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Reducing Human Error in Global Healthcare: Leadership, Learning, and System Resilience. 减少全球医疗保健中的人为错误:领导力、学习和系统弹性。
IF 3.9 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-03-19 DOI: 10.1093/eurpub/ckag053
Ayza Altaf, Enemona Jacob
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引用次数: 0
Health's influence on alcohol use-a longitudinal study of working adults in Sweden. 健康对饮酒的影响——一项对瑞典在职成年人的纵向研究。
IF 3.9 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-03-14 DOI: 10.1093/eurpub/ckag037
Erica Jonsson, Devy L Elling, Jonas Landberg, Magnus Helgesson, Andreas Lundin, Emelie Thern

While alcohol's health effects are well documented, less is known about how health influences alcohol use and whether this varies by socioeconomic position (SEP). This study investigated the association between health-related quality of life (HRQoL), mental health, and alcohol use, and whether SEP moderates these associations. Baseline data from 7097 participants in the 2010 Stockholm Public Health Cohort were used. The exposures were HRQoL and mental health (good, moderate, poor); Outcomes (2014) were heavy episodic drinking (HED: ≥5 units/≥2 times/month) and heavy drinking (men: ≥21 units/week; women: ≥14 units/week). Logistic regression estimated odds ratios (OR), with interaction assessed using relative excess risk of interaction (RERI) and attributable proportion (AP). Joint exposure analyses used good health and high SEP as the reference group. Compared with good HRQoL, moderate (OR: 1.26, 95% CI: 1.02-1.56) and poor HRQoL (OR: 1.39, 95% CI: 1.08-1.78) were associated with higher odds of heavy drinking. Moderate HRQoL and low SEP had increased odds of HED (OR: 1.48, 95% CI: 1.02-2.15) and heavy drinking (OR: 1.62, 95% CI: 1.01-2.60), with evidence of additive interaction (RERI: 0.79; AP: 0.49). Mental health findings were less consistent: good mental health and low SEP was associated with increased HED (OR: 1.35), while moderate mental health and intermediate SEP was associated with decreased HED (OR: 0.66). Findings suggest a dose-response relationship between HRQoL and self-reported heavy drinking and an interaction between moderate HRQoL and low SEP. Associations with mental health were weaker and inconsistent.

虽然酒精对健康的影响有充分的记录,但人们对健康如何影响饮酒以及这是否因社会经济地位(SEP)而异所知甚少。本研究调查了健康相关生活质量(HRQoL)、心理健康和酒精使用之间的关系,以及SEP是否调节了这些关系。使用了2010年斯德哥尔摩公共卫生队列中7097名参与者的基线数据。暴露为HRQoL和心理健康(好、中、差);结果(2014年)是重度间歇性饮酒(HED:≥5单位/≥2次/月)和重度饮酒(男性:≥21单位/周;女性:≥14单位/周)。Logistic回归估计优势比(OR),使用相对过度相互作用风险(rei)和归因比例(AP)评估相互作用。联合暴露分析以健康和高SEP为参照组。与良好的HRQoL相比,中度(OR: 1.26, 95% CI: 1.02-1.56)和较差的HRQoL (OR: 1.39, 95% CI: 1.08-1.78)与大量饮酒的几率较高相关。中度HRQoL和低SEP增加了HED (OR: 1.48, 95% CI: 1.02-2.15)和重度饮酒(OR: 1.62, 95% CI: 1.01-2.60)的几率,并有证据表明存在加性相互作用(rei: 0.79; AP: 0.49)。心理健康调查结果不太一致:良好的心理健康和低SEP与HED增加相关(OR: 1.35),而中度心理健康和中等SEP与降低HED相关(OR: 0.66)。研究结果表明,HRQoL与自我报告的重度饮酒之间存在剂量反应关系,中度HRQoL与低SEP之间存在相互作用,与心理健康的关联较弱且不一致。
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引用次数: 0
Assessing the return-to-work mode of precarious workers with mental health issues: reliability, validity, and usability of the REMODE-tool. 评估有心理健康问题的不稳定工人重返工作模式:remode工具的可靠性、有效性和可用性
IF 3.9 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-03-14 DOI: 10.1093/eurpub/ckag014
Yvonne B Suijkerbuijk, Frederieke G Schaafsma, Lyanne P Jansen, Karen Nieuwenhuijsen

Mental health issues are highly prevalent among precarious workers, often leading to prolonged sickness absence and unemployment. A worker's perceptions and attitudes about return-to-work are important determinants of work resumption and can be categorized into three modes: an expectant, an ambivalent-uncertain, and an active return-to-work mode. To support professionals in identifying these modes, we developed the REturn-to-work MODe Evaluation (REMODE) tool. This study evaluated REMODE's inter-rater agreement, inter-item consistency, content validity, and usability. In a vignette study, 71 occupational health professionals from a Dutch social security institute viewed six videos of consultations between insurance physicians and precarious workers. They then used REMODE to assess the worker's return-to-work mode and need for occupational support. Participants also rated REMODE's validity and usability with 5-point Likert scale questions based on the Content Validity Index and System Usability Scale. We used a generalized linear mixed model to analyse inter-rater agreement and inter-item consistency. The professionals highly agreed on the REMODE-score [ICC 0.87 (95% CI 0.63-0.97)] and corresponding return-to-work mode [ICC 0.83 (0.54-0.95), Κω 0.75 (0.74-0.75)]. Their agreement on need for occupational support was moderate [ICC 0.65 (0.30-0.89), Κω 0.57 (0.56-0.57)]. REMODE's internal consistency demonstrated excellence (Cronbach's alpha 0.92), and the content validity index (0.83) and system usability scale (76) were acceptable. REMODE is a promising tool for occupational health professionals as it supports identification of the return-to-work mode of precarious workers with mental health issues. We propose a refined version of RE-MODE for use in occupational healthcare and research.

精神健康问题在不稳定的工人中非常普遍,往往导致长期病假和失业。工人对重返工作岗位的看法和态度是恢复工作的重要决定因素,可分为三种模式:期待,矛盾-不确定和积极重返工作岗位模式。为了支持专业人员识别这些模式,我们开发了回归工作模式评估(REMODE)工具。本研究评估REMODE的评分者间一致性、项目间一致性、内容效度和可用性。在一项小短片研究中,来自荷兰社会保障机构的71名职业健康专家观看了6段关于保险医生和不稳定工人之间咨询的视频。然后,他们使用REMODE来评估工人重返工作模式和对职业支持的需求。参与者还根据内容有效性指数和系统可用性量表用5分李克特量表对REMODE的有效性和可用性进行了评分。我们使用广义线性混合模型来分析评分者之间的一致性和项目之间的一致性。专业人员高度认同remode得分[ICC 0.87 (95% CI 0.63-0.97)]和相应的重返工作模式[ICC 0.83 (0.54-0.95), Κω 0.75(0.74-0.75)]。他们对职业支持需求的一致性是中等[ICC 0.65 (0.30-0.89), Κω 0.57(0.56-0.57)]。REMODE的内部一致性表现优异(Cronbach's alpha 0.92),内容效度指数(0.83)和系统可用性量表(76)可接受。REMODE对于职业卫生专业人员来说是一个很有前途的工具,因为它有助于确定有精神健康问题的不稳定工人的重返工作模式。我们提出了一个改进版本的RE-MODE用于职业保健和研究。
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引用次数: 0
Trends in cost-related forgone care among older adults in Switzerland: a repeated cross-sectional study. 瑞士老年人中与费用相关的放弃护理的趋势:一项重复的横断面研究。
IF 3.9 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-03-14 DOI: 10.1093/eurpub/ckag010
Mathieu Jendly, Stéphane Cullati, Cornelia Wagner, Axelle Braggion, Valérie Santschi, Arnaud Chiolero

Background: Ensuring equitable healthcare provision is key in ageing societies, yet it may be hindered by financial barriers. We assessed trends and socioeconomic disparities in cost-related forgone medical care among Swiss adults aged 65 years and older between 2017 and 2024.

Methods: We used data from the 2017, 2021, and 2024 waves of the 'International Health Policy Survey', a population-based study of randomly sampled adults aged 65 or older (n = 2570, 1888, and 1948, respectively). Participants reported whether they had forgone medical prescriptions, consultations, medical tests, treatments or follow-up consultations, and dental visits due to cost. Weighted prevalence estimates were computed for services covered by the basic insurance and for dental care. Disparities by education and income were assessed using stratified analyses and the index of disparity.

Results: Participants' characteristics were stable across all waves (mean age 75; 54% women). In 2024, 20% reported forgoing at least one service due to cost (13% forgoing dental care, 13% insurance-covered services). Forgone care was similar in 2017 (21%) and lower in 2021 (16%). Forgone care was more frequent among men and participants aged 65-79 years. The index of disparity showed widening income-related disparities over time, while disparities by education remained stable. Dental care consistently showed the largest disparities.

Conclusion: Despite Switzerland's compulsory health insurance, one in five older adults still forgo care for financial reasons. Rates of forgone care remained stable, but income disparities have widened since 2017.

背景:确保公平的医疗保健提供是老龄化社会的关键,但它可能受到财政障碍的阻碍。我们评估了2017年至2024年间瑞士65岁及以上成年人中与费用相关的放弃医疗服务的趋势和社会经济差异。方法:我们使用了2017年、2021年和2024年“国际卫生政策调查”的数据,这是一项基于人群的研究,随机抽样65岁及以上的成年人(n = 2570、1888和1948)。参与者报告了他们是否因费用原因放弃了医疗处方、咨询、医疗检查、治疗或后续咨询以及牙科就诊。对基本保险所涵盖的服务和牙科保健的加权患病率估计进行了计算。通过分层分析和差异指数来评估教育和收入的差异。结果:参与者的特征在所有波中都是稳定的(平均年龄75岁;54%是女性)。2024年,20%的受访者表示,由于成本原因,他们至少放弃了一项服务(13%放弃了牙科护理,13%放弃了保险覆盖的服务)。2017年放弃护理的比例相似(21%),2021年更低(16%)。放弃护理在65-79岁的男性和参与者中更为常见。差距指数显示,随着时间的推移,与收入相关的差距越来越大,而教育方面的差距则保持稳定。牙科保健一直显示出最大的差距。结论:尽管瑞士实行强制性医疗保险,但仍有五分之一的老年人出于经济原因放弃医疗。放弃医疗的比例保持稳定,但自2017年以来,收入差距扩大了。
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引用次数: 0
Allergy prevention-a new public health perspective. 预防过敏——一个新的公共卫生视角。
IF 3.9 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-03-14 DOI: 10.1093/eurpub/ckaf258
Tari Haahtela, Pekka Puska
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引用次数: 0
Commercial determinants of health-a scoping review of research 'made in Germany'. 健康的商业决定因素——对“德国制造”研究的范围审查。
IF 3.9 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-03-14 DOI: 10.1093/eurpub/ckag030
Kerstin Sell, Stefanie Nigg, Anna Leibinger, Stephan Voss, Carmen Klinger, Eva Rehfuess

Commercial products such as tobacco, alcohol, ultra-processed food and fossil fuels drive the global burden of non-communicable diseases (NCDs) and the escalating climate crisis. The concept 'commercial determinants of health' (CDOH) offers a framework for understanding the ways in which commercial actors, processes, and products influence health. With most CDOH research originating from Anglo-Saxon countries, we sought to map Germany's CDOH research landscape and related scientific discourse. We conducted a scoping review according to a pre-registered protocol. Records were identified through systematic searches in Medline, Embase, Web of Science, and Google Scholar, last updated 6 December 2024, and by searching seminal CDOH literature. We included peer-reviewed articles (co-)authored by researchers affiliated with German institutions, which examined the public health effects of corporate sector practices; results were presented in an evidence map. We included 136 articles, comprising 64 original research articles (47.1%), 36 overview type articles (26.5%), and 17 opinion pieces (12.5%). Fifteen mentioned the 'commercial determinants of health' (11.0%). Research activities focused on the tobacco, alcohol, food, and pharmaceutical industries; articles were primarily concerned with political, scientific, marketing, and reputational management practices. A supplementary social network analysis showed fragmented authorship networks. CDOH are key upstream determinants to consider in the prevention of NCDs. Germany faces a substantial and growing burden of disease from NCDs but the country's research on the CDOH is limited. We suggest that researchers embrace the scholarship on CDOH, and that practitioners harness relevant insights in addressing the commercially driven NCD burden.

烟草、酒精、超加工食品和化石燃料等商业产品加剧了全球非传染性疾病负担和不断升级的气候危机。“健康的商业决定因素”(CDOH)概念为理解商业行为者、过程和产品影响健康的方式提供了一个框架。由于大多数CDOH研究起源于盎格鲁-撒克逊国家,我们试图绘制德国的CDOH研究景观和相关的科学话语。我们根据预先注册的协议进行了范围审查。通过系统检索Medline、Embase、Web of Science和谷歌Scholar(最后更新日期为2024年12月6日)以及检索具有开创性的CDOH文献来确定记录。我们纳入了由隶属于德国机构的研究人员共同撰写的同行评议文章,这些文章研究了企业部门的做法对公共卫生的影响;结果以证据图的形式呈现。我们纳入了136篇文章,包括64篇原创研究文章(47.1%),36篇综述型文章(26.5%)和17篇评论文章(12.5%)。15个国家提到了“健康的商业决定因素”(11.0%)。以烟草、酒精、食品和制药工业为重点的研究活动;文章主要关注政治、科学、市场营销和声誉管理实践。一项补充的社会网络分析显示,作者网络是碎片化的。CDOH是预防非传染性疾病中需要考虑的关键上游决定因素。德国面临着来自非传染性疾病的巨大且日益增长的疾病负担,但该国对CDOH的研究有限。我们建议研究人员接受CDOH方面的学术研究,并建议从业人员利用相关见解来解决商业驱动的非传染性疾病负担。
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引用次数: 0
Evaluating cross-country applicability of morbidity scores: validation of the Multisource Comorbidity Score in Catalonia. 评估发病率评分的跨国适用性:加泰罗尼亚多源合并症评分的验证。
IF 3.9 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-03-14 DOI: 10.1093/eurpub/ckag022
Alessandro Fontanarosa, Flavia Carle, Roberta Papa, Marco Pompili, Giovanni Corrao, Damià Valero-Bover, Josep Roca, Rubèn González-Colom, Edlira Skrami

Multimorbidity places increasing pressure on healthcare systems, requiring effective tools to assess clinical complexity. Existing comorbidity indices are often setting-specific and lack generalizability. The Multisource Comorbidity Score (MCS), developed in Italy, has shown strong predictive value. This study aimed to externally validate MCS and to test recalibrated and context-adapted versions to enhance its performance in a different healthcare system. A longitudinal observational study included 198 753 residents aged ≥50 in the Barcelona-Esquerra health district, followed between 2016 and 2019. The original MCS was validated, and two adapted versions were tested: a recalibrated MCS with locally derived weights and an enhanced MCS incorporating primary care data. Predictive validity for 1-year mortality (primary outcome) and secondary outcomes (4-year mortality, hospitalizations, and healthcare use) was assessed using the Area Under the Receiver Operating Characteristic (AUROC) curve, survival analysis, and net reclassification improvement (NRI). All MCS versions showed good discrimination. AUROCs for 1-year mortality were 0.742 (original), 0.756 (recalibrated), and 0.771 (enhanced). Adapted versions achieved better risk reclassification and higher discrimination for long-term mortality. Higher MCS scores were associated with progressively lower survival probabilities and increased healthcare resource utilization. The MCS demonstrated satisfactory external validity in the validation context, with adapted versions offering modest improvements.

多病给医疗保健系统带来越来越大的压力,需要有效的工具来评估临床复杂性。现有的合并症指标往往是特定的,缺乏普遍性。意大利开发的多源共病评分(MCS)显示出很强的预测价值。本研究旨在从外部验证MCS,并测试重新校准和适应环境的版本,以提高其在不同医疗保健系统中的性能。一项纵向观察研究包括巴塞罗那-埃斯奎拉卫生区年龄≥50岁的198753名居民,随访时间为2016年至2019年。验证了原始的MCS,并测试了两个改编版本:一个重新校准的MCS与本地导出的权重和一个增强的MCS纳入初级保健数据。采用受试者工作特征(AUROC)曲线下面积、生存分析和净再分类改善(NRI)评估1年死亡率(主要结局)和次要结局(4年死亡率、住院和医疗使用)的预测效度。所有MCS版本都表现出良好的辨别能力。1年死亡率的auroc分别为0.742(原始)、0.756(重新校准)和0.771(增强)。改编版本在长期死亡率方面实现了更好的风险重新分类和更高的歧视。较高的MCS评分与逐渐降低的生存概率和增加的医疗资源利用率相关。MCS在验证环境中表现出令人满意的外部效度,改编版本提供了适度的改进。
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引用次数: 0
Towards the institutionalization of wastewater surveillance for public health: results from the EU-WISH mapping survey. 为促进公共卫生将废水监测制度化:欧盟-世界卫生组织测绘调查的结果。
IF 3.9 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-03-14 DOI: 10.1093/eurpub/ckaf259
Jose Antonio Baz-Lomba, Jori Perälä, Tarja Pitkänen, Tuija Leino

Wastewater-based surveillance (WBS) is increasingly recognized as a valuable tool for monitoring public health at the population level. However, its integration into national public health frameworks across Europe remains uneven. In mid-2024, the EU-WISH Joint Action conducted a system mapping survey across 27 European countries to assess the governance, development, and integration of WBS systems. The survey combined quantitative and qualitative data to evaluate national strategies, legal and financial frameworks, and system capacities. By May 2024, most participating countries had operational WBS systems, primarily targeting SARS-CoV-2. Other monitored targets included influenza and other respiratory viruses, poliovirus, antimicrobial resistance (AMR), emerging pathogens, illicit drugs, and health-related biomarkers. Prioritization in system design was largely based on operational feasibility and perceived public health value. Challenges identified included fragmented governance, lack of sustainable financing, and limited workforce capacity. Integration into public health decision-making varied, and dissemination practices differed significantly across countries and surveillance targets. The EU-WISH survey provides a baseline assessment of WBS implementation across Europe and highlights key enablers and barriers to its institutionalization. The findings support ongoing efforts at national and EU levels to enhance coordination, sustainability, and integration of WBS into routine public health frameworks.

基于废水的监测(WBS)越来越被认为是监测人口层面公共卫生的宝贵工具。然而,欧洲各国将其纳入国家公共卫生框架的情况仍然参差不齐。2024年中期,EU-WISH联合行动在27个欧洲国家进行了系统测绘调查,以评估WBS系统的治理、发展和集成。该调查结合了定量和定性数据,以评估国家战略、法律和财务框架以及系统能力。到2024年5月,大多数参与国都拥有可操作的WBS系统,主要针对SARS-CoV-2。其他监测目标包括流感和其他呼吸道病毒、脊髓灰质炎病毒、抗菌素耐药性(AMR)、新出现的病原体、非法药物和与健康有关的生物标志物。系统设计的优先次序主要基于操作可行性和感知到的公共卫生价值。确定的挑战包括治理分散、缺乏可持续融资和劳动力能力有限。纳入公共卫生决策的情况各不相同,传播做法在不同国家和监测目标之间存在显著差异。EU-WISH调查提供了整个欧洲实施WBS的基线评估,并突出了其制度化的关键推动因素和障碍。研究结果支持国家和欧盟层面正在进行的努力,以加强协调、可持续性,并将WBS纳入常规公共卫生框架。
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引用次数: 0
Assessing all-cause mortality and years of life lost associated with impaired biological health over time: the Tromsø study. 评估与生物健康受损相关的全因死亡率和寿命损失年数:特罗姆瑟研究。
IF 3.9 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-03-14 DOI: 10.1093/eurpub/ckag005
Lola Neufcourt, Cyrille Delpierre, Michelle Kelly-Irving, Erlend H Farbu, Tom Wilsgaard, Sameline Grimsgaard, David Tang, Dragana Vuckovic, Marc Chadeau-Hyam, Torkjel M Sandanger, Raphaële Castagné

Prior research has shown that high composite biological health scores (BHS, based on the allostatic load theory of multisystem physiological dysregulation) are associated with mortality. However, most of this work remains cross-sectional and does not explore the implications of long-term biological health changes, although this is an essential perspective for a better understanding of ageing and health span. To explore the relationship between BHS-at two time points and longitudinally-and mortality, we analysed waves six (2007-08) and seven (2015-16) of the Tromsø Study linked with all-cause mortality data from the Norwegian Population Registry up to 2022. Using 10 biomarkers from 8117 individuals, we created 2-category (low/high) Tromsø6-BHS, Tromsø7-BHS, and longitudinal BHS measures. Cox proportional hazard regression analysis adjusted for confounders revealed that both higher Tromsø6-BHS and Tromsø7-BHS were significant predictors of mortality 15 and 7 years later, respectively (Tromsø6-BHS: HR = 1.20 [0.99-1.45]; Tromsø7-BHS: HR = 1.26 [1.05-1.52]), and that the 7-year mortality risk was more pronounced for the longitudinal BHS (1.30 [1.09-1.56]). Corresponding sex- and age-adjusted median survival was lowered by 0.71, 1.69, and 1.84 years in participants with a high versus low Tromsø6-BHS, Tromsø7-BHS and longitudinal-BHS, respectively. These results indicate that both historical elevations of BHS and their cumulation over time play a role in determining mortality risk. Our findings underline the importance of monitoring biological health over the life course as a preventive measure and suggest that individuals with high BHS levels may benefit from dynamic monitoring from mid-adulthood to mitigate the risk of premature mortality.

先前的研究表明,高复合生物健康评分(BHS,基于多系统生理失调的适应负荷理论)与死亡率相关。然而,尽管这是更好地理解老龄化和健康跨度的一个重要视角,但大多数这项工作仍然是横向的,没有探索长期生物健康变化的影响。为了探索两个时间点的bhs和纵向与死亡率之间的关系,我们分析了特罗姆瑟研究的第6波(2007-08)和第7波(2015-16)与挪威人口登记处截至2022年的全因死亡率数据相关。使用来自8117个人的10种生物标志物,我们创建了2类(低/高)Tromsø6-BHS、Tromsø7-BHS和纵向BHS测量。校正混杂因素的Cox比例风险回归分析显示,较高的Tromsø6-BHS和Tromsø7-BHS分别是15年和7年后死亡率的显著预测因子(Tromsø6-BHS: HR = 1.20 [0.99-1.45]; Tromsø7-BHS: HR = 1.26[1.05-1.52]),且纵向BHS的7年死亡率风险更为显著(1.30[1.09-1.56])。在Tromsø6-BHS、Tromsø7-BHS和纵向bhs高与低的受试者中,相应的性别和年龄调整后的中位生存期分别降低了0.71年、1.69年和1.84年。这些结果表明,BHS的历史升高及其随时间的累积在确定死亡风险方面发挥了作用。我们的研究结果强调了在整个生命过程中监测生物健康作为一种预防措施的重要性,并建议BHS水平高的个体可能从成年中期开始进行动态监测,以减轻过早死亡的风险。
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引用次数: 0
Social support and hospitalization in the elderly: investigating the role of frailty trajectories. 老年人的社会支持和住院:调查脆弱轨迹的作用。
IF 3.9 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-03-14 DOI: 10.1093/eurpub/ckag011
Paola Scarcella, Fausto Ciccacci, Annamaria Doro Altan, Olga Madaro, Leonardo Emberti Gialloreti, Stefano Orlando, Clara Donnoli, Michele Bisogno, Fabio Riccardi, Rita Cutini, Giuseppe Liotta

Biopsychosocial frailty, integrating physical, psychological, and social dimensions, significantly affects health outcomes in older adults. Hospitalization, a major contributor to healthcare burden, is strongly associated with frailty. However, the role of socioeconomic determinants within frailty trajectories remains insufficiently explored. This study aimed to evaluate the association between biopsychosocial frailty trajectories and hospitalization rates, with a focus on social determinants. We conducted a retrospective cohort study involving 6086 individuals (mean age 83.6 ± 4.9 years; 65.9% women). They underwent serial frailty assessments between 2016 and 2024 using the Short Functional Geriatric Evaluation (SFGE). Frailty trajectories were categorized as improved, stable, or worsened. Hospitalization rates were analyzed through parametric/non-parametric tests and negative binomial regression models adjusted for age, baseline frailty, and psycho-physical status. Hospitalization rates increased with frailty severity: 84‰ in robust, 97‰ in pre-frail, 149‰ in frail, and 136‰ in very frail individuals (P < 0.001). Improved or stable financial conditions significantly reduced hospitalization risk (rate ratio [RR] 0.24 and 0.41, respectively), as did stable or restored informal support networks (RR 0.45 and 0.79, respectively). Improved living arrangements were also associated with reduced hospital admissions. Robust and pre-frail individuals accounted for ∼50% of all admissions. Social and economic stability are key protective factors against hospitalization in older adults, independent of physical frailty. Community-based interventions addressing social isolation and financial vulnerability could substantially reduce hospital admissions, particularly among robust and pre-frail individuals. A holistic approach integrating social, economic, and physical frailty dimensions is recommended to optimize public health strategies for aging populations.

生理、心理和社会脆弱综合了身体、心理和社会维度,显著影响老年人的健康结果。住院治疗是医疗负担的主要来源,与身体虚弱密切相关。然而,社会经济决定因素在脆弱性轨迹中的作用仍未得到充分探讨。本研究旨在评估生物心理社会脆弱性轨迹与住院率之间的关系,重点关注社会决定因素。我们进行了一项回顾性队列研究,涉及6086名个体(平均年龄83.6 ± 4.9 岁,女性占65.9%)。他们在2016年至2024年期间使用短功能老年评估(SFGE)进行了一系列虚弱评估。虚弱的轨迹被分类为改善、稳定或恶化。通过参数/非参数检验和负二项回归模型分析住院率,调整年龄、基线虚弱和心理-身体状态。住院率随虚弱严重程度的增加而增加:强壮者84‰,体弱前期97‰,体弱者149‰,非常体弱者136‰
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European Journal of Public Health
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