Pub Date : 2021-01-01DOI: 10.36648/1791-809X.21.15.838
M. Fereidouni, N. Rezaei
The COVID-19 crisis is ongoing and there is no clear prospect for overcoming it. This crisis has revealed many problems and deficiencies in different sectors, particularly the health system and more importantly in communication, decision-making, and executive systems not only at the national, but also at the international level. For better confrontation future crises, identifying these pitfalls and resolving them is very important; in this regard, scientific societies play a very fundamental role. Firstly, they should perform deep reforms in their structure for better efficacy, coordination, and impact. It is to be hoped that scientific societies have learned enough from this pandemic to be ready for the next one. There is a need to develop a suitable model for more effective and coordinated approaches in the future, amid to reduce the casualties and more appropriate responses to health crises in a shorter period of time and with greater efficiency. In this manuscript we proposed a model for scientific societies to improve their impacts during health crises. This includes establishing preevent capabilities, in crisis actions, and recommendations to be taken after the current crisis and before the next one.
{"title":"Improving the Role of Medical Scientific Societies during Health Crises","authors":"M. Fereidouni, N. Rezaei","doi":"10.36648/1791-809X.21.15.838","DOIUrl":"https://doi.org/10.36648/1791-809X.21.15.838","url":null,"abstract":"The COVID-19 crisis is ongoing and there is no clear prospect for overcoming it. This crisis has revealed many problems and deficiencies in different sectors, particularly the health system and more importantly in communication, decision-making, and executive systems not only at the national, but also at the international level. For better confrontation future crises, identifying these pitfalls and resolving them is very important; in this regard, scientific societies play a very fundamental role. Firstly, they should perform deep reforms in their structure for better efficacy, coordination, and impact. It is to be hoped that scientific societies have learned enough from this pandemic to be ready for the next one. There is a need to develop a suitable model for more effective and coordinated approaches in the future, amid to reduce the casualties and more appropriate responses to health crises in a shorter period of time and with greater efficiency. In this manuscript we proposed a model for scientific societies to improve their impacts during health crises. This includes establishing preevent capabilities, in crisis actions, and recommendations to be taken after the current crisis and before the next one.","PeriodicalId":12868,"journal":{"name":"Health science journal","volume":"48 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90627964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.36648/1791-809X.15.1.789
S. Kalpana, S. Bhuminathan, Prasanth Bk
The main industrial sources of emissions have decreased or completely stopped during the lockdown era, which helped reduce the pollution load [10]It is also found that, the concentration of pH, electric conductivity [EC], DO, BOD and chemical oxygen demand [COD] has reduced almost 1-10%, 3366%, 45-90%, and 33-82% respectively in different monitoring stations during the lockdown in comparison to the pre-lockdown period [11] [ ]the number of flights and vehicular movements around the world has significantly decreased due to travel restrictions, which have consequently lowered the level of noise pollution [ ]a sudden rise and proper management of hazardous waste has become an important problem for the local waste management authorities * According to recent published literature, SARS-CoV-2 viruses are reported to exist on cardboard every day and on plastics and stainless steel for up to 3 days [19] [ ]hospitalgenerated waste should be adequately handled to minimise more infection and environmental contamination, which is now a global concern * Though, experts and responsible authorities suggest for the proper disposal and segregation of household organic waste and plastic based protective equipment [hazardous medical waste], but mixing up these wastes increases the risk of disease transmission, and exposure to the virus of waste workers [20] * Massive amounts of disinfectants have recently been used to destroy the SARS-CoV-2 virus in highways, industrial, and residential areas [ ]after the Partition of India in 1947, India witnessed the second-largest reverse mass in its history
{"title":"Reality of Life and Environmental Changes after COVID-19 Pandemic in India","authors":"S. Kalpana, S. Bhuminathan, Prasanth Bk","doi":"10.36648/1791-809X.15.1.789","DOIUrl":"https://doi.org/10.36648/1791-809X.15.1.789","url":null,"abstract":"The main industrial sources of emissions have decreased or completely stopped during the lockdown era, which helped reduce the pollution load [10]It is also found that, the concentration of pH, electric conductivity [EC], DO, BOD and chemical oxygen demand [COD] has reduced almost 1-10%, 3366%, 45-90%, and 33-82% respectively in different monitoring stations during the lockdown in comparison to the pre-lockdown period [11] [ ]the number of flights and vehicular movements around the world has significantly decreased due to travel restrictions, which have consequently lowered the level of noise pollution [ ]a sudden rise and proper management of hazardous waste has become an important problem for the local waste management authorities * According to recent published literature, SARS-CoV-2 viruses are reported to exist on cardboard every day and on plastics and stainless steel for up to 3 days [19] [ ]hospitalgenerated waste should be adequately handled to minimise more infection and environmental contamination, which is now a global concern * Though, experts and responsible authorities suggest for the proper disposal and segregation of household organic waste and plastic based protective equipment [hazardous medical waste], but mixing up these wastes increases the risk of disease transmission, and exposure to the virus of waste workers [20] * Massive amounts of disinfectants have recently been used to destroy the SARS-CoV-2 virus in highways, industrial, and residential areas [ ]after the Partition of India in 1947, India witnessed the second-largest reverse mass in its history","PeriodicalId":12868,"journal":{"name":"Health science journal","volume":"6 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77063107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.36648/1791-809X.21.15.827
A. Dumitrescu, R. Cobzaru, C. Rîpă, Roxana-Maria Barbu, C. Costea, M. Tanase, V. Șorodoc, L. Hilițanu, L. Gavril, A. Sava
Aim and background: Because circle of Willis provides the best collateral source of blood flow in arterial occlusive disorders, identifying anatomical variants that could be present at this level is especially essential in planning surgery for cerebral aneurysms. Given the fact that the frequency of these anatomical variations of circle of Willis has not yet been sufficiently evaluated in the Romanian population until presently, we have conducted a research in a regional health unit, where there are admitted patients with neurological and neurosurgical diseases living in the North-Eastern region of Romania, in order to identify morphological features of the constituent vessels of fresh circles of Willis at the moment of the autopsy of the deceased patients in the Emergency Clinical Hospital „Prof. dr. N. Oblu” Ia�?i. There has been noted the presence or absence, variations of shape, position or trajectory of each arterial segment. In the end, our results were compared with those from literature in order to identify some particular pattern of this anastomotic structure in the population of the North-Eastern region of Romania. Materials and Methods: The present research is a descriptive in-hospital observational study on the morphology of the circles of Willis of 96 patients who died of various medical causes in the Emergency Clinical Hospital “Prof. dr. N. Oblu” Ia�?i, in a period of 30 months, to whom an anatomo-clinical autopsy was performed in order to determine the cause of death. Results: From the total of 96 available human brains, 28 cases (29.17%) were classified as ”atypical” as they expressed anatomical variants of the constituent vessels. Among the 28 deceased patients with atypical CW, the M: F ratio was 1.15 and the average age of the entire group was 61.78 years. From the 28 atypical circles of Willis, 19 of them (67.86%) presented multiple anatomical variants, and only 9 cases (32.14%) had a single anatomical variant. Among multiple variants of the vessels of the circle of Willis, we identified the association of two (32.14%), three (25%), four (7.14%), or five (3.57%) anatomical variants of those seven constituent arteries. Eight types of variations of the constituent arteries of the circle of Willis were identified: absence of a vessel, partial fetal ACP, hypoplasia, duplication, fenestration, azygos, common trunk with another vessel at the origin, longer length with sinuous trajectory. Conclusion: Our results showed intermediate values between those reported in various studies performed on circles of Willis obtained at autopsies. These differences can be interpreted as possible peculiarities of the population in North-Eastern region of Romania. Unlike all other studies with which we compared the results obtained, in our research two thirds of cases with variations presented multiple anatomical variants, including five simultaneous variants.
{"title":"A Morphological Study of Anatomical Variations in 96 Circles of Willis: an Autopsic Evaluation and Literature Review","authors":"A. Dumitrescu, R. Cobzaru, C. Rîpă, Roxana-Maria Barbu, C. Costea, M. Tanase, V. Șorodoc, L. Hilițanu, L. Gavril, A. Sava","doi":"10.36648/1791-809X.21.15.827","DOIUrl":"https://doi.org/10.36648/1791-809X.21.15.827","url":null,"abstract":"Aim and background: Because circle of Willis provides the best collateral source of blood flow in arterial occlusive disorders, identifying anatomical variants that could be present at this level is especially essential in planning surgery for cerebral aneurysms. Given the fact that the frequency of these anatomical variations of circle of Willis has not yet been sufficiently evaluated in the Romanian population until presently, we have conducted a research in a regional health unit, where there are admitted patients with neurological and neurosurgical diseases living in the North-Eastern region of Romania, in order to identify morphological features of the constituent vessels of fresh circles of Willis at the moment of the autopsy of the deceased patients in the Emergency Clinical Hospital „Prof. dr. N. Oblu” Ia�?i. There has been noted the presence or absence, variations of shape, position or trajectory of each arterial segment. In the end, our results were compared with those from literature in order to identify some particular pattern of this anastomotic structure in the population of the North-Eastern region of Romania. Materials and Methods: The present research is a descriptive in-hospital observational study on the morphology of the circles of Willis of 96 patients who died of various medical causes in the Emergency Clinical Hospital “Prof. dr. N. Oblu” Ia�?i, in a period of 30 months, to whom an anatomo-clinical autopsy was performed in order to determine the cause of death. Results: From the total of 96 available human brains, 28 cases (29.17%) were classified as ”atypical” as they expressed anatomical variants of the constituent vessels. Among the 28 deceased patients with atypical CW, the M: F ratio was 1.15 and the average age of the entire group was 61.78 years. From the 28 atypical circles of Willis, 19 of them (67.86%) presented multiple anatomical variants, and only 9 cases (32.14%) had a single anatomical variant. Among multiple variants of the vessels of the circle of Willis, we identified the association of two (32.14%), three (25%), four (7.14%), or five (3.57%) anatomical variants of those seven constituent arteries. Eight types of variations of the constituent arteries of the circle of Willis were identified: absence of a vessel, partial fetal ACP, hypoplasia, duplication, fenestration, azygos, common trunk with another vessel at the origin, longer length with sinuous trajectory. Conclusion: Our results showed intermediate values between those reported in various studies performed on circles of Willis obtained at autopsies. These differences can be interpreted as possible peculiarities of the population in North-Eastern region of Romania. Unlike all other studies with which we compared the results obtained, in our research two thirds of cases with variations presented multiple anatomical variants, including five simultaneous variants.","PeriodicalId":12868,"journal":{"name":"Health science journal","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82183410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.36648/1791-809X.15.3.818
Àlex, ra Androni
Amidst the wake of the Ebola virus disease (EVD) that has been ravaging parts of Africa, severalisolative measures are followed to halt the spread of the epidemic. Many of these measures are yet drastic and directly affect the fundamental rights of individuals involved. The EVD outbreaks open a big discussion on public health and human rights. This article focuses on the human rights violated in the battle of EVD and considers how these are similar, yet can be avoided in the management of COVID-19.
{"title":"Human Right Violations in the 2018 EbolaOutbreak: What can Improve in Covid-19Isolation Protocols?","authors":"Àlex, ra Androni","doi":"10.36648/1791-809X.15.3.818","DOIUrl":"https://doi.org/10.36648/1791-809X.15.3.818","url":null,"abstract":"Amidst the wake of the Ebola virus disease (EVD) that has been ravaging parts of Africa, severalisolative measures are followed to halt the spread of the epidemic. Many of these measures are yet drastic and directly affect the fundamental rights of individuals involved. The EVD outbreaks open a big discussion on public health and human rights. This article focuses on the human rights violated in the battle of EVD and considers how these are similar, yet can be avoided in the management of COVID-19.","PeriodicalId":12868,"journal":{"name":"Health science journal","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89034360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.36648/1791-809X.15.1.784
A. Dumitrescu, A. Sava, D. Turliuc, A. Cucu, R. Șufaru, I. Gotcă, I. Grierosu, Ş. Turliuc
Objective: To identify the clinical consequences of bilateral hypoplasia of the posterior communicating arteries (PCoAs) in order to provide a clue to neurosurgeons and neurologists in their work to diagnose and treat patients with stroke symptoms. Material and methods: We performed an anatomical retrospective study on gross morphology of 98 circles of Willis (CW) that were identified at the time of the autopsies made on patients who have died in the "Prof. dr. N. Oblu” Emergency Clinical Hospital Iasi, Romania, the main neurological and neuro-surgical healthcare Centre in the region of North-Eastern Romania, for a period of three years. Demographical and autopsic data, as well as photographic images were taken from the registers and archives of the Pathology Department. Only CWs with bilateral hypoplasia of PCoA without any other associated anatomical abnormalities were studied. Results: In 5 cases (5.12%) we identified bilateral hypoplasia of PCoAs. Male: Female ratio was 3: 2. The average age was 63.5 years. 80% of cases died of ischemic or haemorrhagic stroke, but 10% died of heart disease. In 2 (40%) cases, one of the two PCoAs presented aplasia and the other was hypoplastic, an event related to frontal lobe strokes on the same side. In the other two (40%) cases in which both arteries were hypoplastic, the cause of death was ischemic stroke located in the brainstem. In only one case (20%), even in the presence of bilateral hypoplasia of PCoAs, the cause of death was non-neurological. Conclusion: Even if literature claims that PCoA hypoplasia becomes a risk factor for ischemic stroke only in the presence of ipsilateral internal carotid artery (ICA) occlusion, in our study we found that aplasia of one of the two PCoAs associated with hypoplasia of the controlateral artery caused ischemic stroke in the brainstem, thus revealing the role of PCoAs in ensuring the posterior circulation in case of occlusion of the vertebro-basilar system.
{"title":"An Autopsic Study on Bilateral Hypoplasiaof the Posterior Communicating Arteriesin Cerebrovascular Diseases","authors":"A. Dumitrescu, A. Sava, D. Turliuc, A. Cucu, R. Șufaru, I. Gotcă, I. Grierosu, Ş. Turliuc","doi":"10.36648/1791-809X.15.1.784","DOIUrl":"https://doi.org/10.36648/1791-809X.15.1.784","url":null,"abstract":"Objective: To identify the clinical consequences of bilateral hypoplasia of the posterior communicating arteries (PCoAs) in order to provide a clue to neurosurgeons and neurologists in their work to diagnose and treat patients with stroke symptoms. Material and methods: We performed an anatomical retrospective study on gross morphology of 98 circles of Willis (CW) that were identified at the time of the autopsies made on patients who have died in the \"Prof. dr. N. Oblu” Emergency Clinical Hospital Iasi, Romania, the main neurological and neuro-surgical healthcare Centre in the region of North-Eastern Romania, for a period of three years. Demographical and autopsic data, as well as photographic images were taken from the registers and archives of the Pathology Department. Only CWs with bilateral hypoplasia of PCoA without any other associated anatomical abnormalities were studied. Results: In 5 cases (5.12%) we identified bilateral hypoplasia of PCoAs. Male: Female ratio was 3: 2. The average age was 63.5 years. 80% of cases died of ischemic or haemorrhagic stroke, but 10% died of heart disease. In 2 (40%) cases, one of the two PCoAs presented aplasia and the other was hypoplastic, an event related to frontal lobe strokes on the same side. In the other two (40%) cases in which both arteries were hypoplastic, the cause of death was ischemic stroke located in the brainstem. In only one case (20%), even in the presence of bilateral hypoplasia of PCoAs, the cause of death was non-neurological. Conclusion: Even if literature claims that PCoA hypoplasia becomes a risk factor for ischemic stroke only in the presence of ipsilateral internal carotid artery (ICA) occlusion, in our study we found that aplasia of one of the two PCoAs associated with hypoplasia of the controlateral artery caused ischemic stroke in the brainstem, thus revealing the role of PCoAs in ensuring the posterior circulation in case of occlusion of the vertebro-basilar system.","PeriodicalId":12868,"journal":{"name":"Health science journal","volume":"590 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78130094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.36648/1791-809X.21.S3.010
B. Patil
Jaggery is rich in iron and foliate that help in preventing anemia by ensuring that a normal level of red blood cells is maintained. "With the growing awareness in the Indian market about eating right, avoiding refined products and replacing those refined sugars with natural sweeteners, chefs and nutritionists have started and reinventing healthy recipes using jaggery, coconut sugar, or even date syrups etc as sugar alternatives," adds Kutteri. References 1 Lamdande AG, Khabeer ST, Kulathooran R, DasappaI (2018) Effect of Replacement of sugar with jaggery on pasting properties of Wheat flour, Physico-sensory and storage characteristics of Muffins.
{"title":"Health Benefits of Jaggery Tea on the Account of COVID-19","authors":"B. Patil","doi":"10.36648/1791-809X.21.S3.010","DOIUrl":"https://doi.org/10.36648/1791-809X.21.S3.010","url":null,"abstract":"Jaggery is rich in iron and foliate that help in preventing anemia by ensuring that a normal level of red blood cells is maintained. \"With the growing awareness in the Indian market about eating right, avoiding refined products and replacing those refined sugars with natural sweeteners, chefs and nutritionists have started and reinventing healthy recipes using jaggery, coconut sugar, or even date syrups etc as sugar alternatives,\" adds Kutteri. References 1 Lamdande AG, Khabeer ST, Kulathooran R, DasappaI (2018) Effect of Replacement of sugar with jaggery on pasting properties of Wheat flour, Physico-sensory and storage characteristics of Muffins.","PeriodicalId":12868,"journal":{"name":"Health science journal","volume":"26 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85911262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.36648/1791-809X.15.2.805
Mafruha Kumkum, ni Akter Rokeya, Md. Rafat Tahsin, E. Haque, T. I. Tithi, J. A. Chowdhury, Shaila Kabir, A. Choudhury, Md. Shah Amran
Metabolic disorder diabetes results from an alteration of the secretion or action of insulin. Trigonella foenum-graecum is a traditionally used specimen since ancient times. We aimed to investigate the hypoglycemic potential of ethanolic extract of T. foenum-graecum seed powder solution both in a dose and source-dependent manner as well as to fathom out its safety profile so that this plant can be used to ameliorate diabetes. Diabetes was induced in the rat model via intraperitoneal injection of alloxan (150 mg/kg). Ethanolic extract of T. foenum-graecum was administered to rats’ belonged to different groups. Blood glucose levels were assessed periodically and the safety profiles were evaluated through assessment of SGOT, SGPT, creatinine, and lipid profiles after sacrificing the animals. It has been evidenced that T. foenum-graecum possesses anti-diabetic activity. Furthermore, the extract is capable of reversing the disturbed pathological state towards a healthy status. Besides, these therapeutic consequences possess dose-dependent potentiality (p<0.05), further a noteworthy source dependent (p<0.01) response were experienced. It may confer that the inconsistency associated with the remedial impacts between 2 same doses belonged to two distinct sources are due to accuracy of lab-based preparation, geographic area of cultivation, and also the season of collection. Apart from that, the visual and statistical inspections have evidence that the medium and the high dose are imparting almost indistinguishable therapeutic effects. Presumably, the reason lies beneath the receptor saturation issue.
{"title":"An Evaluation of Dose and Sourcedependent Activity of Ethanolic Extractof Trigonellafoenum-graecum againstDiabetes Using Alloxan-Induced RatModel","authors":"Mafruha Kumkum, ni Akter Rokeya, Md. Rafat Tahsin, E. Haque, T. I. Tithi, J. A. Chowdhury, Shaila Kabir, A. Choudhury, Md. Shah Amran","doi":"10.36648/1791-809X.15.2.805","DOIUrl":"https://doi.org/10.36648/1791-809X.15.2.805","url":null,"abstract":"Metabolic disorder diabetes results from an alteration of the secretion or action of insulin. Trigonella foenum-graecum is a traditionally used specimen since ancient times. We aimed to investigate the hypoglycemic potential of ethanolic extract of T. foenum-graecum seed powder solution both in a dose and source-dependent manner as well as to fathom out its safety profile so that this plant can be used to ameliorate diabetes. Diabetes was induced in the rat model via intraperitoneal injection of alloxan (150 mg/kg). Ethanolic extract of T. foenum-graecum was administered to rats’ belonged to different groups. Blood glucose levels were assessed periodically and the safety profiles were evaluated through assessment of SGOT, SGPT, creatinine, and lipid profiles after sacrificing the animals. It has been evidenced that T. foenum-graecum possesses anti-diabetic activity. Furthermore, the extract is capable of reversing the disturbed pathological state towards a healthy status. Besides, these therapeutic consequences possess dose-dependent potentiality (p<0.05), further a noteworthy source dependent (p<0.01) response were experienced. It may confer that the inconsistency associated with the remedial impacts between 2 same doses belonged to two distinct sources are due to accuracy of lab-based preparation, geographic area of cultivation, and also the season of collection. Apart from that, the visual and statistical inspections have evidence that the medium and the high dose are imparting almost indistinguishable therapeutic effects. Presumably, the reason lies beneath the receptor saturation issue.","PeriodicalId":12868,"journal":{"name":"Health science journal","volume":"67 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89058002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.36648/1791-809X.21.S3.001
Zhangmengxue Lei
Objective: Explore the performance of different test methods in detecting COVID-19 antibodies and antigens. Methods: Compare the results of different test methods on samples from novel coronavirus pneumonia patients, and randomly select some of the confirmed samples after gradient dilution to detect the sensitivity of the test products. The sample used for rapid detection of COVID-19 antigen was nasal swab. Three kinds of sample used in the detection of novel coronavirus antibodies were venipuncture/ fingerstick whole blood, serum and plasma. Results: The detection rate of covid-19 antibody increased with the increase of the onset time of patients, while the detection rate of antigen decreased gradually, which was in line with the nature of antigen and antibody in the human body. Conclusion: In view of the advantages of antibody and antigen detection, such as convenient and sample collection, high throughput, low workload, high reproducibility and low cost, we hope to lay a scientific foundation for the horizontal comparison of the data of products (Abbott, Roche, Healgen, AllTest, Citest, Siemens, Lepu, Wondfo) obtained in the research and practical application of epidemic prevention and control of COVID-19.
{"title":"Different Methods of COVID-19 Detection","authors":"Zhangmengxue Lei","doi":"10.36648/1791-809X.21.S3.001","DOIUrl":"https://doi.org/10.36648/1791-809X.21.S3.001","url":null,"abstract":"Objective: Explore the performance of different test methods in detecting COVID-19 antibodies and antigens. Methods: Compare the results of different test methods on samples from novel coronavirus pneumonia patients, and randomly select some of the confirmed samples after gradient dilution to detect the sensitivity of the test products. The sample used for rapid detection of COVID-19 antigen was nasal swab. Three kinds of sample used in the detection of novel coronavirus antibodies were venipuncture/ fingerstick whole blood, serum and plasma. Results: The detection rate of covid-19 antibody increased with the increase of the onset time of patients, while the detection rate of antigen decreased gradually, which was in line with the nature of antigen and antibody in the human body. Conclusion: In view of the advantages of antibody and antigen detection, such as convenient and sample collection, high throughput, low workload, high reproducibility and low cost, we hope to lay a scientific foundation for the horizontal comparison of the data of products (Abbott, Roche, Healgen, AllTest, Citest, Siemens, Lepu, Wondfo) obtained in the research and practical application of epidemic prevention and control of COVID-19.","PeriodicalId":12868,"journal":{"name":"Health science journal","volume":"47 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88197629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.36648/1791-809X.21.15.835
Silvia Maria Sobral Oliveira, Allan Mateus da Silva Lima, Carolina Veiga Pereira, Emily Macedo Mainardi, Gabrielle Woan Hua Seifert Wu, Isis Pinheiro Damasceno, Luciane Lobato Sobral Santos, Rodrigo Santiago Barbosa Rocha, Maryana Therumy Kabuki, Larissa Salgado de Oliveira Rocha
Objective: To evaluate the Balance Concept influence upon balance and quality of life of unilateral vestibular hypofunction (UVH) patients and their self-perception. Method: 6 patients were selected, both sexes and mean ages 55,33 ± 20,66, and the mean time of UVH basis diagnosis of 4,33 ± 3,32 years, were submitted to exercises based on Balance Concept three times a week, during 12 sessions and assessed by the Mini-Mental State Examination (MMSE), Dizzines Handicap Inventory questionnaire and Berg Balance Scale. Shapiro Wilk test and T test sample data (p<0,05) were used. Results: It was observed on Berg Balance Scale significant increase by comparing pre-treatment over post-treatment (p=0,0059), likewise on Dizzines Handicap Inventory scale, which was significant if comparing pre-treatment and post-treatment rates (p=<0.0001), in the same way, it was reported by the patients, an improvement after the proposed protocol. Conclusion: The used protocol based on the Balance Concept in this study helped the reduction of dizziness and balance improvement on unilateral vestibular hypo function patients, reflecting directly on their daily activities.
{"title":"The Balance Concept on Unilateral VestibularHypofunction Patients Changes the Balance andQuality of Life","authors":"Silvia Maria Sobral Oliveira, Allan Mateus da Silva Lima, Carolina Veiga Pereira, Emily Macedo Mainardi, Gabrielle Woan Hua Seifert Wu, Isis Pinheiro Damasceno, Luciane Lobato Sobral Santos, Rodrigo Santiago Barbosa Rocha, Maryana Therumy Kabuki, Larissa Salgado de Oliveira Rocha","doi":"10.36648/1791-809X.21.15.835","DOIUrl":"https://doi.org/10.36648/1791-809X.21.15.835","url":null,"abstract":"Objective: To evaluate the Balance Concept influence upon balance and quality of life of unilateral vestibular hypofunction (UVH) patients and their self-perception. Method: 6 patients were selected, both sexes and mean ages 55,33 ± 20,66, and the mean time of UVH basis diagnosis of 4,33 ± 3,32 years, were submitted to exercises based on Balance Concept three times a week, during 12 sessions and assessed by the Mini-Mental State Examination (MMSE), Dizzines Handicap Inventory questionnaire and Berg Balance Scale. Shapiro Wilk test and T test sample data (p<0,05) were used. Results: It was observed on Berg Balance Scale significant increase by comparing pre-treatment over post-treatment (p=0,0059), likewise on Dizzines Handicap Inventory scale, which was significant if comparing pre-treatment and post-treatment rates (p=<0.0001), in the same way, it was reported by the patients, an improvement after the proposed protocol. Conclusion: The used protocol based on the Balance Concept in this study helped the reduction of dizziness and balance improvement on unilateral vestibular hypo function patients, reflecting directly on their daily activities.","PeriodicalId":12868,"journal":{"name":"Health science journal","volume":"698 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83571673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.36648/1791-809X.21.15.855
S. Chakrabartty
Purpose: Effectiveness of COVID-19 vaccine is increasingly important for better immunization, sustain uptake, in the background of availability of a number of vaccines and uneven vaccination programmes with different objectives and strategies. The paper explores different measures of vaccine efficiency (VE) at population level for comparing and classifying groups of individuals in terms of risk and to find relationships between exposures and spread of disease. Methods: To review model-free measures and outcome measures of mathematical/ statistical models towards meaningful comparisons and assessment of efficiency of SARS-CoV-2 vaccine and to suggest better measures. Results: Mathematical models with unrealistic assumptions and limitations may underestimate the impact of mass vaccination. Interrupted time-series comparing trends in pre-vaccination and post-vaccine periods have wide applicability. Two suggested measures of VE are (i) difference of slopes of pre- and post-vaccination periods and (ii) Relative Risk (RR), reflecting association between the exposure and the outcome. Conclusions: VE computed from difference of slopes of two linear trends or RR facilitates statistical testing of equality of the vaccine efficiency for two different groups with available statistical tests. Measures based on ratios and proportions are simple to compute, interpret and facilitate meaningful comparisons including statistical testing of hypothesis. Such measures may be computed for sub-populations defined in terms of the factors of COVID 19 like age, gender, co-morbidities, genetic & biological factors, adaptive immunity, prior exposure to SARS-CoV-2 via infection or via vaccination, etc. Model-free measures for evaluation and models considering administration of vaccine mechanism may be considered independently. Future studies suggested.
{"title":"Measures of Efficacious COVID-19 Vaccine","authors":"S. Chakrabartty","doi":"10.36648/1791-809X.21.15.855","DOIUrl":"https://doi.org/10.36648/1791-809X.21.15.855","url":null,"abstract":"Purpose: Effectiveness of COVID-19 vaccine is increasingly important for better immunization, sustain uptake, in the background of availability of a number of vaccines and uneven vaccination programmes with different objectives and strategies. The paper explores different measures of vaccine efficiency (VE) at population level for comparing and classifying groups of individuals in terms of risk and to find relationships between exposures and spread of disease. Methods: To review model-free measures and outcome measures of mathematical/ statistical models towards meaningful comparisons and assessment of efficiency of SARS-CoV-2 vaccine and to suggest better measures. Results: Mathematical models with unrealistic assumptions and limitations may underestimate the impact of mass vaccination. Interrupted time-series comparing trends in pre-vaccination and post-vaccine periods have wide applicability. Two suggested measures of VE are (i) difference of slopes of pre- and post-vaccination periods and (ii) Relative Risk (RR), reflecting association between the exposure and the outcome. Conclusions: VE computed from difference of slopes of two linear trends or RR facilitates statistical testing of equality of the vaccine efficiency for two different groups with available statistical tests. Measures based on ratios and proportions are simple to compute, interpret and facilitate meaningful comparisons including statistical testing of hypothesis. Such measures may be computed for sub-populations defined in terms of the factors of COVID 19 like age, gender, co-morbidities, genetic & biological factors, adaptive immunity, prior exposure to SARS-CoV-2 via infection or via vaccination, etc. Model-free measures for evaluation and models considering administration of vaccine mechanism may be considered independently. Future studies suggested.","PeriodicalId":12868,"journal":{"name":"Health science journal","volume":"23 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88851463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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