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Constructing a One Health governance architecture: a systematic review and analysis of governance mechanisms for One Health. 构建 "一个健康 "治理架构:对 "一个健康 "治理机制的系统审查和分析。
IF 3.7 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-01 DOI: 10.1093/eurpub/ckae124
Darlington David Faijue, Allison Osorio Segui, Kalpita Shringarpure, Ahmed Razavi, Nadeem Hasan, Osman Dar, Logan Manikam

The integration of human, animal, and environmental health in the One Health framework is crucial for tackling complex health and environmental issues. Governance structures in One Health initiatives are essential for coordinating efforts, fostering partnerships, and establishing effective policy frameworks. This systematic review, registered with PROSPERO, aims to evaluate governance architectures in One Health initiatives. Searches in PubMed, Scopus, WoS, and Cochrane from 2000 to 2023 were conducted. Key terms focused on peer-reviewed articles, systematic reviews, and relevant grey literature. Nine eligible studies were selected based on inclusion criteria. Data synthesis aimed to assess governance mechanisms' functionality and effectiveness. Among 1277 sources screened, nine studies across diverse regions were eligible. An adapted framework assessed implementation mechanisms of international agreements, categorizing them into Engagement, Coordination, Policies, and Financial domains. The findings highlight the importance of effective governance, stakeholder engagement, and collaborative approaches in addressing One Health's challenges. Identified challenges include deficient intersectoral collaboration, funding constraints, and stakeholder conflicts. Robust governance frameworks are pivotal in One Health paradigms, emphasizing stakeholder engagement and collaboration. These insights guide policymakers, practitioners, and researchers in refining governance structures to enhance human-animal health and environmental sustainability. Acknowledging study limitations, such as methodological variations and limited geographical scope, underscores the importance of further research in this area.

将人类、动物和环境健康纳入 "一体健康 "框架对于解决复杂的健康和环境问题至关重要。一体健康 "倡议中的治理结构对于协调工作、促进伙伴关系和建立有效的政策框架至关重要。本系统综述已在 PROSPERO 注册,旨在评估 "一体健康 "倡议中的治理结构。我们在 PubMed、Scopus、WoS 和 Cochrane 中检索了 2000 年至 2023 年的资料。关键词侧重于同行评审文章、系统综述和相关灰色文献。根据纳入标准筛选出 9 项符合条件的研究。数据综合旨在评估治理机制的功能性和有效性。在筛选出的 1277 个资料来源中,有 9 项跨地区的研究符合条件。经过调整的框架评估了国际协定的实施机制,将其分为参与、协调、政策和财务领域。研究结果强调了有效治理、利益相关者参与和合作方法在应对 "一个健康 "挑战中的重要性。已确定的挑战包括部门间合作不足、资金限制和利益相关者冲突。健全的治理框架在 "一体健康 "范例中至关重要,强调利益相关者的参与和协作。这些见解可指导政策制定者、从业人员和研究人员完善治理结构,以提高人与动物的健康水平和环境的可持续性。承认研究的局限性,如方法上的差异和有限的地理范围,强调了在这一领域开展进一步研究的重要性。
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引用次数: 0
The Community Acute Respiratory Infection surveillance programme: an evaluation of a newly established surveillance programme in Scotland. 社区急性呼吸道感染监测方案:对苏格兰新建立的监测方案的评价。
IF 3.7 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-11-28 DOI: 10.1093/eurpub/ckae200
Tonje S Laird, Mark Hamilton, Catriona Oliver, Fatima Sadiq, Yomna Moawad, Josie Evans

The Community Acute Respiratory Infection (CARI) surveillance programme, established by Public Health Scotland (PHS) in November 2021, aims to monitor respiratory infections in communities, replacing prior schemes to ensure early detection of outbreaks and inform public health interventions. Positioned as a cornerstone of PHS's national infectious respiratory diseases plan, CARI is pivotal for safeguarding public health. This study presents key findings from the 2022/23 CARI season and evaluates the programme's performance during this period. CARI uses a network of sentinel general practitioner (GP) practices across Scotland to monitor patients with acute respiratory infection symptoms, employing multiplex polymerase chain reaction testing for 10 common pathogens. Results are linked to enhanced surveillance data, providing insights into infection trends during the season. The evaluation comprised an online GP survey and a quantitative assessment of programme performance. In the 2022/23 season, 180 GP practices participated in CARI, testing 15,823 samples. Swab positivity peaked in December 2022, driven by a large spike in influenza A activity. The evaluation showed that CARI is highly useful, with positive feedback on simplicity, flexibility, and acceptability. Representativeness varied across health boards and age groups. Despite occasional laboratory processing delays, data quality remained good, with timely reporting and stable participation. CARI reflected patterns in infections observed in secondary care in Scotland and Europe, providing valuable insights into disease patterns and impact. It also provided timely intelligence to key decision-makers, enabling prompt public health response. Changes for the 2023/24 season aim to further optimize the programme.

苏格兰公共卫生部于2021年11月制定了社区急性呼吸道感染监测方案,旨在监测社区的呼吸道感染,取代以前的计划,确保及早发现疫情,并为公共卫生干预提供信息。CARI被定位为PHS国家传染性呼吸道疾病计划的基石,是保障公众健康的关键。本研究介绍了2022/23年CARI季节的主要发现,并评估了该计划在此期间的表现。CARI使用遍布苏格兰的哨兵全科医生(GP)实践网络来监测急性呼吸道感染症状的患者,采用10种常见病原体的多重聚合酶链反应测试。结果与加强的监测数据相关联,提供了对季节感染趋势的见解。评估包括一项在线GP调查和对项目绩效的定量评估。在2022/23赛季,180个GP实践参与了CARI,测试了15,823个样本。在甲型流感活动大幅增加的推动下,拭子阳性在2022年12月达到峰值。评价表明,CARI是非常有用的,在简单性、灵活性和可接受性方面得到了积极的反馈。各卫生委员会和各年龄组的代表性各不相同。尽管偶尔有实验室处理延迟,但数据质量保持良好,报告及时,参与稳定。CARI反映了在苏格兰和欧洲二级保健中观察到的感染模式,为疾病模式和影响提供了有价值的见解。它还向关键决策者提供了及时的情报,使其能够迅速作出公共卫生反应。2023/24赛季的变化旨在进一步优化节目。
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引用次数: 0
Effort-reward imbalance and burnout among German school leaders. Representative study findings and implications for an underserved occupational group. 德国学校领导的努力-回报失衡与倦怠。代表性的研究结果和对服务不足的职业群体的影响。
IF 3.7 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-11-28 DOI: 10.1093/eurpub/ckae182
Nele Groß, Kevin Dadaczynski, Marcus Pietsch

This study examines the relationship between gratification crisis and burnout syndrome in German school leaders and explores how sociodemographic and school-level factors relate to burnout. Additionally, it investigates how these factors influence the likelihood of experiencing burnout and engagement based on sociodemographic and school characteristics. The research design focuses on the relationship between the effort-reward imbalance (ERI) model and latent profiles of the Maslach Burnout Inventory. Statistical analyses include group comparisons and logistic regression to examine the relationships between variables, such as ERI and sociodemographic and school-level characteristics. The ERI ratio significantly associated with burnout, indicating higher risk as the ratio rises. Sociodemographic and school-level factors showed significant variations by student numbers and school type. Regression models revealed a positive relationship between ERI and burnout, while age negatively correlated, suggesting lower burnout risk in older leaders. Logistic regression highlighted associations between age, gender, and engagement, with increasing age positively associated with engagement and lower ERI scores associated with higher engagement. The results of the study demonstrate a significant relationship between perceived reward crisis as measured by the ERI model and burnout syndrome among school leaders in Germany. School leaders who feel undervalued and overburdened are more susceptible to burnout. The reported ERI depends on specific contextual variables, including the type of school, the number of students, and the age of the school principal. It is important for schools and educational institutions to address the multiple factors that influence burnout and work engagement among school leaders.

本研究考察了德国学校领导满足感危机与职业倦怠的关系,并探讨了社会人口统计学和学校层面因素与职业倦怠的关系。此外,它还调查了这些因素如何影响基于社会人口学和学校特征的经历倦怠和投入的可能性。本研究旨在探讨努力-报酬不平衡(ERI)模型与Maslach倦怠量表潜在特征的关系。统计分析包括组比较和逻辑回归,以检查变量之间的关系,如ERI和社会人口统计学和学校水平特征。ERI比率与职业倦怠显著相关,表明该比率越高,风险越高。社会人口学和校级因素因学生人数和学校类型而有显著差异。回归模型显示ERI与职业倦怠呈正相关,而年龄呈负相关,表明年龄较大的领导者职业倦怠风险较低。逻辑回归强调了年龄、性别和敬业度之间的关联,年龄的增长与敬业度呈正相关,而ERI得分越低,敬业度越高。研究结果表明,在德国的学校领导中,ERI模型测量的感知奖励危机与倦怠综合症之间存在显著的关系。感觉自己被低估和负担过重的学校领导更容易倦怠。报告的ERI取决于具体的环境变量,包括学校类型、学生人数和校长年龄。对于学校和教育机构来说,解决影响学校领导职业倦怠和工作投入的多重因素是很重要的。
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引用次数: 0
Could digital twins be the next revolution in healthcare? 数字双胞胎会成为医疗保健领域的下一次革命吗?
IF 3.7 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-11-27 DOI: 10.1093/eurpub/ckae191
Leonardo de Oliveira El-Warrak, Claudio Miceli de Farias

A Digital Twin (DT) can be understood as a representation of a real asset, a virtual replica of a physical object, process, or even a system. They have been used in managing healthcare facilities, streamlining care processes, personalizing treatments, and enhancing patient recovery. The potential impact of this tool on our society and its well-being is quite significant. A quick review of the literature was carried out using the terms ('Digital Twins') and ('Digital Health'), and (Health Care) with a time interval of up to 5 years (2018-23). Using the PRISMA Method, the search was conducted in six academic databases: IEEE Xplore, Dimensions, Scopus, Web of Science, PubMed, and ACM. After applying the search strings and the exclusion criteria, a total of 13 publications were identified and listed to constitute and support the discussion of this article. The selected studies were categorized into 2 groups according to their application in healthcare: A group of clinical applications, subdivided into topics on personalized care and reproduction of biological structures and another group of operational applications, subdivided into topics such as optimization of operational processes, reproduction of physical structures, and development of devices and drugs. The use of DT in healthcare presents important challenges related to data integration, privacy, and interoperability. However, trends indicate exciting potential in personalizing treatment, prevention, remote monitoring, informed decision-making, and process management, which can result in significant improvements in quality and efficiency in healthcare.

数字孪生(DT)可以理解为真实资产的代表,是物理对象、流程甚至系统的虚拟复制品。它们已被用于管理医疗设施、简化护理流程、个性化治疗和促进病人康复。这一工具对我们的社会及其福祉的潜在影响相当大。我们使用("数字双胞胎")、("数字健康")和(医疗保健)等术语对文献进行了快速综述,时间间隔最长为 5 年(2018-23 年)。采用 PRISMA 方法,在六个学术数据库中进行了检索:IEEE Xplore、Dimensions、Scopus、Web of Science、PubMed 和 ACM。在应用了检索字符串和排除标准后,共确定并列出了 13 篇出版物,以构成并支持本文的讨论。所选研究根据其在医疗保健领域的应用分为两组:一组是临床应用,细分为个性化护理和生物结构再现等主题;另一组是操作应用,细分为操作流程优化、物理结构再现以及设备和药物开发等主题。在医疗保健领域使用 DT 带来了与数据整合、隐私和互操作性有关的重要挑战。然而,发展趋势表明,在个性化治疗、预防、远程监控、知情决策和流程管理等方面存在着令人振奋的潜力,可显著提高医疗保健的质量和效率。
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引用次数: 0
How is health equity considered in policy evaluations employing quasi-experimental methods? A scoping review and content analysis. 在采用准实验方法的政策评估中如何考虑健康公平问题?范围审查和内容分析。
IF 3.7 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-11-27 DOI: 10.1093/eurpub/ckae188
Kerstin Sell, Setareh Rabbani, Jacob Burns

Public health researchers employ quasi-experimental methods (QEM) to evaluate the effects of policies. Whilst some policies are designed to improve (health) equity, others may intentionally or unintentionally have detrimental effects on disadvantaged populations. We thus sought to investigate how health equity is addressed in policy evaluations which employ QEM. We conducted a content analysis on studies sourced from a scoping review. We drew a random sample of 350 records identified in systematic database searches in Medline, EMBASE, and EconLit (December 2022). Studies that employed QEM labels and examined public policies implemented in the WHO European region were included. We extracted data on study design, policies, and populations; assessed whether outcomes were examined in population sub-groups (as defined by PROGRESS-Plus criteria); and analysed discussion sections for equity-related conclusions. We included 59 studies, of which 39 (66.1%) studies considered health equity-albeit to variable depth. Twenty-five studies were focused exclusively on examining policy outcomes in a disadvantaged population (42.4%), of which 19 studies evaluated policies that targeted disadvantaged groups (e.g. minimum wage, social housing policies). Outcomes were stratified for one or more sub-populations in 22 studies (37.3%), most commonly for gender (n = 15, 25.4%) and a measure of socio-economic status (n = 13, 22%), particularly income and employment. Equity-related results and implications were discussed in 24 studies. While policy evaluations employing QEM have considerable value for informing decision-making in public health and other sectors that influence health, their potential to investigate equity impacts is currently not harnessed.

公共卫生研究人员采用准实验方法(QEM)来评估政策效果。有些政策旨在提高(健康)公平性,而有些政策则可能有意或无意地对弱势群体产生不利影响。因此,我们试图调查在采用 QEM 的政策评估中是如何处理健康公平问题的。我们对范围审查中的研究进行了内容分析。我们随机抽取了在 Medline、EMBASE 和 EconLit(2022 年 12 月)系统数据库中搜索到的 350 条记录。采用 QEM 标签并对世界卫生组织欧洲地区实施的公共政策进行审查的研究均被纳入其中。我们提取了有关研究设计、政策和人群的数据;评估了是否对人群亚组的结果进行了研究(根据 PROGRESS-Plus 标准定义);并分析了讨论部分与公平相关的结论。我们纳入了 59 项研究,其中 39 项研究(66.1%)考虑了健康公平问题,尽管考虑的深度不一。25 项研究专门针对弱势群体(42.4%)的政策结果进行了研究,其中 19 项研究评估了针对弱势群体的政策(如最低工资、社会住房政策)。有 22 项研究(37.3%)对一个或多个子人群的结果进行了分层,最常见的是性别分层(15 项,25.4%)和社会经济地位分层(13 项,22%),尤其是收入和就业分层。有 24 项研究讨论了与公平相关的结果和影响。虽然采用 QEM 的政策评估在为公共卫生和其他影响健康的部门的决策提供信息方面具有相当大的价值,但其调查公平影响的潜力目前尚未得到利用。
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引用次数: 0
Access points to different levels of health care over 13 years. Utilization behaviour in a changing health care system. Results of a three-wave cross-sectional series in Austria. 13 年间不同级别医疗服务的获取点。不断变化的医疗保健系统中的使用行为。奥地利三波横截面系列研究结果。
IF 3.7 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-11-23 DOI: 10.1093/eurpub/ckae180
Roland Kraxner, Thomas E Dorner, Dominik Roth, Kathryn Hoffmann

Providing health care is a balancing act among human resources, financial pressures and system-intrinsic factors. Understanding the utilization behaviour of primary and secondary care facilities [general practitioners (GPs) vs. specialists, as well as in- and outpatient hospital care] is crucial for a country like Austria, which has free access to all levels of care. The aim of this study was to reassess access point consultations in relation to sociodemographic variables over time. The databases used for this cross-sectional analysis were the Austrian Health Interview Surveys 2006/07, 2014, and 2019, with sample sizes of 15 474, 15 770, and 15 461 persons, respectively. Analyses included patterns of utilization behaviour, multivariable logistic regression models, and diff-in-diff analyses highlighting differences between the observation periods. GP and secondary care consultations increased from 2014 to 2019. While there were fewer GP visits in 2014 than in 2006/07, GP consultation rates grew by 3.2% between 2014 and 2019. Secondary care utilization increased by 5.4%-8.2% between 2006/07 and 2019, with the highest growth in older and less-educated persons. Secondary-level utilization without prior GP visits decreased again in 2019 after peaking in 2014. Utilization of all access points increased over the entire observation period, especially regarding secondary-level care. Higher GP visit rates do not seem to result in a drop in secondary-level consultations. These results emphasize the coordinator role of primary care in ongoing structural health reforms in European countries, such as Austria.

提供医疗服务是人力资源、财政压力和系统内在因素之间的平衡之举。对于奥地利这样一个免费提供各级医疗服务的国家来说,了解初级和二级医疗设施(全科医生与专科医生,以及医院内和门诊医疗服务)的使用行为至关重要。本研究的目的是重新评估随时间变化的社会人口变量与就诊点的关系。这项横断面分析所使用的数据库是奥地利 2006/07、2014 和 2019 年健康访谈调查,样本量分别为 15 474、15 770 和 15 461 人。分析包括利用行为模式、多变量逻辑回归模型和差异分析,以突出观察期间的差异。从 2014 年到 2019 年,全科医生和二级护理咨询有所增加。虽然 2014 年的全科医生就诊人数少于 2006/07 年,但全科医生就诊率在 2014 年至 2019 年期间增长了 3.2%。在 2006/07 年至 2019 年期间,二级医疗利用率增长了 5.4%-8.2%,其中老年人和受教育程度较低者的增长率最高。在 2014 年达到峰值后,未事先接受全科医生诊治的二级医疗利用率在 2019 年再次下降。在整个观察期内,所有就诊点的使用率都有所上升,尤其是二级医疗机构。全科医生就诊率的提高似乎并没有导致二级就诊率的下降。这些结果强调了全科医疗在奥地利等欧洲国家正在进行的结构性医疗改革中的协调作用。
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引用次数: 0
Causal association of physical activity with lymphoma risk: a Mendelian randomization analysis. 体育锻炼与淋巴瘤风险的因果关系:孟德尔随机分析。
IF 3.7 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-11-21 DOI: 10.1093/eurpub/ckae172
Jin Zhao, Xiaolian Wen, Meijing Zheng, Liping Su, Xiaojing Guo

Controversial relationship of physical activity with lower lymphoma risk has been reported in observational studies. The purpose of this study was to explore the causal correlation of physical activity with lymphoma risk using two-sample Mendelian randomization (MR). Genetic variants associated with physical activity (moderate-to-vigorous physical activity (MVPA), average acceleration physical activity, number of days/week of moderate physical activity 10+ min, and number of days/week of vigorous physical activity 10+ min) and lymphoma [overall lymphoma, Hodgkin lymphoma, mature T/NK-cell lymphomas, diffuse large B-cell lymphoma (DLBCL), and follicular lymphoma] were obtained from published genome-wide association studies (GWAS) and the FinnGen database and used as instrumental variables. Primary results were based on inverse variance-weighted (IVW) analysis and were described as odds ratio (OR) and 95% confidence interval (CI). Higher levels of genetically predicted MVPA (OR = 0.079, 95% CI: 0.021-0.300, P = 0.0002) and number of days/week of vigorous physical activity 10+ min (OR = 0.237, 95% CI: 0.098-0.573, P = 0.0014) were negatively associated with Hodgkin lymphoma risk. There was a weak negative association between high levels of genetically predicted MVPA (OR = 0.114, 95% CI: 0.015-0.856, P = 0.0348) and average acceleration physical activity (OR = 0.830, 95% CI: 0.705-0.976, P = 0.0243) and risk of DLBCL. No causal relationship was observed between physical activity and the risk of overall lymphoma, mature T/NK-cell lymphomas, and follicular lymphoma (P > 0.05). This study supported the causal relationship between higher physical activity levels and lower risks of Hodgkin lymphoma and DLBCL.

在观察性研究中,关于体育锻炼与降低淋巴瘤风险之间的关系存在争议。本研究的目的是采用双样本孟德尔随机法(MR)探讨体力活动与淋巴瘤风险的因果关系。研究人员从已发表的全基因组关联研究(GWAS)和FinnGen数据库中获取了与体力活动(中到剧烈体力活动(MVPA)、平均加速度体力活动、每周10分钟以上的中度体力活动天数和每周10分钟以上的剧烈体力活动天数)和淋巴瘤(总体淋巴瘤、霍奇金淋巴瘤、成熟T/NK细胞淋巴瘤、弥漫大B细胞淋巴瘤(DLBCL)和滤泡淋巴瘤)相关的基因变异,并将其作为工具变量。主要结果基于反方差加权(IVW)分析,并以几率比(OR)和 95% 置信区间(CI)表示。较高水平的遗传预测 MVPA(OR = 0.079,95% CI:0.021-0.300,P = 0.0002)和每周剧烈运动 10 分钟以上的天数(OR = 0.237,95% CI:0.098-0.573,P = 0.0014)与霍奇金淋巴瘤风险呈负相关。基因预测的高水平 MVPA(OR = 0.114,95% CI:0.015-0.856,P = 0.0348)和平均加速体力活动(OR = 0.830,95% CI:0.705-0.976,P = 0.0243)与 DLBCL 风险之间存在微弱的负相关。体力活动与总体淋巴瘤、成熟T/NK细胞淋巴瘤和滤泡淋巴瘤风险之间没有因果关系(P > 0.05)。这项研究支持较高的体力活动水平与较低的霍奇金淋巴瘤和 DLBCL 风险之间的因果关系。
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引用次数: 0
Public health approaches to 'Leave No One Behind' in heatwave resilience: insights from the UK. 应对热浪 "一个都不能少 "的公共卫生方法:来自英国的启示。
IF 3.7 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-11-21 DOI: 10.1093/eurpub/ckae187
Ana Raquel Nunes

Heatwaves pose significant threats to vulnerable populations, making resilience efforts crucial. This study aims to explore stakeholders' perspectives on heatwave resilience from a public health perspective, with a specific focus on operationalising the commitment to 'Leave No One Behind' (LNOB) as outlined in the United Nations 2030 Agenda for Sustainable Development. In-depth qualitative interviews were conducted with key stakeholders from national and local government, industry and business, academia, and civil society organizations. Interviews examined stakeholders' understanding of the progress and challenges associated with fulfilling the commitment of LNOB in the context of heat resilience from a public health perspective, in England, UK. Content analysis of interview transcripts was undertaken. Stakeholders emphasize the importance of equity, inclusivity, and public health priorities in heatwave resilience efforts while specifically addressing the commitment to LNOB. Disparities in vulnerability due to socioeconomic factors, challenges in identifying and supporting vulnerable populations, progress made in addressing heatwave resilience, and the role of government and society in improving resilience efforts were emphasized. Stakeholders highlighted the need for targeted interventions, strengthened community support networks, and policy changes to address systemic inequalities and promote inclusivity in resilience strategies. Stakeholders' perspectives underscore the importance of aligning heatwave resilience efforts with global goals, particularly in promoting public health equity and inclusivity. By addressing the challenges identified and implementing the recommendations for improvement, policymakers and practitioners should work towards more equitable and inclusive resilience strategies to safeguard public health during heatwaves.

热浪对弱势人群构成了重大威胁,因此抗击热浪的努力至关重要。本研究旨在从公共卫生的角度探讨利益相关者对热浪抵御能力的看法,特别关注如何落实联合国 2030 年可持续发展议程中提出的 "不让一个人掉队"(LNOB)的承诺。我们对来自国家和地方政府、工商界、学术界和民间社会组织的主要利益相关者进行了深入的定性访谈。访谈考察了利益相关者对英国英格兰从公共卫生角度出发,在抗热能力方面履行 LNOB 承诺所取得的进展和面临的挑战的理解。对访谈记录进行了内容分析。利益相关者强调了在热浪抗御工作中公平、包容和公共卫生优先事项的重要性,同时特别提到了对 LNOB 的承诺。他们还强调了社会经济因素导致的脆弱性差异、在识别和支持弱势群体方面的挑战、在应对热浪方面取得的进展以及政府和社会在提高抗击热浪能力方面的作用。利益相关者强调,需要采取有针对性的干预措施、加强社区支持网络和政策变革,以解决系统性不平等问题并促进抗灾战略的包容性。利益攸关方的观点强调了使热浪抗御工作与全球目标保持一致的重要性,特别是在促进公共卫生公平性和包容性方面。通过应对已确定的挑战和实施改进建议,决策者和从业人员应努力制定更加公平和包容的抗击热浪战略,以保障热浪期间的公众健康。
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引用次数: 0
Prevalent findings on low-dose CT scan lung cancer screening: a French prospective pilot study. 低剂量 CT 扫描肺癌筛查的普遍发现:一项法国前瞻性试点研究。
IF 3.7 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-11-20 DOI: 10.1093/eurpub/ckae183
Philippe A Grenier, Maxence Arutkin, Anne Laure Brun, Anne-Cécile Métivier, Edouard Sage, Franck Haziza, Félix Ackermann, François Mellot, Alexandre Vallée

Despite significant therapeutic advances, lung cancer remains the biggest killer among cancers. In France, there is no national screening program against lung cancer. Thus, in this perspective, the Foch Hospital decided to implement a pilot and clinical low-dose CT screening program to evaluate the efficiency of such screening. The purpose of this study was to describe the prevalent findings of this low-dose CT screening program. Participants were recruited in the screening program through general practitioners (GPs), pharmacists, and specialists from June 2023 to June 2024. The inclusion criteria included male or female participants aged 50 to 80 years, current smokers or former smokers who had quit less than 15 years prior, with a smoking history of over 20 pack-years. Chest CT scans were conducted at Foch Hospital using a low-dose CT protocol based on volume mode with a multi-slice scanner (≥60 slices) without contrast injection. In total, 477 participants were recruited in the CT scan screening, 235 (49%) were males with a median age of 60 years [56-67] and 35 smoke pack-years [29-44] and 242 females (51%) with a median age of 60 years [55-60] and 30 smoke pack-years [25-40]. Eight participants showed positive nodules on CT scan, as a 1.7% rate. 66.7% of diagnosed cancers were in early stages (0-I). It is feasible to implement structured lung cancer screening using low-dose CT in a real-world setting among the general population. This approach successfully identifies most early-stage cancers that could be treated curatively.

尽管在治疗方面取得了重大进展,但肺癌仍然是癌症中的最大杀手。法国没有全国性的肺癌筛查计划。因此,福煦医院决定实施一项低剂量 CT 筛查试点和临床项目,以评估此类筛查的效率。本研究的目的是描述该低剂量 CT 筛查项目的主要结果。2023 年 6 月至 2024 年 6 月期间,该筛查项目通过全科医生(GP)、药剂师和专科医生招募参与者。纳入标准包括 50 至 80 岁的男性或女性参与者、当前吸烟者或戒烟少于 15 年的前吸烟者、吸烟史超过 20 包年。胸部CT扫描在福煦医院进行,采用基于容积模式的低剂量CT方案,使用多层扫描仪(≥60片),不注射造影剂。共有 477 人参加了 CT 扫描筛查,其中男性 235 人(49%),中位年龄为 60 岁[56-67]和 35 个烟包年[29-44];女性 242 人(51%),中位年龄为 60 岁[55-60]和 30 个烟包年[25-40]。8 名参与者在 CT 扫描中发现了阳性结节,比例为 1.7%。66.7%的确诊癌症处于早期阶段(0-I期)。在普通人群中使用低剂量 CT 进行结构性肺癌筛查是可行的。这种方法能成功识别大多数可进行根治性治疗的早期癌症。
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引用次数: 0
Lessons learned from Taiwan's response to the COVID-19 pandemic: successes, challenges, and implications for future pandemics. 台湾应对 COVID-19 大流行的经验教训:成功、挑战和对未来大流行的影响。
IF 3.7 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-11-20 DOI: 10.1093/eurpub/ckae185
Vivian Chia-Rong Hsieh, Min-Hua Tsai, Hua-Chueh Chiang, Ming-Yi Weng

This study aims to provide an investigation of the containment and mitigation strategies encompassing the entirety of the pandemic in Taiwan. This descriptive, observational study used COVID-19 data from Taiwan, Japan, and South Korea, and analysed news releases from the Taiwanese health authority. Statistics provided evidence of outbreak severity through infection and mortality rates, while qualitative results from the document review offered insights on the actions taken by the government chronologically from 2 February 2020 to 31 December 2022. All three countries experienced significant infection peaks in 2022. Taiwan had two distinct peaks, one in late May and another in October. South Korea had a single, high peak in late March, while Japan experienced multiple smaller waves, the biggest wave in August. Similarly, weekly mortality rates peaked in 2022 for all three countries after a surge in their infected cases, with Taiwan (5.15/100 000) and South Korea (4.69/100 000) having higher rates than Japan (1.65/100 000). Results from qualitative analysis showed that Taiwan's early containment measures might have delayed the epidemic curve, allowing time for better preparation and proactive responses. However, the lack of a clear transition plan and the vulnerability of the elderly population contributed to higher mortality and infection rates. Despite ongoing challenges, Taiwan avoided nationwide lockdowns and relied on targeted restrictions to control transmission of the virus. Results of this article offer the narratives, reflections, and experiences from the case of Taiwan which may potentially present promising opportunities for impact in other settings and for future pandemics.

本研究旨在调查台湾在整个大流行期间的遏制和缓解策略。这项描述性观察研究使用了来自台湾、日本和韩国的 COVID-19 数据,并分析了台湾卫生当局发布的新闻。统计数据通过感染率和死亡率提供了疫情严重程度的证据,而文件审查的定性结果则提供了有关政府从 2020 年 2 月 2 日至 2022 年 12 月 31 日按时间顺序所采取的行动的见解。这三个国家在 2022 年都出现了明显的感染高峰。台湾有两个明显的高峰,一个在 5 月底,另一个在 10 月。韩国在 3 月下旬出现了一次较高的高峰,而日本则经历了多次较小的波峰,最大的波峰出现在 8 月。同样,在感染病例激增之后,这三个国家的周死亡率都在 2022 年达到峰值,其中台湾(5.15/100000)和韩国(4.69/100000)的死亡率高于日本(1.65/100000)。定性分析的结果表明,台湾的早期遏制措施可能延缓了疫情曲线,使人们有时间做出更好的准备和积极的应对。然而,由于缺乏明确的过渡计划以及老年人群的脆弱性,导致了较高的死亡率和感染率。尽管面临持续的挑战,台湾还是避免了全国范围的封锁,而是依靠有针对性的限制措施来控制病毒的传播。这篇文章的结果提供了台湾案例的叙述、反思和经验,这可能为在其他环境和未来的大流行病中产生影响提供了有希望的机会。
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