Global energy crises, limited energy resources and damage to nature in energy production have pushed humanity to use energy more efficiently and renewable energy sources. In this context, the importance of implementing energy efficiency and sustainable strategies in buildings which consumes high energy, has increased. In this study, the effect of luminaires substition with more efficient ones and electricity production by renewable energy sources on efficiency, sustainability and environment was examined on a sample education building.The calculations were made according to standards and equipment supplier data. As a result of this study, it has been found that the use of high-efficiency LED lighting instead of halogen or fluorescence luminaires in the engineering faculty building and laboratory of Hitit University, will reduce the electricity consumption by 68.2%. In addition, it has been deduced that the solar energy system to be installed on the faculty’s roof, will significantly reduce CO2 emission, and has a payback period of 5.5 years. In terms of gas emissions, a roof-mounted solar energy system is 21, 45, and 32 times less hazardous to the environment than natural gas, lignite, and fuel oil, respectively.
{"title":"Indoor Lighting Conversion Approach for Sustainable Energy Efficiency Applications in Campus Buildings: Hitit University Engineering Faculty Study","authors":"S. S. Seyitoglu, Ömer Faruk Tozlu, Emir Avcioglu","doi":"10.35378/gujs.1002669","DOIUrl":"https://doi.org/10.35378/gujs.1002669","url":null,"abstract":"Global energy crises, limited energy resources and damage to nature in energy production have pushed humanity to use energy more efficiently and renewable energy sources. In this context, the importance of implementing energy efficiency and sustainable strategies in buildings which consumes high energy, has increased. In this study, the effect of luminaires substition with more efficient ones and electricity production by renewable energy sources on efficiency, sustainability and environment was examined on a sample education building.The calculations were made according to standards and equipment supplier data. As a result of this study, it has been found that the use of high-efficiency LED lighting instead of halogen or fluorescence luminaires in the engineering faculty building and laboratory of Hitit University, will reduce the electricity consumption by 68.2%. In addition, it has been deduced that the solar energy system to be installed on the faculty’s roof, will significantly reduce CO2 emission, and has a payback period of 5.5 years. In terms of gas emissions, a roof-mounted solar energy system is 21, 45, and 32 times less hazardous to the environment than natural gas, lignite, and fuel oil, respectively.","PeriodicalId":12615,"journal":{"name":"gazi university journal of science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43138927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In the paper, we introduce the class of trigonometrically convex functions and using the Hölder, Hölder-İşcan, Power-mean and Improved power-mean integral inequality together with an identity we establish some new inequalities of Ostrowski-type for functions whose second derivatives are trigonometrically convex which is a special case of h-convex functions. Some applications for special means are also given.
{"title":"New Ostrowski Type Inequalities for Trigonometrically Convex Functions Via Classical Integrals","authors":"Şenol Demir, S. Maden","doi":"10.35378/gujs.934699","DOIUrl":"https://doi.org/10.35378/gujs.934699","url":null,"abstract":"In the paper, we introduce the class of trigonometrically convex functions and using the Hölder, Hölder-İşcan, Power-mean and Improved power-mean integral inequality together with an identity we establish some new inequalities of Ostrowski-type for functions whose second derivatives are trigonometrically convex which is a special case of h-convex functions. Some applications for special means are also given.","PeriodicalId":12615,"journal":{"name":"gazi university journal of science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49525675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In this paper, a hydraulic motor controller is designed with a fuzzy supported integral sliding mode algorithm. The hydraulic system used in the study was modeled using artificial neural networks. Ability of handling nonlinearity of systems makes sliding mode controller to be a good choose for this system. The integral sliding mode controller can supply the robustness the system against the uncertainties. The basic idea of the proposed control method is to use fuzzy logic for the adaptation of the integral sliding mode control switching gain. Such adjustment reduces the chattering that is the most problem of classical sliding mode control. The equivalent control is computed using the radial basis function neural network. Simulation results of the presented method were compared with conventional PID controller results. It proved that it is more efficient to control the hydraulic system with integral fuzzy sliding mode control using neural network.
{"title":"Integral Fuzzy Sliding Mode Controller for Hydraulic System Using Neural Network Modelling","authors":"A. Ak, Erdal Yilmaz, Sevan Katrancioglu","doi":"10.35378/gujs.979370","DOIUrl":"https://doi.org/10.35378/gujs.979370","url":null,"abstract":"In this paper, a hydraulic motor controller is designed with a fuzzy supported integral sliding mode algorithm. The hydraulic system used in the study was modeled using artificial neural networks. Ability of handling nonlinearity of systems makes sliding mode controller to be a good choose for this system. The integral sliding mode controller can supply the robustness the system against the uncertainties. The basic idea of the proposed control method is to use fuzzy logic for the adaptation of the integral sliding mode control switching gain. Such adjustment reduces the chattering that is the most problem of classical sliding mode control. The equivalent control is computed using the radial basis function neural network. Simulation results of the presented method were compared with conventional PID controller results. It proved that it is more efficient to control the hydraulic system with integral fuzzy sliding mode control using neural network.","PeriodicalId":12615,"journal":{"name":"gazi university journal of science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42511602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kübra AKSOY ÖZLER, M. L. Hidayetoğlu, Kemal Yıldırım
In this study, it was aimed to determine the effects of color hues and usage rates in interior spaces on the spatial perceptions of users. With this objective, a living space was designed in a manner that would have three different color hues (warm, neutral, and cool) and usage rates at 10%, 50%, and 100% and digital visuals were prepared. A total of 233 subjects participated in the research questionnaire and the data obtained was analyzed. In conclusion, it was determined that the living spaces which were colored at a low rate were perceived more positively according to the Semantic Differentiation Scales compared to the completely colored spaces. The spaces where warm and cool colors were used at the rate of 10% were perceived as more spacious and beautiful compared to the spaces where colors were used at the rates of 50% and 100%, whereas it was observed that when the values received were from positive to negative, they were listed in the form of 10% > 50% > 100%. Despite this, it was determined that the spaces where warm colors were used at the rates of 50% and 100% were perceived as more informal. Furthermore, it was observed that the differences in the color hues used on the walls and the usage rates were changing according to genders and professions. Accordingly, it was determined that especially females and interior architects preferred even more the spaces with warm colors having a low usage rate.
{"title":"Effect of Wall Colors and Usage Rates on The Perception of Interior Spaces","authors":"Kübra AKSOY ÖZLER, M. L. Hidayetoğlu, Kemal Yıldırım","doi":"10.35378/gujs.1120440","DOIUrl":"https://doi.org/10.35378/gujs.1120440","url":null,"abstract":"In this study, it was aimed to determine the effects of color hues and usage rates in interior spaces on the spatial perceptions of users. With this objective, a living space was designed in a manner that would have three different color hues (warm, neutral, and cool) and usage rates at 10%, 50%, and 100% and digital visuals were prepared. A total of 233 subjects participated in the research questionnaire and the data obtained was analyzed. In conclusion, it was determined that the living spaces which were colored at a low rate were perceived more positively according to the Semantic Differentiation Scales compared to the completely colored spaces. The spaces where warm and cool colors were used at the rate of 10% were perceived as more spacious and beautiful compared to the spaces where colors were used at the rates of 50% and 100%, whereas it was observed that when the values received were from positive to negative, they were listed in the form of 10% > 50% > 100%. Despite this, it was determined that the spaces where warm colors were used at the rates of 50% and 100% were perceived as more informal. Furthermore, it was observed that the differences in the color hues used on the walls and the usage rates were changing according to genders and professions. Accordingly, it was determined that especially females and interior architects preferred even more the spaces with warm colors having a low usage rate.","PeriodicalId":12615,"journal":{"name":"gazi university journal of science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46299596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In this study, robust and high-performance vector control of a rotor side converter (RSC) is performed for the stability and efficient operation doubly fed induction generator (DFIG) based on the variable speed wind turbine (VSWT). The mathematical model of the DFIG is simulated by using Matlab/Simulink. The amplitude and frequency of the voltage in the DFIG is controlled for different values of load and variable speeds. In the experimental study, a DFIG-based wind turbine system is set up in the laboratory. The field position of stator is detected from stator voltages by a phase locked loop (PLL) circuit. The rotor position is measured with an incremental encoder connected to the rotor shaft of the DFIG. The angular position of slip is calculated by the difference between the rotor and the stator field positions. The frequency and amplitude of rotor currents are determined with the angular position of slip. The space vector pulse width modulation (SVPWM) technique is used to generate the output voltages of the converter that feeds the rotor windings. In the experimental study, the rotor side converter is controlled with the DS1103 board. The prepared experiment set is tested at different operating speeds.
{"title":"Rotor Field Oriented Control of Doubly Fed Induction Generator in Wind Energy Conversion System","authors":"Z. Omac, İrfan Erdem","doi":"10.35378/gujs.987303","DOIUrl":"https://doi.org/10.35378/gujs.987303","url":null,"abstract":"In this study, robust and high-performance vector control of a rotor side converter (RSC) is performed for the stability and efficient operation doubly fed induction generator (DFIG) based on the variable speed wind turbine (VSWT). The mathematical model of the DFIG is simulated by using Matlab/Simulink. The amplitude and frequency of the voltage in the DFIG is controlled for different values of load and variable speeds. In the experimental study, a DFIG-based wind turbine system is set up in the laboratory. The field position of stator is detected from stator voltages by a phase locked loop (PLL) circuit. The rotor position is measured with an incremental encoder connected to the rotor shaft of the DFIG. The angular position of slip is calculated by the difference between the rotor and the stator field positions. The frequency and amplitude of rotor currents are determined with the angular position of slip. The space vector pulse width modulation (SVPWM) technique is used to generate the output voltages of the converter that feeds the rotor windings. In the experimental study, the rotor side converter is controlled with the DS1103 board. The prepared experiment set is tested at different operating speeds.","PeriodicalId":12615,"journal":{"name":"gazi university journal of science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48154292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Doubts about the architectural style of the Kaboud Mosque in Tabriz are related to the geometry of the plan and its special volumetric composition, which has made this building different from other examples of mosque architecture in Iran. For this reason, some scholars, following the formal origins of this mosque, have traced its roots in the art of the Ottoman region and, as a result, have introduced the architecture of the Kaboud Mosque as an imitation of Ottoman architecture. In the present study, it is assumed that the architecture of the Kaboud Mosque, despite having some similarities in the form of mosques in Ottoman, has been built according to the principles of Iranian architecture. Using a descriptive-analytical method, it seeks to answer the question of what are the geometric principles used in the architecture of Kaboud Mosque in Tabriz. The results show that the construction of the Kaboud Mosque is similar in form to some Ottoman architectural works. However, structurally, it has been created entirely based on the Iranian engineering style. The architectural style of this building, although it opened a new chapter in the design of the mosque in Iranian architecture, but could not arouse the desire of later architects to repeat its form.
{"title":"Geometric Patterns Used in the Architecture of Kaboud Mosque in Tabriz, Iran","authors":"Mahya Ghouchani, Faeze Gholizade, Hooman Sobouti","doi":"10.35378/gujs.1055129","DOIUrl":"https://doi.org/10.35378/gujs.1055129","url":null,"abstract":"Doubts about the architectural style of the Kaboud Mosque in Tabriz are related to the geometry of the plan and its special volumetric composition, which has made this building different from other examples of mosque architecture in Iran. For this reason, some scholars, following the formal origins of this mosque, have traced its roots in the art of the Ottoman region and, as a result, have introduced the architecture of the Kaboud Mosque as an imitation of Ottoman architecture. In the present study, it is assumed that the architecture of the Kaboud Mosque, despite having some similarities in the form of mosques in Ottoman, has been built according to the principles of Iranian architecture. Using a descriptive-analytical method, it seeks to answer the question of what are the geometric principles used in the architecture of Kaboud Mosque in Tabriz. The results show that the construction of the Kaboud Mosque is similar in form to some Ottoman architectural works. However, structurally, it has been created entirely based on the Iranian engineering style. The architectural style of this building, although it opened a new chapter in the design of the mosque in Iranian architecture, but could not arouse the desire of later architects to repeat its form.","PeriodicalId":12615,"journal":{"name":"gazi university journal of science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45381192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Denoising is one of the most important preprocesses in image processing. Noises in images can prevent extracting some important information stored in images. Therefore, before some implementations such as image classification, segmentation, etc., image denoising is a necessity to obtain good results. The purpose of this study is to compare the deep learning techniques and traditional techniques on denoising facial images considering two different types of noise (Gaussian and Salt&Pepper). Gaussian, Median, and Mean filters have been specified as traditional methods. For deep learning methods, deep convolutional denoising autoencoders (CDAE) structured on three different optimizers have been proposed. Both accuracy metrics and computational times have been considered to evaluate the denoising performance of proposed autoencoders, and traditional methods. The utilized standard evaluation metrics are the peak signal to noise ratio (PSNR) and structural similarity index measure (SSIM). It has been observed that overall, while the traditional methods gave results in shorter times in terms of computation times, the autoencoders performed better concerning the evaluation metrics. The CDAE based on the Adam optimizer has been shown the best results in terms of PSNR and SSIM metrics on removing both types of noise
{"title":"A Comparative Study on Denoising from Facial Images using Convolutional Autoencoder","authors":"M. Darici, Z. Erdem","doi":"10.35378/gujs.1051655","DOIUrl":"https://doi.org/10.35378/gujs.1051655","url":null,"abstract":"Denoising is one of the most important preprocesses in image processing. Noises in images can prevent extracting some important information stored in images. Therefore, before some implementations such as image classification, segmentation, etc., image denoising is a necessity to obtain good results. The purpose of this study is to compare the deep learning techniques and traditional techniques on denoising facial images considering two different types of noise (Gaussian and Salt&Pepper). Gaussian, Median, and Mean filters have been specified as traditional methods. For deep learning methods, deep convolutional denoising autoencoders (CDAE) structured on three different optimizers have been proposed. Both accuracy metrics and computational times have been considered to evaluate the denoising performance of proposed autoencoders, and traditional methods. The utilized standard evaluation metrics are the peak signal to noise ratio (PSNR) and structural similarity index measure (SSIM). It has been observed that overall, while the traditional methods gave results in shorter times in terms of computation times, the autoencoders performed better concerning the evaluation metrics. The CDAE based on the Adam optimizer has been shown the best results in terms of PSNR and SSIM metrics on removing both types of noise","PeriodicalId":12615,"journal":{"name":"gazi university journal of science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46108572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The paper explains a control method for turntable by feedback a PID controller with the traditional model reference adaptive controller (MRAC) based on MIT rule. The traditional MRAC is designed for first-order system with adjustment of two-variable parameter. However, the majority of plants, including turntable, are second order system. Traditional MRAC tracking performance for second order system is unsatisfactory. Control law for second order system along with extension from first to second order of MRAC is derived. The modified MRAC i.e., MRAC-PID controller is designed for the application of turntable. It enhanced the system’s dynamic performance. To assess the performance of the proposed controller, MATLAB/Simulink software was used. The article incorporates detailed analysis and comparison of MRAC as well as MRAC-PID controller based on MIT rule for the second order system. Several adaptive gains were chosen during simulation for verify the robustness of proposed controller. It is observed that MRAC would definitely be track the reference model but modified MRAC has better performance. Several performance indexes such as integral absolute error (IAE), integral time absolute error (ITAE) and integral square error (ISE) were employed to justify the proposed controller superiority.
{"title":"Design and Implementation of MRAC & MRAC-PID feedback for Turntable","authors":"Saibal Manna, D. Singh, Ashok Kumar Aella","doi":"10.35378/gujs.1052850","DOIUrl":"https://doi.org/10.35378/gujs.1052850","url":null,"abstract":"The paper explains a control method for turntable by feedback a PID controller with the traditional model reference adaptive controller (MRAC) based on MIT rule. The traditional MRAC is designed for first-order system with adjustment of two-variable parameter. However, the majority of plants, including turntable, are second order system. Traditional MRAC tracking performance for second order system is unsatisfactory. Control law for second order system along with extension from first to second order of MRAC is derived. The modified MRAC i.e., MRAC-PID controller is designed for the application of turntable. It enhanced the system’s dynamic performance. To assess the performance of the proposed controller, MATLAB/Simulink software was used. The article incorporates detailed analysis and comparison of MRAC as well as MRAC-PID controller based on MIT rule for the second order system. Several adaptive gains were chosen during simulation for verify the robustness of proposed controller. It is observed that MRAC would definitely be track the reference model but modified MRAC has better performance. Several performance indexes such as integral absolute error (IAE), integral time absolute error (ITAE) and integral square error (ISE) were employed to justify the proposed controller superiority.","PeriodicalId":12615,"journal":{"name":"gazi university journal of science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48469592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lumbar spinal stenosis is a disease with negative consequences and usually occurs in 3 vertebrae, disc and canal located in the lower back. In this region, the nerves in the canal can be exposed to pressure for various reasons, and diseases occur. Surgical operation is required to treat canal narrowing, and the exact location and size of the spinal stenosis is vital importance for the operation. The UNet model, which is an example of this network, can be further deeper using different deep learning networks. In this study, it is aimed to be the basis for the creation of a system that helps in the diagnosis of canal stenosis by using a deeper network. The ResUNET model, in which ResNet is used as the backbone, achieved an average IoU of 0.987. This result reveals that MR images can be used in segmentation for the diagnosis of Lumbar spinal stenosis.
{"title":"LUMBAR SPINAL STENOSIS ANALYSIS WITH DEEP LEARNING BASED DECISION SUPPORT SYSTEMS","authors":"Sinan Altun, A. Alkan","doi":"10.35378/gujs.1116423","DOIUrl":"https://doi.org/10.35378/gujs.1116423","url":null,"abstract":"Lumbar spinal stenosis is a disease with negative consequences and usually occurs in 3 vertebrae, disc and canal located in the lower back. In this region, the nerves in the canal can be exposed to pressure for various reasons, and diseases occur. Surgical operation is required to treat canal narrowing, and the exact location and size of the spinal stenosis is vital importance for the operation. The UNet model, which is an example of this network, can be further deeper using different deep learning networks. In this study, it is aimed to be the basis for the creation of a system that helps in the diagnosis of canal stenosis by using a deeper network. The ResUNET model, in which ResNet is used as the backbone, achieved an average IoU of 0.987. This result reveals that MR images can be used in segmentation for the diagnosis of Lumbar spinal stenosis.","PeriodicalId":12615,"journal":{"name":"gazi university journal of science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43776037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nickel phthalocyanine complex containing 4-(3,4-dicyanophenoxy)-3-methoxybenzoic acid group was synthesized and specified by way of FT-IR, NMR, UV/Vis procedures. The binding of PcNi complex to CT-DNA was examined via electronic absorption titration, emission titration, melting temperature, viscosity measurement, and agarose gel electrophoresis technics, respectively. The DNA interaction activity of PcNi against CT-DNA was studied by way of UV/Vi titrations, fluorescence spectra, farther by conducting melting point, viscosity procedures in the buffer of a pH 7.02. The obtained outcomes from these methods demonstrated that PcNi indicated substantial binding affinity to the DNA via intercalating by the binding constant of 1.31 x 106 m-1. Further, the interaction activity of the complex on CT-DNA was investigated by which the electrophoresis technique and this procedure indicated that PcNi complex exhibits strong binding affinity on the DNA.
合成了含有4-（3，4-二氰基苯氧基）-3-甲氧基苯甲酸基团的酞菁镍配合物，并用FT-IR、NMR、UV/Vis等方法对其进行了表征。分别采用电子吸收滴定法、发射滴定法、熔融温度法、粘度测定法和琼脂糖凝胶电泳法检测了PcNi复合物与CT-DNA的结合。用紫外/可见光谱法、荧光光谱法、熔点法、粘度法研究了PcNi对CT-DNA的DNA相互作用活性。从这些方法获得的结果表明，PcNi通过插入1.31 x 106m-1的结合常数显示出对DNA的实质性结合亲和力。此外，还研究了该复合物对CT-DNA的相互作用活性，通过电泳技术和该程序表明，PcNi复合物对DNA表现出较强的结合亲和力。
{"title":"The Study of Interaction Activity of Nickel (ll) Phthalocyanine Complex Bearing Tetra Substituted Phenoxy-3-Methoxybenzoic Acid Groups with DNA","authors":"A. Arslantaş, M. Ağırtaş","doi":"10.35378/gujs.1089316","DOIUrl":"https://doi.org/10.35378/gujs.1089316","url":null,"abstract":"Nickel phthalocyanine complex containing 4-(3,4-dicyanophenoxy)-3-methoxybenzoic acid group was synthesized and specified by way of FT-IR, NMR, UV/Vis procedures. The binding of PcNi complex to CT-DNA was examined via electronic absorption titration, emission titration, melting temperature, viscosity measurement, and agarose gel electrophoresis technics, respectively. The DNA interaction activity of PcNi against CT-DNA was studied by way of UV/Vi titrations, fluorescence spectra, farther by conducting melting point, viscosity procedures in the buffer of a pH 7.02. The obtained outcomes from these methods demonstrated that PcNi indicated substantial binding affinity to the DNA via intercalating by the binding constant of 1.31 x 106 m-1. Further, the interaction activity of the complex on CT-DNA was investigated by which the electrophoresis technique and this procedure indicated that PcNi complex exhibits strong binding affinity on the DNA.","PeriodicalId":12615,"journal":{"name":"gazi university journal of science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49514966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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