Evolution最新文献

The prevalence and strength of antibiotic resistance has led to an ongoing battle between the development of new treatments and the evolution of resistance. Combining multiple drugs simultaneously is a potential solution for combating antibiotic resistance. However, this approach introduces new factors that must be considered, including the influence of drug interactions on the rate of resistance evolution. When antibiotics are used in combination, their effects can be additive, synergistic, or antagonistic. In this study, we investigated the effect of higher-order interactions involving three drugs on resistance evolution in Staphylococcus epidermidis. Previous studies have shown that synergistic interactions can increase the adaptation rate. However, the effects of higher-order interactions on rates of adaptation are unclear. We investigated the adaptation of Staphylococcus epidermidis to single-, two-, and three-drug environments to assess how interactions within drug combinations influence the rate of adaptation. We analyzed both the overall interaction and emergent interaction, the latter being a unique interaction that occurs in three-drug combinations due to the presence of all three drugs, rather than simply strong pairwise interactions. Our results show that neither the overall interactions nor the emergent interactions affect adaptation rates.

How do water regime and herbivory shape phenotypic variation in plants along environmental gradients? Using a multifactorial field common garden approach, Jameel et al. (2024) showed that water availability and herbivore abundance influence the expression of foliar and reproductive traits in the perennial forb Boechera stricta. The concordance between phenotypic plasticity, phenotypic clines, and the direction of selection demonstrates the adaptive nature of plasticity in ecologically relevant traits. Furthermore, the experimental manipulations highlight which agents of selection drive the evolution of these traits.

Endosymbiotic reproductive manipulators are widely studied as sources of postzygotic isolation in arthropods, but their effect on prezygotic isolation between genetically differentiated populations has garnered less attention. We tested this using two partially isolated populations of the red and green color forms of Tetranychus urticae, either uninfected or infected with different Wolbachia strains, one inducing cytoplasmic incompatibility and the other not. We first investigated male and female preferences and found that, in absence of infection, females were not choosy, but all males preferred red-form females. Wolbachia effects were more subtle, with only the cytoplasmic incompatibility-inducing strain slightly strengthening color-form-based preferences. We then performed a double-mating experiment to test how incompatible matings affect subsequent mating behavior and offspring production as compared to compatible matings. Females mated with an incompatible male (infected and/or heterotypic) were more attractive and/or receptive to subsequent (compatible) matings, although analyses of offspring production revealed no clear benefit for this remating behavior (i.e., apparently unaltered first male sperm precedence). Finally, by computing the relative contributions of each reproductive barrier to total isolation, we showed that premating isolation matches both host-associated and Wolbachia-induced postmating isolation, suggesting that Wolbachia could contribute to reproductive isolation in this system.

During their radiation, certain groups of animals evolved significant phenotypic disparity (morphological diversity), enabling them to thrive in diverse environments. Adaptations to the same type of environment can lead to convergent evolution in function and morphology. However, well-documented examples in repeated adaptations of teleost fishes to different habitats, which are not primarily related to trophic specialization, are still scarce. Gobies are a remarkable fish group, exhibiting a great species diversity, morphological variability, and extraordinary ability to colonize very different environments. A variety of lifestyles and body forms evolved also in European lineages of gobies. We conducted two-dimensional geometric morphometric and phylomorphospace analyses in European lineages of gobies and evaluated the extent of convergent evolution in shape associated with adaptation to various habitats. Our analyses revealed the change in shape along the nektonic-cryptobenthic axis, from very slender head and body to stout body and wide head. We showed convergent evolution related to mode of locomotion in the given habitat in four ecological groups: nektonic, hyperbenthic, cryptobenthic, and freshwater gobies. Gobies, therefore, emerge as a highly diversified lineage with unique lifestyle variations, offering invaluable insights into filling of ecomorphological space and mechanisms of adaptation to various aquatic environments with distinct locomotion requirements.

Hybrid zones provide valuable opportunities to interrogate the processes that drive speciation. In a new study, Hardy et al. (2025) demonstrate that the dominant vegetation type in patchy cordgrass salt marshes and mangrove swamps drives a mosaic hybrid zone between two species of killifish. Furthermore, the authors showed that hybridization is asymmetrical, and that Fundulus grandis is more likely to hybridize than F. heteroclitus. This study highlights the need for interdisciplinary study of the environmental context of reproductive isolation.

Evolutionary theorists have emphasized for over half a century that population sampling must be conducted at the intergenerational boundary if the distinct effects of selection and inheritance are to be reliably quantified, with individuals recognized at the point of conception and lifetime reproductive success (LRS) defined as the total number of zygotic offspring produced per zygote. However, in those species whose ecology is otherwise well-suited to individual-level population studies, the prenatal part of an individual's life is often difficult to observe. While uncertainty has long surrounded the fertilization status of unhatched bird eggs-hatching failure can arise through fertilization failure or prenatal mortality-2 recent studies show fertilization failure to be extremely rare within 2 of the most popular avian study species. As such, unhatched eggs are highly reliable indicators of prenatal mortality. Although the generality of these results remains unclear, they demonstrate that prenatality can be incorporated into the observable lifespan of free-living animals. This allows zygotic LRS to be retrospectively quantified using historical nest observations and facilitates a more complete characterization of the evolutionary dynamics of wild populations.

The study of polyandry has received increasing scientific attention with an emphasis on the fitness benefits and costs that females derive from mating with multiple males. There are still gaps in our understanding of how polyandry affects female fitness, however, as many previous studies compared the fitness outcomes of a single mating vs. 2 or 3 matings and did not separate the consequences of multiple mating from the costs of sexual harassment. We, therefore, conducted controlled mating trials with female fruit flies (Drosophila melanogaster) that could mate at either low (every 8 days), medium (every 4 days), or high (every other day) rates while controlling for exposure to harassment from males. We found that female lifetime fitness was highest under the high mating-rate followed by the medium mating-rate conditions. Moreover, we did not detect reductions in lifespan as a consequence of higher rates of polyandry. Our results demonstrate that even at realistically high rates, polyandry can lead to net fitness benefits for females, which can have major implications for sexual selection. Specifically, we discuss the significance of our findings as they relate to competition and the evolution of secondary sex characteristics in females, and sperm competition among males.

I describe a simple model for quantifying the strength of association between two categorical characters evolving on a phylogenetic tree. The model can be used to estimate a correlation statistic that asks whether or not the two characters tend to change at the same time (positive correlation) or at different times (no correlation). This is different than asking if changes in one character are associated with a particular state in another character, which has been the focus of most prior tests for phylogenetic correlation in categorical characters. Analyses of simulated data indicate that positive correlations can be accurately estimated over a range of different tree sizes and phylogenetic signals.

Intraspecific variation is necessary for evolutionary change and population resilience, but the extent to which it contributes to either depends on the causes of this variation. Understanding the causes of individual variation in traits involved with reproductive timing is important in the face of environmental change, especially in systems where reproduction must coincide with seasonal resource availability. However, separating the genetic and environmental causes of variation is not straightforward, and there has been limited consideration of how small-scale environmental effects might lead to similarity between individuals that occupy similar environments, potentially biasing estimates of genetic heritability. In ecological systems, environments are often complex in spatial structure, and it may therefore be important to account for similarities in the environments experienced by individuals within a population beyond considering spatial distances alone. Here, we construct multi-matrix quantitative genetic animal models using over 11,000 breeding records (spanning 35 generations) of individually-marked great tits (Parus major) and information about breeding proximity and habitat characteristics to quantify the drivers of variability in two key seasonal reproductive timing traits. We show that the environment experienced by related individuals explains around a fifth of the variation seen in reproductive timing, and accounting for this leads to decreased estimates of heritability. Our results thus demonstrate that environmental sharing between relatives can strongly affect estimates of heritability and therefore alter our expectations of the evolutionary response to selection.

Hybridization offers insight into speciation and the forces that maintain barriers to reproduction, and hybrid zones provide excellent opportunities to test how environment shapes barriers to reproduction and hybrid fitness. A hybrid zone between the killifish, Fundulus heteroclitus and Fundulus grandis, had been identified in northeastern Florida, although the spatial structure and parameters that affect the distribution of the two species remain unknown. The present study aimed to determine the fine-scale spatial genetic patterns of the hybrid zone to test the hypothesis that species ranges are influenced by changes in dominant vegetation and to determine how differences in reproductive barriers between the two species influence the observed patterns. The area of overlap between the two species spanned ~37 km and showed a mosaic pattern of hybridization, suggesting the spatial structure of the hybrid zone is largely influenced by the environment. Environmental association analysis, however, suggested that while dominant vegetation had a significant influence on the spatial structure of the hybrid zone, a combination of environmental factors was driving the observed patterns. Hybridization tended to be rare at sites where F. heteroclitus was the more abundant species, suggesting that differences in preference for conspecifics can lead to differences in rates of introgression into parental taxa and likely result in a range-shift as opposed to adaptation in the face of climate change.