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Neutrophil-to-lymphocyte Ratio as an Effective Biomarker for Meningioma: A Systematic Review and Meta-analysis 作为脑膜瘤有效生物标志物的中性粒细胞与淋巴细胞比率：系统回顾和元分析
Exploratory Research and Hypothesis in Medicine
Pub Date : 2023-12-08 DOI: 10.14218/erhm.2023.00068
Shokoufeh Khanzadeh, Amir Azarhomayoun, Rahem Rahmati, Fatemeh Zari Meidani, Caroline Baughn, Alec Clark, Mehrnoosh Ebadi, Monireh Khanzadeh, B. Lucke-Wold, Arshin Ghaedi
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引用次数: 0
Cancers Associated with Human Papillomavirus: An Overview of Prevalence in Iran and the Middle East 与人类乳头瘤病毒有关的癌症：伊朗和中东地区发病率概览
Exploratory Research and Hypothesis in Medicine
Pub Date : 2023-11-29 DOI: 10.14218/erhm.2023.00053
H. B. Baghi, Parisa Shiri Aghbash, Reyhane Rasizadeh, V. Poortahmasebi, Farbod Alinezhad
© 2023 The Author(s). This article has been published under the terms of Creative Commons Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0), which permits noncommercial unrestricted use, distribution, and reproduction in any medium, provided that the following statement is provided. “This article has been published in Exploratory Research and Hypothesis in Medicine at https://doi.org/10.14218/ERHM.2023.00053 and can also be viewed on the Journal’s website at https://www.xiahepublishing.com/journal/erhm ”.
© 2023 作者。本文根据知识共享署名-非商业性 4.0 国际许可协议（CC BY-NC 4.0）发布，该协议允许在任何媒体上进行非商业性的无限制使用、传播和复制，但必须提供以下声明。"本文已发表在《医学中的探索性研究与假设》（Exploratory Research and Hypothesis in Medicine）上，网址为 https://doi.org/10.14218/ERHM.2023.00053，也可在该期刊网站 https://www.xiahepublishing.com/journal/erhm 上查阅"。
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引用次数: 0
Trends and Outcomes of Twin Births in Southwest Nigeria: A 14-Year Retrospective Cohort Study 尼日利亚西南部双胞胎出生的趋势和结果：14 年回顾性队列研究
Exploratory Research and Hypothesis in Medicine
Pub Date : 2023-11-29 DOI: 10.14218/erhm.2023.00039
E. Igbodike, O. Ijarotimi, A. Ubom, G. Eleje, Chigbo Chisom God’swill, B. Okpala, N. Nwaogu, K. Ajenifuja, J. Ikechebelu, O. Loto, Uche Onwudiegwu, A. Eke
{"title":"Trends and Outcomes of Twin Births in Southwest Nigeria: A 14-Year Retrospective Cohort Study","authors":"E. Igbodike, O. Ijarotimi, A. Ubom, G. Eleje, Chigbo Chisom God’swill, B. Okpala, N. Nwaogu, K. Ajenifuja, J. Ikechebelu, O. Loto, Uche Onwudiegwu, A. Eke","doi":"10.14218/erhm.2023.00039","DOIUrl":"https://doi.org/10.14218/erhm.2023.00039","url":null,"abstract":"","PeriodicalId":12074,"journal":{"name":"Exploratory Research and Hypothesis in Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139213653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ophiocordyceps sinensis: A Potential Caterpillar Fungus 
for the Production of Bioactive Compounds 中华麦角菌：一种生产生物活性化合物的潜在毛孢真菌
Exploratory Research and Hypothesis in Medicine
Pub Date : 2023-11-17 DOI: 10.14218/erhm.2023.00040
Paulchamy Chellapandi, Shanmugam Saranya
{"title":"Ophiocordyceps sinensis: A Potential Caterpillar Fungus \u2028for the Production of Bioactive Compounds","authors":"Paulchamy Chellapandi, Shanmugam Saranya","doi":"10.14218/erhm.2023.00040","DOIUrl":"https://doi.org/10.14218/erhm.2023.00040","url":null,"abstract":"","PeriodicalId":12074,"journal":{"name":"Exploratory Research and Hypothesis in Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139264683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of a New Noninvasive Jos CVD Risk App and ASCVD Estimator Plus App for Prediction of Atherosclerotic Cardiovascular Disease (ASCVD) Risk in Sub-Saharan African Adult Populations 比较新型无创 Jos CVD 风险应用程序和 ASCVD Estimator Plus 应用程序，预测撒哈拉以南非洲成人的动脉粥样硬化性心血管疾病 (ASCVD) 风险
Exploratory Research and Hypothesis in Medicine
Pub Date : 2023-11-17 DOI: 10.14218/erhm.2023.00041
Anil I. Sirisena, Gabriel Z. Shut, Basil N. Okeahialam, Nentawe Gurumdimma, David E. Oguche
{"title":"Comparison of a New Noninvasive Jos CVD Risk App and ASCVD Estimator Plus App for Prediction of Atherosclerotic Cardiovascular Disease (ASCVD) Risk in Sub-Saharan African Adult Populations","authors":"Anil I. Sirisena, Gabriel Z. Shut, Basil N. Okeahialam, Nentawe Gurumdimma, David E. Oguche","doi":"10.14218/erhm.2023.00041","DOIUrl":"https://doi.org/10.14218/erhm.2023.00041","url":null,"abstract":"","PeriodicalId":12074,"journal":{"name":"Exploratory Research and Hypothesis in Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139265257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Delivery Systems Using Glycyrrhizic Acid for Allergen-specific Immunotherapy 将甘草酸用于过敏原特异性免疫疗法的给药系统
Exploratory Research and Hypothesis in Medicine
Pub Date : 2023-11-17 DOI: 10.14218/erhm.2023.00063
E. Pashkina, Maria Bykova, Olga Krugleeva, Vladimir Kozlov
© 2023 The Author(s). This article has been published under the terms of Creative Commons Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0), which permits noncommercial unrestricted use, distribution, and reproduction in any medium, provided that the following statement is provided. “This article has been published in Exploratory Research and Hypothesis in Medicine at https://doi.org/10.14218/ERHM.2023.00063 and can also be viewed on the Journal’s website at https://www.xiahepublishing.com/journal/erhm ”.
© 2023 作者。本文根据知识共享署名-非商业性 4.0 国际许可协议（CC BY-NC 4.0）发布，该协议允许在任何媒体上进行非商业性的无限制使用、传播和复制，但必须提供以下声明。"本文已发表在《医学中的探索性研究与假设》（Exploratory Research and Hypothesis in Medicine）上，网址为 https://doi.org/10.14218/ERHM.2023.00063，也可在该期刊网站 https://www.xiahepublishing.com/journal/erhm 上查阅"。
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引用次数: 0
Respiratory Patterns in Neurological Injury, Pathophysiology, Ventilation Management, and Future Innovations: A Systematic Review. 神经损伤的呼吸模式、病理生理学、通气管理和未来创新：系统回顾。
Exploratory Research and Hypothesis in Medicine
Pub Date : 2023-10-01 Epub Date: 2022-09-28 DOI: 10.14218/erhm.2022.00081
Matthew Goldman, Brandon Lucke-Wold, Jason Katz, Bavly Dawoud, Abeer Dagra

Traumatic brain injuries (TBI), ischemic stroke, hemorrhagic stroke, brain tumors, and seizures have diverse and sometimes overlapping associated breathing patterns. Homeostatic mechanisms for respiratory control are intertwined with complex neurocircuitry, both centrally and peripherally. This paper summarizes the neurorespiratory control and pathophysiology of its disruption. It also reviews the clinical presentation, ventilatory management, and emerging therapeutics. This review additionally serves to update all recent preclinical and clinical research regarding the spectrum of respiratory dysfunction. Having a solid pathophysiological foundation of disruptive mechanisms would permit further therapeutic development. This novel review bridges experimental/physiological data with bedside management, thus allowing neurosurgeons and intensivists alike to rapidly diagnose and treat respiratory sequelae of acute brain injury.

创伤性脑损伤（TBI）、缺血性中风、出血性中风、脑肿瘤和癫痫发作的相关呼吸模式多种多样，有时甚至相互重叠。呼吸控制的平衡机制与复杂的中枢和外周神经回路相互交织。本文概述了神经呼吸控制及其紊乱的病理生理学。它还回顾了临床表现、通气管理和新兴疗法。此外，本综述还介绍了有关呼吸功能障碍的所有最新临床前和临床研究。有了破坏机制的坚实病理生理学基础，才能进一步开发治疗方法。这篇新颖的综述将实验/生理学数据与床边管理联系起来，从而使神经外科医生和重症监护医生都能快速诊断和治疗急性脑损伤的呼吸系统后遗症。
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引用次数: 0
Efficacy of COVID-19 Vaccines against the Omicron Variant of SARS-CoV-2: A Review COVID-19疫苗对SARS-CoV-2 Omicron变体的疗效综述
Exploratory Research and Hypothesis in Medicine
Pub Date : 2023-09-04 DOI: 10.14218/erhm.2023.00023
K. S. Rajsri, Meena Singh, Mana Rao
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引用次数: 1
Anti-photoaging Properties of Asiaticoside in Ultraviolet A-irradiated Human Dermal Fibroblasts by Activating the PI3K-AKT Pathway and Inhibiting the NF-κB Pathway 通过激活PI3K-AKT通路和抑制NF-κB通路，积雪皂苷在紫外线照射人真皮成纤维细胞中的抗光老化特性
Exploratory Research and Hypothesis in Medicine
Pub Date : 2023-08-16 DOI: 10.14218/erhm.2023.00037
Jia Huang, Yiyi Gong, Li-Yu Daisy Liu, Jun Chen, Xiaobo Zhou
{"title":"Anti-photoaging Properties of Asiaticoside in Ultraviolet A-irradiated Human Dermal Fibroblasts by Activating the PI3K-AKT Pathway and Inhibiting the NF-κB Pathway","authors":"Jia Huang, Yiyi Gong, Li-Yu Daisy Liu, Jun Chen, Xiaobo Zhou","doi":"10.14218/erhm.2023.00037","DOIUrl":"https://doi.org/10.14218/erhm.2023.00037","url":null,"abstract":"","PeriodicalId":12074,"journal":{"name":"Exploratory Research and Hypothesis in Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79006718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Construction of Chinese Medicine Prescription Data Mining Based on Association Rules of the System 基于关联规则的中药处方数据挖掘系统构建
Exploratory Research and Hypothesis in Medicine
Pub Date : 2023-07-07 DOI: 10.14218/erhm.2023.00009
Jianwei Yang, Qiang Wang, Sida Zhou, Fen-Fen Zhang, Zhongdong Lv
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引用次数: 0
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