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European Society for Medical Oncology (ESMO) 欧洲肿瘤医学学会（ESMO）
IF 10.6 2区 医学 Q1 ONCOLOGY
ESMO Open
Pub Date : 2026-07-01 Epub Date: 2026-07-03 DOI: 10.1016/S2059-7029(26)02208-8
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引用次数: 0
49P NSD2 inhibition as a therapeutic strategy for melanoma 抑制NSD2作为黑色素瘤的治疗策略
IF 10.6 2区 医学 Q1 ONCOLOGY
ESMO Open
Pub Date : 2026-07-01 Epub Date: 2026-07-03 DOI: 10.1016/j.esmoop.2026.107829
Q. Zhao , T. Liu , Y. Zou
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引用次数: 0
89P Immunotherapy outcomes in uncommon non-endometrioid, non-serous endometrial carcinomas: A multicenter real-world study 罕见的非子宫内膜样、非浆液性子宫内膜癌的免疫治疗结果：一项多中心真实世界研究
IF 10.6 2区 医学 Q1 ONCOLOGY
ESMO Open
Pub Date : 2026-07-01 Epub Date: 2026-07-02 DOI: 10.1016/j.esmoop.2026.108115
L.R. Nogueira, P. Fernandez Montes, T. Zumarraga Lizundia, I. Martínez Martín, R. Sanchez Bayona, J. Plata Fernández, A. Maderuelo González, N. Rubio Bertos, P. Tolosa Ortega, A. Beltran de Santa Olalla, M. Alva Bianchi, L. Lema Roso, E. Ciruelos, L.M. Manso Sanchez, A. Madariaga Urrutia
{"title":"89P Immunotherapy outcomes in uncommon non-endometrioid, non-serous endometrial carcinomas: A multicenter real-world study","authors":"L.R. Nogueira, P. Fernandez Montes, T. Zumarraga Lizundia, I. Martínez Martín, R. Sanchez Bayona, J. Plata Fernández, A. Maderuelo González, N. Rubio Bertos, P. Tolosa Ortega, A. Beltran de Santa Olalla, M. Alva Bianchi, L. Lema Roso, E. Ciruelos, L.M. Manso Sanchez, A. Madariaga Urrutia","doi":"10.1016/j.esmoop.2026.108115","DOIUrl":"10.1016/j.esmoop.2026.108115","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"11 ","pages":"Article 108115"},"PeriodicalIF":10.6,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148452390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
102eP Diagnostic concordance of mismatch repair immunohistochemistry with germline pathogenic variants in Lynch syndrome-associated endometrial cancer 102eP错配修复免疫组织化学与Lynch综合征相关子宫内膜癌种系致病变异的诊断一致性
IF 10.6 2区 医学 Q1 ONCOLOGY
ESMO Open
Pub Date : 2026-07-01 Epub Date: 2026-07-02 DOI: 10.1016/j.esmoop.2026.108128
T. Akmandor, M. Scott, D. Thind, A. Rosenthal, R. Arora
{"title":"102eP Diagnostic concordance of mismatch repair immunohistochemistry with germline pathogenic variants in Lynch syndrome-associated endometrial cancer","authors":"T. Akmandor, M. Scott, D. Thind, A. Rosenthal, R. Arora","doi":"10.1016/j.esmoop.2026.108128","DOIUrl":"10.1016/j.esmoop.2026.108128","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"11 ","pages":"Article 108128"},"PeriodicalIF":10.6,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148452400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
96eP Frailty and malnutrition as prognostic factors in advanced endometrial cancer: A real-world study from Tunisia 虚弱和营养不良是晚期子宫内膜癌的预后因素：一项来自突尼斯的现实世界研究
IF 10.6 2区 医学 Q1 ONCOLOGY
ESMO Open
Pub Date : 2026-07-01 Epub Date: 2026-07-02 DOI: 10.1016/j.esmoop.2026.108122
C. Belfekih Hassen, I. Lajnef, S. Mhamdi, L. Dhouibi, Y. Kotti, H. Zelaiti, A. Haddoui, M. Balti, J.B. Ayari, S. Fendri Ep Ben Chelbia, S. Ben Nasr
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引用次数: 0
33eP Prognostic value of hypoalbuminemia and change in body mass index during and after definitive chemoradiation in locally advanced carcinoma cervix patients: Experience in a tertiary care hospital 低白蛋白血症和体重指数变化对局部晚期宫颈癌患者放化疗期间和放疗后的预后价值：一家三级医院的经验
IF 10.6 2区 医学 Q1 ONCOLOGY
ESMO Open
Pub Date : 2026-07-01 Epub Date: 2026-07-02 DOI: 10.1016/j.esmoop.2026.108059
S. Kr
{"title":"33eP Prognostic value of hypoalbuminemia and change in body mass index during and after definitive chemoradiation in locally advanced carcinoma cervix patients: Experience in a tertiary care hospital","authors":"S. Kr","doi":"10.1016/j.esmoop.2026.108059","DOIUrl":"10.1016/j.esmoop.2026.108059","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"11 ","pages":"Article 108059"},"PeriodicalIF":10.6,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148452478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
9P Overcoming chemoresistance in HNF-1β-positive OCCC: Synergistic lethality of GSK-3 inhibition and cisplatin via a "Dual-Lock” mechanism of ROS storm and MDM2-p53-mediated apoptosis 克服hnf -1β阳性OCCC的化疗耐药：GSK-3抑制和顺铂通过ROS风暴和mdm2 -p53介导的细胞凋亡的“双锁”机制的协同致死性
IF 10.6 2区 医学 Q1 ONCOLOGY
ESMO Open
Pub Date : 2026-07-01 Epub Date: 2026-07-02 DOI: 10.1016/j.esmoop.2026.108034
M. Matsuoka, N. Kawahara, K. Umehara, Y. Sakamoto, J. Kamibayashi, M. Akinishi, S. Sugimoto, R. Maekawa, R. Kawaguchi, F. Kimura
{"title":"9P Overcoming chemoresistance in HNF-1β-positive OCCC: Synergistic lethality of GSK-3 inhibition and cisplatin via a \"Dual-Lock” mechanism of ROS storm and MDM2-p53-mediated apoptosis","authors":"M. Matsuoka, N. Kawahara, K. Umehara, Y. Sakamoto, J. Kamibayashi, M. Akinishi, S. Sugimoto, R. Maekawa, R. Kawaguchi, F. Kimura","doi":"10.1016/j.esmoop.2026.108034","DOIUrl":"10.1016/j.esmoop.2026.108034","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"11 ","pages":"Article 108034"},"PeriodicalIF":10.6,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148452544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
7P Inhibition of glycolysis and stimulation of mitochondrial biogenesis induce ROS-dependent selective cell death in HNF-1β–positive clear cell carcinoma 在hnf -1β阳性透明细胞癌中，糖酵解抑制和线粒体生物发生刺激可诱导ros依赖性选择性细胞死亡
IF 10.6 2区 医学 Q1 ONCOLOGY
ESMO Open
Pub Date : 2026-07-01 Epub Date: 2026-07-02 DOI: 10.1016/j.esmoop.2026.108032
N. Kawahara, S. Yamanaka, M. Matsuoka, J. Kamibayashi, S. Sugimoto, R. Kawaguchi, F. Kimura
{"title":"7P Inhibition of glycolysis and stimulation of mitochondrial biogenesis induce ROS-dependent selective cell death in HNF-1β–positive clear cell carcinoma","authors":"N. Kawahara, S. Yamanaka, M. Matsuoka, J. Kamibayashi, S. Sugimoto, R. Kawaguchi, F. Kimura","doi":"10.1016/j.esmoop.2026.108032","DOIUrl":"10.1016/j.esmoop.2026.108032","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"11 ","pages":"Article 108032"},"PeriodicalIF":10.6,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148452593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
153P Efficacy and safety of lenvatinib in patients with thymic epithelial tumors: A retrospective, multicenter study lenvatinib对胸腺上皮肿瘤患者的疗效和安全性：一项回顾性、多中心研究
IF 10.6 2区 医学 Q1 ONCOLOGY
ESMO Open
Pub Date : 2026-07-01 Epub Date: 2026-07-03 DOI: 10.1016/j.esmoop.2026.107957
J. Park, S. Lee, J.B. Lee, S.M. Lim, H.R. Kim, B.C. Cho, M.H. Hong
{"title":"153P Efficacy and safety of lenvatinib in patients with thymic epithelial tumors: A retrospective, multicenter study","authors":"J. Park, S. Lee, J.B. Lee, S.M. Lim, H.R. Kim, B.C. Cho, M.H. Hong","doi":"10.1016/j.esmoop.2026.107957","DOIUrl":"10.1016/j.esmoop.2026.107957","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"11 ","pages":"Article 107957"},"PeriodicalIF":10.6,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148582688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
151P Dual HER2 TKI blockade with pyrotinib and lapatinib in advanced HER2-positive breast cancer 151P联合罗替尼和拉帕替尼阻断晚期HER2阳性乳腺癌的HER2 TKI
IF 10.6 2区 医学 Q1 ONCOLOGY
ESMO Open
Pub Date : 2026-07-01 Epub Date: 2026-07-03 DOI: 10.1016/j.esmoop.2026.107955
J. Mehta
{"title":"151P Dual HER2 TKI blockade with pyrotinib and lapatinib in advanced HER2-positive breast cancer","authors":"J. Mehta","doi":"10.1016/j.esmoop.2026.107955","DOIUrl":"10.1016/j.esmoop.2026.107955","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"11 ","pages":"Article 107955"},"PeriodicalIF":10.6,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148582690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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