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Examining health literacy in the Danish general population: a cross-sectional study on the associations between individual factors and healthcare-seeking behaviour. 丹麦普通人群健康素养调查:关于个人因素与就医行为之间关系的横断面研究。
IF 3.7 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-01 DOI: 10.1093/eurpub/ckae150
Lisa Maria Sele Sætre, Dorte Ejg Jarbøl, Isabella Pernille Raasthøj, Sofie Amalie Seldorf, Sanne Rasmussen, Kirubakaran Balasubramaniam

Knowledge about health literacy challenges among the general population is valuable for initiatives targeting social inequity in health. We investigated health literacy in various population groups and the impact of healthcare-seeking behaviour by analysing the associations between (i) lifestyle, socioeconomics, self-rated health, chronic disease, and health literacy and (ii) symptom burden, contact to general practitioner (GP), and health literacy. In total, 27 488 individuals participated in a population-based survey. Questionnaire data comprised information about symptoms, GP contact, lifestyle, self-rated health, chronic disease, and four aspects of health literacy: feeling understood and supported by healthcare providers, having sufficient information about health, having social support for health, and being able to actively engage with healthcare providers. Socioeconomics were obtained from registers. Descriptive statistics and multivariable linear regression models were applied. Individuals who smoked, lived alone, had different ethnicity than Danish, and low self-rated health had more health literacy challenges reflected in lower scores for all aspects of health literacy. Individuals with high symptom burden and those who had presented a high absolute number of symptoms to their GP were less likely to have sufficient information about health and be able to actively engage, whereas individuals reporting GP contact with a high relative percentage of their symptoms were more likely to feel understood and supported by healthcare providers. Health literacy challenges are related to healthcare-seeking behaviour and several individual factors. To address social inequity in health and society, interventions aimed at both the individual and community-based health literacy are essential.

了解普通人群在健康素养方面所面临的挑战,对于针对社会健康不平等问题采取相应措施非常有价值。我们通过分析(i)生活方式、社会经济、自我健康评价、慢性病和健康素养之间的关联,以及(ii)症状负担、与全科医生(GP)的联系和健康素养之间的关联,调查了不同人群的健康素养以及对医疗行为的影响。共有 27 488 人参与了一项基于人口的调查。问卷数据包括症状、与全科医生的联系、生活方式、自我健康评价、慢性病以及健康素养四个方面的信息:感受到医疗服务提供者的理解和支持、拥有足够的健康信息、在健康方面获得社会支持以及能够积极与医疗服务提供者联系。社会经济情况来自登记册。采用了描述性统计和多变量线性回归模型。吸烟、独居、种族与丹麦人不同以及自我健康评价较低的人在健康素养方面面临更多挑战,这反映在他们在健康素养各方面的得分都较低。症状负担重的人和向全科医生反映症状绝对数高的人不太可能获得足够的健康信息,也不太可能积极地参与,而向全科医生反映症状相对比例高的人则更有可能感受到医疗服务提供者的理解和支持。健康素养方面的挑战与寻求医疗保健的行为和一些个人因素有关。要解决健康和社会中的社会不平等问题,针对个人和社区健康素养的干预措施至关重要。
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引用次数: 0
Health perceptions of adverse weather in older adults in England: analysis of 2019/20 survey data. 英格兰老年人对恶劣天气的健康感知:2019/20 年度调查数据分析。
IF 3.7 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-01 DOI: 10.1093/eurpub/ckae153
Grace Anne Turner, Agostinho Moreira de Sousa, Emer O'Connell, Sari Kovats, Katya Brooks, Owen Landeg, Sharif Ismail, Anusha Rajamani, Shakoor Hajat

Risks to older adults (OA) (aged 65+ years) associated with hot and cold weather in the UK are well-documented. The study aim is to explore OA perception of health risks from high and low temperatures, health-protective measures undertaken, and implications for public health messaging. In 2019/20, Ipsos MORI conducted face-to-face surveys with OA in England (n = 461 cold weather survey, n = 452 hot weather survey). Participants reported temperature-related symptoms, risk perceptions for different groups, and behaviours during hot and cold weather. Analysis involved binomial logistic regression models to assess potential factors (demographics, vulnerability, behaviours) associated with older adults' health risk perception in hot and cold weather. Less than half of OA in both surveys agreed that hot or cold weather posed a risk to their health. OA with higher education, annual income >£25 000 or home ownership were less likely to perceive their health at risk during cold weather and regional differences in hot weather were identified. OA who recognized those the same age or living alone as at an increased risk were more likely to perceive their own health as at risk. OA were more likely to self-identify health risks when reporting those aged 65 yrs+ to be at an increased risk in cold weather. Various temperature-related protective behaviours were associated with older adults' risk perception in hot and cold weather. These findings provide evidence for public health agencies to target high risk individuals, and modify temperature-related public health messaging to protect OA.

英国老年人(OA)(65 岁以上)与炎热和寒冷天气相关的风险已得到充分证实。本研究旨在探讨 OA 对高温和低温带来的健康风险的看法、采取的健康保护措施以及对公共卫生信息的影响。2019/20 年,Ipsos MORI 在英格兰对 OA 进行了面对面调查(n = 461 次寒冷天气调查,n = 452 次炎热天气调查)。参与者报告了与温度有关的症状、不同群体的风险认知以及在炎热和寒冷天气中的行为。分析采用二项逻辑回归模型,以评估与老年人在炎热和寒冷天气中的健康风险感知相关的潜在因素(人口统计学、脆弱性、行为)。在两次调查中,只有不到一半的 OA 同意炎热或寒冷的天气会对他们的健康构成风险。受过高等教育、年收入超过 25 000 英镑或拥有住房的老年人不太可能在寒冷天气中认为自己的健康受到威胁,而且在炎热天气中也存在地区差异。认为同龄人或独居者健康风险增加的 OA 更有可能认为自己的健康面临风险。当报告 65 岁以上的老年人在寒冷天气中健康风险增加时,OA 更有可能自我识别健康风险。各种与温度有关的保护行为与老年人在炎热和寒冷天气中的风险认知有关。这些发现为公共卫生机构锁定高风险人群、修改与温度相关的公共卫生信息以保护 OA 提供了证据。
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引用次数: 0
Is the period of austerity in the UK associated with increased rates of adverse birth outcomes? 英国的财政紧缩时期是否与不良出生结果率上升有关?
IF 3.7 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-01 DOI: 10.1093/eurpub/ckae154
Rachael Watson, David Walsh, Sonya Scott, Jade Carruthers, Lynda Fenton, Gerry McCartney, Emily Moore

Hugely concerning changes to health outcomes have been observed in the UK since the early 2010s, including reductions in life expectancy and widening of inequalities. These have been attributed to UK Government 'austerity' policies which have profoundly affected poorer populations. Studies in mainland Europe have shown associations between austerity and increases in adverse birth outcomes such as low birthweight (LBW). The aim here was to establish whether the period of UK austerity was also associated with higher risks of such outcomes. We analysed all live births in Scotland between 1981 and 2019 (n = 2.3 million), examining outcomes of LBW, preterm birth (PB) and small-for-gestational-age (SGA). Descriptive trend analyses, segmented regression (to identify changes in trends) and logistic regression modelling (to compare risk of outcomes between time periods) were undertaken, stratified by infant sex and quintiles of socioeconomic deprivation. There were marked increases in LBW and PB rates in the austerity period, particularly in the most deprived areas. However, rates of SGA decreased, suggesting prematurity as the main driver of LBW rather than intrauterine growth restriction. The regression analyses confirmed these results: trends in LBW and PB changed within 1-3 years of the period in which austerity was first implemented, and that period was associated with higher risk of such outcomes in adjusted models. The results add to the European evidence base of worsening birth outcomes associated with austerity-related economic adversity. The newly elected UK government needs to understand the causes of these changes, and the future implications for child and adult health.

自 2010 年代初以来,英国的健康状况发生了令人担忧的巨大变化,包括预期寿命缩短和不平等现象扩大。这些都归咎于英国政府的 "紧缩 "政策,这些政策对贫困人口产生了深远的影响。欧洲大陆的研究表明,紧缩政策与出生体重不足(LBW)等不良出生结果的增加有关。本文旨在确定英国的财政紧缩时期是否也与此类结果的高风险有关。我们分析了 1981 年至 2019 年期间苏格兰的所有活产婴儿(n = 230 万),研究了低出生体重儿、早产儿 (PB) 和小于胎龄儿 (SGA) 的结果。按照婴儿性别和社会经济贫困程度的五分位数进行了描述性趋势分析、分段回归(以确定趋势的变化)和逻辑回归建模(以比较不同时期的结果风险)。在紧缩时期,低体重儿和早产儿的比率明显上升,尤其是在最贫困地区。然而,SGA 的比率却有所下降,这表明早产是造成低体重儿的主要原因,而不是宫内生长受限。回归分析证实了这些结果:在开始实施紧缩政策的 1-3 年内,低体重儿和早产儿的趋势发生了变化,在调整后的模型中,这一时期发生此类结果的风险较高。这些结果增加了欧洲的证据基础,即与紧缩相关的经济逆境会导致出生结果恶化。新当选的英国政府需要了解这些变化的原因,以及未来对儿童和成人健康的影响。
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引用次数: 0
Child poverty-a political choice. 儿童贫困是一个政治选择。
IF 3.7 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-01 DOI: 10.1093/eurpub/ckae138
Anna Pearce, Alastair H Leyland
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引用次数: 0
Educational differences in alcohol-related morbidity and the role of working conditions: a Swedish register-based cohort study. 与酒精有关的发病率的教育差异和工作条件的作用:一项基于瑞典登记簿的队列研究。
IF 3.7 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-01 DOI: 10.1093/eurpub/ckae158
Melody Almroth, Tomas Hemmingsson, Daniel Falkstedt, Emma Carlsson, Katarina Kjellberg, Emelie Thern

This study aims to investigate the relationship between education and alcohol-related morbidity and the role that low job control and heavy physical workload play in explaining these associations among men and women in Sweden. This register-based cohort study (SWIP cohort) includes over three million individuals registered in Sweden in 2005. Job control and physical workload were measured using a job exposure matrix linked to the index person based on their registered occupation at baseline. Alcohol-related morbidity was measured through diagnoses in the national patient registers between 2006 and 2020. Cox proportional hazards regression models were built to estimate associations between education and alcohol-related morbidity. Reductions in hazard ratios (HRs) were calculated after adjusting for job control, physical workload, and other covariates. Models were also stratified by sex. Lower levels of education predicted a higher risk of alcohol-related morbidity (HR: 2.55 95% confidence interval: 2.49-2.62 for the lowest educated compared to the highest). Low job control and heavy physical workload both played roles in explaining educational differences in alcohol-related morbidity even after accounting for sociodemographic and health factors (15.1% attenuation for job control and 18.3% for physical workload among the lowest educated). Physical workload explained a larger proportion of the associations among men compared to women. Lower levels of education were associated with an increased risk of alcohol-related morbidity and working conditions partly explained these associations beyond what was explained by sociodemographic and health factors. Improving working conditions could therefore prevent some cases of alcohol-related morbidity.

本研究旨在调查瑞典男性和女性受教育程度与酒精相关发病率之间的关系,以及低工作控制力和繁重体力劳动在解释这些关联方面所起的作用。这项基于登记的队列研究(SWIP 队列)包括 2005 年在瑞典登记的 300 多万人。工作控制和体力劳动负荷是根据基线时登记的职业,通过与指数人物相关联的工作暴露矩阵进行测量的。与酒精有关的发病率是通过 2006 年至 2020 年间全国患者登记册中的诊断结果来衡量的。我们建立了 Cox 比例危险回归模型来估计教育与酒精相关发病率之间的关系。在对工作控制、体力工作量和其他协变量进行调整后,计算出危险比(HRs)的降低情况。模型还按性别进行了分层。教育程度越低,酒精相关发病风险越高(与教育程度最高者相比,教育程度最低者的危险比为 2.55,95% 置信区间为 2.49-2.62)。即使考虑了社会人口因素和健康因素,工作控制力低和体力工作量大仍能解释酒精相关发病率的教育差异(教育程度最低者的工作控制力下降了 15.1%,体力工作量下降了 18.3%)。与女性相比,体力工作量在男性中的关联比例更大。教育程度越低,与酒精相关的发病风险越高,而工作条件在一定程度上解释了这些关联,超出了社会人口和健康因素所能解释的范围。因此,改善工作条件可以预防某些与酒精相关的发病率。
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引用次数: 0
All-cause and cause-specific mortality among older migrant and non-migrant adults in Finland: a register study on all deaths, 2002-2020. 芬兰老年移民和非移民成年人的全因和特定原因死亡率:2002-2020 年所有死亡登记研究。
IF 3.7 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-01 DOI: 10.1093/eurpub/ckae159
Laura Kemppainen, Teemu Kemppainen, Jani Raitanen, Mari Aaltonen, Leena Forma, Anne Kouvonen, Jutta Pulkki

Migrant mortality advantage is established in various studies, but there is a lack of evidence on migrant mortality trends in old age. Previous studies have primarily concentrated on all-cause mortality, and few include older age groups. Discussions about the migrant mortality advantage continue due to concerns about data availability and accuracy. Additionally, the mechanisms explaining the migrant mortality advantage remain unclear. This study examines all-cause and cause-specific mortality among older migrant and nonmigrant adults aged 70 and above using Finnish Cause of Death register data (2002-20) and the corresponding risk population. We investigate differences in overall and cause-specific mortality between migrant and Finnish-born population and by geographical region of origin. We calculated direct age-standardized mortality rates and age group-specific death rates followed by Poisson regression to study relative mortality differences. Age at death, sex, income, region of residence, and year of death were controlled for in the regression analysis. We found evidence of migrant mortality advantage across various causes of death, but there was variation by regions of origin groups and sex. Notably, women exhibit the strongest advantage in respiratory and digestive system diseases, while men demonstrated pronounced advantages in external causes and respiratory diseases. Our study challenges the notion of a general diminishing healthy migrant effect in old age. Our findings emphasize the need for nuanced investigations into socioeconomic factors and tailored interventions for older migrants.

各种研究都证实了移民在死亡率方面的优势,但缺乏有关移民老年死亡率趋势的证据。以往的研究主要集中于全因死亡率,很少有研究包括老年群体。由于对数据可用性和准确性的担忧,有关移民死亡率优势的讨论仍在继续。此外,解释移民死亡率优势的机制仍不清楚。本研究利用芬兰死因登记数据(2002-20 年)和相应的风险人群,研究了 70 岁及以上老年移民和非移民成年人的全因和特定原因死亡率。我们调查了移民和芬兰出生人口之间以及不同原籍地区之间在总死亡率和特定病因死亡率方面的差异。我们计算了直接年龄标准化死亡率和特定年龄组死亡率,然后进行泊松回归,以研究相对死亡率差异。回归分析中对死亡年龄、性别、收入、居住地区和死亡年份进行了控制。我们发现有证据表明,在各种死因中,移民的死亡率都具有优势,但不同地区的原籍群体和性别之间存在差异。值得注意的是,女性在呼吸系统和消化系统疾病方面表现出最强的优势,而男性则在外部原因和呼吸系统疾病方面表现出明显的优势。我们的研究对健康移民效应在老年普遍减弱的观点提出了质疑。我们的研究结果强调,有必要对社会经济因素进行细致入微的调查,并为老年移民量身定制干预措施。
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引用次数: 0
Changes in perceived neighborhood social cohesion and self-assessed health: 17-year follow-up of the Dutch GLOBE study. 邻里社会凝聚力和自我健康评估的变化:荷兰 GLOBE 研究的 17 年跟踪调查。
IF 3.7 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-01 DOI: 10.1093/eurpub/ckae168
Vernon Cail, Joost Oude Groeniger, Mariëlle A Beenackers, Frank J van Lenthe

Prior research has indicated that residents who perceive their neighborhood as more cohesive have better mental and physical health than those with lower perceived neighborhood social cohesion. However, because most studies are based on cross-sectional data, it remains unclear whether improving the perceptions of social cohesion leads to better health over time. This study applied random effects within-between models to examine the within-individual and between-individual associations of perceived neighborhood social cohesion and poor self-assessed health (SAH) in a cohort of Dutch adults with 17-year follow-up. We also tested whether such associations varied by age, educational level, and gender. The results of pooled analyses indicated that higher perceived neighborhood social cohesion was associated with better SAH [odds ratio (OR): 0.72; 95% confidence interval (CI): 0.65, 0.80], but did not find conclusive evidence that within-individual changes in perceived neighborhood social cohesion were associated with SAH (OR: 0.96; 95% CI: 0.89, 1.04). We also did not observe any moderating effects for age, educational level, or gender. This study provides some evidence that improving social cohesion in neighborhoods may be a beneficial health promotion strategy.

先前的研究表明,认为邻里更有凝聚力的居民比认为邻里社会凝聚力较低的居民拥有更好的身心健康。然而,由于大多数研究都是基于横截面数据,因此,社会凝聚力感知的改善是否会随着时间的推移带来更好的健康状况,目前仍不清楚。本研究采用随机效应之间模型,在对荷兰成年人进行了长达 17 年的跟踪调查后,对感知邻里社会凝聚力与自我评估健康状况(SAH)之间的个体内和个体间关系进行了研究。我们还检验了这种关联是否因年龄、教育水平和性别而异。汇总分析结果表明,感知邻里社会凝聚力越高,自我评估健康状况越好[几率比(OR):0.72;95% 置信区间(CI):0.65, 0.80],但没有发现确凿证据表明感知邻里社会凝聚力的个体内部变化与自我评估健康状况有关(OR:0.96;95% CI:0.89, 1.04)。我们也没有观察到年龄、教育水平或性别的调节作用。本研究提供了一些证据,表明提高邻里社会凝聚力可能是一种有益的健康促进策略。
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引用次数: 0
Constructing a One Health governance architecture: a systematic review and analysis of governance mechanisms for One Health. 构建 "一个健康 "治理架构:对 "一个健康 "治理机制的系统审查和分析。
IF 3.7 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-01 DOI: 10.1093/eurpub/ckae124
Darlington David Faijue, Allison Osorio Segui, Kalpita Shringarpure, Ahmed Razavi, Nadeem Hasan, Osman Dar, Logan Manikam

The integration of human, animal, and environmental health in the One Health framework is crucial for tackling complex health and environmental issues. Governance structures in One Health initiatives are essential for coordinating efforts, fostering partnerships, and establishing effective policy frameworks. This systematic review, registered with PROSPERO, aims to evaluate governance architectures in One Health initiatives. Searches in PubMed, Scopus, WoS, and Cochrane from 2000 to 2023 were conducted. Key terms focused on peer-reviewed articles, systematic reviews, and relevant grey literature. Nine eligible studies were selected based on inclusion criteria. Data synthesis aimed to assess governance mechanisms' functionality and effectiveness. Among 1277 sources screened, nine studies across diverse regions were eligible. An adapted framework assessed implementation mechanisms of international agreements, categorizing them into Engagement, Coordination, Policies, and Financial domains. The findings highlight the importance of effective governance, stakeholder engagement, and collaborative approaches in addressing One Health's challenges. Identified challenges include deficient intersectoral collaboration, funding constraints, and stakeholder conflicts. Robust governance frameworks are pivotal in One Health paradigms, emphasizing stakeholder engagement and collaboration. These insights guide policymakers, practitioners, and researchers in refining governance structures to enhance human-animal health and environmental sustainability. Acknowledging study limitations, such as methodological variations and limited geographical scope, underscores the importance of further research in this area.

将人类、动物和环境健康纳入 "一体健康 "框架对于解决复杂的健康和环境问题至关重要。一体健康 "倡议中的治理结构对于协调工作、促进伙伴关系和建立有效的政策框架至关重要。本系统综述已在 PROSPERO 注册,旨在评估 "一体健康 "倡议中的治理结构。我们在 PubMed、Scopus、WoS 和 Cochrane 中检索了 2000 年至 2023 年的资料。关键词侧重于同行评审文章、系统综述和相关灰色文献。根据纳入标准筛选出 9 项符合条件的研究。数据综合旨在评估治理机制的功能性和有效性。在筛选出的 1277 个资料来源中,有 9 项跨地区的研究符合条件。经过调整的框架评估了国际协定的实施机制,将其分为参与、协调、政策和财务领域。研究结果强调了有效治理、利益相关者参与和合作方法在应对 "一个健康 "挑战中的重要性。已确定的挑战包括部门间合作不足、资金限制和利益相关者冲突。健全的治理框架在 "一体健康 "范例中至关重要,强调利益相关者的参与和协作。这些见解可指导政策制定者、从业人员和研究人员完善治理结构,以提高人与动物的健康水平和环境的可持续性。承认研究的局限性,如方法上的差异和有限的地理范围,强调了在这一领域开展进一步研究的重要性。
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引用次数: 0
The Community Acute Respiratory Infection surveillance programme: an evaluation of a newly established surveillance programme in Scotland. 社区急性呼吸道感染监测方案:对苏格兰新建立的监测方案的评价。
IF 3.7 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-11-28 DOI: 10.1093/eurpub/ckae200
Tonje S Laird, Mark Hamilton, Catriona Oliver, Fatima Sadiq, Yomna Moawad, Josie Evans

The Community Acute Respiratory Infection (CARI) surveillance programme, established by Public Health Scotland (PHS) in November 2021, aims to monitor respiratory infections in communities, replacing prior schemes to ensure early detection of outbreaks and inform public health interventions. Positioned as a cornerstone of PHS's national infectious respiratory diseases plan, CARI is pivotal for safeguarding public health. This study presents key findings from the 2022/23 CARI season and evaluates the programme's performance during this period. CARI uses a network of sentinel general practitioner (GP) practices across Scotland to monitor patients with acute respiratory infection symptoms, employing multiplex polymerase chain reaction testing for 10 common pathogens. Results are linked to enhanced surveillance data, providing insights into infection trends during the season. The evaluation comprised an online GP survey and a quantitative assessment of programme performance. In the 2022/23 season, 180 GP practices participated in CARI, testing 15,823 samples. Swab positivity peaked in December 2022, driven by a large spike in influenza A activity. The evaluation showed that CARI is highly useful, with positive feedback on simplicity, flexibility, and acceptability. Representativeness varied across health boards and age groups. Despite occasional laboratory processing delays, data quality remained good, with timely reporting and stable participation. CARI reflected patterns in infections observed in secondary care in Scotland and Europe, providing valuable insights into disease patterns and impact. It also provided timely intelligence to key decision-makers, enabling prompt public health response. Changes for the 2023/24 season aim to further optimize the programme.

苏格兰公共卫生部于2021年11月制定了社区急性呼吸道感染监测方案,旨在监测社区的呼吸道感染,取代以前的计划,确保及早发现疫情,并为公共卫生干预提供信息。CARI被定位为PHS国家传染性呼吸道疾病计划的基石,是保障公众健康的关键。本研究介绍了2022/23年CARI季节的主要发现,并评估了该计划在此期间的表现。CARI使用遍布苏格兰的哨兵全科医生(GP)实践网络来监测急性呼吸道感染症状的患者,采用10种常见病原体的多重聚合酶链反应测试。结果与加强的监测数据相关联,提供了对季节感染趋势的见解。评估包括一项在线GP调查和对项目绩效的定量评估。在2022/23赛季,180个GP实践参与了CARI,测试了15,823个样本。在甲型流感活动大幅增加的推动下,拭子阳性在2022年12月达到峰值。评价表明,CARI是非常有用的,在简单性、灵活性和可接受性方面得到了积极的反馈。各卫生委员会和各年龄组的代表性各不相同。尽管偶尔有实验室处理延迟,但数据质量保持良好,报告及时,参与稳定。CARI反映了在苏格兰和欧洲二级保健中观察到的感染模式,为疾病模式和影响提供了有价值的见解。它还向关键决策者提供了及时的情报,使其能够迅速作出公共卫生反应。2023/24赛季的变化旨在进一步优化节目。
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引用次数: 0
Prevalent findings on low-dose CT scan lung cancer screening: a French prospective pilot study. 低剂量 CT 扫描肺癌筛查的普遍发现:一项法国前瞻性试点研究。
IF 3.7 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-11-20 DOI: 10.1093/eurpub/ckae183
Philippe A Grenier, Maxence Arutkin, Anne Laure Brun, Anne-Cécile Métivier, Edouard Sage, Franck Haziza, Félix Ackermann, François Mellot, Alexandre Vallée

Despite significant therapeutic advances, lung cancer remains the biggest killer among cancers. In France, there is no national screening program against lung cancer. Thus, in this perspective, the Foch Hospital decided to implement a pilot and clinical low-dose CT screening program to evaluate the efficiency of such screening. The purpose of this study was to describe the prevalent findings of this low-dose CT screening program. Participants were recruited in the screening program through general practitioners (GPs), pharmacists, and specialists from June 2023 to June 2024. The inclusion criteria included male or female participants aged 50 to 80 years, current smokers or former smokers who had quit less than 15 years prior, with a smoking history of over 20 pack-years. Chest CT scans were conducted at Foch Hospital using a low-dose CT protocol based on volume mode with a multi-slice scanner (≥60 slices) without contrast injection. In total, 477 participants were recruited in the CT scan screening, 235 (49%) were males with a median age of 60 years [56-67] and 35 smoke pack-years [29-44] and 242 females (51%) with a median age of 60 years [55-60] and 30 smoke pack-years [25-40]. Eight participants showed positive nodules on CT scan, as a 1.7% rate. 66.7% of diagnosed cancers were in early stages (0-I). It is feasible to implement structured lung cancer screening using low-dose CT in a real-world setting among the general population. This approach successfully identifies most early-stage cancers that could be treated curatively.

尽管在治疗方面取得了重大进展,但肺癌仍然是癌症中的最大杀手。法国没有全国性的肺癌筛查计划。因此,福煦医院决定实施一项低剂量 CT 筛查试点和临床项目,以评估此类筛查的效率。本研究的目的是描述该低剂量 CT 筛查项目的主要结果。2023 年 6 月至 2024 年 6 月期间,该筛查项目通过全科医生(GP)、药剂师和专科医生招募参与者。纳入标准包括 50 至 80 岁的男性或女性参与者、当前吸烟者或戒烟少于 15 年的前吸烟者、吸烟史超过 20 包年。胸部CT扫描在福煦医院进行,采用基于容积模式的低剂量CT方案,使用多层扫描仪(≥60片),不注射造影剂。共有 477 人参加了 CT 扫描筛查,其中男性 235 人(49%),中位年龄为 60 岁[56-67]和 35 个烟包年[29-44];女性 242 人(51%),中位年龄为 60 岁[55-60]和 30 个烟包年[25-40]。8 名参与者在 CT 扫描中发现了阳性结节,比例为 1.7%。66.7%的确诊癌症处于早期阶段(0-I期)。在普通人群中使用低剂量 CT 进行结构性肺癌筛查是可行的。这种方法能成功识别大多数可进行根治性治疗的早期癌症。
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European Journal of Public Health
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