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Photon-counting computed tomography: a revolution in cardiac imaging. 光子计数计算机断层扫描:心脏成像的革命。
IF 39.3 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-01-21 DOI: 10.1093/eurheartj/ehaf1118
Gianluca Pontone,Saima Mushtaq,Carmine Pizzi,Pál Maurovich-Horvat,Jonathon Leipsic,Patrick W Serruys
Photon-counting detector computed tomography (PCD-CT) is an emerging advanced CT technology that differs from conventional energy-integrating detector CT (EID-CT) scanners in its ability to directly convert incident X-ray photon energies into electrical signals. Since its commercial market introduction in 2021, several studies have identified advantages of this new technology in the field of cardiovascular imaging, including improved image quality due to an enhanced contrast-to-noise ratio, superior spatial resolution, reduced artefacts, and a reduced radiation dose. Nonetheless, radiation exposure with PCD-CT can vary depending on the acquisition mode and protocol used, highlighting the importance of tailored optimization in clinical practice. In particular, this new technology appears feasible in patients with a high plaque burden independent of morphology, unravelling new phenotypes of plaque, in patients with stents due to the improved visualization of the coronary in-stent lumen, potentially expanding the scope of CT. Early studies and clinical experience support these potential applications of PCD-CT in cardiovascular diagnostics, suggesting workflow optimization and improved patient management. In this review, the authors aim to describe the role of PCD-CT not only in the exclusion of coronary artery disease, grading of coronary stenosis and plaque imaging, but also in evaluation of cardiac chambers and myocardium for tissue characterization trying to understand whether PCD-CT has yet led to a true revolution and significant progress in cardiovascular imaging.
光子计数检测器计算机断层扫描(PCD-CT)是一种新兴的先进CT技术,不同于传统的能量积分检测器CT (EID-CT)扫描仪,它能够将入射的x射线光子能量直接转换为电信号。自2021年推出商业市场以来,多项研究已经确定了这项新技术在心血管成像领域的优势,包括由于增强的对比度与噪声比、优越的空间分辨率、减少的伪像和降低的辐射剂量而提高的图像质量。尽管如此,PCD-CT的辐射暴露可能因采集模式和使用的方案而异,这突出了临床实践中量身定制优化的重要性。特别是,这项新技术在斑块负担高且不依赖于形态学的患者中似乎是可行的,在支架患者中,由于冠状动脉支架内腔的可视化改善,揭示了新的斑块表型,潜在地扩大了CT的范围。早期研究和临床经验支持了PCD-CT在心血管诊断中的潜在应用,建议优化工作流程和改善患者管理。在这篇综述中,作者的目的是描述PCD-CT不仅在冠状动脉疾病的排除、冠状动脉狭窄的分级和斑块成像方面的作用,而且在评估心室和心肌组织特征方面的作用,试图了解PCD-CT是否已经导致了心血管成像的真正革命和重大进展。
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引用次数: 0
Limitations of current animal models in atherosclerosis: an integrative multiomics perspective. 当前动脉粥样硬化动物模型的局限性:综合多组学视角。
IF 39.3 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-01-20 DOI: 10.1093/eurheartj/ehaf997
Dimitris Kardassis,Núria Amigó,Tijana Mitić
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引用次数: 0
Environmental stressors and cardiovascular health: acting locally for global impact in a changing world. 环境压力源和心血管健康:在不断变化的世界中为全球影响采取地方行动。
IF 39.3 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-01-20 DOI: 10.1093/eurheartj/ehaf915
Thomas Münzel,Thomas Lüscher,Christopher M Kramer,Keith Churchwell,Amam Mbakwem,Sanjay Rajagopalan
Non-communicable diseases (NCDs) account for 70% of global mortality and are responsible for over 38 million deaths annually, with cardiovascular disease (CVD) constituting most of these fatalities. While traditional risk factors for CVD have long been recognized, there is growing evidence that a rising prevalence of ubiquitous environmental risk factors (ERFs) may play an increasingly significant role in the genesis and rising prevalence of NCDs. ERFs include many interconnected anthropogenic exposures with cumulative compound health impacts, including air pollution, noise exposure, artificial light at night, plastic pollution, chemical pollution and the various effects of climate change, such as heat extremes, desert storms, floods and wildfires. Urbanization has intensified the impact of many ERFs and created intense exposure environments, highlighting the urgency and the opportunity to address these for maximum public health benefit. Impactful intervention often requires regulatory and policy-driven efforts addressing the genesis of exposures and minimizes their health impact, particularly in vulnerable populations who may contribute the least but may be impacted the most. Solutions must involve the development of resiliency and adaptation measures to a changing world, where the probability of sudden catastrophic and cascading events is much more likely. Political will and international cooperation are essential in establishing and enforcing regulations that promote cleaner air and water, quieter and natural biodiverse environments, and sustainable infrastructure in urban, and rural medical facilities. Integration of planetary and environmental health into cardiovascular care will be vital in reducing the burden of NCDs globally. By addressing the root causes of environmental stressors, it is possible to reduce the incidence of CVDs and promote healthier, just and sustainable societies.
非传染性疾病(NCDs)占全球死亡率的70%,每年造成3800多万人死亡,其中心血管疾病(CVD)占大多数。虽然心血管疾病的传统风险因素早已被认识到,但越来越多的证据表明,无处不在的环境风险因素(ERFs)的患病率上升可能在非传染性疾病的发生和患病率上升中起着越来越重要的作用。环境影响因子包括许多相互关联的、具有累积复合健康影响的人为暴露,包括空气污染、噪音暴露、夜间人造光、塑料污染、化学污染以及极端高温、沙漠风暴、洪水和野火等气候变化的各种影响。城市化加剧了许多环境影响因子的影响,造成了高度暴露的环境,突出了解决这些问题的紧迫性和机会,以最大限度地造福公众健康。有效的干预措施往往需要监管和政策驱动的努力,解决接触的根源,并尽量减少其对健康的影响,特别是对危害最小但可能受影响最大的弱势群体。解决方案必须包括制定弹性和适应措施,以适应不断变化的世界,在这个世界中,突然发生灾难性和连锁事件的可能性要大得多。政治意愿和国际合作对于制定和执行促进更清洁的空气和水、更安静和自然的生物多样性环境以及城市和农村医疗设施的可持续基础设施的法规至关重要。将地球和环境卫生纳入心血管保健对于减轻全球非传染性疾病负担至关重要。通过解决环境压力源的根本原因,就有可能减少心血管疾病的发病率,并促进更健康、公正和可持续的社会。
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引用次数: 0
Challenges and improvements in the study of live zoster vaccination's impact on cardiovascular health. 带状疱疹活疫苗接种对心血管健康影响研究中的挑战和改进。
IF 35.6 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-01-16 DOI: 10.1093/eurheartj/ehaf857
Bin He, Jun Li
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引用次数: 0
Weekly Journal Scan: spironolactone does not ACHIEVE reduction of cardiovascular outcomes in dialysis patients. 周刊扫描:螺内酯不能降低透析患者的心血管结局。
IF 35.6 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-01-16 DOI: 10.1093/eurheartj/ehaf797
Daniela Pedicino, Carlo Patrono
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引用次数: 0
The year in cardiovascular medicine 2025: the top 10 papers in heart failure. 心血管医学2025年:心力衰竭十大论文。
IF 35.6 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-01-16 DOI: 10.1093/eurheartj/ehaf1044
Johann Bauersachs, Shelley Zieroth, Rudolf A de Boer
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引用次数: 0
EHRA practical compendium of antiarrhythmic drugs: 10 key messages on contemporary use. EHRA抗心律失常药物实用纲要:当代使用的10个关键信息。
IF 35.6 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-01-16 DOI: 10.1093/eurheartj/ehaf805
Jose L Merino, James A Reiffel, A John Camm
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引用次数: 0
Quiet flames: inflammation without traditional risk factors. 安静的火焰:没有传统危险因素的炎症。
IF 35.6 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-01-16 DOI: 10.1093/eurheartj/ehaf653
Natalie Arnold, Wolfgang Koenig
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引用次数: 0
Heart failure: terminology matters. 心力衰竭:术语很重要。
IF 35.6 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-01-16 DOI: 10.1093/eurheartj/ehaf775
Hajar Habibi, Michael A Gatzoulis, Margarita Brida
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引用次数: 0
Improving prevention: traditional and non-traditional risk factors. 改进预防:传统和非传统风险因素。
IF 39.3 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-01-16 DOI: 10.1093/eurheartj/ehaf1092
Filippo Crea
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引用次数: 0
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European Heart Journal
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