most cases lead to serious infections. The ability of micro-organism to from biofilm on host tissue surface is an important step in the development of infection.6 Due to poor hygienic condition and infection of pathogenic micro–organism creates difficulties and presently wide range of antibiotics are being used for treating infections but due to their adverse effect and antibiotic resistance is now paying attention towards natural biologically active herbal compounds as an alternative medicine.7,8 Natural compounds Curcumin commonly found in Curcuma longa it’s a diarylheptanoid, the principal component of Curcuma longa. Negundoside it’s a type of glycoside found in Vitex negundo are available plant species in India. It is a reputed medicinal herb and employed as a traditional cure in Asian system of medicine (Indian, Chinese and Malaysian) for variety of disease conditions.9–12 The objective of present study was to identify natural compounds like Curcumin and Negundoside for their potential against biofilm producing activity.","PeriodicalId":113120,"journal":{"name":"International Journal of Complementary and Alternative Medicine","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121320599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-11DOI: 10.15406/ijcam.2020.13.00483
Shubhashree Mn, Doddamani Sh, Bhavya Bm, K BharaliB
{"title":"Ayurvedic management of uterine fibroids: a case report","authors":"Shubhashree Mn, Doddamani Sh, Bhavya Bm, K BharaliB","doi":"10.15406/ijcam.2020.13.00483","DOIUrl":"https://doi.org/10.15406/ijcam.2020.13.00483","url":null,"abstract":"","PeriodicalId":113120,"journal":{"name":"International Journal of Complementary and Alternative Medicine","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121884713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-21DOI: 10.15406/ijcam.2019.12.00481
Marilene Cabral do Nascimento, C. Tesser, Sousa Mc
Abbreviations: SUS, brazilian unified health system; TCIM, traditional, complementary, and integrative medicine; PHC, primary health care; PNPIC, brazilian national policy of integrative and complementary practices; PMAQ, brazilian national program for access and quality improvement of Primary Care; MS, brazilian ministry of health; CNPq, national council for scientific and technological development of brazil; BIREME, latin american and caribbean center on health sciences information
{"title":"Traditional, complementary and integrative medicines in the Brazilian health primary care","authors":"Marilene Cabral do Nascimento, C. Tesser, Sousa Mc","doi":"10.15406/ijcam.2019.12.00481","DOIUrl":"https://doi.org/10.15406/ijcam.2019.12.00481","url":null,"abstract":"Abbreviations: SUS, brazilian unified health system; TCIM, traditional, complementary, and integrative medicine; PHC, primary health care; PNPIC, brazilian national policy of integrative and complementary practices; PMAQ, brazilian national program for access and quality improvement of Primary Care; MS, brazilian ministry of health; CNPq, national council for scientific and technological development of brazil; BIREME, latin american and caribbean center on health sciences information","PeriodicalId":113120,"journal":{"name":"International Journal of Complementary and Alternative Medicine","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124559087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-21DOI: 10.15406/ijcam.2019.12.00480
C. Peters, Mohana Kumari Vp, Peters Vm
The Ayurveda describes a set of complex clinical conditions with frequent, abnormal miction, collectively called Prameha, that in many ways correlate with obesity, metabolic syndrome, and diabetes mellitus. Obesity, metabolic syndrome, and diabetes mellitus have in common that they are all three metabolic disorders. In the pathogenesis of Prameha, the role of intermediate metabolites is vital because it is an acquired disease due to incorrect metabolism of nutrients. In Ayurveda, Ama refers to toxic intermediates of digestion and metabolism due to incompletely digested food.
{"title":"Diabetes mellitus type 2 from the perspective of ayurveda, a case study","authors":"C. Peters, Mohana Kumari Vp, Peters Vm","doi":"10.15406/ijcam.2019.12.00480","DOIUrl":"https://doi.org/10.15406/ijcam.2019.12.00480","url":null,"abstract":"The Ayurveda describes a set of complex clinical conditions with frequent, abnormal miction, collectively called Prameha, that in many ways correlate with obesity, metabolic syndrome, and diabetes mellitus. Obesity, metabolic syndrome, and diabetes mellitus have in common that they are all three metabolic disorders. In the pathogenesis of Prameha, the role of intermediate metabolites is vital because it is an acquired disease due to incorrect metabolism of nutrients. In Ayurveda, Ama refers to toxic intermediates of digestion and metabolism due to incompletely digested food.","PeriodicalId":113120,"journal":{"name":"International Journal of Complementary and Alternative Medicine","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123925754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-19DOI: 10.15406/ijcam.2019.12.00479
G. Jensen
Fibromyalgia syndrome (FMS) is a chronic musculoskeletal pain disorder with unknown cause.1 Chronic diffuse pain, stiffness, multiple tender points, fatigue, poor sleep, and increased pain response to pressure (allodynia) are classic symptoms of FMS.2 FMS affects approximately 2% of the population and is more common in women with a ratio of about 7:1 between women and men. Current research points to both central and peripheral nervous system dysfunctions including altered nociceptor sensitivity, as well as systemic inflammation,3 including increased levels of proinflammatory cytokines such as Tumor Necrosis Factor-α (TNF-α ).4 FMS has symptomatic overlap with another chronic pain disorder, Chronic fatigue syndrome (CFS). It has been postulated that both FMS and CFS could have underlying microbial etiologies.5,6 Furthermore, similarities in symptoms between FMS and CFS and “sickness behavior” implicate an immune component.7-9 Sickness behavior results from the release of proinflammatory cytokines by leukocytes in response to bacterial lipopolysaccharide and other toxins and leads to low-grade systemic inflammation which has been implicated in chronic pain, depression, and fatigue,10,11 the hallmark symptoms of FMS and CFS.
{"title":"Bacteria in blood from fibromyalgia patients include the Aquabacterium genus, producing metabolites with inflammatory properties in vitro. Results from a pilot study","authors":"G. Jensen","doi":"10.15406/ijcam.2019.12.00479","DOIUrl":"https://doi.org/10.15406/ijcam.2019.12.00479","url":null,"abstract":"Fibromyalgia syndrome (FMS) is a chronic musculoskeletal pain disorder with unknown cause.1 Chronic diffuse pain, stiffness, multiple tender points, fatigue, poor sleep, and increased pain response to pressure (allodynia) are classic symptoms of FMS.2 FMS affects approximately 2% of the population and is more common in women with a ratio of about 7:1 between women and men. Current research points to both central and peripheral nervous system dysfunctions including altered nociceptor sensitivity, as well as systemic inflammation,3 including increased levels of proinflammatory cytokines such as Tumor Necrosis Factor-α (TNF-α ).4 FMS has symptomatic overlap with another chronic pain disorder, Chronic fatigue syndrome (CFS). It has been postulated that both FMS and CFS could have underlying microbial etiologies.5,6 Furthermore, similarities in symptoms between FMS and CFS and “sickness behavior” implicate an immune component.7-9 Sickness behavior results from the release of proinflammatory cytokines by leukocytes in response to bacterial lipopolysaccharide and other toxins and leads to low-grade systemic inflammation which has been implicated in chronic pain, depression, and fatigue,10,11 the hallmark symptoms of FMS and CFS.","PeriodicalId":113120,"journal":{"name":"International Journal of Complementary and Alternative Medicine","volume":"242 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122700631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-18DOI: 10.15406/ijcam.2019.12.00478
T. H. Coulidiati, Emmanuel A. M. Thiombiano, M. J. Bangou, P. Sombié, M. Kiendrebeogo
Inflammation is a vital immunological process which is indispensable to animal’s survival.1 Persistent inflammation state can lead to chronic inflammation that can contribute to many common diseases2 from infectious to physiological dysfunctioning.3,4 Reactive oxygen species (ROS) and nitrogen oxygen species (NOS) are produced during inflammatory processes, and also contribute to amplifying oxidative stress phenomenon.5 Oxidative stress and inflammation are two linked pathophysiological processes.6 Regulation of reactive species has proven to attenuate the inflammation.7 Modern drugs used to treat different forms of inflammatory diseases are known to cause severe side effects,8 therefore it is urgent to find a new source of efficient drugs with minimum side effects.
{"title":"Comparative study of in vitro antioxidant and anti-inflammatory potentials of two malvaceae used in folk medicine in Burkina Faso","authors":"T. H. Coulidiati, Emmanuel A. M. Thiombiano, M. J. Bangou, P. Sombié, M. Kiendrebeogo","doi":"10.15406/ijcam.2019.12.00478","DOIUrl":"https://doi.org/10.15406/ijcam.2019.12.00478","url":null,"abstract":"Inflammation is a vital immunological process which is indispensable to animal’s survival.1 Persistent inflammation state can lead to chronic inflammation that can contribute to many common diseases2 from infectious to physiological dysfunctioning.3,4 Reactive oxygen species (ROS) and nitrogen oxygen species (NOS) are produced during inflammatory processes, and also contribute to amplifying oxidative stress phenomenon.5 Oxidative stress and inflammation are two linked pathophysiological processes.6 Regulation of reactive species has proven to attenuate the inflammation.7 Modern drugs used to treat different forms of inflammatory diseases are known to cause severe side effects,8 therefore it is urgent to find a new source of efficient drugs with minimum side effects.","PeriodicalId":113120,"journal":{"name":"International Journal of Complementary and Alternative Medicine","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129755469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-14DOI: 10.15406/ijcam.2019.12.00476
Akiyo Yoshioka, H. Bando, Y. Nishikiori, A. Nakanishi
In the Complementary and alternative medicine (CAM) and Integrated Medicine (IM), hydrotherapy and balneotherapy have been important treatment. They have several pleiotropic effects, such as thermal effects, buoyancy, hydrostatic pressure, viscous resistance and chemical effects. There is clinical efficacy to various diseases or states, including neck pain, low back pain, knee osteoarthritis, Parkinson disease, and so on. New trial with health promotion strategy with balneotherapy has been reported along World Federation of Hydrotherapy and Climatotherapy.
{"title":"Recent status of hydrotherapy and balneotherapy with clinical beneficial effects","authors":"Akiyo Yoshioka, H. Bando, Y. Nishikiori, A. Nakanishi","doi":"10.15406/ijcam.2019.12.00476","DOIUrl":"https://doi.org/10.15406/ijcam.2019.12.00476","url":null,"abstract":"In the Complementary and alternative medicine (CAM) and Integrated Medicine (IM), hydrotherapy and balneotherapy have been important treatment. They have several pleiotropic effects, such as thermal effects, buoyancy, hydrostatic pressure, viscous resistance and chemical effects. There is clinical efficacy to various diseases or states, including neck pain, low back pain, knee osteoarthritis, Parkinson disease, and so on. New trial with health promotion strategy with balneotherapy has been reported along World Federation of Hydrotherapy and Climatotherapy.","PeriodicalId":113120,"journal":{"name":"International Journal of Complementary and Alternative Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130646969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-04DOI: 10.15406/ijcam.2019.12.00474
G. Jensen, K. Benson
Over many decades, practitioners of alternative and complementary medicine have used the study of the living human blood to guide nonmainstream treatment strategies. Schools of thinking developed over time, teaching practitioners an alternative vocabulary to what was being observed by microscopy observations of their patients’ blood. This was at times where mainstream medicine considered the blood a sterile environment, and alternative claims of seeing bacterial and fungal forms were disregarded as ignorant and unscientific.
{"title":"The blood as a diagnostic tool in chronic illness with obscure microbial involvement: A critical review","authors":"G. Jensen, K. Benson","doi":"10.15406/ijcam.2019.12.00474","DOIUrl":"https://doi.org/10.15406/ijcam.2019.12.00474","url":null,"abstract":"Over many decades, practitioners of alternative and complementary medicine have used the study of the living human blood to guide nonmainstream treatment strategies. Schools of thinking developed over time, teaching practitioners an alternative vocabulary to what was being observed by microscopy observations of their patients’ blood. This was at times where mainstream medicine considered the blood a sterile environment, and alternative claims of seeing bacterial and fungal forms were disregarded as ignorant and unscientific.","PeriodicalId":113120,"journal":{"name":"International Journal of Complementary and Alternative Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123188103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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