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Sustaining evidence-based practices in mental health: The role of the EPIS framework
IF 4.1 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-03-01 DOI: 10.1016/j.genhosppsych.2025.02.021
Monica Widyaswari , Ali Fakhrudin , Shobri Firman Susanto
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引用次数: 0
The effectiveness of immersive virtual reality on the psychology of older adults: A systematic review and Meta-analysis of randomized controlled trials
IF 4.1 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-02-28 DOI: 10.1016/j.genhosppsych.2025.02.024
Zhilan Ke , Meng Wei , Fen Yang , Yufei Qiu , Xinhong Zhu , Xiaolian Gao , Jing Zhou , Guiyuan Qiao

Background

The increasing prevalence of psychological issues among older adults is a significant public health concern. Immersive Virtual Reality (IVR) is being investigated and tested as a potential intervention tool for addressing these issues.

Objective

This review aims to assess the effectiveness of IVR devices in enhancing the psychological well-being of older adults.

Methods

A comprehensive literature search was conducted across the PubMed, EMBASE, Web of Science, and Cochrane Library databases up to January 24, 2024. The Cochrane Risk of Bias Tool for Randomized Trials, version 2, was used to assess the methodological quality of the studies and determine the levels of evidence for the outcomes. Results are reported as Standardized Mean Differences (SMDs) with 95 % Confidence Intervals (CIs).

Results

The primary outcomes of this review were depression and anxiety, with psychological well-being as the secondary outcome. Among the 15 randomized controlled trials (RCTs) included (n = 15), for overall methodological quality, 1 study showed high risk, 6 studies showed some concerns and 8 studies showed low risk. A total of 802 older adults participated across the studies. Compared with control groups, IVR intervention was more effective in reducing depression (SMD -0.608, 95 % CI -0.900 ∼ −0.315, P < 0.001), anxiety (SMD -0.708, 95 % CI -1.119 ∼ −0.297, P = 0.001), and more effective in improving psychological well-being (SMD 0.641, 95 % CI 0.068–1.214, P = 0.028).

Conclusions

IVR has the potential to improve the psychological health of older adults and may be widely applicable in promoting successful aging.
{"title":"The effectiveness of immersive virtual reality on the psychology of older adults: A systematic review and Meta-analysis of randomized controlled trials","authors":"Zhilan Ke ,&nbsp;Meng Wei ,&nbsp;Fen Yang ,&nbsp;Yufei Qiu ,&nbsp;Xinhong Zhu ,&nbsp;Xiaolian Gao ,&nbsp;Jing Zhou ,&nbsp;Guiyuan Qiao","doi":"10.1016/j.genhosppsych.2025.02.024","DOIUrl":"10.1016/j.genhosppsych.2025.02.024","url":null,"abstract":"<div><h3>Background</h3><div>The increasing prevalence of psychological issues among older adults is a significant public health concern. Immersive Virtual Reality (IVR) is being investigated and tested as a potential intervention tool for addressing these issues.</div></div><div><h3>Objective</h3><div>This review aims to assess the effectiveness of IVR devices in enhancing the psychological well-being of older adults.</div></div><div><h3>Methods</h3><div>A comprehensive literature search was conducted across the PubMed, EMBASE, Web of Science, and Cochrane Library databases up to January 24, 2024. The Cochrane Risk of Bias Tool for Randomized Trials, version 2, was used to assess the methodological quality of the studies and determine the levels of evidence for the outcomes. Results are reported as Standardized Mean Differences (SMDs) with 95 % Confidence Intervals (CIs).</div></div><div><h3>Results</h3><div>The primary outcomes of this review were depression and anxiety, with psychological well-being as the secondary outcome. Among the 15 randomized controlled trials (RCTs) included (<em>n</em> = 15), for overall methodological quality, 1 study showed high risk, 6 studies showed some concerns and 8 studies showed low risk. A total of 802 older adults participated across the studies. Compared with control groups, IVR intervention was more effective in reducing depression (SMD -0.608, 95 % CI -0.900 ∼ −0.315, <em>P</em> &lt; 0.001), anxiety (SMD -0.708, 95 % CI -1.119 ∼ −0.297, <em>P</em> = 0.001), and more effective in improving psychological well-being (SMD 0.641, 95 % CI 0.068–1.214, <em>P</em> = 0.028).</div></div><div><h3>Conclusions</h3><div>IVR has the potential to improve the psychological health of older adults and may be widely applicable in promoting successful aging.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"94 ","pages":"Pages 86-96"},"PeriodicalIF":4.1,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143534184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Large-scale validation of the Kessler-10 Scale's psychometric properties among healthcare professionals in China
IF 4.1 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-02-26 DOI: 10.1016/j.genhosppsych.2025.02.017
Ye Wang , Zheng Zeng , Changqun Huang , Jing Ma , Jialu Ye , Jiafeng Li , Xiuliang Deng , Lan Zhang

Objectives

The Kessler Psychological Distress Scale (K10) is a 10-item questionnaire designed to measure psychological distress. The present study aimed to validate the factor structure of the K10 and its reliability and validity using a large sample from healthcare professionals in China mainland.

Methods

K10 data were collected in September 19 to October 20, 2023 via anonymous online survey (total sample, N = 8602).
The internal consistency reliability of the K10 was examined. Exploratory factor analysis (N = 4301) and confirmatory factor analysis(N = 4301) were conducted to validate the structural validity.

Results

Exploratory factor analysis revealed two factors, depression (DEP) and anxiety (ANX), which together accounted for 75.91 % of the total variance. Confirmatory factor analysis further supported the two-factor oblique model as the best fit, outperforming the one-factor model. The internal consistency of the K10 was α = 0.952, while the internal consistency coefficients for ANX and DEP were 0.883 and 0.940, respectively.

Conclusions

K10 is a validated and concise tool that serves a dual purpose of screening psychological distress and assessing depressive and anxiety symptoms among healthcare professionals in China.
{"title":"Large-scale validation of the Kessler-10 Scale's psychometric properties among healthcare professionals in China","authors":"Ye Wang ,&nbsp;Zheng Zeng ,&nbsp;Changqun Huang ,&nbsp;Jing Ma ,&nbsp;Jialu Ye ,&nbsp;Jiafeng Li ,&nbsp;Xiuliang Deng ,&nbsp;Lan Zhang","doi":"10.1016/j.genhosppsych.2025.02.017","DOIUrl":"10.1016/j.genhosppsych.2025.02.017","url":null,"abstract":"<div><h3>Objectives</h3><div>The Kessler Psychological Distress Scale (K10) is a 10-item questionnaire designed to measure psychological distress. The present study aimed to validate the factor structure of the K10 and its reliability and validity using a large sample from healthcare professionals in China mainland.</div></div><div><h3>Methods</h3><div>K10 data were collected in September 19 to October 20, 2023 via anonymous online survey (total sample, <em>N</em> = 8602).</div><div>The internal consistency reliability of the K10 was examined. Exploratory factor analysis (<em>N</em> = 4301) and confirmatory factor analysis(N = 4301) were conducted to validate the structural validity.</div></div><div><h3>Results</h3><div>Exploratory factor analysis revealed two factors, depression (DEP) and anxiety (ANX), which together accounted for 75.91 % of the total variance. Confirmatory factor analysis further supported the two-factor oblique model as the best fit, outperforming the one-factor model. The internal consistency of the K10 was α = 0.952, while the internal consistency coefficients for ANX and DEP were 0.883 and 0.940, respectively.</div></div><div><h3>Conclusions</h3><div>K10 is a validated and concise tool that serves a dual purpose of screening psychological distress and assessing depressive and anxiety symptoms among healthcare professionals in China.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"94 ","pages":"Pages 112-117"},"PeriodicalIF":4.1,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143551377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Targeted beta-blocker use in moderate cardiac anxiety: Implications from recent findings
IF 4.1 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-02-25 DOI: 10.1016/j.genhosppsych.2025.02.019
Rikas Saputra , Yenni Lidyawati
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引用次数: 0
DCARD checklist: A simple screening tool for Lewy body disease-related early symptoms in memory clinic
IF 4.1 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-02-21 DOI: 10.1016/j.genhosppsych.2025.02.011
Koji Kasanuki , Moto Nishiguchi , Mikiko Hagiwara , Motoyuki Higa , Shuntaro Natsume , Takao Saida , Noemi Endo , Hideki Sugiyama , Kiyoshi Sato

Objective

Despite the relatively high prevalence of Lewy body disease (LBD) in over middle-aged people, physicians and patients show poor awareness of early symptoms. We examined the clinical utility of a simple checklist for screening for the early symptoms of LBD.

Methods

We administered a 7-item screening checklist assessing the five representative early symptoms of LBD (dizziness, constipation, anosmia, REM sleep behavior disorder, and depression: the acronym is “DCARD”) to 450 consecutive individuals who visited the memory clinic at our university hospital. The aim of this retrospective study was to evaluate the usefulness of the DCARD checklist in differentiating neurocognitive disorders (NCD) due to LBD (i.e., NCD with Lewy bodies and NCD due to Parkinson's disease) from NCD due to non-LBD (e.g., Alzheimer's disease). We also associated the DCARD score with current depressive symptoms using the 15-item Geriatric Depression Scale (GDS-15).

Results

Fifty-five participants (12.2 %) had a higher DCARD score (≥4 out of 7 points) regardless of the global cognitive level. The subgroup with higher DCARD scores had higher GDS-15 scores than the subgroup with lower DCARD scores (p < 0.001). With a DCARD cut-off score of 3/4, the sensitivity and specificity were 65 % and 95 %, respectively, for diagnosing NCD due to LBDs. Receiver operating characteristic curve analysis showed good discriminatory ability (area under the curve: 0.89).

Conclusions

This simple LBD screening checklist may be useful as a diagnostic tool for the early diagnosis of LBD in memory clinics.
Clinical trial registry: None.
尽管路易体病(LBD)在中年以上人群中的发病率相对较高,但医生和患者对其早期症状却知之甚少。方法我们对在本大学医院记忆门诊就诊的 450 名连续就诊者进行了 7 个项目的筛查,评估了路易体病的五个代表性早期症状(头晕、便秘、嗅觉障碍、快速眼动睡眠行为障碍和抑郁:缩写为 "DCARD")。这项回顾性研究旨在评估 DCARD 检查表在区分枸杞多糖所致神经认知障碍(NCD)(即路易体 NCD 和帕金森病 NCD)与非枸杞多糖所致神经认知障碍(NCD)(如阿尔茨海默病)方面的实用性。我们还使用 15 项老年抑郁量表(GDS-15)将 DCARD 评分与当前的抑郁症状联系起来。结果55 名参与者(12.2%)的 DCARD 评分较高(≥4 分,满分为 7 分),与总体认知水平无关。DCARD得分较高的亚组的GDS-15得分高于DCARD得分较低的亚组(p < 0.001)。当 DCARD 临界分数为 3/4 时,诊断枸杞多糖引起的 NCD 的灵敏度和特异度分别为 65 % 和 95 %。结论这份简单的枸杞多糖筛查核对表可作为记忆诊所早期诊断枸杞多糖的诊断工具:临床试验登记:无。
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引用次数: 0
Depressive symptoms and risk of all-cause mortality among middle-aged and older populations with and without prediabetes in China
IF 4.1 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-02-20 DOI: 10.1016/j.genhosppsych.2025.02.014
Jing Hu , Lin Zhuo , Jiaxin Zuo , Tiantian Zhou , Feifei Lin , Houyu Zhao , Chen Zhang , Weiwei Wang , Gang Wang , Lei Feng

Background

Although depressive symptoms have been associated with increased mortality risk in diabetes patients, the potential implications for individuals with prediabetes remain underexplored. This study aimed to investigate the association between depressive symptoms and all-cause mortality and to determine whether these associations differ between individuals with and without prediabetes in middle-aged and older Chinese adults.

Methods

This is a cohort study from the 2011–2020 China Health and Retirement Longitudinal Study (CHARLS). Depressive symptoms were assessed by the 10-item Center for Epidemiologic Studies Depression Scale (CES-D-10). All-cause mortality was documented from the baseline through the end of follow-up in 2020. Cox proportional hazards regression was used to evaluate the association of depressive symptoms with all-cause mortality among adults with and without prediabetes, adjusting for potential confounders.

Results

After multivariable adjustments, depressive symptoms were associated with a higher risk of all-cause mortality (HR, 1.40; 95 % CI: 1.16–1.68) for those with prediabetes, participants with moderate depressive symptoms exhibited an HR of 1.36 (95 %CI, 1.13–1.65), while those with severe depressive symptoms had an HR of 1.62 (95 %CI, 1.13–2.32) compared to those without depressive symptoms (P for trend <0.001). However, among individuals without prediabetes, depressive symptoms didn't increase the risk of all-cause mortality.

Conclusions

Elevated depressive symptoms are significantly associated with an increased risk of all-cause mortality among populations with prediabetes, the risk of death increased with the severity of depressive symptoms. Our findings suggest that careful monitoring and intervention in individuals with both prediabetes and depressive symptoms is needed.
背景虽然抑郁症状与糖尿病患者死亡风险的增加有关,但其对糖尿病前期患者的潜在影响仍未得到充分探讨。本研究旨在调查抑郁症状与全因死亡率之间的关系,并确定这些关系在中国中老年人中患有糖尿病前期和未患有糖尿病前期的个体之间是否存在差异。抑郁症状通过10项流行病学研究中心抑郁量表(CES-D-10)进行评估。记录了从基线到 2020 年随访结束期间的全因死亡率。结果经多变量调整后,抑郁症状与较高的全因死亡风险相关(HR,1.与无抑郁症状的人相比,有中度抑郁症状的人的 HR 为 1.36(95 %CI,1.13-1.65),而有重度抑郁症状的人的 HR 为 1.62(95 %CI,1.13-2.32)(趋势 P 为 0.001)。结论在糖尿病前期人群中,抑郁症状的加重与全因死亡风险的增加有显著相关性,死亡风险随抑郁症状的严重程度而增加。我们的研究结果表明,需要对同时患有糖尿病前期和抑郁症状的人群进行仔细监测和干预。
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引用次数: 0
Identifying anti-LGI-1 encephalitis in psychotic disorders: A clinically focused review
IF 4.1 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-02-20 DOI: 10.1016/j.genhosppsych.2025.02.016
Yujie Yi , Yingzhu Zhao , Hong Zhou, Jie Wang

Introduction

Anti-LGI-1 limbic encephalitis, the second most common autoimmune encephalitis, typically presents with psychotic symptoms. However, systematic characterization of psychotic features in this disease remains scarce, with insufficient granularity in existing symptom descriptions. This systematic review aims to characterize the psychotic manifestations in anti-LGI-1 encephalitis through a comprehensive analysis of published cases and institutional data.

Methods

Following PRISMA guidelines, we systematically searched PubMed, Embase, and Web of Science for case reports of anti-LGI-1 encephalitis, specifically focusing on cases with confirmed diagnoses and psychotic symptoms. Additionally, clinical data from patients diagnosed with anti-LGI-1 encephalitis and admitted to Shanxi Medical University First Hospital between January 2018 and June 2024 who also exhibited psychotic symptoms were collected. The data were then classified and statistically analyzed to assess patient characteristics.

Results

31articles and 24 clinical cases were found, leading to 74 cases that met the inclusion criteria. Among these, 59.46 % of patients showed initial psychotic symptoms during their illness. Common positive symptoms included hallucinations, delusions, and delirium presenting with disorganized speech, while negative symptoms often involved apathy/indifference, depression, and catatonia-related physical issues. Sleep disturbances were also common.

Conclusion

When a patient presents with an unexplained alteration in mental status, the potential diagnosis of anti-LGI-1 encephalitis must be considered. This consideration facilitates timely and accurate diagnosis for patients suffering from anti-LGI-1 encephalitis, ultimately enhancing their prognosis.
{"title":"Identifying anti-LGI-1 encephalitis in psychotic disorders: A clinically focused review","authors":"Yujie Yi ,&nbsp;Yingzhu Zhao ,&nbsp;Hong Zhou,&nbsp;Jie Wang","doi":"10.1016/j.genhosppsych.2025.02.016","DOIUrl":"10.1016/j.genhosppsych.2025.02.016","url":null,"abstract":"<div><h3>Introduction</h3><div>Anti-LGI-1 limbic encephalitis, the second most common autoimmune encephalitis, typically presents with psychotic symptoms. However, systematic characterization of psychotic features in this disease remains scarce, with insufficient granularity in existing symptom descriptions. This systematic review aims to characterize the psychotic manifestations in anti-LGI-1 encephalitis through a comprehensive analysis of published cases and institutional data.</div></div><div><h3>Methods</h3><div>Following PRISMA guidelines, we systematically searched PubMed, Embase, and Web of Science for case reports of anti-LGI-1 encephalitis, specifically focusing on cases with confirmed diagnoses and psychotic symptoms. Additionally, clinical data from patients diagnosed with anti-LGI-1 encephalitis and admitted to Shanxi Medical University First Hospital between January 2018 and June 2024 who also exhibited psychotic symptoms were collected. The data were then classified and statistically analyzed to assess patient characteristics.</div></div><div><h3>Results</h3><div>31articles and 24 clinical cases were found, leading to 74 cases that met the inclusion criteria. Among these, 59.46 % of patients showed initial psychotic symptoms during their illness. Common positive symptoms included hallucinations, delusions, and delirium presenting with disorganized speech, while negative symptoms often involved apathy/indifference, depression, and catatonia-related physical issues. Sleep disturbances were also common.</div></div><div><h3>Conclusion</h3><div>When a patient presents with an unexplained alteration in mental status, the potential diagnosis of anti-LGI-1 encephalitis must be considered. This consideration facilitates timely and accurate diagnosis for patients suffering from anti-LGI-1 encephalitis, ultimately enhancing their prognosis.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"94 ","pages":"Pages 74-83"},"PeriodicalIF":4.1,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143508948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cognitive, symptomatic, and pharmacological factors contributing to objective social functioning improvement in schizophrenia rehabilitation: A prospective study
IF 4.1 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-02-19 DOI: 10.1016/j.genhosppsych.2025.02.015
Xin Zhao , Xue Yang , Wen Wang , Wei Jiang , Wen-qing Jin , Yi-lang Tang , Cun-li Xiao , Yan-ping Ren
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引用次数: 0
E-Cigarettes and Mental Health: A Critical Examination of Their Role in Smoking Cessation Programs
IF 4.1 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-02-17 DOI: 10.1016/j.genhosppsych.2025.02.013
Fiki Prayogi , Palasara Brahmani Laras , Hendra Pribadi , Mareyke Jessy Tanod , Prio Utomo
{"title":"E-Cigarettes and Mental Health: A Critical Examination of Their Role in Smoking Cessation Programs","authors":"Fiki Prayogi ,&nbsp;Palasara Brahmani Laras ,&nbsp;Hendra Pribadi ,&nbsp;Mareyke Jessy Tanod ,&nbsp;Prio Utomo","doi":"10.1016/j.genhosppsych.2025.02.013","DOIUrl":"10.1016/j.genhosppsych.2025.02.013","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"94 ","pages":"Pages 35-36"},"PeriodicalIF":4.1,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143464699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sex-based cardiovascular risk in depressive symptoms
IF 4.1 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-02-17 DOI: 10.1016/j.genhosppsych.2025.02.012
Agung Yuliyanto Nugroho , Lastiani Warih Wulandari , Damiasih Damiasih , Herra Herryani , Aldora Pratama , Rikas Saputra , Erfan Ramadhani , Yenni Lidyawati
{"title":"Sex-based cardiovascular risk in depressive symptoms","authors":"Agung Yuliyanto Nugroho ,&nbsp;Lastiani Warih Wulandari ,&nbsp;Damiasih Damiasih ,&nbsp;Herra Herryani ,&nbsp;Aldora Pratama ,&nbsp;Rikas Saputra ,&nbsp;Erfan Ramadhani ,&nbsp;Yenni Lidyawati","doi":"10.1016/j.genhosppsych.2025.02.012","DOIUrl":"10.1016/j.genhosppsych.2025.02.012","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"94 ","pages":"Pages 33-34"},"PeriodicalIF":4.1,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143445214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
General hospital psychiatry
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