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Effect of Fermented Barley Fiber on Accumulation of Liver Lipids in Rats 发酵大麦纤维对大鼠肝脏脂质积累的影响
Pub Date : 2003-12-31 DOI: 10.11217/JJDF1997.7.81
Miki Umeki, Fumiko Ando, T. Iwahashi, Hideki Hokazono, Kei Hayashi, T. Omori, S. Mochizuki
We investigated that effects of fermented barley fiber (FBF) prepared from barley shochu lees, which was produced in manufacturing barley shochu, on lipid metabolism in rats. FBF contains about 50% of dietary fiber. The components of dietary fiber were hemicellulose, cellulose and lignin. Rats were fed on a relatively high-fat diet which contains 10% of lard, and 5% or 10% of FBF. FBF did not affect the levels of serum lipids. However, the concentrations of total lipids, triacylglycerol, and cholesterol in the liver were decreased by fed a FBF-containing diet. In another experiment, we fed a diet containing 20% of FBF with 1 % of orotic acid to rats. FBF prevented the accumulation of lipids in the liver and normalized the levels of serum lipids induced by orotic acid. From these results FBF was considered to possess the improvement effects on the accumulation of lipids in the liver.
以大麦烧酒为原料,研究了发酵大麦纤维对大鼠脂质代谢的影响。FBF含有约50%的膳食纤维。膳食纤维的主要成分为半纤维素、纤维素和木质素。大鼠被喂食相对高脂肪的食物,其中含有10%的猪油和5%或10%的FBF。FBF对血脂水平无影响。然而,肝脏中总脂、甘油三酯和胆固醇的浓度在饲喂含fbf的饲料后有所降低。在另一个实验中,我们给大鼠喂食含有20% FBF和1%乳香酸的日粮。FBF可防止肝脏脂质积聚,使由山茱萸酸引起的血清脂质水平正常化。从这些结果来看,FBF被认为具有改善肝脏脂质积累的作用。
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引用次数: 0
Significance of Cecectomized Rats in Nutritional Studies 切除盲肠大鼠在营养学研究中的意义
Pub Date : 2003-06-30 DOI: 10.11217/JJDF1997.7.1
E. Sakaguchi
Rats have an enlarged cecum to be considered as an adaptive structure to variable food quality. The cecum plays an important role to utilize indigestible and fermentable food materials in the rat. Cecectomy results in faster transit of digesta connecting lower digestibilities of food components in the rat. The response of the transit and retention of digesta to the feeding of indigestible food materials is similar to that in human, where the inverse response is often recognized in normal rats, suggesting that cecectomized rats are useful in the study concerning digesta movement in the gut. Some of nutritional and physiological effects of dietary fiber and fermentable food components are extinguished by cecectomy. Some inverse results are obtained in the rats with or without cecum in the nutritional and physiological studies. Fermentation in the large gut is modified largely by cecectomy. Although the cecectomized rat has some possibilities as a useful experimental animal, there is a limitation to use the cecectomized rat as an experimental animal in the study of the function of fermentable food materials. Further comparative studies are needed in the functions of the digestive tract between human and the cecectomized rat for the strict qualification of the usefulness in human nutrition studies.
大鼠的盲肠肿大被认为是一种适应食物质量变化的结构。盲肠对大鼠体内不易消化和可发酵的食物物质的利用起着重要的作用。盲肠切除术导致大鼠的食糜运输更快,从而降低食物成分的消化率。消化液的转运和滞留对喂食不消化食物的反应与人类相似,在正常大鼠中经常发现相反的反应,这表明切除盲肠的大鼠在肠道消化液运动的研究中是有用的。盲肠切除术使膳食纤维和可发酵食品成分的一些营养和生理作用消失。在有盲肠和无盲肠大鼠的营养和生理研究中,得到了一些相反的结果。大肠的发酵在很大程度上因盲肠切除术而改变。虽然去盲肠大鼠作为一种有用的实验动物具有一定的可能性,但将去盲肠大鼠作为实验动物用于发酵食品原料功能的研究仍存在一定的局限性。为了严格确定其在人类营养学研究中的应用价值,还需要对人与切除大鼠消化道功能进行进一步的比较研究。
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引用次数: 0
Effect of Oatmeal cookies supplementation on serum cholesterol levels in Japanese men with boundary and mild hypercholesterolemia: Evaluation of Efficacy and Safety 补充燕麦饼干对日本边缘性和轻度高胆固醇血症男性血清胆固醇水平的影响:有效性和安全性评价
Pub Date : 2003-06-30 DOI: 10.11217/JJDF1997.7.26
S. Aoe, Y. Itagaki, Fumi Hatamoto, K. Ishii, Taishi Oda, Yutaka Suzuki, Y. Toba, T. Fujita, S. Kinoshita, T. Uchida, Isao Takehara, A. Kondo
given the test oatmeal cookies containing oatmeal at 30 g/4 pieces, and group C was given the same cookies containing oatmeal at 45 g/4 pieces, once a day for 12 weeks, respectively. These results were as follows: The serum total cholesterol level for the group C with boundary hypercholesterolemia decreased with a significant difference in comparison with the groups of A and C (p<0.05). There were no abnormal hematological changes , no abnormal level of physiochemical substances in blood, and clinical changes which were indicated any adverse reactions in the groups
给予含有30 g/4片燕麦片的测试燕麦饼干,C组给予含有45 g/4片燕麦片的相同饼干,每天一次,连续12周。结果表明:边界型高胆固醇血症C组血清总胆固醇水平降低,与a、C组比较差异有统计学意义(p<0.05);两组患者均未见血液学异常、血液理化物质异常及临床变化,均未见不良反应发生
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引用次数: 2
Contents and Heat-moisture Treatment Effect of Resistant Starch in High Amylose Wheat Starch 高直链小麦淀粉中抗性淀粉含量及热湿处理效果研究
Pub Date : 2003-06-30 DOI: 10.11217/JJDF1997.7.20
Mizuho Taniguti, Risa Aiuchi, J. Niwa, M. Yamamori, S. Fujita
We determined the resistant starch (RS) content of high amylose wheat (HAW) which was recently crossbred in Japan. By the crossbreeding, the endosperm starch content of HAW was decreased about 20% in comparison with that of normal wheat. HAW contained 1.3% of RS in the starch, and the content was six times higher than that of normal wheat starch. After heat-moisture treatment the RS content of normal wheat and HAW starch were 0.5 and 2.7%, respectively. The RS content of HAW was doubled of untreated one. In case of corn starch after heat-moisture treatment, the RS content of two type of high amylose corn, HAC and A632 increased to 26.2% and 2.7%, respectively. The RS of normal corn starch was scarcely contained. From the results, the heat-moisture treatment may be able to increase the RS content of wheat, although the treatment of wheat starch was not effective as that of corn starch.
测定了日本新选育的高直链淀粉小麦(HAW)的抗性淀粉(RS)含量。经杂交,小麦胚乳淀粉含量比普通小麦降低约20%。小麦小麦淀粉中RS含量为1.3%,是普通小麦淀粉的6倍。热湿处理后,普通小麦和HAW淀粉的RS含量分别为0.5%和2.7%。HAW的RS含量是未经处理的2倍。对热湿处理后的玉米淀粉,两种高直链淀粉品种HAC和A632的RS含量分别提高到26.2%和2.7%。普通玉米淀粉的RS几乎不含。结果表明,热湿处理可以提高小麦的RS含量,但小麦淀粉的处理效果不如玉米淀粉。
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引用次数: 3
Definition, classification, and comprehensive technical terms of dietary fiber in Japan 日本膳食纤维的定义、分类及综合技术术语
Pub Date : 2003-06-30 DOI: 10.11217/JJDF1997.7.39
S. Kiriyama, S. Ikegami, K. Ebihara, S. Innami, Yoko Katayama, F. Takehisa
1972年,Trowell1)に よ り生理的意義 を含ませ た概 念 として"Dietary fiber"が 登場 した。これはHipsley2) が1953年 に用いた用語 と同じであるが,生 理的意味 を 含 ませた点で異なっている。これにより従来漠然とし て 用 い られ てい た"Fiber"や 分析 上 の慣 用 語 の "C rude fiber"と は明確に区別 され,こ の定義 に含 ま れる物質は1929年 にMcCanceとLawrenceら3)に より, 「利用で きない炭水化物」 と呼ばれた もの と同 じであ ると考 えられた。 1976年,Trowellら 英 国の研 究者 グル ープ4)は, Trowell1)がDietary fiberを 最初 に定義 した当時 (1972年),ペ クチ ンやグアーガムのような粘性のある 貯蔵 多糖類は,人 間の消化酵素により加水分解 されな い ということを考慮 しなかったと述べ,こ れらの物質 はその生理作用か ら見て当然Dietary fiberに含 まれな ければならないと し,定 義の修正 を行い.,「人間の消 化管酵素 によって加水分解 されない植物の多糖類 とリ グニン」 とした。 さらに,研 究の進展 と共 に,生 理的意義 を有 す る 種々の難消化性成分 が発見 され,Trowellら4)の 修正 定義ではお さまらないようになってきた。それに伴い, 個人や機関 により定義の提案あるいは修正 が行われて い る(表1)。 甲殻類 に含まれ,そ れ らか ら分離 され たキチ ン,キ トサンに生理効果が認め られたことより, 植物性起源に限定せず,動 物性起源 も含めるという意 見,ま た,難 消化性 多糖類の部分加水解物や合成多糖 類(ポ リデキス トロース)に も生理効果 が認め られ, これ らを含めるとい う提案などがある。 さらに レジス タン トスターチ(Resistant starch)や 難消化性 デキス トリンなどの他,最 近では難消化性のオ リゴ糖類 も含 め るような提案 も出 されている。 定量法 との関係 か ら,Dietary fiberの定義 を考 える べ きとい う意見やそれに反対す る意見,あ るいは拡大 すべきという意見,さ らには,Dietary fiberという用 語の使用への問題提起 さえ出 されている。このように, 今 日Dietary fiberの定義 ・用語および構成成分につい
1972年,Trowell1),作为包含生理意义的基本理念“Dietary fiber”登场。这与Hipsley2)在1953年使用的术语相同,但不同的是包含了生物意义。根据这个以前模糊被用的"Fiber"和分析上的惯用语的"C rude Fiber"被明确的区别,这个定义包含的物质在1929年二McCance和Lawrence等3)认为与“不可利用的碳水化合物”相同。1976年,Trowell等英国的研究人员4)说,Trowell1)最初定义Dietary fiber时(1972年),白丁和口香糖等粘性储存多糖类不会被人之间的消化酶水解从生理作用来看,这些物质当然不应该包含在Dietary fiber中,因此修改了定义。不被水解的植物多糖类和木质素。”并且,随着研究的进展,发现了各种具有生物意义的难消化性成分,Trowell等人4)的修正定义已经不能结束了。与此同时,根据个人和机关对定义进行提案或修正(表1)。甲壳类中含有从它们中分离出来的甲壳素和甲壳素具有生理效果,意思是不限定植物性起源,也包括动物性起源。另外,难消化性多糖类的部分水解物和合成多糖类(聚脂多糖)也有生理效果,有包含这些的提案等。此外,还提出了除含有抗碳水化合物和淀粉(Resistant starch)以及难消化性的聚糖外,最近还含有难消化性的聚糖。有人认为应该根据定量法的关系来考虑Dietary fiber的定义,有人认为应该扩大范围,还有人认为Dietary fiber的用法甚至对词语的使用提出了问题。如上所述,关于Dietary光纤的定义、术语及构成成分
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引用次数: 2
In vitro the Antioxidant Activity of Lignophenol from Beech (Fagus crenata Blume) and Hinoki (Cryptomeria japonica D.Don) 山毛榉(Fagus crenata Blume)和红木(Cryptomeria japonica D.Don)木质素酚的体外抗氧化活性研究
Pub Date : 2003-06-30 DOI: 10.11217/JJDF1997.7.13
Shuzo Fujita, Eriko Ohmae, M. Funaoka
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引用次数: 8
Effects of Polydextrose on Habitual Constipation with Melanosis Coli 聚葡萄糖对大肠黑素病习惯性便秘的影响
Pub Date : 2002-12-31 DOI: 10.11217/JJDF1997.6.55
T. Matsuike, Yasumoto Suzuki, H. Nozawa, H. Nishino, M. Matsushima, Y. Mori
Effects of Polydextrose on Habitual Constipation with Melanosis Coli Tsuneo MATSUIKE1, Yasumoto SUZUKI1 , Hiroshi NOZAWA1, Haruo NISHINO1, Makoto MATSUSHIMA1 , and Yutaka MORI2 1 Coro-proctlogy center, Matsushima Hospital , 2 National Higashi-Utsunomiya Hospital Polydextrose has been reported to promote bowel elimination . The clinical efficacy of polydextrose administered at a daily dose of 7g for 30 days was examined in 23 patients with habitual constipation and melanosis coli found by total colonoscopy. After the start of treatment with polydextrose , 13(56.5%) of the 23 patients noted improvement in constipation (dyschezia). The stool consisitency of stools improved in 17 (85 .0%) of 20 patients having had hard stools . The frequency of defecation increased in 13 (81 .3%) of 16 patients who of fecal properties . After the use of polydextrose for 30 days, the effects of polydextrose was noted in 20(87 .0%) of the 23 patients in total as (1) improvement in constipation, (2) increased frequency of defecation , (3) softened the stool consisitency, (4) improvement in other bowel symptoms , or (5) reduced laxative dose, or two or more of those. These results indicated a clinical effects of polydextrose for the treatment of habitual constipation in patients with melanosis coli .
聚葡萄糖对大肠黑素病习惯性便秘的作用Tsuneo MATSUIKE1, Yasumoto SUZUKI1, Hiroshi NOZAWA1, Haruo NISHINO1, Makoto Matsushima a1, Yutaka MORI2 1松岛医院泌尿外科中心,2国立东宇都宫医院已有报道称聚葡萄糖能促进肠道消除。对23例经全结肠镜检查发现的习惯性便秘和大肠黑素病患者,每日给药7g,连用30 d观察聚葡萄糖的临床疗效。开始用聚葡萄糖治疗后,23例患者中有13例(56.5%)便秘(运动障碍)改善。20例硬便患者中有17例(85.0%)大便一致性改善。16例有大便特征的患者中,有13例(81.3%)排便频率增加。在使用聚葡萄糖30天后,23例患者中有20例(86.7%)发现聚葡萄糖的效果为:(1)便秘改善,(2)排便频率增加,(3)大便粘稠度软化,(4)其他肠道症状改善,或(5)泻药剂量减少,或以上两种。这些结果表明,聚葡萄糖治疗大肠黑素病患者习惯性便秘的临床效果。
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引用次数: 2
Replicability of the effect of Galactosylsucrose-containing food for specified health uses on fecal improvement in the case of availableness on usual life 特定保健用途含半乳糖糖的食品在可获得的情况下对日常生活的粪便改善效果的可复制性
Pub Date : 2002-12-31 DOI: 10.11217/JJDF1997.6.73
Sadako Nakamura, T. Oku
Food for specified health uses is permitted one by one, and the specific health effect has to be certainly based on the scientific evidences. These evidences must be based on the results from the experimental protocol and be gotten under several experimental regulations. It has not been clarified whether the result of specific health effects are replicated and applicable or not, in the case of availableness on usual life. Oligosaccharides and sugar alcohols have the beneficial health effects and are often used for the ingredients of the food for specified health uses. The aim of this study is to estimate the replicability of the effect on the improvement of fecal conditions, when galactosylsucrose-containing food for specified health uses is ingested on the usual life. The subjects of this study (51 females, age; 20.1•}2.1y.) have to ingest one package (48g, 12g•~4 pieces) of the cookies type of food for specified health uses containing 4g of
特定保健用途的食品是一种一种允许的,具体的保健效果必须有科学依据。这些证据必须以实验方案的结果为基础,并在若干实验规则下得到。目前还不清楚具体健康影响的结果是否可复制,是否适用于日常生活。低聚糖和糖醇具有有益健康的作用,通常用于特定保健用途的食品成分。本研究的目的是估计在日常生活中摄入用于特定保健用途的含半乳糖糖的食物对改善粪便状况的影响的可复制性。本研究对象(女性51名,年龄;20.1••2.1y.)必须摄入一包(48克,12克••4片)含有4克叶酸的特定健康用途饼干类食品
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引用次数: 9
Effects of intestinal microflora on host immune mechanism 肠道菌群对宿主免疫机制的影响
Pub Date : 2002-12-31 DOI: 10.11217/JJDF1997.6.41
H. Yasui
Lactic acid bacteria (LAB) in intestinal flora are useful in maintaining good health. Recently, it has been reported that LAB act on the immune mechanism and increase the body's resistance to infection, cancer and allergy. In this paper, it was showed that oral administration of Bifidobacterium breve YIT4064 (B. breve) to mice activated the humoral immune system, augmented anti-rotavirus IgA production or anti-influenza virus (IFV) IgG production and protected against rotavirus infection or influenza infection, respectively. Furthermore, when the B. breve was given to infants, there was a significant reduction of the frequency of rotavirus shedding in stool samples during the administration of the bacteria. It was also found, again using mice, that oral administration of Lactobacillus casei strain Shirota (LcS) stimulated type 1 helper T (Th1) cells, activated the cellular immune system, inhibited incidences of tumors, influenza infection and IgE production. In the human study, it was demonstrated that oral administration of LcS into surgical operated patients suppressed the recurrence of superficial bladder cancer in a double-blind clinical trial. On the basis of both our data and the data of other authors, it was showed that some strains of Bi adobacterium and Lactobacillus had immunomodulatory activities and were able to protect against various diseases .
肠道菌群中的乳酸菌对维持身体健康有重要作用。近年来,有报道称乳酸菌可作用于免疫机制,增强机体对感染、癌症和过敏的抵抗力。本研究表明,小鼠口服短双歧杆菌YIT4064 (B. breve)可激活体液免疫系统,增加抗轮状病毒IgA和抗流感病毒IgG的产生,并对轮状病毒感染和流感感染具有保护作用。此外,当给予婴儿短芽胞杆菌时,在给予细菌期间,粪便样本中轮状病毒脱落的频率显着减少。同样在小鼠实验中,研究人员还发现,口服干酪乳杆菌Shirota (LcS)可以刺激1型辅助性T细胞(Th1),激活细胞免疫系统,抑制肿瘤的发生、流感感染和IgE的产生。在人体研究中,一项双盲临床试验表明,手术患者口服LcS可抑制浅表性膀胱癌的复发。根据我们的数据和其他作者的数据,表明一些adobacterium和Lactobacillus菌株具有免疫调节活性,能够预防各种疾病。
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引用次数: 0
Estimation of available energy of dietary fiber in various food materials 各种食品原料中膳食纤维有效能的估算
Pub Date : 2002-12-31 DOI: 10.11217/JJDF1997.6.81
T. Oku, Kazuhiko Yamada, Ken-ichi Kanaya
加工食品には栄養成分表示制度に基づいてエ ネルギ ーをはじめ主要栄養成分表示 が義務付 けられてい る。 食物繊維含有加工食品において も例外ではない。栄養 改善法(現 ・健康増進法)に おける加工食品の栄養表 示 制度 で は,食 物 繊維 の エ ネル ギ ー値 は暫 定的 に 4kcal/9を 用いている。 このため,加 工食品のエ ネル ギー量 が多 くな り,特 別用途食品に位置づけ られてい る低カロリー食品などの創製が困難 になっている。一 方,欧 米諸国では,食 物繊維のエネルギー値 は暫定的 にOkca1/gを 用いてきたが,最 近では真実に近い評価 をす る動 きがでて きて,国 によってOkcal/gあ るいは 2kca1/gを 使 っている。 当初,わ が国の栄養成分表示制度 におけるエネルギ ーにつ いては ,炭 水化物 から食物繊維や難消化性 オ リ ゴ糖 ・糖アルコール除いた量 に4kca1/gを 乗 じ,食 物 繊維はOkca1/g,難 消化性オ リゴ糖や糖アルコールは それぞれのエネルギー換算係数 を乗 じ,こ れ らの和 を 炭水化物のエネルギー量 としていた。そ して,食 物繊 維 や難消化性オ リゴ糖 ・糖アル コール含量が少な く, 総エ ネルギー量への影響 が少 ない加工食品について は,炭 水化物へ直接4kcal/gを 乗 じてエネルギー量 と して もよいと していた。ところが,日 本食品標準成分 表の改訂が行われた ときに,食 物繊維のエネルギーを 暫定的に4kca1/gと して取 り扱 うこととしために,食 品業界に混乱 をもた らしている。 いずれに しても,こ のような混乱 が生 じているのは 食物繊維のエネルギー量 が明 らかに されていないか ら である。それゆえ,現 段階における科学的根拠 に基づ いて,各 々の食物繊維素材についてエネルギー評価 を 行い,よ り真実 に近いエネル ギー値 を提示す る必要が ある。 ここでは,先 ず現段階 における知見 に基づ く食 物繊維エネルギー評価の進め方 を提示 し,次 にこの考 え方にもとついて,現 在,わ が国において商品化 され てい る食物繊維素材につ いてエネル ギー評価 を試み, エネルギー換算係数を提示す る。
在加工食品中,根据营养成分标示制度,义务标明包括茴香在内的主要营养成分。含有食物纤维的加工食品也不例外。在营养改善法(现健康增进法)的加工食品营养表制度中,膳食纤维的hennelgi值暂时采用4kcal/9。因此,加工食品的超量过多,难以生产定位于特殊用途食品的低热量食品。另一方面,在欧洲和美国国家,食物纤维的能量值暂时使用Okca1/g,但最近出现了接近真实的评价的动向,各个国家的Okcal/g相似度使用2kca1/g。当初,我国的营养成分标示制度中关于能源的规定是:炭水化物中除去食物纤维、难消化性聚糖、糖醇后的量乘4kca1/g。纤维为Okca1/g,难消化性聚糖和糖醇乘除各自的能量换算系数,两者之和即为碳水化合物的能量量。而且,食物纤维和难消化性聚糖、糖醇含量少,对于对总能源量影响较小的加工食品,可以直接在碳水化物上乘以4kcal/g作为能源量。但是,在修订日本食品标准成分表时,将食品纤维的能量暂定为4kca1/g,因此在食品业界引起了混乱。不管怎样,产生这种混乱的原因是没有明确膳食纤维的能量量。因此,基于现阶段的科学依据,有必要对各种膳食纤维材料进行能量评估,提出更接近真实的enelgy值。在这里,首先提出了基于现阶段的知识的食物纤维能量评价的推进方法,接着结合这个思考方法,对目前在我国商品化的食物纤维材料进行探讨。尝试基质评价,提出能量换算系数。
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引用次数: 8
期刊
Journal of Japanese Association for Dietary Fiber Research
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