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The Discovery of Coronavirus – An Interesting Journey 冠状病毒的发现——一段有趣的旅程
IF 0.1 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-09-01 DOI: 10.21802/gmj.2021.3.1
Kaushik Bhattacharya, N. Bhattacharya, A. Bhattacharya
The coronavirus, which is causing the ongoing Covid-19 pandemic and has crippled the entire world, was discovered by June Dalziel Almeida - a school dropout from Scotland who had no formal medical education. She had to master the knowhow of immune electron microscopy to climb up the academic ladder and she finally discovered the coronavirus only to see her research paper getting rejected by reputed journals. A single mother is now associated with the coronavirus, as well as with a significant contribution to the classification of viruses, viral imaging and bringing Rubella virus, Hepatitis B virus and Human immunodeficiency virus into the limelight.
新冠病毒是由June Dalziel Almeida发现的,他是苏格兰的一名辍学者,没有接受过正规医学教育。她必须掌握免疫电子显微镜的专业知识才能登上学术阶梯,她最终发现了冠状病毒,但她的研究论文却被知名期刊拒绝了。单身母亲现在与冠状病毒有关,对病毒分类、病毒成像做出了重大贡献,并使风疹病毒、乙型肝炎病毒和人类免疫缺陷病毒成为焦点。
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引用次数: 0
Features of Changes in the Structural and Functional State of the Myocardium in Patients with Acute Myocardial Infarction Depending on Body Mass Index Considering FABP4 and CTRP3 Levels 考虑FABP4和CTRP3水平的体重指数对急性心肌梗死患者心肌结构和功能变化的影响
IF 0.1 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-09-01 DOI: 10.21802/gmj.2021.3.7
M. Koteliukh
Introduction. Adipokines such as fatty acid-binding protein 4 (FABP4) and C1q tumor necrosis factor-related protein 3 (CTRP3) can affect the structural and functional state of the myocardium in patients with acute myocardial infarction and obesity. The objective of the research was to determine the relationship between FABP4, CTRP3 and echocardiographic parameters of the left ventricular myocardium in patients with acute myocardial infarction depending on body mass index. Materials and Methods. The observational cross-sectional study examined 189 patients with acute myocardial infarction depending on body mass index, who were divided into the following groups: Group 1 included 60 patients with acute myocardial infarction and normal body mass index; Group 2 comprised 68 patients with acute myocardial infarction and excess body weight; Group 3 included 61 patients with acute myocardial infarction and obesity. Results. In Group 1, the statistical significance correlations were found: between FABP4 and end-diastolic dimension (EDD; r = -0.458), end-systolic dimension (ESD; r = -0.460), end-diastolic volume (EDV; r = -0.452), left ventricular myocardial mass (LVMM; r = -0.411), LVMM/body surface area index (LVMMI2; r = -0.419); between CTRP3 and EDV (r = 0.425), EDD (r = 0.469), left ventricular relative posterior wall thickness (LVRPWT; r = -0.469). In Group 2, there were found the statistical significance relationships between: FABP4 and EDD (r = 0.461), ESD (r = 0.467), EDV (r = 0.449), end-systolic volume (ESV; r = 0.485), LVMM (r = 0.487), LVMMI1 (r = 0.406); between CTRP3 and EDD (r = -0.440), EDV (r = -0.413), LVMM (r = -0.430), LVMM/height2.7 index (LVMMI1; r = -0.483). In Group 3, the statistical significance correlations were found between: FABP4 and EDV (r = 0.481), ESD (r = 0.411), ESV (r = 0.490), LVMMI1 (r = 0.403); between CTRP3 and EDV (r = -0.326), ESD (r = -0.367), ESV (r = -0.453), LVMMI1 (r = -0.415). Conclusions. In patients with acute myocardial infarction and overweight/obesity, echocardiographic parameters had a significant low positive correlation with FABP4 and a low negative correlation with CTRP3. On the contrary, in patients with acute myocardial infarction and normal body mass index, echocardiographic parameters had a significant low negative correlation with FABP4 and a low positive correlation with CTRP3.
介绍脂肪酸结合蛋白4(FABP4)和C1q肿瘤坏死因子相关蛋白3(CTRP3)等脂肪因子可影响急性心肌梗死和肥胖患者心肌的结构和功能状态。本研究的目的是根据体重指数确定FABP4、CTRP3与急性心肌梗死患者左心室心肌超声心动图参数之间的关系。材料和方法。这项观察性横断面研究根据体重指数检查了189名急性心肌梗死患者,他们被分为以下组:第一组包括60名急性心肌梗塞和正常体重指数的患者;第2组包括68名急性心肌梗死和超重患者;第3组包括61例急性心肌梗死和肥胖患者。后果在第1组中,发现FABP4与舒张末期尺寸(EDD;r=-0.458)、收缩末期尺寸(ESD;r=-0.460)、舒张末期容积(EDV;r=-0.452)、左心室心肌质量(LVMM;r=-0.411)、LVMM/体表面积指数(LVMMI2;r=-0.419)之间存在统计学显著相关性;CTRP3与EDV(r=0.425)、EDD(r=0.469)、左心室相对后壁厚度(LVRPWT;r=-0.469)之间存在统计学显著性关系:FABP4与EDD(r=0.461)、ESD(r=0.467)、EDV(r=0.449)、收缩末期容积(ESV;r=0.485)、LVMM(r=0.487)、LVMMI1(r=0.406);CTRP3与EDD(r=-0.440)、EDV(r=-0.413)、LVMM(r=-0.430)、LVMM/height2.7指数(LVMMI1;r=-0.483)之间存在统计学显著性相关性;CTRP3与EDV(r=-0.326)、ESD(r=-0.367)、ESV(r=0.453)、LVMMI1(r=-0.415)的相关性。在急性心肌梗死和超重/肥胖患者中,超声心动图参数与FABP4呈显著的低正相关,与CTRP3呈低负相关。相反,在急性心肌梗死和体重指数正常的患者中,超声心动图参数与FABP4呈显著的低负相关,与CTRP3呈低正相关。
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引用次数: 0
Assessment of Nursing Students’ Attitudes Towards Recording and Protecting Patients’ Personal Health Data: A Descriptive Study 护生对记录和保护病人个人健康资料态度的评估:一项描述性研究
IF 0.1 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-09-01 DOI: 10.21802/gmj.2021.3.3
Sebahat Atalıkoğlu Başkan, Papatya Karakurt, Necla Kasımoğlu
Introduction. Since health information is considered as sensitive personal data and requires more careful protection, healthcare professionals need to be careful about this issue. The objective of this research was to determine nursing students’ attitudes towards recording and protecting patients’ personal health data. Materials and Methods. The population of this descriptive research consisted of 450 students who studied at the Department of Nursing, Faculty of Health Sciences, Erzincan Binali Yildirim University. Sample selection was not used, and the research was completed with 374 students who were continuing education and who were accepted to participate in the research. Descriptive Information template and Attitude Scale for Recording and Protecting Personal Health Data for nursing students were used as data-collection instruments. The numbers, percentage, mean, standard deviation, non-parametric tests (the Mann-Whitney U test and the Kruskal-Wallis test) were used in data analysis. Results. Among our research participants, 68.4% of the students were females; 28.1% of the students were freshmen; 69% of the students were graduates of Anatolian high schools. Approximately 72.5% and 52.9% of the participants stated that they were aware of the concept of “personal data” and “personal health data” , respectively. The mean score of nursing students on the Attitude Scale for Recording and Protecting Personal Health Data was 3.97±0.71. The means scores obtained from subscales were as follows: 3.91±0.72 for Personal Health Data Information, 4.15±0.80 for Legal Information, 4.05±0.94 for Legal Data Sharing, 3.90±0.80 for Personal Health Data Sharing, and 3.77±0.33 for Recording of Personal Health Data, respectively. A statistically significant difference was found between the total scale and subscale scores of the students regarding their academic level. Conclusions. Students were found to have a positive attitude towards recording and protecting personal data. Increasing the responsibilities and raising awareness of the students for the protection of personal health data during their study is suggested to be important.
介绍。由于健康信息被视为敏感的个人数据,需要更仔细的保护,因此医疗保健专业人员需要谨慎对待这个问题。本研究的目的是确定护理学生对记录和保护患者个人健康数据的态度。材料与方法。这项描述性研究的人口包括在Erzincan Binali Yildirim大学健康科学学院护理系学习的450名学生。本研究未采用抽样方法,选取了374名接受继续教育的学生作为研究对象。采用《护生个人健康资料记录与保护态度量表》和《描述性信息模板》作为数据收集工具。数据分析采用数字、百分比、均值、标准差、非参数检验(Mann-Whitney U检验和Kruskal-Wallis检验)。结果。在我们的研究参与者中,68.4%的学生是女性;新生占28.1%;69%的学生毕业于安纳托利亚高中。约72.5%及52.9%的参与者分别表示知悉"个人资料"及"个人健康资料"的概念。护生个人健康资料记录与保护态度量表平均得分为3.97±0.71。各子量表的平均得分分别为:个人健康数据信息(3.91±0.72)、法律信息(4.15±0.80)、法律数据共享(4.05±0.94)、个人健康数据共享(3.90±0.80)、个人健康数据记录(3.77±0.33)。学生学业水平的总量表得分与子量表得分有显著性差异。结论。调查发现,学生对记录及保护个人资料持积极态度。建议增加学生在学习期间保护个人健康数据的责任和提高他们的意识是重要的。
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引用次数: 2
Level of Knowledge and Awareness of Diabetic Emergencies Among Turkish Bus Drivers: Example of the Mediterranean Region 土耳其公交车司机对糖尿病紧急情况的知识和意识水平:以地中海地区为例
IF 0.1 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-09-01 DOI: 10.21802/gmj.2021.3.5
Sibel Şentürk, Nurten Terkeş
The objective of this research was to determine the level of knowledge and awareness of diabetic emergencies among Turkish bus drivers. Methods. The universe of this descriptive and cross-sectional study was all the individuals working as bus drivers in the Mediterranean Region between January-June 2019, and the study sample was 1292 drivers who met the inclusion criteria of the research. Data were collected by the Personal Information Form and the Diabetic Emergency Information and Awareness Survey Form. Descriptive statistics, the Mann-Whitney U test and the Kruskal-Wallis test were used in data evaluation. Results. The average age of bus drivers participating in the study was 38.29 ± 9.44 years, while their average work experience was 12.50 ± 8.92 years. Among them, 14.9% of bus drivers had a diabetic family member; 23.7% of bus drivers had a first aid certificate; 11.5% of bus drivers received diabetes-related training. The average score of drivers for the level of knowledge and awareness regarding diabetic emergencies was found to be 15.39 ± 4.72. There was a statistically significant difference between the drivers’ average scores for the level of knowledge and awareness and their age, education status, work experience, the presence of chronic disease, the presence of a diabetic family member, the presence of a first aid certificate, diabetes-related training, the place of receiving this training variables (p < 0.05). Conclusions. Bus drivers were found to have above average levels of knowledge and awareness of diabetic emergencies. Bus drivers are recommended to be trained on diabetic emergencies and raising awareness of diabetes mellitus to ensure a proper intervention in case of emergencies in individuals with diabetes mellitus during travels.
这项研究的目的是确定土耳其公交车司机对糖尿病紧急情况的知识和意识水平。方法。这项描述性和横断面研究的对象是2019年1月至6月期间在地中海地区担任公交车司机的所有人,研究样本为1292名符合研究纳入标准的司机。数据通过个人信息表和糖尿病急诊信息和意识调查表收集。数据评估采用描述性统计、Mann-Whitney U检验和Kruskal-Wallis检验。后果参与研究的公交车司机的平均年龄为38.29±9.44岁,而他们的平均工作经验为12.50±8.92岁。其中,14.9%的公交车司机有糖尿病家庭成员;23.7%的公交车司机有急救证书;11.5%的公交车司机接受了糖尿病相关培训。驾驶员对糖尿病紧急情况的知识和意识水平的平均得分为15.39±4.72。驾驶员的知识和意识水平的平均得分与他们的年龄、教育状况、工作经历、是否患有慢性病、是否有糖尿病家庭成员、是否有急救证书、是否接受糖尿病相关培训、接受培训的地点之间存在统计学上的显著差异(p<0.05)。结论。公交车司机被发现对糖尿病紧急情况的知识和意识水平高于平均水平。建议公交车司机接受糖尿病紧急情况培训,并提高对糖尿病的认识,以确保在旅途中糖尿病患者出现紧急情况时进行适当干预。
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引用次数: 0
Oral and Dental Manifestations of Fanconi Anemia 范可尼贫血的口腔和牙齿表现
IF 0.1 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-09-01 DOI: 10.21802/gmj.2021.3.2
V. Ambarkova
Fanconi anemia is a rare disease, which is characterized by decreased production of all blood cell types. Fanconi anemia is the most common inherited form of aplastic anemia. Congenital abnormalities of the eyes, ears, and heart, malformed or absent kidney, urogenital system involvement are common. There is a delay in physical development. Intelligence in patients with Fanconi anemia is usually normal. The most serious problems associated with Fanconi anemia include the gradual development of bone marrow disorders. Many patients with Fanconi anemia develop leukemia or myelodysplastic syndrome, as well as other oncological diseases. Oral manifestations in patients with Fanconi anemia can be classified as gingivitis, periodontitis, dental caries, dental anomalies, soft tissue lesions, oral cancer, and lesions of the tongue. Patients with Fanconi anemia have increased predisposition to squamous cell carcinoma of the head and neck and oral cancer. The interdisciplinary team of medical and dental specialists must be included in the medical and dental treatment of patients with Fanconi anemia. For proper dental care of patients with Fanconi anemia, the close cooperation of dental specialists, including orthodontists, pedodontists, prosthetists, oral surgeons, as well as specialists in periodontology and oral diseases, is of particular importance.
范科尼贫血是一种罕见的疾病,其特征是所有类型的血细胞产生减少。范科尼贫血是再生障碍性贫血最常见的遗传形式。先天性眼睛、耳朵和心脏异常,肾脏畸形或缺失,泌尿生殖系统受累是常见的。身体发育迟缓。范科尼贫血患者的智力通常是正常的。与范科尼贫血相关的最严重的问题包括骨髓疾病的逐渐发展。许多范科尼贫血患者会发展为白血病或骨髓增生异常综合征,以及其他肿瘤学疾病。范可尼贫血患者的口腔表现可分为牙龈炎、牙周炎、龋齿、牙齿异常、软组织病变、口腔癌症和舌头病变。凡科尼贫血患者易患头颈部鳞状细胞癌和口腔癌症。由医学和牙科专家组成的跨学科团队必须参与Fanconi贫血患者的医学和牙科治疗。为了对范科尼贫血患者进行适当的牙科护理,牙科专家的密切合作尤其重要,包括正畸医生、儿童牙科医生、修复师、口腔外科医生以及牙周病和口腔疾病专家。
{"title":"Oral and Dental Manifestations of Fanconi Anemia","authors":"V. Ambarkova","doi":"10.21802/gmj.2021.3.2","DOIUrl":"https://doi.org/10.21802/gmj.2021.3.2","url":null,"abstract":"Fanconi anemia is a rare disease, which is characterized by decreased production of all blood cell types. Fanconi anemia is the most common inherited form of aplastic anemia. Congenital abnormalities of the eyes, ears, and heart, malformed or absent kidney, urogenital system involvement are common. There is a delay in physical development. Intelligence in patients with Fanconi anemia is usually normal. The most serious problems associated with Fanconi anemia include the gradual development of bone marrow disorders. Many patients with Fanconi anemia develop leukemia or myelodysplastic syndrome, as well as other oncological diseases. Oral manifestations in patients with Fanconi anemia can be classified as gingivitis, periodontitis, dental caries, dental anomalies, soft tissue lesions, oral cancer, and lesions of the tongue. Patients with Fanconi anemia have increased predisposition to squamous cell carcinoma of the head and neck and oral cancer. The interdisciplinary team of medical and dental specialists must be included in the medical and dental treatment of patients with Fanconi anemia. For proper dental care of patients with Fanconi anemia, the close cooperation of dental specialists, including orthodontists, pedodontists, prosthetists, oral surgeons, as well as specialists in periodontology and oral diseases, is of particular importance.","PeriodicalId":12537,"journal":{"name":"Galician Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49017177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Online Learning Modules in Anatomical Sciences: Effective Sources for Continued Learning for Medical Undergraduates During the Unprecedent COVID-19 Pandemic 解剖科学在线学习模块:在前所未有的COVID-19大流行期间医学本科生继续学习的有效来源
IF 0.1 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-09-01 DOI: 10.21802/gmj.2021.3.6
S. Viveka, N. Pushpa, K. Ravi
Introduction. During the COVID-19 pandemic-induced lockdown, the selection of simple and authentic online material among plethora of web content is difficult for both students and teachers. This forces students and teachers to explore various avenues of learning. The objective of this research was to evaluate free open-access anatomy e-learning resources in accordance with required standard learning outcomes for medical students. Methods. During February 2021, an extensive search for online modules for learning anatomy across six Massive Open Online Courses, including edX, Coursera, Udemy, Khan Academy, Canvas and FutureLearn, along with Google and YouTube was conducted. Courses or modules on e-learning platforms, YouTube channels, standalone videos, anatomy atlases, 3D models were considered as learning resources and evaluated. Online materials were classified as structured learning resources if they had a defined syllabus, time duration and instructional design. Resources lacking these characteristics were considered as unstructured ones. Results. Twenty structured learning courses were identified on the Udemy (6 courses), Coursera (3 courses), edX (2 courses), FutureLearn and Khan academy platforms. Learning resources available through Swayam Prabha were aligned with the defined syllabus and video lectures. The content hosted within Clinical Anatomy, Medvizz and Kenhub was eye-catching. Thirty-two YouTube channels offering standalone learning material were identified. Seven resource materials, other than YouTube channels, offered anatomy learning material in the form of charts and tables. Four websites noted to have 3D interactive learning content regarding gross anatomy. Conclusions. During the pandemic-induced lockdown, the list presented in the study may act as guide in selection of the simplest and best materials for those teaching and learning anatomy in medical undergraduate courses. However, in most cases, there is no alignment with standard learning outcomes as defined by medical education regulatory authorities.
介绍。在COVID-19大流行引发的封锁期间,学生和教师都很难从大量网络内容中选择简单而真实的在线材料。这迫使学生和教师探索各种学习途径。本研究的目的是评估免费开放存取的解剖学电子学习资源,以符合医学生所需的标准学习成果。方法。在2021年2月期间,对六门大规模开放在线课程(包括edX, Coursera, Udemy, Khan Academy, Canvas和FutureLearn)以及谷歌和YouTube进行了广泛的在线模块搜索,以学习解剖学。在线学习平台、YouTube频道、独立视频、解剖图集、3D模型等课程或模块被视为学习资源并进行评估。如果在线材料具有明确的教学大纲、时间长度和教学设计,则将其归类为结构化学习资源。缺乏这些特征的资源被认为是非结构化资源。结果。在Udemy(6门课程)、Coursera(3门课程)、edX(2门课程)、FutureLearn和可汗学院平台上确定了20门结构化学习课程。通过Swayam Prabha提供的学习资源与定义的教学大纲和视频讲座保持一致。Clinical Anatomy、Medvizz和Kenhub上的内容非常引人注目。确定了32个提供独立学习材料的YouTube频道。除了YouTube频道外,还有7个资源材料以图表的形式提供解剖学学习材料。有四个网站指出有关于大体解剖的3D互动学习内容。结论。在疫情封锁期间,本研究提出的清单可为医学本科解剖教学人员选择最简单、最好的材料提供指导。然而,在大多数情况下,与医学教育监管机构定义的标准学习成果不一致。
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引用次数: 0
Dual-Energy Multidetector Computed Tomography: A Highly Accurate Non-Invasive Tool for in Vivo Determination of Chemical Composition of Renal Calculi 双能多探测器计算机断层扫描:一种高度准确的非侵入性体内肾结石化学成分测定工具
IF 0.1 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-09-01 DOI: 10.21802/gmj.2021.3.4
Shafqat Shabir Bhawani, M. Jehangir, Mohammad Masood, S. Dar, Sajad Nazir Syed
Introduction. Computed tomography is more accurate than excretory urography in evaluation of renal stones due to its high sensitivity and temporal resolution; it permits sub-millimetric evaluation of the size and site of calculi but cannot evaluate their chemical composition. Dual-energy computed tomography allows evaluating the chemical composition of urinary calculi using simultaneous image acquisition at two different energy levels. The objective of the research was to determine renal stone composition using dual-energy multidetector computed tomography, and its correlation with post-extraction chemical analysis of stones. Materials and Methods. This prospective study was conducted in the Department of Radiodiagnosis and Imaging from September 2017 to March 2019. A total of 50 patients with urolithiasis at the age of 18-70 years were included in the study. Dual-energy computed tomography ratios of various stones were noted, and preoperative composition of calculi was given based on their colour and dual-energy computed tomography ratio. These results were compared with the post-extraction chemical analysis of stones (using Fourier infrared transform spectroscopy as the standard comparative method.) Results. The most common type of calculi in our study population was calcium oxalate stones (78%) followed by uric acid stones (12%), cystine stones (6%) and hydroxyapatite stones (4%). The dual-energy ratio of calcium oxalate, uric acid, cystine and hydroxyapatite stones ranged from 1.38-1.59, 0.94-1.08, and 1.20-1.28 and 1.52-1.57, respectively, with the mean dual-energy ratio of 1.43, 1.01, 1.25 and 1.55, respectively. Dual-energy computed tomography was found to be 100% sensitive and specific for differentiating uric acid stones from non‑uric acid stones. The sensitivity and specificity in differentiating calcium oxalate calculus from non‑calcium oxalate calculus was 97.5% and 90.9%, respectively, with 96% accuracy and kappa value of 0.883 suggesting strong agreement. Conclusions. Dual-energy computed tomography is highly sensitive and accurate in distinguishing between various types of renal calculi. It has vital role in management as uric acid calculi are amenable to drug treatment, while most of non-uric acid calculi require surgical intervention.
介绍。计算机断层扫描由于其高灵敏度和时间分辨率,在评估肾结石方面比排泄尿路造影更准确;它允许对结石的大小和位置进行亚毫米级的评估,但不能评估它们的化学成分。双能量计算机断层扫描允许在两个不同的能量水平上同时获取图像来评估尿路结石的化学成分。本研究的目的是利用双能多检测器计算机断层扫描确定肾结石的组成,以及其与提取后结石化学分析的相关性。材料与方法。这项前瞻性研究于2017年9月至2019年3月在放射诊断和影像学进行。本研究共纳入50例年龄在18-70岁的尿石症患者。记录各种结石的双能ct比,并根据结石的颜色和双能ct比给出术前结石的组成。这些结果与提取后的石头化学分析(使用傅里叶红外变换光谱作为标准比较方法)进行了比较。结果。在我们的研究人群中最常见的结石类型是草酸钙结石(78%),其次是尿酸结石(12%)、胱氨酸结石(6%)和羟基磷灰石结石(4%)。草酸钙、尿酸、胱氨酸和羟基磷灰石结石的双能比分别为1.38 ~ 1.59、0.94 ~ 1.08、1.20 ~ 1.28和1.52 ~ 1.57,平均双能比分别为1.43、1.01、1.25和1.55。双能计算机断层扫描被发现对区分尿酸结石和非尿酸结石具有100%的敏感性和特异性。鉴别草酸钙结石和非草酸钙结石的敏感性和特异性分别为97.5%和90.9%,准确率为96%,kappa值为0.883,一致性强。结论。双能计算机断层扫描对不同类型肾结石的鉴别具有高度的敏感性和准确性。尿酸型结石可通过药物治疗,而非尿酸型结石多数需要手术治疗,因此尿酸型结石在治疗中具有重要作用。
{"title":"Dual-Energy Multidetector Computed Tomography: A Highly Accurate Non-Invasive Tool for in Vivo Determination of Chemical Composition of Renal Calculi","authors":"Shafqat Shabir Bhawani, M. Jehangir, Mohammad Masood, S. Dar, Sajad Nazir Syed","doi":"10.21802/gmj.2021.3.4","DOIUrl":"https://doi.org/10.21802/gmj.2021.3.4","url":null,"abstract":"Introduction. Computed tomography is more accurate than excretory urography in evaluation of renal stones due to its high sensitivity and temporal resolution; it permits sub-millimetric evaluation of the size and site of calculi but cannot evaluate their chemical composition. Dual-energy computed tomography allows evaluating the chemical composition of urinary calculi using simultaneous image acquisition at two different energy levels. \u0000The objective of the research was to determine renal stone composition using dual-energy multidetector computed tomography, and its correlation with post-extraction chemical analysis of stones. \u0000Materials and Methods. This prospective study was conducted in the Department of Radiodiagnosis and Imaging from September 2017 to March 2019. A total of 50 patients with urolithiasis at the age of 18-70 years were included in the study. Dual-energy computed tomography ratios of various stones were noted, and preoperative composition of calculi was given based on their colour and dual-energy computed tomography ratio. These results were compared with the post-extraction chemical analysis of stones (using Fourier infrared transform spectroscopy as the standard comparative method.) \u0000Results. The most common type of calculi in our study population was calcium oxalate stones (78%) followed by uric acid stones (12%), cystine stones (6%) and hydroxyapatite stones (4%). The dual-energy ratio of calcium oxalate, uric acid, cystine and hydroxyapatite stones ranged from 1.38-1.59, 0.94-1.08, and 1.20-1.28 and 1.52-1.57, respectively, with the mean dual-energy ratio of 1.43, 1.01, 1.25 and 1.55, respectively. Dual-energy computed tomography was found to be 100% sensitive and specific for differentiating uric acid stones from non‑uric acid stones. The sensitivity and specificity in differentiating calcium oxalate calculus from non‑calcium oxalate calculus was 97.5% and 90.9%, respectively, with 96% accuracy and kappa value of 0.883 suggesting strong agreement. \u0000Conclusions. Dual-energy computed tomography is highly sensitive and accurate in distinguishing between various types of renal calculi. It has vital role in management as uric acid calculi are amenable to drug treatment, while most of non-uric acid calculi require surgical intervention.","PeriodicalId":12537,"journal":{"name":"Galician Medical Journal","volume":"1 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41576423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Examination of Affiliate Stigma, Hopelessness and Life Satisfaction in Parents of Children with Intellectual Disabilty 智障儿童父母相关污名感、无望感与生活满意度的研究
IF 0.1 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-06-01 DOI: 10.21802/GMJ.2021.2.3
Necla Kasımoğlu, D. Arikan
Introduction. While expecting a healthy child, having a child with a disability can be quite traumatic for all family members, especially parents. The objective of the research was to evaluate affiliate stigma, hopelessness, and life satisfaction in parents of children with intellectual disability. Materials and Methods. The descriptive research included 203 parents of children with intellectual disabilities, who met the research inclusion criteria and agreed to participate in the study. The data were collected using the Personal Information Form, the Affiliate Stigma Scale, the Beck Hopelessness Scale, and the Satisfaction with Life Scale. Results. The mean age of parents included in the study was 40.74 ± 7.22 years, with 67.5% of caregiving mothers. The levels of affiliate stigma and hopelessness among parents were low, and they were satisfied with their lives. In case of increasing parental affiliate stigma, their hopelessness was found to increase, while life satisfaction was found to decrease. Conclusions. In order to increase public acceptance of people with disabilities by society, it is recommended to provide trainings and raise awareness against individuals with disabilities and their families.
介绍。虽然期待一个健康的孩子,但有一个残疾的孩子对所有家庭成员,尤其是父母来说都是相当痛苦的。本研究的目的是评估智障儿童父母的附属污名、绝望和生活满意度。材料与方法。描述性研究包括203名智力残疾儿童的父母,他们符合研究纳入标准并同意参与研究。数据采用个人信息表、附属污名量表、贝克绝望量表和生活满意度量表收集。结果。参与研究的父母平均年龄为40.74±7.22岁,其中照顾母亲占67.5%。父母们的附属耻辱和绝望程度很低,他们对自己的生活很满意。在父母关系污名增加的情况下,他们的绝望感增加,而生活满意度降低。结论。为了提高社会对残疾人的公众接受度,建议提供培训并提高对残疾人个人及其家庭的认识。
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引用次数: 1
Ogilvie Syndrome Following Caesarean Section: A Case Report 剖宫产术后Ogilvie综合征一例报告
IF 0.1 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-06-01 DOI: 10.21802/GMJ.2021.2.6
S. Sninate, H. Bellamlih, S. Allioui, L. Jroundi, F. Laamrani
Background. Ogilvie syndrome is a rare postpartum complication. It is characterized by an acute colonic pseudo-obstruction which occurs in the absence of a mechanical cause. Early detection of the diagnosis is essential to avoid cecal perforation. Case report. We report a case of Ogilvie syndrome following caesarean section in a 39-year-old woman (gravida 2, para 2) with a history of secondary infertility 10 years ago due to tubal stenosis and subserous fibroma, which led to the indication for cesarean section in second pregnancy at 39 weeks of gestation. Three days after cesarean section, the patient presented with significant abdominal distension and tenderness, vomiting, weakness, and nausea; an abdominal X-ray showed cecal distension. Abdominal computed tomography scan with intravenous contrast revealed distension of the ascending and transverse colon with air-fluid levels but without transitional mechanical obstruction. The patient was successfully treated. Conclusions. Ogilvie syndrome is a rare but serious complication that should be considered in fit young patients who present with pain, severe abdominal distension and failure to pass flatus after caesarean section.
背景。奥吉维综合征是一种罕见的产后并发症。它的特点是急性结肠假性梗阻,发生在没有机械原因。早期诊断对避免盲肠穿孔至关重要。病例报告。我们报告一例39岁女性(妊娠期2,第2段)剖宫产后出现Ogilvie综合征,10年前因输卵管狭窄和浆膜下纤维瘤继发性不孕症,导致妊娠39周第二次妊娠剖宫产指征。剖宫产术后3天,患者出现明显腹胀、压痛、呕吐、虚弱、恶心;腹部x光片显示盲肠膨胀。腹部计算机断层扫描和静脉造影剂显示升结肠和横结肠膨胀伴气液水平,但无过渡性机械阻塞。病人得到了成功的治疗。结论。奥吉维综合征是一种罕见但严重的并发症,在健康的年轻患者中,剖宫产后出现疼痛、严重腹胀和排气失败应予以考虑。
{"title":"Ogilvie Syndrome Following Caesarean Section: A Case Report","authors":"S. Sninate, H. Bellamlih, S. Allioui, L. Jroundi, F. Laamrani","doi":"10.21802/GMJ.2021.2.6","DOIUrl":"https://doi.org/10.21802/GMJ.2021.2.6","url":null,"abstract":"Background. Ogilvie syndrome is a rare postpartum complication. It is characterized by an acute colonic pseudo-obstruction which occurs in the absence of a mechanical cause. Early detection of the diagnosis is essential to avoid cecal perforation. \u0000 Case report. We report a case of Ogilvie syndrome following caesarean section in a 39-year-old woman (gravida 2, para 2) with a history of secondary infertility 10 years ago due to tubal stenosis and subserous fibroma, which led to the indication for cesarean section in second pregnancy at 39 weeks of gestation. Three days after cesarean section, the patient presented with significant abdominal distension and tenderness, vomiting, weakness, and nausea; an abdominal X-ray showed cecal distension. Abdominal computed tomography scan with intravenous contrast revealed distension of the ascending and transverse colon with air-fluid levels but without transitional mechanical obstruction. The patient was successfully treated. \u0000Conclusions. Ogilvie syndrome is a rare but serious complication that should be considered in fit young patients who present with pain, severe abdominal distension and failure to pass flatus after caesarean section.","PeriodicalId":12537,"journal":{"name":"Galician Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42008224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mucinous Cystadenoma of the Ovary Associated with Hyperplasia of Stromal Leydig Cells in Pregnant Woman 孕妇卵巢粘液性囊腺瘤伴基质间质细胞增生
IF 0.1 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-06-01 DOI: 10.21802/GMJ.2021.2.5
V. Bartoš
Background: The hormonally induced non-neoplastic lesions of ovarian stroma during pregnancy must be recognized by pathologist in order to avoid mistaking them for true tumors. Case report: A 28-year-old woman was delivered of a healthy infant by cesarean section. As an incidental finding, a multicystic tumor in the left ovary was found and resected. Histopathology was consistent with benign mucinous cystadenoma. In addition, within the stroma beneath the lining mucinous epithelium, a dense population of cohesive polygonal cells with abundant eosinophilic cytoplasm, typically resembling the Leydig cells, was seen. They were uniform without atypia, accompaning by minimal proliferative activity. They strongly expressed vimentin, inhibin, CD99 and calretinin. The final diagnosis of mucinous cystadenoma associated with hyperplasia of stromal Leydig cells was made. Conclusions: Leydig cell hyperplasia belongs to the specific changes of ovarian stroma associated with pregnancy. The present case stresses that in such situation the pathologists should be aware of it and not confuse it with a tumor.
背景:妊娠期卵巢间质发生激素诱导的非肿瘤性病变,必须得到病理学家的识别,以免误以为是真正的肿瘤。病例报告:一名28岁妇女通过剖宫产产下一名健康婴儿。作为一个偶然的发现,在左侧卵巢发现一个多囊性肿瘤并切除。组织病理学符合良性粘液囊腺瘤。此外,在黏液上皮内膜下的基质内,可见密集的黏合多边形细胞群,具有丰富的嗜酸性细胞质,典型地类似于间质细胞。它们是均匀的,无异型性,伴有最小的增殖活性。它们强烈表达vimentin、抑制素、CD99和calretinin。最后诊断为粘液囊腺瘤伴间质间质细胞增生。结论:间质细胞增生属于卵巢间质与妊娠相关的特异性变化。本病例强调,在这种情况下,病理学家应该意识到这一点,不要混淆它与肿瘤。
{"title":"Mucinous Cystadenoma of the Ovary Associated with Hyperplasia of Stromal Leydig Cells in Pregnant Woman","authors":"V. Bartoš","doi":"10.21802/GMJ.2021.2.5","DOIUrl":"https://doi.org/10.21802/GMJ.2021.2.5","url":null,"abstract":"Background: The hormonally induced non-neoplastic lesions of ovarian stroma during pregnancy must be recognized by pathologist in order to avoid mistaking them for true tumors. Case report: A 28-year-old woman was delivered of a healthy infant by cesarean section. As an incidental finding, a multicystic tumor in the left ovary was found and resected. Histopathology was consistent with benign mucinous cystadenoma. In addition, within the stroma beneath the lining mucinous epithelium, a dense population of cohesive polygonal cells with abundant eosinophilic cytoplasm, typically resembling the Leydig cells, was seen. They were uniform without atypia, accompaning by minimal proliferative activity. They strongly expressed vimentin, inhibin, CD99 and calretinin. The final diagnosis of mucinous cystadenoma associated with hyperplasia of stromal Leydig cells was made. Conclusions: Leydig cell hyperplasia belongs to the specific changes of ovarian stroma associated with pregnancy. The present case stresses that in such situation the pathologists should be aware of it and not confuse it with a tumor.","PeriodicalId":12537,"journal":{"name":"Galician Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46414546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Galician Medical Journal
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