This prospective comparative study explores the efcacy of laparoscopic hernia repair (Total Extraperitoneal Repair – TEP) versus open Lichtenstein's repair in 50 cases of unilateral inguinal hernias. Employing convenience sampling, patients were randomly assigned to undergo either technique after pre-operative preparation. Postoperative care meticulously monitored pain, bleeding, urinary retention, and wound complications. Utilizing statistical analyses, including descriptive statistics and chi-square tests, the study scrutinized outcomes based on specic parameters. Results indicated a marked reduction in postoperative pain, shorter hospital stays, and earlier return to work with TEP repair. However, TEP repair proved to be more expensive. The study's limitations include the subjective nature of pain assessment and the challenge of long-term follow-up. These ndings contribute insights into the comparative advantages and limitations of laparoscopic and open hernia repair techniques, aiding clinicians in informed decision-making.
{"title":"A COMPARATIVE ANALYSIS OF LAPAROSCOPIC HERNIA REPAIR AND OPEN LICHTENSTEIN'S HERNIA REPAIR","authors":"Koli Nikhil Vanura, A. Kumar T.","doi":"10.36106/gjra/6006090","DOIUrl":"https://doi.org/10.36106/gjra/6006090","url":null,"abstract":"This prospective comparative study explores the efcacy of laparoscopic hernia repair (Total\u0000Extraperitoneal Repair – TEP) versus open Lichtenstein's repair in 50 cases of unilateral inguinal hernias.\u0000Employing convenience sampling, patients were randomly assigned to undergo either technique after pre-operative\u0000preparation. Postoperative care meticulously monitored pain, bleeding, urinary retention, and wound complications. Utilizing\u0000statistical analyses, including descriptive statistics and chi-square tests, the study scrutinized outcomes based on specic\u0000parameters. Results indicated a marked reduction in postoperative pain, shorter hospital stays, and earlier return to work with\u0000TEP repair. However, TEP repair proved to be more expensive. The study's limitations include the subjective nature of pain\u0000assessment and the challenge of long-term follow-up. These ndings contribute insights into the comparative advantages and\u0000limitations of laparoscopic and open hernia repair techniques, aiding clinicians in informed decision-making.","PeriodicalId":12664,"journal":{"name":"Global journal for research analysis","volume":"7 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140508258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Percutaneous renal biopsy is widely used for diagnosis, prognosis, and management of nephropathies. Early identication and embolization of the involved artery aids in effective management of the vascular complications and defers the need for nephrectomy. In this study, we aimed to evaluate various vascular injuries after renal biopsy requiring interventions. Pseudoaneurysm was the most common form of arterial injury. Target vessel was identied by angiography and successful embolization was done deferring nephrectomy. Deaths occurred due to haemorrhage.
{"title":"USUAL TO UNUSUAL VASCULAR COMPLICATIONS ENCOUNTERED DURING ENDOVASCULAR MANAGEMENT OF RENAL BIOPSY COMPLICATIONS","authors":"Zoya Shaik, S. Marupaka, J. Venkateswarlu","doi":"10.36106/gjra/5107582","DOIUrl":"https://doi.org/10.36106/gjra/5107582","url":null,"abstract":"Percutaneous renal biopsy is widely used for diagnosis, prognosis, and management of nephropathies.\u0000Early identication and embolization of the involved artery aids in effective management of the vascular\u0000complications and defers the need for nephrectomy. In this study, we aimed to evaluate various vascular injuries after renal\u0000biopsy requiring interventions. Pseudoaneurysm was the most common form of arterial injury. Target vessel was identied by\u0000angiography and successful embolization was done deferring nephrectomy. Deaths occurred due to haemorrhage.","PeriodicalId":12664,"journal":{"name":"Global journal for research analysis","volume":"11 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140508283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ganapathy Sundaresan .S, Kishore . G, Lenin Prabhakaran. M.S, Balasankari Balasankari, Karthika .P, S. Kumar M
Dental anomalies are common congenital malformations which can occur as isolated ndings or part of a syndrome. This review focuses on genetic causes of abnormal tooth development and implications of these abnormalities for clinical care. These includes abnormalities due to shape size and structure of the tooth such as Microdontia, Macrodontia, Amelogenesis Imperfecta ,Anodontia, Talons cusp, Dentin dysplasia, Dentinogenesis Imperfecta.This is followed by discussion of syndromes associated with the the developmental disturbances of the tooth such as size,shape,number and structure of the tooth . Next, we review the clinical conditions abnormalities and treatment for the syndromes with abnormalities in the tooth size, shape, and form.
{"title":"SYNDROMES ASSOCIATED WITH DEVELOPMENTAL ANOMALIES OF THE TEETH-A COMPLETE LITERATURE REVIEW","authors":"Ganapathy Sundaresan .S, Kishore . G, Lenin Prabhakaran. M.S, Balasankari Balasankari, Karthika .P, S. Kumar M","doi":"10.36106/gjra/3206461","DOIUrl":"https://doi.org/10.36106/gjra/3206461","url":null,"abstract":"Dental anomalies are common congenital malformations which can occur as isolated ndings or part of\u0000a syndrome. This review focuses on genetic causes of abnormal tooth development and implications of\u0000these abnormalities for clinical care. These includes abnormalities due to shape size and structure of the tooth such as\u0000Microdontia, Macrodontia, Amelogenesis Imperfecta ,Anodontia, Talons cusp, Dentin dysplasia, Dentinogenesis\u0000Imperfecta.This is followed by discussion of syndromes associated with the the developmental disturbances of the tooth such as\u0000size,shape,number and structure of the tooth . Next, we review the clinical conditions abnormalities and treatment for the\u0000syndromes with abnormalities in the tooth size, shape, and form.","PeriodicalId":12664,"journal":{"name":"Global journal for research analysis","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140507499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: India's population growth demands effective contraception methods to reduce maternal and neonatal mortality. Limited access to contraceptives underscores the need for practical solutions. Ormeloxifene, a non-steroidal contraceptive, offers a unique approach without hormonal disruption. This study evaluates Ormeloxifene's use, focusing on continuation rates and reasons for discontinuation in diverse demographic groups. Methods: The study included 177 women aged 18-35, divided into postpartum, postabortal, and interval contraception groups. Ormeloxifene initiation details and follow-up visits were documented. Demographic, menstrual, obstetric, and medical data were collected, ensuring condentiality. Participants were evaluated for menstrual complaints, side effects, and willingness to continue. Results: Ormeloxifene demonstrated a high continuation rate (98.8% at 3 months and 94.4% at 6 months). Menstrual complaints, primarily delayed menses, were common side effects. Religion and socioeconomic status inuenced contraceptive practices. Ormeloxifene's safety and acceptability were comparable across different initiation periods. Conclusion: Ormeloxifene proved to be an acceptable and safe contraceptive option for women in postpartum, postabortal, and interval periods. Despite minor menstrual complaints, it had a high continuation rate, indicating its potential as an effective contraceptive method in diverse populations. Adequate counseling and information dissemination are crucial for managing expected side effects and ensuring user satisfaction.
{"title":"ORMELOXIFENE: UNRAVELING DURATION OF USE AND CONTINUATION TRENDS IN CONTRACEPTIVE SEEKERS","authors":"Amanat Kaur Kullar, Mohini Paul","doi":"10.36106/gjra/3406195","DOIUrl":"https://doi.org/10.36106/gjra/3406195","url":null,"abstract":"Background: India's population growth demands effective contraception methods to reduce maternal\u0000and neonatal mortality. Limited access to contraceptives underscores the need for practical solutions.\u0000Ormeloxifene, a non-steroidal contraceptive, offers a unique approach without hormonal disruption. This study evaluates\u0000Ormeloxifene's use, focusing on continuation rates and reasons for discontinuation in diverse demographic groups. Methods:\u0000The study included 177 women aged 18-35, divided into postpartum, postabortal, and interval contraception groups.\u0000Ormeloxifene initiation details and follow-up visits were documented. Demographic, menstrual, obstetric, and medical data\u0000were collected, ensuring condentiality. Participants were evaluated for menstrual complaints, side effects, and willingness to\u0000continue. Results: Ormeloxifene demonstrated a high continuation rate (98.8% at 3 months and 94.4% at 6 months). Menstrual\u0000complaints, primarily delayed menses, were common side effects. Religion and socioeconomic status inuenced contraceptive\u0000practices. Ormeloxifene's safety and acceptability were comparable across different initiation periods. Conclusion:\u0000Ormeloxifene proved to be an acceptable and safe contraceptive option for women in postpartum, postabortal, and interval\u0000periods. Despite minor menstrual complaints, it had a high continuation rate, indicating its potential as an effective\u0000contraceptive method in diverse populations. Adequate counseling and information dissemination are crucial for managing\u0000expected side effects and ensuring user satisfaction.","PeriodicalId":12664,"journal":{"name":"Global journal for research analysis","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140507195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: This research paper is to characterize mammographic and ultrasonographic features of breast lesion with FNAC correlation and to compare sensitivity of mammography with ultrasonography in diagnosing benign and malignant breast lesions. Cross-sectional study in 66 patients Materials And Methods: who were referred to the Department of Radiodiagnosis with breast lesions and having BIRADS 2 and above on imaging from January 2023 to December 2023. Our data indicate that sensitivity and specicity of ultrasound Result: was statistically signicantly greater than mammography in patients with breast lesions for the detection of breast cancer and benign lesions particularly in dense breast women. The denitive features of benign and malignant lesions were correlating with Conclusion: FNAC, so if the lesion is found to be 100% benign (BI-RADS 2 category) in USG and mammography, FNAC may be avoided. Combined USG and mammography yielded the best result and can be used as a screening modality to detect malignancy earlier and to treat the patient earlier.
{"title":"MAMMOGRAM AND ULTRASOUND EVALUATION OF BREAST LESIONS WITH FNAC CORRELATION","authors":"Dundigalla Gayathri, Nagandla Laxmi Likitha Chowdary, Sunil Kumar Reddy Bandaru, Kesidi Sravani","doi":"10.36106/gjra/6801272","DOIUrl":"https://doi.org/10.36106/gjra/6801272","url":null,"abstract":"Objectives: This research paper is to characterize mammographic and ultrasonographic features of\u0000breast lesion with FNAC correlation and to compare sensitivity of mammography with ultrasonography in\u0000diagnosing benign and malignant breast lesions. Cross-sectional study in 66 patients Materials And Methods: who were\u0000referred to the Department of Radiodiagnosis with breast lesions and having BIRADS 2 and above on imaging from January\u00002023 to December 2023. Our data indicate that sensitivity and specicity of ultrasound Result: was statistically signicantly\u0000greater than mammography in patients with breast lesions for the detection of breast cancer and benign lesions particularly in\u0000dense breast women. The denitive features of benign and malignant lesions were correlating with Conclusion: FNAC, so if the\u0000lesion is found to be 100% benign (BI-RADS 2 category) in USG and mammography, FNAC may be avoided.\u0000Combined USG and mammography yielded the best result and can be used as a screening modality to detect malignancy\u0000earlier and to treat the patient earlier.","PeriodicalId":12664,"journal":{"name":"Global journal for research analysis","volume":"48 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140506957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Intense bleeding during general anesthesia is the major limitation during ACDF surgery. It affects operative eld visibility and increases complications. Hypotensive anesthesia is preferred to improve surgical outcomes. This study aimed to compare the efcacy of Propofol and Dexmedetomidine infusion for hypotensive anesthesia in patients undergoing ACDF surgery. To compare the efcacy and safety of Objective: Dexmedetomidine and Propofol for hypotensive anesthesia in ACDF surgeries. This prospective Materials and methods: randomized trial was conducted in 60 adult patients who were scheduled for ACDF under general anesthesia. Patients were randomly divided into two groups: group P (n = 30) received Propofol infusion of 100-150mcg/kg/min and group D (n = 30) received dexmedetomidine with a loading dose of 1 mcg/kg diluted in 10 mL 0.9% saline to be infused over 10 min after induction, followed by maintenance infusion of 0.4-0.8 mcg/kg/h. The infusions were titrated to maintain mean arterial pressure (MAP) between 60 and 70 mm Hg. Hemodynamic control, Intraoperative blood loss, Quality of the surgical eld and patient recovery were recorded. In our study, the mean arterial pressure and heart rate were signi Results: cantly lower in group D throughout the surgery than in group P. Blood loss was signicantly higher in group P (615.18 ± 18.15 ml) than in group D (480.50 ± 14.50 ml). The Surgical eld visibility was comparable between the groups. The awakening time was signicantly shorter in group D than group P. In our study, we observed that both Dexmedetomidine and Propofol Conclusion: are efcacious and safe for controlled hypotension during ACDF; however, Dexmedetomidine provides better hemodynamic control and is associated with lesser degree of sedation without any signicant adverse effects.
背景：全身麻醉期间的大量出血是 ACDF 手术的主要限制因素。它影响手术，增加并发症。低血压麻醉是改善手术效果的首选。本研究旨在比较丙泊酚和右美托咪定输注用于ACDF手术患者低血压麻醉的效果。目的：比较右美托咪定和丙泊酚在ACDF手术中用于低血压麻醉的有效性和安全性。这项前瞻性材料与方法：随机试验在 60 名计划接受 ACDF 全身麻醉的成年患者中进行。患者被随机分为两组：P 组（n = 30）接受 100-150 毫克/千克/分钟的丙泊酚输注，D 组（n = 30）接受右美托咪定输注，负荷剂量为 1 毫克/千克，用 10 毫升 0.9% 生理盐水稀释，在诱导后 10 分钟内输注，随后维持输注 0.4-0.8 毫克/千克/小时。输注量经过滴定，以将平均动脉压（MAP）维持在 60 至 70 毫米汞柱之间。对血流动力学控制、术中失血量、手术质量 eld 和患者恢复情况进行了记录。在我们的研究中，D组的平均动脉压和心率显著低于D组：cantly lower in group D throughout the surgery than group P. Blood loss was signicantly higher in group P (615.18 ± 18.15 ml) than group D (480.50 ± 14.50 ml).两组的手术 eld 可见度相当。在我们的研究中，我们观察到右美托咪定和丙泊酚对于控制 ACDF 期间的低血压都是有效cacious 和安全的；然而，右美托咪定能提供更好的血流动力学控制，并且镇静程度较低，没有任何明显cant 的不良反应。
{"title":"COMPARATIVE EVALUATION OF DEXMEDETOMIDINE AND PROPOFOL INFUSION FOR HYPOTENSIVE ANESTHESIA DURING ACDF SURGERY: A PROSPECTIVE RANDOMIZED TRIAL","authors":"Akanksha Ratanpal, Abhinav Bishnoi, Sumeet Kumar","doi":"10.36106/gjra7900723","DOIUrl":"https://doi.org/10.36106/gjra7900723","url":null,"abstract":"Background: Intense bleeding during general anesthesia is the major limitation during ACDF surgery. It\u0000affects operative eld visibility and increases complications. Hypotensive anesthesia is preferred to\u0000improve surgical outcomes. This study aimed to compare the efcacy of Propofol and Dexmedetomidine infusion for\u0000hypotensive anesthesia in patients undergoing ACDF surgery. To compare the efcacy and safety of Objective:\u0000Dexmedetomidine and Propofol for hypotensive anesthesia in ACDF surgeries. This prospective Materials and methods:\u0000randomized trial was conducted in 60 adult patients who were scheduled for ACDF under general anesthesia. Patients were\u0000randomly divided into two groups: group P (n = 30) received Propofol infusion of 100-150mcg/kg/min and group D (n = 30)\u0000received dexmedetomidine with a loading dose of 1 mcg/kg diluted in 10 mL 0.9% saline to be infused over 10 min after\u0000induction, followed by maintenance infusion of 0.4-0.8 mcg/kg/h. The infusions were titrated to maintain mean arterial pressure\u0000(MAP) between 60 and 70 mm Hg. Hemodynamic control, Intraoperative blood loss, Quality of the surgical eld and patient recovery were recorded. In our study, the mean arterial pressure and heart rate were signi Results: cantly lower in group D\u0000throughout the surgery than in group P. Blood loss was signicantly higher in group P (615.18 ± 18.15 ml) than in group D (480.50\u0000± 14.50 ml). The Surgical eld visibility was comparable between the groups. The awakening time was signicantly shorter in\u0000group D than group P. In our study, we observed that both Dexmedetomidine and Propofol Conclusion: are efcacious and safe\u0000for controlled hypotension during ACDF; however, Dexmedetomidine provides better hemodynamic control and is associated\u0000with lesser degree of sedation without any signicant adverse effects.","PeriodicalId":12664,"journal":{"name":"Global journal for research analysis","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140506959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives Fire safety is of paramount importance in healthcare settings, particularly in clinical laboratories where hazardous substances, ammable materials, and complex equipment are frequently present. Knowledge and practices of health care workers about re safety prevention is essential to ensure the well-being of patients, staff, and the preservation of critical healthcare services. Material & Methods A cross-sectional study was carried out in clinical biochemistry laboratory of Safdarjung Hospital, New Delhi, during from April 2023 to August 2023. Study participants included the doctors, paramedical technical staff and group IV people. A questionnaire with close ended and open ended questions was used for assessment. The data was tabulated in Microsoft MS-Excel data sheet and analysis was done using SPSS 27 version of statistical software. Categorical variables were presented as number, percentage and median. Qualitative variables were compared using Chi-Square test and quantitative variables using Kruskal Wallis test. For statistical signicance, p value of less than 0.05 was considered statistically signicant. 63 HCWs Results participated in the study which gave a 100% response rate. Most of the participants were Doctors (42.86%) and Laboratory technicians (44.44%) with variable years of work experience ranging from <1 year to >9 years. The results indicate that participants have a mean knowledge score of 7.94 ± 1.4 and median of 8 whereas the mean practice score was 7.24 ± 1.28 with a median of 7 towards re safety. Conclusion: The present hospital based study revealed that the majority of healthcare workers had signicant knowledge about re safety but still considering the important role of every employee in a re accident, there is need to give re safety training to all health care workers at timely intervals.
{"title":"ASSESSMENT OF KNOWLEDGE & PRACTICES ON FIRE SAFETY AMONG HEALTH CARE PROFESSIONALS IN CLINICAL LABORATORY OF TERTIARY CARE HOSPITAL IN NORTH INDIA - A CROSS SECTIONAL STUDY","authors":"S. Suneja","doi":"10.36106/gjra/2401001","DOIUrl":"https://doi.org/10.36106/gjra/2401001","url":null,"abstract":"Objectives Fire safety is of paramount importance in healthcare settings, particularly in clinical\u0000laboratories where hazardous substances, ammable materials, and complex equipment are frequently\u0000present. Knowledge and practices of health care workers about re safety prevention is essential to ensure the well-being of\u0000patients, staff, and the preservation of critical healthcare services. Material & Methods A cross-sectional study was carried out\u0000in clinical biochemistry laboratory of Safdarjung Hospital, New Delhi, during from April 2023 to August 2023. Study participants\u0000included the doctors, paramedical technical staff and group IV people. A questionnaire with close ended and open ended\u0000questions was used for assessment. The data was tabulated in Microsoft MS-Excel data sheet and analysis was done using\u0000SPSS 27 version of statistical software. Categorical variables were presented as number, percentage and median. Qualitative\u0000variables were compared using Chi-Square test and quantitative variables using Kruskal Wallis test. For statistical\u0000signicance, p value of less than 0.05 was considered statistically signicant. 63 HCWs Results participated in the study which\u0000gave a 100% response rate. Most of the participants were Doctors (42.86%) and Laboratory technicians (44.44%) with variable\u0000years of work experience ranging from <1 year to >9 years. The results indicate that participants have a mean knowledge\u0000score of 7.94 ± 1.4 and median of 8 whereas the mean practice score was 7.24 ± 1.28 with a median of 7 towards re safety.\u0000Conclusion: The present hospital based study revealed that the majority of healthcare workers had signicant knowledge\u0000about re safety but still considering the important role of every employee in a re accident, there is need to give re safety\u0000training to all health care workers at timely intervals.","PeriodicalId":12664,"journal":{"name":"Global journal for research analysis","volume":"47 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140506960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Dexmedetomidine is an selective alpha-2-receptor agonist.Various studies have been done to describe the effects of dexmedetomidine as an additive to local anaesthetics in peripheral nerve blocks.With the use of ultrasound guidance axillary brachial plexus block has been easier with reduced drug dosage and with lesser complications. Objectives: To compare the effects of addition of dexmedetomidine with 0.75% ropivacaine for axillary brachial plexus block in reference to onset of sensory and motor block and duration of analgesia. Methods: 60 patients of ASA grade I and II posted for forearm and hand surgeries were allocated randomly into two groups of 30 each,Group R will receive 0.75% ropivacaine 20ml + Nacl 0.9%(1ml) Group D will receive 0.75% ropivacaine 20ml + dexmedetomidine 1ml(100µg).Under ultrasound guidance axillary block was administered.Onset of sensory block was assessed by pin prick method,modied bromage scale was used to assess the motor block,patients would be assessed post operatively for the duration of sensory and motor blockade. present study showed that onset of sensory and motor blocks was signicantly fast Results: er in group D as compared to group R.Also duration of motor block and duration of analgesia was prolonged in group D as compared to group R. No statistically signicant changes in intraoperative MAP and HR,BP, spo among two groups. It was concluded 2 Conclusion: that addition of dexmedetomidine(100µg) to 0.75% ropivacaine shortens the sensory and motor onset time, with increased duration of analgesia and motor blockade when used for axillary brachial plexus block under ultrasound guidance without any adverse effects.
{"title":"A COMPARATIVE STUDY TO KNOW THE EFFECTS OF DEXMEDETOMIDINE AS AN ADJUVANT WITH 0.75% ROPIVACAINE FOR ULTRASOUND GUIDED AXILLARY BRACHIAL PLEXUS BLOCK FOR FOREARM AND HAND SURGERIES","authors":"Prajwal Patel H S, Bhavyashree G Y, Sarvesh B","doi":"10.36106/gjra/0307438","DOIUrl":"https://doi.org/10.36106/gjra/0307438","url":null,"abstract":"Background: Dexmedetomidine is an selective alpha-2-receptor agonist.Various studies have been\u0000done to describe the effects of dexmedetomidine as an additive to local anaesthetics in peripheral nerve\u0000blocks.With the use of ultrasound guidance axillary brachial plexus block has been easier with reduced drug dosage and with\u0000lesser complications. Objectives: To compare the effects of addition of dexmedetomidine with 0.75% ropivacaine for axillary\u0000brachial plexus block in reference to onset of sensory and motor block and duration of analgesia. Methods: 60 patients of ASA\u0000grade I and II posted for forearm and hand surgeries were allocated randomly into two groups of 30 each,Group R will receive\u00000.75% ropivacaine 20ml + Nacl 0.9%(1ml) Group D will receive 0.75% ropivacaine 20ml + dexmedetomidine 1ml(100µg).Under\u0000ultrasound guidance axillary block was administered.Onset of sensory block was assessed by pin prick method,modied\u0000bromage scale was used to assess the motor block,patients would be assessed post operatively for the duration of sensory and\u0000motor blockade. present study showed that onset of sensory and motor blocks was signicantly fast Results: er in group D as\u0000compared to group R.Also duration of motor block and duration of analgesia was prolonged in group D as compared to group\u0000R. No statistically signicant changes in intraoperative MAP and HR,BP, spo among two groups. It was concluded 2 Conclusion:\u0000that addition of dexmedetomidine(100µg) to 0.75% ropivacaine shortens the sensory and motor onset time, with increased\u0000duration of analgesia and motor blockade when used for axillary brachial plexus block under ultrasound guidance without\u0000any adverse effects.","PeriodicalId":12664,"journal":{"name":"Global journal for research analysis","volume":"15 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140507534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background and Objective: Periodontitis is a highly prevalent disease, and it affects approximately 10.5% to 12% of the world's population. Tobacco smoking adversely affects periodontal health. ALP is an essential enzyme, as it is part of the normal turnover of periodontal ligament and bone homeostasis. Saliva has many advantages as a diagnostic media. With this background this study was undertaken to evaluate Serum and Salivary Alkaline phosphatase level in tobacco cigarette smokers with chronic periodontitis. Methods: A total sample size of 40 subjects with age range of 25-65 years were included and were divided into 2 groups. Group I included 20 male healthy never smokers as control group and Group II included 20 male subjects with the habit of tobacco cigarette smoking using more than 5 cigarettes per day with onset of minimum six months duration and above as study group. Alkaline phosphatase level in serum and saliva was estimated. The obtained data was subjected to statistical analysis using Mann Whitney test and Spearman's correlation test. Results: It was found that Serum ALP was higher than Salivary ALP and there was a signicant correlation between Serum ALP and Salivary ALP in Group I (Control group) and Group II (Study group). Serum ALP and Salivary ALP were both increased in Group II (Study group) compared to healthy controls. In Group II (Study group) with an increase in number of cigarettes smoked and duration of smoking there was an increase in both Serum ALP and Salivary ALP. In Group II (Study group) Serum ALP and Salivary ALP were higher in generalized periodontitis than localized periodontitis indicating the severity of chronic periodontitis. Conclusion: We therefore recommend salivary ALP as an early potential biomarker in tobacco cigarette smokers with chronic periodontitis for diagnosis, monitoring the disease progression, prognosis and treatment outcome.
背景和目的：牙周炎是一种高发疾病，全球约有 10.5% 至 12% 的人患有这种疾病。吸烟会对牙周健康产生不利影响。ALP 是一种重要的酶，因为它是牙周韧带和骨平衡正常周转的一部分。唾液作为诊断介质有很多优点。在此背景下，本研究对患有慢性牙周炎的烟草烟民的血清和唾液碱性磷酸酶水平进行了评估。研究方法研究对象共 40 名，年龄在 25-65 岁之间，分为两组。第一组包括 20 名从不吸烟的健康男性受试者，作为对照组；第二组包括 20 名有吸烟习惯的男性受试者，作为研究组。对血清和唾液中的碱性磷酸酶水平进行了估计。采用曼-惠特尼检验（Mann Whitney test）和斯皮尔曼相关检验（Spearman's correlation test）对所得数据进行统计分析：结果发现，在第一组（对照组）和第二组（研究组）中，血清 ALP 高于唾液 ALP，并且血清 ALP 和唾液 ALP 之间存在显著的。与健康对照组相比，第二组（研究组）的血清 ALP 和唾液 ALP 均升高。在第二组（研究组）中，随着吸烟数量的增加和吸烟时间的延长，血清 ALP 和唾液 ALP 都有所增加。在第二组（研究组）中，全身性牙周炎患者的血清 ALP 和唾液 ALP 均高于局部性牙周炎患者，这表明慢性牙周炎的严重程度。结论：因此，我们建议将唾液 ALP 作为慢性牙周炎吸烟者的早期潜在生物标志物，用于诊断、监测疾病进展、预后和治疗效果。
{"title":"EVALUATION OF SERUM AND SALIVARY ALKALINE PHOSPHATASE LEVEL IN TOBACCO CIGARETTE SMOKERS WITH CHRONIC PERIODONTITIS","authors":"Suganya Suganya, Maria Priscilla David, Indira Ap","doi":"10.36106/gjra/7800859","DOIUrl":"https://doi.org/10.36106/gjra/7800859","url":null,"abstract":"Background and Objective: Periodontitis is a highly prevalent disease, and it affects approximately\u000010.5% to 12% of the world's population. Tobacco smoking adversely affects periodontal health. ALP is an\u0000essential enzyme, as it is part of the normal turnover of periodontal ligament and bone homeostasis. Saliva has many\u0000advantages as a diagnostic media. With this background this study was undertaken to evaluate Serum and Salivary Alkaline\u0000phosphatase level in tobacco cigarette smokers with chronic periodontitis. Methods: A total sample size of 40 subjects with age\u0000range of 25-65 years were included and were divided into 2 groups. Group I included 20 male healthy never smokers as control\u0000group and Group II included 20 male subjects with the habit of tobacco cigarette smoking using more than 5 cigarettes per day\u0000with onset of minimum six months duration and above as study group. Alkaline phosphatase level in serum and saliva was\u0000estimated. The obtained data was subjected to statistical analysis using Mann Whitney test and Spearman's correlation test.\u0000Results: It was found that Serum ALP was higher than Salivary ALP and there was a signicant correlation between Serum ALP\u0000and Salivary ALP in Group I (Control group) and Group II (Study group). Serum ALP and Salivary ALP were both increased in\u0000Group II (Study group) compared to healthy controls. In Group II (Study group) with an increase in number of cigarettes smoked\u0000and duration of smoking there was an increase in both Serum ALP and Salivary ALP. In Group II (Study group) Serum ALP and\u0000Salivary ALP were higher in generalized periodontitis than localized periodontitis indicating the severity of chronic\u0000periodontitis. Conclusion: We therefore recommend salivary ALP as an early potential biomarker in tobacco cigarette smokers\u0000with chronic periodontitis for diagnosis, monitoring the disease progression, prognosis and treatment outcome.","PeriodicalId":12664,"journal":{"name":"Global journal for research analysis","volume":"58 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140507025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In the world of information technology, cloud computing has become a paradigm-shifting phenomenon that is completely changing how people and enterprises access, store, and utilize data. The paper offers a thorough analysis of the expansion, fundamental ideas, and applications of cloud computing. The paper starts off by reviewing the evolution of cloud computing historically before diving into the basic service models (IaaS, PaaS, and SaaS) and deployment structures (public, private, and hybrid) that dene the cloud environment. The paper also covers the underlying technologies, such as virtualization, containerization, and distributed computing, that enable scalable, exible, and reasonably priced cloud environments. An outline of security concerns in the context of the cloud, such as data encryption, identity management, and regulatory compliance, claries the challenges and solutions to protecting data in the cloud. The study also looks at advancements in the eld, highlighting how serverless designs, edge computing, and articial intelligence integration may affect cloud computing in the future. The abstract concludes by outlining the real-world implications of cloud adoption, including how it will impact resource management, business models, and IT infrastructure as a whole.
{"title":"A BRIEF OVERVIEW OF CLOUD COMPUTING","authors":"Nandini Karnakota, Algubelly Yashwanth Reddy","doi":"10.36106/gjra/6003461","DOIUrl":"https://doi.org/10.36106/gjra/6003461","url":null,"abstract":"In the world of information technology, cloud computing has become a paradigm-shifting phenomenon\u0000that is completely changing how people and enterprises access, store, and utilize data. The paper offers\u0000a thorough analysis of the expansion, fundamental ideas, and applications of cloud computing. The paper starts off by\u0000reviewing the evolution of cloud computing historically before diving into the basic service models (IaaS, PaaS, and SaaS) and\u0000deployment structures (public, private, and hybrid) that dene the cloud environment. The paper also covers the underlying\u0000technologies, such as virtualization, containerization, and distributed computing, that enable scalable, exible, and\u0000reasonably priced cloud environments. An outline of security concerns in the context of the cloud, such as data encryption,\u0000identity management, and regulatory compliance, claries the challenges and solutions to protecting data in the cloud. The\u0000study also looks at advancements in the eld, highlighting how serverless designs, edge computing, and articial intelligence\u0000integration may affect cloud computing in the future. The abstract concludes by outlining the real-world implications of cloud\u0000adoption, including how it will impact resource management, business models, and IT infrastructure as a whole.","PeriodicalId":12664,"journal":{"name":"Global journal for research analysis","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140506844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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