Yesim Tuyji-Tok, A. Şener, Aysegul Aksoy-Gokmen, T. Demirdal, Selçuk Kaya
Background: Although there have been significant improvements in treatment strategies, hepatitis C infection is still among the most critical public health problems worldwide. Upon entry of hepatitis C virus (HCV) into host liver cells, many antagonist immune responses are induced, including the production of regulatory T cells (Tregs). The main function of Tregs is coordinating an appropriate immune response, including suppression of this response once it is no longer needed. Tregs protect cells from immunopathologic damage of HCVspecific T cells but, on the other hand, cause viral persistence, cirrhosis and hepatocellular carcinoma (HCC). In this study, we aimed to determine whether the evaluation of Tregs in hepatitis C patients was a useful method for indicating disease chronicity. Materials and Methods: The peripheral blood samples were taken from sixty volunteers, including 30 non-cirrhotic chronic hepatitis C patients and 30 healthy controls selected from infectious diseases outpatient/clinic service applicants. Their CD4+CD25high FoxP3+CD152+CD127low Treg distributions were measured by flow cytometry, using recently identified markers combined. Results: Treg percentages of the subjects with hepatitis C infection (7.97±1.25) were significantly higher than those of the healthy control group (4.29±1.37) (p<0.05). Additionally, the percentages of Tregs were strongly correlated with HCV RNA load (r=0.725, p<0.05) as well as serum AFP levels (r=0.711, p<0.05). Conclusion: Tregs are thought to play an important role in the immunology of HCV infection, thereby providing a promising method for the prediction of disease prognosis and for potentially developing new therapeutic strategies by targeting the Treg.
{"title":"Evaluation of Regulatory T Cells in Chronic Hepatitis C Patients","authors":"Yesim Tuyji-Tok, A. Şener, Aysegul Aksoy-Gokmen, T. Demirdal, Selçuk Kaya","doi":"10.36519/idcm.2021.68","DOIUrl":"https://doi.org/10.36519/idcm.2021.68","url":null,"abstract":"Background: Although there have been significant improvements in treatment strategies, hepatitis C infection is still among the most critical public health problems worldwide. Upon entry of hepatitis C virus (HCV) into host liver cells, many antagonist immune responses are induced, including the production of regulatory T cells (Tregs). The main function of Tregs is coordinating an appropriate immune response, including suppression of this response once it is no longer needed. Tregs protect cells from immunopathologic damage of HCVspecific T cells but, on the other hand, cause viral persistence, cirrhosis and hepatocellular carcinoma (HCC). In this study, we aimed to determine whether the evaluation of Tregs in hepatitis C patients was a useful method for indicating disease chronicity. Materials and Methods: The peripheral blood samples were taken from sixty volunteers, including 30 non-cirrhotic chronic hepatitis C patients and 30 healthy controls selected from infectious diseases outpatient/clinic service applicants. Their CD4+CD25high FoxP3+CD152+CD127low Treg distributions were measured by flow cytometry, using recently identified markers combined. Results: Treg percentages of the subjects with hepatitis C infection (7.97±1.25) were significantly higher than those of the healthy control group (4.29±1.37) (p<0.05). Additionally, the percentages of Tregs were strongly correlated with HCV RNA load (r=0.725, p<0.05) as well as serum AFP levels (r=0.711, p<0.05). Conclusion: Tregs are thought to play an important role in the immunology of HCV infection, thereby providing a promising method for the prediction of disease prognosis and for potentially developing new therapeutic strategies by targeting the Treg.","PeriodicalId":11964,"journal":{"name":"European Journal of Clinical Microbiology and Infectious Diseases","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79162810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-30DOI: 10.36519/10.36519/idcm.2021.71
E. M. Saricaoğlu, Ayda Gholizadeh, Cemre Kırım, Elif Yunt, Ihsan Mert Turk, İlker Anıl Celik, Kardelennur Yıldırım, Pelin Ozbakir, A. Azap
Objective: The Internet is increasingly preferred as a source of health-related information. However, several studies revealed deficiencies in the quality of web-based health information. Therefore, this study aimed to analyze the content and design of influenza vaccine-related websites. Materials and Methods: This study was conducted using a search engine, Google Search, in the Turkish language. We identified 15 influenza-related search terms, and for each term, the top ten links on the first page were included in the study after removing duplicate links. Then, we evaluated identified websites in terms of content and design criteria. Results: Seventy-one links related to influenza vaccination were evaluated in our study. The mean content criteria score of all selected websites was 11.5 points. While academic websites received the highest contents point with 22.5, news and hospital sites remained under the average with 10.5 and 8.9 points, respectively. Thirty-eight per cent of the websites had aesthetic/content professionalism, and 77.5% included contact information. References were shown only in 14.1% of websites. The websites with higher design criteria did not have higher content points. Conclusion: The Internet remains a frequently referenced source of information. The accuracy of the information on health topics included on the Internet is important in terms of public health. Unfortunately, according to our study, the top websites giving information on influenza vaccination were not well designed and had insufficient content.
{"title":"Do the Most Cited Web Sources Provide Proper Information on Influenza Vaccination?","authors":"E. M. Saricaoğlu, Ayda Gholizadeh, Cemre Kırım, Elif Yunt, Ihsan Mert Turk, İlker Anıl Celik, Kardelennur Yıldırım, Pelin Ozbakir, A. Azap","doi":"10.36519/10.36519/idcm.2021.71","DOIUrl":"https://doi.org/10.36519/10.36519/idcm.2021.71","url":null,"abstract":"Objective: The Internet is increasingly preferred as a source of health-related information. However, several studies revealed deficiencies in the quality of web-based health information. Therefore, this study aimed to analyze the content and design of influenza vaccine-related websites. Materials and Methods: This study was conducted using a search engine, Google Search, in the Turkish language. We identified 15 influenza-related search terms, and for each term, the top ten links on the first page were included in the study after removing duplicate links. Then, we evaluated identified websites in terms of content and design criteria. Results: Seventy-one links related to influenza vaccination were evaluated in our study. The mean content criteria score of all selected websites was 11.5 points. While academic websites received the highest contents point with 22.5, news and hospital sites remained under the average with 10.5 and 8.9 points, respectively. Thirty-eight per cent of the websites had aesthetic/content professionalism, and 77.5% included contact information. References were shown only in 14.1% of websites. The websites with higher design criteria did not have higher content points. Conclusion: The Internet remains a frequently referenced source of information. The accuracy of the information on health topics included on the Internet is important in terms of public health. Unfortunately, according to our study, the top websites giving information on influenza vaccination were not well designed and had insufficient content.","PeriodicalId":11964,"journal":{"name":"European Journal of Clinical Microbiology and Infectious Diseases","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83967971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Refik Saydam: A Pioneer in the Fight Against Infectious Diseases","authors":"Cemaliye Başaran","doi":"10.36519/idcm.2021.109","DOIUrl":"https://doi.org/10.36519/idcm.2021.109","url":null,"abstract":"","PeriodicalId":11964,"journal":{"name":"European Journal of Clinical Microbiology and Infectious Diseases","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88223388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Wulandari, Rebriarina Hapsari, Mujahidah, Desvita Sari, Iva Puspitasari, D. Pramukarso
Introduction: Invasive candidiasis has emerged as a significant public health problem in recent years, and candidemia is the most common form. Identification of the Candida species is important since some Candida species showed an increasing trend of resistance to commonly used antifungal agents. This study was conducted to describe primary demographic data and the distribution of Candida species along with their antifungal susceptibility profiles among patients with candidemia. Methods: We conducted a retrospective descriptive study on patients with candidemia and their Candida species identification and antifungal susceptibility testing (ID&AST) results at Dr. Kariadi Hospital, Indonesia, from January 2017 to December 2020. Identification and antifungal susceptibility testing of Candida species during these 4 years were determined using the Vitek-2 system. After collecting the data, it was analyzed by using SPSS 25.sav. The data was analyzed distributively, and was presented by table and barchart. Result: A total of 85 Candida species were isolated from 74 patients. Infant age (58.10%) and intensive care (64.86%) patients contributed to most of the candidemia cases. The three most common Candida species isolated during the study period were C. parapsilosis (36.9%), C. tropicalis (25%), and C. albicans (25%). Among all Candida isolates, 98.9% were susceptible to Fluconazole and Voriconazole, 99% were susceptible to Caspofungin, Micafungin, and Flucytosine, 95.7 % were susceptible to Amphotericin B. Echinocandin resistance emerged in 2020 from a C. glabrata isolate. Conclusion: The present study, conducted in a tertiary care Indonesian hospital, showed the predominance of non-albicans Candida with favorable antifungal susceptibility profiles.
{"title":"Antifungal susceptibility profile of Candida spp. causing candidemia in an Indonesian tertiary hospital","authors":"A. Wulandari, Rebriarina Hapsari, Mujahidah, Desvita Sari, Iva Puspitasari, D. Pramukarso","doi":"10.51559/jcmid.v1i2.5","DOIUrl":"https://doi.org/10.51559/jcmid.v1i2.5","url":null,"abstract":"Introduction: Invasive candidiasis has emerged as a significant public health problem in recent years, and candidemia is the most common form. Identification of the Candida species is important since some Candida species showed an increasing trend of resistance to commonly used antifungal agents. This study was conducted to describe primary demographic data and the distribution of Candida species along with their antifungal susceptibility profiles among patients with candidemia.\u0000Methods: We conducted a retrospective descriptive study on patients with candidemia and their Candida species identification and antifungal susceptibility testing (ID&AST) results at Dr. Kariadi Hospital, Indonesia, from January 2017 to December 2020. Identification and antifungal susceptibility testing of Candida species during these 4 years were determined using the Vitek-2 system. After collecting the data, it was analyzed by using SPSS 25.sav. The data was analyzed distributively, and was presented by table and barchart.\u0000Result: A total of 85 Candida species were isolated from 74 patients. Infant age (58.10%) and intensive care (64.86%) patients contributed to most of the candidemia cases. The three most common Candida species isolated during the study period were C. parapsilosis (36.9%), C. tropicalis (25%), and C. albicans (25%). Among all Candida isolates, 98.9% were susceptible to Fluconazole and Voriconazole, 99% were susceptible to Caspofungin, Micafungin, and Flucytosine, 95.7 % were susceptible to Amphotericin B. Echinocandin resistance emerged in 2020 from a C. glabrata isolate.\u0000Conclusion: The present study, conducted in a tertiary care Indonesian hospital, showed the predominance of non-albicans Candida with favorable antifungal susceptibility profiles.","PeriodicalId":11964,"journal":{"name":"European Journal of Clinical Microbiology and Infectious Diseases","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91223719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andi Meutiah Ilhamjaya, Munawir Muhammad, Ahmad Rahmat Ramadhan, R. Sjahril
Introduction: Burkholderia pseudomallei is the causative agent of melioidosis, known as Whitmore's disease, a tropical disease in humans. The bacteria can infect humans or animals, mostly found in contaminated water and soil. It spreads by direct contact with contaminated sources, inhalation or ingestion of contaminated dust or water droplets, or contact with soil through skin abrasions. Melioidosis is highly endemic in Southeast Asia and Northern Australia but rare in Makassar. Case description: A 44-year-old woman shows a red mass on the right neck, reddish, palpable, ±6x5x4mm in size, and is soft in consistency and has a cystic impression. Direct gram showed purulent mixed with blood. 24 hours after incubation under aerobic conditions, grew small colonies, smooth, cream in color, non-lactose fermenter on Mac Conkey agar. Indirect gram shows a small, gram-negative rod (safety pins appearance). The colonies were positive in the catalase and oxidase test, with citrate and urease test was negative. Burkholderia pseudomallei was identified by Vitek2 with 97% Probability. It was susceptible to doxycycline, ceftazidime, and Trimethoprim/Sulfamethoxazole. Conclusion: This is a rare finding in a clinical isolate found in Makassar. A newly emerged case, four years after the last report in Makassar. This is still a challenge to public health problems in Makassar, must be reported consistently and never lost to follow up to get proper treatment.
{"title":"A rare finding of Burkholderia pseudomallei isolate from neck abscess, 4 years after the last report in Makassar: a case report","authors":"Andi Meutiah Ilhamjaya, Munawir Muhammad, Ahmad Rahmat Ramadhan, R. Sjahril","doi":"10.51559/jcmid.v1i2.8","DOIUrl":"https://doi.org/10.51559/jcmid.v1i2.8","url":null,"abstract":"Introduction: Burkholderia pseudomallei is the causative agent of melioidosis, known as Whitmore's disease, a tropical disease in humans. The bacteria can infect humans or animals, mostly found in contaminated water and soil. It spreads by direct contact with contaminated sources, inhalation or ingestion of contaminated dust or water droplets, or contact with soil through skin abrasions. Melioidosis is highly endemic in Southeast Asia and Northern Australia but rare in Makassar.\u0000Case description: A 44-year-old woman shows a red mass on the right neck, reddish, palpable, ±6x5x4mm in size, and is soft in consistency and has a cystic impression. Direct gram showed purulent mixed with blood. 24 hours after incubation under aerobic conditions, grew small colonies, smooth, cream in color, non-lactose fermenter on Mac Conkey agar. Indirect gram shows a small, gram-negative rod (safety pins appearance). The colonies were positive in the catalase and oxidase test, with citrate and urease test was negative. Burkholderia pseudomallei was identified by Vitek2 with 97% Probability. It was susceptible to doxycycline, ceftazidime, and Trimethoprim/Sulfamethoxazole.\u0000Conclusion: This is a rare finding in a clinical isolate found in Makassar. A newly emerged case, four years after the last report in Makassar. This is still a challenge to public health problems in Makassar, must be reported consistently and never lost to follow up to get proper treatment.","PeriodicalId":11964,"journal":{"name":"European Journal of Clinical Microbiology and Infectious Diseases","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84977213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Yıldız, F. Sultanova, H. S. Özger, Merve Büyükkörük, K. Erbay, Ü. Gaygısız, A. Tufan, Ö. Gülbahar, Fatma Zehra Özcan, Nazlı Elif Kuscu, Deniz Gazioglu, Beyza Çiftçi, F. Sen, E. Senol, Kenan Hızal, Özlem Güzel Tunçcan, Pınar Aysert Yıldız, Yeşim Yıldız, M. Dizbay
Background: This study aimed to evaluate the impact of tocilizumab treatment on clinical improvement in severe COVID-19 cases and the factors affecting clinical response
背景:本研究旨在评价托珠单抗治疗对COVID-19重症患者临床改善的影响及影响临床反应的因素
{"title":"Effect of Tocilizumab Therapy On Patient Outcome In Severe COVID-19 Pneumonia","authors":"M. Yıldız, F. Sultanova, H. S. Özger, Merve Büyükkörük, K. Erbay, Ü. Gaygısız, A. Tufan, Ö. Gülbahar, Fatma Zehra Özcan, Nazlı Elif Kuscu, Deniz Gazioglu, Beyza Çiftçi, F. Sen, E. Senol, Kenan Hızal, Özlem Güzel Tunçcan, Pınar Aysert Yıldız, Yeşim Yıldız, M. Dizbay","doi":"10.36519/idcm.2021.51","DOIUrl":"https://doi.org/10.36519/idcm.2021.51","url":null,"abstract":"Background: This study aimed to evaluate the impact of tocilizumab treatment on clinical improvement in severe COVID-19 cases and the factors affecting clinical response","PeriodicalId":11964,"journal":{"name":"European Journal of Clinical Microbiology and Infectious Diseases","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74854646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Asiye Bahar Kaçmaz, P. Soysal, S. G. Tan, B. Durdu, Y. Akkoyunlu, Hamza Ogün, Fatmanur Karaköse-Okyaltırık, Sibel Bölükcü, G. Okay, Bilge Sümbül, Bedia Gülen, Ertan Sönmez, M. Meriç-Koç, R. Kazancioglu
{"title":"The effects of polypharmacy, nutritional and functional status on the progression of COVID-19 in older adults","authors":"Asiye Bahar Kaçmaz, P. Soysal, S. G. Tan, B. Durdu, Y. Akkoyunlu, Hamza Ogün, Fatmanur Karaköse-Okyaltırık, Sibel Bölükcü, G. Okay, Bilge Sümbül, Bedia Gülen, Ertan Sönmez, M. Meriç-Koç, R. Kazancioglu","doi":"10.36519/idcm.2021.60","DOIUrl":"https://doi.org/10.36519/idcm.2021.60","url":null,"abstract":"","PeriodicalId":11964,"journal":{"name":"European Journal of Clinical Microbiology and Infectious Diseases","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87068809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
As of August 21, 2021, more than 32% of the world population has received at least one dose of the COVID-19 vaccine and almost one fourth is fully vaccinated. However, only 1.4% of the population in the developing world have received at least one dose (1). While the pandemic ravages the unvaccinated communities, a new wave of the disease is emerging in countries with high rates of full vaccination status (2, 3). There may be at least three factors responsible for the latter situation: 1. Emerging new variants (e.g. delta) which are much higher contagious than their predecessors and more resistant to antibodies produced by both natural disease and the available vaccines 2. Relaxing the preventive measures (e.g. use of masks, public gatherings) in the community mostly due to initial confidence provided by vaccination 3. Waning immunity from the initial course of vaccination
{"title":"COVID-19 Vaccination in The Wake of a Fourth Wave of the Pandemic: An Evidence-Based Strategy is Desperately Needed","authors":"M. Akova","doi":"10.36519/idcm.2021.82","DOIUrl":"https://doi.org/10.36519/idcm.2021.82","url":null,"abstract":"As of August 21, 2021, more than 32% of the world population has received at least one dose of the COVID-19 vaccine and almost one fourth is fully vaccinated. However, only 1.4% of the population in the developing world have received at least one dose (1). While the pandemic ravages the unvaccinated communities, a new wave of the disease is emerging in countries with high rates of full vaccination status (2, 3). There may be at least three factors responsible for the latter situation: 1. Emerging new variants (e.g. delta) which are much higher contagious than their predecessors and more resistant to antibodies produced by both natural disease and the available vaccines 2. Relaxing the preventive measures (e.g. use of masks, public gatherings) in the community mostly due to initial confidence provided by vaccination 3. Waning immunity from the initial course of vaccination","PeriodicalId":11964,"journal":{"name":"European Journal of Clinical Microbiology and Infectious Diseases","volume":"101 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85868496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Yapar, Özlem Akdoğan, Murat Kendirci, Aysel Kocagül Çelikbaş, N. Baykam
{"title":"Diabetic Foot Infections and Outcomes: A Single Center Study","authors":"D. Yapar, Özlem Akdoğan, Murat Kendirci, Aysel Kocagül Çelikbaş, N. Baykam","doi":"10.36519/idcm.2021.62","DOIUrl":"https://doi.org/10.36519/idcm.2021.62","url":null,"abstract":"","PeriodicalId":11964,"journal":{"name":"European Journal of Clinical Microbiology and Infectious Diseases","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90970321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ç. Erol, Tugba Yanik-Yalcin, N. Sarı, Özlem Azap Kurt, H. Arslan
,
,
{"title":"Predictors of COVID-19 among Healthcare Workers who were Exposed to COVID-19","authors":"Ç. Erol, Tugba Yanik-Yalcin, N. Sarı, Özlem Azap Kurt, H. Arslan","doi":"10.36519/idcm.2021.74","DOIUrl":"https://doi.org/10.36519/idcm.2021.74","url":null,"abstract":",","PeriodicalId":11964,"journal":{"name":"European Journal of Clinical Microbiology and Infectious Diseases","volume":"89 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74644550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}