Pub Date : 2025-03-01DOI: 10.1016/j.esmoop.2025.104167
P. Launay
{"title":"11P Preclinical evaluation of an anti-transferrin receptor antibody drug conjugate targeting triple-negative breast cancer","authors":"P. Launay","doi":"10.1016/j.esmoop.2025.104167","DOIUrl":"10.1016/j.esmoop.2025.104167","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"10 ","pages":"Article 104167"},"PeriodicalIF":7.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143547804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-01DOI: 10.1016/j.esmoop.2025.104257
A. Avan , H. Azari , H. Ibrahim Alshekarchi , G.J. Peters , G.A. Ferns , E. Giovannetti
{"title":"96P Exploiting metabolic reprogramming via targeting novel genetic variant in urocanate hydratase 1 in histidine catabolism as a potential therapeutic approach in the treatment of colorectal cancer","authors":"A. Avan , H. Azari , H. Ibrahim Alshekarchi , G.J. Peters , G.A. Ferns , E. Giovannetti","doi":"10.1016/j.esmoop.2025.104257","DOIUrl":"10.1016/j.esmoop.2025.104257","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"10 ","pages":"Article 104257"},"PeriodicalIF":7.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143547807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-01DOI: 10.1016/j.esmoop.2025.104256
A. Botticelli , S. Lonardi , G. Lombardi , G. Curigliano , S. Scagnoli , S. Pisegna , E. Crimini , S. Verkhovskaia , C. Cremolini , E. Capoluongo , M. Biffoni , U. De Giorgi , P.F. Conte , M. Aglietta , L. Fornaro , E. Fenocchio , C. Tondini , G. Giannini , G. Blandino , P. Marchetti
{"title":"95O Atezolizumab plus ipatasertib shows promise in extending survival for patients with PI3K/AKT/PTEN-altered advanced solid tumors: An exploratory analysis of the ROME trial","authors":"A. Botticelli , S. Lonardi , G. Lombardi , G. Curigliano , S. Scagnoli , S. Pisegna , E. Crimini , S. Verkhovskaia , C. Cremolini , E. Capoluongo , M. Biffoni , U. De Giorgi , P.F. Conte , M. Aglietta , L. Fornaro , E. Fenocchio , C. Tondini , G. Giannini , G. Blandino , P. Marchetti","doi":"10.1016/j.esmoop.2025.104256","DOIUrl":"10.1016/j.esmoop.2025.104256","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"10 ","pages":"Article 104256"},"PeriodicalIF":7.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143547808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-01DOI: 10.1016/j.esmoop.2025.104208
O. Mirallas , K. Raskina , A. Di Muzio , A. Mel Olano , A.M. Calahorro García , G. Pretelli , A. Hernando Calvo , P. Mascaró Baselga , K.S. Vega Cano , V. Galvao Aguiar , M. Sanz , M.J. Lostes Bardaji , A. Oberoi , V. Sanchez Perez , G. Alonso Casal , I. Braña , R.D.A. Toledo , M. Vieito , R. Dienstmann , E. Garralda
{"title":"49P Outcome of patients with early-onset cancer in phase I trials with immune checkpoint inhibitors","authors":"O. Mirallas , K. Raskina , A. Di Muzio , A. Mel Olano , A.M. Calahorro García , G. Pretelli , A. Hernando Calvo , P. Mascaró Baselga , K.S. Vega Cano , V. Galvao Aguiar , M. Sanz , M.J. Lostes Bardaji , A. Oberoi , V. Sanchez Perez , G. Alonso Casal , I. Braña , R.D.A. Toledo , M. Vieito , R. Dienstmann , E. Garralda","doi":"10.1016/j.esmoop.2025.104208","DOIUrl":"10.1016/j.esmoop.2025.104208","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"10 ","pages":"Article 104208"},"PeriodicalIF":7.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143548244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-01DOI: 10.1016/j.esmoop.2025.104217
Z.M. Zaïr , G. Butterworth , M. Shalaby , E. Ostarijas , F. Thistlethwaite
{"title":"58P Toxicity profile of T cell engagers in early phase clinical trials: A systematic review and meta-analysis","authors":"Z.M. Zaïr , G. Butterworth , M. Shalaby , E. Ostarijas , F. Thistlethwaite","doi":"10.1016/j.esmoop.2025.104217","DOIUrl":"10.1016/j.esmoop.2025.104217","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"10 ","pages":"Article 104217"},"PeriodicalIF":7.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143548507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-01DOI: 10.1016/j.esmoop.2025.104210
J. Zhou
{"title":"51P A preliminary study on the application of a strong combination induction of immune checkpoint inhibitors with targeted therapy and chemotherapy in head and neck tumors","authors":"J. Zhou","doi":"10.1016/j.esmoop.2025.104210","DOIUrl":"10.1016/j.esmoop.2025.104210","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"10 ","pages":"Article 104210"},"PeriodicalIF":7.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143552494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-01DOI: 10.1016/j.esmoop.2025.104156
L. Ma , P. Fan , P. Tao , J. Wang , W. Lu , Y. Zhang , H. Tong
{"title":"1P Multimodal integration of radiology, pathology and transcriptomics for prediction of response to neoadjuvant therapy in patients with retroperitoneal liposarcoma","authors":"L. Ma , P. Fan , P. Tao , J. Wang , W. Lu , Y. Zhang , H. Tong","doi":"10.1016/j.esmoop.2025.104156","DOIUrl":"10.1016/j.esmoop.2025.104156","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"10 ","pages":"Article 104156"},"PeriodicalIF":7.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143552604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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