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Long-Term Nerve Conduction Changes after Successful Treatment of Poems Syndrome: Two Case Reports 成功治疗Poems综合征后的长期神经传导改变:两例报告
Pub Date : 2021-01-01 DOI: 10.36648/1791-809X.15.3.814
W. Homenda, Szymon Kukulski
The POEMS syndrome is a rare disorder manifesting with polyneuropathy and plasma cell dyscrasia accompanied by other multisystemic symptoms. Sensorimotor demyelinating, axonal and mixed types of polyneuropathy are the most disturbing problems of patients often leading to disability. Here we present two patients successfully treated with autologous hematopoietic stem cells transplantation. Symptoms of the POEMS syndrome entirely resolved after the treatment. Nerve conduction studies were used to follow-up patients in complete remission for few years to analyze dynamics of nerves regeneration. Despite patients clinical performance improvement, the recovery of nerve conduction was not complete. In both patients nerves of upper limbs function was restored to the greater extent than in lower limbs. Improvement or stabilization of impairment of sensory nerves conduction was followed by similar motor nerves conduction dynamic in a given limb. In addition, worsening of the electrophysiological features was observed, completing the picture of complex and subtle changes of conduction after the POEMS syndrome treatment.
POEMS综合征是一种罕见的疾病,表现为多神经病变和浆细胞病变,并伴有其他多系统症状。感觉运动脱髓鞘,轴突和混合型多神经病变是最令人困扰的问题,往往导致残疾的患者。在此,我们报告了两例自体造血干细胞移植成功治疗的患者。经治疗后POEMS综合征症状完全消失。神经传导研究用于对完全缓解的患者随访数年,以分析神经再生的动态。尽管患者的临床表现有所改善,但神经传导恢复不完全。两例患者上肢神经功能恢复程度均高于下肢。感觉神经传导损伤的改善或稳定之后,在给定的肢体中,类似的运动神经传导是动态的。此外,观察到电生理特征的恶化,完成了POEMS综合征治疗后复杂而微妙的传导变化。
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引用次数: 0
Awareness, Use, Care of Insecticide-treated Bed Nets among Pregnant Women in Buea (Buea) and Bonassama (Douala) 布埃亚(布埃亚)和博纳萨马(杜阿拉)孕妇对驱虫蚊帐的认识、使用和护理
Pub Date : 2021-01-01 DOI: 10.36648/1791-809X.15.2.810
H. Ngouakam, J. Fru-cho, B. Tientche
Background: Malaria in pregnancy (MiP) remains a major health problem in Cameroon, with an unacceptably high annual maternal mortality rate pegged at 782 maternal deaths per 100,000 live births. Despite the gains made through the free distribution of Long Lasting Insecticide Treated Nets (LLITNs) during the antenatal visit and the mass campaign, there is a paucity of data about how pregnant women effectively care for LLITNs. Methods: This was a hospital-based descriptive cross-sectional study conducted from June 2016 to September 2017 among consecutive consenting pregnant women attending antenatal clinics in Bonassama Health District (BHDa) and Buea Health Districts (BHD) located in Douala and Buea respectively using structured questionnaires. Results: Seventy-eight point two (78.2%) of participants never used LLITNs in BHD compared to 7.0 % in BHDa. A greater proportion of participants in both health districts declared having acquired LLITNs during antenatal visits 502 (65.2%) and LLITNs acquisition were facilitated mostly by health workers (77.92 %) in BHD and (53.5%) BHDa. In BHD, 125 (32.5%) never washed their ITNs and the reasons cited were the difficulties to mount when removes 72 (18.7%) in BHD and 47 (12.2%) in BHDa. The majority of pregnant women do self-repaired 383(99.5%) their LLITNs when their damaged than taking them to the tailor 138(17.9%). Conclusion: The high level of knowledge of LLITNs in protecting pregnant women against mosquito bites does not parallel the use of LLITNs in the study population. Forgetfulness and heat were the main reasons for not using the LLITNs in both Health Districts. Continuous health education and sensitization on the use of LLITNs as an effective preventive method for malaria during pregnancy should be accelerated especially during an antenatal visit.
背景:孕期疟疾仍然是喀麦隆的一个主要健康问题,每年孕产妇死亡率高得令人无法接受,每10万活产782例孕产妇死亡。尽管通过在产前检查和群众运动期间免费分发长效驱虫蚊帐取得了成果,但缺乏关于孕妇如何有效护理长效驱虫蚊帐的数据。方法:这是一项基于医院的描述性横断面研究,于2016年6月至2017年9月在分别位于杜阿拉和布埃亚的博纳萨马卫生区(BHDa)和布埃亚卫生区(BHD)的产前诊所连续接受同意的孕妇中进行。结果:78.2%的BHD患者从未使用过llitn,而BHD患者的这一比例为7.0%。两个保健区的参与者在产前检查期间宣布获得llitn的比例更高(65.2%),BHD和BHDa的卫生工作者(77.92%)促进了llitn的获得(53.5%)。在BHD患者中,125例(32.5%)从未清洗过itn,原因是BHD患者中有72例(18.7%)和BHDa患者中有47例(12.2%)难以清除itn。大多数孕妇在llitn损坏时自行修复(99.5%),而不是将其送到裁缝处(17.9%)。结论:在保护孕妇免受蚊虫叮咬方面,llitn的高知识水平与研究人群中llitn的使用并不平行。健忘和炎热是两个卫生区不使用llitn的主要原因。应继续进行保健教育,并使人们认识到将小剂量药物作为孕期疟疾的有效预防方法,特别是在产前检查期间。
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引用次数: 1
Outcomes of Surgical Patients Admitted to the Intensive Care Unit of Jimma University Medical Center 吉马岛大学医学中心重症监护室外科病人的预后分析
Pub Date : 2021-01-01 DOI: 10.36648/1791-809X.21.S3.009
Dabessa Mosissa, S. Alemu, M. Rad, E. Yesuf
Background: Intensive Care Unit is a part of a hospital where critically ill patients that required advanced airways, respiratory or homodynamic support are admitted. However, the patterns of admission and outcome of the critical surgical patients admitted to Intensive Care Unit of Jimma University Medical Center not well understood. Therefore, the aim of this study was to assesspatterns of admission and outcome of surgical patients admitted the intensive care unit of Jimma University Medical Center. Methodology: A cross-sectional retrospective study was conducted in Jimma University Medical Center. Records of surgical patients admitted to intensive care unit from Sept1, 2016-Sept1, 2017 were reviewed. Data abstracted from patient records include diagnosis at admission and outcome of admission. Descriptive statistic, such as frequencies, proportions and means were calculated. Possible association patients’ outcome and predictor variables were determined using Chi- Square Test. Result: Duringone year, 113 surgical patients admitted to intensive care unit of Jimma University Medical Center. Males accounted 61.1% of the admission. Commonest diagnosis at admission was isolated head trauma accounting 36 out of 113 admissions (31.9%). Overall ICU complication rate was 46.9 %. Overall ICU mortality rate was 39.8%. The highest mortality rate was recorded for head injury at 52.8% Conclusion: High complication rate and mortality rate is indicative of poor quality of care in the intensive care unit of Jimma University Medical Center. Head injury mortality rate is particularly higher and need preventive measures.
背景:重症监护室是医院收治需要先进气道、呼吸或动态支持的危重患者的一部分。然而,Jimma大学医学中心重症监护室收治的外科危重患者的入院模式和预后尚不清楚。因此,本研究的目的是评估Jimma大学医学中心重症监护室外科患者的入院方式和预后。方法:在吉马大学医学中心进行横断面回顾性研究。回顾2016年9月1日至2017年9月1日入住重症监护病房的外科患者记录。从患者记录中提取的数据包括入院时的诊断和入院结果。计算描述性统计量,如频率、比例和平均值。采用卡方检验确定可能的关联、患者预后和预测变量。结果:一年内,113例外科患者在吉马大学医学中心重症监护室住院。男生占录取率61.1%。入院时最常见的诊断是孤立性头部创伤,占113例入院患者中的36例(31.9%)。ICU总并发症发生率为46.9%。ICU总死亡率为39.8%。结论:Jimma University Medical Center重症监护病房的高并发症发生率和高死亡率表明重症监护病房的护理质量较差。头部受伤死亡率特别高,需要采取预防措施。
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引用次数: 4
Covid-19 Messages, Mental Health and Foreign Aid Covid-19信息、心理健康和外援
Pub Date : 2021-01-01 DOI: 10.36648/1791-809X.21.15.826
Victor Ijaja John Mosugu Tegan Zacchaeus
The dissemination of public information during pandemics leads to fear mongering and misinformation. In the context of health communication, this paper suggests that health communication ought to be as clear as possible and easily interpretable. This can be achieved by broadcasting public service announcements through radio, television, and billboard platforms in local dialects and official languages. Furthermore, clear and effective messaging would empower people with the necessary tools to prevent infectious diseases and take control of their well-being. Moreover, this paper also explores the mental health burden that people have during the pandemic and the role that foreign aid can play in alleviating human suffering. In Africa, very little is known or researched when it comes to mental health which becomes a great issue of concern during the COVID-19 pandemic. As people experience different forms of anxiety and depression resulting from fear, uncertainty, and loneliness, there are very limited resources for seeking help. When compared to the global rate, the number of Africans who receive care for their mental health is extremely low due to cultural norms and the limited number of mental health facilities and professionals. Nonetheless, the ability to achieve desirable health outcomes can significantly be boosted by foreign aid. Foreign aid has proven to be a tool for alleviating human suffering during pandemics. Most developing countries rely on foreign aid in the wake of a pandemic either through monetary (bilateral/multilateral) assistance or relief items. In addition to providing emergency relief measures in highly informal sectors, foreign aid can be used as a tool to channel liquidity to small and medium-sized enterprises (SMEs), households, and informal workers. This paper takes a systems approach in highlighting the ways in which some of the aforementioned factors can be efficiently leveraged to curb the rate of disease spread, which in turn alleviates the burden of human suffering.
在大流行病期间传播公共信息导致散播恐惧和错误信息。在健康传播的背景下,本文建议健康传播应尽可能清晰易懂。这可以通过广播、电视和广告牌平台以当地方言和官方语言播放公益广告来实现。此外,明确和有效的信息传递将使人们获得必要的工具,以预防传染病并控制自己的福祉。此外,本文还探讨了人们在大流行期间的心理健康负担以及外援在减轻人类痛苦方面可以发挥的作用。在非洲,人们对心理健康知之甚少,这在2019冠状病毒病大流行期间成为一个令人关注的重大问题。当人们因恐惧、不确定和孤独而经历不同形式的焦虑和抑郁时,寻求帮助的资源非常有限。与全球比率相比,由于文化规范以及精神卫生设施和专业人员数量有限,接受精神卫生护理的非洲人人数极低。尽管如此,外国援助可以大大提高实现理想健康结果的能力。事实证明,外援是减轻大流行病期间人类痛苦的一种工具。大多数发展中国家在大流行之后依靠外援,要么通过货币(双边/多边)援助,要么通过救济项目。除了在高度非正规的部门提供紧急救济措施外,外援还可以作为一种工具,将流动资金输送给中小企业、家庭和非正规工人。本文采用了一种系统方法,强调了可以有效利用上述一些因素来遏制疾病传播速度的方法,从而减轻了人类痛苦的负担。
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引用次数: 1
Investigating the Effect of Appropriate Personal Protective Equipment on the Stress Level of Care Workers in the Covid19 Epidemic 调查covid - 19疫情中适当的个人防护装备对护理人员压力水平的影响
Pub Date : 2021-01-01 DOI: 10.36648/1791-809X.21.S3.007
Niki Sadeghipor, Babak Heidari Aghdam
Importance: Coronavirus disease (COVID-19) is an infectious disease which caused by a newly discovered coronavirus Objective: The aim of this study was to investigate the effect of access to personal protective equipment on the level of stress of care workers in epidemic conditions. Design, settings, and participants: This study is hospital - based and which has been donein two stages. The first phase was performed in February 2020, when the disease had justspread and there were insufficient personal protective equipment, and the second phase wasperformed in February 2021, when it was more than 1 year since the outbreak. The disease wasover and personal protective equipment of sufficient quality was provided to the hospital staff.Census method was used to determine the number of participants in the study. In this study,the researchers conducted their research on all people. They gave the questionnaire to allfront-line care worker second-line care worker of Jam Hospital, which was 537 people. In thefirst stage, 472 questionnaires were filled out. In the second stage, 342 questionnaires werefilledout. Main outcomes and measures: We focused on symptoms of job stress in Jam Hospital staff. The same questionnaire was used in both stages. Data collection tool is a questionnaire (ENSS) Scale is a revised version of the NSS Nursing Stress Scale developed by Gary Taft andAnderson (1981). NSS is the first tool designed to measure nursing stress instead of overall jobstress. Thirty-four items of the NSS questionnaire measure the frequency and main sources ofstressin thepatientcaresituation. Results: In the first stage of the research, the level of satisfaction with the quality and availability of personal protective equipment Was 2.9%, stress level was high in 69.6% of employees (stress level was high in 65.3% of front line employees and 74% of second line employees).In the second phase of the study, when the level of employee satisfaction with personal protective equipment reached 97.3%, the level of stress was high in 44.1% of employees (the level of stress was high in 57.2% of front line employees and 31.1% of second line employees). That is, it decreased by 25.5%. In both stages of the research, the amount of stress has a significant relationship with the place of work (first stage p valu=0.013 , second stage p valu= 0.01) and there is no significant relationship between the amount of stress, gender, shift work and education
重要性:新型冠状病毒病(COVID-19)是一种由新发现的冠状病毒引起的传染病。目的:本研究的目的是调查疫情条件下护理人员获得个人防护用品对压力水平的影响。设计、环境和参与者:本研究以医院为基础,分两个阶段进行。第一阶段是在2020年2月开展的,当时疾病刚刚传播,个人防护装备不足;第二阶段是在2021年2月开展的,当时疫情已过去一年多。疾病已经结束,医院工作人员获得了质量足够的个人防护装备。采用人口普查方法确定研究参与者的人数。在这项研究中,研究人员对所有人进行了研究。他们将问卷发放给Jam医院的所有一线护理员和二线护理员,共537人。第一阶段共填写问卷472份。第二阶段共填写问卷342份。主要结果和措施:我们重点研究了Jam医院员工的工作压力症状。在两个阶段都使用了相同的问卷。ENSS量表是Gary Taft和anderson(1981)在NSS护理压力量表的基础上修订而成的。NSS是第一个用来测量护理压力而不是整体工作压力的工具。NSS问卷共34个项目测量患者护理状况中压力的频率和主要来源。结果:第一阶段对个人防护用品质量和可得性的满意度为2.9%,压力水平高的员工占69.6%(一线员工压力水平高的占65.3%,二线员工压力水平高的占74%)。在研究的第二阶段,当员工对个人防护装备的满意度达到97.3%时,44.1%的员工压力水平较高(57.2%的一线员工压力水平较高,31.1%的二线员工压力水平较高)。也就是说,下降了25.5%。在两阶段的研究中,压力量与工作地点有显著的关系(第一阶段p值=0.013,第二阶段p值=0.01),压力量与性别、轮班工作和学历之间没有显著的关系
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引用次数: 0
A Review of Novel Coronavirus Infection: COVID-19 新型冠状病毒感染:COVID-19
Pub Date : 2021-01-01 DOI: 10.36648/1791-809X.21.S3.011
Neeraj Kumar, P. Singh, R. Dewan, Neihenuo Chuzho, Shreya Chauhan, K. Khayyam
The re-emergence of novel coronavirus variant has grappled the world and imposed a halt across the globe. Since, its identification as a novel pathogen, the SARS-Coronavirus-2 has caused more than 2 million deaths worldwide. This novel virus against which humans have vastly variable immune response is still expanding its reach all over the globe. Hence, it is really critical to understand the important facts about such a lethal entity. Here, in this review, we bring together the pieces of the puzzle to understand the origin, epidemiology, pathogenesis, prevention and treatment strategies of this novel disease COVID-19. Important references to the previous SARS-coronavirus have been made to better understand the re-emergence pattern. This comparison will also help us to understand the crucial drivers of such re-emergence and the important lessons that we need to learn for prevention of any such future outbreaks.
新型冠状病毒变体的重新出现震惊了世界,并在全球范围内造成了停顿。自被确定为新型病原体以来,sars -冠状病毒-2已在全球造成200多万人死亡。人类对这种新型病毒的免疫反应差异很大,但这种病毒仍在全球范围内蔓延。因此,了解这种致命实体的重要事实是至关重要的。在本文中,我们将这些线索整合起来,以了解COVID-19这种新型疾病的起源、流行病学、发病机制、预防和治疗策略。为了更好地理解再次出现的模式,研究人员对之前的sars冠状病毒进行了重要参考。这种比较还将有助于我们了解这种重新出现的关键驱动因素,以及我们为预防未来任何此类疫情需要吸取的重要教训。
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引用次数: 0
Using Expandable Micro-Motor Bur (EMB) forExtraction of Molar Tooth Root of Dog's UpperJaw 用可膨胀式微型齿钳(EMB)拔除犬上颌骨臼齿根
Pub Date : 2021-01-01 DOI: 10.36648/1791-809X.15.3.822
Shahriar Hadaegh
Extraction of a broken tooth root is often a traumatic involvement for both the specialist and the patient. To extract broken roots, generally, invasive approaches as open window surgeries or mucoperiosteal flap and/or removal of buccal bone are performed. Expandable micro-motor bur (EMB) is a practical dental instrument proposed for the removal of broken teeth roots that cannot be extracted by the routine closed methods. The device comprises a micro-motor, spacers, needles, bur base, and a round bur that drills halfway through the root canal, expands to make a spherical cavity around itself, and behaves as an efficient extraction aiding anchor. The utilization of EMB would introduce a new technique in the removal of broken teeth roots in which surgical trauma is minimized and so are post-extraction disorders. The use of EMB would also eliminate surgical invasion to the surrounding tissues, and it would eliminate profound hand forces by the practitioner, consequently reduces stress for both the practitioner and the patient. It would also eliminate high-risk aftermaths of the surgery such as operative morbidity (due to bone loss), maxillary sinus exposure, and probable need for additional surgery which are some of the implications of the conventional open access approaches. We have tested the prototype of EMB on the molar tooth root of a dog in his upper jaw (M1) in the Medical Sciences and Technologies Research Institute of Shahid Beheshti University. No injuries to the buccal bone and surrounding nerves were observed and the root was successfully extracted. Further studies are needed to confirm its effectiveness in clinical cases.
对专家和病人来说,拔牙往往是一种创伤性的过程。为了提取断根,通常采用开窗手术或粘膜膜瓣和/或去除颊骨等侵入性方法。可膨胀式微马达齿槽是一种实用的齿科器械,用于常规封闭方法无法拔除的断牙根。该设备由微型马达、垫片、针、牙槽底座和圆形牙槽组成,圆形牙槽在根管中钻出一半,在其周围扩展成球形腔,并作为有效的拔牙辅助锚。EMB的应用将引入一种新的技术,可以最大限度地减少手术创伤和拔牙后的疾病。EMB的使用还可以消除手术对周围组织的侵犯,并且可以消除医生的手部压力,从而减少医生和病人的压力。它还可以消除手术的高风险后遗症,如手术并发症(由于骨质流失),上颌窦暴露,以及可能需要额外的手术,这些都是传统开放入路的一些影响。我们已经在Shahid Beheshti大学医学科学和技术研究所的一只狗的上颌(M1)的臼齿根上测试了EMB的原型。未见颊骨及周围神经损伤,根成功拔出。需要进一步的研究来证实其在临床病例中的有效性。
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引用次数: 0
Case Report on PeutzJegherandrsquo;s Syndrome (PJS) PJS综合征1例报告
Pub Date : 2021-01-01 DOI: 10.36648/1791-809X.21.15.840
Samruddhi S Bhakare
Peutz - Jeghers syndrome is an autosomal dominant disease, with an incidence of 1/15,000 characterised by hamartomatous polyps of the gastrointestinal tract, melanin deposits in the lips, buccal mucosa, perioral area and/or facial skin and a family history of PJS. The author reports a case of PJS in a 9 year old child admitted to a super specialty hospital in India, who presented with complaints of recurrent cramping in abdomen, abdominal pain, vomiting, loss of appetite and oral lesions. The USG and CT scan abdomen revealed multiple polyps in the small intestine. Laprotomy was done, but the child had recurrent admission in hospital due to constipation and vomiting and burning sensation in oral cavity with oral lesions. This report describes about this rare condition.
Peutz - Jeghers综合征是一种常染色体显性遗传病,发病率为1/15,000,特征为胃肠道错构瘤性息肉,嘴唇、颊黏膜、口周区和/或面部皮肤黑色素沉积,以及PJS家族史。作者报告了印度一家超级专科医院收治的一名9岁儿童PJS病例,他的主诉是腹部反复痉挛、腹痛、呕吐、食欲不振和口腔病变。腹部超声心动图及CT显示小肠多发息肉。患儿行剖腹手术,但因便秘、呕吐、口腔烧灼感伴口腔病变反复入院。本报告描述了这种罕见的情况。
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引用次数: 0
The Cost of Caring: ICU workload stressors and the Saudi Arabian nurse 护理成本:ICU工作量压力源与沙特阿拉伯护士
Pub Date : 2021-01-01 DOI: 10.36648/1791-809X.15.2.811
K. Chetty
Purpose: The purpose of this paper is to share insights, research findings and discuss key issues related to workload factors and their influence on the wellbeing of ICU nurses working in a Saudi Arabian hospital. Design/methodology/approach: The authors used a mixed method approach and using a convergent parallel mixed methods design which included separate analysis of the quantitative and the qualitative data, which were collected separately. Within this mixed methods design, the two different types of the data were synthesized for a deeper understanding of the current topic.his paper will focus on the qualitative dataset of the study. A purposive, non-probability sampling strategy was used to recruit nurses to participate in the semi-structured interviews about their workplace experiences.All consenting registered nurses, with a current and valid Saudi Council Registration, who were able to speak English, were included in the study. Tesch’s method of data analysis was used to code and categorize data to construct a shared understanding reflective of the experiences of participants and the researcher as both constructing the meanings given. Findings: The findings from the study were aligned to the JDR Model and provided evidence that ICU nurses experienced various workload factors influencing their wellbeing and productivity. These high job demands lead to strain and health impairment, associated with decreased job satisfaction amongst staff working in the ICUs of Saudi Arabian hospitals. The researcher was therefore able to propose and develop guidelines for the implementation of a comprehensive managerial framework that explicated workload factors and its influence on well-being among the ICU nurses. Research limitations/implications: The limitation that was faced by the researcher was the timeline for conducting the current research, which was governed by the University’s policies and protocol. The recruitment of participants, included ICU nurses within a group of critical care units of one hospital and excluded nurse managers. This could potentially limit the generalizability of the findings to managers at other clinical areas in the hospital regarding their perceptions of the workload and well-being among nurses in general. Despite some of these limitations, the following conclusions could be drawn and recommendations made based on these conclusions. Practical implications: Healthcare organisation across the globe is challenged to achieve nurse workforce stability, safety, and well-being. It was evident that the participants experienced many workload challenges that influenced their wellbeing within the various ICUs. This study sets out the key messages for health care managers to empower and to meet the needs of ICU nurse related to health and well-being. The findings formed the foundation for management contribution to provide improved and seamless support to the health and well-being of ICU nurses. This approach is a guide to support
目的:本文的目的是分享见解,研究成果,并讨论与工作量因素及其对沙特阿拉伯医院ICU护士福祉的影响相关的关键问题。设计/方法/方法:作者采用混合方法方法,并采用收敛并行混合方法设计,其中包括分别分析定量和定性数据,这些数据分别收集。在这种混合方法设计中,为了更深入地理解当前主题,将两种不同类型的数据进行了综合。他的论文将侧重于研究的定性数据集。采用有目的的非概率抽样策略,招募护士参加有关其工作经历的半结构化访谈。所有同意注册的护士,具有当前有效的沙特理事会注册,会说英语,都包括在研究中。Tesch的数据分析方法被用来对数据进行编码和分类,以构建一个共同的理解,反映参与者和研究者的经验,作为构建给定的意义。研究结果:研究结果与JDR模型一致,并提供证据表明ICU护士经历了各种影响其健康和生产力的工作量因素。这些高工作要求导致紧张和健康受损,与在沙特阿拉伯医院重症监护病房工作的工作人员工作满意度下降有关。因此,研究人员能够提出并制定指导方针,以实施一个全面的管理框架,明确工作量因素及其对ICU护士幸福感的影响。研究限制/影响:研究人员面临的限制是进行当前研究的时间表,这是由大学的政策和协议管理的。招募的参与者包括一家医院重症监护病房组的ICU护士,不包括护士管理人员。这可能会限制研究结果的推广到医院其他临床领域的管理人员关于他们对护士工作量和幸福感的看法。尽管存在这些局限性,但可以得出以下结论并根据这些结论提出建议。实际影响:全球医疗保健组织面临着实现护士劳动力稳定、安全和福祉的挑战。很明显,参与者经历了许多工作量挑战,影响了他们在各个icu内的健康。本研究为卫生保健管理人员提供了关键信息,以增强和满足ICU护士与健康和福祉相关的需求。这些发现为管理贡献奠定了基础,为ICU护士的健康和福祉提供了改进和无缝的支持。这种方法是一种指导,支持护士与所有关键专业人员和利益相关者合作,为护士和他们所照顾的患者提供更好的生活质量和健康结果。原创性/价值:本文探讨了沙特阿拉伯ICU护士所经历的工作量因素的各个维度及其对其健康的影响。作者能够在一个多元文化的人口基数中,从国家和国际的角度来探索这些维度。
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引用次数: 2
Sero-prevalence of IgG and IgA AntispermAntibodies in Men with Infertility AttendingTwo Major Hospitals in Zaria, Nigeria 尼日利亚扎里亚两大医院男性不育症患者血清IgG和IgA抗精子抗体的流行情况
Pub Date : 2021-01-01 DOI: 10.36648/1791-809X.21.15.837
Oduma Audu, B. Musa, Mukhtar Abdulmajid Adeiza, A. Muhammed, A. Ahmad, B. Ega, Suraju Ahmad Opaluwa, B. Shuaib
Background: Antisperm antibodies (ASA) have been implicated in some male with infertility especially those in which a definite cause could not be found. Also, some studies have attributed a causal relationship to the presence of antisperm antibodies and male infertility. Objective: This study investigated the prevalence of serum antisperm antibodies in men with infertility seen in two Hospitals in Zaria, Nigeria Materials and Methods: A total of 91 infertile men and 45 fertile men (as controls) were enrolled and follow up for 5 months. Blood samples and semen were collected, processed and analysed for serum IgA and IgG ASA using ELISA kits. Results: The study revealed the sero-prevalence of antisperm antibodies among infertile men in Zaria to be 57.1%, which varied significantly with that of the fertile male (11.1%). The prevalence of IgA and IgG antisperm antibodies were significantly higher in infertile male compared to fertile male (27.5% vs 4.4% for IgA ASA; 53.8% vs 8.9% for IgG ASA). Conclusion: The study demonstrated that IgA and IgG ASA are associated with male infertility in Zaria and as such screening for serum antisperm antibodies in the evaluation of men infertility is recommended in our environment.
背景:抗精子抗体(ASA)已涉及一些男性不育,特别是那些在一个明确的原因不能找到。此外,一些研究认为抗精子抗体的存在与男性不育有因果关系。目的:调查尼日利亚扎里亚两家医院男性不育症患者血清抗精子抗体的流行情况。材料和方法:入选91例不育症男性和45例有生育能力男性(对照组),随访5个月。采集血样和精液,用ELISA试剂盒处理和分析血清IgA和IgG ASA。结果:扎里亚不育男性血清抗精子抗体阳性率为57.1%,与可育男性血清抗精子抗体阳性率(11.1%)差异显著。与可育男性相比,不育男性IgA和IgG抗精子抗体的患病率明显更高(27.5% vs 4.4%;IgG ASA 53.8% vs 8.9%)。结论:本研究表明,IgA和IgG ASA与Zaria男性不育有关,因此在我国环境下推荐筛查血清抗精子抗体来评估男性不育。
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引用次数: 1
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