{"title":"SLC2A9（GLUT9）遺伝子多型とレニン−アンジオテンシン系活性化に関するメンデルランダム化法による関連解析","authors":"T. Konoshita, M. Urabe, Y. Makino","doi":"10.6032/GNAM.42.73","DOIUrl":"https://doi.org/10.6032/GNAM.42.73","url":null,"abstract":"","PeriodicalId":12746,"journal":{"name":"GOUT AND NUCLEIC ACID METABOLISM","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81417937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"新規尿酸排泄促進剤FYU-981の健常人男性におけるPK/PDモデリング解析","authors":"K. Sekine, M. Fushimi, I. Tamai","doi":"10.6032/gnam.42.111","DOIUrl":"https://doi.org/10.6032/gnam.42.111","url":null,"abstract":"","PeriodicalId":12746,"journal":{"name":"GOUT AND NUCLEIC ACID METABOLISM","volume":"140 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77734998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Takayanagi, Yohei Nonaka, T. Fukuuchi, N. Yamaoka, M. Yasuda, K. Mawatari, Kazuya Nakagomi, K. Kaneko
{"title":"糠漬け，塩糀漬け発酵による食品中プリン体の変化","authors":"F. Takayanagi, Yohei Nonaka, T. Fukuuchi, N. Yamaoka, M. Yasuda, K. Mawatari, Kazuya Nakagomi, K. Kaneko","doi":"10.6032/gnam.42.93","DOIUrl":"https://doi.org/10.6032/gnam.42.93","url":null,"abstract":"","PeriodicalId":12746,"journal":{"name":"GOUT AND NUCLEIC ACID METABOLISM","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74040285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Machi Tanaka, Hiroshi Ooyama, Mieko Yokozeki, Mika Ootsuki, H. Moromizato, K. Ooyama, Shin Fujimori
{"title":"肥満高尿酸血症・痛風患者への栄養指導（旧題：BMI25以上の痛風患者への栄養指導）","authors":"Machi Tanaka, Hiroshi Ooyama, Mieko Yokozeki, Mika Ootsuki, H. Moromizato, K. Ooyama, Shin Fujimori","doi":"10.6032/gnam.42.67","DOIUrl":"https://doi.org/10.6032/gnam.42.67","url":null,"abstract":"","PeriodicalId":12746,"journal":{"name":"GOUT AND NUCLEIC ACID METABOLISM","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75810420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Asuka Morita, M. Ouchi, Yusuke Otsuka, N. Otani, Promsuk Jutabha, T. Fujita, N. Anzai
{"title":"腎尿酸排泄低下型モデルマウスでのジヒドロピリジン系カルシウム拮抗薬による尿酸排泄効果の検討","authors":"Asuka Morita, M. Ouchi, Yusuke Otsuka, N. Otani, Promsuk Jutabha, T. Fujita, N. Anzai","doi":"10.6032/gnam.42.80","DOIUrl":"https://doi.org/10.6032/gnam.42.80","url":null,"abstract":"","PeriodicalId":12746,"journal":{"name":"GOUT AND NUCLEIC ACID METABOLISM","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78706092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yuki Fujimura, Shu-ichi Fujita, Y. Kanzaki, T. Murase, Takashi Nakamura, K. Sohmiya, N. Ishizaka
Results Among 165 patients(55women)enrolled, 25 patients(15%)were diagnosed to have diastolic dysfunction. Although diastolic dysfunction tended to be more prevalent among those with lower XOR activity tertiles (P= 0.071), logistic regression analysis showed that the highest UA tertile, but not the lowest XOR activity tertile, was associated with diastolic dysfunction after adjustment for age, gender, log (eGFR), and uric acid, although the highest UA tertile was significantly associated with diastolic dysfunction. When analysis was performed in an each genderseparated manner plasma XOR activity was not significantly associated with diastolic dysfunction.
{"title":"Are patients with higher plasma xanthine oxidase activity more likely to have cardiac diastolic dysfunction.","authors":"Yuki Fujimura, Shu-ichi Fujita, Y. Kanzaki, T. Murase, Takashi Nakamura, K. Sohmiya, N. Ishizaka","doi":"10.6032/gnam.42.138","DOIUrl":"https://doi.org/10.6032/gnam.42.138","url":null,"abstract":"Results Among 165 patients(55women)enrolled, 25 patients(15%)were diagnosed to have diastolic dysfunction. Although diastolic dysfunction tended to be more prevalent among those with lower XOR activity tertiles (P= 0.071), logistic regression analysis showed that the highest UA tertile, but not the lowest XOR activity tertile, was associated with diastolic dysfunction after adjustment for age, gender, log (eGFR), and uric acid, although the highest UA tertile was significantly associated with diastolic dysfunction. When analysis was performed in an each genderseparated manner plasma XOR activity was not significantly associated with diastolic dysfunction.","PeriodicalId":12746,"journal":{"name":"GOUT AND NUCLEIC ACID METABOLISM","volume":"65 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78743981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Practice Guideline for Renal Hypouricemia","authors":"","doi":"10.6032/gnam.42.suppl-1","DOIUrl":"https://doi.org/10.6032/gnam.42.suppl-1","url":null,"abstract":"","PeriodicalId":12746,"journal":{"name":"GOUT AND NUCLEIC ACID METABOLISM","volume":"158 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74297170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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