Pub Date : 2026-01-21DOI: 10.1093/eurheartj/ehaf1118
Gianluca Pontone,Saima Mushtaq,Carmine Pizzi,Pál Maurovich-Horvat,Jonathon Leipsic,Patrick W Serruys
Photon-counting detector computed tomography (PCD-CT) is an emerging advanced CT technology that differs from conventional energy-integrating detector CT (EID-CT) scanners in its ability to directly convert incident X-ray photon energies into electrical signals. Since its commercial market introduction in 2021, several studies have identified advantages of this new technology in the field of cardiovascular imaging, including improved image quality due to an enhanced contrast-to-noise ratio, superior spatial resolution, reduced artefacts, and a reduced radiation dose. Nonetheless, radiation exposure with PCD-CT can vary depending on the acquisition mode and protocol used, highlighting the importance of tailored optimization in clinical practice. In particular, this new technology appears feasible in patients with a high plaque burden independent of morphology, unravelling new phenotypes of plaque, in patients with stents due to the improved visualization of the coronary in-stent lumen, potentially expanding the scope of CT. Early studies and clinical experience support these potential applications of PCD-CT in cardiovascular diagnostics, suggesting workflow optimization and improved patient management. In this review, the authors aim to describe the role of PCD-CT not only in the exclusion of coronary artery disease, grading of coronary stenosis and plaque imaging, but also in evaluation of cardiac chambers and myocardium for tissue characterization trying to understand whether PCD-CT has yet led to a true revolution and significant progress in cardiovascular imaging.
{"title":"Photon-counting computed tomography: a revolution in cardiac imaging.","authors":"Gianluca Pontone,Saima Mushtaq,Carmine Pizzi,Pál Maurovich-Horvat,Jonathon Leipsic,Patrick W Serruys","doi":"10.1093/eurheartj/ehaf1118","DOIUrl":"https://doi.org/10.1093/eurheartj/ehaf1118","url":null,"abstract":"Photon-counting detector computed tomography (PCD-CT) is an emerging advanced CT technology that differs from conventional energy-integrating detector CT (EID-CT) scanners in its ability to directly convert incident X-ray photon energies into electrical signals. Since its commercial market introduction in 2021, several studies have identified advantages of this new technology in the field of cardiovascular imaging, including improved image quality due to an enhanced contrast-to-noise ratio, superior spatial resolution, reduced artefacts, and a reduced radiation dose. Nonetheless, radiation exposure with PCD-CT can vary depending on the acquisition mode and protocol used, highlighting the importance of tailored optimization in clinical practice. In particular, this new technology appears feasible in patients with a high plaque burden independent of morphology, unravelling new phenotypes of plaque, in patients with stents due to the improved visualization of the coronary in-stent lumen, potentially expanding the scope of CT. Early studies and clinical experience support these potential applications of PCD-CT in cardiovascular diagnostics, suggesting workflow optimization and improved patient management. In this review, the authors aim to describe the role of PCD-CT not only in the exclusion of coronary artery disease, grading of coronary stenosis and plaque imaging, but also in evaluation of cardiac chambers and myocardium for tissue characterization trying to understand whether PCD-CT has yet led to a true revolution and significant progress in cardiovascular imaging.","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":"6 1","pages":""},"PeriodicalIF":39.3,"publicationDate":"2026-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146015009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-20DOI: 10.1093/eurheartj/ehaf997
Dimitris Kardassis,Núria Amigó,Tijana Mitić
{"title":"Limitations of current animal models in atherosclerosis: an integrative multiomics perspective.","authors":"Dimitris Kardassis,Núria Amigó,Tijana Mitić","doi":"10.1093/eurheartj/ehaf997","DOIUrl":"https://doi.org/10.1093/eurheartj/ehaf997","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":"101 1","pages":""},"PeriodicalIF":39.3,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146005223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-20DOI: 10.1093/eurheartj/ehaf915
Thomas Münzel,Thomas Lüscher,Christopher M Kramer,Keith Churchwell,Amam Mbakwem,Sanjay Rajagopalan
Non-communicable diseases (NCDs) account for 70% of global mortality and are responsible for over 38 million deaths annually, with cardiovascular disease (CVD) constituting most of these fatalities. While traditional risk factors for CVD have long been recognized, there is growing evidence that a rising prevalence of ubiquitous environmental risk factors (ERFs) may play an increasingly significant role in the genesis and rising prevalence of NCDs. ERFs include many interconnected anthropogenic exposures with cumulative compound health impacts, including air pollution, noise exposure, artificial light at night, plastic pollution, chemical pollution and the various effects of climate change, such as heat extremes, desert storms, floods and wildfires. Urbanization has intensified the impact of many ERFs and created intense exposure environments, highlighting the urgency and the opportunity to address these for maximum public health benefit. Impactful intervention often requires regulatory and policy-driven efforts addressing the genesis of exposures and minimizes their health impact, particularly in vulnerable populations who may contribute the least but may be impacted the most. Solutions must involve the development of resiliency and adaptation measures to a changing world, where the probability of sudden catastrophic and cascading events is much more likely. Political will and international cooperation are essential in establishing and enforcing regulations that promote cleaner air and water, quieter and natural biodiverse environments, and sustainable infrastructure in urban, and rural medical facilities. Integration of planetary and environmental health into cardiovascular care will be vital in reducing the burden of NCDs globally. By addressing the root causes of environmental stressors, it is possible to reduce the incidence of CVDs and promote healthier, just and sustainable societies.
{"title":"Environmental stressors and cardiovascular health: acting locally for global impact in a changing world.","authors":"Thomas Münzel,Thomas Lüscher,Christopher M Kramer,Keith Churchwell,Amam Mbakwem,Sanjay Rajagopalan","doi":"10.1093/eurheartj/ehaf915","DOIUrl":"https://doi.org/10.1093/eurheartj/ehaf915","url":null,"abstract":"Non-communicable diseases (NCDs) account for 70% of global mortality and are responsible for over 38 million deaths annually, with cardiovascular disease (CVD) constituting most of these fatalities. While traditional risk factors for CVD have long been recognized, there is growing evidence that a rising prevalence of ubiquitous environmental risk factors (ERFs) may play an increasingly significant role in the genesis and rising prevalence of NCDs. ERFs include many interconnected anthropogenic exposures with cumulative compound health impacts, including air pollution, noise exposure, artificial light at night, plastic pollution, chemical pollution and the various effects of climate change, such as heat extremes, desert storms, floods and wildfires. Urbanization has intensified the impact of many ERFs and created intense exposure environments, highlighting the urgency and the opportunity to address these for maximum public health benefit. Impactful intervention often requires regulatory and policy-driven efforts addressing the genesis of exposures and minimizes their health impact, particularly in vulnerable populations who may contribute the least but may be impacted the most. Solutions must involve the development of resiliency and adaptation measures to a changing world, where the probability of sudden catastrophic and cascading events is much more likely. Political will and international cooperation are essential in establishing and enforcing regulations that promote cleaner air and water, quieter and natural biodiverse environments, and sustainable infrastructure in urban, and rural medical facilities. Integration of planetary and environmental health into cardiovascular care will be vital in reducing the burden of NCDs globally. By addressing the root causes of environmental stressors, it is possible to reduce the incidence of CVDs and promote healthier, just and sustainable societies.","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":"39 1","pages":""},"PeriodicalIF":39.3,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146005395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-16DOI: 10.1093/eurheartj/ehaf857
Bin He, Jun Li
{"title":"Challenges and improvements in the study of live zoster vaccination's impact on cardiovascular health.","authors":"Bin He, Jun Li","doi":"10.1093/eurheartj/ehaf857","DOIUrl":"10.1093/eurheartj/ehaf857","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":" ","pages":"381"},"PeriodicalIF":35.6,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145400081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-16DOI: 10.1093/eurheartj/ehaf797
Daniela Pedicino, Carlo Patrono
{"title":"Weekly Journal Scan: spironolactone does not ACHIEVE reduction of cardiovascular outcomes in dialysis patients.","authors":"Daniela Pedicino, Carlo Patrono","doi":"10.1093/eurheartj/ehaf797","DOIUrl":"10.1093/eurheartj/ehaf797","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":" ","pages":"385-386"},"PeriodicalIF":35.6,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145476745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-16DOI: 10.1093/eurheartj/ehaf1044
Johann Bauersachs, Shelley Zieroth, Rudolf A de Boer
{"title":"The year in cardiovascular medicine 2025: the top 10 papers in heart failure.","authors":"Johann Bauersachs, Shelley Zieroth, Rudolf A de Boer","doi":"10.1093/eurheartj/ehaf1044","DOIUrl":"https://doi.org/10.1093/eurheartj/ehaf1044","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":" ","pages":""},"PeriodicalIF":35.6,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145988798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-16DOI: 10.1093/eurheartj/ehaf805
Jose L Merino, James A Reiffel, A John Camm
{"title":"EHRA practical compendium of antiarrhythmic drugs: 10 key messages on contemporary use.","authors":"Jose L Merino, James A Reiffel, A John Camm","doi":"10.1093/eurheartj/ehaf805","DOIUrl":"10.1093/eurheartj/ehaf805","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":" ","pages":"286-289"},"PeriodicalIF":35.6,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145476596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-16DOI: 10.1093/eurheartj/ehaf653
Natalie Arnold, Wolfgang Koenig
{"title":"Quiet flames: inflammation without traditional risk factors.","authors":"Natalie Arnold, Wolfgang Koenig","doi":"10.1093/eurheartj/ehaf653","DOIUrl":"10.1093/eurheartj/ehaf653","url":null,"abstract":"","PeriodicalId":11976,"journal":{"name":"European Heart Journal","volume":" ","pages":"315-317"},"PeriodicalIF":35.6,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144947692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}