Pub Date : 2024-07-30DOI: 10.30574/gscarr.2024.20.1.0271
Kerem Kemal Soylemez, Joanne Lusher, Marina Rachitskiy
Some behaviours and individual characteristics can be labelled as offensive. In today’s world, almost any behaviour or characteristic might be perceived as deviating from the norm by any specific observer. Naturism, which has recently gained the interest of scholars, refers to engaging in nudity without the intention of any sexual stimulation. There is vast literature which explores perceptions and beliefs towards individuals who belong to minority groups. However, there is a current gap in the literature when it comes to understanding perceptions of textiles (non-naturists) towards naturism. The present qualitative study addresses this gap by representing non-naturists’ voices surrounding their beliefs towards naturism. Ten participants were recruited to collect rich and detailed data by convenience sampling method to explore their beliefs and perceptions towards naturism. Two distinct themes emerged from a reflective thematic analysis of the dataset: Incognizant acceptance and Beliefs surrounding naturists. Participant narratives suggest that individuals who are non-naturists but unfamiliar with naturism have a limited understanding of what it is. The findings of the present study assist in deepening our understanding of naturism and offer to challenge societal beliefs and values in relation to naturism.
{"title":"Exposing perceptions and beliefs towards naturism: A qualitative exploration of personal narratives","authors":"Kerem Kemal Soylemez, Joanne Lusher, Marina Rachitskiy","doi":"10.30574/gscarr.2024.20.1.0271","DOIUrl":"https://doi.org/10.30574/gscarr.2024.20.1.0271","url":null,"abstract":"Some behaviours and individual characteristics can be labelled as offensive. In today’s world, almost any behaviour or characteristic might be perceived as deviating from the norm by any specific observer. Naturism, which has recently gained the interest of scholars, refers to engaging in nudity without the intention of any sexual stimulation. There is vast literature which explores perceptions and beliefs towards individuals who belong to minority groups. However, there is a current gap in the literature when it comes to understanding perceptions of textiles (non-naturists) towards naturism. The present qualitative study addresses this gap by representing non-naturists’ voices surrounding their beliefs towards naturism. Ten participants were recruited to collect rich and detailed data by convenience sampling method to explore their beliefs and perceptions towards naturism. Two distinct themes emerged from a reflective thematic analysis of the dataset: Incognizant acceptance and Beliefs surrounding naturists. Participant narratives suggest that individuals who are non-naturists but unfamiliar with naturism have a limited understanding of what it is. The findings of the present study assist in deepening our understanding of naturism and offer to challenge societal beliefs and values in relation to naturism.","PeriodicalId":12791,"journal":{"name":"GSC Advanced Research and Reviews","volume":"3 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141796102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The financial technology (fintech) sector has witnessed remarkable expansion in recent years, fundamentally reshaping the landscape of financial services delivery and consumption. This growth is driven by new technologies such as mobile banking, digital wallets, blockchain and artificial intelligence Keenan the risk for fintech has increased. As pioneers in the use of technology to enhance financial transactions, Fintech has become an attractive target for cybercriminals looking to exploit weaknesses in digital infrastructure. The evolving nature and sophistication of cyber threats, including phishing attacks, ransomware, data breaches, and insider threats, pose significant risks to the integrity and security of financial data and assets. This paper aims to provide a comprehensive review of cybersecurity strategies implemented within the fintech industry to safeguard against these threats. It examines the current landscape of cyber risks facing fintech firms, highlighting the multifaceted challenges posed by malicious actors and technological vulnerabilities. Moreover, the paper evaluates the effectiveness of various cybersecurity measures adopted by fintech companies, such as encryption protocols, multi-factor authentication, AI-driven threat detection, and blockchain technology. Furthermore, the review discusses emerging trends and technologies poised to bolster cybersecurity in the fintech sector. These include advancements in quantum-resistant encryption, zero-trust architecture, regulatory compliance frameworks (e.g., GDPR, PCI DSS), and proactive incident response strategies. By exploring these innovative approaches, the paper seeks to illuminate proactive measures that can mitigate cyber risks and enhance resilience in fintech operations.
{"title":"Cybersecurity strategies in fintech: safeguarding financial data and assets","authors":"Omolara Patricia Olaiya, Temitayo Oluwadamilola Adesoga, Adefisayo Ojo, Oluwabusola Dorcas Olagunju, Olajumoke Oluwagbemisola Ajayi, Yusuf Olalekan Adebayo","doi":"10.30574/gscarr.2024.20.1.0241","DOIUrl":"https://doi.org/10.30574/gscarr.2024.20.1.0241","url":null,"abstract":"The financial technology (fintech) sector has witnessed remarkable expansion in recent years, fundamentally reshaping the landscape of financial services delivery and consumption. This growth is driven by new technologies such as mobile banking, digital wallets, blockchain and artificial intelligence Keenan the risk for fintech has increased. As pioneers in the use of technology to enhance financial transactions, Fintech has become an attractive target for cybercriminals looking to exploit weaknesses in digital infrastructure. The evolving nature and sophistication of cyber threats, including phishing attacks, ransomware, data breaches, and insider threats, pose significant risks to the integrity and security of financial data and assets. This paper aims to provide a comprehensive review of cybersecurity strategies implemented within the fintech industry to safeguard against these threats. It examines the current landscape of cyber risks facing fintech firms, highlighting the multifaceted challenges posed by malicious actors and technological vulnerabilities. Moreover, the paper evaluates the effectiveness of various cybersecurity measures adopted by fintech companies, such as encryption protocols, multi-factor authentication, AI-driven threat detection, and blockchain technology. Furthermore, the review discusses emerging trends and technologies poised to bolster cybersecurity in the fintech sector. These include advancements in quantum-resistant encryption, zero-trust architecture, regulatory compliance frameworks (e.g., GDPR, PCI DSS), and proactive incident response strategies. By exploring these innovative approaches, the paper seeks to illuminate proactive measures that can mitigate cyber risks and enhance resilience in fintech operations.","PeriodicalId":12791,"journal":{"name":"GSC Advanced Research and Reviews","volume":"10 14","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141796274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-30DOI: 10.30574/gscarr.2024.20.1.0242
Anthoula-Ioanna Kritikou, Myrto-Evangelia Nikolaidi, Thomas Chavianidis
The purpose of this paper is to investigate the role of mobile health applications as tools for managing or coping with stress. The research was conducted by searching a variety of databases, including Google Scholar, ResearchGate, and JMIR Mhealth Uhealth Publications.
本文旨在研究移动医疗应用程序作为管理或应对压力的工具所发挥的作用。研究是通过搜索各种数据库进行的，包括 Google Scholar、ResearchGate 和 JMIR Mhealth Uhealth Publications。
{"title":"The role of mobile applications in managing everyday stress through breathing","authors":"Anthoula-Ioanna Kritikou, Myrto-Evangelia Nikolaidi, Thomas Chavianidis","doi":"10.30574/gscarr.2024.20.1.0242","DOIUrl":"https://doi.org/10.30574/gscarr.2024.20.1.0242","url":null,"abstract":"The purpose of this paper is to investigate the role of mobile health applications as tools for managing or coping with stress. The research was conducted by searching a variety of databases, including Google Scholar, ResearchGate, and JMIR Mhealth Uhealth Publications.","PeriodicalId":12791,"journal":{"name":"GSC Advanced Research and Reviews","volume":"3 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141795862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-30DOI: 10.30574/gscarr.2024.20.1.0239
Sharique Ahmad, Raushan Kumar, V. Rashi, Geetika Kapoor, Priyesh Srivastava, Mohd. Ibrahim
Keeping cells in a state of balance and optimal function requires proper cellular waste management. Autophagy and the (ubiquitin-proteasome system) UPS, two well-established routes, have been the subject of substantial research. A growing body of evidence suggests that alternate cellular disposal pathways may play a role in several health problems. This review delves into the inner workings of these alternate routes and how they relate to health and illness. Microautophagy, chaperone-mediated autophagy (CMA), and production of extracellular vesicles (EVs) are our main areas of interest. Our discussion centres on their role in neurodegenerative illnesses, cancer, and metabolic disorders, with an emphasis on possible treatments for these conditions. Novel insights into disease causes and possible treatments can be gained by understanding these pathways. Microautophagy entails direct lysosomal engulfment of cellular material, CMA selectively targets cytosolic proteins for lysosomal degradation, while EV secretion controls waste by exporting it out of the cell. Dysfunction in these pathways can result in pathological diseases, as they are essential for cellular integrity maintenance. This study highlights the significance of potential alternative disposal systems in cellular health and disease management by outlining their functions in different diseases and investigating new treatments that aim to block these pathways.
要使细胞保持平衡和最佳功能状态，就必须妥善管理细胞废物。自噬和（泛素-蛋白酶体系统）UPS 这两种成熟的途径一直是大量研究的主题。越来越多的证据表明，另一种细胞废物处理途径可能在多种健康问题中发挥作用。本综述将深入探讨这些交替途径的内部运作，以及它们与健康和疾病的关系。微自噬、伴侣介导的自噬（CMA）和细胞外囊泡（EVs）的产生是我们关注的主要领域。我们的讨论集中于它们在神经退行性疾病、癌症和代谢紊乱中的作用，重点是这些疾病的可能治疗方法。通过了解这些途径，我们可以对疾病的原因和可能的治疗方法有新的认识。微自噬需要溶酶体直接吞噬细胞物质，CMA 选择性地将细胞膜蛋白作为溶酶体降解的目标，而 EV 分泌则通过将废物排出细胞来控制废物。这些途径的功能障碍会导致病理疾病，因为它们对维持细胞完整性至关重要。本研究概述了潜在的替代处置系统在不同疾病中的功能，并研究了旨在阻断这些途径的新疗法，从而强调了这些系统在细胞健康和疾病管理中的重要意义。
{"title":"Alternative cellular disposal pathway-related health issues: A review","authors":"Sharique Ahmad, Raushan Kumar, V. Rashi, Geetika Kapoor, Priyesh Srivastava, Mohd. Ibrahim","doi":"10.30574/gscarr.2024.20.1.0239","DOIUrl":"https://doi.org/10.30574/gscarr.2024.20.1.0239","url":null,"abstract":"Keeping cells in a state of balance and optimal function requires proper cellular waste management. Autophagy and the (ubiquitin-proteasome system) UPS, two well-established routes, have been the subject of substantial research. A growing body of evidence suggests that alternate cellular disposal pathways may play a role in several health problems. This review delves into the inner workings of these alternate routes and how they relate to health and illness. Microautophagy, chaperone-mediated autophagy (CMA), and production of extracellular vesicles (EVs) are our main areas of interest. Our discussion centres on their role in neurodegenerative illnesses, cancer, and metabolic disorders, with an emphasis on possible treatments for these conditions. Novel insights into disease causes and possible treatments can be gained by understanding these pathways. Microautophagy entails direct lysosomal engulfment of cellular material, CMA selectively targets cytosolic proteins for lysosomal degradation, while EV secretion controls waste by exporting it out of the cell. Dysfunction in these pathways can result in pathological diseases, as they are essential for cellular integrity maintenance. This study highlights the significance of potential alternative disposal systems in cellular health and disease management by outlining their functions in different diseases and investigating new treatments that aim to block these pathways.","PeriodicalId":12791,"journal":{"name":"GSC Advanced Research and Reviews","volume":"13 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141795902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study aims to · Examine the satisfaction associated with hybrid work models, · Investigate perceptions of hybrid work models, and · Explore the relationship between demographic factors, perception factors, and satisfaction with hybrid work models. This research is quantitative in nature, utilizing questionnaires for data collection. The sample group consists of 190 supporting staff from the Electricity Generating Authority of Thailand in the Southern region. Statistical analyses employed include percentage values, arithmetic mean, standard deviation, and Pearson correlation analysis. The findings reveal that · In terms of satisfaction with the hybrid work model, most employees are primarily satisfied with their well-being and the amount of time spent working, followed by job achievement, work-life balance, and cost savings, respectively. · Regarding perceptions, most employees perceive the greatest benefits, followed by ease of use, supportive resources and technology, and commuting between home and work. · Different demographic factors do not impact satisfaction with the hybrid work model, and overall, perception factors are significantly statistically correlated with satisfaction with the hybrid work model at the 0.05 level.
{"title":"Satisfactions regarding the hybrid working model of the supporting staff of the electricity generating authority of Thailand in the southern region","authors":"Nattaachai Meesith, Nattachai Meesith, Somnuk Aujirapongpan","doi":"10.30574/gscarr.2024.18.3.0099","DOIUrl":"https://doi.org/10.30574/gscarr.2024.18.3.0099","url":null,"abstract":"This study aims to · Examine the satisfaction associated with hybrid work models, · Investigate perceptions of hybrid work models, and · Explore the relationship between demographic factors, perception factors, and satisfaction with hybrid work models. This research is quantitative in nature, utilizing questionnaires for data collection. The sample group consists of 190 supporting staff from the Electricity Generating Authority of Thailand in the Southern region. Statistical analyses employed include percentage values, arithmetic mean, standard deviation, and Pearson correlation analysis. The findings reveal that · In terms of satisfaction with the hybrid work model, most employees are primarily satisfied with their well-being and the amount of time spent working, followed by job achievement, work-life balance, and cost savings, respectively. · Regarding perceptions, most employees perceive the greatest benefits, followed by ease of use, supportive resources and technology, and commuting between home and work. · Different demographic factors do not impact satisfaction with the hybrid work model, and overall, perception factors are significantly statistically correlated with satisfaction with the hybrid work model at the 0.05 level.","PeriodicalId":12791,"journal":{"name":"GSC Advanced Research and Reviews","volume":"58 39","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140362463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-30DOI: 10.30574/gscarr.2024.18.3.0115
Kefas Osayi Eko, Yakubu Boyi Ngwai, David Ishaleku, Isaac Iyiayem Igbawua
The most common bacteria associated with urinary tract infections (UTIs) worldwide Escherichia coli. To treat UTIs, Fluoroquinolones are widely used especially Ciprofloxacin. The honey moon did not last long due to the development of resistance acquired by the bacteria as a result of resistance gene. This study investigated ciprofloxacin resistant urinary E. coli resistance via plasmid-mediated quinolone resistance (PMQR) genes rather than the chromosomal mutation of patients attending some Healthcentres in Nasarawa-West Senatorial District, Nasarawa State, Nigeria. Ninety-Two (92) 42% confirmed ciprofloxacin urinary resistant E. coli from patients attending the three (3) study Centres were screened for the presence of PMQR resistant genes (aac(6’)-Ib-cr, oqxA, oqxB, qnrA, qnrB, qnrS) using polymerase chain reaction (PCR) method. The screening detected the presence of QnrA 4(44.4%), QnrB and QnrS both with 5(55.6%) occurrence, meaning aac(6’)-Ib-cr, QnrVC ,GyrA, ParC and others were not detected. It is clear that these isolates harbored some PMQR genes both singly and in combination. This is a strong warning to both the prescribers and users of Antibiotic of the consequences of negligence of strict adherence to the usage of antimicrobials, since resistance to antibiotics has led to death of great number of People worldwide.
{"title":"Molecular Characterization of Plasmid-Mediated Quinolone resistance in Urinary Escherichia coli from some Healthcentres in Nasarawa-West Senatorial District, Nasarawa State, Nigeria","authors":"Kefas Osayi Eko, Yakubu Boyi Ngwai, David Ishaleku, Isaac Iyiayem Igbawua","doi":"10.30574/gscarr.2024.18.3.0115","DOIUrl":"https://doi.org/10.30574/gscarr.2024.18.3.0115","url":null,"abstract":"The most common bacteria associated with urinary tract infections (UTIs) worldwide Escherichia coli. To treat UTIs, Fluoroquinolones are widely used especially Ciprofloxacin. The honey moon did not last long due to the development of resistance acquired by the bacteria as a result of resistance gene. This study investigated ciprofloxacin resistant urinary E. coli resistance via plasmid-mediated quinolone resistance (PMQR) genes rather than the chromosomal mutation of patients attending some Healthcentres in Nasarawa-West Senatorial District, Nasarawa State, Nigeria. Ninety-Two (92) 42% confirmed ciprofloxacin urinary resistant E. coli from patients attending the three (3) study Centres were screened for the presence of PMQR resistant genes (aac(6’)-Ib-cr, oqxA, oqxB, qnrA, qnrB, qnrS) using polymerase chain reaction (PCR) method. The screening detected the presence of QnrA 4(44.4%), QnrB and QnrS both with 5(55.6%) occurrence, meaning aac(6’)-Ib-cr, QnrVC ,GyrA, ParC and others were not detected. It is clear that these isolates harbored some PMQR genes both singly and in combination. This is a strong warning to both the prescribers and users of Antibiotic of the consequences of negligence of strict adherence to the usage of antimicrobials, since resistance to antibiotics has led to death of great number of People worldwide.","PeriodicalId":12791,"journal":{"name":"GSC Advanced Research and Reviews","volume":"54 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140363031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The purpose of this research is to study the education of gifted students in Greece and in various European countries and the role of Information and Communication Technologies (ICT) in the education of gifted students. This study is a literature review and for the writing of which were used articles from various platforms (Research Gate, google scholar etc.). The first part distinguishes giftedness from talent and also refers to the strategies to support gifted students (differentiated instruction, enrichment, grouping and concentration). While, the second part analyses the way of education of gifted students in Greece and in different European countries (e.g. Netherlands, Switzerland, Czech Republic, Slovakia etc.). Finally, the role of ICT in the education of gifted students is discussed.
{"title":"The education of gifted students in Greece and Europe and the use of ICT","authors":"Despina Dimitriadou, Neslisah Emin, Parthena-Marina Kiremitsidou, Stavroula Mpouzelou","doi":"10.30574/gscarr.2024.18.3.0086","DOIUrl":"https://doi.org/10.30574/gscarr.2024.18.3.0086","url":null,"abstract":"The purpose of this research is to study the education of gifted students in Greece and in various European countries and the role of Information and Communication Technologies (ICT) in the education of gifted students. This study is a literature review and for the writing of which were used articles from various platforms (Research Gate, google scholar etc.). The first part distinguishes giftedness from talent and also refers to the strategies to support gifted students (differentiated instruction, enrichment, grouping and concentration). While, the second part analyses the way of education of gifted students in Greece and in different European countries (e.g. Netherlands, Switzerland, Czech Republic, Slovakia etc.). Finally, the role of ICT in the education of gifted students is discussed.","PeriodicalId":12791,"journal":{"name":"GSC Advanced Research and Reviews","volume":"56 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140363167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-30DOI: 10.30574/gscarr.2024.18.3.0113
Juan Carlos Prieto, Viviana Noriega, Hugo F. Miranda
Statins are widely used in cardiovascular disease as cholesterol lowering drugs. However, they also have other actions (pleiotropic effects) including antiproliferative, antithrombotic, neuroprotective, immunomodulatory, anti-inflammatory and antinociceptive activity. The aim of this study was to determine the antinociception properties of rosuvastatin in two murine models of pain and the involvement of opioid antagonists (naltrexone, naltrindole, norbinaltorphimine), risperidone, and L-NAME (L-NG-nitro arginine methyl ester) in this effect. Rosuvastatin was chosen among available statins because it is commonly prescribed and has high potency, efficacy, and an acceptable safety profile. Rosuvastatin antinociception was evaluated in the acetic acid writhing test and the formalin hind paw test by dose-response curves, before and after the i.p. administration of opioid antagonists, risperidone, and L-NAME. This work demonstrates that the assayed drugs modulate the antinociceptive effect of rosuvastatin in both experimental murine pain tests. The antinociception effect described for rosuvastatin may be due to a particular modulation induced by the opioid antagonists, risperidone and L-NAME. Given the broad effects of rosuvastatin, the results of this study may have novel clinical implications in the therapy of pain.
{"title":"Antinociception induced by rosuvastatin in mice: Modulation by opioid receptor antagonists, risperidone and l-name","authors":"Juan Carlos Prieto, Viviana Noriega, Hugo F. Miranda","doi":"10.30574/gscarr.2024.18.3.0113","DOIUrl":"https://doi.org/10.30574/gscarr.2024.18.3.0113","url":null,"abstract":"Statins are widely used in cardiovascular disease as cholesterol lowering drugs. However, they also have other actions (pleiotropic effects) including antiproliferative, antithrombotic, neuroprotective, immunomodulatory, anti-inflammatory and antinociceptive activity. The aim of this study was to determine the antinociception properties of rosuvastatin in two murine models of pain and the involvement of opioid antagonists (naltrexone, naltrindole, norbinaltorphimine), risperidone, and L-NAME (L-NG-nitro arginine methyl ester) in this effect. Rosuvastatin was chosen among available statins because it is commonly prescribed and has high potency, efficacy, and an acceptable safety profile. Rosuvastatin antinociception was evaluated in the acetic acid writhing test and the formalin hind paw test by dose-response curves, before and after the i.p. administration of opioid antagonists, risperidone, and L-NAME. This work demonstrates that the assayed drugs modulate the antinociceptive effect of rosuvastatin in both experimental murine pain tests. The antinociception effect described for rosuvastatin may be due to a particular modulation induced by the opioid antagonists, risperidone and L-NAME. Given the broad effects of rosuvastatin, the results of this study may have novel clinical implications in the therapy of pain.","PeriodicalId":12791,"journal":{"name":"GSC Advanced Research and Reviews","volume":"47 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140363299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-30DOI: 10.30574/gscarr.2024.18.3.0114
Wisdom Samuel, Wisdom Samuel Udo, Nneka Adaobi Ochuba, Olatunji Akinrinola, Yinka James Ololade
This review paper presents a comparative analysis of theoretical approaches to data analytics and decision-making in the finance sectors of Africa and the United States. It explores how these approaches are adopted and implemented, considering each region's unique economic, technological, and regulatory environments. The paper identifies challenges and opportunities presented by these environments. It examines the influence of cultural and economic factors on the preference for certain theoretical models. It discusses practical implications for financial analysts, investors, and policymakers. It provides policy recommendations to foster an environment supportive of effective financial decision-making practices. The paper also speculates on the future of finance, suggesting areas for further research, including the empirical validation of theoretical approaches.
{"title":"Theoretical approaches to data analytics and decision-making in finance: Insights from Africa and the United States","authors":"Wisdom Samuel, Wisdom Samuel Udo, Nneka Adaobi Ochuba, Olatunji Akinrinola, Yinka James Ololade","doi":"10.30574/gscarr.2024.18.3.0114","DOIUrl":"https://doi.org/10.30574/gscarr.2024.18.3.0114","url":null,"abstract":"This review paper presents a comparative analysis of theoretical approaches to data analytics and decision-making in the finance sectors of Africa and the United States. It explores how these approaches are adopted and implemented, considering each region's unique economic, technological, and regulatory environments. The paper identifies challenges and opportunities presented by these environments. It examines the influence of cultural and economic factors on the preference for certain theoretical models. It discusses practical implications for financial analysts, investors, and policymakers. It provides policy recommendations to foster an environment supportive of effective financial decision-making practices. The paper also speculates on the future of finance, suggesting areas for further research, including the empirical validation of theoretical approaches.","PeriodicalId":12791,"journal":{"name":"GSC Advanced Research and Reviews","volume":"52 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140363608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-30DOI: 10.30574/gscarr.2024.18.3.0080
Rakshitha D, Jagadeesh G Mitti
Pharmacovigilance concerned with identifying the hazards associated with pharmaceutical products and with minimizing the risk of any harm that may come to patients and is defined as the science relating to the collection, detection, understanding, assessment, monitoring and prevention of adverse effects with pharmaceutical products. Adverse drug reaction (ADR) comes under the umbrella of Pharmacovigilance defined as the response to a drug which is noxious, unintended and which occurs at doses normally used in man for prophylaxis, diagnosis or therapy of disease or for the modification of a physiological function. This includes a case presentation reported for ADR; a 49 year old female patient visited the JSS Ayurveda Hospital, Mysuru on August 2023 and diagnosed to have Sandhivata. She was treated with medications internally and Kottamchukkadi churna for external application as lepa. On application of Kottamchukkadi churna, appearance of reddish rashes and itching over applied area of ankle joints of both legs was noticed. As such not any conclusive reports on Kottamchukkadi churna of previous ADRs have been reported. Currently there is utmost importance for ADR in clinical practice concerned to the public health is of prime importance; so there is a need to educate all the Medical Professionals and encourage them to analyse and report any adverse drug reaction or adverse effects that occur in a patient. This shall only be a step towards global acceptance of Ayurvedic drugs hence proper documentation and further evaluation is a need of the hour.
{"title":"Overview of adverse drug reaction: A case report","authors":"Rakshitha D, Jagadeesh G Mitti","doi":"10.30574/gscarr.2024.18.3.0080","DOIUrl":"https://doi.org/10.30574/gscarr.2024.18.3.0080","url":null,"abstract":"Pharmacovigilance concerned with identifying the hazards associated with pharmaceutical products and with minimizing the risk of any harm that may come to patients and is defined as the science relating to the collection, detection, understanding, assessment, monitoring and prevention of adverse effects with pharmaceutical products. Adverse drug reaction (ADR) comes under the umbrella of Pharmacovigilance defined as the response to a drug which is noxious, unintended and which occurs at doses normally used in man for prophylaxis, diagnosis or therapy of disease or for the modification of a physiological function. This includes a case presentation reported for ADR; a 49 year old female patient visited the JSS Ayurveda Hospital, Mysuru on August 2023 and diagnosed to have Sandhivata. She was treated with medications internally and Kottamchukkadi churna for external application as lepa. On application of Kottamchukkadi churna, appearance of reddish rashes and itching over applied area of ankle joints of both legs was noticed. As such not any conclusive reports on Kottamchukkadi churna of previous ADRs have been reported. Currently there is utmost importance for ADR in clinical practice concerned to the public health is of prime importance; so there is a need to educate all the Medical Professionals and encourage them to analyse and report any adverse drug reaction or adverse effects that occur in a patient. This shall only be a step towards global acceptance of Ayurvedic drugs hence proper documentation and further evaluation is a need of the hour.","PeriodicalId":12791,"journal":{"name":"GSC Advanced Research and Reviews","volume":"39 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140364033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：