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Cytokine Response of CD4+ T-Lymphocytes with Red Rose (Rosa Rosaceae – Pierre de Ronsard) Extracts by in Vitro Evaluation 红玫瑰提取物对CD4+ t淋巴细胞细胞因子反应的体外评价
IF 0.1 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-03-01 DOI: 10.21802/gmj.2022.1.5
M. Arokiaraj, E. Menesson
Background. Red rose extract is known to have anti-inflammatory and immune-modulation effects. In this study, the red rose extract was tested on CD4+T lymphocytes in vitro, and cytokine response was evaluated. Materials and Methods. The red rose (Rosa Rosaceae - Pierre de Ronsard) extract used in this study was prepared and stored at -20° C until use. CD4+T-cells were seeded in 96-well plates at 313,500 cells/well in 100μ l cell culture medium in duplicate. One-half of the wells were used for biomarker screening in the culture medium, and the other half was used for cytotoxicity assay. Twenty-four hours after plating, the cells were treated in duplicate with 100μ l of the red rose extract diluted at 0.5%, 0.1%, 0.05%, 0.01% and 0.005% (v/v) in the cell culture medium or with culture medium only as control for 72 hours. Some other wells were allocated for untreated cells, and cells treated with the rose extract at 0.005% for 48-h incubation time. Results. Several cytokines (GRO; IFN-γ; IL-1α, 6, 10; MCP-1; RANTES; TGF-β1; TIMP 1, 2; Ang1, Ang2; G-CSF; MMP-9; and VEGF R2) were elevated. Except for MMP-9, which had fold changes > 2, other cytokines were minimally elevated at various concentrations and timing of rose extract treatment. None of the mentioned cytokines were less than 0.8-fold after treatment with the rose extract. Cytotoxicity assay revealed insignificant changes in the viability of T-cells. Conclusions. There was a mild elevation in few inflammatory markers by CD4+ T-lymphocytes after in vitro treatment with the red rose extract (Rosa Rosacea - Pierre De Ronsard). Further in vitro and in vivo studies are required to evaluate the benefits of the red rose extract in immune regulation.
背景。众所周知,红玫瑰提取物具有抗炎和免疫调节作用。本研究通过体外检测红玫瑰提取物对CD4+T淋巴细胞的影响,并评价其对细胞因子的反应。材料与方法。制备本研究使用的红玫瑰(Rosa Rosaceae - Pierre de Ronsard)提取物,-20°C保存至使用。CD4+ t细胞在100μ l细胞培养基中以313,500个细胞/孔接种于96孔板中,一式两份。一半孔用于培养基中生物标志物筛选,另一半孔用于细胞毒性测定。24小时后,分别用100μ l按0.5%、0.1%、0.05%、0.01%、0.005% (v/v)稀释的红玫瑰提取物在细胞培养基中或仅用培养基作为对照处理72小时。另外一些孔分配给未处理的细胞,用0.005%的玫瑰提取物处理细胞,孵育48小时。结果。几种细胞因子(GRO;干扰素-γ;Il-1α, 6,10;MCP-1;咆哮;转化生长因子-β1;时间1,2;Ang1 Ang2;g - csf;MMP-9;VEGF R2)升高。除MMP-9外,其他细胞因子在玫瑰提取物处理的不同浓度和时间下均有轻微升高。用玫瑰提取物处理后,上述细胞因子均不低于0.8倍。细胞毒性试验显示t细胞活力无明显变化。结论。红玫瑰提取物(Rosa Rosacea - Pierre De Ronsard)体外处理后,CD4+ t淋巴细胞中少数炎症标志物轻度升高。需要进一步的体外和体内研究来评估红玫瑰提取物在免疫调节中的益处。
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引用次数: 0
Nursing Care Satisfaction among Patients Infected with Covid-19: A Turkish Perspective 2019冠状病毒病患者护理满意度:土耳其视角
IF 0.1 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-03-01 DOI: 10.21802/gmj.2022.1.3
Handenur Gündoğdu, F. Tanrıkulu, F. Erol, Ferhat Koç, D. Yılmaz, Y. Dikmen
The aim of this study was to determine the satisfaction with nursing care among patients diagnosed with Covid-19 and related factors. Materials and Methods. The study was conducted between June and July 2020. The population of the study consisted of 102 patients treated in the Covid-19 clinics of the University Teaching and Research Hospital. The data were collected using the Newcastle Satisfaction with Nursing Care Scale with a total of 19 items, and the Patient Description Form designed to record the sociodemographic characteristics and medical histories. The data were evaluated using the program package IBM SPSS 20.0. To test the significance of the difference between two independent groups, the Student’s t-test was used, and the one-way ANOVA was used to test the significance of the difference between more than two groups. Results. The results showed that most patients were satisfied with nursing care. A higher level of satisfaction was seen in patients treated in the Covid-19 intensive care units, those with chronic conditions, and those who received information about their health state from nurses. Patients’ family type, sharing fears and worries with nurses, getting information from nurses and the quality of nursing care were the variables significantly associated with patient satisfaction with nursing care. Conclusions. Satisfaction with nursing care among Covid-19 patients was moderate. When nurses use effective communication skills to meet patients’ care needs, provide patients with adequate information, allow them to express their feelings, and keep them safe, this will further enhance patient satisfaction.
本研究旨在了解新冠肺炎患者的护理满意度及其相关因素。材料与方法。该研究于2020年6月至7月进行。该研究的人群包括102名在大学教研医院Covid-19诊所接受治疗的患者。数据采用纽卡斯尔护理满意度量表(共19项)和患者描述表(记录社会人口学特征和病史)收集。使用IBM SPSS 20.0软件包对数据进行评估。为了检验两个独立组之间差异的显著性,采用学生t检验,并采用单因素方差分析来检验两个以上组之间差异的显著性。结果。结果表明,大部分患者对护理满意。在Covid-19重症监护病房接受治疗的患者、慢性病患者以及从护士那里获得健康状况信息的患者的满意度更高。患者家庭类型、与护士分享恐惧和担忧、从护士处获取信息和护理质量是影响患者护理满意度的显著变量。结论。新冠肺炎患者对护理的满意度一般。当护士运用有效的沟通技巧来满足患者的护理需求,为患者提供足够的信息,允许患者表达自己的感受,并保证患者的安全,这将进一步提高患者的满意度。
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引用次数: 3
Diagnostic Accuracy of MR Mammography in Comparison with Digital Mammography and Sonomammography MR乳腺摄影与数字乳腺摄影和超声乳腺摄影的诊断准确性比较
IF 0.1 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-03-01 DOI: 10.21802/gmj.2022.1.4
Sreenidhi Sedguli, R. Gowda, Rupa Ranganathan, S. Kumar B.
Background. Even though the sensitivity of contrast-enhanced breast magnetic resonance mammography (CE-MRM) is consistently high in the range of 94-100%, conventionally, digital mammography and sonomammography continue as standard imaging modalities for the detection and evaluation of breast disease. The objective of the study was to detect additional lesions that go undetected by routine digital mammography and sonomammography using CE-MRM. Materials and Methods. In a prospective study, 68 patients who came for screening diagnostic mammogram and had breast lesions of Breast Imaging-Reporting and Data System category 3-6 were evaluated. All patients underwent bilateral digital mammography and targeted high-frequency sonomammography of the primary lesion. Those patients who were thought to possibly have breast cancer and to be candidates for surgical management were offered bilateral CE-MRM. Results. In this prospective study, we included 68 patients (mean age - 50.6 years, range - 30-73 years). A total of 74 lesions were evaluated. In detecting these lesions, digital mammography had a sensitivity of 40.0%, specificity of 100% and diagnostic accuracy of 63.5%. CE-MRM sensitivity was found to be 71.7%, specificity - 96.6% and diagnostic accuracy - 83.7%. Among the 27 additional lesions detected by CE-MRM, histopathological evaluation confirmed only 19, indicating the sensitivity of 100%, specificity of 85.4%, positive predictive value of 67.8%, negative predictive value of 100%, diagnostic accuracy of 89.2%. Conclusions. The diagnostic accuracy of CE-MRM was found to be 83.7%, with a specificity of 96.6%. CE-MRM detected 19 additional lesions that were undetected by either digital mammography or ultrasonography. CE-MRM is sensitive in detecting additional malignant lesions which are not detected by other imaging modalities.
背景尽管对比增强乳腺磁共振乳房X射线照相术(CE-MRM)的灵敏度一直很高,在94-100%的范围内,但传统上,数字乳腺X射线照相和超声乳腺X射线摄影仍然是检测和评估乳腺疾病的标准成像模式。该研究的目的是检测常规数字乳房X光摄影和使用CE-MRM的超声乳房X光照相未检测到的其他病变。材料和方法。在一项前瞻性研究中,对68名前来筛查诊断性乳房X光检查并患有乳腺成像报告和数据系统3-6类乳腺病变的患者进行了评估。所有患者均接受了双侧数字乳房X光摄影术和原发病变的靶向高频超声乳房X光照相术。那些被认为可能患有癌症并有望接受手术治疗的患者接受了双侧CE-MRM。后果在这项前瞻性研究中,我们纳入了68名患者(平均年龄-50.6岁,范围30-73岁)。共评估了74处病变。在检测这些病变时,数字乳腺摄影的敏感性为40.0%,特异性为100%,诊断准确率为63.5%。CE-MRM的敏感性为71.7%,特异性96.6%,诊断准确度83.7%。在CE-MRM检测到的27个额外病变中,组织病理学评估仅确认了19个,表明敏感性为100%,特异性85.4%,阳性预测值为67.8%,阴性预测值为100%,诊断准确率为89.2%。CE-MRM的诊断准确率为83.7%,特异性为96.6%。CE-MRM还检测到19个未经数字乳腺摄影或超声检查的病变。CE-MRM在检测其他成像方式未检测到的其他恶性病变方面是敏感的。
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引用次数: 1
Non-Alcoholic Fatty Liver Disease and Hypothyroidism: Review of Clinical and Experimental Studies 非酒精性脂肪肝与甲状腺功能减退的临床与实验研究综述
IF 0.1 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-12-01 DOI: 10.21802/gmj.2021.4.2
Tetiana Ranhulova
Hypothyroidism is a widespread condition affecting people of different socio-economic background and geographical location. A lot of studies highlight the effect of hypothyroidism on the metabolic processes in various organs, including the liver. On the other hand, liver damage often results in the development of non-alcoholic fatty liver disease; however, the data on the impact of hypothyroidism on liver morphology, which can serve as a direct indicator and marker of liver condition and function, are limited and controversial. In this report, we reviewed the relationship between non-alcoholic fatty liver disease and hypothyroidism with an accent on morphological alteration of the liver discovered in clinical and experimental studies.
甲状腺机能减退症是一种广泛的疾病,影响着不同社会经济背景和地理位置的人。许多研究强调甲状腺功能减退对包括肝脏在内的各种器官代谢过程的影响。另一方面,肝脏损伤往往导致非酒精性脂肪性肝病的发展;然而,作为肝脏状况和功能的直接指标和标志物,关于甲状腺功能减退对肝脏形态影响的数据是有限的,并且存在争议。在本报告中,我们回顾了非酒精性脂肪性肝病与甲状腺功能减退之间的关系,重点是在临床和实验研究中发现的肝脏形态学改变。
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引用次数: 1
Comparison of Preclinical Coursework Perception Among Dental Students from India and the Republic of North Macedonia 印度和北马其顿共和国牙科学生临床前课程认知的比较
IF 0.1 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-12-01 DOI: 10.21802/gmj.2021.4.6
M. Batra, V. Ambarkova, D. Gijwani, Hansika Popli, Natasa Stavreva, S. Apostolska, Niharika Narang, Tamanna Mutneja, Mira Jankulovska, K. Ivanovski
Background. The difference in the preclinical curriculum and teaching methodology between European and Southeast Asian countries has a great influence on the process of choosing which education model is predominant and, therefore, students’ opinion on the effectiveness of a preclinical coursework is diverse. The objective of the research was to assess the perception of the preclinical coursework in prosthodontics, conservative dentistry, and endodontics among Indian and North Macedonian students. Materials and Methods. This cross-sectional comparative study was carried out among 3rd-year students, final-year students and interns of dental schools of two respective countries. The data were collected in July 2021 using Google Form, a link to which was sent via available social media platforms. The data obtained were analyzed using SPSSv.21.0 (IBM) software. Results. The data on dental students’ perception of the preclinical coursework were obtained, analyzed, compared, and discussed. A total of 50% of Indian students stated preclinical exercises to be good to get knowledge about treating patients, whereas 47% of North Macedonian students felt the average level of knowledge needed for treating patient. Conclusions. In this study, the majority of the students were in favor of attending the preclinical course and understood its importance for building up their confidence, better understanding of the subject and better patient handling in future dental practice. However, there were different students’ opinions on the course content, its duration, exercises, faculty interaction, helpfulness of theory lectures that evidence essentiality to view dental studies from a student-centered perspective.
背景欧洲和东南亚国家在临床前课程和教学方法上的差异对选择哪种教育模式占主导地位的过程有很大影响,因此,学生对临床前课程的有效性的看法是多样的。该研究的目的是评估印度和北马其顿学生对口腔修复学、保守牙科和牙髓病临床前课程的看法。材料和方法。这项横断面比较研究是在两国牙科学校的三年级学生、大四学生和实习生中进行的。这些数据是在2021年7月使用谷歌表格收集的,该表格的链接通过可用的社交媒体平台发送。使用SPSSv.21.0(IBM)软件对所获得的数据进行分析。后果获得、分析、比较和讨论了牙科学生对临床前课程的感知数据。共有50%的印度学生表示,临床前锻炼有助于获得治疗患者的知识,而47%的北马其顿学生认为治疗患者所需的知识水平一般。结论。在这项研究中,大多数学生都赞成参加临床前课程,并理解该课程对建立信心、更好地理解该科目以及在未来牙科实践中更好地处理患者的重要性。然而,学生们对课程内容、持续时间、练习、教师互动、理论讲座的有用性有不同的看法,这证明了从以学生为中心的角度看待牙科研究的重要性。
{"title":"Comparison of Preclinical Coursework Perception Among Dental Students from India and the Republic of North Macedonia","authors":"M. Batra, V. Ambarkova, D. Gijwani, Hansika Popli, Natasa Stavreva, S. Apostolska, Niharika Narang, Tamanna Mutneja, Mira Jankulovska, K. Ivanovski","doi":"10.21802/gmj.2021.4.6","DOIUrl":"https://doi.org/10.21802/gmj.2021.4.6","url":null,"abstract":"Background. The difference in the preclinical curriculum and teaching methodology between European and Southeast Asian countries has a great influence on the process of choosing which education model is predominant and, therefore, students’ opinion on the effectiveness of a preclinical coursework is diverse. \u0000The objective of the research was to assess the perception of the preclinical coursework in prosthodontics, conservative dentistry, and endodontics among Indian and North Macedonian students. \u0000Materials and Methods. This cross-sectional comparative study was carried out among 3rd-year students, final-year students and interns of dental schools of two respective countries. The data were collected in July 2021 using Google Form, a link to which was sent via available social media platforms. The data obtained were analyzed using SPSSv.21.0 (IBM) software. \u0000Results. The data on dental students’ perception of the preclinical coursework were obtained, analyzed, compared, and discussed. A total of 50% of Indian students stated preclinical exercises to be good to get knowledge about treating patients, whereas 47% of North Macedonian students felt the average level of knowledge needed for treating patient. \u0000Conclusions. In this study, the majority of the students were in favor of attending the preclinical course and understood its importance for building up their confidence, better understanding of the subject and better patient handling in future dental practice. However, there were different students’ opinions on the course content, its duration, exercises, faculty interaction, helpfulness of theory lectures that evidence essentiality to view dental studies from a student-centered perspective.","PeriodicalId":12537,"journal":{"name":"Galician Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43694869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of Covid-19 Hospital Admissions in Ivano-Frankivsk, Ukraine 乌克兰伊万诺-弗兰基夫斯克新冠肺炎住院人数分析
IF 0.1 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-12-01 DOI: 10.21802/gmj.2021.4.1
O. Detsyk, Natalia Fedorkiv, O. Burak, Roksolana Kaluzhna
The Covid-19 pandemic has a substantial impact on socioeconomic, political, demographic, and other aspects of life. Effective healthcare is, however, a primary determinant of successful fighting against Covid-19. The analysis of local healthcare indicators serves as a source for estimating pandemic magnitude and the adaptation of healthcare at a national level. In this study, the rates of Covid-19 hospital admissions to the Ivano-Frankivsk City Hospital, Ukraine, from April 2020 to May 2021 were analysed. All cases were grouped by age, sex, and the type of admission; data were analyzed monthly and seasonally. The peaks of hospital admissions were observed in November 2020 and March 2021; however, the highest mortality rates were seen from August to November 2020. The analysis of age- and sex-disaggregated Covid-19 mortality data showed the predominance of elderly males (61.9%, 66.6 ± 3.9 years) over females (38.1%, 71.8 ± 2.3 years). The ratio of hospital admissions was unstable: the percentage of emergency, GP-referred and self-referred admissions was similar from April to May 2020; however, GP-referred admissions prevailed, and the number of self-referral patients decreased twice between March and May 2021. In conclusions, the trends in hospital admissions were similar to those reported in other studies. However, the differences in time frames and socio-demographic characteristics were observed that highlights the importance of considering regional, social and geographic aspects of the population when improving the capacity of healthcare system and establishing effective preventive measures against the pandemic at the local level.
新冠肺炎大流行对社会经济、政治、人口和生活的其他方面产生了重大影响。然而,有效的医疗保健是成功抗击新冠肺炎的主要决定因素。对当地医疗保健指标的分析是估计疫情规模和国家层面医疗保健适应情况的来源。在这项研究中,分析了2020年4月至2021年5月乌克兰伊万诺-弗兰基夫斯克市医院新冠肺炎住院率。所有病例均按年龄、性别和入院类型分组;数据按月和按季节进行分析。入院人数高峰出现在2020年11月和2021年3月;然而,2020年8月至11月的死亡率最高。对按年龄和性别划分的新冠肺炎死亡率数据的分析显示,老年男性(61.9%,66.6±3.9岁)高于女性(38.1%,71.8±2.3岁)。入院率不稳定:2020年4月至5月,急诊、全科医生转诊和自我转诊的入院率相似;然而,全科医生转诊入院占主导地位,自转诊患者人数在2021年3月至5月期间两次减少。总之,入院人数的趋势与其他研究报告的趋势相似。然而,观察到时间框架和社会人口特征的差异,这突出了在提高医疗保健系统的能力和在地方一级制定有效的疫情预防措施时,考虑人口的区域、社会和地理方面的重要性。
{"title":"Analysis of Covid-19 Hospital Admissions in Ivano-Frankivsk, Ukraine","authors":"O. Detsyk, Natalia Fedorkiv, O. Burak, Roksolana Kaluzhna","doi":"10.21802/gmj.2021.4.1","DOIUrl":"https://doi.org/10.21802/gmj.2021.4.1","url":null,"abstract":"The Covid-19 pandemic has a substantial impact on socioeconomic, political, demographic, and other aspects of life. Effective healthcare is, however, a primary determinant of successful fighting against Covid-19. The analysis of local healthcare indicators serves as a source for estimating pandemic magnitude and the adaptation of healthcare at a national level. In this study, the rates of Covid-19 hospital admissions to the Ivano-Frankivsk City Hospital, Ukraine, from April 2020 to May 2021 were analysed. All cases were grouped by age, sex, and the type of admission; data were analyzed monthly and seasonally. The peaks of hospital admissions were observed in November 2020 and March 2021; however, the highest mortality rates were seen from August to November 2020. The analysis of age- and sex-disaggregated Covid-19 mortality data showed the predominance of elderly males (61.9%, 66.6 ± 3.9 years) over females (38.1%, 71.8 ± 2.3 years). The ratio of hospital admissions was unstable: the percentage of emergency, GP-referred and self-referred admissions was similar from April to May 2020; however, GP-referred admissions prevailed, and the number of self-referral patients decreased twice between March and May 2021. In conclusions, the trends in hospital admissions were similar to those reported in other studies. However, the differences in time frames and socio-demographic characteristics were observed that highlights the importance of considering regional, social and geographic aspects of the population when improving the capacity of healthcare system and establishing effective preventive measures against the pandemic at the local level.","PeriodicalId":12537,"journal":{"name":"Galician Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41627129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monoarthritis of the Elbow Revealing Osteoid Osteoma: A Case Report and Literature Review 显露骨样骨瘤的肘关节单关节炎1例报告及文献复习
IF 0.1 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-12-01 DOI: 10.21802/gmj.2021.4.5
N. El Ouardi, S. Sadni, L. Taoubane, A. Mounach, A. Bezza
Osteoid osteoma is a rare benign osteoblastic tumor that mainly occurs in the extra-articular segments of lower limb long bones. The elbow is an exceptional location for osteoid osteoma. The diagnosis is usually delayed since the elbow is a rare site for this tumor and unspecific clinical signs, such monoarthritis, may mimic other more common conditions. We report the case of a 16-year-old girl who presented with chronic monoarthritis of the elbow which was treated falsely as tuberculous arthritis and monoarticular rheumatoid involvement. The laboratory tests were negative. Computed tomography scan and magnetic resonance imaging showed the focal nidus at the coronoid process of the ulna with mild synovitis. The diagnosis of osteoid osteoma was not made until the disease had been progressing for eighteen months and the elbow had already become stiff. Arthroscopic excision of the lesion was performed, and histopathology of the nidus was consistent with osteoid osteoma. Since then, the patient has been pain-free with an improved elbow range of motion.
骨样骨瘤是一种罕见的良性成骨细胞肿瘤,主要发生在下肢长骨关节外节段。肘部是发生骨样骨瘤的特殊部位。诊断通常延迟,因为肘部是这种肿瘤的罕见部位,非特异性临床症状,如单关节炎,可能模仿其他更常见的情况。我们报告的情况下,一个16岁的女孩谁提出慢性单关节炎的肘部被错误地治疗为结核性关节炎和单关节类风湿受累。化验结果呈阴性计算机断层扫描和磁共振成像显示尺骨冠突病灶病灶伴轻度滑膜炎。直到病情进展了18个月,肘部已经僵硬,才做出骨样骨瘤的诊断。经关节镜切除病变,病灶组织病理学符合骨样骨瘤。从那时起,患者肘部活动范围得到改善,不再疼痛。
{"title":"Monoarthritis of the Elbow Revealing Osteoid Osteoma: A Case Report and Literature Review","authors":"N. El Ouardi, S. Sadni, L. Taoubane, A. Mounach, A. Bezza","doi":"10.21802/gmj.2021.4.5","DOIUrl":"https://doi.org/10.21802/gmj.2021.4.5","url":null,"abstract":"Osteoid osteoma is a rare benign osteoblastic tumor that mainly occurs in the extra-articular segments of lower limb long bones. The elbow is an exceptional location for osteoid osteoma. \u0000The diagnosis is usually delayed since the elbow is a rare site for this tumor and unspecific clinical signs, such monoarthritis, may mimic other more common conditions. \u0000We report the case of a 16-year-old girl who presented with chronic monoarthritis of the elbow which was treated falsely as tuberculous arthritis and monoarticular rheumatoid involvement. \u0000The laboratory tests were negative. Computed tomography scan and magnetic resonance imaging showed the focal nidus at the coronoid process of the ulna with mild synovitis. The diagnosis of osteoid osteoma was not made until the disease had been progressing for eighteen months and the elbow had already become stiff. \u0000Arthroscopic excision of the lesion was performed, and histopathology of the nidus was consistent with osteoid osteoma. Since then, the patient has been pain-free with an improved elbow range of motion.","PeriodicalId":12537,"journal":{"name":"Galician Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46178712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of Educational Intervention on Care Dependency and Symptom Management After Hematopoietic Stem Cell Transplantation: A Theory-Based Randomized Controlled Study 教育干预对造血干细胞移植术后护理依赖和症状管理的影响:一项基于理论的随机对照研究
IF 0.1 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-12-01 DOI: 10.21802/gmj.2021.4.3
T. Menekli, B. Yaprak
The objective of the research was to determine the effect of educational intervention based on Bandura’s Social Cognitive Learning Theory on care dependency and symptom management after hematopoietic stem cell transplantation. Methods. This randomized controlled trial was conducted between January 2019 and February 2020 at the Hematopoietic Stem Cell Transplantation Center. All the patients were randomly divided into two groups: 53 individuals in the intervention group and 53 individuals in the control group. The sociodemographic data collection form, the Edmonton Symptom Assessment Scale and the Care Dependency Scale were used for data collection. Data were collected from the patients one day after hematopoietic stem cell transplantation and 12 weeks later. Results. There were no statistically significant differences between the groups regarding the mean scores of the Edmonton Symptom Assessment Scale and the Care Dependency Scale at baseline. Twelve weeks after intervention, there were statistically significant differences between the groups regarding the mean scores of the Edmonton Symptom Assessment Scale and the Care Dependency Scale. Conclusions. Educational intervention along with telephone counseling based on Bandura’s theory was found to be an effective way to reduce symptom severity and care dependency in patients who underwent hematopoietic stem cell transplantation and is recommended for all patients after hematopoietic stem cell transplantation.
本研究旨在探讨基于Bandura社会认知学习理论的教育干预对造血干细胞移植术后护理依赖和症状管理的影响。方法。这项随机对照试验于2019年1月至2020年2月在造血干细胞移植中心进行。所有患者随机分为两组:干预组53例,对照组53例。采用社会人口学数据收集表、埃德蒙顿症状评估量表和护理依赖量表进行数据收集。收集患者造血干细胞移植后1天和12周后的数据。结果。两组在基线时埃德蒙顿症状评估量表和护理依赖量表的平均得分无统计学差异。干预12周后,两组患者埃德蒙顿症状评估量表和护理依赖量表的平均得分差异有统计学意义。结论。基于Bandura理论的教育干预和电话咨询是降低造血干细胞移植患者症状严重程度和护理依赖性的有效方法,推荐用于所有造血干细胞移植后患者。
{"title":"The Effect of Educational Intervention on Care Dependency and Symptom Management After Hematopoietic Stem Cell Transplantation: A Theory-Based Randomized Controlled Study","authors":"T. Menekli, B. Yaprak","doi":"10.21802/gmj.2021.4.3","DOIUrl":"https://doi.org/10.21802/gmj.2021.4.3","url":null,"abstract":"The objective of the research was to determine the effect of educational intervention based on Bandura’s Social Cognitive Learning Theory on care dependency and symptom management after hematopoietic stem cell transplantation. \u0000Methods. This randomized controlled trial was conducted between January 2019 and February 2020 at the Hematopoietic Stem Cell Transplantation Center. All the patients were randomly divided into two groups: 53 individuals in the intervention group and 53 individuals in the control group. The sociodemographic data collection form, the Edmonton Symptom Assessment Scale and the Care Dependency Scale were used for data collection. Data were collected from the patients one day after hematopoietic stem cell transplantation and 12 weeks later. \u0000Results. There were no statistically significant differences between the groups regarding the mean scores of the Edmonton Symptom Assessment Scale and the Care Dependency Scale at baseline. Twelve weeks after intervention, there were statistically significant differences between the groups regarding the mean scores of the Edmonton Symptom Assessment Scale and the Care Dependency Scale. \u0000Conclusions. Educational intervention along with telephone counseling based on Bandura’s theory was found to be an effective way to reduce symptom severity and care dependency in patients who underwent hematopoietic stem cell transplantation and is recommended for all patients after hematopoietic stem cell transplantation.","PeriodicalId":12537,"journal":{"name":"Galician Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47059816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Psychometric Evaluation of the Diabetes Distress Scale in Patients with Type 2 Diabetes in Turkey 土耳其2型糖尿病患者糖尿病痛苦量表的心理测量评估
IF 0.1 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-12-01 DOI: 10.21802/gmj.2021.4.4
Nurten Terkeş, H. Bektaş
The objective of the research was to evaluate the validity and reliability of the Diabetes Distress Scale in patients with type 2 diabetes in Turkey. Materials and Methods. Our study was conducted between September 2016 and January 2017 and included 170 patients with type 2 diabetes. The Personal Information Form and Diabetes Distress Scale were used as a data collection tool. Statistical analysis was performed using SPSS 23.0 and SAS package program. Results. According to the results of the research, Cronbach’s alpha reliability for the total scale was 0.91. The model fit indices for the revised confirmatory factor analysis model failed to meet the criteria for acceptability: the GFI was 0.8185, the CFI was 0.9316, the Bentler - Bonett (1980) NFI was 0.9005, and the RMSEA was 0.1067. In our study, exploratory factor analysis provided support for the three-factor model: [I] emotional and regimen-related distress, [II] health professional-related distress, [III] diabetes-related interpersonal distress. Conclusions. When the translation and cultural adaptation process have been considered, the Diabetes Distress Scale is a valid and reliable tool for the Turkish community. It is recommended to be used in the studies and clinical trials.
本研究的目的是评估糖尿病困扰量表在土耳其2型糖尿病患者中的有效性和可靠性。材料与方法。我们的研究于2016年9月至2017年1月进行,包括170名2型糖尿病患者。使用个人信息表和糖尿病困扰量表作为数据收集工具。采用SPSS 23.0和SAS软件包程序进行统计学分析。结果。根据研究结果,总量表的Cronbach 's alpha信度为0.91。修正后的验证性因子分析模型的模型拟合指标不符合可接受性标准:GFI为0.8185,CFI为0.9316,Bentler - Bonett (1980) NFI为0.9005,RMSEA为0.1067。在我们的研究中,探索性因子分析为三因素模型提供了支持:[I]情绪和方案相关的痛苦,[II]卫生专业相关的痛苦,[III]糖尿病相关的人际关系痛苦。结论。当考虑到翻译和文化适应过程时,糖尿病困扰量表对土耳其社区来说是一个有效和可靠的工具。建议在研究和临床试验中使用。
{"title":"Psychometric Evaluation of the Diabetes Distress Scale in Patients with Type 2 Diabetes in Turkey","authors":"Nurten Terkeş, H. Bektaş","doi":"10.21802/gmj.2021.4.4","DOIUrl":"https://doi.org/10.21802/gmj.2021.4.4","url":null,"abstract":"The objective of the research was to evaluate the validity and reliability of the Diabetes Distress Scale in patients with type 2 diabetes in Turkey. \u0000Materials and Methods. Our study was conducted between September 2016 and January 2017 and included 170 patients with type 2 diabetes. The Personal Information Form and Diabetes Distress Scale were used as a data collection tool. Statistical analysis was performed using SPSS 23.0 and SAS package program. \u0000Results. According to the results of the research, Cronbach’s alpha reliability for the total scale was 0.91. The model fit indices for the revised confirmatory factor analysis model failed to meet the criteria for acceptability: the GFI was 0.8185, the CFI was 0.9316, the Bentler - Bonett (1980) NFI was 0.9005, and the RMSEA was 0.1067. In our study, exploratory factor analysis provided support for the three-factor model: [I] emotional and regimen-related distress, [II] health professional-related distress, [III] diabetes-related interpersonal distress. \u0000Conclusions. When the translation and cultural adaptation process have been considered, the Diabetes Distress Scale is a valid and reliable tool for the Turkish community. It is recommended to be used in the studies and clinical trials.","PeriodicalId":12537,"journal":{"name":"Galician Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47793942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Reproducibility of Retinal Nerve Fiber Layer and Macular Thickness Measurements Using Spectral Domain Optical Coherence Tomography 利用光谱域光学相干断层扫描测量视网膜神经纤维层和黄斑厚度的可重复性
IF 0.1 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-12-01 DOI: 10.21802/gmj.2021.4.7
A. Sood, R. Paliwal, R. Mishra
The objective of the research was to assess the reproducibility of retinal nerve fiber layer (RNFL) and macular thickness using spectral domain optical coherence tomography and to establish whether the same investigator can get the same or similar results when performing the scan thrice in an hour, without reference to the previous scan and the repeat function. Materials and Methods. In this prospective observational study, 200 subjects who fulfilled the inclusion and exclusion criteria were scanned 3 times according to predefined guidelines at 0, 30 and 60 minutes on the same day, by the same investigator, using spectral domain optical coherence tomography for measurements of RNFL and macular thickness; observations were statistically analyzed and correlated. Results. In RNFL thickness, the temporal sector showed the worst reproducibility as compared to other sectors. RNFL was the greatest in the superior quadrant and the thinnest in the temporal quadrant. For macular thickness, the temporal sector (mid zone) showed the worst reproducibility, while in the outer zone, the inferior sector showed the worst reproducibility; macular thickness was the thinnest at the central zone (innermost 1-mm ring), the thickest within the inner 3-mm ring and diminished peripherally. Conclusions. RNFL and macular thickness measurements using spectral domain optical coherence tomography by the same observer at 0, 30 and 60 minutes were very reproducible, except for the sectors specifically mentioned. The greater the thickness of the RNFL in any sector the better was the reproducibility in that sector. For macular thickness, the temporal sector (mid zone) showed the worst reproducibility.
本研究的目的是利用光谱域光学相干断层扫描评估视网膜神经纤维层(RNFL)和黄斑厚度的可重复性,并确定同一研究者在一小时内进行三次扫描时,是否可以在不参考前一次扫描和重复功能的情况下获得相同或相似的结果。材料与方法。在这项前瞻性观察性研究中,200名符合纳入和排除标准的受试者在同一天的0、30和60分钟,由同一研究者按照预先设定的指南扫描3次,使用光谱域光学相干断层扫描测量RNFL和黄斑厚度;观察结果进行统计学分析和相关分析。结果。在RNFL厚度上,颞部的再现性最差。RNFL在上象限最大,在颞象限最薄。对于黄斑厚度,颞区(中部)的再现性最差,而在外区,下区再现性最差;黄斑厚度在中心区域(最内层1 mm环)最薄,在内层3 mm环内最厚,周围逐渐减少。结论。同一观测者在0、30和60分钟使用光谱域光学相干断层扫描进行RNFL和黄斑厚度测量,除特别提到的部分外,重复性非常好。任何扇区的RNFL厚度越大,该扇区的再现性越好。对于黄斑厚度,颞区(中间区)的再现性最差。
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引用次数: 1
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Galician Medical Journal
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