M. Choi, Kyung-Mi Kim, Euna Cho, T. Jeong, Jae-Chul Jung
Health functional food (HFF) is managed in a various type and different regulations in each country. It is largely composed of notified HFF and recognized HFF in Korea. We described the process of registering the raw materials of HFF in Korea and details of the registration of recognition of Sophora japonica L. Fruit Extract for excellent female menopausal efficacy. To have a valid Health Claim of food ingredients, recognition of the ingredients must be obtained from Ministry of Food and Drug Safety. In order to register the recognition of HFF, it is required to have sufficient scientific evidences on standardization of raw materials, verification of functional efficacy and safety.
{"title":"A Practical Registration Procedure of Korean Health Functional Food Ingredient: The Registration of Sophora japonica L., Fruit Extract for Excellent Female Menopausal Efficacy","authors":"M. Choi, Kyung-Mi Kim, Euna Cho, T. Jeong, Jae-Chul Jung","doi":"10.52361/FSBH.2021.1.E1","DOIUrl":"https://doi.org/10.52361/FSBH.2021.1.E1","url":null,"abstract":"Health functional food (HFF) is managed in a various type and different regulations in each country. It is largely composed of notified HFF and recognized HFF in Korea. We described the process of registering the raw materials of HFF in Korea and details of the registration of recognition of Sophora japonica L. Fruit Extract for excellent female menopausal efficacy. To have a valid Health Claim of food ingredients, recognition of the ingredients must be obtained from Ministry of Food and Drug Safety. In order to register the recognition of HFF, it is required to have sufficient scientific evidences on standardization of raw materials, verification of functional efficacy and safety.","PeriodicalId":12362,"journal":{"name":"Food Supplements and Biomaterials for Health","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81057504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mun-Hoe Lee, Jae-Min Hwang, E. Kang, Hyeong-Min Kim, Sung-Woo Yoon, H. Chung, Jin-Hee Lee
Licorice, the root of Glycyrrhiza glabra , has been reported to exhibit an anti-obesity effect. Here the anti-obesity effect of licorice acetone extract (LE) standardized by glabridin content was examined by oral administration of 50 or 100 mg/kg per day of LE for 12 weeks in C57BL/6N mice with high-fat-diet-induced obesity. Body-weight gain and epididymal fat mass, which were increased by the induction of obesity, were decreased significantly in mice treated with LE. Serum levels of total cholesterol, aspartate aminotransferase, and alanine aminotransferase, in addition to the adipocyte size of epididymal fat and hepatic steatosis, were ameliorated by LE treatment. Furthermore, LE regulated the expression levels of acetyl-CoA carboxylase and peroxisome proliferator-activated receptor gamma in the liver. In particular, LE increased serum adiponectin strongly, which inhibited lipid anabolism and promoted lipid catabolism. These findings suggest that licorice extracted with acetone has anti-obesity effects.
{"title":"Anti-Obesity Effect of Licorice Acetone Extract in a Mouse Model of Obesity Induced by a High-Fat Diet","authors":"Mun-Hoe Lee, Jae-Min Hwang, E. Kang, Hyeong-Min Kim, Sung-Woo Yoon, H. Chung, Jin-Hee Lee","doi":"10.52361/FSBH.2021.1.E8","DOIUrl":"https://doi.org/10.52361/FSBH.2021.1.E8","url":null,"abstract":"Licorice, the root of Glycyrrhiza glabra , has been reported to exhibit an anti-obesity effect. Here the anti-obesity effect of licorice acetone extract (LE) standardized by glabridin content was examined by oral administration of 50 or 100 mg/kg per day of LE for 12 weeks in C57BL/6N mice with high-fat-diet-induced obesity. Body-weight gain and epididymal fat mass, which were increased by the induction of obesity, were decreased significantly in mice treated with LE. Serum levels of total cholesterol, aspartate aminotransferase, and alanine aminotransferase, in addition to the adipocyte size of epididymal fat and hepatic steatosis, were ameliorated by LE treatment. Furthermore, LE regulated the expression levels of acetyl-CoA carboxylase and peroxisome proliferator-activated receptor gamma in the liver. In particular, LE increased serum adiponectin strongly, which inhibited lipid anabolism and promoted lipid catabolism. These findings suggest that licorice extracted with acetone has anti-obesity effects.","PeriodicalId":12362,"journal":{"name":"Food Supplements and Biomaterials for Health","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90938406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Min Yu, Hee Joon Jun, Y. Son, Cheol-Beum Park, J. Hong, D. Son
Antarctic krill (Euphausia superba) oil has emerged as a potential alternative for omega-3 supplementation and that has been shown to reduce cardiovascular disease risk. However, all relevant current krill oil extraction methodologies generally use organic solvents which could leave solvent residues on the final product. Hence, we established a solvent-free method for the krill oil production by using proteases and evaluated the inhibitory effect of enzymatically decomposed krill oil (EDKO) on vascular endothelial inflammation and atherosclerotic plaque formation and its underlying mechanism. We investigated the effect of EDKO treatment on vascular inflammatory gene expression changes in vivo using partial carotid ligation and intimal endothelial-enriched total RNA extraction methods in C57BL/6 mice. In addition, the effect of EDKO dietary treatment on atherosclerosis development was examined by acuteand chronic-models of atherosclerosis in apolipoprotein E knockout (ApoE−/−) mice. Our results showed administration of EDKO by oral gavage down-regulated the proinflammatory genes (vascular cell adhesion protein 1, intercellular adhesion molecule 1, chitinase 3 like 1, and chemokine [C-C motif ] ligand 19) expression in arterial endothelium. Furthermore, we showed that dietary treatment of EDKO potently inhibited atherosclerotic plaque formation in both acuteand chronic model of atherosclerosis in ApoE−/− mice. Our findings suggest that dietary supplementation of EDKO provides anti-atherogenic benefits by inhibiting vascular inflammation through regulating pro-atherogenic and anti-atherogenic genes expression in arterial endothelium.
{"title":"Enzymatically Decomposed Antarctic Krill Oil Inhibits Atherosclerosis by Suppressing the Vascular Endothelial Inflammation","authors":"Min Yu, Hee Joon Jun, Y. Son, Cheol-Beum Park, J. Hong, D. Son","doi":"10.52361/FSBH.2021.1.E9","DOIUrl":"https://doi.org/10.52361/FSBH.2021.1.E9","url":null,"abstract":"Antarctic krill (Euphausia superba) oil has emerged as a potential alternative for omega-3 supplementation and that has been shown to reduce cardiovascular disease risk. However, all relevant current krill oil extraction methodologies generally use organic solvents which could leave solvent residues on the final product. Hence, we established a solvent-free method for the krill oil production by using proteases and evaluated the inhibitory effect of enzymatically decomposed krill oil (EDKO) on vascular endothelial inflammation and atherosclerotic plaque formation and its underlying mechanism. We investigated the effect of EDKO treatment on vascular inflammatory gene expression changes in vivo using partial carotid ligation and intimal endothelial-enriched total RNA extraction methods in C57BL/6 mice. In addition, the effect of EDKO dietary treatment on atherosclerosis development was examined by acuteand chronic-models of atherosclerosis in apolipoprotein E knockout (ApoE−/−) mice. Our results showed administration of EDKO by oral gavage down-regulated the proinflammatory genes (vascular cell adhesion protein 1, intercellular adhesion molecule 1, chitinase 3 like 1, and chemokine [C-C motif ] ligand 19) expression in arterial endothelium. Furthermore, we showed that dietary treatment of EDKO potently inhibited atherosclerotic plaque formation in both acuteand chronic model of atherosclerosis in ApoE−/− mice. Our findings suggest that dietary supplementation of EDKO provides anti-atherogenic benefits by inhibiting vascular inflammation through regulating pro-atherogenic and anti-atherogenic genes expression in arterial endothelium.","PeriodicalId":12362,"journal":{"name":"Food Supplements and Biomaterials for Health","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87477610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Donghoon Kim, Inbae Ji, Kwideok Han, John N. Ng’ombe
This study analyzes the consumer characteristics of health functional food intake by major product, and measures the national health expenditure saved due to the intake. Our survey of 1,210 consumers covers the current state of their health functional food intake and their consequently reduced medical expenses. Using a probit model, this study analyzes the characteristics of the consumers' intake of each of the seven major products: multivitamins, red ginseng, probiotics, lutein, eicosapentaenoic acid/docosahexaenoic acid oils, single vitamins, and propolis. The results show that women have a higher probability of consuming these products than men. However, younger consumers are more likely to take multivitamins and probiotics, while older consumers are more likely to consume lutein, eicosapentaenoic acid/docosahexaenoic acid oils, and propolis products. For most products, a higher income level increases the probability of taking them. On the other hand, the national health expenditure saved due to consumers' intake of health functional foods is estimated to be approximately 8.952 trillion won (about USD 8 billion), which includes about 2.202 trillion won (about USD 1.95 billion) in the private sector and approximately 6.750 trillion won (about USD 5.98 billion) in the public sector.
{"title":"Effects of Consumer Characteristics on the Intake of Health Functional Foods: Implications for National Health Expenditure Savings","authors":"Donghoon Kim, Inbae Ji, Kwideok Han, John N. Ng’ombe","doi":"10.52361/FSBH.2021.1.E3","DOIUrl":"https://doi.org/10.52361/FSBH.2021.1.E3","url":null,"abstract":"This study analyzes the consumer characteristics of health functional food intake by major product, and measures the national health expenditure saved due to the intake. Our survey of 1,210 consumers covers the current state of their health functional food intake and their consequently reduced medical expenses. Using a probit model, this study analyzes the characteristics of the consumers' intake of each of the seven major products: multivitamins, red ginseng, probiotics, lutein, eicosapentaenoic acid/docosahexaenoic acid oils, single vitamins, and propolis. The results show that women have a higher probability of consuming these products than men. However, younger consumers are more likely to take multivitamins and probiotics, while older consumers are more likely to consume lutein, eicosapentaenoic acid/docosahexaenoic acid oils, and propolis products. For most products, a higher income level increases the probability of taking them. On the other hand, the national health expenditure saved due to consumers' intake of health functional foods is estimated to be approximately 8.952 trillion won (about USD 8 billion), which includes about 2.202 trillion won (about USD 1.95 billion) in the private sector and approximately 6.750 trillion won (about USD 5.98 billion) in the public sector.","PeriodicalId":12362,"journal":{"name":"Food Supplements and Biomaterials for Health","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91526334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Noh, B. Jeon, Seungah Lee, Jaeho Myeong, Ga-young Kim, Jiwon Lee, Sungsu Kim, Junkee Hong
Toscano ( Brassica oleracea L. var. acephala ) and Ussuri thistle ( Cirsium japonicum var. maackii (Maxim.) Matsum.) are known to have a beneficial effect on the liver function possibly through antioxidant action. In the present study, the combined extract of both of the plants, named TOSCARE™ was prepared and its beneficial effect was tested by observing its effects on cytotoxicity induced by oxidative stress and chemical, and hepatotoxicity induced by heavy metals. TOSCARE™ inhibited the cell death of HepG2 cells by treatment with H 2 O 2 and also with Tacrine known to generating reactive oxygen species (ROS). In the same experiment, TOSCARE™ was observed to remove ROS and inhibit the increase of expression of cytochrome P450 1A1 and suppressed the decrease of expression of Bcl-2 and ERK. TOSCARE™ also showed the preventive effect on hepatotoxicity induced by heavy metals (Pb, Cd) in rats, which was supported by the blood chemistry data: aspartate aminotransferase from 301 ± 64.20 to 197.9 ± 21.95 U/L ( P < 0.05), lactate dehydrogenase from 313.00 ± 61.73 to 174.18 ± 21.76 U/L ( P < 0.05), and blood urea nitrogen from 27.78 ± 2.18 mg/ to 18.95 ± 0.74 mg/dL ( P < 0.05). The results obtained suggest that TOSCARE™ can have beneficial effect on cell and organ damages induced by ROS, chemicals and heavy metals. damage. Various methods are being tried to prevent the impairment of liver function. In Korea, various biomaterials have been studied for this purpose.
托斯卡纳(Brassica oleracea L. var. acephala)和乌苏里蓟(Cirsium japonicum var. maackii))可能通过抗氧化作用对肝功能有有益的影响。本研究制备了两种植物的联合提取物TOSCARE™，并通过观察其对氧化应激和化学诱导的细胞毒性以及重金属诱导的肝毒性的影响来验证其有益作用。TOSCARE™通过h2o2和已知产生活性氧(ROS)的Tacrine处理抑制HepG2细胞的细胞死亡。在同一实验中，观察到TOSCARE™去除ROS，抑制细胞色素P450 1A1表达的增加，抑制Bcl-2和ERK表达的下降。TOSCARE™对大鼠重金属(Pb、Cd)肝毒性的预防作用也得到了血液化学数据的支持:天冬氨酸转氨酶从301±64.20 ~ 197.9±21.95 U/L (P < 0.05)，乳酸脱氢酶从313.00±61.73 ~ 174.18±21.76 U/L (P < 0.05)，尿素氮从27.78±2.18 mg/ L ~ 18.95±0.74 mg/dL (P < 0.05)。结果表明，TOSCARE™对活性氧、化学物质和重金属引起的细胞和器官损伤具有有益作用。损害。人们正在尝试各种方法来防止肝功能受损。在韩国，为此研究了各种生物材料。
{"title":"The Protective Effect of TOSCARE™ on Toxic Actions by Reactive Oxygen Species, Chemical and Heavy Metals","authors":"Y. Noh, B. Jeon, Seungah Lee, Jaeho Myeong, Ga-young Kim, Jiwon Lee, Sungsu Kim, Junkee Hong","doi":"10.52361/FSBH.2021.1.E6","DOIUrl":"https://doi.org/10.52361/FSBH.2021.1.E6","url":null,"abstract":"Toscano ( Brassica oleracea L. var. acephala ) and Ussuri thistle ( Cirsium japonicum var. maackii (Maxim.) Matsum.) are known to have a beneficial effect on the liver function possibly through antioxidant action. In the present study, the combined extract of both of the plants, named TOSCARE™ was prepared and its beneficial effect was tested by observing its effects on cytotoxicity induced by oxidative stress and chemical, and hepatotoxicity induced by heavy metals. TOSCARE™ inhibited the cell death of HepG2 cells by treatment with H 2 O 2 and also with Tacrine known to generating reactive oxygen species (ROS). In the same experiment, TOSCARE™ was observed to remove ROS and inhibit the increase of expression of cytochrome P450 1A1 and suppressed the decrease of expression of Bcl-2 and ERK. TOSCARE™ also showed the preventive effect on hepatotoxicity induced by heavy metals (Pb, Cd) in rats, which was supported by the blood chemistry data: aspartate aminotransferase from 301 ± 64.20 to 197.9 ± 21.95 U/L ( P < 0.05), lactate dehydrogenase from 313.00 ± 61.73 to 174.18 ± 21.76 U/L ( P < 0.05), and blood urea nitrogen from 27.78 ± 2.18 mg/ to 18.95 ± 0.74 mg/dL ( P < 0.05). The results obtained suggest that TOSCARE™ can have beneficial effect on cell and organ damages induced by ROS, chemicals and heavy metals. damage. Various methods are being tried to prevent the impairment of liver function. In Korea, various biomaterials have been studied for this purpose.","PeriodicalId":12362,"journal":{"name":"Food Supplements and Biomaterials for Health","volume":"79 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81117902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hydrogen (H 2 ) has been the focus of industrial interest as a pollution-free fuel. In addition, hydrogen is also a hot topic in medicine. Recently, animal and human experiments have shown that hydrogen is effective in treating various diseases, raising the possibility of developing hydrogen as a new therapeutic agent. The therapeutic effect of hydrogen is due to its antioxidant action to remove reactive oxygen species (ROS) effectively. Currently, it is known that ROS is involved in almost all diseases that afflict mankind. The therapeutic effect of hydrogen was reported first by Ohsawa and colleagues in 2007. They induced brain injury in rats by ischemia-reperfusion and found that inhalation of hydrogen gas (2%) markedly suppressed brain injury by inhibiting the actions of ROS. Since then, many researchers have found that hydrogen was effective in the ROS-involved diseases (diabetes, kidney complication of renal dialysis, acute brain infarction, inflammatory diseases of skin, muscle and joint, side effects of radiotherapy, skin wrinkles and post-exercise fatigue) in animal models and patients. In particular, hydrogen gas, unlike conventional antioxidants, 1) easily passes through the cell membrane and thus, is easily distributed to all organs and tissues of our body, 2) uniquely removes the most toxic hydroxyl radicals (•OH) of ROS, and 3) has no adverse or toxic effects with doses (0.4 and 1.6 ppm) used in all experiments reported. Based on the results of these experiments, attempts to use hydrogen as a therapeutic are actively underway. Given the fact that ROS are constantly produced in our bodies, the use of hydrogen gas or hydrogenated water is thought to help maintain health through treatment or prevention of diseases. increase in SOD and decrease in TBARS (thiobarbituric acid reactive substance) in and increase in high-density lipoprotein (HDL)-cholesterol and decrease in total cholesterol/HDL-cholesterol in blood. These results suggest
{"title":"The Medical Uses of Hydrogen","authors":"M. Chung, J. Ro","doi":"10.52361/FSBH.2021.1.E5","DOIUrl":"https://doi.org/10.52361/FSBH.2021.1.E5","url":null,"abstract":"Hydrogen (H 2 ) has been the focus of industrial interest as a pollution-free fuel. In addition, hydrogen is also a hot topic in medicine. Recently, animal and human experiments have shown that hydrogen is effective in treating various diseases, raising the possibility of developing hydrogen as a new therapeutic agent. The therapeutic effect of hydrogen is due to its antioxidant action to remove reactive oxygen species (ROS) effectively. Currently, it is known that ROS is involved in almost all diseases that afflict mankind. The therapeutic effect of hydrogen was reported first by Ohsawa and colleagues in 2007. They induced brain injury in rats by ischemia-reperfusion and found that inhalation of hydrogen gas (2%) markedly suppressed brain injury by inhibiting the actions of ROS. Since then, many researchers have found that hydrogen was effective in the ROS-involved diseases (diabetes, kidney complication of renal dialysis, acute brain infarction, inflammatory diseases of skin, muscle and joint, side effects of radiotherapy, skin wrinkles and post-exercise fatigue) in animal models and patients. In particular, hydrogen gas, unlike conventional antioxidants, 1) easily passes through the cell membrane and thus, is easily distributed to all organs and tissues of our body, 2) uniquely removes the most toxic hydroxyl radicals (•OH) of ROS, and 3) has no adverse or toxic effects with doses (0.4 and 1.6 ppm) used in all experiments reported. Based on the results of these experiments, attempts to use hydrogen as a therapeutic are actively underway. Given the fact that ROS are constantly produced in our bodies, the use of hydrogen gas or hydrogenated water is thought to help maintain health through treatment or prevention of diseases. increase in SOD and decrease in TBARS (thiobarbituric acid reactive substance) in and increase in high-density lipoprotein (HDL)-cholesterol and decrease in total cholesterol/HDL-cholesterol in blood. These results suggest","PeriodicalId":12362,"journal":{"name":"Food Supplements and Biomaterials for Health","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82158852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.52361/fsbh.2021.1.e37
Hayoung Kim, Seung A Chae, Minjee Lee, S. Yang, O-Hyun Ban, Y. Jung, Jungwoo Yang
{"title":"Genomic and Toxicity Studies on Bifidobacterium longum IDCC 4101 and Bifidobacterium bifidum IDCC 4201 Isolated from Feces of Breast-Fed Infants","authors":"Hayoung Kim, Seung A Chae, Minjee Lee, S. Yang, O-Hyun Ban, Y. Jung, Jungwoo Yang","doi":"10.52361/fsbh.2021.1.e37","DOIUrl":"https://doi.org/10.52361/fsbh.2021.1.e37","url":null,"abstract":"","PeriodicalId":12362,"journal":{"name":"Food Supplements and Biomaterials for Health","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79189895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.52361/fsbh.2021.1.e38
K. Ko
{"title":"We Are Not Informed Enough","authors":"K. Ko","doi":"10.52361/fsbh.2021.1.e38","DOIUrl":"https://doi.org/10.52361/fsbh.2021.1.e38","url":null,"abstract":"","PeriodicalId":12362,"journal":{"name":"Food Supplements and Biomaterials for Health","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78475838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.52361/fsbh.2021.1.e40
G. Hong, E. Hong, M. Chung, J. Ro
{"title":"Hwang Chan Go, a Mixture of Onion, Garlic and Wild Rice Extracts, Reduces the Release of Mediators from Mast Cell in Ovalbumin-Induced Allergic Lung in Mice","authors":"G. Hong, E. Hong, M. Chung, J. Ro","doi":"10.52361/fsbh.2021.1.e40","DOIUrl":"https://doi.org/10.52361/fsbh.2021.1.e40","url":null,"abstract":"","PeriodicalId":12362,"journal":{"name":"Food Supplements and Biomaterials for Health","volume":"103 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77615692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.52361/FSBH.2021.1.E10
Nam-Cheol Kim
Medicines from natural products have been used throughout human history. Because of growing interest, traditional medicine-based herbal medicines and botanical dietary supplements are popular among consumers. However, due to insufficient quality of many products, safety and efficacy are challenges from the modern medicine's point of view. This is particularly important at the global level because increased international commerce without the evidence of quality at global level makes consumers more prone to being exposed to low quality products. Efforts to ensure the quality of botanical products need the support of global public standards, and their proper use for quality assessments is also highly important. Differences in regulatory status among countries prompted the need for quality standards to include appropriate test methods and specifications. Pharmacopeial monographs define the specifications which herbal products need to show proper quality. Because of the complexity of the botanical materials, building quality standards in pharmacopeias needs careful consideration to include proper methods for identity, purity and strength, as well as appropriate acceptance criteria.
{"title":"Need for Pharmacopeial Quality Standards for Botanical Dietary Supplements and Herbal Medicines","authors":"Nam-Cheol Kim","doi":"10.52361/FSBH.2021.1.E10","DOIUrl":"https://doi.org/10.52361/FSBH.2021.1.E10","url":null,"abstract":"Medicines from natural products have been used throughout human history. Because of growing interest, traditional medicine-based herbal medicines and botanical dietary supplements are popular among consumers. However, due to insufficient quality of many products, safety and efficacy are challenges from the modern medicine's point of view. This is particularly important at the global level because increased international commerce without the evidence of quality at global level makes consumers more prone to being exposed to low quality products. Efforts to ensure the quality of botanical products need the support of global public standards, and their proper use for quality assessments is also highly important. Differences in regulatory status among countries prompted the need for quality standards to include appropriate test methods and specifications. Pharmacopeial monographs define the specifications which herbal products need to show proper quality. Because of the complexity of the botanical materials, building quality standards in pharmacopeias needs careful consideration to include proper methods for identity, purity and strength, as well as appropriate acceptance criteria.","PeriodicalId":12362,"journal":{"name":"Food Supplements and Biomaterials for Health","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77419693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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