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Global burden of cardiovascular diseases: projections from 2025 to 2050.
IF 8.3 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-09-13 DOI: 10.1093/eurjpc/zwae281
Bryan Chong,Jayanth Jayabaskaran,Silingga Metta Jauhari,Siew Pang Chan,Rachel Goh,Martin Tze Wah Kueh,Henry Li,Yip Han Chin,Gwyneth Kong,Vickram Vijay Anand,Jiong-Wei Wang,Mark Muthiah,Vardhmaan Jain,Anurag Mehta,Shir Lynn Lim,Roger Foo,Gemma A Figtree,Stephen J Nicholls,Mamas A Mamas,James L Januzzi,Nicholas W S Chew,A Mark Richards,Mark Y Chan
AIMSThe prediction of future trends in cardiovascular disease (CVD) mortality and their risk factors can assist policy-makers in healthcare planning. This study aims to project geospatial trends in CVDs and their underlying risk factors from 2025 to 2050.METHODS AND RESULTSUsing historical data on mortality and disability-adjusted life years (DALYs) from the Global Burden of Disease (GBD) 2019 study, encompassing the period of 1990 to 2019, Poisson regression was performed to model mortality and DALYs associated with CVD and its associated risk factors from 2025 to 2050. Subgroup analysis was based on GBD super-regions. Between 2025 and 2050, a 90.0% increase in cardiovascular prevalence, 73.4% increase in crude mortality, and 54.7% increase in crude DALYs are projected, with an expected 35.6 million cardiovascular deaths in 2050 (from 20.5 million in 2025). However, age-standardized cardiovascular prevalence will be relatively constant (-3.6%), with decreasing age-standardized mortality (-30.5%) and age-standardized DALYs (-29.6%). In 2050, ischaemic heart disease will remain the leading cause of cardiovascular deaths (20 million deaths) while high systolic blood pressure will be the main cardiovascular risk factor driving mortality (18.9 million deaths). Central Europe, Eastern Europe, and Central Asia super-region is set to incur the highest age-standardized cardiovascular mortality rate in 2050 (305 deaths per 100 000 population).CONCLUSIONIn the coming decades, the relatively constant age-standardized prevalence of global CVD suggests that the net effect of summative preventative efforts will likely continue to be unchanged. The fall in age-standardized cardiovascular mortality reflects the improvement in medical care following diagnosis. However, future healthcare systems can expect a rapid rise in crude cardiovascular mortality, driven by the ageing global populace. The continued rise in CVD burden will largely be attributed to atherosclerotic diseases.REGISTRATIONNot applicable.
目的预测心血管疾病(CVD)死亡率及其风险因素的未来趋势有助于政策制定者进行医疗保健规划。本研究旨在预测 2025 年至 2050 年心血管疾病及其潜在风险因素的地理空间趋势。方法与结果利用《全球疾病负担》(GBD)2019 年研究(涵盖 1990 年至 2019 年)中有关死亡率和残疾调整寿命年数(DALYs)的历史数据,采用泊松回归法建立 2025 年至 2050 年与心血管疾病及其相关风险因素有关的死亡率和残疾调整寿命年数模型。分组分析基于 GBD 超级区域。预计 2025 年至 2050 年期间,心血管病发病率将增加 90.0%,粗死亡率将增加 73.4%,粗残疾调整寿命年数将增加 54.7%,预计 2050 年心血管病死亡人数将达到 3560 万(2025 年为 2050 万)。然而,年龄标准化心血管病发病率将相对稳定(-3.6%),年龄标准化死亡率(-30.5%)和年龄标准化残疾调整寿命年数(-29.6%)将下降。2050 年,缺血性心脏病仍将是心血管疾病死亡的主要原因(2000 万人死亡),而高收缩压将是导致死亡的主要心血管风险因素(1890 万人死亡)。2050 年,中欧、东欧和中亚超级区域将成为年龄标准化心血管死亡率最高的地区(每 10 万人中有 305 人死亡)。年龄标准化心血管病死亡率的下降反映了诊断后医疗护理的改善。然而,在全球人口老龄化的推动下,未来的医疗保健系统预计心血管疾病的粗死亡率将迅速上升。心血管疾病负担的持续上升将主要归因于动脉粥样硬化性疾病。
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引用次数: 0
EJPC @ a glance: focus issue on cardiovascular risk prediction in primary and secondary prevention. EJPC @ a glance:关于一级和二级预防中心血管风险预测的焦点问题。
IF 8.3 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-09-13 DOI: 10.1093/eurjpc/zwae283
Gal Tsaban,Victor Aboyans
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引用次数: 0
Effect of Behavior-change Interventions on Daily Physical Activity in Patients with Intermittent Claudication: The OPTIMA Systematic Review with Meta-Analysis. 行为改变干预对间歇性跛行患者日常体育锻炼的影响:OPTIMA 系统回顾与元分析》。
IF 8.3 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-09-12 DOI: 10.1093/eurjpc/zwae296
Ukachukwu O Abaraogu,Philippa Dall,Chris Seenan,Sarah Rhodes,Trish Gorely,Joanna McParland,Julie Brittenden,Ebuka M Anieto,Lorna Booth,Cathy Gormal,Jeremy Dearling,Candida Fenton,Sarah Audsley,Kimberley Fairer,Lindsay Bearne,Dawn A Skelton
AIMSThe study aimed to synthesize evidence of daily physical activity (PA) following Behavior-change technique (BCT)-based interventions compared to any control in individuals with peripheral arterial disease/intermittent claudication (PAD/IC); and examine the relationship between BCTs and daily PA.METHODSSystematic search of 11 databases from inception to 30/11/2022 was conducted, plus weekly email alerts of new literature until 31/8/2023. Studies comparing BCT-based interventions with any control were included. Primary analysis involved a pairwise random-effects meta-analysis. Risk of bias was assessed using the Cochrane-RoB-2 and ROBINS-I tools. Certainty of evidence was evaluated with the GRADE system. The Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guideline was followed. Outcome measures were short-term (<6 months) change in daily PA, and maintenance of the daily PA (6 months or longer) reported as standardized mean differences (SMDs) with 95% confidence intervals (95%CIs).RESULTSForty-one studies (4,339 patients; 26 RCTs/3,357 patients; 15 non-RCTs/982 patients; study mean age 60.3 to 73.8, 29.5% female) were included. Eleven RCTs (15 comparisons, 952 participants) suggested that BCT-based interventions increased daily PA in the short term compared to non-SET [increase of 0.20 SMD (95%CI: 0.07 to 0.33), ∼473 steps/day] with high certainty. Evidence of maintenance of daily PA (≥6 months) is unclear [increase of 0.12 SMD (95%CI: -0.04 to 0.29); ∼288 steps/day; 6RCTs, 8 comparisons, 899 participants], with moderate certainty. For daily PA, compared to SET it was inconclusive both for < 6months change [-0.13 SMD, 95%CI: -0.43 to 0.16); 3RCTs, 269 participants; low certainty] and ≥6months [-0.04 SMD, 95%CI: -0.55 to 0.47); 1 RCT, 89 participants; very low certainty]. It was unclear whether the number of BCTs or any BCT domain were independently related to an increase in PA.CONCLUSIONBCT-based interventions improve short-term daily PA in people with PAD/IC compared to non-SET controls. Evidence for maintenance of the improved PA at 6 months or longer and comparison with SET is uncertain. BCT-based interventions are effective choices for enhancing daily PA in PAD/IC.
目的本研究旨在综合外周动脉疾病/间歇性跛行(PAD/IC)患者在接受基于行为改变技术(BCT)的干预后,每日体育锻炼(PA)的证据,并研究BCT与每日体育锻炼之间的关系。方法对11个数据库进行了系统检索,检索时间从开始到2022年11月30日,另外每周通过电子邮件提醒新文献,直到2023年8月31日。纳入了比较基于 BCT 的干预措施和任何对照的研究。主要分析包括成对随机效应荟萃分析。使用 Cochrane-RoB-2 和 ROBINS-I 工具评估偏倚风险。证据的确定性采用 GRADE 系统进行评估。遵循《系统综述和荟萃分析首选报告项目》(PRISMA)指南。结果纳入了 41 项研究(4339 名患者;26 项 RCTs/3357 名患者;15 项非 RCTs/982 名患者;研究平均年龄为 60.3 岁至 73.8 岁,29.5% 为女性)。11项RCT(15项比较,952名参与者)表明,与非SET相比,基于BCT的干预在短期内增加了每日PA[增加0.20 SMD(95%CI:0.07至0.33),∼473步/天],其确定性很高。维持每日运动量(≥6 个月)的证据尚不明确[增加 0.12 SMD(95%CI:-0.04 至 0.29);∼288 步/天;6 项研究,8 项比较,899 名参与者],具有中等确定性。对于日常活动量,与 SET 相比,<6 个月的变化[-0.13 SMD,95%CI:-0.43 至 0.16;3 项研究,269 名参与者;低确定性]和≥6 个月的变化[-0.04 SMD,95%CI:-0.55 至 0.47;1 项研究,89 名参与者;极低确定性]均无定论。]结论与非SET对照组相比,基于BCT的干预能改善PAD/IC患者的短期日常活动量。6个月或更长时间后,PA改善的维持情况以及与SET的比较尚不确定。基于 BCT 的干预是提高 PAD/IC 患者日常 PA 的有效选择。
{"title":"Effect of Behavior-change Interventions on Daily Physical Activity in Patients with Intermittent Claudication: The OPTIMA Systematic Review with Meta-Analysis.","authors":"Ukachukwu O Abaraogu,Philippa Dall,Chris Seenan,Sarah Rhodes,Trish Gorely,Joanna McParland,Julie Brittenden,Ebuka M Anieto,Lorna Booth,Cathy Gormal,Jeremy Dearling,Candida Fenton,Sarah Audsley,Kimberley Fairer,Lindsay Bearne,Dawn A Skelton","doi":"10.1093/eurjpc/zwae296","DOIUrl":"https://doi.org/10.1093/eurjpc/zwae296","url":null,"abstract":"AIMSThe study aimed to synthesize evidence of daily physical activity (PA) following Behavior-change technique (BCT)-based interventions compared to any control in individuals with peripheral arterial disease/intermittent claudication (PAD/IC); and examine the relationship between BCTs and daily PA.METHODSSystematic search of 11 databases from inception to 30/11/2022 was conducted, plus weekly email alerts of new literature until 31/8/2023. Studies comparing BCT-based interventions with any control were included. Primary analysis involved a pairwise random-effects meta-analysis. Risk of bias was assessed using the Cochrane-RoB-2 and ROBINS-I tools. Certainty of evidence was evaluated with the GRADE system. The Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guideline was followed. Outcome measures were short-term (<6 months) change in daily PA, and maintenance of the daily PA (6 months or longer) reported as standardized mean differences (SMDs) with 95% confidence intervals (95%CIs).RESULTSForty-one studies (4,339 patients; 26 RCTs/3,357 patients; 15 non-RCTs/982 patients; study mean age 60.3 to 73.8, 29.5% female) were included. Eleven RCTs (15 comparisons, 952 participants) suggested that BCT-based interventions increased daily PA in the short term compared to non-SET [increase of 0.20 SMD (95%CI: 0.07 to 0.33), ∼473 steps/day] with high certainty. Evidence of maintenance of daily PA (≥6 months) is unclear [increase of 0.12 SMD (95%CI: -0.04 to 0.29); ∼288 steps/day; 6RCTs, 8 comparisons, 899 participants], with moderate certainty. For daily PA, compared to SET it was inconclusive both for < 6months change [-0.13 SMD, 95%CI: -0.43 to 0.16); 3RCTs, 269 participants; low certainty] and ≥6months [-0.04 SMD, 95%CI: -0.55 to 0.47); 1 RCT, 89 participants; very low certainty]. It was unclear whether the number of BCTs or any BCT domain were independently related to an increase in PA.CONCLUSIONBCT-based interventions improve short-term daily PA in people with PAD/IC compared to non-SET controls. Evidence for maintenance of the improved PA at 6 months or longer and comparison with SET is uncertain. BCT-based interventions are effective choices for enhancing daily PA in PAD/IC.","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":null,"pages":null},"PeriodicalIF":8.3,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142263758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cardiovascular risk estimation: can a risk prediction model derived in one country be used in another? 心血管风险评估:在一个国家得出的风险预测模型能在另一个国家使用吗?
IF 8.3 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-09-10 DOI: 10.1093/eurjpc/zwae286
Ian M Graham
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引用次数: 0
Electrocardiographic and morphological cardiac remodeling in competitive female athletes - a scoping review. 竞技女运动员的心电图和心脏形态重塑--范围综述。
IF 8.3 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-09-10 DOI: 10.1093/eurjpc/zwae293
Nicole M Panhuyzen-Goedkoop,Juliette C van Hattum,Florian E Beerman,André L M Verbeek,René J Goedkoop,Arjan Malekzadeh,Ron J G Peters,Harald T Jørstad
AIMSTo quantitatively analyse exercise-induced cardiac remodeling (EICR) data in female athletes.METHODSThis scoping review included from the databases Medline, Embase, and Google Scholar, peer-reviewed original English-language articles on female athlete-populations aged ≥18 years containing data on electrocardiography (ECG), echocardiography or cardiac magnetic resonance (CMR), and excluded athletes with cardiovascular conditions. From the extracted ECG data, we calculated prevalence percentages, and from the imaging data we compared the results with the upper reference limits of the general female population (URL).RESULTSWe included 31 articles comprising 4,896 female athletes, aged mean 22.2±4.6 years. On ECG (n=889), most prevalent findings were increased QRS voltages for LV hypertrophy (LVH, n=97), J-point elevation (JPE, n=108), and T-wave inversion (TWI, n=104). On echocardiography (n=4,644), we found increased mean of means BSA-indexed volumes for the LV 67.3 mL/m2 (95%CI 66.8-67.8; URL=61) and right ventricle (RV) 82.7 mL/m2 (95%CI 79.5-86.0; URL=74), while atrial volumes, septal wall thickness and LV mass were within the upper reference limits of the general population (URL). On CMR (n=309), the mean of means volumes of LA (62.0 mL/m2, 95%CI 58.8-65.2; URL=61), LV (103.4 mL/m2, 95%Ci 101.8-105.0; URL=96), and RV (105.3 mL/m2, 95%CI 103.3-110.6; URL=107.2) were >URL.CONCLUSIONFemale athletes demonstrate distinct features of electrical (increased QRS voltages for LVH, JPE and TWI) and morphological EICR (biventricular dilatation). On CMR, LA was borderline dilated. Extensive studies on female athletes are needed to understand sex specific EICR.
目的定量分析女运动员运动诱发的心脏重塑(EICR)数据。方法本范围性综述从 Medline、Embase 和 Google Scholar 等数据库中收录了经同行评审的关于年龄≥18 岁的女运动员群体的原创英文文章,这些文章包含心电图(ECG)、超声心动图或心脏磁共振(CMR)数据,并排除了患有心血管疾病的运动员。我们从提取的心电图数据中计算了患病率百分比,并从成像数据中将结果与一般女性人群的参考上限(URL)进行了比较。结果我们共收录了 31 篇文章,涉及 4896 名女运动员,平均年龄(22.2±4.6)岁。在心电图上(889人),最常见的发现是左心室肥厚(LVH,97人)、J点抬高(JPE,108人)和T波倒置(TWI,104人)的QRS电压增高。在超声心动图检查(n=4,644)中,我们发现左心室 67.3 mL/m2 (95%CI 66.8-67.8; URL=61)和右心室 82.7 mL/m2 (95%CI 79.5-86.0; URL=74)的平均 BSA 指数容积增大,而心房容积、室间隔壁厚度和左心室质量均在一般人群的参考上限(URL)范围内。在 CMR(n=309)中,LA(62.0 mL/m2,95%CI 58.8-65.2;URL=61)、LV(103.4 mL/m2,95%Ci 101.8-105.0;URL=96)和 RV(105.3 mL/m2,95%CI 103.3-110.6;URL=107.2)的平均体积均>URL.CONCL.COM。结论女性运动员表现出明显的电学特征(LVH、JPE和TWI的QRS电压增高)和形态学EICR特征(双心室扩张)。在CMR上,LA呈边缘扩张。需要对女运动员进行广泛研究,以了解特定性别的 EICR。
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引用次数: 0
Comparison of resting heart rate and left ventricular ejection fraction in elite endurance athletes and the general population. 精英耐力运动员与普通人群静息心率和左心室射血分数的比较。
IF 8.4 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-09-09 DOI: 10.1093/eurjpc/zwae294
Jon Magne Letnes, Bjarne Martens Nes, Øyvind Sandbakk, Arnt Erik Tjønna, Thomas Fremo, Christian Moldjord, Morten Høydal, Ulrik Wisløff, Håvard Dalen
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引用次数: 0
The role of exercise training on cardiovascular risk factors and heart disease in patients with chronic kidney disease G3-G5 and G5D: a Clinical Consensus Statement of the European Association of Preventive Cardiology of the ESC and the European Association of Rehabilitation in Chronic Kidney Disease. 运动训练对慢性肾脏病 G3-G5 和 G5D 患者心血管风险因素和心脏病的作用:ESC 欧洲预防心脏病学协会 (EAPC) 和欧洲慢性肾脏病康复协会 (EURORECKD) 临床共识声明。
IF 8.4 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-09-06 DOI: 10.1093/eurjpc/zwae130
Evangelia Kouidi, Henner Hanssen, Kirsten Anding-Rost, Adamasco Cupisti, Asterios Deligiannis, Clemens Grupp, Pelagia Koufaki, Paul Leeson, Eva Segura-Orti, Amaryllis Van Craenenbroeck, Emeline Van Craenenbroeck, Naomi Clyne, Martin Halle

Cardiovascular (CV) morbidity and mortality is high in patients with chronic kidney disease (CKD). Most patients reveal a high prevalence of CV risk factors such as diabetes or arterial hypertension and many have manifest cardiovascular disease (CVD), such as coronary artery disease and chronic heart failure with an increased risk of clinical events including sudden cardiac death. Diabetes mellitus and hypertension contribute to the development of CKD and the prevalence of CKD is in the range of 20-65% in diabetic and 30-50% in hypertensive patients. Therefore, prevention and optimal treatment of CV risk factors and comorbidities are key strategies to reduce CV risk and improve survival in CKD. Beyond common CV risk factors, patients with CKD are often physically inactive and have low physical function leading to subsequent frailty with muscle fatigue and weakness, sarcopenia and increased risk of falling. Consequently, the economic health burden of CKD is high, requiring feasible strategies to counteract this vicious cycle. Regular physical activity and exercise training (ET) have been shown to be effective in improving risk factors, reducing CVD and reducing frailty and falls. Nonetheless, combining ET and a healthy lifestyle with pharmacological treatment is not frequently applied in clinical practice. For that reason, this Clinical Consensus Statement reviews the current literature and provides evidence-based data regarding the role of ET in reducing CV and overall burden in patients with CKD. The aim is to increase awareness among cardiologists, nephrologists, and healthcare professionals of the potential of exercise therapy in order to encourage implementation of ET in clinical practice, eventually reducing CV risk and disease, as well as reducing frailty in patients with CKD G3-G5D.

慢性肾脏病(CKD)患者的心血管疾病(CV)发病率和死亡率很高。大多数患者都存在糖尿病或动脉高血压等心血管疾病危险因素,许多患者还伴有明显的心血管疾病(CVD),如冠状动脉疾病和慢性心力衰竭,从而增加了包括心脏性猝死在内的临床事件的风险。糖尿病和高血压会导致慢性肾脏病的发生,而慢性肾脏病的发病率在糖尿病患者中为 20%-65%,在高血压患者中为 30%-50%。因此,预防和优化治疗心血管疾病风险因素和合并症是降低心血管疾病风险和提高 CKD 患者生存率的关键策略。除了常见的心血管疾病风险因素外,慢性肾脏病患者通常缺乏运动,身体功能低下,从而导致肌肉疲劳和无力、肌肉疏松症和跌倒风险增加。因此,慢性肾脏病对健康造成的经济负担很高,需要采取可行的策略来应对这一恶性循环。有研究表明,有规律的体育锻炼和运动训练能有效改善风险因素,降低心血管疾病的发病率,减少虚弱和跌倒。然而,在临床实践中,将运动训练和健康生活方式与药物治疗相结合的做法并不常见。因此,本临床共识声明回顾了目前的文献,并提供了有关运动训练在减轻慢性肾脏病患者心血管疾病和整体负担方面作用的循证数据。其目的是提高心脏病专家、肾病专家和医护人员对运动疗法潜力的认识,从而鼓励在临床实践中实施运动训练,最终降低 CV 风险和疾病,并减轻 CKD G3 至 G5D 患者的虚弱程度。
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引用次数: 0
Superior effect of long-term community-based high-intensity interval training on cardiovascular and functional parameters in low-income older women. 基于社区的长期高强度间歇训练对低收入老年妇女心血管和功能参数的卓越影响。
IF 8.4 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-09-06 DOI: 10.1093/eurjpc/zwae200
Vanessa Teixeira do Amaral, Gabriel de Souza Zanini, Isabela Roque Marçal, Lucas Bueno Gimenez, Bianca Fernandes, Emmanuel Gomes Ciolac
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引用次数: 0
The many faces of exercise intensity: a call to agree on definitions and provide standardized prescriptions. 运动强度的多面性:呼吁就定义达成一致并提供标准化处方。
IF 8.4 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-09-06 DOI: 10.1093/eurjpc/zwae034
Sara Faggian, Anna Centanini, Giulia Quinto, Marco Vecchiato, Andrea Ermolao, Francesca Battista, Daniel Neunhaeuserer
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引用次数: 0
High-load resistance training in cardiac rehabilitation: is it time to debunk old clinical dogmas for a better clinical tomorrow? 心脏康复中的高负荷阻力训练:是时候破除陈旧的临床教条,创造更美好的临床明天了吗?
IF 8.4 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-09-06 DOI: 10.1093/eurjpc/zwae079
Tim Kambič, Dominique Hansen, Thijs M H Eijsvogels
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引用次数: 0
期刊
European journal of preventive cardiology
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