Heart rhythm最新文献

{"title":"Impaired sensitivity to thyroid hormones is associated with lower heart rate in the euthyroid population","authors":"Guojie Ye MD ,&nbsp;Yingyue Zhang PhD ,&nbsp;Le Peng PhD ,&nbsp;Zhenze Yu MD ,&nbsp;Yunhe Bai MD ,&nbsp;Meishan Wu MD ,&nbsp;Dan Lu PhD ,&nbsp;Chunhua Ding PhD","doi":"10.1016/j.hrthm.2025.02.028","DOIUrl":"10.1016/j.hrthm.2025.02.028","url":null,"abstract":"<div><h3>Background</h3><div>The association of thyroid hormone sensitivity with heart rate remains unclear.</div></div><div><h3>Objective</h3><div><span>This study aims to elucidate the relationship between impaired thyroid hormone sensitivity and lower heart rate in the </span>euthyroid population.</div></div><div><h3>Methods</h3><div><span>A total of 550 participants were included. Heart rate and serum biochemicals were measured. Thyroid hormone sensitivity indices were calculated using the thyrotropin<span> index (TSHI), thyrotropin </span></span>thyroxine<span> resistance index (TT4RI), thyroid feedback quantile–based index (TFQI), Chinese-referenced parametric TFQI (PTFQI), and the ratio of free triiodothyronine<span><span> to free thyroxine (FT3/FT4 ratio). </span>Logistic regression analyses were applied to explore the relationship between thyroid hormone sensitivity indices and heart rate.</span></span></div></div><div><h3>Results</h3><div>TSHI, TT4RI, TFQI, and PTFQI were higher, and FT3/FT4 ratio was lower in participants with heart rate ≤ 60 beats/min (<em>P</em><span> &lt; .001 for all). Participants with increased TSHI, TT4RI, TFQI, and PTFQI and reduced FT3/FT4 ratio had lower heart rate (≤60 beats/min) (</span><em>P</em><span> for trend &lt; .001 for all). Odds ratios (95% confidence intervals) for TSHI, TT4RI, TFQI, PTFQI, and FT3/FT4 ratio in the highest quartile were 2.090 (1.092–4.000), 2.240 (1.151–4.361), 2.014 (1.043–3.887), 2.163 (1.123–4.166), and 0.498, (0.249–0.996), respectively, as compared with the lowest quartile after adjusting for sex, age, body mass index<span><span>, smoking, drinking, hypertension, diabetes, coronary artery disease, </span>glycated hemoglobin<span><span>, total cholesterol, low-density lipoprotein cholesterol, and </span>triglycerides.</span></span></span></div></div><div><h3>Conclusion</h3><div>Impaired sensitivity to thyroid hormones was associated with lower heart rate in euthyroid participants. Future large-scale studies are needed to confirm our findings.</div></div>","PeriodicalId":12886,"journal":{"name":"Heart rhythm","volume":"23 1","pages":"Pages 203-211"},"PeriodicalIF":5.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143476370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hybrid focal pulsed field and additional radiofrequency ablation for anterior mitral line: A novel sequential approach to improve lesion durability","authors":"Sebastian Weyand MD ,&nbsp;Viola Adam MD ,&nbsp;Matthias Beuter MD ,&nbsp;Paloma Biehler MD ,&nbsp;Patricia Hägele MD ,&nbsp;Simon Hanger MD ,&nbsp;Stephanie Löbig MD ,&nbsp;Andrei Pinchuk MD ,&nbsp;Peter Seizer MD","doi":"10.1016/j.hrthm.2025.05.073","DOIUrl":"10.1016/j.hrthm.2025.05.073","url":null,"abstract":"","PeriodicalId":12886,"journal":{"name":"Heart rhythm","volume":"23 1","pages":"Pages 218-219"},"PeriodicalIF":5.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144247497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ablation of cavotricuspid isthmus–dependent atrial flutter using a focal monopolar pulsed-field ablation catheter: Feasibility, periprocedural coronary spasms and conduction disorders","authors":"Florent I.P. Farnir MD ,&nbsp;Sevasti-Maria Chaldoupi MD, PhD ,&nbsp;Ben Hermans PhD ,&nbsp;Arne Johannessen MD, DMSc ,&nbsp;Martin Aar Haugdal MSc ,&nbsp;Martin H. Ruwald MD ,&nbsp;Tasnim Mohaissen PhD ,&nbsp;Arnela Saljic PhD ,&nbsp;Kezia Jerltorp DVM ,&nbsp;Sarah Dalgas Nissen DVM, PhD ,&nbsp;Julie Norup Hertel DVM ,&nbsp;Frédéric Farnir PhD ,&nbsp;Thomas Jespersen PhD ,&nbsp;Ulrich Schotten MD, PhD ,&nbsp;Justin G.L.M. Luermans MD, PhD ,&nbsp;Kevin Vernooy MD, PhD ,&nbsp;Jim Hansen MD, DMSc ,&nbsp;Dominik Linz MD, PhD","doi":"10.1016/j.hrthm.2025.07.001","DOIUrl":"10.1016/j.hrthm.2025.07.001","url":null,"abstract":"<div><h3>Background</h3><div>Pulsed-field ablation for the treatment of cavotricuspid isthmus (CTI)–dependent atrial flutter has been associated with coronary spasms (CS) and atrioventricular conduction disorders (CD).</div></div><div><h3>Objectives</h3><div>The purpose of this study was to evaluate the feasibility of CTI ablation using a monopolar focal pulsed-field ablation (F-PFA) catheter and to assess the risk of CS and CD during and after the procedure.</div></div><div><h3>Methods</h3><div>We prospectively enrolled patients with atrial flutter treated with an F-PFA system (CardioFocus, Marlborough, MA) or by focal radiofrequency ablation (RFA) using contact force–sensing catheters integrated into electroanatomic mapping systems. Intravenous nitroglycerin was administered prior to F-PFA. Feasibility and safety with a focus on CS or CD were assessed. In a subgroup of patients, the course of the right coronary artery and the His position were determined.</div></div><div><h3>Results</h3><div>In total, 82 patients underwent CTI ablation with F-PFA (mean age 66 ± 8 years; 15 (18%) being female; CHA₂DS₂-VA score 1.6 ± 1.3) and 27 patients underwent CTI ablation with RFA (mean age 63 ± 9 years; 4 (23%) being female; CHA₂DS₂-VA score 2 ± 1.3). For F-PFA, the rate of first-pass block was higher (93% vs 55%) and the median (interquartile range) procedure times were shorter (7 [5–11] minutes vs 17 [15–19] minutes) than for RFA. In the F-PFA group, 4 patients (5%) had transient ST-segment elevation and 2 patients (2%) had transient complete atrioventricular block during ablation. There was a small but significant prolongation of the PQ interval after CTI ablation in the F-PFA group.</div></div><div><h3>Conclusion</h3><div>CTI ablation using F-PFA is feasible, but operators should be aware of rare but critical CD and CS during the procedure, even when preventive measures such as nitroglycerin administration are used.</div></div>","PeriodicalId":12886,"journal":{"name":"Heart rhythm","volume":"23 1","pages":"Pages 105-113"},"PeriodicalIF":5.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144575357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-risk transvenous lead extraction can be safely performed in the electrophysiology laboratory","authors":"Alphonsus Liew MBBS ,&nbsp;Sandra Howell MBBS ,&nbsp;Christopher Aldo Rinaldi MD, FHRS","doi":"10.1016/j.hrthm.2025.08.047","DOIUrl":"10.1016/j.hrthm.2025.08.047","url":null,"abstract":"","PeriodicalId":12886,"journal":{"name":"Heart rhythm","volume":"23 1","pages":"Pages e103-e104"},"PeriodicalIF":5.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145064747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to the letter to the editor entitled “High-risk transvenous lead extraction can be safely performed in the electrophysiology laboratory”","authors":"Robert D. Schaller DO, FHRS ,&nbsp;Balaram Krishna Hanumanthu MD ,&nbsp;Francis E. Marchlinski MD, FHRS ,&nbsp;Marisa Cevasco MD ,&nbsp;Michael Acker MD ,&nbsp;Joshua M. Cooper MD, FHRS ,&nbsp;Mouhannad M. Sadek MD, FHRS","doi":"10.1016/j.hrthm.2025.09.011","DOIUrl":"10.1016/j.hrthm.2025.09.011","url":null,"abstract":"","PeriodicalId":12886,"journal":{"name":"Heart rhythm","volume":"23 1","pages":"Pages e104-e105"},"PeriodicalIF":5.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145064592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient-reported outcomes of deep sedation during pulsed field ablation for atrial fibrillation with a novel variable-loop catheter","authors":"Vanessa Sciacca MD ,&nbsp;Philipp Lucas MD ,&nbsp;Thomas Fink MD ,&nbsp;Angeliki Darma MD ,&nbsp;Denise Guckel MD ,&nbsp;Maxim Didenko MD ,&nbsp;Maximilian Mörsdorf MD ,&nbsp;Martin Braun MD ,&nbsp;Moneeb Khalaph MD ,&nbsp;Yuri Bocchini MD ,&nbsp;Nadica Trajkovska MD ,&nbsp;Karen Harutyunyan MD ,&nbsp;Philipp Sommer MD, FHRS ,&nbsp;Christian Sohns MD, FHRS","doi":"10.1016/j.hrthm.2025.09.033","DOIUrl":"10.1016/j.hrthm.2025.09.033","url":null,"abstract":"","PeriodicalId":12886,"journal":{"name":"Heart rhythm","volume":"23 1","pages":"Pages e96-e98"},"PeriodicalIF":5.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":12886,"journal":{"name":"Heart rhythm","volume":"23 3","pages":"Pages e348-e356"},"PeriodicalIF":5.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147274562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":12886,"journal":{"name":"Heart rhythm","volume":"23 3","pages":"Pages 623-631"},"PeriodicalIF":5.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147274676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":12886,"journal":{"name":"Heart rhythm","volume":"23 3","pages":"Pages 665-670"},"PeriodicalIF":5.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147274681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":12886,"journal":{"name":"Heart rhythm","volume":"23 3","pages":"Pages e384-e391"},"PeriodicalIF":5.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147274673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}