Ş. Keske, Bahar Madran, A. Yerlikaya, Gözde Akbaba, Ebru Dönmez, Y. Beşli, Ö. Ergönül
{"title":"The role of Isolation of the Patients on Hospital Admission for Prevention of Nosocomial Infections","authors":"Ş. Keske, Bahar Madran, A. Yerlikaya, Gözde Akbaba, Ebru Dönmez, Y. Beşli, Ö. Ergönül","doi":"10.36519/idcm.2021.35","DOIUrl":"https://doi.org/10.36519/idcm.2021.35","url":null,"abstract":"","PeriodicalId":11964,"journal":{"name":"European Journal of Clinical Microbiology and Infectious Diseases","volume":"55 1","pages":"8-13"},"PeriodicalIF":0.0,"publicationDate":"2021-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77280223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aral Sürmeli, Öykü Beyaz, Elif Sitre Koç, Yasemin Gündoğdu, Ç. Çuhadaroglu, S. Kocagöz
{"title":"Presenting Characteristics and ICU Admission Among Patients Hospitalized with COVID-19","authors":"Aral Sürmeli, Öykü Beyaz, Elif Sitre Koç, Yasemin Gündoğdu, Ç. Çuhadaroglu, S. Kocagöz","doi":"10.36519/idcm.2021.20","DOIUrl":"https://doi.org/10.36519/idcm.2021.20","url":null,"abstract":"","PeriodicalId":11964,"journal":{"name":"European Journal of Clinical Microbiology and Infectious Diseases","volume":"1 1","pages":"14-21"},"PeriodicalIF":0.0,"publicationDate":"2021-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80641684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Alkan, Emine Kübra Dindar Demiray, E. Yıldız, C. Özlü
{"title":"Analysis of Scientific Publications on Acinetobacter bacteremia in Web of Science","authors":"S. Alkan, Emine Kübra Dindar Demiray, E. Yıldız, C. Özlü","doi":"10.36519/idcm.2021.37","DOIUrl":"https://doi.org/10.36519/idcm.2021.37","url":null,"abstract":"","PeriodicalId":11964,"journal":{"name":"European Journal of Clinical Microbiology and Infectious Diseases","volume":"109 1","pages":"39-44"},"PeriodicalIF":0.0,"publicationDate":"2021-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76521836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Coronaviruses are known to evolve slower than the other RNA viruses; however, SARS-CoV-2 underwent a major shift through D614G change in February 2020, even before the declaration of a pandemic by WHO and D614G variant became rapidly dominant throughout the world. The spike protein of this variant with D614G change have a higher affinity to human ACE-2 and gained a transmission advantage against other circulating variants. Some mutations may confer advantages for the virus, and the variants carrying this kind of mutations may outcompete the previous variants (1). A mutation may cause changes in biology, transmissibility, susceptibility of the virus against naturally or vaccine-induced immunity, and the presentation and outcome of the disease caused by the virus. All of these changes may pose extra challenges regarding the containment of the epidemic, treatment and prevention of the disease using antivirals, immunotherapeutics like monoclonal antibodies or convalescent plasma, and vaccines (2,3).
{"title":"The Impact of SARS-CoV-2 Variants on Morbidity, Mortality and Effectiveness of Vaccines","authors":"K. Midilli","doi":"10.36519/idcm.2020.0044","DOIUrl":"https://doi.org/10.36519/idcm.2020.0044","url":null,"abstract":"Coronaviruses are known to evolve slower than the other RNA viruses; however, SARS-CoV-2 underwent a major shift through D614G change in February 2020, even before the declaration of a pandemic by WHO and D614G variant became rapidly dominant throughout the world. The spike protein of this variant with D614G change have a higher affinity to human ACE-2 and gained a transmission advantage against other circulating variants. Some mutations may confer advantages for the virus, and the variants carrying this kind of mutations may outcompete the previous variants (1). A mutation may cause changes in biology, transmissibility, susceptibility of the virus against naturally or vaccine-induced immunity, and the presentation and outcome of the disease caused by the virus. All of these changes may pose extra challenges regarding the containment of the epidemic, treatment and prevention of the disease using antivirals, immunotherapeutics like monoclonal antibodies or convalescent plasma, and vaccines (2,3).","PeriodicalId":11964,"journal":{"name":"European Journal of Clinical Microbiology and Infectious Diseases","volume":"23 1","pages":"48-51"},"PeriodicalIF":0.0,"publicationDate":"2021-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85938099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Şimşek-Yavuz, Sibel Dogan–Kaya, Denef Deniz, Elif Tükenmez-Tigen, S. Öztürk, Ş. Menekşe, M. Öcalmaz, S. Başaran, Ayfer Sensoy, Yeşim Uygun Kızmaz, Ezgi Yılmaz, H. Eraksoy
Objective: A simple and widely available test is needed to monitor the response to the treatment and predict adverse outcomes in patients with infective endocarditis (IE). We aimed to detect the role of C-reactive protein (CRP) level in the prognosis of IE. Materials and Methods: The patients diagnosed as probable or definite IE between 2015 and 2016 from five medical centers were included in the study. Clinical and laboratory features of the patients recorded on previously prepared forms retrospectively. Comparison of CRP levels between survived and dead patients were made by repeated-measures variance analysis. Receiver operating characteristic (ROC) curves at baseline, the first, second, third and fourth week of antimicrobial treatment were constructed to explain the ability of CRP level to predict mortality. Multivariate analysis was performed to predict the risk factors for mortality. Results: In total, 111 cases of IE were included. Serum CRP levels were higher in patients with mortality at every measurement. Comparing baseline CRP, lower than a double or triple decrease of serum CRP level at the third or fourth week of treatment or any increase under treatment were related to mortality. According to the ROC curve analysis, the highest overall accuracy in death prediction was at the fourth week CRP level (c=0.74); the CRP level of ≥50 mg/L was 86% sensitive and 78% specific to predict mortality. The presence of chronic renal failure (OR 14.386) and the fourth week CRP level (OR 1.016) were independent risk factors in terms of mortality. Conclusion: Being an easily performed and widely available test, CRP is a useful tool to follow up the response to the treatment and predict outcome among patients with IE. In the fourth week of treatment, a CRP level of ≥50 mg/L should be regarded as an alarming sign of poor outcome and should lead to investigation and appropriate management of complications.
{"title":"The Impact of C Reactive Protein in Prediction of the Outcome in Infective Endocarditis","authors":"S. Şimşek-Yavuz, Sibel Dogan–Kaya, Denef Deniz, Elif Tükenmez-Tigen, S. Öztürk, Ş. Menekşe, M. Öcalmaz, S. Başaran, Ayfer Sensoy, Yeşim Uygun Kızmaz, Ezgi Yılmaz, H. Eraksoy","doi":"10.36519/idcm.2021.42","DOIUrl":"https://doi.org/10.36519/idcm.2021.42","url":null,"abstract":"Objective: A simple and widely available test is needed to monitor the response to the treatment and predict adverse outcomes in patients with infective endocarditis (IE). We aimed to detect the role of C-reactive protein (CRP) level in the prognosis of IE. Materials and Methods: The patients diagnosed as probable or definite IE between 2015 and 2016 from five medical centers were included in the study. Clinical and laboratory features of the patients recorded on previously prepared forms retrospectively. Comparison of CRP levels between survived and dead patients were made by repeated-measures variance analysis. Receiver operating characteristic (ROC) curves at baseline, the first, second, third and fourth week of antimicrobial treatment were constructed to explain the ability of CRP level to predict mortality. Multivariate analysis was performed to predict the risk factors for mortality. Results: In total, 111 cases of IE were included. Serum CRP levels were higher in patients with mortality at every measurement. Comparing baseline CRP, lower than a double or triple decrease of serum CRP level at the third or fourth week of treatment or any increase under treatment were related to mortality. According to the ROC curve analysis, the highest overall accuracy in death prediction was at the fourth week CRP level (c=0.74); the CRP level of ≥50 mg/L was 86% sensitive and 78% specific to predict mortality. The presence of chronic renal failure (OR 14.386) and the fourth week CRP level (OR 1.016) were independent risk factors in terms of mortality. Conclusion: Being an easily performed and widely available test, CRP is a useful tool to follow up the response to the treatment and predict outcome among patients with IE. In the fourth week of treatment, a CRP level of ≥50 mg/L should be regarded as an alarming sign of poor outcome and should lead to investigation and appropriate management of complications.","PeriodicalId":11964,"journal":{"name":"European Journal of Clinical Microbiology and Infectious Diseases","volume":"1 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2021-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88532733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
One of the uncommon and often missed causes of acute pancytopenia is tick-borne illnesses, mainly Human Monocytic Ehrlichiosis (HME) / Human Granulocytic Anaplasmosis (HGA) and Babesiosis, though the specific mechanism of the former is still unknown. The challenges in such diagnosis are that the tests for many tick-borne diseases have poor validity, and also that these diseases can co-exist, making the exact etiology of the hematopoietic defect more difficult to identify. This report demonstrates a case of acute pancytopenia secondary to tick-borne illness, which is a rare presentation. This was based on the exposure history, exclusion of other causes, Erythema Migrans lesion, response to doxycycline, and the known limitations of testing. A 60-year-old Caucasian female with Rheumatoid arthritis, presented in Rochester, New York during summer, with a six-day history of vague symptoms including fatigue, headache, poor appetite, and nausea. She was frequently visiting her husband who lives in a cabin in a near wooded area. Records showed she had a history of Lyme disease that got successfully treated one year prior, but did not recall any tick bites lately. She was found to have fever, acute pancytopenia, and transaminitis. Her initial labs also showed high LDH and CRP. Otherwise, Reticulocytes, Vitamin B12, Folate, Lactic acid, have all been normal, as well as her imaging including chest X-ray, head CT, and abdominal ultrasound. A bone marrow aspirate showed nonspecific reactive changes. Infectious diseases team later noted a circular skin lesion with pale center suggesting Erythema Migrans, with a thorough workup only positive for Lyme IgG and EBV IgG, but negative for Legionella antigen, Leptospirosis antibody, HIV, Parvovirus B19, Hepatitis panel, HME/HGA testing, blood smear, and blood cultures. She was started on a Doxycycline trial on Day 4 for probable tick-borne illness with rapid improvement in her symptoms and lab results.
{"title":"Tick Borne Disease Induced Pancytopenia","authors":"Mina Said","doi":"10.36519/idcm.2021.32","DOIUrl":"https://doi.org/10.36519/idcm.2021.32","url":null,"abstract":"One of the uncommon and often missed causes of acute pancytopenia is tick-borne illnesses, mainly Human Monocytic Ehrlichiosis (HME) / Human Granulocytic Anaplasmosis (HGA) and Babesiosis, though the specific mechanism of the former is still unknown. The challenges in such diagnosis are that the tests for many tick-borne diseases have poor validity, and also that these diseases can co-exist, making the exact etiology of the hematopoietic defect more difficult to identify. This report demonstrates a case of acute pancytopenia secondary to tick-borne illness, which is a rare presentation. This was based on the exposure history, exclusion of other causes, Erythema Migrans lesion, response to doxycycline, and the known limitations of testing. A 60-year-old Caucasian female with Rheumatoid arthritis, presented in Rochester, New York during summer, with a six-day history of vague symptoms including fatigue, headache, poor appetite, and nausea. She was frequently visiting her husband who lives in a cabin in a near wooded area. Records showed she had a history of Lyme disease that got successfully treated one year prior, but did not recall any tick bites lately. She was found to have fever, acute pancytopenia, and transaminitis. Her initial labs also showed high LDH and CRP. Otherwise, Reticulocytes, Vitamin B12, Folate, Lactic acid, have all been normal, as well as her imaging including chest X-ray, head CT, and abdominal ultrasound. A bone marrow aspirate showed nonspecific reactive changes. Infectious diseases team later noted a circular skin lesion with pale center suggesting Erythema Migrans, with a thorough workup only positive for Lyme IgG and EBV IgG, but negative for Legionella antigen, Leptospirosis antibody, HIV, Parvovirus B19, Hepatitis panel, HME/HGA testing, blood smear, and blood cultures. She was started on a Doxycycline trial on Day 4 for probable tick-borne illness with rapid improvement in her symptoms and lab results.","PeriodicalId":11964,"journal":{"name":"European Journal of Clinical Microbiology and Infectious Diseases","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89245032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-31DOI: 10.36519/idcm.2020.003010.36519/
I. Kayı, Gokcen Yavas, B. Uçurum, P. Yilmaz, Betul Gokcek, Seyda Ece Oguzer, Bugse Eglenen
This work is licensed under a Creative Commons Attribution-Non Commercial 4.0 International License. ABSTRACT Introduction: Human Papilloma Virus (HPV) vaccine provides a primary prevention opportunity to decrease the morbidity and mortality of cervical cancer. Turkey has not yet included it in the national immunization program, but it is commercially available. We aimed to explore the predictors of HPV vaccine uptake among female students in a university in Turkey. Methods: This is a cross-sectional survey conducted with 1,115 female students via a questionnaire assessing the sociodemographic characteristics, vaccination uptake, knowledge and attitudes towards HPV and related conditions. Results: 75.2% (n=838) of the participants reported hearing HPV vaccine and 17.9% (n=200) reported they had received at least one dose of HPV vaccine. The median knowledge score was 6 out of 10. Multivariate analysis showed that age (OR: 1.181; 95% CI 1.070-1.304), knowledge score (OR: 1.183; 95% CI 1.075-1.302), department (OR: 1.667; 95% CI 1.0872.557), sexual activity (OR: 2.384; 95% CI 1.596-3.561), and level of family income (OR: 3.205; 95% CI 2.066-4.970), were significantly associated with vaccination uptake. Conclusion: Our study indicates that the cost of HPV vaccines is an important barrier to equitable access to vaccines. Policies ensuring equitable access and raising awareness has the potential to promote the vaccination uptake among youth.
本作品采用知识共享署名-非商业4.0国际许可协议。摘要简介:人乳头瘤病毒(HPV)疫苗为降低宫颈癌的发病率和死亡率提供了一级预防机会。土耳其尚未将其纳入国家免疫规划，但可以在市场上买到。我们的目的是探讨土耳其一所大学女学生HPV疫苗接种的预测因素。方法:对1115名女大学生进行横断面调查，采用问卷调查的方式评估社会人口学特征、疫苗接种率、对HPV及相关疾病的知识和态度。结果:75.2% (n=838)的参与者报告听过HPV疫苗，17.9% (n=200)的参与者报告他们至少接种过一剂HPV疫苗。知识得分中位数为6分(满分为10分)。多因素分析显示，年龄(OR: 1.181;95% CI 1.070-1.304)，知识评分(OR: 1.183;95% CI 1.075-1.302)，科室(OR: 1.667;95% CI 1.0872.557)，性行为(OR: 2.384;95% CI 1.596-3.561)和家庭收入水平(OR: 3.205;95%可信区间为2.066-4.970)，与疫苗接种率显著相关。结论:我们的研究表明，HPV疫苗的成本是公平获得疫苗的一个重要障碍。确保公平获取和提高认识的政策有可能促进青年接种疫苗。
{"title":"Predictors of Human Papilloma Virus Vaccination Uptake among Female University\u0000Students in Turkey","authors":"I. Kayı, Gokcen Yavas, B. Uçurum, P. Yilmaz, Betul Gokcek, Seyda Ece Oguzer, Bugse Eglenen","doi":"10.36519/idcm.2020.003010.36519/","DOIUrl":"https://doi.org/10.36519/idcm.2020.003010.36519/","url":null,"abstract":"This work is licensed under a Creative Commons Attribution-Non Commercial 4.0 International License. ABSTRACT Introduction: Human Papilloma Virus (HPV) vaccine provides a primary prevention opportunity to decrease the morbidity and mortality of cervical cancer. Turkey has not yet included it in the national immunization program, but it is commercially available. We aimed to explore the predictors of HPV vaccine uptake among female students in a university in Turkey. Methods: This is a cross-sectional survey conducted with 1,115 female students via a questionnaire assessing the sociodemographic characteristics, vaccination uptake, knowledge and attitudes towards HPV and related conditions. Results: 75.2% (n=838) of the participants reported hearing HPV vaccine and 17.9% (n=200) reported they had received at least one dose of HPV vaccine. The median knowledge score was 6 out of 10. Multivariate analysis showed that age (OR: 1.181; 95% CI 1.070-1.304), knowledge score (OR: 1.183; 95% CI 1.075-1.302), department (OR: 1.667; 95% CI 1.0872.557), sexual activity (OR: 2.384; 95% CI 1.596-3.561), and level of family income (OR: 3.205; 95% CI 2.066-4.970), were significantly associated with vaccination uptake. Conclusion: Our study indicates that the cost of HPV vaccines is an important barrier to equitable access to vaccines. Policies ensuring equitable access and raising awareness has the potential to promote the vaccination uptake among youth.","PeriodicalId":11964,"journal":{"name":"European Journal of Clinical Microbiology and Infectious Diseases","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76789517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-31DOI: 10.36519/10.36519/idcm.2020.0024
Uğur Kesimal
This work is licensed under a Creative Commons Attribution-Non Commercial 4.0 International License. A40-year-old female patient without any medical history presented to the emergency department with a 3-day history of neck pain and headache. She did not show any other symptoms. Her initial laboratory tests showed slightly increased C-reactive protein (6 mg/L; normal range 0-5 mg/L) and a normal white cell count. There were not observed any other abnormal laboratory finding (leukocyte, 7.4 x 103/uL; hemoglobin, 11.7 gr/dL; platelet, 172 x 103/uL; aspartate aminotransferase, 27 U/L; alanine aminotransferase, 31 U/L). After her neurological examinations, she
{"title":"A COVID-19 Patient Which is Diagnosed after Magnetic Resonance Imaging","authors":"Uğur Kesimal","doi":"10.36519/10.36519/idcm.2020.0024","DOIUrl":"https://doi.org/10.36519/10.36519/idcm.2020.0024","url":null,"abstract":"This work is licensed under a Creative Commons Attribution-Non Commercial 4.0 International License. A40-year-old female patient without any medical history presented to the emergency department with a 3-day history of neck pain and headache. She did not show any other symptoms. Her initial laboratory tests showed slightly increased C-reactive protein (6 mg/L; normal range 0-5 mg/L) and a normal white cell count. There were not observed any other abnormal laboratory finding (leukocyte, 7.4 x 103/uL; hemoglobin, 11.7 gr/dL; platelet, 172 x 103/uL; aspartate aminotransferase, 27 U/L; alanine aminotransferase, 31 U/L). After her neurological examinations, she","PeriodicalId":11964,"journal":{"name":"European Journal of Clinical Microbiology and Infectious Diseases","volume":"2015 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87168754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Hydroxychloroquine (HQN) and azithromycin (AZ) were used in the treatment of coronavirus disease 2019 (Covid-19), which might lead to cardiac side effects. Aim: We aimed to describe the safety of HQN and HQN+AZ in terms of cardiac events. Materials and methods: The QTc intervals were calculated by examining the ecg records of the first day and fifth day of hospitalization the patients who received HQN with or without concominant AZ for treatment of Covid 19. Results: We included 93 patients.Moderate QTc prolongation was detected in 3 (7.5%) of 40 patients who received hydroxychloroquine monotherapy for five days. Critical qtc prolongation was not detected in any patient. Three (5.6%) of 53 patients who received dual treatments had moderate QTc prolongation and two patients had critical qtc prolongation. Torsades de pointes was not detected among the patients. Conclusion: Close ECG monitoring is necessary, and the frequency of ECG monitorization should be individualized in patients receiving azithromycin with hydroxychloroquine.
{"title":"Adverse Cardiac Events Among the Patients Using Hydroxychloroquine and Azithromycin in COVID-19","authors":"Ibrahim Ethem Dural, Y. Nadir","doi":"10.36519/idcm.2020.0023","DOIUrl":"https://doi.org/10.36519/idcm.2020.0023","url":null,"abstract":"Background: Hydroxychloroquine (HQN) and azithromycin (AZ) were used in the treatment of coronavirus disease 2019 (Covid-19), which might lead to cardiac side effects. Aim: We aimed to describe the safety of HQN and HQN+AZ in terms of cardiac events. Materials and methods: The QTc intervals were calculated by examining the ecg records of the first day and fifth day of hospitalization the patients who received HQN with or without concominant AZ for treatment of Covid 19. Results: We included 93 patients.Moderate QTc prolongation was detected in 3 (7.5%) of 40 patients who received hydroxychloroquine monotherapy for five days. Critical qtc prolongation was not detected in any patient. Three (5.6%) of 53 patients who received dual treatments had moderate QTc prolongation and two patients had critical qtc prolongation. Torsades de pointes was not detected among the patients. Conclusion: Close ECG monitoring is necessary, and the frequency of ECG monitorization should be individualized in patients receiving azithromycin with hydroxychloroquine.","PeriodicalId":11964,"journal":{"name":"European Journal of Clinical Microbiology and Infectious Diseases","volume":"69 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80888183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Striking Observations on Two Personal Protective Measures During COVID-19 Pandemic: Face Mask and Social Distance","authors":"S. Kose, Y. Ozbel","doi":"10.36519/idcm.2020.0022","DOIUrl":"https://doi.org/10.36519/idcm.2020.0022","url":null,"abstract":"","PeriodicalId":11964,"journal":{"name":"European Journal of Clinical Microbiology and Infectious Diseases","volume":"45 2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80012147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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