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Comparisons of Yield, Amino Acid Composition and Antioxidant Activity of the Ten Extracts of Gryllus bimaculatus (Two-Spotted Cricket) Prepared by Different Methods 不同方法制备双斑蟋蟀10种提取物的产率、氨基酸组成及抗氧化活性比较
Pub Date : 2021-01-01 DOI: 10.52361/fsbh.2021.1.e41
W. Jeong, Chul-Jai Kim, An-Na Kim, Younggi Choi, Jong Rae Kim, M. Jeong, Y. Jeong, Joong-Hark Kim
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引用次数: 1
The In vitro Evidence that Ethanol Extract of Aronia (Aronia melanocarpa) Fruits Inhibits the Inflammatory Response of Macrophages Stimulated by Particulate Matter2.5 野樱果乙醇提取物抑制颗粒物质2.5刺激巨噬细胞炎症反应的体外实验证据
Pub Date : 2021-01-01 DOI: 10.52361/fsbh.2021.1.e45
H. Kim, Yujung Kim, Ya Zhang, Min-Chul Lee, A. Om
{"title":"The In vitro Evidence that Ethanol Extract of Aronia (Aronia melanocarpa) Fruits Inhibits the Inflammatory Response of Macrophages Stimulated by Particulate Matter2.5","authors":"H. Kim, Yujung Kim, Ya Zhang, Min-Chul Lee, A. Om","doi":"10.52361/fsbh.2021.1.e45","DOIUrl":"https://doi.org/10.52361/fsbh.2021.1.e45","url":null,"abstract":"","PeriodicalId":12362,"journal":{"name":"Food Supplements and Biomaterials for Health","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73072215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Study on Toxicity of Cornus alba L. Extract in Sprague Dawley Rats 山茱萸提取物对大鼠的毒性研究
Pub Date : 2021-01-01 DOI: 10.52361/fsbh.2021.1.e43
Ki Cheon Kim, T. Jeong, Singeun Kim, Kyung-Mi Kim, M. Choi, Jae-Chul Jung, Min-Won Lee, P. Jeong
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引用次数: 2
In Vitro Evidence for Inhibitory Action of Hydrangea serrata (Thunb.) Ser. Leaf Extract on Urate Crystal-Induced inflammation 刺绣球体外抑菌作用的研究爵士。叶提取物对尿酸盐晶体诱导炎症的影响
Pub Date : 2021-01-01 DOI: 10.52361/fsbh.2021.1.e27
Changseon Na, Hyun Jae Kim, H. Ahn, Yu-Kyong Shin, S. H. Lee
{"title":"In Vitro Evidence for Inhibitory Action of Hydrangea serrata (Thunb.) Ser. Leaf Extract on Urate Crystal-Induced inflammation","authors":"Changseon Na, Hyun Jae Kim, H. Ahn, Yu-Kyong Shin, S. H. Lee","doi":"10.52361/fsbh.2021.1.e27","DOIUrl":"https://doi.org/10.52361/fsbh.2021.1.e27","url":null,"abstract":"","PeriodicalId":12362,"journal":{"name":"Food Supplements and Biomaterials for Health","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81134252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Effects of Astragalus Extract Mixture HT042 on H295R Steroidogenesis and Hershberger Assay 黄芪合剂HT042对H295R甾体生成及Hershberger试验的影响
Pub Date : 2021-01-01 DOI: 10.52361/FSBH.2021.1.E11
Donghun Lee, Sung Hyun Lee, Hocheol Kim
Astragalus extract mixture HT042 is a standardized functional herbal food approved by the Ministry of Food and Drug Safety to help height-growth in children. This study aimed to illustrate the potential of a HT042 involved in shorten the growth period. The in vitro H295R steroidogenesis assay and in vivo Hershberger assay were conducted to examine the effect of HT042. The results showed that HT042 had no effects on progesterone, estradiol and testosterone production in H295R cell steroidogenesis assay and on androgenic activity of castrated groups rats in Hershberger assay. Thus, HT042 has not influenced changes in sex steroid hormones and androgenic activities, which can shorten the growth period in in vitro and in vivo assays performed.
黄芪提取合剂HT042是食品药品安全部批准的一种促进儿童长高的标准化功能性草药食品。本研究旨在阐明HT042参与缩短生长期的潜力。采用体外H295R甾体生成法和体内Hershberger法检测HT042的作用。结果表明,HT042对H295R细胞甾体生成实验中黄体酮、雌二醇和睾酮的产生及Hershberger实验中去势组大鼠雄激素活性均无影响。因此,在体外和体内实验中,HT042没有影响性类固醇激素和雄激素活性的变化,从而缩短了生长期。
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引用次数: 0
Immunoenhancing Effects of Korean Red Ginseng Powder in BALB/c Mice Treated with Cyclophosphamide 红参粉对环磷酰胺治疗BALB/c小鼠的免疫增强作用
Pub Date : 2021-01-01 DOI: 10.52361/fsbh.2021.1.e46
Mi-Hyang Lee, J. Kyung, Sung Won Kim, Gyo In, Chae-Kyu Park, S. Hyun
{"title":"Immunoenhancing Effects of Korean Red Ginseng Powder in BALB/c Mice Treated with Cyclophosphamide","authors":"Mi-Hyang Lee, J. Kyung, Sung Won Kim, Gyo In, Chae-Kyu Park, S. Hyun","doi":"10.52361/fsbh.2021.1.e46","DOIUrl":"https://doi.org/10.52361/fsbh.2021.1.e46","url":null,"abstract":"","PeriodicalId":12362,"journal":{"name":"Food Supplements and Biomaterials for Health","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88385095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
My Opinion on the Report of ILSI Korea on ‘System of Function Claims for the General Food’ 我对ILSI韩国关于“一般食品功能声明体系”的报告的看法
Pub Date : 2021-01-01 DOI: 10.52361/fsbh.2021.1.e39
Y. Sheen
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引用次数: 1
Toxicodendron vernicifluum (sumac) Inhibits Mast Cell Degranulation by Suppressing the Syk/PLCγ Signaling Pathway in RBL-2H3 Cells 漆树通过抑制RBL-2H3细胞Syk/PLCγ信号通路抑制肥大细胞脱颗粒
Pub Date : 2021-01-01 DOI: 10.52361/fsbh.2021.1.e44
Jiyoon Choi, Hye Lim Hong, Seunghan Sun, K. Oh, C. Na, Hye-Hyun Yoo, Yongseok Choi, Young In Park, M. Dong
{"title":"Toxicodendron vernicifluum (sumac) Inhibits Mast Cell Degranulation by Suppressing the Syk/PLCγ Signaling Pathway in RBL-2H3 Cells","authors":"Jiyoon Choi, Hye Lim Hong, Seunghan Sun, K. Oh, C. Na, Hye-Hyun Yoo, Yongseok Choi, Young In Park, M. Dong","doi":"10.52361/fsbh.2021.1.e44","DOIUrl":"https://doi.org/10.52361/fsbh.2021.1.e44","url":null,"abstract":"","PeriodicalId":12362,"journal":{"name":"Food Supplements and Biomaterials for Health","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86749168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of the Properties of the Extracts Prepared by a Supercritical Carbon Dioxide Method under Four Different Conditions 四种不同条件下超临界二氧化碳萃取物的性质比较
Pub Date : 2021-01-01 DOI: 10.52361/fsbh.2021.1.e42
Wonseok Kang, J. Auh
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引用次数: 0
Tumeric Ethanol Extract Up-regulated the Lipolysis by Activation of Lipase Related Pathway in HepG2 Cells 姜黄乙醇提取物通过激活脂肪酶相关通路上调HepG2细胞的脂肪分解
Pub Date : 2021-01-01 DOI: 10.52361/FSBH.2021.1.E13
D. Oh, Dakyung Kim, Minhee Lee, Jeongmin Lee
In current, we investigated the effect of tumeric ethanol extract (TEE) on underlying mechanisms of lipolysis in HepG2 hepatocytes. The intracellular lipid droplets were stained and quantified. In comparison with the control, lipid accumulation with 72-hours treatment of TEE was significantly decreased by 25.8% at concentration of 100 µg/mL. In consistence with a result, the cellular triglyceride (TG) content was reduced by 22.3% at concentration of 100 µg/mL, respectively. To determine the action mode of reduction in TG content, the glycerol release and level of glucose uptake were measured. At first, incubation of HepG2 hepatocytes with 50 and 100 g/mL of TEE for 4 hours significantly decreased the extracellular uptake of glucose by 7.4% and 10.4%. The free glycerol level released into the cultured media were significantly increased with 50 and 100 µg/mL of TEE treatment by 20.8% and 29.1%, but there was no time-dependent effect. As subsequently measured by quantitative real-time polymerase chain reaction, mRNA level of hormone-sensitive lipase (HSL) and adipose triglyceride lipase (ATGL), but not lipoprotein lipase (LPL), was significantly increased by 25.2% and 31.1% at concentration of 100 µg/mL. The present study suggested that TEE partially inhibited lipogenesis by suppressing glucose uptake and enhanced lipolysis through upregulation of HSL and ATGL mRNA expression, resulting in increased glycerol release.
目前,我们研究了姜黄乙醇提取物(TEE)对HepG2肝细胞脂肪分解的潜在机制的影响。对细胞内脂滴进行染色和定量。与对照组相比,TEE浓度为100µg/mL,处理72小时后脂质积累显著减少25.8%。结果表明,当浓度为100µg/mL时,细胞甘油三酯(TG)含量分别降低22.3%。为了确定降低TG含量的作用方式,测量了甘油释放量和葡萄糖摄取水平。首先,HepG2肝细胞与50和100 g/mL TEE孵卵4小时后,细胞外葡萄糖摄取显著降低7.4%和10.4%。50µg/mL和100µg/mL TEE处理后,释放到培养基中的游离甘油水平分别显著提高20.8%和29.1%,但不存在时间依赖性。随后通过实时定量聚合酶链反应测定,在100µg/mL浓度下,激素敏感脂肪酶(HSL)和脂肪甘油三酯脂肪酶(ATGL) mRNA水平显著升高25.2%和31.1%,而脂蛋白脂肪酶(LPL) mRNA水平未见显著升高。本研究提示,TEE通过上调HSL和ATGL mRNA表达,抑制葡萄糖摄取和促进脂肪分解,从而增加甘油释放,从而部分抑制脂肪生成。
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引用次数: 0
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