Pub Date : 2025-09-01Epub Date: 2025-08-26DOI: 10.1177/11207000251362135
Jonathan Liu, Mohammad Daher, Noah Gilreath, Jared Sain, Nathaniel Smith, Matthew Quinn, Stephen Kayiaros, Valentin Antoci, Eric M Cohen
Introduction: Isolated femoral head and polyethylene liner exchange is commonly performed with varying surgical approaches used for the primary THA (pTHA) and the revision THA (rTHA). The purpose of this study is to investigate the prevalence and postoperative outcomes associated with concordance and discordance in isolated head-liner exchange.
Methods: A retrospective chart review from May 2016 to November 2023 was performed for all patients at 2 institutions who underwent isolated head-liner exchange. 175 patients had minimum 1-year follow-up with complete information regarding surgical approach and outcomes. 175 included were grouped based on their pTHA approach including posterior approach (PA), anterolateral (AL), and direct anterior (DA), and their subsequent rTHA approach. Demographics and postoperative outcomes were compared between groups. Chi-square tests were used to measure associations between surgical approaches and postoperative complications, with a p-value of <0.05 signifying statistical significance.
Results: Our study included 175 patients with isolated head-liner exchange, with a mean age of 68.5 ± 10.4 years. Of the 175 patients, 100 (57.1%) received primary THA via the posterior approach (PA), with 68.0% having concordant revisions. For the anterolateral (AL) and direct anterior (DA) primary approaches, 91.1% and 94.7% of revisions were concordant, respectively. Indication for revision differed by approach, particularly within the PA group, where instability favoured concordant revisions, and metallosis favoured discordant revisions. There was no significant difference in perioperative outcomes between concordant and discordant approaches, except the concordant group had more EBL, higher rates of transfusions, reoperations, and discharge to skilled nursing facilities (SNF).
Conclusions: In pTHA cohort, patients with PA approach were more likely to undergo head-liner exchange with a discordant approach via DA or AL. As no significant associations were found in any combination of discordant approaches with postoperative complications, surgeons should choose their head-liner approach without significant concern for discordance.
{"title":"Impact of primary surgical approach on revision approach for isolated head-liner exchange in total hip arthroplasty.","authors":"Jonathan Liu, Mohammad Daher, Noah Gilreath, Jared Sain, Nathaniel Smith, Matthew Quinn, Stephen Kayiaros, Valentin Antoci, Eric M Cohen","doi":"10.1177/11207000251362135","DOIUrl":"10.1177/11207000251362135","url":null,"abstract":"<p><strong>Introduction: </strong>Isolated femoral head and polyethylene liner exchange is commonly performed with varying surgical approaches used for the primary THA (pTHA) and the revision THA (rTHA). The purpose of this study is to investigate the prevalence and postoperative outcomes associated with concordance and discordance in isolated head-liner exchange.</p><p><strong>Methods: </strong>A retrospective chart review from May 2016 to November 2023 was performed for all patients at 2 institutions who underwent isolated head-liner exchange. 175 patients had minimum 1-year follow-up with complete information regarding surgical approach and outcomes. 175 included were grouped based on their pTHA approach including posterior approach (PA), anterolateral (AL), and direct anterior (DA), and their subsequent rTHA approach. Demographics and postoperative outcomes were compared between groups. Chi-square tests were used to measure associations between surgical approaches and postoperative complications, with a <i>p</i>-value of <0.05 signifying statistical significance.</p><p><strong>Results: </strong>Our study included 175 patients with isolated head-liner exchange, with a mean age of 68.5 ± 10.4 years. Of the 175 patients, 100 (57.1%) received primary THA via the posterior approach (PA), with 68.0% having concordant revisions. For the anterolateral (AL) and direct anterior (DA) primary approaches, 91.1% and 94.7% of revisions were concordant, respectively. Indication for revision differed by approach, particularly within the PA group, where instability favoured concordant revisions, and metallosis favoured discordant revisions. There was no significant difference in perioperative outcomes between concordant and discordant approaches, except the concordant group had more EBL, higher rates of transfusions, reoperations, and discharge to skilled nursing facilities (SNF).</p><p><strong>Conclusions: </strong>In pTHA cohort, patients with PA approach were more likely to undergo head-liner exchange with a discordant approach via DA or AL. As no significant associations were found in any combination of discordant approaches with postoperative complications, surgeons should choose their head-liner approach without significant concern for discordance.</p>","PeriodicalId":12911,"journal":{"name":"HIP International","volume":" ","pages":"517-522"},"PeriodicalIF":1.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144951789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-01Epub Date: 2024-10-07DOI: 10.1177/11207000241282398
Rashid M Tikhilov, Nikolai N Efimov, Igor I Shubnyakov, Maksim Y Goncharov, Dmitrii V Stafeev, Vitalii V Karelkin
Background: Constrained liners (CLs) have been used in revision total hip arthroplasty (rTHA) with varying results. Relatively few studies have identified specific risk factors for failure. This study aimed to assess implant survivorship and complication rates, identify risk factors for constraint-related complications, and assess the effect of multiple factors present in a single case.
Methods: We conducted a retrospective analysis of 101 rTHAs for various aseptic indications and as second-stage procedures for periprosthetic joint infection (PJI) utilising 2 models of conventional single-articulation CLs. We excluded 8 cases in which the liners were removed early due to PJI and assessed the risk factors for constraint-related complications in the remaining 93 cases. The mean follow-up duration for complication-free cases was 6.5 years (range 4.7-10.5 years).
Results: The incidences of dislocation of a prosthetic head and loosening of the acetabular component were 19.8% and 5.0%, respectively. We also observed 8 cases where the locking ring of the liner was dislodged without dislocation (1 case required re-revision). The presence of factors related to impingement (cup retention, smaller internal diameter CLs, signs of probable impingement from the femoral side) was associated with higher rates of constraint-related complications. The presence of factors related to soft-tissue stabilisers did not increase the rate of complications. The simultaneous presence of multiple impingement-related risk factors resulted in worse outcomes.
Conclusions: CLs may be less effective for treating or preventing instability related to impingement. CLs should be used with caution or avoided when multiple impingement-related risk factors are present.
{"title":"Conventional single articulation constrained liners in revision hip arthroplasty: risk factors for failure and their combinations.","authors":"Rashid M Tikhilov, Nikolai N Efimov, Igor I Shubnyakov, Maksim Y Goncharov, Dmitrii V Stafeev, Vitalii V Karelkin","doi":"10.1177/11207000241282398","DOIUrl":"10.1177/11207000241282398","url":null,"abstract":"<p><strong>Background: </strong>Constrained liners (CLs) have been used in revision total hip arthroplasty (rTHA) with varying results. Relatively few studies have identified specific risk factors for failure. This study aimed to assess implant survivorship and complication rates, identify risk factors for constraint-related complications, and assess the effect of multiple factors present in a single case.</p><p><strong>Methods: </strong>We conducted a retrospective analysis of 101 rTHAs for various aseptic indications and as second-stage procedures for periprosthetic joint infection (PJI) utilising 2 models of conventional single-articulation CLs. We excluded 8 cases in which the liners were removed early due to PJI and assessed the risk factors for constraint-related complications in the remaining 93 cases. The mean follow-up duration for complication-free cases was 6.5 years (range 4.7-10.5 years).</p><p><strong>Results: </strong>The incidences of dislocation of a prosthetic head and loosening of the acetabular component were 19.8% and 5.0%, respectively. We also observed 8 cases where the locking ring of the liner was dislodged without dislocation (1 case required re-revision). The presence of factors related to impingement (cup retention, smaller internal diameter CLs, signs of probable impingement from the femoral side) was associated with higher rates of constraint-related complications. The presence of factors related to soft-tissue stabilisers did not increase the rate of complications. The simultaneous presence of multiple impingement-related risk factors resulted in worse outcomes.</p><p><strong>Conclusions: </strong>CLs may be less effective for treating or preventing instability related to impingement. CLs should be used with caution or avoided when multiple impingement-related risk factors are present.</p>","PeriodicalId":12911,"journal":{"name":"HIP International","volume":" ","pages":"437-444"},"PeriodicalIF":1.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142380689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-18DOI: 10.1177/11207000251362177
Thomas Stark, Karl Stoffel, Thomas Ilchmann, Brigitta Gahl, Lukas Zwicky, Peter E Ochsner, Martin Clauss
Background: Although the Burch-Schneider antiprotrusio cage (BS-APC) has been reported to be reliable, long-term data for this implant are scarce. We thus aimed to investigate survival and radiological results for revision total hip arthroplasty with the BS-APC in patients with major bone deficiency (55% AAOS defect grade 3, 39% grade 4) who had a minimum follow-up of 5 years (mean 10.2 years).
Methods: 144 revisions in 140 patients were performed due to aseptic loosening (n= 74), infection (n = 50), or other reasons (n = 20). Survival analysis was performed with death as a competing risk. Clinical follow-up was performed at 1, 2, and 5 years and every 5 years thereafter.
Results: 77 patients died during follow-up, 25 within the first 5 years. 12 BS-APCs were re-revised for infection (n = 5), aseptic loosening (n = 5), or instability (n = 2). The cumulative incidence for aseptic re-revision of BS-APCs was 4.3% at 10 years (95% CI, 1.8-10.1%), and the cumulative risk of death was 73.3% (95% CI, 62.4-83.2%). Radiological changes occurred in 26 of 87 radiologically examined hips, of which 8 cases were revised.
Conclusions: We found excellent mid- and long-term survival of the BS-APC in acetabular revision with major bone deficiencies, in accordance with or superior to most literature reports, which might be explained by strict adherence to surgical technique.
{"title":"Long-term results of the Burch-Schneider antiprotrusio cage: a single-centre follow-up of 144 cases after a minimum of 5 years.","authors":"Thomas Stark, Karl Stoffel, Thomas Ilchmann, Brigitta Gahl, Lukas Zwicky, Peter E Ochsner, Martin Clauss","doi":"10.1177/11207000251362177","DOIUrl":"https://doi.org/10.1177/11207000251362177","url":null,"abstract":"<p><strong>Background: </strong>Although the Burch-Schneider antiprotrusio cage (BS-APC) has been reported to be reliable, long-term data for this implant are scarce. We thus aimed to investigate survival and radiological results for revision total hip arthroplasty with the BS-APC in patients with major bone deficiency (55% AAOS defect grade 3, 39% grade 4) who had a minimum follow-up of 5 years (mean 10.2 years).</p><p><strong>Methods: </strong>144 revisions in 140 patients were performed due to aseptic loosening (<i>n</i> <i>=</i> 74), infection (<i>n</i> = 50), or other reasons (<i>n</i> = 20). Survival analysis was performed with death as a competing risk. Clinical follow-up was performed at 1, 2, and 5 years and every 5 years thereafter.</p><p><strong>Results: </strong>77 patients died during follow-up, 25 within the first 5 years. 12 BS-APCs were re-revised for infection (<i>n</i> = 5), aseptic loosening (<i>n</i> = 5), or instability (<i>n</i> = 2). The cumulative incidence for aseptic re-revision of BS-APCs was 4.3% at 10 years (95% CI, 1.8-10.1%), and the cumulative risk of death was 73.3% (95% CI, 62.4-83.2%). Radiological changes occurred in 26 of 87 radiologically examined hips, of which 8 cases were revised.</p><p><strong>Conclusions: </strong>We found excellent mid- and long-term survival of the BS-APC in acetabular revision with major bone deficiencies, in accordance with or superior to most literature reports, which might be explained by strict adherence to surgical technique.</p>","PeriodicalId":12911,"journal":{"name":"HIP International","volume":" ","pages":"11207000251362177"},"PeriodicalIF":1.1,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144872882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-18DOI: 10.1177/11207000251365201
Roderick J M Vossen, Gaby V Ten Noever de Brauw, Jore H Willems, Rienk Eshuis, Inger N Sierevelt, Anneke Spekenbrink-Spooren, Hendrik A Zuiderbaan
Background: The association between primary total hip arthroplasty (THA) approaches and short-term mortality rates remained unexplored. This study aimed to compare short-term mortality rates between the direct anterior (DAA), posterolateral (PL), anterolateral (AL) and direct lateral (DL) approaches and determine associated factors.
Methods: A registry study was conducted using data from 2007 to 2023 of the Dutch Arthroplasty Register. 30- and 90-day mortality were compared between approaches using the chi-square test and the logistic regression analysis to adjust for confounders (age, sex, patient's physical status [ASA] classification, fixation method, body mass index [BMI] and smoking status). Multivariate regression models were used to determine factors associated with short-term mortality. Sensitivity analyses for time periods (2007-2012, 2013-2017, 2018-2023) were performed.
Results: The study comprised 379,108 patients (mean age 69.9 ± 9.5, male 33.8%). The AL, PL and DL approaches demonstrated a significantly larger likelihood for 30-day mortality compared to the DAA after adjusting for confounders (DAA: reference; AL: OR 2.32 [1.52-3.57], p < 0.001; PL: OR 1.79 [1.36-2.36], p < 0.001; DL: OR 2.78 [1.69-4.57], p < 0 .001). In ASA I-II patients, likelihood for 90-day mortality for the AL, PL and DL approaches was significantly higher than the DAA approach (DAA: reference; AL: OR 2.293, p < 0.001; PL: OR 1.963, p < 0.001; DL: OR 2.016, p < 0.001). In ASA III-IV patients, differences were not significant, except when comparing the DL to the DAA approach (OR 1.484, p = 0.011). Increased age, male sex, surgical approach and cemented fixation were significantly associated with 30- and 90-day mortality.
Conclusions: Findings were suggestive that the DAA provides a reduced likelihood for short-term mortality compared to the PL, AL and DL, after adjusting for confounding factors. Differences in mortality rate were more substantial in healthy patients and remained similar irrespective of time periods. Increased age, male sex, surgical approach, and cemented fixation increased likelihood on short-term mortality.
背景:原发性全髋关节置换术(THA)入路与短期死亡率之间的关系尚不清楚。本研究旨在比较直接前路(DAA)、后外侧(PL)、前外侧(AL)和直接外侧(DL)入路的短期死亡率,并确定相关因素。方法:采用2007年至2023年荷兰关节成形术登记的数据进行登记研究,采用卡方检验和logistic回归分析比较两种方法的30天和90天死亡率,以调整混杂因素(年龄、性别、患者身体状况[ASA]分类、固定方法、体重指数[BMI]和吸烟状况)。采用多元回归模型确定与短期死亡率相关的因素。对时间段(2007-2012年、2013-2017年、2018-2023年)进行敏感性分析。结果:共纳入379108例患者,平均年龄69.9±9.5岁,男性33.8%。调整混杂因素后,AL、PL和DL方法与DAA方法相比,显示出显著更高的30天死亡率(DAA:参考;AL: OR 2.32 [1.52-3.57], pp pp pp = 0.011)。年龄、男性、手术入路和骨水泥固定与30天和90天死亡率显著相关。结论:研究结果提示,在调整混杂因素后,与PL、AL和DL相比,DAA提供了降低短期死亡率的可能性。健康患者的死亡率差异更大,并且在任何时期都保持相似。年龄、男性、手术入路和骨水泥固定增加了短期死亡率的可能性。
{"title":"The direct anterior approach in total hip arthroplasty may be associated with lower short-term mortality compared to various other approaches: a Dutch arthroplasty register study comprising 379,108 procedures.","authors":"Roderick J M Vossen, Gaby V Ten Noever de Brauw, Jore H Willems, Rienk Eshuis, Inger N Sierevelt, Anneke Spekenbrink-Spooren, Hendrik A Zuiderbaan","doi":"10.1177/11207000251365201","DOIUrl":"10.1177/11207000251365201","url":null,"abstract":"<p><strong>Background: </strong>The association between primary total hip arthroplasty (THA) approaches and short-term mortality rates remained unexplored. This study aimed to compare short-term mortality rates between the direct anterior (DAA), posterolateral (PL), anterolateral (AL) and direct lateral (DL) approaches and determine associated factors.</p><p><strong>Methods: </strong>A registry study was conducted using data from 2007 to 2023 of the Dutch Arthroplasty Register. 30- and 90-day mortality were compared between approaches using the chi-square test and the logistic regression analysis to adjust for confounders (age, sex, patient's physical status [ASA] classification, fixation method, body mass index [BMI] and smoking status). Multivariate regression models were used to determine factors associated with short-term mortality. Sensitivity analyses for time periods (2007-2012, 2013-2017, 2018-2023) were performed.</p><p><strong>Results: </strong>The study comprised 379,108 patients (mean age 69.9 ± 9.5, male 33.8%). The AL, PL and DL approaches demonstrated a significantly larger likelihood for 30-day mortality compared to the DAA after adjusting for confounders (DAA: reference; AL: OR 2.32 [1.52-3.57], <i>p</i> < 0.001; PL: OR 1.79 [1.36-2.36], <i>p</i> < 0.001; DL: OR 2.78 [1.69-4.57], <i>p</i> < 0 .001). In ASA I-II patients, likelihood for 90-day mortality for the AL, PL and DL approaches was significantly higher than the DAA approach (DAA: reference; AL: OR 2.293, <i>p</i> < 0.001; PL: OR 1.963, <i>p</i> < 0.001; DL: OR 2.016, <i>p</i> < 0.001). In ASA III-IV patients, differences were not significant, except when comparing the DL to the DAA approach (OR 1.484, <i>p</i> = 0.011). Increased age, male sex, surgical approach and cemented fixation were significantly associated with 30- and 90-day mortality.</p><p><strong>Conclusions: </strong>Findings were suggestive that the DAA provides a reduced likelihood for short-term mortality compared to the PL, AL and DL, after adjusting for confounding factors. Differences in mortality rate were more substantial in healthy patients and remained similar irrespective of time periods. Increased age, male sex, surgical approach, and cemented fixation increased likelihood on short-term mortality.</p>","PeriodicalId":12911,"journal":{"name":"HIP International","volume":" ","pages":"11207000251365201"},"PeriodicalIF":1.1,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144872883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-18DOI: 10.1177/11207000251364214
Itay Ashkenazi, Weston Buehring, Armin Arshi, Vinay K Aggarwal, Joseph A Bosco, Ran Schwarzkopf
Background: 10 years after changing our institution's total hip arthroplasty (THA) preoperative antibiotic prophylactic protocol by adding gram-negative (GN) coverage, this study aimed to assess the impact of adding GN specific coverage (GNSC) prior to THA on periprosthetic joint infection (PJI) rates.
Methods: This was a retrospective case-control study of 14,598 patients who underwent primary, elective THA between July 2012 and January 2022, with minimum 1-year follow-up. All patients were under perioperative antibiotic protocol that included GNSC with either weight-based gentamicin or aztreonam (+GNSC) and were compared to a historical control group of patients for which the antibiotic prophylactic protocol did not include GNSC (-GNSC). PJI and nephrotoxicity rates, as well as the severity of nephrotoxicity according to the RIFLE criteria, were compared between the study populations and 4122 controls.
Results: Proportions of GN-related PJIs among culture-positive (13.70 vs. 26.53%, p = 0.076) and all PJIs (10.64 vs. 26.53%, p = 0.014) were lower for +GNSC patients, while the proportion of PJIs caused by a gram-positive bacteria were similar between groups (87.67 vs. 83.67%, p = 0.532). While the +GNSC group have significantly higher rates of nephrotoxicity (2.87 vs. 1.78%, p = 0.003), the rates of kidney injury (0.39 vs. 0.39%, p = 0.998) and kidney failure (0.17 vs. 0.16%, p = 0.567), which are the two more severe forms of nephrotoxicity, were comparable between the groups.
Conclusions: The addition of gentamicin or aztreonam prior to THA reduces the incidence of GN-related PJIs. Increased nephrotoxicity rates were limited to the mildest form, usually associated with reversibility and favourable outcomes.
背景:在通过增加革兰氏阴性(GN)覆盖改变我院全髋关节置换术(THA)术前抗生素预防方案10年后,本研究旨在评估在THA前增加革兰氏阴性(GN)特异性覆盖(GNSC)对假体周围关节感染(PJI)率的影响。方法:这是一项回顾性病例对照研究,对2012年7月至2022年1月期间接受原发性选择性THA的14,598例患者进行了至少1年的随访。所有患者均接受围手术期抗生素治疗方案,包括GNSC与基于体重的庆大霉素或氨曲南(+GNSC),并与历史对照组进行比较,对照组的抗生素预防方案不包括GNSC (-GNSC)。比较研究人群和4122名对照者的PJI和肾毒性率,以及根据RIFLE标准的肾毒性严重程度。结果:培养阳性(13.70 vs. 26.53%, p = 0.076)和阴性(10.64 vs. 26.53%, p = 0.014)患者gn相关PJIs比例较低,而革兰氏阳性菌引起的PJIs比例组间比较相似(87.67 vs. 83.67%, p = 0.532)。虽然+GNSC组肾毒性发生率明显较高(2.87比1.78%,p = 0.003),但肾损伤(0.39比0.39%,p = 0.998)和肾衰竭(0.17比0.16%,p = 0.567)这两种更严重的肾毒性发生率在两组之间具有可比性。结论:THA术前加用庆大霉素或氨曲南可降低gn相关PJIs的发生率。增加的肾毒性率仅限于最轻微的形式,通常与可逆性和有利的结果有关。
{"title":"The sustained benefits of gram-negative antimicrobial prophylaxis in total hip arthroplasty: a 10-year retrospective analysis.","authors":"Itay Ashkenazi, Weston Buehring, Armin Arshi, Vinay K Aggarwal, Joseph A Bosco, Ran Schwarzkopf","doi":"10.1177/11207000251364214","DOIUrl":"https://doi.org/10.1177/11207000251364214","url":null,"abstract":"<p><strong>Background: </strong>10 years after changing our institution's total hip arthroplasty (THA) preoperative antibiotic prophylactic protocol by adding gram-negative (GN) coverage, this study aimed to assess the impact of adding GN specific coverage (GNSC) prior to THA on periprosthetic joint infection (PJI) rates.</p><p><strong>Methods: </strong>This was a retrospective case-control study of 14,598 patients who underwent primary, elective THA between July 2012 and January 2022, with minimum 1-year follow-up. All patients were under perioperative antibiotic protocol that included GNSC with either weight-based gentamicin or aztreonam (+GNSC) and were compared to a historical control group of patients for which the antibiotic prophylactic protocol did not include GNSC (-GNSC). PJI and nephrotoxicity rates, as well as the severity of nephrotoxicity according to the RIFLE criteria, were compared between the study populations and 4122 controls.</p><p><strong>Results: </strong>Proportions of GN-related PJIs among culture-positive (13.70 vs. 26.53%, <i>p</i> = 0.076) and all PJIs (10.64 vs. 26.53%, <i>p</i> = 0.014) were lower for +GNSC patients, while the proportion of PJIs caused by a gram-positive bacteria were similar between groups (87.67 vs. 83.67%, <i>p</i> = 0.532). While the +GNSC group have significantly higher rates of nephrotoxicity (2.87 vs. 1.78%, <i>p</i> = 0.003), the rates of kidney injury (0.39 vs. 0.39%, <i>p</i> = 0.998) and kidney failure (0.17 vs. 0.16%, <i>p</i> = 0.567), which are the two more severe forms of nephrotoxicity, were comparable between the groups.</p><p><strong>Conclusions: </strong>The addition of gentamicin or aztreonam prior to THA reduces the incidence of GN-related PJIs. Increased nephrotoxicity rates were limited to the mildest form, usually associated with reversibility and favourable outcomes.</p>","PeriodicalId":12911,"journal":{"name":"HIP International","volume":" ","pages":"11207000251364214"},"PeriodicalIF":1.1,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144872884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-01Epub Date: 2020-07-07DOI: 10.1177/1120700020939075
Wouter H Mallee, Anne E Wijsbek, Matthias U Schafroth, Julius Wolkenfelt, Dominique C Baas, Ton M J S Vervest
Objective: Does the use of staples or sutures for wound closure have a lower surgical site infection rate in patients receiving primary total hip arthroplasty (THA)?
Methods: 535 patients undergoing THA were included and randomised into 2 groups: 268 wounds were closed with staples, and 267 with sutures. Primary outcome was surgical site infection (SSI). Secondary outcomes were prosthetic joint infection (PJI), other wound complications (dehiscence, necrosis and prolonged drainage) and duration of admittance. Follow-up occurred at 2, 6, and 12 weeks, and at 1 year.
Results: There were no significant demographic differences between the 2 groups. SSI occurred more frequently when wounds were closed with staples (4% compared to 1% with sutures; OR 2.8; CI, 0.885-0.952; p = 0.057). SSI was treated with oral antibiotics. The staples group showed significantly more wound complications (17% compared to 5%; OR 3.943, CI 2.073-7.498; p = 0.000). Wound discharge was significantly prolonged in the staples group (n = 40, compared to n = 12 in the sutures group; OR 3.728; CI, 1.909-7.281; p = 0.000). There was no significant difference in PJI (p = 0.364).
Conclusions: In this large RCT comparing staples with sutures after THA, the use of staples is associated with a nearly 3 times greater risk of SSI (OR 2.8; p = 0.057). Staples significantly prolong wound discharge. The use of sutures for wound closure after THA is advised.Trial registration: Staples Or Sutures trial (S.O.S. trial) http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=3946, NTR3946.
{"title":"Wound complications after total hip arthroplasty: a prospective, randomised controlled trial comparing staples with sutures.","authors":"Wouter H Mallee, Anne E Wijsbek, Matthias U Schafroth, Julius Wolkenfelt, Dominique C Baas, Ton M J S Vervest","doi":"10.1177/1120700020939075","DOIUrl":"10.1177/1120700020939075","url":null,"abstract":"<p><strong>Objective: </strong>Does the use of staples or sutures for wound closure have a lower surgical site infection rate in patients receiving primary total hip arthroplasty (THA)?</p><p><strong>Design: </strong>Prospective, randomised controlled multicentre trial.</p><p><strong>Methods: </strong>535 patients undergoing THA were included and randomised into 2 groups: 268 wounds were closed with staples, and 267 with sutures. Primary outcome was surgical site infection (SSI). Secondary outcomes were prosthetic joint infection (PJI), other wound complications (dehiscence, necrosis and prolonged drainage) and duration of admittance. Follow-up occurred at 2, 6, and 12 weeks, and at 1 year.</p><p><strong>Results: </strong>There were no significant demographic differences between the 2 groups. SSI occurred more frequently when wounds were closed with staples (4% compared to 1% with sutures; OR 2.8; CI, 0.885-0.952; <i>p</i> = 0.057). SSI was treated with oral antibiotics. The staples group showed significantly more wound complications (17% compared to 5%; OR 3.943, CI 2.073-7.498; <i>p</i> = 0.000). Wound discharge was significantly prolonged in the staples group (<i>n</i> = 40, compared to <i>n</i> = 12 in the sutures group; OR 3.728; CI, 1.909-7.281; <i>p</i> = 0.000). There was no significant difference in PJI (<i>p</i> = 0.364).</p><p><strong>Conclusions: </strong>In this large RCT comparing staples with sutures after THA, the use of staples is associated with a nearly 3 times greater risk of SSI (OR 2.8; <i>p</i> = 0.057). Staples significantly prolong wound discharge. The use of sutures for wound closure after THA is advised.<b>Trial registration:</b> Staples Or Sutures trial (S.O.S. trial) http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=3946, NTR3946.</p>","PeriodicalId":12911,"journal":{"name":"HIP International","volume":" ","pages":"326-331"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38132910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-01Epub Date: 2025-06-08DOI: 10.1177/11207000251345995
James E Miller, Ibrahim Inzarul Haq, Elizabeth Hedge, Paul Saunders, Muhamed M Farhan-Alanie, Siew Wan Hee, Ajay Chourasia, Prasad Rao, Steve K Young
Background: The presence of radiolucent lines (RLLs) around total hip replacement (THR) stems correlates with stem failure. However, the zone this occurs in is significant. The widely adopted Gruen Zone classification has disadvantages and is unlikely to be reflective of uncemented biomechanics. We propose a simpler system for describing these changes and introduce its relevance clinically.
Methods: In a single-centre retrospective study CORAIL THR stems implanted between 2010 and 2013 were analysed. On postoperative radiographs 2 parallel "SKY" lines divided the stem bone interface into 3 zones A, B and C. 1 year and 5 years postoperative radiographs were reviewed by 5 surgeons for the presence and location of RLLs. The revision rates of the UK's National Joint Registry were correlated with the presence of RLLs.
Results: 1113 stems were included.331 (29.7%) had RLLs, 273 (24.5%) in zone A only, 50 (4.5%) in zones A and B and 8 (0.7%) in all 3 zones A, B and C. In absence of RRLs in zone A, no RLLs were identified in the other zones. 73% RRLs appeared in the first postoperative year, the remaining at 5 years follow-up.1.8% (20 of 1113) stems were revised. The revision rate for stems with RLLs in zone A alone was 2.9%, with RLLs in zone A and B it was 12% and with RLLs in all 3 zones it was 12.5%.The odds of revision were 4.7 times higher (p = 0.007) with RLLs in Zone A and 6.6 times higher (p < 0.001) with RLLs in Zones B and C compared to those without.
Conclusions: The SKY lines can be used to classify RLLs and predict the risk of revision for the CORAIL stem. Stems with RLLs progressing beyond the first SKY line from zone A into Zone B-C should be considered higher risk for revision and hence followed-up closely for signs of failure. Absence of RLLs or RLLs in Zone A only can be discharged to patient-initiated follow-up.
{"title":"The SKY is the limit - a novel system for interpreting radiolucent lines around CORAIL uncemented total hip arthroplasty stems: a proof-of-concept study.","authors":"James E Miller, Ibrahim Inzarul Haq, Elizabeth Hedge, Paul Saunders, Muhamed M Farhan-Alanie, Siew Wan Hee, Ajay Chourasia, Prasad Rao, Steve K Young","doi":"10.1177/11207000251345995","DOIUrl":"10.1177/11207000251345995","url":null,"abstract":"<p><strong>Background: </strong>The presence of radiolucent lines (RLLs) around total hip replacement (THR) stems correlates with stem failure. However, the zone this occurs in is significant. The widely adopted Gruen Zone classification has disadvantages and is unlikely to be reflective of uncemented biomechanics. We propose a simpler system for describing these changes and introduce its relevance clinically.</p><p><strong>Methods: </strong>In a single-centre retrospective study CORAIL THR stems implanted between 2010 and 2013 were analysed. On postoperative radiographs 2 parallel \"SKY\" lines divided the stem bone interface into 3 zones A, B and C. 1 year and 5 years postoperative radiographs were reviewed by 5 surgeons for the presence and location of RLLs. The revision rates of the UK's National Joint Registry were correlated with the presence of RLLs.</p><p><strong>Results: </strong>1113 stems were included.331 (29.7%) had RLLs, 273 (24.5%) in zone A only, 50 (4.5%) in zones A and B and 8 (0.7%) in all 3 zones A, B and C. In absence of RRLs in zone A, no RLLs were identified in the other zones. 73% RRLs appeared in the first postoperative year, the remaining at 5 years follow-up.1.8% (20 of 1113) stems were revised. The revision rate for stems with RLLs in zone A alone was 2.9%, with RLLs in zone A and B it was 12% and with RLLs in all 3 zones it was 12.5%.The odds of revision were 4.7 times higher (<i>p =</i> 0.007) with RLLs in Zone A and 6.6 times higher (<i>p <</i> 0.001) with RLLs in Zones B and C compared to those without.</p><p><strong>Conclusions: </strong>The SKY lines can be used to classify RLLs and predict the risk of revision for the CORAIL stem. Stems with RLLs progressing beyond the first SKY line from zone A into Zone B-C should be considered higher risk for revision and hence followed-up closely for signs of failure. Absence of RLLs or RLLs in Zone A only can be discharged to patient-initiated follow-up.</p>","PeriodicalId":12911,"journal":{"name":"HIP International","volume":" ","pages":"344-352"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144247548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Purpose: Studies on short-stem total hip arthroplasty (THA) in young patients with developmental dysplasia of the hip (DDH) are limited, with no studies on long-term outcomes. Our study aimed to investigate whether the Mayo conservative hip stem demonstrates favourable mid- to long-term outcomes in these patients.
Methods: This retrospective study included 42 patients (50 joints) with DDH aged <55 years who underwent THA using the Mayo conservative hip stem and excluded those with a follow-up period <5 years. Radiographic evaluation involved comparison of the immediate postoperative anteroposterior images with those at the final follow-up. Clinical evaluations utilised the Japanese Orthopaedic Association (JOA) hip score and major postoperative complications, including revision surgery.
Results: The mean age of the patients was 48.8 years, with a median follow-up of 11 years. According to the Crowe classification, 35, 11, and 4 cases were classified as Types I, II, and III, respectively. According to the Dorr classification, 29 and 21 cases were classified as Types A and B, respectively. Radiographically, spot welds were observed in 98% of joints in zones 2 or 6, whereas stress shielding was evident in 94% (zone 1) and 54% (zone 7) of the joints. Stem sinking ⩾3 mm was observed in 2 joints. No periprosthetic femoral fractures, dislocations, or infections were observed.
Conclusions: The Mayo conservative stem in young patients with DDH resulted in favourable mid- to long-term outcomes, including stability and bone preservation. The stem is an effective treatment strategy for these patients.
{"title":"Mayo conservative hip stem for proximal femoral bone preservation in developmental dysplasia of the hip in young patients: a median follow-up of more than 10 years.","authors":"Masanori Nishi, Takashi Atsumi, Yasushi Yoshikawa, Ryosuke Nakanishi, Minoru Watanabe, Tsubasa Ishikawa, Yuki Usui, Tokito Tatsuo, Yoshifumi Kudo","doi":"10.1177/11207000251338196","DOIUrl":"10.1177/11207000251338196","url":null,"abstract":"<p><strong>Purpose: </strong>Studies on short-stem total hip arthroplasty (THA) in young patients with developmental dysplasia of the hip (DDH) are limited, with no studies on long-term outcomes. Our study aimed to investigate whether the Mayo conservative hip stem demonstrates favourable mid- to long-term outcomes in these patients.</p><p><strong>Methods: </strong>This retrospective study included 42 patients (50 joints) with DDH aged <55 years who underwent THA using the Mayo conservative hip stem and excluded those with a follow-up period <5 years. Radiographic evaluation involved comparison of the immediate postoperative anteroposterior images with those at the final follow-up. Clinical evaluations utilised the Japanese Orthopaedic Association (JOA) hip score and major postoperative complications, including revision surgery.</p><p><strong>Results: </strong>The mean age of the patients was 48.8 years, with a median follow-up of 11 years. According to the Crowe classification, 35, 11, and 4 cases were classified as Types I, II, and III, respectively. According to the Dorr classification, 29 and 21 cases were classified as Types A and B, respectively. Radiographically, spot welds were observed in 98% of joints in zones 2 or 6, whereas stress shielding was evident in 94% (zone 1) and 54% (zone 7) of the joints. Stem sinking ⩾3 mm was observed in 2 joints. No periprosthetic femoral fractures, dislocations, or infections were observed.</p><p><strong>Conclusions: </strong>The Mayo conservative stem in young patients with DDH resulted in favourable mid- to long-term outcomes, including stability and bone preservation. The stem is an effective treatment strategy for these patients.</p>","PeriodicalId":12911,"journal":{"name":"HIP International","volume":" ","pages":"377-383"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144077437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-01Epub Date: 2025-05-15DOI: 10.1177/11207000251337403
Seth Spicer, Hanna Brancaccio, Ashley Sundin, Jamie Bono, John DesRochers, Brandon Goodwin, Nicholas Averell, Seungkyu Park, Alexandra Goodwin, William DiCiurcio, Richard Jermyn
Background: The objective of this study was to determine the effect of bone marrow aspirate concentrate (BMAC) on long-term patient outcomes when used as an adjuvant to acetabular repair of the labrum.
Methods: A systematic review and meta-analysis were completed following PRISMA 2020 guidelines. Included in the analysis were controlled studies which assessed functional outcomes via the International Hip Outcome Tool-33 (iHOT-33) 12 or 24 months after acetabular repair with BMAC adjunct. 4 studies totaling 315 participants were analysed.
Results: Pooled effect sizes for iHOT-33 scores were not significantly different between control and treatment groups at 12 (p= 0.14, Cohen's D ≏ 0.79) or 24 months (p= 0.30, Cohen's D ≏ 0.56).
Conclusions: Non-significant trends in favour of BMAC augmentation were found in this study. However, the trends reported are promising and warrant further investigation with further randomised controlled trials.
{"title":"Bone marrow aspirate concentrate adjunct for acetabular labral tear repair: a systematic review and meta-analysis.","authors":"Seth Spicer, Hanna Brancaccio, Ashley Sundin, Jamie Bono, John DesRochers, Brandon Goodwin, Nicholas Averell, Seungkyu Park, Alexandra Goodwin, William DiCiurcio, Richard Jermyn","doi":"10.1177/11207000251337403","DOIUrl":"10.1177/11207000251337403","url":null,"abstract":"<p><strong>Background: </strong>The objective of this study was to determine the effect of bone marrow aspirate concentrate (BMAC) on long-term patient outcomes when used as an adjuvant to acetabular repair of the labrum.</p><p><strong>Methods: </strong>A systematic review and meta-analysis were completed following PRISMA 2020 guidelines. Included in the analysis were controlled studies which assessed functional outcomes via the International Hip Outcome Tool-33 (iHOT-33) 12 or 24 months after acetabular repair with BMAC adjunct. 4 studies totaling 315 participants were analysed.</p><p><strong>Results: </strong>Pooled effect sizes for iHOT-33 scores were not significantly different between control and treatment groups at 12 (<i>p</i> <i>=</i> 0.14, Cohen's D ≏ 0.79) or 24 months (<i>p</i> <i>=</i> 0.30, Cohen's D ≏ 0.56).</p><p><strong>Conclusions: </strong>Non-significant trends in favour of BMAC augmentation were found in this study. However, the trends reported are promising and warrant further investigation with further randomised controlled trials.</p>","PeriodicalId":12911,"journal":{"name":"HIP International","volume":" ","pages":"392-401"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12198464/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144077433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-01Epub Date: 2025-05-04DOI: 10.1177/11207000251335223
Pablo A Slullitel, Marcos Latorre, Francisco Principe, Felipe Patterson, Gerardo Zanotti, Fernando Comba, Martin A Buttaro
Background: To report the association between os acetabuli and relevant radiologic measurements in a series of surgically treated hip preservation patients.
Methods: We retrospectively reviewed 654 hips who underwent preservation surgery between 2012 and 2019, identifying 50 cases with os acetabuli (7.64%). We included 300 hips (277 patients) with radiographs and CT-scans obtained during preoperative assessment, after which the cohort was divided into two groups (with and without os acetabuli). Mean age of the study population was 35 (interquartile range [IQR] 28-42) years old, with 192 (62%) being males. 2 observers measured demographic and radiologic variables. A mixed-effects logistic regression tested the ability of radiologic measurements to predict the presence of os acetabuli.
Results: No between-group differences were found in terms of sex (156/250 vs. 36/50 males, p = 0.197), alpha angle (64 ± 13° vs. 65 ± 14°, p = 0.372), Tönnis angle (8 ± 7° vs. 7 ± 7°, p = 0.152), neck-shaft angle (132 ± 6° vs. 131 ± 5°, p = 0.199) and CT-acetabular version (16 ± 7° vs. 15 ± 6°, p = 0.221). Significant differences were found in terms of age (34 ± 9 vs. 39 ± 7 years, p = 0.002), lateral centre-edge angle (LCEA) (31 ± 9° vs. 34 ± 7°, p = 0.045), anterior wall index (AWI) (0.45 [IQR 0.37-0.54] vs 0.5 [IQR 0.39-0.6], p = 0.046), CT-femoral version (17 ± 5° vs. 8 ± 4°, p < 0.001), cross-over sign (96/250 vs. 28/50, p = 0.032) and baseline diagnosis (184/250 vs. 44/50 FAIs, p = 0.043), with the os acetabuli-group being older, with more FAI diagnosis/cross-over sign, and with higher LCEA, higher AWI, and a lower femoral version. After adjusting for confounders, only CT-femoral version (odds ratio 0.32; 95% CI. 0.14-0.73, p < 0.007) was associated with presence of os acetabuli.
Conclusions: Presence of acetabular rim fragments was significantly associated with a lower femoral version. Above 20° of femoral version, the likelihood of os acetabuli was almost zero. Treatment of os acetabuli (i.e., fixation vs. removal) should be adjusted for the underlying diagnosis.
{"title":"Os acetabuli is an indirect radiographic sign of femoral retroversion.","authors":"Pablo A Slullitel, Marcos Latorre, Francisco Principe, Felipe Patterson, Gerardo Zanotti, Fernando Comba, Martin A Buttaro","doi":"10.1177/11207000251335223","DOIUrl":"10.1177/11207000251335223","url":null,"abstract":"<p><strong>Background: </strong>To report the association between os acetabuli and relevant radiologic measurements in a series of surgically treated hip preservation patients.</p><p><strong>Methods: </strong>We retrospectively reviewed 654 hips who underwent preservation surgery between 2012 and 2019, identifying 50 cases with os acetabuli (7.64%). We included 300 hips (277 patients) with radiographs and CT-scans obtained during preoperative assessment, after which the cohort was divided into two groups (with and without os acetabuli). Mean age of the study population was 35 (interquartile range [IQR] 28-42) years old, with 192 (62%) being males. 2 observers measured demographic and radiologic variables. A mixed-effects logistic regression tested the ability of radiologic measurements to predict the presence of os acetabuli.</p><p><strong>Results: </strong>No between-group differences were found in terms of sex (156/250 vs. 36/50 males, <i>p =</i> 0.197), alpha angle (64 ± 13° vs. 65 ± 14°, <i>p =</i> 0.372), Tönnis angle (8 ± 7° vs. 7 ± 7°, <i>p =</i> 0.152), neck-shaft angle (132 ± 6° vs. 131 ± 5°, <i>p =</i> 0.199) and CT-acetabular version (16 ± 7° vs. 15 ± 6°, <i>p =</i> 0.221). Significant differences were found in terms of age (34 ± 9 vs. 39 ± 7 years, <i>p =</i> 0.002), lateral centre-edge angle (LCEA) (31 ± 9° vs. 34 ± 7°, <i>p =</i> 0.045), anterior wall index (AWI) (0.45 [IQR 0.37-0.54] vs 0.5 [IQR 0.39-0.6], <i>p =</i> 0.046), CT-femoral version (17 ± 5° vs. 8 ± 4°, <i>p <</i> 0.001), cross-over sign (96/250 vs. 28/50, <i>p =</i> 0.032) and baseline diagnosis (184/250 vs. 44/50 FAIs, <i>p =</i> 0.043), with the os acetabuli-group being older, with more FAI diagnosis/cross-over sign, and with higher LCEA, higher AWI, and a lower femoral version. After adjusting for confounders, only CT-femoral version (odds ratio 0.32; 95% CI. 0.14-0.73, <i>p <</i> 0.007) was associated with presence of os acetabuli.</p><p><strong>Conclusions: </strong>Presence of acetabular rim fragments was significantly associated with a lower femoral version. Above 20° of femoral version, the likelihood of os acetabuli was almost zero. Treatment of os acetabuli (i.e., fixation vs. removal) should be adjusted for the underlying diagnosis.</p>","PeriodicalId":12911,"journal":{"name":"HIP International","volume":" ","pages":"384-391"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143984204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}