Pub Date : 2025-12-01Epub Date: 2025-02-07DOI: 10.1080/20008066.2025.2456381
Pia Maria Schwegler, Katharina Gossmann, Theresa Neumann, Anne Moser, Theresa Speth, Rita Rosner
Background: Previous research suggests that psychotherapists' readiness to treat traumatized patients varies according to patient and therapist characteristics, including the patient's refugee background.Objective: This study aims to examine the relationship between psychotherapists' readiness to treat patients with symptoms of post-traumatic stress disorder and various patient and therapist characteristics, including refugee background and country of origin.Method: In our vignette study with a nationwide online survey in Germany (N = 871), we assessed the readiness of licensed psychotherapists (LPTs) and therapists in training (PiTs) to treat patients with PTSD. Vignettes described patients with PTSD who differed in gender, refugee background, and country of origin (Syria vs. Ukraine). Participants rated treatment readiness and expected treatment success based on the vignette they received.Results: Treatment readiness and expected success were significantly lower for refugee patients. There was no difference in treatment readiness between refugees from Syria and Ukraine, but therapists expected less therapeutic success for Syrian patients compared to Ukrainian patients. Gender did not influence the results.Conclusions: The study shows that refugee background and country of origin influence psychotherapists' readiness to treat PTSD and their expectations of treatment success. These findings highlight potential reasons for the undertreatment of refugees and suggest opportunities for intervention and training, such as informing therapists about effective treatments for refugee patients.
{"title":"Psychotherapists' readiness to treat PTSD: the influence of refugees' country of origin.","authors":"Pia Maria Schwegler, Katharina Gossmann, Theresa Neumann, Anne Moser, Theresa Speth, Rita Rosner","doi":"10.1080/20008066.2025.2456381","DOIUrl":"10.1080/20008066.2025.2456381","url":null,"abstract":"<p><p><b>Background</b><i>:</i> Previous research suggests that psychotherapists' readiness to treat traumatized patients varies according to patient and therapist characteristics, including the patient's refugee background.<b>Objective</b>: This study aims to examine the relationship between psychotherapists' readiness to treat patients with symptoms of post-traumatic stress disorder and various patient and therapist characteristics, including refugee background and country of origin.<b>Method</b>: In our vignette study with a nationwide online survey in Germany (<i>N</i> = 871), we assessed the readiness of licensed psychotherapists (LPTs) and therapists in training (PiTs) to treat patients with PTSD. Vignettes described patients with PTSD who differed in gender, refugee background, and country of origin (Syria vs. Ukraine). Participants rated treatment readiness and expected treatment success based on the vignette they received.<b>Results</b>: Treatment readiness and expected success were significantly lower for refugee patients. There was no difference in treatment readiness between refugees from Syria and Ukraine, but therapists expected less therapeutic success for Syrian patients compared to Ukrainian patients. Gender did not influence the results.<b>Conclusions</b><i>:</i> The study shows that refugee background and country of origin influence psychotherapists' readiness to treat PTSD and their expectations of treatment success. These findings highlight potential reasons for the undertreatment of refugees and suggest opportunities for intervention and training, such as informing therapists about effective treatments for refugee patients.</p>","PeriodicalId":12055,"journal":{"name":"European Journal of Psychotraumatology","volume":"16 1","pages":"2456381"},"PeriodicalIF":4.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11809162/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143363839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2025-01-03DOI: 10.1080/20008066.2024.2444745
Karen-Inge Karstoft, Erik Vindbjerg, Anni B S Nielsen, Søren Bo Andersen, Sofie Folke
Background: A number of studies have tested the factor structure of the suggested ICD-11 symptom criteria for PTSD and complex PTSD (CPTSD) across various trauma populations, finding support for two different models in line with the ICD-11 theoretical rationale.Objective: Here, we aim to explore the factor structure of the Danish version of the International Trauma Questionnaire (ITQ) by testing two alternative factor models that have previously gained support in a large sample of treatment-seeking veterans.Method: Treatment-seeking Danish soldiers and veterans (N = 599) recruited from the Military Psychology Department in the Danish Defence completed the International Trauma Questionnaire (ITQ). Confirmatory factor analysis (CFA) was used to assess fit of a first-order and a second-order model.Results: Both models fit the data well but displayed latent variable correlations above 1 and negative variances (known as Heywood cases), indicating model misspecification or other problems. The specification problems included the latent variable Affect Dysregulation.Conclusions: Based on our results and results reported in previous CFAs of the ITQ, we suggest consideration of the proposed models. While many previous studies did find support for the models with no indications of misfit, others find Heywood cases concerning the same items and latent variables as our analysis. Hence, models of (C)PTSD based on the ITQ should be carefully evaluated and interpreted.
{"title":"The factor structure of the International Trauma Questionnaire - Heywood cases in confirmatory factor analysis.","authors":"Karen-Inge Karstoft, Erik Vindbjerg, Anni B S Nielsen, Søren Bo Andersen, Sofie Folke","doi":"10.1080/20008066.2024.2444745","DOIUrl":"https://doi.org/10.1080/20008066.2024.2444745","url":null,"abstract":"<p><p><b>Background:</b> A number of studies have tested the factor structure of the suggested ICD-11 symptom criteria for PTSD and complex PTSD (CPTSD) across various trauma populations, finding support for two different models in line with the ICD-11 theoretical rationale.<b>Objective:</b> Here, we aim to explore the factor structure of the Danish version of the International Trauma Questionnaire (ITQ) by testing two alternative factor models that have previously gained support in a large sample of treatment-seeking veterans.<b>Method:</b> Treatment-seeking Danish soldiers and veterans (<i>N</i> = 599) recruited from the Military Psychology Department in the Danish Defence completed the International Trauma Questionnaire (ITQ). Confirmatory factor analysis (CFA) was used to assess fit of a first-order and a second-order model.<b>Results:</b> Both models fit the data well but displayed latent variable correlations above 1 and negative variances (known as Heywood cases), indicating model misspecification or other problems. The specification problems included the latent variable Affect Dysregulation.<b>Conclusions:</b> Based on our results and results reported in previous CFAs of the ITQ, we suggest consideration of the proposed models. While many previous studies did find support for the models with no indications of misfit, others find Heywood cases concerning the same items and latent variables as our analysis. Hence, models of (C)PTSD based on the ITQ should be carefully evaluated and interpreted.</p>","PeriodicalId":12055,"journal":{"name":"European Journal of Psychotraumatology","volume":"16 1","pages":"2444745"},"PeriodicalIF":4.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142920806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: This study aims to elucidate the causal relationship between childhood maltreatment (CM) and subsequent mental health outcomes, including major depressive disorder (MDD), anxiety (ANX), post-traumatic stress disorder (PTSD), suicide attempts, and non-fatal self-harm. Utilising Mendelian Randomisation (MR) and genome-wide association studies (GWAS) data from individuals of European descent, this research applies a rigorous analytical methodology to large-scale datasets, overcoming the confounding variables inherent in previous observational studies.Methods: Genetic data were obtained from publicly available GWAS on individuals of European ancestry, focusing on Childhood Maltreatment (CM), Major Depressive Disorder (MDD), Anxiety (ANX), Post-Traumatic Stress Disorder (PTSD), Age at First Episode of Depression, Number of Depression Episodes, Non-fatal self-harm, and Suicide Attempts. Mendelian Randomisation (MR) analyses were conducted to investigate the causal impact of CM on these outcomes. Sensitivity analyses included IVW, MR Egger, WM, and MR-PRESSO. FDR corrections were applied to account for multiple testing. Results were presented as odds ratios (ORs) with confidence intervals (CIs).Results: Significant associations were identified between CM and the likelihood of developing MDD (IVW: OR = 2.28, 95% CI = 1.66-3.14, PFDR < .001), ANX (IVW: OR = 1.01, 95% CI = 1.00-1.02, PFDR =.032), and PTSD (IVW: OR = 2.29, 95% CI = 1.43-3.67, PFDR =.001). CM was also linked to increased non-fatal self-harm (IVW: OR = 1.06, 95% CI = 1.04-1.08, PFDR <.001), higher frequency of depressive episodes (IVW: β=0.31, 95% CI = 0.17-0.46, PFDR <.001), and earlier onset of depression (IVW: β=-0.17, 95% CI = -0.32 to - 0.02, PFDR =.033). No significant association was found between CM and suicide attempts (IVW: OR = 1.09, 95% CI = 0.81-1.45, PFDR =.573).Conclusion: This study provides robust evidence that CM is a significant causal factor for MDD, ANX, PTSD, and non-fatal self-harming behaviours. It is associated with a higher frequency of depressive episodes and earlier onset of depression. These findings highlight the need for early intervention and targeted prevention strategies to address the long-lasting psychological impacts of CM.
背景:本研究旨在阐明儿童虐待与心理健康结局的因果关系,包括重度抑郁障碍(MDD)、焦虑(ANX)、创伤后应激障碍(PTSD)、自杀企图和非致命性自残。利用孟德尔随机化(MR)和全基因组关联研究(GWAS)数据,本研究对大规模数据集应用了严格的分析方法,克服了以往观察性研究中固有的混杂变量。方法:从公开的GWAS中获得欧洲血统个体的遗传数据,重点关注儿童虐待(CM)、重度抑郁症(MDD)、焦虑(ANX)、创伤后应激障碍(PTSD)、首次抑郁发作年龄、抑郁发作次数、非致命性自残和自杀企图。进行孟德尔随机化(MR)分析以调查CM对这些结果的因果影响。敏感性分析包括IVW、MR Egger、WM和MR- presso。采用FDR修正来解释多重检验。结果以比值比(ORs)和置信区间(CIs)表示。结果:CM与发生重度抑郁症(IVW: OR = 2.28, 95% CI = 1.66-3.14, PFDR OR = 1.01, 95% CI = 1.00-1.02, PFDR = 0.032)和PTSD (IVW: OR = 2.29, 95% CI = 1.43-3.67, PFDR = 0.001)的可能性存在显著相关性。CM也与非致命性自我伤害增加有关(IVW: OR = 1.06, 95% CI = 1.04-1.08, PFDR β=0.31, 95% CI = 0.17-0.46, PFDR β=-0.17, 95% CI =- 0.32至- 0.02,PFDR = 0.033)。CM与自杀企图之间无显著关联(IVW: OR = 1.09, 95% CI = 0.81-1.45, PFDR =.573)。结论:本研究提供了强有力的证据,证明CM是MDD、ANX、PTSD和非致命性自残行为的重要诱因。它与更高频率的抑郁发作和更早的抑郁发作有关。这些发现强调了早期干预和有针对性的预防策略的必要性,以解决CM的长期心理影响。
{"title":"Childhood maltreatment and mental health: causal links to depression, anxiety, non-fatal self-harm, suicide attempts, and PTSD.","authors":"Zheng Zhang, Chenggang Jiang, Xinglian Wang, Haitang Qiu, Jiazheng Li, Yating Wang, Qinghua Luo, Yuanzhi Ju","doi":"10.1080/20008066.2025.2480884","DOIUrl":"10.1080/20008066.2025.2480884","url":null,"abstract":"<p><p><b>Background:</b> This study aims to elucidate the causal relationship between childhood maltreatment (CM) and subsequent mental health outcomes, including major depressive disorder (MDD), anxiety (ANX), post-traumatic stress disorder (PTSD), suicide attempts, and non-fatal self-harm. Utilising Mendelian Randomisation (MR) and genome-wide association studies (GWAS) data from individuals of European descent, this research applies a rigorous analytical methodology to large-scale datasets, overcoming the confounding variables inherent in previous observational studies.<b>Methods:</b> Genetic data were obtained from publicly available GWAS on individuals of European ancestry, focusing on Childhood Maltreatment (CM), Major Depressive Disorder (MDD), Anxiety (ANX), Post-Traumatic Stress Disorder (PTSD), Age at First Episode of Depression, Number of Depression Episodes, Non-fatal self-harm, and Suicide Attempts. Mendelian Randomisation (MR) analyses were conducted to investigate the causal impact of CM on these outcomes. Sensitivity analyses included IVW, MR Egger, WM, and MR-PRESSO. FDR corrections were applied to account for multiple testing. Results were presented as odds ratios (ORs) with confidence intervals (CIs).<b>Results:</b> Significant associations were identified between CM and the likelihood of developing MDD (IVW: <i>OR</i> = 2.28, 95% <i>CI </i>= 1.66-3.14, <i>P</i><sub>FDR </sub>< .001), ANX (IVW: <i>OR</i> = 1.01, 95% <i>CI </i>= 1.00-1.02, <i>P</i><sub>FDR</sub> =.032), and PTSD (IVW: <i>OR</i> = 2.29, 95% <i>CI </i>= 1.43-3.67, <i>P</i><sub>FDR</sub> =.001). CM was also linked to increased non-fatal self-harm (IVW: <i>OR</i> = 1.06, 95% <i>CI </i>= 1.04-1.08, <i>P</i><sub>FDR</sub> <.001), higher frequency of depressive episodes (IVW: <i>β</i>=0.31, 95% <i>CI </i>= 0.17-0.46, <i>P</i><sub>FDR</sub> <.001), and earlier onset of depression (IVW: <i>β</i>=-0.17, 95% <i>CI </i>= -0.32 to - 0.02, <i>P</i><sub>FDR</sub> =.033). No significant association was found between CM and suicide attempts (IVW: <i>OR</i> = 1.09, 95% <i>CI </i>= 0.81-1.45, <i>P</i><sub>FDR</sub> =.573).<b>Conclusion:</b> This study provides robust evidence that CM is a significant causal factor for MDD, ANX, PTSD, and non-fatal self-harming behaviours. It is associated with a higher frequency of depressive episodes and earlier onset of depression. These findings highlight the need for early intervention and targeted prevention strategies to address the long-lasting psychological impacts of CM.</p>","PeriodicalId":12055,"journal":{"name":"European Journal of Psychotraumatology","volume":"16 1","pages":"2480884"},"PeriodicalIF":4.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12082731/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2025-08-04DOI: 10.1080/20008066.2025.2534310
Angela J Zaur, Dongho Shin, Jasmine Lewis, Robert A Perera, William C Walker, Amma Agyemang, Tara Austin, Cooper Hodges, Sarah L Martindale, Mary Jo Pugh, Ananda B Amstadter, Christina M Sheerin
Background: Individuals with pre-existing heavy alcohol use, prior traumatic exposures, and psychiatric disorders were considered an at-risk group for increased alcohol use and problems in the context of the COVID-19 pandemic.Objective: This study recruited from a multi-centre longitudinal cohort study of US military service members/veterans with combat exposure to examine the trajectories of alcohol use and problems in the context of a prolonged stressor.Methods: Individuals who endorsed heavy drinking and completed a measure of PTSD symptoms prior to the pandemic were invited to participate in a longitudinal survey study at three time points, three months apart, during the second year of the pandemic. Participants (N = 44) completed surveys assessing alcohol consumption and alcohol-related problems (via the AUDIT), PTSD symptoms (via the PCL-5), and infection mitigation behaviours (via a COVID-19 specific survey). Random intercept models were fitted to the longitudinal data for each of these outcomes, covarying for demographics, pandemic quarantine/physical distancing experience, pre-pandemic baseline alcohol consumption and PTSD symptoms, and time-varying alcohol consumption and alcohol-related problems as well as PTSD symptoms.Results: We did not find an increase in alcohol consumption or problems over time. However, pre-pandemic alcohol consumption predicted alcohol consumption over time (B = 0.52, SE = 0.11, p < .01). Time-varying alcohol consumption and PTSD symptoms predicted alcohol problems over time (B = 0.84, SE = 0.18, p < .01; B = 0.04, SE = 0.02, p < .05, respectively).Conclusions: Findings highlight the relevance of pre-existing hazardous alcohol consumption prior to stressors as well as ongoing consumption and PTSD symptoms as risk factors for alcohol-related problems. Findings captured more chronic impacts of pandemic stressors and demonstrated that heavy drinking and PTSD are notable risk factors for alcohol-related problems even if in the context of stabilizing, albeit still high, alcohol use.
背景:在COVID-19大流行背景下,先前存在大量酒精使用、创伤性暴露和精神疾病的个体被认为是酒精使用增加和出现问题的高危群体。目的:本研究从一项多中心纵向队列研究中招募了有战斗暴露的美国军人/退伍军人,以检查长期压力源背景下酒精使用的轨迹和问题。方法:在大流行前支持大量饮酒并完成PTSD症状测量的个体被邀请在大流行第二年的三个时间点(间隔三个月)参加一项纵向调查研究。参与者(N = 44)完成了评估饮酒和酒精相关问题(通过审计)、创伤后应激障碍症状(通过PCL-5)和感染缓解行为(通过COVID-19特定调查)的调查。对每一项结果的纵向数据进行随机截距模型拟合,对人口统计学、大流行隔离/物理距离经历、大流行前基线饮酒和PTSD症状、时变饮酒和酒精相关问题以及PTSD症状进行共变。结果:我们没有发现随着时间的推移饮酒增加或出现问题。然而,流行病前的酒精消费预测了一段时间内的酒精消费(B = 0.52, SE = 0.11, p B = 0.84, SE = 0.18, p B = 0.04, SE = 0.02, p)。结论:研究结果强调了在压力源之前存在的危险酒精消费以及持续消费和PTSD症状作为酒精相关问题的危险因素的相关性。研究结果揭示了流行病压力源的更多慢性影响,并表明大量饮酒和创伤后应激障碍是酒精相关问题的显著风险因素,即使在酒精使用量稳定(尽管仍然很高)的情况下也是如此。
{"title":"Longitudinal predictors of alcohol use and problems during the COVID-19 pandemic in an at-risk veteran sample.","authors":"Angela J Zaur, Dongho Shin, Jasmine Lewis, Robert A Perera, William C Walker, Amma Agyemang, Tara Austin, Cooper Hodges, Sarah L Martindale, Mary Jo Pugh, Ananda B Amstadter, Christina M Sheerin","doi":"10.1080/20008066.2025.2534310","DOIUrl":"10.1080/20008066.2025.2534310","url":null,"abstract":"<p><p><b>Background:</b> Individuals with pre-existing heavy alcohol use, prior traumatic exposures, and psychiatric disorders were considered an at-risk group for increased alcohol use and problems in the context of the COVID-19 pandemic.<b>Objective:</b> This study recruited from a multi-centre longitudinal cohort study of US military service members/veterans with combat exposure to examine the trajectories of alcohol use and problems in the context of a prolonged stressor.<b>Methods:</b> Individuals who endorsed heavy drinking and completed a measure of PTSD symptoms prior to the pandemic were invited to participate in a longitudinal survey study at three time points, three months apart, during the second year of the pandemic. Participants (<i>N</i> = 44) completed surveys assessing alcohol consumption and alcohol-related problems (via the AUDIT), PTSD symptoms (via the PCL-5), and infection mitigation behaviours (via a COVID-19 specific survey). Random intercept models were fitted to the longitudinal data for each of these outcomes, covarying for demographics, pandemic quarantine/physical distancing experience, pre-pandemic baseline alcohol consumption and PTSD symptoms, and time-varying alcohol consumption and alcohol-related problems as well as PTSD symptoms.<b>Results:</b> We did not find an increase in alcohol consumption or problems over time. However, pre-pandemic alcohol consumption predicted alcohol consumption over time (<i>B</i> = 0.52, SE = 0.11, <i>p</i> < .01). Time-varying alcohol consumption and PTSD symptoms predicted alcohol problems over time (<i>B</i> = 0.84, SE = 0.18, <i>p</i> < .01; <i>B</i> = 0.04, SE = 0.02, <i>p</i> < .05, respectively).<b>Conclusions:</b> Findings highlight the relevance of pre-existing hazardous alcohol consumption prior to stressors as well as ongoing consumption and PTSD symptoms as risk factors for alcohol-related problems. Findings captured more chronic impacts of pandemic stressors and demonstrated that heavy drinking and PTSD are notable risk factors for alcohol-related problems even if in the context of stabilizing, albeit still high, alcohol use.</p>","PeriodicalId":12055,"journal":{"name":"European Journal of Psychotraumatology","volume":"16 1","pages":"2534310"},"PeriodicalIF":4.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12322980/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144774900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2025-02-12DOI: 10.1080/20008066.2025.2463187
Shannon E Cusack, Anna W Wright, Peter B Barr, Emily Notari, Kaitlin E Bountress, Ananda B Amstadter
Objective: Posttraumatic stress disorder (PTSD) and life satisfaction phenotypes are inversely related on a phenotypic level. Given these established relations, researchers have begun to examine possible shared genetic contributions to these outcomes, though the existing genetic literature is sparse and examines these relations via univariate methods. We sought to examine the genetic architecture of PTSD and six life satisfaction and well-being phenotypes (i.e. subjective well-being, friend satisfaction, life satisfaction, family satisfaction, work satisfaction, and financial satisfaction) using a multivariate approach.Method: We used Genomic Structural Equation Modeling (gSEM) to analyze summary-level genetic data from large-scale GWAS of the European Ancestry.Results: Findings show that a two, correlated factors model fit the data best, in which PTSD and life satisfaction phenotypes load on separate but correlated factors.Conclusions: Findings suggest that, using multivariate methods, a latent factor capturing many different positive phenotypes is genetically related to PTSD. This finding confirms and extends prior phenotypic work demonstrating that PTSD and positive phenotypes are inversely related.
{"title":"Using genomic structural equation modeling to examine the genetic architecture of PTSD and life satisfaction phenotypes.","authors":"Shannon E Cusack, Anna W Wright, Peter B Barr, Emily Notari, Kaitlin E Bountress, Ananda B Amstadter","doi":"10.1080/20008066.2025.2463187","DOIUrl":"10.1080/20008066.2025.2463187","url":null,"abstract":"<p><p><b>Objective:</b> Posttraumatic stress disorder (PTSD) and life satisfaction phenotypes are inversely related on a phenotypic level. Given these established relations, researchers have begun to examine possible shared genetic contributions to these outcomes, though the existing genetic literature is sparse and examines these relations via univariate methods. We sought to examine the genetic architecture of PTSD and six life satisfaction and well-being phenotypes (i.e. subjective well-being, friend satisfaction, life satisfaction, family satisfaction, work satisfaction, and financial satisfaction) using a multivariate approach.<b>Method:</b> We used Genomic Structural Equation Modeling (gSEM) to analyze summary-level genetic data from large-scale GWAS of the European Ancestry.<b>Results:</b> Findings show that a two, correlated factors model fit the data best, in which PTSD and life satisfaction phenotypes load on separate but correlated factors.<b>Conclusions:</b> Findings suggest that, using multivariate methods, a latent factor capturing many different positive phenotypes is genetically related to PTSD. This finding confirms and extends prior phenotypic work demonstrating that PTSD and positive phenotypes are inversely related.</p>","PeriodicalId":12055,"journal":{"name":"European Journal of Psychotraumatology","volume":"16 1","pages":"2463187"},"PeriodicalIF":4.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11823395/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143398677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2025-10-15DOI: 10.1080/20008066.2025.2565060
Kristen Bermingham, Christopher Latourrette, Karen G Chartier, Ananda B Amstadter, Kaitlin Bountress
Background: Anxiety Sensitivity (AS), the belief that anxiety experiences have negative implications, is a prospective predictor of posttraumatic stress disorder (PTSD) and has been linked to changes in PTSD in experimental studies. AS is comprised of three sub-components: cognitive, physical, and social concerns. PTSD is moderately heritable and parental PTSD may increase risk for these AS facets both directly and through environmental influences like reduced social support.Objective: The present study will examine whether Parent PTSD is associated with reduced social support and in turn facets of AS.Method: Participants were recruited from an ongoing longitudinal study of college student mental health; 94 individuals with current alcohol use disorder (AUD), PTSD, both, or neither (i.e. trauma-exposed controls) were included.Results: Cross-sectional analyses revealed that offspring of parents with PTSD reported less social support in their families of origin, which was associated with higher AS-cognitive concerns. There was a direct effect of parent PTSD on physical concerns, but no effects of parent PTSD or support on social concerns.Conclusions: Offspring of parents with PTSD who perceive less family support may be at higher risk for internalising problems via increased negativity, and may not feel that their caregivers are reliable sources of emotional regulation. Therefore, reduced support may explain the path between parent PTSD and cognitive AS concerns. In contrast, it is possible that simply having a parent with PTSD who perhaps displays outward symptoms of anxiety increases risk for more AS physical concerns. Together, these findings suggest that offspring of parents with PTSD are a high-risk group on whom family-based interventions bolstering social support and AS (cognitive)-based interventions ought to be focused.
{"title":"Parent PTSD, social support and differential associations with facets of anxiety sensitivity.","authors":"Kristen Bermingham, Christopher Latourrette, Karen G Chartier, Ananda B Amstadter, Kaitlin Bountress","doi":"10.1080/20008066.2025.2565060","DOIUrl":"10.1080/20008066.2025.2565060","url":null,"abstract":"<p><p><b>Background:</b> Anxiety Sensitivity (AS), the belief that anxiety experiences have negative implications, is a prospective predictor of posttraumatic stress disorder (PTSD) and has been linked to changes in PTSD in experimental studies. AS is comprised of three sub-components: cognitive, physical, and social concerns. PTSD is moderately heritable and parental PTSD may increase risk for these AS facets both directly and through environmental influences like reduced social support.<b>Objective:</b> The present study will examine whether Parent PTSD is associated with reduced social support and in turn facets of AS.<b>Method:</b> Participants were recruited from an ongoing longitudinal study of college student mental health; 94 individuals with current alcohol use disorder (AUD), PTSD, both, or neither (i.e. trauma-exposed controls) were included.<b>Results:</b> Cross-sectional analyses revealed that offspring of parents with PTSD reported less social support in their families of origin, which was associated with higher AS-cognitive concerns. There was a direct effect of parent PTSD on physical concerns, but no effects of parent PTSD or support on social concerns.<b>Conclusions:</b> Offspring of parents with PTSD who perceive less family support may be at higher risk for internalising problems via increased negativity, and may not feel that their caregivers are reliable sources of emotional regulation. Therefore, reduced support may explain the path between parent PTSD and cognitive AS concerns. In contrast, it is possible that simply having a parent with PTSD who perhaps displays outward symptoms of anxiety increases risk for more AS physical concerns. Together, these findings suggest that offspring of parents with PTSD are a high-risk group on whom family-based interventions bolstering social support and AS (cognitive)-based interventions ought to be focused.</p>","PeriodicalId":12055,"journal":{"name":"European Journal of Psychotraumatology","volume":"16 1","pages":"2565060"},"PeriodicalIF":4.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12529740/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145291513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2025-07-18DOI: 10.1080/20008066.2025.2526885
Justina Pociūnaitė-Ott, Lonneke I M Lenferink
Introduction: The majority of grief research has assessed Prolonged Grief (PG) symptoms using cross-sectional surveys, which are limited in capturing within-person changes in daily grief reactions. These dynamic PG reactions can be more effectively assessed using Experience Sampling Methodology (ESM). Accordingly, this data note presents a Findable, Accessible, Interoperable, and Reusable (FAIR) archive comprising three existing ESM projects investigating PG reactions in daily life.Methods: Participants in this archive completed three data collection phases: baseline measures (including sociodemographic and loss characteristics, and psychopathology measures), a 14-day ESM phase (rating PG reactions and contextual factors up to five times daily), and follow-up psychopathology assessments. The participants provided explicit digital consent for the use and reuse of their data in scientific research.Results: In total, 315 people are included in this archive, with a total of 22,050 ESM-measurement points. The majority of the participants were middle-aged, identified as women, and had completed higher education. Almost half of the sample (48.73%) experienced the loss of a partner or child, the majority of these losses were due to natural causes (70.06%), and happened less than a year ago (59.24%). The data are stored in a trusted repository.Discussion: This archive demonstrates that it is feasible to develop a FAIR archive including existing data on PG reactions in daily life. Given the resource-intensive nature and richness of these data, we encourage researchers to reuse and/or share ESM-data through this archive, helping to deepen our understanding of grief in natural settings.
{"title":"A FAIR intensive longitudinal data archive on prolonged grief in daily life.","authors":"Justina Pociūnaitė-Ott, Lonneke I M Lenferink","doi":"10.1080/20008066.2025.2526885","DOIUrl":"10.1080/20008066.2025.2526885","url":null,"abstract":"<p><p><b>Introduction:</b> The majority of grief research has assessed Prolonged Grief (PG) symptoms using cross-sectional surveys, which are limited in capturing within-person changes in daily grief reactions. These dynamic PG reactions can be more effectively assessed using Experience Sampling Methodology (ESM). Accordingly, this data note presents a Findable, Accessible, Interoperable, and Reusable (FAIR) archive comprising three existing ESM projects investigating PG reactions in daily life.<b>Methods:</b> Participants in this archive completed three data collection phases: baseline measures (including sociodemographic and loss characteristics, and psychopathology measures), a 14-day ESM phase (rating PG reactions and contextual factors up to five times daily), and follow-up psychopathology assessments. The participants provided explicit digital consent for the use and reuse of their data in scientific research.<b>Results:</b> In total, 315 people are included in this archive, with a total of 22,050 ESM-measurement points. The majority of the participants were middle-aged, identified as women, and had completed higher education. Almost half of the sample (48.73%) experienced the loss of a partner or child, the majority of these losses were due to natural causes (70.06%), and happened less than a year ago (59.24%). The data are stored in a trusted repository.<b>Discussion:</b> This archive demonstrates that it is feasible to develop a FAIR archive including existing data on PG reactions in daily life. Given the resource-intensive nature and richness of these data, we encourage researchers to reuse and/or share ESM-data through this archive, helping to deepen our understanding of grief in natural settings.</p>","PeriodicalId":12055,"journal":{"name":"European Journal of Psychotraumatology","volume":"16 1","pages":"2526885"},"PeriodicalIF":4.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12278458/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144658793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2025-07-18DOI: 10.1080/20008066.2025.2523638
Belinda Graham, Anke Ehlers
Background: Bullying can be associated with emotional and social difficulties, but not all individuals experience enduring negative effects.Objective: This study aimed to explore beliefs about bullying, self, and other people among young adults who were bullied that may be associated with ongoing anxiety and distress related to those experiences.Method: Semi-structured interviews with 20 people, aged 18-29 years, who had experienced bullying were analysed using thematic analysis. The sample was split, by current symptoms of social anxiety and post-traumatic stress related to bullying, into a lower symptoms group (n = 12) and a higher symptoms group (n = 8).Results: Participants reported multiple types of bullying, including online. Four superordinate themes were identified in negative beliefs related to bullying experiences: personal deficiency (i.e. victimization was due to own low value or undesirable traits), social threat (i.e. wariness of others due to their negative motives or traits), acceptance is fragile (i.e. being accepted by others is transient and requires effort), and minimizing (i.e. downplaying severity and impact of past experiences). These were evident in both groups but were more frequently endorsed in the higher symptoms group.Conclusion: Negative appraisals related to bullying can persist into young adulthood and may influence social interactions and mental health. Interventions targeting these beliefs could mitigate negative outcomes and bolster resilience among individuals affected by bullying. Further research should explore these themes to inform effective therapeutic strategies for young adults who have been bullied.
{"title":"A qualitative analysis of young adults' beliefs about bullying: exploring associations with social anxiety and post-traumatic stress.","authors":"Belinda Graham, Anke Ehlers","doi":"10.1080/20008066.2025.2523638","DOIUrl":"10.1080/20008066.2025.2523638","url":null,"abstract":"<p><p><b>Background:</b> Bullying can be associated with emotional and social difficulties, but not all individuals experience enduring negative effects.<b>Objective:</b> This study aimed to explore beliefs about bullying, self, and other people among young adults who were bullied that may be associated with ongoing anxiety and distress related to those experiences.<b>Method:</b> Semi-structured interviews with 20 people, aged 18-29 years, who had experienced bullying were analysed using thematic analysis. The sample was split, by current symptoms of social anxiety and post-traumatic stress related to bullying, into a lower symptoms group (<i>n</i> = 12) and a higher symptoms group (<i>n</i> = 8).<b>Results:</b> Participants reported multiple types of bullying, including online. Four superordinate themes were identified in negative beliefs related to bullying experiences: personal deficiency (i.e. victimization was due to own low value or undesirable traits), social threat (i.e. wariness of others due to their negative motives or traits), acceptance is fragile (i.e. being accepted by others is transient and requires effort), and minimizing (i.e. downplaying severity and impact of past experiences). These were evident in both groups but were more frequently endorsed in the higher symptoms group.<b>Conclusion:</b> Negative appraisals related to bullying can persist into young adulthood and may influence social interactions and mental health. Interventions targeting these beliefs could mitigate negative outcomes and bolster resilience among individuals affected by bullying. Further research should explore these themes to inform effective therapeutic strategies for young adults who have been bullied.</p>","PeriodicalId":12055,"journal":{"name":"European Journal of Psychotraumatology","volume":"16 1","pages":"2523638"},"PeriodicalIF":4.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12278457/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144658794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2025-08-04DOI: 10.1080/20008066.2025.2532273
Oswald D Kothgassner, Sarah Macura, Andreas Goreis, Diana Klinger, Bettina Pfeffer, Sofia M Oehlke, Karin Prillinger, Johanna X Kafka, Heidi Elisabeth Zesch, Anna Felnhofer, Paul L Plener
Background: Psychophysiological dysregulations and negative alterations in cognitions and mood characterize post traumatic stress disorder (PTSD) and complex PTSD (C-PTSD), contributing to an increased risk of disorder persistence and chronic health problems. However, understanding the differences in physiological stress reactivity and negative cognitive-emotional patterns between adolescents with PTSD and C-PTSD remains a notable research gap.Objective: This study examined group differences in autonomic nervous system (ANS) reactivity during the sharing of a short trauma narrative, including resting and recovery phases, and compared subjective experiences of stress, shame, and guilt among adolescents with PTSD, C-PTSD, and trauma-exposed controls.Methods: In a repeated-measures design, 52 adolescents (14-18 years) with PTSD (n = 17), C-PTSD (n = 18), and a control group (n = 17) were assessed for heart rate, heart rate variability, and subjective experiences of stress, shame, and guilt during a standardized trauma interview, as well as during baseline and recovery phases.Results: Linear mixed-effects models revealed a significant interaction between group and time point (F = 4.134, p < .001). The C-PTSD group exhibited a significantly higher heart rate in the recovery phase compared to the PTSD (p = .010) and control groups (p = .036), alongside significantly higher subjective stress, guilt, and shame experiences. Main effects of group were identified for perceived stress (F = 7.543, p = .002), guilt (F = 21.779, p < .001), and shame (F = 19.309, p < .001), with the C-PTSD group exhibiting higher levels compared to PTSD and control groups across all conditions.Conclusions: Prolonged stress responses and elevated experiences of shame and guilt in adolescents with C-PTSD align with the diagnostic criteria of affective dysregulation and negative self-concept. Objective stress measures during trauma interviews may support the diagnosis of C-PTSD. Findings highlight the importance of phase-based trauma therapies that target emotional dysregulation, shame, and guilt.
{"title":"Stress reactivity during short trauma narratives in adolescents with post-traumatic stress disorder (PTSD) and complex PTSD.","authors":"Oswald D Kothgassner, Sarah Macura, Andreas Goreis, Diana Klinger, Bettina Pfeffer, Sofia M Oehlke, Karin Prillinger, Johanna X Kafka, Heidi Elisabeth Zesch, Anna Felnhofer, Paul L Plener","doi":"10.1080/20008066.2025.2532273","DOIUrl":"10.1080/20008066.2025.2532273","url":null,"abstract":"<p><p><b>Background:</b> Psychophysiological dysregulations and negative alterations in cognitions and mood characterize post traumatic stress disorder (PTSD) and complex PTSD (C-PTSD), contributing to an increased risk of disorder persistence and chronic health problems. However, understanding the differences in physiological stress reactivity and negative cognitive-emotional patterns between adolescents with PTSD and C-PTSD remains a notable research gap.<b>Objective:</b> This study examined group differences in autonomic nervous system (ANS) reactivity during the sharing of a short trauma narrative, including resting and recovery phases, and compared subjective experiences of stress, shame, and guilt among adolescents with PTSD, C-PTSD, and trauma-exposed controls.<b>Methods:</b> In a repeated-measures design, 52 adolescents (14-18 years) with PTSD (<i>n</i> = 17), C-PTSD (<i>n</i> = 18), and a control group (<i>n</i> = 17) were assessed for heart rate, heart rate variability, and subjective experiences of stress, shame, and guilt during a standardized trauma interview, as well as during baseline and recovery phases.<b>Results:</b> Linear mixed-effects models revealed a significant interaction between group and time point (<i>F</i> = 4.134, <i>p</i> < .001). The C-PTSD group exhibited a significantly higher heart rate in the recovery phase compared to the PTSD (<i>p</i> = .010) and control groups (<i>p</i> = .036), alongside significantly higher subjective stress, guilt, and shame experiences. Main effects of group were identified for perceived stress (<i>F</i> = 7.543, <i>p</i> = .002), guilt (<i>F</i> = 21.779, <i>p</i> < .001), and shame (<i>F</i> = 19.309, <i>p</i> < .001), with the C-PTSD group exhibiting higher levels compared to PTSD and control groups across all conditions.<b>Conclusions:</b> Prolonged stress responses and elevated experiences of shame and guilt in adolescents with C-PTSD align with the diagnostic criteria of affective dysregulation and negative self-concept. Objective stress measures during trauma interviews may support the diagnosis of C-PTSD. Findings highlight the importance of phase-based trauma therapies that target emotional dysregulation, shame, and guilt.</p>","PeriodicalId":12055,"journal":{"name":"European Journal of Psychotraumatology","volume":"16 1","pages":"2532273"},"PeriodicalIF":4.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12322999/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144774901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2025-06-06DOI: 10.1080/20008066.2025.2508548
Natalia E Fares-Otero, Silvia Amoretti, Brisa Solé, Sarah L Halligan, Eduard Vieta, Stefan Leucht, Soraya Seedat, Mathias Harrer
Background: Several psychosocial interventions have shown promising effects in treating people affected by childhood maltreatment (CM); however, their comparative efficacy on social functioning remains largely unknown. To address this issue, a systematic review and network meta-analysis (NMA) will be conducted to investigate the comparative efficacy of different psychosocial interventions on global social functioning and specific domains of social functioning, including behavioural, emotional, cognitive and physiological processes. We aim to develop a hierarchical ranking of existing psychosocial interventions concerning their efficacy and acceptability which could inform treatment guidelines.Methods: Randomised controlled trials (RCTs) investigating psychosocial interventions for individuals with exposure to CM when they were younger than age 18 will be included. Primary outcomes will be global and domains of social functioning (measured up to 3, 6, 12 months and at the longest follow-up). Study drop-out will be a secondary outcome that will serve as a measure of acceptability. Study selection and data extraction will be performed by at least two independent reviewers. We will assess the risk of bias for each study using the Cochrane Risk of Bias tool 2 (RoB2) and evaluate the confidence in the results using Confidence in Network Meta-Analysis (CINeMA). The effects of potential moderators, such as age (children/adolescents vs. adults), population type (clinical vs. non-clinical samples), or sex (% males), socioeconomic status (low-income vs. middle-high-income countries), and intervention characteristics (individual vs. group training, number of sessions) will be analysed using subgroup-analyses or meta-regressions. Other candidate moderators/mediators (personality, post-traumatic symptoms, brain structure/function, cognitive reserve) will also be explored and narratively summarised. Sensitivity analyses will be conducted to explore further heterogeneity and assess the robustness of our findings.Discussion: This systematic review and NMA aims to compare multiple existing psychosocial interventions in individuals affected by CM and establish the relative rankings of these interventions for social functioning. Our results may provide practical guidance concerning the most effective psychosocial interventions to reduce the societal burden associated with CM.Protocol registration: PROSPERO CRD42022347034.
{"title":"Efficacy of psychosocial interventions on social functioning in individuals with childhood maltreatment experiences: a protocol for a systematic review and network meta-analysis.","authors":"Natalia E Fares-Otero, Silvia Amoretti, Brisa Solé, Sarah L Halligan, Eduard Vieta, Stefan Leucht, Soraya Seedat, Mathias Harrer","doi":"10.1080/20008066.2025.2508548","DOIUrl":"10.1080/20008066.2025.2508548","url":null,"abstract":"<p><p><b>Background:</b> Several psychosocial interventions have shown promising effects in treating people affected by childhood maltreatment (CM); however, their comparative efficacy on social functioning remains largely unknown. To address this issue, a systematic review and network meta-analysis (NMA) will be conducted to investigate the comparative efficacy of different psychosocial interventions on global social functioning and specific domains of social functioning, including behavioural, emotional, cognitive and physiological processes. We aim to develop a hierarchical ranking of existing psychosocial interventions concerning their efficacy and acceptability which could inform treatment guidelines.<b>Methods:</b> Randomised controlled trials (RCTs) investigating psychosocial interventions for individuals with exposure to CM when they were younger than age 18 will be included. Primary outcomes will be global and domains of social functioning (measured up to 3, 6, 12 months and at the longest follow-up). Study drop-out will be a secondary outcome that will serve as a measure of acceptability. Study selection and data extraction will be performed by at least two independent reviewers. We will assess the risk of bias for each study using the Cochrane Risk of Bias tool 2 (RoB2) and evaluate the confidence in the results using Confidence in Network Meta-Analysis (CINeMA). The effects of potential moderators, such as age (children/adolescents <i>vs.</i> adults), population type (clinical <i>vs.</i> non-clinical samples), or sex (% males), socioeconomic status (low-income <i>vs.</i> middle-high-income countries), and intervention characteristics (individual <i>vs.</i> group training, number of sessions) will be analysed using subgroup-analyses or meta-regressions. Other candidate moderators/mediators (personality, post-traumatic symptoms, brain structure/function, cognitive reserve) will also be explored and narratively summarised. Sensitivity analyses will be conducted to explore further heterogeneity and assess the robustness of our findings.<b>Discussion:</b> This systematic review and NMA aims to compare multiple existing psychosocial interventions in individuals affected by CM and establish the relative rankings of these interventions for social functioning. Our results may provide practical guidance concerning the most effective psychosocial interventions to reduce the societal burden associated with CM.<b>Protocol registration:</b> PROSPERO CRD42022347034.</p>","PeriodicalId":12055,"journal":{"name":"European Journal of Psychotraumatology","volume":"16 1","pages":"2508548"},"PeriodicalIF":4.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12147484/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144233593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}