Drug and alcohol dependence最新文献

{"title":"Is cannabis legalization associated with treatment completion? A study of pregnant women admitted for cannabis use in substance use treatment facilities, 2020–2022","authors":"Rogie Royce Carandang ,&nbsp;Taeho Greg Rhee ,&nbsp;Toan Ha ,&nbsp;Shayna D. Cunningham","doi":"10.1016/j.drugalcdep.2026.113023","DOIUrl":"10.1016/j.drugalcdep.2026.113023","url":null,"abstract":"<div><h3>Background</h3><div>Cannabis is the most used illicit substance during pregnancy in the United States. While cannabis legislation is associated with prevalence and access to care, its relationship with treatment completion among pregnant women is unclear. This study examined the association between cannabis legalization and treatment completion among pregnant women admitted for cannabis use from 2020 to 2022.</div></div><div><h3>Methods</h3><div>This retrospective cross-sectional analysis used data from the Treatment Episode Data Set-Discharge (TEDS-D) to analyze treatment completion among pregnant women aged 12 or older who were admitted for cannabis use (n = 13,088) across states with fully legalized, partially legalized (medical use only), or illegal cannabis policies. Multivariable-adjusted logistic regression was used to assess the association between legalization status and treatment completion, with subgroup analyses by treatment setting and referral source.</div></div><div><h3>Results</h3><div>Among pregnant women admitted for cannabis use, 28.3 % completed treatment. Compared to states where cannabis remained illegal, those in states with fully legalized cannabis had significantly lower odds of treatment completion (adjusted odds ratio [AOR], 0.33 [95 % confidence interval, 0.27–0.41]), with a similar trend in states with partial legalization (AOR, 0.33 [0.28–0.40]). The negative association between cannabis legislation and treatment completion was more pronounced in outpatient settings than in residential programs, and stronger among court/other referrals than among voluntary referrals.</div></div><div><h3>Conclusions</h3><div>Cannabis legalization may be negatively associated with treatment completion among pregnant women admitted for cannabis use. Further research is needed to identify policy-related barriers and develop evidence-based interventions that improve treatment engagement and retention in this vulnerable population.</div></div>","PeriodicalId":11322,"journal":{"name":"Drug and alcohol dependence","volume":"279 ","pages":"Article 113023"},"PeriodicalIF":3.6,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145923356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":11322,"journal":{"name":"Drug and alcohol dependence","volume":"282 ","pages":"Article 113086"},"PeriodicalIF":3.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146216305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Cross sectional multi-sample study of nonfatal overdose in adolescents and young adults in the fentanyl era” [Drug Alcohol Depend. 276 (2025) 112921]","authors":"Amy M. Yule ,&nbsp;Amy S.B. Bohnert ,&nbsp;Ty A. Ridenour ,&nbsp;Barrett Montgomery ,&nbsp;Timothy E. Wilens ,&nbsp;Maureen Walton ,&nbsp;Erin E. Bonar ,&nbsp;Lisa Saldana ,&nbsp;Lynn E. Fiellin ,&nbsp;Danica K. Knight ,&nbsp;Yang Yang ,&nbsp;Jason Williams ,&nbsp;Sazid Khan ,&nbsp;Liann Tucker ,&nbsp;Feker Wondimagegnehu ,&nbsp;Kym Ahrens","doi":"10.1016/j.drugalcdep.2025.112991","DOIUrl":"10.1016/j.drugalcdep.2025.112991","url":null,"abstract":"","PeriodicalId":11322,"journal":{"name":"Drug and alcohol dependence","volume":"278 ","pages":"Article 112991"},"PeriodicalIF":3.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145688768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prescribing of controlled substances to adolescents and young adults enrolled in Medicaid, 2001–2019","authors":"Greta Bushnell ,&nbsp;Mark Olfson ,&nbsp;Kristen Lloyd ,&nbsp;Stephanie Shiau ,&nbsp;Tobias Gerhard ,&nbsp;Katherine M Keyes ,&nbsp;Deborah Hasin ,&nbsp;Magdalena Cerdá ,&nbsp;Hillary Samples","doi":"10.1016/j.drugalcdep.2025.112975","DOIUrl":"10.1016/j.drugalcdep.2025.112975","url":null,"abstract":"<div><h3>Objective</h3><div>To examine nationwide trends in the prescribing of controlled medications to early adolescents, adolescents, and young adults enrolled in public insurance (Medicaid) from 2001 to 2019.</div></div><div><h3>Methods</h3><div>The study utilized US Medicaid data covering publicly insured enrollees from 43 states (2001–2019). Early adolescents (10–12<!--> <!-->y), adolescents (13–17<!--> <!-->y), and young adults (18–24<!--> <!-->y, 25–29<!--> <!-->y) with ≥ 10 months enrollment in each calendar year were included. Filled prescription for opioids, stimulants, benzodiazepines, Z-hypnotics, barbiturates, and gabapentin were identified. In each calendar year, annual proportions with 1 +  controlled medication, 2 +  classes of controlled medications, and each controlled medication were estimated.</div></div><div><h3>Results</h3><div>In 2019, the sample included 17.9 million enrollees (53 % female). The annual proportion prescribed any controlled medication peaked at 17.5 % in early adolescents (2003), 20.6 % in adolescents (2009), and 34.1 % (18–24<!--> <!-->y) and 47.0 % (25–29<!--> <!-->y) in young adults (2010). By 2019, the proportions declined to 11.7 % (early adolescents), 12.6 % (adolescents), 16.2 % (18–24<!--> <!-->y), and 23.9 % (25–29<!--> <!-->y). Trends varied by medication and age. The largest absolute decline was in the proportion with an opioid filled (2010 =29.8 %, 2019 =11.2 %, young adults 18–24<!--> <!-->y; 2003 =14.3 %, 2019 =4.4 %, adolescents). In contrast, the proportion with a stimulant fill increased, with eight-fold increases in young adults 25–29<!--> <!-->y (2001 =0.3 %, 2019 =2.6 %). Benzodiazepine and Z-hypnotic use peaked in 2010 and declined through 2019.</div></div><div><h3>Conclusions</h3><div>In the past two decades, there were increases in stimulant prescriptions among young Medicaid enrollees. The declines in opioid, benzodiazepines, barbiturate and Z-hypnotic prescribing are encouraging and may indicate more cautious prescribing related to greater awareness of harms such as misuse and overdose, along with policy initiatives.</div></div>","PeriodicalId":11322,"journal":{"name":"Drug and alcohol dependence","volume":"278 ","pages":"Article 112975"},"PeriodicalIF":3.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145770446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":11322,"journal":{"name":"Drug and alcohol dependence","volume":"282 ","pages":"Article 113085"},"PeriodicalIF":3.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146216304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reciprocal relationships among youth social media use, internalizing symptoms, and substance use","authors":"Xia Zheng ,&nbsp;Meng Yang ,&nbsp;Ruobing Li ,&nbsp;Wenbo Li ,&nbsp;Nicole Lis ,&nbsp;Hsien-Chang Lin","doi":"10.1016/j.drugalcdep.2025.113018","DOIUrl":"10.1016/j.drugalcdep.2025.113018","url":null,"abstract":"<div><h3>Objective</h3><div>Mental health, substance use, and social media are three important, inter-related factors influencing youth development. This study examines the dynamic, reciprocal relationships among social media use, internalizing mental health symptoms, and substance use (e-cigarette, alcohol, cigarette, and marijuana) among U.S. adolescents.</div></div><div><h3>Methods</h3><div>Data were from restricted Population Assessment of Tobacco and Health (PATH) Study, Waves 4, 4.5, and 5 (2016–2019). The sample included 7759U.S. adolescents (weighted N = 15,032,305) who completed all three waves. Weighted generalized structural equation models with lagged dependent variables were performed to examine the reciprocal relationships between youth’s social media use frequency, internalizing symptoms, and use of substances. Each variable has a dual role as both a predictor and outcome across waves, with earlier waves predicting subsequent ones, to assess bidirectional influences over time.</div></div><div><h3>Results</h3><div>Higher social media use and internalizing symptoms were associated with higher odds of subsequent e-cigarette, alcohol, and marijuana use. Higher social media use predicted higher odds of e-cigarette use (AOR=1.33, <em>p</em> &lt; 0.001) and alcohol use (AOR=1.19, <em>p</em> &lt; 0.001). Internalizing symptoms predicted higher odds of cigarette use (AOR=1.71, 95 % CI=1.15–2.53). Social media use also predicted greater odds of experiencing internalizing symptoms (AORs=1.05, all <em>p</em>s &lt; 0.01). We found both similarities and differences in the patterns of the reciprocal pathways overtime across the four substances.</div></div><div><h3>Conclusions</h3><div>Our study reveals a complex and dynamic relationship among social media use, mental health, and substance use among youth. The findings support the need for integrative interventions that simultaneously address mental health, social media behaviors, and substance use risk.</div></div>","PeriodicalId":11322,"journal":{"name":"Drug and alcohol dependence","volume":"278 ","pages":"Article 113018"},"PeriodicalIF":3.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145880252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful hepatitis C elimination through decentralized treatment in Dutch addiction care: A RE-AIM based evaluation","authors":"Daan W. Von den Hoff ,&nbsp;Floor A.C. Berden ,&nbsp;Annemarie Noordeloos ,&nbsp;Thomas Knuijver ,&nbsp;Arnt F.A. Schellekens ,&nbsp;Joost P.H. Drenth","doi":"10.1016/j.drugalcdep.2025.113014","DOIUrl":"10.1016/j.drugalcdep.2025.113014","url":null,"abstract":"<div><h3>Background</h3><div>People who use drugs (PWUD) are an important population of focus for hepatitis C virus (HCV) elimination. Case-finding and treatment of these patients in outpatient specialist care is a challenge due to population specific barriers. Screening and treatment integrated in addiction care might overcome these barriers. With this study we aim to evaluate the implementation of a decentralized PWUD-HCV care model.</div></div><div><h3>Methods</h3><div>We conducted a multicenter prospective observational study in Dutch addiction care centers to assess a decentralized HCV care pathway for PWUD. Implementation of HCV-care within addiction care was evaluated using the Reach-Effectiveness-Adoption-Implementation-Maintenance (RE-AIM) framework. Viral elimination, defined as the proportion of identified HCV-RNA positive PWUD achieving sustained virologic response (SVR), was the primary outcome.</div></div><div><h3>Results</h3><div>Reach: 870 anti-HCV tests were performed, 29 HCV-RNA positive PWUD were enrolled. Effectiveness: 23 patients initiated and completed on-site treatment, three patients were referred for treatment, two patients were lost to follow-up and one patient refused treatment. All patients tested for SVR achieved SVR, one patient was lost to follow-up before SVR test. The elimination rate was 86 % (25/29). Adoption: five out of eleven addiction care organizations (45 %) implemented decentralized HCV care within addiction care. Implementation fidelity was high.</div></div><div><h3>Conclusion</h3><div>This study demonstrates that successfully implemented decentralized HCV care within addiction services is feasible and highly effective, achieving an elimination rate of 86 %. However, adoption of decentralized HCV care was limited, underscoring the need for targeted strategies to enhance implementation. Our findings support expanding of decentralized HCV care models in addiction settings to meet HCV elimination targets.</div></div>","PeriodicalId":11322,"journal":{"name":"Drug and alcohol dependence","volume":"279 ","pages":"Article 113014"},"PeriodicalIF":3.6,"publicationDate":"2025-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145923351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inequities in blunt use across multiple socio-demographic intersections among US adults","authors":"Allison M. Glasser ,&nbsp;Jessica K. Jensen ,&nbsp;Kymberle L. Sterling ,&nbsp;Andrea C. Villanti","doi":"10.1016/j.drugalcdep.2025.113019","DOIUrl":"10.1016/j.drugalcdep.2025.113019","url":null,"abstract":"<div><h3>Introduction</h3><div>Blunts (cigars with tobacco replaced or mixed with cannabis) incur health risks from exposure to tobacco and cannabis and are disproportionately used by young adults, people identifying as Black/African American (B/AA), people with lower socioeconomic status (SES), and people with mental health issues. This study described patterns of blunt use among US adults with multiple identities or circumstances increasing risk for blunt use.</div></div><div><h3>Methods</h3><div>We used Wave 6 (2021) (US adults; N = 30,516) of the Population Assessment of Tobacco and Health Study to examine the association between current blunt use and race (B/AA vs. non-B/AA) +  mental health (symptoms of internalizing/externalizing conditions) and socioeconomic status (SES; receipt of government assistance) using weighted multivariable logistic regression models, stratified by age (young adults [YAs] 18–34 vs. adults 35 + years).</div></div><div><h3>Results</h3><div>In 2021, 8.4 % of YAs and 1.4 % of adults 35 +  currently used blunts. Compared to people with joint advantage (e.g., non-B/AA + high SES), those identifying as B/AA with low SES (aOR=5.10, 95 % CI=4.16–6.26), high internalizing (aOR=4.83, 95 % CI=3.70–6.32), or externalizing conditions (aOR=4.74, 95 % CI=3.47–6.48) had greater odds of using blunts. The magnitude of the association between identifying as B/AA and having low SES (alone and jointly) and blunt use was greater among adults 35 +  years (vs. YAs).</div></div><div><h3>Conclusions</h3><div>Blunt use was most prevalent among B/AA adults with low SES or those who experienced mental health conditions. The magnitude of some inequities was greater among adults 35 + . Social and structural interventions to reduce blunt use among US adults could improve health equity.</div></div>","PeriodicalId":11322,"journal":{"name":"Drug and alcohol dependence","volume":"279 ","pages":"Article 113019"},"PeriodicalIF":3.6,"publicationDate":"2025-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145883289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Population reach, feasibility and acceptability of digital therapeutics for smoking cessation among people living with HIV: Results of the Quitting Matters pilot trial","authors":"R. Vilardaga ,&nbsp;F.J. McClernon ,&nbsp;O. Akingbule ,&nbsp;P. Mannelli ,&nbsp;S.M. Thomas ,&nbsp;J.M. Davis ,&nbsp;M.F. Gray ,&nbsp;C. Arnold ,&nbsp;I. Chow Kai Reyes ,&nbsp;R. Ashare ,&nbsp;M. Paukner ,&nbsp;L.R. Pacek","doi":"10.1016/j.drugalcdep.2025.113015","DOIUrl":"10.1016/j.drugalcdep.2025.113015","url":null,"abstract":"<div><h3>Introduction</h3><div>Tobacco use is disproportionately prevalent among people living with HIV (PWH) and is a significant contributor to morbidity and mortality in this population. Reaching communities of PWH to facilitate smoking cessation is challenging. Digital Therapeutics (DTx) can facilitate widespread implementation and adoption of smoking cessation treatments for PWH.</div></div><div><h3>Methods</h3><div>We compared the feasibility and acceptability (primary outcomes) and preliminary efficacy (secondary outcome) of a DTx tailored to PWH -- Learn to Quit-HIV (LTQ-<em>H</em>) -- versus a gold standard smoking cessation DTx (QuitGuide) in a remote pilot randomized controlled trial. All participants received nicotine replacement therapy and were assessed at weeks 4, 8, and 12.</div></div><div><h3>Results</h3><div>During a 13-month period, we remotely recruited a sample of PWH (n = 41) across the United States, with randomization leading to a higher proportion of LTQ-<em>H</em> users with high levels of cannabis use. Digital markers of DTx use indicated that compared to QuitGuide, assignment to LTQ-<em>H</em> led to significantly greater number of device interactions (3610 vs 2086; RR=93.14; 95 % CI: 14.70–590; p &lt; 0.001), and a four-fold increase in mean interactions with active smoking cessation content (8.5 vs. 2.15; Cohen’s d=0.91; p &lt; 0.001). At week 12, in an adjusted model, LTQ-<em>H</em> resulted in numerically greater, but not statistically significant, biochemically verified 7-day point prevalence abstinence versus QuitGuide (18.2 % vs 15.8 %; aOR=6.97, 95 % CI: 0.65–74.33).</div></div><div><h3>Conclusions</h3><div>While participants assigned to LTQ-<em>H</em> had proportionally more features known to predict low quit rates (e.g. cannabis use), LTQ-<em>H</em> showed promising population reach, device engagement, and smoking outcomes. A hybrid effectiveness-implementation trial will evaluate this novel DTx in a larger sample of PWH.</div></div><div><h3>Implications</h3><div>The study highlights the potential of DTx to address the high prevalence of tobacco use among people with HIV. Compared to QuitGuide (gold standard DTx developed by NCI), LTQ-<em>H</em> showed promising participant engagement and smoking cessation outcomes. These findings suggest that LTQ-<em>H</em> could be a valuable tool for smoking cessation in people with HIV, warranting further investigation in larger trials to evaluate its effectiveness and implementation feasibility.</div></div>","PeriodicalId":11322,"journal":{"name":"Drug and alcohol dependence","volume":"279 ","pages":"Article 113015"},"PeriodicalIF":3.6,"publicationDate":"2025-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145923353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are there differences in gradual versus abrupt smoking cessation quit attempts and success by social grade? A population study in England","authors":"Sharon Cox ,&nbsp;Lion Shahab ,&nbsp;Claire Garnett ,&nbsp;Nicola Lindson ,&nbsp;Sarah Jackson","doi":"10.1016/j.drugalcdep.2025.113017","DOIUrl":"10.1016/j.drugalcdep.2025.113017","url":null,"abstract":"<div><h3>Background and aims</h3><div>Smoking rates remain higher among individuals from less advantaged social grades, who tend to be less successful when they try to quit. Abrupt quitting may be more successful than cutting down first, though evidence is mixed. It is not clear whether the quit methods chosen, and their effects, differ by social grade. This study aimed to: (1) compare the prevalence of gradual versus abrupt quit attempts across social grades; (2) examine the association between quit method and quit success; and (3) assess whether social grade moderates this association.</div></div><div><h3>Methods</h3><div>We used data from 27,390 adults in England who reported a past-year quit attempt in the Smoking Toolkit Study (2006–2025). Quit method used (gradual vs. abrupt) and quitting success were self-reported. Logistic regression analyses examined the two-way interaction between quit method and social grade (ABC1 =more advantaged vs. C2DE=less advantaged) and success, adjusting for sociodemographic and smoking-related covariates.</div></div><div><h3>Results</h3><div>People from less advantaged social grades were less likely to attempt to quit abruptly (53.2 % [95 % CI: 52.3–54.0 %] vs. 57.4 % [56.4–58.4 %]). Abrupt quitting was associated with higher odds of success compared with gradual quitting (OR = 1.70; 95 % CI: 1.58–1.84) providing no clear evidence this was moderated by social grade (interaction OR = 1.13; 95 % CI: 0.97–1.33, <em>p</em> = 0.14).</div></div><div><h3>Conclusion</h3><div>People who choose to quit abruptly are more likely to quit successfully than people who choose to quit gradually, irrespective of their social grade. However, people from less advantaged social grades are less likely to choose to quit abruptly.</div></div>","PeriodicalId":11322,"journal":{"name":"Drug and alcohol dependence","volume":"279 ","pages":"Article 113017"},"PeriodicalIF":3.6,"publicationDate":"2025-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145914266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}