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Resilience frameworks, measurement tools, and transmission processes in the context of man-made collective trauma: a meta-synthesis and multilevel meta-analysis. 人为集体创伤背景下的复原力框架、测量工具和传播过程:一项综合和多层次元分析。
IF 4.1 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-11-19 DOI: 10.1080/20008066.2025.2582455
Japhet Niyonsenga, Stefan Jansen, Eugene Rutembesa, Erno Hermans, Nadia Monacelli, Luca Caricati

Background: Populations affected by war, genocide, political violence, and forced displacement endure severe psychosocial disruption. Resilience is increasingly recognized as key to recovery, yet its definitions, measurement, and mechanisms of transmission in collective trauma contexts remain inconsistently addressed.Objective: This review aimed to synthesize how resilience is conceptualized, measured, and transmitted in the context of collective trauma, and to quantitatively assess the association between trauma exposure and resilience.Methods: Following PRISMA 2020 guidelines and registered in PROSPERO (CRD420250651118), we searched seven databases (e.g. Scopus, Embase, PubMed, PsycINFO) and screened 16,447 records. Eligible studies examined both man-made collective trauma exposure and resilience as an outcome or process. After full-text review, 53 studies were included: 16 qualitative studies and 9 reviews underwent thematic synthesis and 28 were included in a three-level random-effects meta-analysis of 43 effect sizes. Moderator analyses explored demographic and conceptual influences on the association.Results: Three integrative models of resilience were identified: (1) intrapersonal resource models (e.g. coping, emotional regulation), (2) multisystemic and relational process models (e.g. family, community support), and (3) sociocultural continuity and identity models (e.g. collective memory, tradition). These were derived from seven definitions categories, seven domains of protective and risk factors, and five measurement categories. The meta-analysis showed a significant negative association between trauma exposure and resilience (r = -0.109, 95%CI [-0.163, -0.055], p < .0001; I² = 82.3%), robust after outlier adjustment (r = -0.121). Stronger associations were observed in predominantly male samples (r = -0.176) and in intrapersonal or national resilience frameworks (r = -0.136), compared to relational models (r = -0.038), and across age in a quadratic pattern (QM[2] = 11.21, p = .0037). Trauma type, timing, and measurement method were not significant moderators.Conclusion: Resilience following collective trauma is best conceptualized as a multidimensional, context-sensitive process involving psychological, social, and cultural dimensions. Findings support an integrative framework and call for culturally grounded and system-oriented interventions.

背景:受战争、种族灭绝、政治暴力和被迫流离失所影响的人口遭受严重的心理社会破坏。人们越来越认识到复原力是恢复的关键,但在集体创伤背景下,复原力的定义、测量和传播机制仍未得到一致的解决。目的:本综述旨在综合在集体创伤背景下,心理弹性是如何被概念化、测量和传递的,并定量评估创伤暴露与心理弹性的关系。方法:按照PRISMA 2020指南并在PROSPERO注册(CRD420250651118),检索Scopus、Embase、PubMed、PsycINFO等7个数据库,筛选16,447条记录。合格的研究将人为的集体创伤暴露和复原力作为结果或过程进行了检查。全文审查后,纳入53项研究:16项定性研究和9项综述进行专题综合,28项纳入43个效应大小的三水平随机效应荟萃分析。调节分析探讨了人口统计和概念对协会的影响。结果:发现了三种心理弹性的整合模型:(1)个人资源模型(如应对、情绪调节);(2)多系统和关系过程模型(如家庭、社区支持);(3)社会文化连续性和身份模型(如集体记忆、传统)。这些数据来源于七个定义类别,七个保护和风险因素领域,以及五个测量类别。meta分析显示创伤暴露与心理恢复之间存在显著负相关(r = -0.109, 95%CI [-0.163, -0.055], p²= 82.3%),在离群值调整后呈显著负相关(r = -0.121)。与相关模型(r = -0.038)相比,在以男性为主的样本中(r = -0.176)和在个人或国家弹性框架中(r = -0.136)观察到更强的关联,并且在年龄上呈二次型模式(QM[2] = 11.21, p = 0.0037)。创伤类型、时间和测量方法均无显著调节作用。结论:集体创伤后的复原力是一个涉及心理、社会和文化维度的多维、情境敏感的过程。调查结果支持一个综合框架,并呼吁采取基于文化和面向系统的干预措施。
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引用次数: 0
The relation between post-migration stressors and trauma treatment outcomes: a scoping review. 迁移后应激源与创伤治疗结果之间的关系:范围综述。
IF 4.1 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-10-28 DOI: 10.1080/20008066.2025.2570929
Alva Mässing, Etzel Cardeña

Background: People seeking refuge and asylum must often endure diverse adversities before, during, and after migration, making them more susceptible to develop psychological problems. The effect of post-migration stressors on responsiveness to psychological treatment is unclear.Objectives: To: (1) evaluate the scope of the literature on the relation between post-migration stressors (e.g. struggles related to legal status in the context of resettlement) and outcomes of interventions targeting PTSD and comorbid conditions, in adult refugees and asylum seekers; (2) identify conceptual and methodological limitations of the literature; and (3) present limitations and recommendations for future research.Methods: This review follows the guidelines of PRISMA-ScR for Scoping Reviews, and the Population, Concept, and Context (PCC) framework for identifying concepts pertaining to the review question and the search strategy.Results: From 1,151 studies found through PsycINFO, PubMed, Web of Science Select, and review of sources, we assessed the 14 studies that fulfilled our criteria and found various post-migration barriers and facilitators of treatment success. Obtaining a more secure immigration status, reported in four studies, was the most emphasized factor associated with clinical improvement. Although the quality of the studies was overall high, there were frequent study limitations including small sample sizes and inconsistent post-stressor measures.Conclusion: Recommendations for future research include more robust methodologies, including mixed and longitudinal designs, and consistently using valid tools to assess post-migration stressors. The studies provide evidence for the effectiveness of psychological treatment in reducing symptoms of distress, despite being implemented in the context of post-migration stress. Post-migration stressors, although they may hamper treatment results, are not an indication to withhold treatment but a sign that additional services may be needed, but uniform and consistent evaluation of post-migration stressors should be implemented.

背景:寻求庇护和庇护的人在移民之前、期间和之后往往必须忍受各种各样的逆境,使他们更容易产生心理问题。迁移后应激源对心理治疗反应的影响尚不清楚。(1)评估关于移民后压力源(例如在重新安置背景下与法律地位相关的斗争)与针对成年难民和寻求庇护者的创伤后应激障碍和合并症的干预结果之间关系的文献范围;(2)识别文献在概念和方法上的局限性;(3)提出了未来研究的局限性和建议。方法:本综述遵循PRISMA-ScR范围综述的指南,以及人群、概念和背景(PCC)框架来识别与综述问题和搜索策略相关的概念。结果:从PsycINFO、PubMed、Web of Science Select和文献综述中发现的1151项研究中,我们评估了14项符合我们标准的研究,并发现了各种迁移后障碍和治疗成功的促进因素。在四项研究中,获得更安全的移民身份是与临床改善相关的最重要因素。尽管这些研究的总体质量很高,但经常存在研究局限性,包括样本量小和应激后测量不一致。结论:对未来研究的建议包括更稳健的方法,包括混合和纵向设计,并始终使用有效的工具来评估迁移后的压力源。这些研究为心理治疗在减轻痛苦症状方面的有效性提供了证据,尽管是在移民后压力的背景下实施的。移徙后的压力因素虽然可能妨碍治疗效果,但不是停止治疗的迹象,而是可能需要额外服务的迹象,但应对移徙后的压力因素进行统一和一致的评估。
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引用次数: 0
Empowering narratives: aid to self-help for Ukrainian refugees: a randomized controlled trial of Narrative Exposure Therapy (NET) delivered by supervised Ukrainian health workers in Norway. 授权叙述:援助乌克兰难民自助:在挪威由受监督的乌克兰卫生工作者提供的叙述暴露疗法(NET)的随机对照试验。
IF 4.1 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-10-27 DOI: 10.1080/20008066.2025.2567094
Vanessa Nolasco Ferreira, Helene Hjelmervik, Ashley Rebecca Bell-Mizori, Miroslava Tokovska, Signe Alexandra Domogalla, Fernanda Serpeloni, Susanne Axelson, Ivan Arango, Sarah Weber

Background: The Russian invasion of Ukraine has resulted in forced displacement, with over six million Ukrainian refugees across Europe, of whom 81,770 are residing in Norway. This displacement and, in many cases, preceding war experiences, has led to increased vulnerability to trauma and mental health challenges. There is to date little knowledge about the extent to which structured mental health interventions can mitigate symptoms in Ukrainian refugees. Narrative Exposure Therapy (NET), a short-term trauma-focused intervention, has demonstrated efficacy in reducing post-traumatic stress disorder (PTSD), depression and dissociation symptoms among individuals exposed to organized violence and war.Aim: The protocol aims to assess the clinical effects of NET on PTSD, dissociation, and depression symptoms among Ukrainian refugees in Norway and to facilitate training and supervised praxis for Ukrainian health professionals in using NET.Methods: This study employs a pretest-posttest randomized controlled experimental design (RCT). Ukrainian health workers in Norway will receive a total of 450 hours of NET training through an online course. As a part of the training, they will, under supervision, administrate NET to Ukrainian refugees. Participants will be screened and assessed at three time points: baseline, immediately after treatment, and at a 6-month follow-up. Validated instruments in Ukrainian and Russian will be used to assess trauma experiences, symptoms, and comorbidities. Exclusion criteria: active psychotic spectrum disorders, neurodevelopmental disorders and concurrent trauma therapy. The study also contains an embedded qualitative sub study that will involve phronetic iterative thematic analysis of anonymized therapy narratives collected during NET sessions, aiming to understand how participants construct meaning from traumatic events, how narrative coherence evolves throughout therapy, and how identity reconstruction occurs post-trauma.Trial registration: ClinicalTrials.gov identifier: NCT07062042..

背景:俄罗斯入侵乌克兰导致被迫流离失所,欧洲各地有600多万乌克兰难民,其中81,770人居住在挪威。这种流离失所以及在许多情况下战前的经历,使他们更容易受到创伤和心理健康方面的挑战。迄今为止,人们对有组织的心理健康干预措施能在多大程度上减轻乌克兰难民的症状知之甚少。叙述暴露疗法(NET)是一种以创伤为重点的短期干预措施,在暴露于有组织暴力和战争的个体中,已证明对减少创伤后应激障碍(PTSD)、抑郁和分离症状有效。目的:该议定书旨在评估NET对在挪威的乌克兰难民的创伤后应激障碍、分离和抑郁症状的临床影响,并促进乌克兰卫生专业人员在使用NET方面的培训和监督实践。方法:采用前测后测随机对照实验设计(RCT)。在挪威的乌克兰卫生工作人员将通过在线课程接受总计450小时的NET培训。作为培训的一部分,他们将在监督下管理乌克兰难民的信息技术。参与者将在三个时间点进行筛选和评估:基线,治疗后立即和6个月的随访。经过验证的乌克兰和俄罗斯仪器将用于评估创伤经历、症状和合并症。排除标准:活动性精神病谱系障碍、神经发育障碍和并发创伤治疗。本研究还包含一项嵌入的定性子研究,该研究将涉及在NET会话期间收集的匿名治疗叙事的phronetic迭代主题分析,旨在了解参与者如何从创伤事件中构建意义,叙事一致性如何在整个治疗过程中演变,以及创伤后身份重建如何发生。试验注册:ClinicalTrials.gov标识符:NCT07062042。
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引用次数: 0
Correction. 修正。
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-03-25 DOI: 10.1080/20008066.2025.2476823
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引用次数: 0
The role of prenatal stress and maternal trauma responses in predicting children's mental health during war. 产前压力和母体创伤反应在预测战争期间儿童心理健康方面的作用。
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-02-28 DOI: 10.1080/20008066.2025.2468542
Karen Yirmiya, Amit Klein, Shir Atzil, Noa Yakirevich-Amir, Rena Bina, Inbal Reuveni

Background: The negative effects of prenatal stress on children's development and the buffering effects of maternal behaviour are well documented. However, specific maternal responses to trauma, particularly among families experiencing cumulative stressors during pregnancy and early childhood, remain less understood.Objective: This study investigated the interplay between prenatal stress in the context of the coronavirus disease 2019 (COVID-19) pandemic and consequent maternal trauma responses and children's difficulties in the context of war-related trauma.Methods: We recruited 318 pregnant women in Israel during the first wave of the COVID-19 pandemic (Time 1). Prenatal depression, anxiety, and COVID-related stress symptoms were assessed. When children were approximately 3.5 years old (SD = 0.02), the mothers were asked to report on parental responses related to the ongoing war and their child's emotional and behavioural difficulties (Time 2). Structural equation modelling was used to examine how maternal trauma responses mediate the association between prenatal stress-related mental health symptoms and children's difficulties during war.Results: Maternal prenatal depressive, anxious, and COVID-19-related stress symptoms predicted maladaptive maternal trauma responses during the war, which in turn were associated with increased emotional and behavioural problems in their children. Among the specific maternal trauma-related responses examined, cognitive avoidance and overprotectiveness were the only behavioural responses during the war significantly associated with children's difficulties.Conclusions: Our study highlights the impact of pandemic-related prenatal stress on maternal responses and children's difficulties during war, emphasizing the importance of identifying at-risk families as well as developing targeted interventions that mitigate negative parenting responses, particularly avoidance and overprotection.

背景:产前压力对儿童发育的负面影响和母亲行为的缓冲作用是有案可查的。然而,产妇对创伤的具体反应,特别是在怀孕和幼儿期经历累积压力的家庭中,仍然知之甚少。目的:研究2019冠状病毒病(COVID-19)大流行背景下的产前应激与随之而来的母亲创伤反应和战争相关创伤背景下的儿童困难之间的相互作用。方法:在第一波COVID-19大流行(时间1)期间,我们在以色列招募了318名孕妇。评估产前抑郁、焦虑和与covid相关的压力症状。当孩子大约3.5岁(SD = 0.02)时,母亲被要求报告与持续战争相关的父母反应及其孩子的情绪和行为困难(时间2)。结构方程模型用于研究母亲创伤反应如何介导产前压力相关心理健康症状与儿童战争期间困难之间的关联。结果:母亲产前抑郁、焦虑和与covid -19相关的压力症状预示着战争期间母亲的创伤反应不良,而这反过来又与孩子的情绪和行为问题增加有关。在所检查的与母亲创伤有关的具体反应中,认知回避和过度保护是战争期间唯一与儿童困难显著相关的行为反应。结论:我们的研究强调了与大流行病有关的产前压力对母亲反应和战争期间儿童困难的影响,强调了识别有风险家庭以及制定有针对性的干预措施以减轻消极的养育反应,特别是回避和过度保护的重要性。
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引用次数: 0
Dissociative experiences in individuals with subclinical psychosis and a history of developmental trauma: a qualitative study. 亚临床精神病和发展性创伤史患者的解离经历:一项定性研究。
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-03-11 DOI: 10.1080/20008066.2025.2472473
Eirini Aikaterini Melegkovits, Ava Mason, Jordan Reid, Hind Akooly, Paul Jung, Michael Bloomfield

Background: Among individuals with psychotic experiences, those with a history of developmental trauma face greater symptom severity and worse clinical outcomes compared to those without. Dissociation constitutes a prominent, characteristic of this group's clinical presentation, whose nuances and associated characteristics remain however understudied in psychosis research. We aimed to address this gap by conducting a qualitative study to investigate the phenomenology, context, and impact of dissociative experiences in individuals with subclinical psychosis and a history of developmental trauma.Methods: 25 UK-based participants with a history of developmental trauma and meeting criteria for subclinical psychosis, based on the CAPE-15, were recruited via social media. Participants attended semi-structured interviews online, which were transcribed verbatim and analysed with thematic analysis by two researchers.Results: Thematic analysis yielded the following themes: (1) Phenomenology of Dissociation; (2) Context of Dissociation; (3) Impact of Dissociation; (4) Dissociation and Psychotic-like Phenomena. Participants described experiences of detachment and compartmentalisation, which when experienced were confusing and often distressing. Dissociation was linked to affective experiences, their history of developmental trauma and psychotic-like experiences.Conclusion: This study elucidates the complex and varied nature of dissociative experiences in individuals with subclinical psychosis with a history of developmental trauma. These findings highlight the need for further research to understand the manifestation of dissociation in this population and the links with distress and other aspects of psychopathology. Importantly, it is essential to use this understanding to inform the development of interventions and improve clinical recognition and management.

背景:在有精神病经历的个体中,那些有发展性创伤史的人比那些没有发展性创伤史的人面临更严重的症状和更差的临床结果。分离构成了这一群体临床表现的一个突出特征,其细微差别和相关特征在精神病研究中仍未得到充分研究。为了解决这一问题,我们进行了一项定性研究,调查亚临床精神病患者和有发展性创伤史的个体的解离经历的现象学、背景和影响。方法:根据CAPE-15,通过社交媒体招募了25名有发展性创伤史并符合亚临床精神病标准的英国参与者。参与者参加了半结构化的在线访谈,访谈内容由两位研究人员逐字记录并进行专题分析。结果:主题分析产生了以下主题:(1)解离现象学;(2)游离语境;(3)解离的影响;(4)分离和精神类现象。参与者描述了脱离和隔离的经历,当经历这些经历时,他们会感到困惑和痛苦。分离与情感经历、发育创伤史和类似精神病的经历有关。结论:本研究阐明了有发展性创伤史的亚临床精神病患者分离体验的复杂性和多样性。这些发现强调了进一步研究的必要性,以了解这一人群中分离的表现,以及与痛苦和精神病理学其他方面的联系。重要的是,利用这一认识来告知干预措施的发展和改善临床认识和管理是必不可少的。
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引用次数: 0
Psychometric accuracy of the Dutch Child and Adolescent Trauma Screener. 荷兰儿童和青少年创伤筛查的心理测量准确性。
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-01-21 DOI: 10.1080/20008066.2025.2450985
Lieke H Kooij, Irma M Hein, Cedric Sachser, Samantha Bouwmeester, Madelief Bosse, Ramón J L Lindauer

Objective: The aim of this study is to investigate the psychometrics of the Dutch version of the Child and Adolescent Trauma Screener (CATS-2). By this, an international recognized instrument to screen symptoms of post-traumatic stress (PTSS) in children and adolescents according to the Diagnostic and Statistical Manual for Mental Disorders, 5th edition (DSM-5) becomes available for Dutch youth.Procedure and Method: Based on the validated CATS-2 we established the Dutch version, named the KJTS. A total of 587 children and adolescent, age 7-21, and 658 caregivers referred to mental health care services in Amsterdam was included in the study to examine psychometric properties. The construct was tested by confirmatory factor analysis (CFA). Furthermore reliability, convergent-divergent patterns and diagnostic test accuracy were examined.Results: The underlying DSM-5 factor structure with four symptom clusters (re-experiencing, avoidance, negative alterations in mood and cognitions, hyperarousal) was supported by CFA showing a good fit for the selfreport (CFI = .95, TLI = .94), and an acceptable fit for the caregiver report (CFI = .90, TLI = .89). The KJTS showed excellent reliability (alpha = .92) on both selfreport and caregiver report. The convergent-discriminant validity pattern showed medium to strong correlations with measures of internalization problems, such as anxiety and affective problems (r = .44-.72) and low to medium correlations with externalizing symptoms (r = .21-.36). The ROC-curve analysis has proven a good accuracy (AUC = .81; n = 106).Discussion and conclusion: This study demonstrates the psychometric accuracy of the KJTS in a Dutch clinical population. The KJTS reflects adequately the dimensionality of PTSD as described in the DSM-5, with a good fit for selfreports, an acceptable fit for caregiver reports, excellent reliability and sufficient validity. Limitations are described. The outcomes support the use of the KJTS in research and clinical practice for screening and monitoring of PTSS.

目的:探讨荷兰版儿童与青少年创伤筛查量表(CATS-2)的心理测量学特征。据此,根据《精神障碍诊断和统计手册》第5版(DSM-5),荷兰青年可获得一项国际公认的工具,用于筛查儿童和青少年的创伤后应激症状。程序和方法:在经过验证的cat -2的基础上建立了荷兰语版本,命名为KJTS。在阿姆斯特丹,共有587名7-21岁的儿童和青少年,以及658名心理健康护理服务人员被纳入研究,以检查心理测量特性。采用验证性因子分析(CFA)对结构进行检验。此外,可靠性,收敛-发散模式和诊断测试的准确性进行了检验。结果:基础的DSM-5因子结构具有四个症状群(再体验、回避、情绪和认知的负性改变、亢奋),CFA支持其与自我报告(CFI =)吻合良好。95, TLI = .94),可接受的适合照顾者报告(CFI = .94)。90, tli = .89)。KJTS在自我报告和照顾者报告上均表现出极好的信度(alpha = 0.92)。收敛-判别效度模式显示与内化问题(如焦虑和情感问题)的测量具有中等到强的相关性(r = 0.44 - 0.72),与外化症状的测量具有低到中等的相关性(r = 0.21 - 0.36)。roc曲线分析具有良好的准确度(AUC = .81;n = 106)。讨论和结论:这项研究证明了荷兰临床人群中KJTS的心理测量准确性。KJTS充分反映了DSM-5中所描述的PTSD的维度,与自我报告的契合度很好,与护理者报告的契合度也可以接受,具有出色的信度和足够的效度。描述了局限性。结果支持在研究和临床实践中使用KJTS筛查和监测PTSS。
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引用次数: 0
Treating sleep disturbances in refugees and asylum seekers: results from a randomized controlled pilot trial evaluating the STARS group intervention. 治疗难民和寻求庇护者的睡眠障碍:一项评估STARS组干预的随机对照试验结果。
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-02-10 DOI: 10.1080/20008066.2025.2455248
Britta Dumser, Celina L Müller, Thomas Ehring, Gabriela G Werner, Theresa Koch

Background: Sleep disturbances are highly prevalent in traumatized refugees and often persist despite treatment, and adapted scalable interventions are needed. The group intervention 'Sleep Training adapted for Refugees' (STARS) is a culturally- and context-sensitive approach based on evidence-based treatments for sleep disturbances (e.g. CBT-I, IRT). This study evaluated the feasibility, acceptability, and effectiveness of STARS.Method: A randomized-controlled trial (STARS vs. waitlist) with 47 young male Afghan refugees was conducted in a routine clinical setting (DRKS-ID: DRKS00024419) with pre-, post- and 3-month follow-up assessments. The primary outcome was insomnia severity (Insomnia Severity Index); secondary outcomes included PTSD, anxiety and depression symptoms, nightmares, coping with nightmares, fear of sleep, selected sleep diary measures, and quality of life. The data were analysed using mixed models.Results: Adherence to STARS was high (dropout = 17.4%, average attended sessions = 77%) as was client satisfaction (MCSQ-4= 12.74, SDCSQ-4= 2.08). A medium to large significant effect of time was observed for insomnia severity (d = 0.96) and most secondary measures (except nightmares and fear of sleep). However, there was no significant interaction with condition at post-treatment for the primary outcome (d = 0.29) and most secondary outcomes; the only exceptions were increased coping with nightmares, decreased daytime sleep, and time in bed.Conclusions: STARS appears feasible for treating sleep disturbances in traumatized refugees in a routine clinical setting, showing moderate to large within-group effects. However, it was not superior to the waitlist, likely due to unexpected improvements in the waitlist group. Adjustments to STARS may enhance its efficacy. Further research is needed to determine how STARS can be a scalable add-on treatment for sleep disturbances in traumatized refugees and asylum seekers.Trial registration: German Clinical Trials Register identifier: DRKS00024419..

背景:睡眠障碍在创伤难民中非常普遍,尽管接受了治疗,但往往持续存在,需要适应的可扩展干预措施。“适应难民的睡眠训练”(STARS)小组干预是一种基于基于证据的睡眠障碍治疗(如CBT-I, IRT)的文化和情境敏感方法。本研究评估了STARS的可行性、可接受性和有效性。方法:在常规临床环境(DRKS-ID: DRKS00024419)中对47名年轻男性阿富汗难民进行了随机对照试验(STARS vs. waiting - list),并进行了前、后和3个月的随访评估。主要结局是失眠严重程度(失眠严重指数);次要结局包括创伤后应激障碍、焦虑和抑郁症状、噩梦、应对噩梦、睡眠恐惧、选定的睡眠日记测量和生活质量。使用混合模型对数据进行分析。结果:STARS的依从性很高(退出率为17.4%,平均参加次数为77%),客户满意度也很高(MCSQ-4 = 12.74, SDCSQ-4 = 2.08)。观察到时间对失眠严重程度(d = 0.96)和大多数次要测量(噩梦和睡眠恐惧除外)有中等到较大的显著影响。然而,主要结局(d = 0.29)和大多数次要结局与治疗后病情无显著相互作用;唯一的例外是应对噩梦的次数增加,白天睡眠时间减少,卧床时间减少。结论:STARS在常规临床环境中治疗创伤难民的睡眠障碍似乎是可行的,显示出中等到较大的组内效果。然而,它并不比等候名单优越,可能是由于等候名单组意想不到的改善。对STARS进行调整可能会增强其功效。需要进一步的研究来确定STARS如何成为创伤难民和寻求庇护者睡眠障碍的可扩展的附加治疗。试验注册:德国临床试验注册标识符:DRKS00024419..
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引用次数: 0
Association between methylmalonic acid and prevalence of depression in US adults: evidence from NHANES 2011-2014. 甲基丙二酸与美国成年人抑郁症患病率之间的关系:来自NHANES 2011-2014的证据
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-02-13 DOI: 10.1080/20008066.2025.2450109
Siqi Li, Wenbin Nan, Zhenyu Peng, Qiong Huang, Qiong Chen, Baimei He

Background: Depression is a prevalent mental disorder with high morbidity and mortality globally. Methylmalonic acid (MMA) is involved in the pathogenesis of numerous diseases. However, it is unclear whether there is an association between MMA and the prevalence of depression.Methods: This study enrolled 7866 US adults from the 2011-2014 survey of the National Health and Nutrition Examination Survey (NHANES). Individuals were categorized into depression group and non-depression group based on Patient's Health Questionnaire-9 (PHQ-9) score. The association between MMA concentrations and prevalence of depression was analysed by multivariate logistic and linear regression, restricted cubic spline regression, and subgroup analysis. Mediation analysis was used to explore the role of inflammation in the relationship between MMA and depression.Results: MMA concentrations were higher in participants with depression than those without depression. There was a positive and linear relationship of MMA concentrations with PHQ-9 score and depression risk, respectively. Moreover, the association was stable in most subgroups. Furthermore, inflammatory factors were positively correlated to MMA concentrations and prevalence of depression. In addition, white blood cell, neutrophil and alkaline phosphatase (ALP) mediated the relationship between MMA and depression.Conclusion: Our findings revealed that there was a linear and positive correlation between MMA and the prevalence of depression in US adults, which might be mediated by inflammation.

背景:抑郁症是一种普遍存在的精神障碍,在全球范围内具有很高的发病率和死亡率。甲基丙二酸(MMA)参与了许多疾病的发病机制。然而,目前尚不清楚MMA与抑郁症患病率之间是否存在关联。方法:本研究从2011-2014年美国国家健康与营养检查调查(NHANES)中招募了7866名美国成年人。根据患者健康问卷-9 (PHQ-9)得分将个体分为抑郁组和非抑郁组。MMA浓度与抑郁症患病率之间的关系通过多变量logistic和线性回归、限制三次样条回归和亚组分析进行分析。采用中介分析探讨炎症在MMA与抑郁关系中的作用。结果:抑郁症患者的MMA浓度高于无抑郁症患者。MMA浓度与PHQ-9评分和抑郁风险分别呈正相关和线性相关。此外,这种关联在大多数亚组中是稳定的。此外,炎症因子与MMA浓度和抑郁症患病率呈正相关。此外,白细胞、中性粒细胞和碱性磷酸酶(ALP)介导了MMA与抑郁症的关系。结论:我们的研究结果表明,MMA与美国成年人抑郁症患病率之间存在线性正相关,这可能是由炎症介导的。
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引用次数: 0
Construction and initial validation of the International Trauma Questionnaire - Caregiver Version (ITQ-CG): assessing ICD-11 PTSD and CPTSD in children from caregiver perspective. 国际创伤问卷-照顾者版(ITQ-CG)的构建和初步验证:从照顾者的角度评估ICD-11儿童PTSD和CPTSD。
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-05-06 DOI: 10.1080/20008066.2025.2493025
Alexander Haselgruber, Dina Weindl-Wagner, Andrea Zagaria, Karin Zajec, Judith Noske, Brigitte Lueger-Schuster

ABSTRACTObjective: The 11th version of the International Classification of Diseases (ICD-11) introduces Posttraumatic Stress Disorder (PTSD) and complex PTSD (CPTSD) as two distinct trauma-related disorders. The International Trauma Questionnaire (ITQ) is the most widely used measure of assessment and has been adapted for use in children and adolescents (ITQ-CA), but a corresponding caregiver version is still missing. We aimed to close this gap by adapting the ITQ-CA and provide an initial validation of the ITQ - Caregiver Version (ITQ-CG). A corresponding measure of assessment from caregiver-perspective is integral for the use in child psychology, psychiatry and research.Method: Altogether, 326 children and adolescents who attended the department of child and adolescent psychiatry were rated by their caregivers using a set of standardized measures. Excluding patients due to missing data or no trauma exposure, a final sample of 223 patients was analysed. Factorial structure of the ITQ-CG and multiple forms of validity were examined using confirmatory factor, latent class and correlation analysis.Results: Confirmatory factor analysis supported the two-factor higher-order model of ICD-11 CPTSD as the factorial structure of the ITQ-CG. Convergent-divergent validity of main- and subscales of the ITQ-CG was evidenced by respective correlations with criterion variables. Latent class analysis supported the discriminant validity of the ITQ-CG, identifying a CPTSD-, PTSD-, DSO- and low symptoms-class. The CPTSD-class was associated with highest rates of comorbid psychopathology and functional impairment. Concurrent validity was evidenced by satisfactory concordance between caregiver- and child-reports.Conclusion: This study provides the construction and initial validation of the ITQ-CG to assess ICD-11 PTSD and CPTSD in children and adolescents from caregiver-perspective. We found compelling evidence for the ITQ-CGs validity, identifying it as an easy-to-use screening instrument to assess ICD-11 PTSD and CPTSD from caregiver-perspective. The ITQ-CG is freely available for clinicians and researchers.

摘要目的:第11版国际疾病分类(ICD-11)将创伤后应激障碍(PTSD)和复杂创伤后应激障碍(CPTSD)作为两种不同的创伤相关疾病引入。国际创伤问卷(ITQ)是最广泛使用的评估措施,并已适用于儿童和青少年(ITQ- ca),但相应的护理人员版本仍然缺失。我们的目标是通过调整ITQ- ca来缩小这一差距,并提供ITQ-护理人员版本(ITQ- cg)的初步验证。从照顾者的角度评估的相应措施是不可或缺的,用于儿童心理学,精神病学和研究。方法:共有326名在儿童和青少年精神科就诊的儿童和青少年由其护理人员使用一套标准化的措施进行评分。排除数据缺失或无创伤暴露的患者,对223例患者的最终样本进行了分析。采用验证性因子、潜在类和相关分析对ITQ-CG的析因结构和多种形式的效度进行检验。结果:验证性因子分析支持ICD-11 CPTSD的双因素高阶模型作为ITQ-CG的因子结构。ITQ-CG主量表和子量表的收敛-发散效度分别与标准变量的相关性得到证明。潜在类别分析支持ITQ-CG的判别效度,确定了CPTSD-、PTSD-、DSO-和低症状类别。cptsd等级与最高的共病精神病理和功能障碍发生率相关。同时效度的证据是照料者和儿童报告之间令人满意的一致性。结论:本研究构建并初步验证了ITQ-CG从照顾者角度评估儿童青少年ICD-11 PTSD和CPTSD。我们为itq - cg的有效性找到了令人信服的证据,从护理者的角度将其确定为一种易于使用的筛查工具,用于评估ICD-11 PTSD和CPTSD。ITQ-CG可供临床医生和研究人员免费使用。
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引用次数: 0
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European Journal of Psychotraumatology
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