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2017 International Conference on Intelligent Informatics and Biomedical Sciences (ICIIBMS)最新文献

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Multi-label classification of brain tumor mass spectrometry data In pursuit of tumor boundary detection method 多标签分类脑肿瘤质谱数据追求肿瘤边界检测方法
A. Sorokin, E. Zhvansky, K. Bocharov, I. Popov, Dmitry Zubtsov, A. Vorobiev, E. Nikolaev, V. Shurkhay, A. Potapov
The mass-spectrometry is the promising tool for the fast characterization of brain biopsy samples as a part of the intraoperative identification of tumor boundary. The spray-from-tissue ambient ionization method is a new instrument for mass-spectrometry analysis of soft tissues without sample preparation. In this contribution, we analyze the performance of multi-label classification techniques in detection of the tumor and necrosis fragments within the sample.
质谱法作为术中肿瘤边界识别的一部分,是快速表征脑活检样本的有前途的工具。组织环境电离喷雾法是一种无需制备样品的新型软组织质谱分析仪器。在这篇文章中,我们分析了多标签分类技术在检测样本中的肿瘤和坏死碎片方面的性能。
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引用次数: 6
Using mobile application as an instrument for ptosis diagnosis 使用手机应用程序作为上睑下垂诊断的工具
W. Kimpan, Pongpicha Sirivimonsattaya
This article proposes a novel of mobile application to help ophthalmologists diagnose the Ptosis disease. This application applied digital image processing techniques to identify eye parameters: Marginal Reflex Distance-1, Marginal Reflex Distance-2, and L/M Ratio which doctors can use to diagnose patients besides using naked eyes. The application was built for iOS platform in the first version. The inputs of the application are the images of patient's eyes from a mobile device camera or from a mobile device memory. After using digital image processing techniques, at the end of the process, the eye parameters will be displayed on the mobile device screen for the doctors to be used. The experimental results indicated that the proposed mobile application can perform with 86.36% of accuracy in measuring Marginal Reflex Distance-1 value while it can measure Marginal Reflex Distance-2 value with 63.64% of accuracy.
本文提出了一种新的移动应用程序,以帮助眼科医生诊断上睑下垂疾病。本应用采用数字图像处理技术识别眼部参数:Marginal Reflex Distance-1、Marginal Reflex Distance-2和L/M Ratio,医生可以利用这些参数来诊断患者。该应用程序的第一个版本是为iOS平台构建的。该应用程序的输入是来自移动设备摄像头或来自移动设备存储器的患者眼睛图像。使用数字图像处理技术后,在过程结束时,眼睛参数将显示在移动设备屏幕上,供医生使用。实验结果表明,该移动应用程序测量边缘反射距离-1值的准确度为86.36%,测量边缘反射距离-2值的准确度为63.64%。
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引用次数: 0
Verification experiment for drone charging station using RTK-GPS RTK-GPS无人机充电站验证实验
Suriyon Tansuriyong, Motoki Kyan, Kaito Numata, Shuuya Taira, T. Anezaki
In recent years, Drone's research has become popular, and there is a need to automate the cycle of takeoff, flight, landing, and charging of Drone. Mainly, the problem remains in automatic battery charging. Therefore, in this research, we will realize Drone's charging station using RTK-GPS with high accuracy. We verified the landing accuracy by experiment. From the results of the verification, it was found that relative positional error between drone and the charging station can be eliminated by referring to the same reference position. Thus, the possibility of navigating Drone to the charging station can be easily implemented.
近年来,Drone的研究开始流行,需要实现无人机起飞、飞行、降落、充电的自动化循环。问题主要存在于电池自动充电方面。因此,在本研究中,我们将使用高精度的RTK-GPS来实现无人机充电站。通过实验验证了着陆精度。验证结果表明,采用相同的参考位置可以消除无人机与充电站之间的相对位置误差。因此,可以很容易地实现将无人机导航到充电站的可能性。
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引用次数: 4
High-voltage driving circuit with on-chip ESD protection in CMOS technology 采用CMOS技术的片上ESD保护的高压驱动电路
Chun-Yu Lin, Yan-Lian Chiu
A high-voltage / high-power driving circuit for the applicatrions such as a motor controller in robot is presented in this work. The driving circuit is further equipped with a novel electrostatic discharge (ESD) protection design to enhance its reliability. A 3×VDD-tolerant driving circuit with on-chip ESD protection is demonstrated using a 0.18 μm CMOS process with Vdd of 3.3V. The ESD robustness can be improved without the use of any additional ESD protection device or layout area. Furthermore, this design technique can be used for an n∗Vdd-tolerant driving circuit with improved ESD robustness.
提出了一种适用于机器人电机控制器等应用的高压大功率驱动电路。驱动电路还采用了新颖的静电放电保护设计,提高了电路的可靠性。采用0.18 μm CMOS工艺,Vdd为3.3V,设计了具有片内ESD保护的3×VDD-tolerant驱动电路。无需使用任何额外的ESD保护装置或布局区域,即可提高ESD稳健性。此外,该设计技术可用于具有改善ESD稳健性的n * vdd耐受性驱动电路。
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引用次数: 1
Experimental evaluation of an assist chair for sit-to-stand on speed of flipping up a seat of chair 一种坐立辅助椅对翻转椅座速度的实验评价
N. T. T. Suzuki, A. Suda, H. Onishi, T. Muromaki, T. Watanabe
Assist chairs with simple mechanism to flip up a seat at the front edge to assist sit-to-stand (STS) is well known as commercial products developed from around 1980. The speed of flipping up the seat on the assist chairs would play a key role how to adjust assisting STS in individual cases, but there is almost no discussion how the speed of flipping up the seat affects the benefit of assisting STS. The aim of study is to investigate the optimised speed of flipping up the seat of the assist chairs. As a first step, a motorised assist chair with controllable speed of flipping up the seat was developed and tested with four healthy participants in three seat height conditions; High:520mm, Middle:420mm, and Low:320mm without and with flipping up the seat at maximum speed 30degree/second. Significant main effect of assisting was found on peak vGRF at Low seat height (p<0.005) by Wilcoxon rank test. There was no significant effect at Middle (p=0.126) and High seat height (p=0.507). With assisting at the Low seat height, the reduction of peak vGRF means that the flipping up the seat successfully supports trunk movement and knee function to lift up the hip from the seat. All participants felt the assisting was effective to reduce the hardness of STS at the Low seat height. With further studies to optimise the speed of flipping the seat, the motorised assist chair in this study would provide a proper assist for individual STS movement, with leaving certain part of physical load for keeping muscle functioning.
辅助椅是1980年左右发展起来的一种商业产品,它具有简单的机构,可以将前面的座位翻转起来,以辅助坐立。在个别情况下,辅助座椅的掀座速度对辅助STS的调整起到关键作用,但几乎没有讨论掀座速度如何影响辅助STS的效益。研究的目的是研究辅助座椅翻转的最佳速度。作为第一步,研究人员开发了一种机动辅助椅,可控制翻转座椅的速度,并在三种座椅高度条件下对四名健康参与者进行了测试;高:520mm,中:420mm,低:320mm,不带和带翻转阀座,最高速度30度/秒。Wilcoxon秩检验发现,辅助对低座高vGRF峰值有显著的主效应(p<0.005)。中座高度(p=0.126)和高座高度(p=0.507)无显著影响。在低座椅高度的辅助下,降低峰值vGRF意味着翻转座椅成功地支持躯干运动和膝盖功能,以将臀部从座椅上抬起。所有参加者都认为,在座位高度较低的情况下,协助能有效减低STS的硬度。随着进一步研究以优化翻转座椅的速度,本研究中的电动辅助椅将为个别STS运动提供适当的辅助,并留下部分物理负荷以保持肌肉功能。
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引用次数: 2
Real-time object classification for autonomous vehicle using LIDAR 基于激光雷达的自动驾驶车辆实时目标分类
Masaru Yoshioka, N. Suganuma, Keisuke Yoneda, Mohammad Aldibaja
Object classification is an important issue in order to bring autonomous vehicle into reality. In this paper, real-time and robust classification based on Real AdaBoost algorithm is researched and improved. Various effective features of road objects are computed using LIDAR 3D point clouds. The improved classifier provides an accuracy of over 90 (%) in a range of 50 (m) and classifies objects into car, pedestrian, bicyclist and background. Moreover, processing time of classifying an object consumes only 0.07∗10−3 (sec) that enables this method to be used for autonomous driving on urban roads.
目标分类是实现自动驾驶汽车的一个重要问题。本文研究并改进了基于Real AdaBoost算法的实时鲁棒分类。利用激光雷达三维点云计算道路物体的各种有效特征。改进后的分类器在50米范围内提供了超过90%的准确率,并将物体分为汽车、行人、自行车和背景。此外,分类对象的处理时间仅为0.07∗10−3 (sec),使该方法能够用于城市道路上的自动驾驶。
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引用次数: 27
FF OCT with a swept source integrating a SLD and an AOTF 带扫描源的FF OCT集成了SLD和atf
Ting-Wei Chang, Hung-Chih Chiang, Chir-Weei Chang, Chy-Lin Wang, Yuan-Chin Lee
A full-field optical coherence tomography with a swept source integrating a superluminescent diode and an acousto-optic tunable filter is designed, implemented, and tested. The center wavelength and the bandwidth of the swept source are 840nm and 50nm, respectively. There are estimated about 688 laser lines generated in a sweep cycle. For convenience, a Mirau objective lens is adopted to simplify the system structure. Some preliminary experiments were conducted by using the system, and an onion was adopted as the sample. Two clear restored 3D images of the onion were obtained by using two different algorithms. The differences between the two images were also compared with each other. Further improvement and experiments by using this system are still in progress.
设计、实现并测试了一个集成超发光二极管和声光可调滤波器的扫描源的全场光学相干层析成像。扫描光源的中心波长为840nm,带宽为50nm。估计在一个扫描周期中产生大约688条激光线。为方便起见,采用了Mirau物镜,简化了系统结构。利用该系统进行了初步实验,并以洋葱为样品。使用两种不同的算法获得了两幅清晰的洋葱三维图像。并对两幅图像的差异进行了比较。使用该系统的进一步改进和实验仍在进行中。
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引用次数: 0
Optimal window lengths, features and subsets thereof for freezing of gait classification 冻结步态分类的最佳窗口长度、特征及其子集
V. Mikos, C. Heng, A. Tay, N. S. Chia, K. Koh, D. Tan, W. Au
Freezing of gait (FoG) is a common gait impairment in Parkinson's disease that puts patients at risk of falls and deteriorates their quality of life. Relief is sought after by evaluating the possibility of wearable systems that detect FoG in real-time and provide gait-reinforcing biofeedback cues. The successful detection relies on the extraction of high quality features, which have to be computed from recent samples of an inertial measurement unit in order to ensure real-time applicability. Unfortunately, the amount of samples considered for a feature's computation, i.e. the data window length, has been subjected to widespread disagreement: With no thorough analysis available, employed window lengths differed by several seconds among implementations. We derive optimal window lengths for a broad number of features used throughout literature by using mutual information as an evaluation metric, and elaborate on a window length's significance in affecting classification performance. With conventional feature selection methods, feature subsets tailored to various machine learning algorithms are established. Relying on these feature subsets for FoG classification, whereby all features are extracted with optimal window lengths, F1-scores increase up to 17.1% for individual classifiers and up to 12.7% on average when compared to previously proposed feature sets that are extracted with sub-optimal window lengths.
步态冻结(FoG)是帕金森病中常见的步态障碍,使患者有跌倒的风险,并使他们的生活质量恶化。通过评估可穿戴系统实时检测FoG并提供增强步态的生物反馈线索的可能性,人们寻求缓解。成功的检测依赖于高质量特征的提取,这些特征必须从最近的惯性测量单元样本中计算,以确保实时适用性。不幸的是,用于特征计算的样本数量,即数据窗口长度,一直受到广泛的分歧:由于没有彻底的分析,所采用的窗口长度在实现之间相差几秒。我们通过使用互信息作为评估指标,为文献中使用的大量特征推导出最佳窗口长度,并详细说明窗口长度在影响分类性能方面的重要性。利用传统的特征选择方法,建立适合各种机器学习算法的特征子集。依靠这些特征子集进行FoG分类,其中所有特征都是用最优窗口长度提取的,与之前提出的以次优窗口长度提取的特征集相比,单个分类器的f1分数提高了17.1%,平均提高了12.7%。
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引用次数: 4
Primary screening of diabetic retinopathy based on integrating morphological operation and support vector machine 基于形态学操作和支持向量机的糖尿病视网膜病变初步筛查
Syna Sreng, Noppadol Maneerat, D. Isarakorn, K. Hamamoto, Ronakorn Panjaphongse
Diabetic retinopathy is one of the most frequent causes of blindness due to diabetes. Primary screening is essential due to prerequisite step toward the diagnosis of diabetic retinopathy in order to prevent vision loss or blindness. This paper presents the methods to discriminate between healthy images and diabetic retinopathy images on the retinal images. The proposed method involves three main steps. Initially, the image is preprocessed to remove small noises and enhance the contrast of the image. Secondly, Kirsch edge detection is utilized to detect the bright lesions. Subsequently, the red lesions are detected depending on top-hat morphological filtering methods. Then the bright and dark lesions are combined by using logical AND operator. In order to be left only pathological signs, the noises near the vicinity of the optic disc and blood vessels are further removed using blob analysis. Finally, morphological features are extracted and fed to the SVM classifier. The proposed method was evaluated with three datasets containing 229 images. It achieved the accuracy of 90%, sensitivity of 86.33% and specificity of 98.55% with the average computational time 8 seconds per image. The method is simple and fast, easy to implement and the result is promising.
糖尿病视网膜病变是糖尿病致盲的最常见原因之一。为了防止视力丧失或失明,初级筛查是诊断糖尿病视网膜病变的先决步骤。本文提出了在视网膜图像上区分健康图像和糖尿病视网膜病变图像的方法。提出的方法包括三个主要步骤。首先对图像进行预处理,去除小噪声,增强图像的对比度。其次,利用Kirsch边缘检测检测明亮病灶;随后,根据顶帽形态滤波方法检测红色病变。然后利用逻辑与运算符将明暗病灶进行组合。为了只留下病理征象,视盘和血管附近的噪声进一步用斑点分析去除。最后,提取形态学特征并将其输入到SVM分类器中。用三个包含229张图像的数据集对该方法进行了评估。该方法的准确率为90%,灵敏度为86.33%,特异性为98.55%,平均计算时间为8秒/幅。该方法简单快速,易于实现,效果良好。
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引用次数: 5
A hybrid of data mining and ensemble learning forecasting for recurrent ovarian cancer 基于数据挖掘和集成学习的复发性卵巢癌预测
Y. Lu, Chi-Jie Lu, Chi-Chang Chang, Yu-Wen Lin
This study applied advanced machine learning techniques and combined with ensemble learning, widely considered as the most successful method to produce objective to an inferential problem of recurrent ovarian cancer. In this study, five machine learning approaches including SVM(support vector machine), C5.0, ELM(extreme learning machine), MARS(Multivariate Adaptive Regression Splines) and RF(Random Forests) were considered to find important risk factors and to predict the recurrence-proneness for ovarian cancer. We use ensemble learning to improve the defect of classification accuracy used normal machine learning: first, selecting important risk factors by ensemble learning, then, using the five machine learning approaches to analyze again. The medical records and pathology were accessible by the Chung Shan Medical University Hospital Tumor Registry. The existing literature on recurrent ovarian cancer reveals that factors include Age, Histology, Grade, Pathologic T, Pathologic N, Pathologic M, Pathologic Stage, The International Federation of Gynecology and Obstetrics (FIGO), Surgical Margins, Performance status, CA125, Operation Optimal Debulking, Chemotherapy Guideline. There are totally 987 patients in the data set. In our study, C5.0 is the superior approach in predicting recurrence of ovarian cancer. Moreover, the classification accuracy of C5.0, MARS, RF and SVM indeed increases after using ensemble learning. Particularly the classification accuracy of C5.0 obviously improves by using ensemble learning with hybrid scheme.
本研究应用先进的机器学习技术,并结合集成学习,被广泛认为是最成功的方法来产生客观的卵巢癌复发推理问题。本研究采用支持向量机SVM(support vector machine)、C5.0、极限学习机ELM(extreme learning machine)、多变量自适应回归样条(Multivariate Adaptive Regression Splines)和随机森林RF(Random Forests) 5种机器学习方法发现卵巢癌的重要危险因素并预测卵巢癌的复发倾向。我们使用集成学习来改善常规机器学习的分类精度缺陷:首先,通过集成学习选择重要的危险因素,然后,使用五种机器学习方法进行再次分析。医疗纪录及病理资料可于中山医科大学附属医院肿瘤登记处查阅。现有文献显示,卵巢癌复发的影响因素包括:年龄、组织学、分级、病理T、病理N、病理M、病理分期、国际妇产科联合会(FIGO)、手术切缘、运动状态、CA125、手术最佳减积、化疗指南。数据集中共有987例患者。在我们的研究中,C5.0是预测卵巢癌复发的最佳方法。此外,使用集成学习后,C5.0、MARS、RF和SVM的分类准确率确实有所提高。特别是采用混合方案的集成学习明显提高了C5.0的分类精度。
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引用次数: 3
期刊
2017 International Conference on Intelligent Informatics and Biomedical Sciences (ICIIBMS)
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