European Urology Open Science最新文献

{"title":"Super-resolution ultrasound imaging of the prostate, near-microscopic representation of normal and abnormal tissue","authors":"McNeill A., Gallagher K.G, Butler M., Papageorgiou G., Mobberley A., Grigorescu R., Keanie J., Good D., O’Donnell M., Leslie N., Lu W., Sboros V.","doi":"10.1016/S2666-1683(25)02523-6","DOIUrl":"10.1016/S2666-1683(25)02523-6","url":null,"abstract":"","PeriodicalId":12254,"journal":{"name":"European Urology Open Science","volume":"82 ","pages":"Page S29"},"PeriodicalIF":4.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145839235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Continuous quality improvement in TURBT: Experience from one centre with 45 years of prospectively collected data","authors":"Mariappan P., Hart-Brooke J., Smith G.","doi":"10.1016/S2666-1683(25)02516-9","DOIUrl":"10.1016/S2666-1683(25)02516-9","url":null,"abstract":"","PeriodicalId":12254,"journal":{"name":"European Urology Open Science","volume":"82 ","pages":"Pages S20-S21"},"PeriodicalIF":4.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145836417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The prognostic role of immunosuppressive tumour microenvironment biomarkers in renal cell cancer with venous tumour thrombus","authors":"Zapala L.P., Kunc M., Sharma S., Pęksa R., Popęda M., Radziszewski P.","doi":"10.1016/S2666-1683(25)02522-4","DOIUrl":"10.1016/S2666-1683(25)02522-4","url":null,"abstract":"","PeriodicalId":12254,"journal":{"name":"European Urology Open Science","volume":"82 ","pages":"Page S28"},"PeriodicalIF":4.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145839237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of surgery as a significant predictor of post-operative oncological and functional outcomes in patients submitted to radical prostatectomy: A video-based analysis","authors":"Suardi N.R., Nocera L., Furlan M.C., Mirabella G., Lonati C., Zamboni S., Ambrosini F., Mantica G., Terrone C.","doi":"10.1016/S2666-1683(25)02527-3","DOIUrl":"10.1016/S2666-1683(25)02527-3","url":null,"abstract":"","PeriodicalId":12254,"journal":{"name":"European Urology Open Science","volume":"82 ","pages":"Page S33"},"PeriodicalIF":4.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145839765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urorectal fistula repair after local treatment for prostate cancer: Long-term follow-up and patient-reported experience measures","authors":"Wagner M.C., Klemm J., Filipas D.K., Schulz R.J., Roessler N., Fisch M., Dahlem R., Vetterlein M.W.","doi":"10.1016/S2666-1683(25)02512-1","DOIUrl":"10.1016/S2666-1683(25)02512-1","url":null,"abstract":"","PeriodicalId":12254,"journal":{"name":"European Urology Open Science","volume":"82 ","pages":"Pages S14-S15"},"PeriodicalIF":4.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145839767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Copyright page","authors":"","doi":"10.1016/S2666-1683(25)02466-8","DOIUrl":"10.1016/S2666-1683(25)02466-8","url":null,"abstract":"","PeriodicalId":12254,"journal":{"name":"European Urology Open Science","volume":"82 ","pages":"Page I"},"PeriodicalIF":4.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145786491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The use of surgical AI in urology anno 2025","authors":"Mottrie A.","doi":"10.1016/S2666-1683(25)02504-2","DOIUrl":"10.1016/S2666-1683(25)02504-2","url":null,"abstract":"","PeriodicalId":12254,"journal":{"name":"European Urology Open Science","volume":"82 ","pages":"Page S5"},"PeriodicalIF":4.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145836354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A simplified modification of the lateral approach in nerve-sparing robotic radical prostatectomy: Technical description and early experience","authors":"Grivas N., Zabaftis C., Nikitakis F., Tsela S., Leotsakos I., Katafigiotis I., Karavitakis M.","doi":"10.1016/S2666-1683(25)02524-8","DOIUrl":"10.1016/S2666-1683(25)02524-8","url":null,"abstract":"","PeriodicalId":12254,"journal":{"name":"European Urology Open Science","volume":"82 ","pages":"Page S30"},"PeriodicalIF":4.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145839154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"25-year update of an artificial intelligence based (AIUSP) prospective prostate clinical monitoring trail: 1999-2025","authors":"Loch T.","doi":"10.1016/S2666-1683(25)02506-6","DOIUrl":"10.1016/S2666-1683(25)02506-6","url":null,"abstract":"","PeriodicalId":12254,"journal":{"name":"European Urology Open Science","volume":"82 ","pages":"Pages S7-S8"},"PeriodicalIF":4.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145839238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of H1 Antihistamines on Bacillus Calmette-Guérin–treated Non–muscle-invasive Bladder Cancer","authors":"Kang Liu ,&nbsp;Alex Qinyang Liu ,&nbsp;Hongda Zhao ,&nbsp;Chris Ho-Ming Wong ,&nbsp;Peter Ka-Fung Chiu ,&nbsp;Chi-Fai Ng ,&nbsp;Jeremy Yuen-Chun Teoh","doi":"10.1016/j.euros.2025.11.001","DOIUrl":"10.1016/j.euros.2025.11.001","url":null,"abstract":"<div><h3>Background and objective</h3><div>Concomitant H1 antihistamine (H1-AH) administration is associated with better survival outcomes for patients with metastatic urothelial carcinoma receiving immunotherapy. However, the role of H1-AHs among patients with non–muscle-invasive bladder cancer (NMIBC) treated with adjuvant intravesical bacillus Calmette-Guérin (BCG) immunotherapy has not been explored. Our aim was to investigate the impact of H1-AH use on survival outcomes for patients with BCG-treated NMIBC.</div></div><div><h3>Methods</h3><div>We conducted a territory-wide retrospective observational study. Patients with NMIBC who received intravesical immunotherapy with a single BCG strain in Hong Kong from 2001 to 2020 were identified. H1-AH prescription data were recorded. Overall survival (OS), cancer-specific survival (CSS), recurrence-free survival (RFS), and progression-free survival (PFS) outcomes were compared between H1-AH and control groups using the Kaplan-Meier method and multivariable Cox regression.</div></div><div><h3>Key findings and limitations</h3><div>Our analysis included 2028 patients with NMIBC who received intravesical BCG immunotherapy. Of these, 1539 patients (76%) had a H1-AH prescription at baseline and 489 (24%) never received any H1-AH prescription during the study period. Median follow-up was 11.0 yr. Kaplan-Meier analysis revealed that the H1-AH group had better CSS (<em>p</em> = 0.017) and PFS (<em>p</em> = 0.001). Subgroup analysis by H1-AH timing (before or during BCG therapy) showed that concomitant H1-AH treatment during intravesical BCG immunotherapy was associated with better CSS (<em>p</em> = 0.002) and PFS (<em>p</em> = 0.005). Multivariable Cox regression results demonstrated that concomitant H1-AH treatment was associated with better OS (hazard ratio [HR] 0.69, 95% confidence interval [CI] 0.58–0.82), CSS (HR 0.44, 95% CI 0.30–0.65), RFS (HR 0.81, 95% CI 0.67–0.98), and PFS (HR 0.64, 95% CI 0.45–0.91).</div></div><div><h3>Conclusions and clinical implications</h3><div>Concomitant H1-AH treatment was associated with better OS, CSS, RFS, and PFS for patients with NMIBC receiving adjuvant intravesical BCG.</div></div><div><h3>Patient summary</h3><div>The treatment for non–muscle-invasive bladder cancer (NMIBC) typically includes a solution of BCG (bacillus Calmette-Guérin) instilled into the bladder. We found better survival outcomes (overall survival, cancer-specific survival, recurrence-free survival, and progression-free survival) for patients who took a H1 antihistamine during their BCG treatment for intermediate-risk or high-risk NMIBC. More research is needed to confirm our results.</div></div>","PeriodicalId":12254,"journal":{"name":"European Urology Open Science","volume":"83 ","pages":"Pages 23-29"},"PeriodicalIF":4.5,"publicationDate":"2025-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145616056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}