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MANAGEMENT OF LUMBOSACRAL PAIN WITH RADICULOPATHY BY EPIDURAL STEROID INJECTION IN TERTIARY CARE HOSPITAL IN DAR ES SALAAM, TANZANIA 坦桑尼亚达累斯萨拉姆三级医院通过硬膜外类固醇注射治疗伴有根神经病变的腰骶部疼痛
Pub Date : 2024-02-15 DOI: 10.36106/gjra/1501286
Kaustubh M Chauhan
Introduction:- The aim of this retrospective observational study was to compare the potential efcacy ofepidural steroid injection along with other conservative measures for relieving pain and improvingfunction in patients with lumbosacral pain with radiculopathy caused by lumbar disc herniation. The route of administration(transforaminal, caudal or translaminar) were chosen on basis of pattern of radiculopathy and mri ndings of disc herniation.Methods:- This study included 131 patients who presented with low back pain and radiculopathy due to lumbar discherniation(at levels of L4–L5 or L5–S1) diagnosed clinically and conrmed by means of MRI. 4 patients were lost to follow upremainig 127 patients at nal follow up.(127 patients)All patients were given fair trial of conservative treatment with drugs andphysiotherapy. All patients were assessed at presentation and after starting the treatment at the second week and then thirdand sixth month using the visual analogue scale (VAS) for pain and the Oswestry Disability Index (ODI) for function status.Results:- In the transforaminal group (45 patients), there was a statistically signicant improvement in the ODI scores frombefore the injection (ODI mean 62.4) to 2 weeks after the injection (ODI mean 24.4, P < 0.01), and upon follow-up at 3 months.(ODI mean 20.8, P < 0.01). 21 patients (16.5%) required 1 or 2 repeated injections, 4 (3.1%) patients underwent surgery. In theinterlaminar group (19 patients), there was a statistically signicant improvement in the ODI scores from before the injection(ODI mean 60.7) to 2 weeks after the injection (ODI mean 30.1, P < 0.01), but not upon follow-up (ODI mean 43.2, P = 0.09).5(26.3%) patients required 1 or 2 repeated injection, 2 (10.5%) patients underwent surgery and 4(21%) patients developedtransient paraparesis.In caudal group(63 patients) there was statistically signicant improvement in ODI SCROES from beforethe injection (ODI mean 39.6) to 2 weeks after the injection (ODI mean 29.6) which deteriorate at 3 months( ODI mean31.8).There was an insignicant difference (P > 0.05) between the transformainal and caudal groups in the VAS, except at thethird month (P < 0.05). Epidural steroid injection could be a preferable choice in chronic lowback and radicular Conclusion:-pain due to LDH. It has shown good short term outcomes and can be safe, cost effective and minimally invasive treatment andalternative to surgery.
导言:- 这项回顾性观察研究旨在比较硬膜外类固醇注射与其他保守措施在缓解腰椎间盘突出症引起的腰骶部疼痛并改善患者功能方面的潜在。方法:- 本研究纳入了 131 名腰椎间盘突出症(L4-L5 或 L5-S1)引起的腰背痛和根性神经病患者,这些患者经临床诊断并通过核磁共振成像。所有患者均接受了药物和物理治疗的保守治疗。所有患者均在就诊时和开始治疗后的第二周、第三和第六个月接受了评估,评估采用视觉模拟量表(VAS)和Oswestry残疾指数(ODI),前者用于评估疼痛,后者用于评估功能状况。结果:- 在经椎间孔组(45 名患者)中,从注射前(ODI 平均值为 62.4)到注射后 2 周(ODI 平均值为 24.4,P <0.01),以及 3 个月的随访(ODI 平均值为 20.8,P <0.01),ODI 评分均有显著改善。21 名患者(16.5%)需要重复注射 1 或 2 次,4 名患者(3.1%)接受了手术。在椎间孔组(19 名患者)中,从注射前(ODI 平均值为 60.7)到注射后 2 周(ODI 平均值为 30.1,P <0.01),ODI 评分均有显著改善(ODI 平均值为 43.2,P =0.09),但在随访时没有改善(ODI 平均值为 43.2,P =0.09)。5(26.3%)名患者需要重复注射 1 或 2 次,2(10.5%)名患者接受了手术,4(21%)名患者出现短暂性截瘫。在尾侧注射组(63 名患者)中,从注射前(ODI 平均值为 39.6)到注射后 2 周(ODI 平均值为 29.6),ODI SCROES 均有显著改善,但在 3 个月后(ODI 平均值为 31.8),改善程度有所减弱(P>0.05)。硬膜外类固醇注射是治疗 LDH 引起的慢性腰背痛和根性结节痛的首选方法。它具有良好的短期疗效,是一种安全、经济、微创的治疗方法,也是手术的替代疗法。
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引用次数: 0
SICKLE CELL DISEASE AND COMPLICATIONS: AN IN-DEPTH NARRATIVE EXPLORATION 镰状细胞病及并发症:深入的叙事探索
Pub Date : 2024-02-15 DOI: 10.36106/gjra/3606805
Ana Maria Aristizabal Gil
Sickle cell disease (SCD) is an inherited genetic disorder characterized by the production of abnormalhemoglobin, known as hemoglobin S. This alteration leads to the formation of sickle-shaped red bloodcells, impeding their passage through blood vessels and causing blockages, ischemia, and pain. Additionally, individuals withSCD are more susceptible to infections and vascular complications. Acute pain crises are a common manifestation of SCD,triggered by blood vessel obstruction. These crises may necessitate immediate medical intervention to alleviate pain andprevent complications. Long-term complications include chronic organ damage, such as kidney failure, lung injuries, andcardiac disorders. COVID-19 has raised additional concerns, as SCD patients may face an elevated risk of severecomplications. Hydroxyurea and blood transfusions are therapeutic strategies used to reduce pain crises and preventcomplications. Ongoing research seeks more effective therapies and comprehensive management strategies to enhance thequality of life for those living with this genetic disorder.
镰状细胞病(SCD)是一种遗传性疾病,其特征是产生异常的血红蛋白,即血红蛋白 S。这种改变会导致镰状红细胞的形成,阻碍红细胞通过血管,造成血管堵塞、缺血和疼痛。此外,镰状红细胞症患者更容易感染和出现血管并发症。急性疼痛危机是 SCD 的常见表现,由血管阻塞引发。这些危机可能需要立即进行医疗干预,以减轻疼痛和预防并发症。长期并发症包括慢性器官损伤,如肾衰竭、肺损伤和心脏病。COVID-19 引发了更多关注,因为 SCD 患者可能面临更高的严重并发症风险。羟基脲和输血是用于减轻疼痛危机和预防并发症的治疗策略。正在进行的研究旨在寻求更有效的疗法和综合管理策略,以提高这种遗传性疾病患者的生活质量。
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引用次数: 0
A RARE CASE REPORT ON AN INCIDENTAL MASSIVE RETROPERITONEAL ASCENDING COLON MESENTERIC CYST 腹膜后巨大升结肠肠系膜囊肿的罕见病例报告
Pub Date : 2024-02-15 DOI: 10.36106/gjra/3901193
T. Nulukurthi, Ch. Anjini Suvarchala Devi, V. S. R. K. N. Sree Dutta
Background: The discovery of cystic lesions within the retroperitoneal region is a rare occurrence thatpresents clinicians with the problem of a difcult diagnosis and management of the condition. Thepresent paper details the management of a case wherein a substantial cystic lesion was incidentally identied following anepisode of dengue fever during a routine abdominal scan. Case Presentation: A 24-year-old male presented to the surgicaloutpatient department (OPD) with the incidental discovery of an intra-abdominal cystic mass during an ultrasound scanconducted as part of his evaluation for dengue infection. He underwent surgery and was discharged after a successful recovery.Conclusion: Mesenteric cysts are uncommon benign abdominal lesions with a 3% risk of malignant development. Most cystsare asymptomatic and are discovered by chance or during the treatment of their problems. The mesentery of the small bowel isthe most common origin, followed by the mesocolon. A case report of a 24-year-old male with a huge abdominal mesentericretroperitoneal cyst arising from caecum and ascending colon is presented
背景:在腹膜后区域发现囊性病变是一种罕见的情况,给临床医生带来了不同cult 诊断和处理的难题。本文详细介绍了一个病例的治疗过程,该病例是在登革热发作后进行常规腹部扫描时偶然发现的实质性囊性病变。病例介绍:一名 24 岁的男性在进行登革热感染评估的超声波扫描时意外发现腹腔内囊性肿块,遂前往外科门诊部(OPD)就诊。他接受了手术治疗,术后顺利康复出院:肠系膜囊肿是一种不常见的腹部良性病变,恶变风险为 3%。大多数肠系膜囊肿没有症状,是偶然发现或在治疗过程中发现的。小肠系膜是最常见的来源,其次是结肠系膜。本病例报告了一名 24 岁男性的巨大腹腔肠系膜腹膜囊肿,囊肿源于盲肠和升结肠。
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引用次数: 0
FLOWCHART OF FREE SOFTWARE METHODOLOGY FOR ANALYSIS OF FACIAL ASYMMETRY AND FORMATION OF HISTOGRAM MAPS AS A SURGICAL GUIDE 分析面部不对称并形成直方图作为手术指南的免费软件方法流程图
Pub Date : 2024-02-15 DOI: 10.36106/gjra/2106570
Rodrigo de Faria Valle Dornelles, Nivaldo Alonso
Surgical treatment of facial asymmetry poses challenges not only in execution but also in evaluation andplanning. Image analysis methods bring advantages and disadvantages compared to subjective forms.Virtual planning technology using three-dimensional images is an alternative, though underutilized due to the cost ofcommercial software licenses. By using free software such as Blender® and CloudCompare®, students and healthcareprofessionals, including plastic surgeons, have access to an objective and effective low-cost method for pre-surgical evaluationand planning. This study established a methodology owchart for analyzing facial asymmetry and constructing a histogrammap as a surgical guide.
面部不对称的手术治疗不仅在实施方面,而且在评估和规划方面都面临挑战。使用三维图像的虚拟规划技术是一种替代方法,但由于商业软件许可证的费用而未得到充分利用。通过使用 Blender® 和 CloudCompare® 等免费软件,学生和医疗保健专业人员(包括整形外科医生)可以使用一种客观有效且成本低廉的方法进行术前评估和规划。本研究建立了一种方法论 owchart,用于分析面部不对称并构建直方图作为手术指南。
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引用次数: 0
PERCEIVED MENTAL HEALTH AND SOCIAL SUPPORT DURING PREGNANCY AMONG PRIMIGRAVIDA AND MULTIPARA MOTHERS: A COMPARATIVE STUDY 初产妇和多产妇在怀孕期间感知到的心理健康和社会支持:一项比较研究
Pub Date : 2024-02-15 DOI: 10.36106/gjra/2406413
Mehwish Naz, Harpreet Kaur
Pregnant mothers with mental health problems are less likely to care adequately for their personalneeds, to seek and receive antenatal or postnatal care, or adhere to prescribed health regimens. Socialsupport inuences health-related behaviors and can play an important role in adaptation to pregnancy. This study aimed toassess and compare the perceived mental health and social support during pregnancy among primigravida and multiparamothers. Materials: This was a ccomparative study. The accessible sample was recruited from pregnant mothers attendingOPD at community health centre in Kurali, Punjab. Total 300 pregnant mothers were selected. Out of these, 150 mothers wereprimigravida and 150 were multipara mothers who met the inclusion criteria. Perceived mental health was assessed using thekessler distress scale (k-10) and perceived social support was assessed by multidimensional scale. Results: Comparing theperceived mental health and social support scores between pregnant mothers in primigravida and multipara group, it wasfound that multiparas had more psychological distress and less social support as compared to primigravidas. There was anegative statistically signicant correlations observed between perceived mental health and perceived social support ofprimigravida and multipara mothers (r = -.454 and p= 0.00* and r =-.526 and 0.00*) respectively. Conclusion: The ndingsfrom this study suggested that multipara mothers during pregnancy are vulnerable for mental illness and perceiving scarcity ofsocial support as compared to primigravida mothers. Hence, it was suggested that high social support lowers the risk of mentalillness. Therefore, there is a need to conduct various programs by health professionals related to social support with a view tohelping reduce mental health problems among pregnant mothers.
有心理健康问题的怀孕母亲不太可能充分照顾自己的个人需求,也不太可能寻求和接受产前或产后护理,或遵守规定的保健方案。社会支持,影响着与健康相关的行为,并能在适应妊娠过程中发挥重要作用。本研究旨在评估和比较初产妇和多产妇在怀孕期间感知到的心理健康和社会支持。材料这是一项比较研究。研究从旁遮普省库拉里(Kurali)社区医疗中心接受产前检查的孕妇中抽取样本。共选取了 300 名孕妇。其中,150 名母亲为早产,150 名母亲为多胎,她们都符合纳入标准。采用凯斯勒痛苦量表(k-10)评估感知心理健康,采用多维量表评估感知社会支持。结果:比较初产妇组和多产妇组孕妈妈的心理健康感知和社会支持得分,发现多产妇比初产妇有更多的心理困扰和更少的社会支持。据统计,初产妇和多产妇的心理健康感知和社会支持感知之间存在显著的负相关(分别为 r = -.454 和 p= 0.00* 和 r =-.526 和 0.00*)。结论本研究  的结果表明,与初产妇相比,多胎妊娠母亲在怀孕期间更容易患上精神疾病,并感到社会支持匮乏。因此,高社会支持可降低患精神疾病的风险。因此,卫生专业人员有必要开展各种与社会支持相关的项目,以帮助减少孕产妇的心理健康问题。
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引用次数: 0
CASE SERIES OF BIFID TONGUE: AS AN ISOLATED ENTITY 双裂舌病例系列:作为一个孤立的实体
Pub Date : 2024-02-15 DOI: 10.36106/gjra/9607722
Ramraj Yadav, Arpit Goyal, S. Saroj, Deepak Kumar Gupta, Vishwambhar Singh, Rajesh Kumar
Period of organogenesis is very precise duration, any factor affecting this period leads to congenitalanomaly. Bid tongue is one of the congenital anomalies mostly associated with syndromic cases likeOpitz G/BBB syndrome, oral–facial– digital syndrome type I, but isolated bid tongue can also be seen rarely. Here we describethree cases of isolated bid tongue in absence of any intra oral or facial defect.
器官形成期是一个非常精确的时期,任何影响这个时期的因素都会导致先天性畸形。双d 舌是先天性畸形之一,多见于综合征病例,如奥皮茨 G/BBB 综合征、口腔-面部-数字综合征 I 型,但孤立的双d 舌也很少见。在此,我们描述了三例在没有任何口腔内或面部缺陷的情况下出现的孤立双d 舌。
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引用次数: 0
PREVALENCE OF CORONAL PULP STONES IN RELATION TO BRUXISM AND RENAL STONES: A SURVEY IN GUJARAT STATE POPULATION. 冠髓结石与磨牙症和肾结石的关系:对古吉拉特邦人口的调查。
Pub Date : 2024-02-15 DOI: 10.36106/gjra/5000990
Krushnangi Yagnik, Shraddha Chokshi
Introduction: Calcications can occur in the dental pulp as discrete bodies known as pulp stones.Etiology remains obscure. Calcication is a great enigma to an endodontist. A local or systemic conditionmay give a premonition of such a condition. Also this has been seen to vary according to the different demographic locations.Thus the purpose of my study is to investigate the prevalence of coronal pulp stones in relation to Bruxism and Renal Stones inGujarat state population. Methodology: Patients with Bruxism and Renal Stones were involved in the study. RVG of all rstmolars of each patient were recorded to check for the coronal pulp stones. The Data obtained was subjected to statisticalanalysis using SPSS Software. Result: Co-relation exists between prevalence of coronal pulp stones in patients with Bruxismand Renal Stones. Conclusion: Thus, it can be concluded that patients with bruxism and patients with renal stones, do have acorrelation with the prevalence of coronal pulp stones, in Gujarat state population.
导言:钙化(Calcications)可在牙髓中以离散体的形式出现,被称为牙髓石。病因仍不明确。对于牙髓病学家来说,钙cation 是一个巨大的谜团。局部或全身性疾病可能是这种情况的前兆。因此,我的研究旨在调查古吉拉特邦人口中冠状牙髓结石与磨牙症和肾结石的关系。研究方法研究对象为磨牙症和肾结石患者。记录每位患者所有 rstmolars 的 RVG,以检查是否存在冠髓结石。使用 SPSS 软件对获得的数据进行统计分析。结果:磨牙症和肾结石患者的牙髓冠结石发病率之间存在相关性。结论因此,可以得出结论,在古吉拉特邦的人群中,磨牙症患者和肾结石患者的冠状髓核结石发病率确实存在相关性。
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引用次数: 0
COMPARATIVE ANALYSIS OF TEAR FILM IN DIGITAL SCREEN USERS VERSUS NON-USERS. 数码屏幕使用者与非使用者泪膜的对比分析。
Pub Date : 2024-02-15 DOI: 10.36106/gjra/4700853
Kritika Kritika, Brij K Gupta, Isha Gupta, Kanav Gupta
Background- Dry eye disease is the most frequent ophthalmologic disorder seen in routine clinicalpractice. The prevalence estimates for the general population vary greatly, from 5% to 50%. It is one of themajor contributors to lower quality of life among the young population and may have an adverse effect on mental health. AimThe study aims to compare tear lm among digital screen users and non-users. This was a cros Material and Methods- ssectional study conducted on 150 patients who were divided into 2 groups. One group was of digital screen users and the otherwas of non-users. The patients were selected based on inclusion and exclusion criteria and the study was started after gettingethical clearance. A thorough history was taken and the OSDI questionnaire was lled followed by an examination on IDRA.The values of NIBUT, Interferometry, tear meniscus height, and meibomian gland loss were calculated and analysis was doneusing STATA and SPSS software. In our study, we found that the tear lm in users Findings- was not as healthy as compared tonon-users. In our study, we also found that out of 75 users, more than half of users were having a severe form of DED. It was seenthat the values of mean NIBUT, Interferometry, and tear meniscus height were lower in the user group than in non-users andusers have more meibomian gland loss in comparison to non-users. The study has a p-value of 0.001. Conclusion- The studyconcludes that the symptoms and signs of DED are more common among digital screen users than non-users. The main reasonbehind this is improper knowledge about what measures can be taken to prevent this and long continuous screen hours.
背景- 干眼症是常规临床实践中最常见的眼科疾病。据估计,干眼症在普通人群中的发病率差别很大,从 5%到 50%不等。干眼症是导致年轻人生活质量下降的主要原因之一,并可能对心理健康产生不利影响。目的 本研究旨在比较电子屏幕使用者和非使用者的泪lm。这是一项交叉材料和方法研究,150 名患者被分为两组。一组为数字屏幕使用者,另一组为非使用者。患者根据纳入和排除标准进行筛选,在获得伦理许可后开始研究。研究人员详细询问了患者的病史,填写了 OSDI 问卷 ,然后进行了 IDRA 检查。研究人员计算了 NIBUT 值、干涉测量值、泪液半月板高度和睑板腺损失,并使用 STATA 和 SPSS 软件进行了分析。在我们的研究中,我们发现,Finding- 使用者的泪液 lm 不如非使用者健康。研究还发现,在 75 名使用者中,半数以上患有严重的 DED。研究还发现,使用者组的平均睑板腺分泌量、干涉测量值和泪液半月板高度均低于非使用者,与非使用者相比,使用者的睑板腺损失更多。研究的 p 值为 0.001。结论-- 研究得出结论,数码屏幕使用者比非使用者更容易出现 DED 的症状和体征。这背后的主要原因是对采取哪些措施可以预防这种情况以及长时间连续使用屏幕的认识不足。
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引用次数: 0
INSIGHTS INTO ATRIAL FIBRILLATION: A NARRATIVE EXAMINATION OF PATHOPHYSIOLOGY AND TREATMENT MODALITIES 洞察心房颤动:病理生理学和治疗方法的叙述性研究
Pub Date : 2024-02-15 DOI: 10.36106/gjra/8106912
Cristian Fabian Triviño Rojas, Laura Steffany González Camacho
Atrial brillation (AF) management involves critical decision points inuenced by patient preferences,duration of AF, and treatment outcomes. Rhythm control is pursued within the rst year of persistent AF,and if unsuccessful or not tolerated, a shift to rate control may be considered. Recurrent AF poses challenges, with an increasedrisk in specic patient groups. Guidelines from major cardiology societies offer comprehensive recommendations, highlightingindividualized approaches for optimal outcomes. Screening for AF, particularly in high-risk populations, enables early detectionand intervention. Manifestations vary, and a timely diagnosis relies on comprehensive evaluation, including imaging andrhythm monitoring. Treatment strategies encompass lifestyle modications, anticoagulation, and antiarrhythmic drugs, withintegrated care pathways showing promise. Despite advancements, AF remains linked to adverse outcomes, emphasizing theneed for personalized management strategies and ongoing research.
心房 brillation(房颤)管理涉及关键的决策点,受患者偏好、房颤持续时间和治疗效果的影响。在持续性房颤的第一年内,,可寻求节律控制,如果不成功或不能耐受,可考虑转向心率控制。复发性房颤具有挑战性,在特定c 患者群体中风险更高。主要心脏病学会的指南提供了全面的建议,强调了个体化的最佳治疗方法。心房颤动筛查,尤其是在高危人群中,可实现早期发现和干预。心房颤动的表现各不相同,及时诊断有赖于全面的评估,包括影像学检查和心律失常监测。治疗策略包括改变生活方式c、抗凝和抗心律失常药物,综合护理路径显示出良好的前景。尽管取得了进步,心房颤动仍然与不良后果有关,这强调了个性化管理策略和持续研究的必要性。
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引用次数: 0
BIOROBOTS IN FORENSIC GENETICS- A GIFT OF TIME 法医遗传学中的生物机器人--时间的礼物
Pub Date : 2024-02-15 DOI: 10.36106/gjra/1005365
S. S, Shameena P M, Resmi G Nair
When it comes to identifying the deceased and conducting criminal investigations, forensic genetics hasbecome a crucial component of forensic science. Over the years, deoxyribonucleic acid (DNA) has cometo be regarded as the gold standard for human identication. It is imperative to employ automated tools to expedite theextraction, quantication, amplication, and production of DNA proles in order to full the increasing demand for DNAanalysis. Robotic systems boost productivity and decrease backlog. This topic covers incorporation of an emerging trend offorensic Biorobots in the medicolegal eld to the ultimate benet of society
在鉴定死者身份和进行刑事调查时,法医遗传学已成为法医学的重要组成部分。多年来,脱氧核糖核酸(DNA)已被视为鉴定人类c 的黄金标准。为了满足日益增长的 DNA 分析,必须采用自动化工具来加快 DNA 原 的提取、定量、扩 和生产。机器人系统提高了生产率,减少了积压。本专题涉及将法医生物机器人这一新兴趋势纳入法医,最终造福于社会。
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引用次数: 0
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Global journal for research analysis
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