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Comparison of three-dimensional imaging of the nose using three different 3D-photography systems: an observational study. 使用三种不同 3D 摄影系统对鼻部进行三维成像的比较:一项观察研究。
IF 2.4 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-01-24 DOI: 10.1186/s13005-024-00406-4
Lucas M Ritschl, Carolina Classen, Paul Kilbertus, Julia Eufinger, Katharina Storck, Andreas M Fichter, Klaus-Dietrich Wolff, Florian D Grill

Background: New 3D technologies for superficial soft tissue changes, especially in plastic and reconstructive surgical procedures, can improve the planning and documentation of facial surgeries. The purpose of this study was to compare and determine the applicability and feasibility of three different 3D-photography systems in clinical practice imaging the nose.

Methods: A total of 16 healthy non-operated noses were included in this prospective study. A plaster model of each nose was produced, digitized, and converted to a .stl mesh (= ground truth model). Three-dimensional images of each nose were then taken using Artec Space Spider (gold standard), Planmeca ProFace®, and the Bellus3D Dental Pro application. All resulting .stl files were aligned to the ground truth model using MeshLab software, and the root mean square error (RMSE), mean surface distance (MSD), and Hausdorff distance (HD) were calculated.

Results: The Artec Space Spider 3D-photography system showed significantly better results compared to the two other systems in regard to RMSE, MSD, and HD (each p < 0.001). There was no significant difference between Planmeca ProFace® and Bellus3D Dental Pro in terms of RMSE, MSD, and HD. Overall, all three camera systems showed a clinically acceptable deviation to the reference model (range: -1.23-1.57 mm).

Conclusions: The three evaluated 3D-photography systems were suitable for nose imaging in the clinical routine. While Artec Space Spider showed the highest accuracy, the Bellus3D Dental Pro app may be the most feasible option for everyday clinical use due to its portability, ease of use, and low cost. This study presents three different systems, allowing readers to extrapolate to other systems when planning to introduce 3D photography in the clinical routine.

背景:针对表层软组织变化,尤其是整形和重建外科手术中表层软组织变化的新三维技术可以改善面部手术的规划和记录。本研究的目的是比较并确定三种不同的三维摄影系统在鼻部成像临床实践中的适用性和可行性:方法:这项前瞻性研究共纳入了 16 个健康的非手术鼻子。每个鼻子都制作了石膏模型,将其数字化并转换成 .stl 网格(= 地面实况模型)。然后使用 Artec Space Spider(黄金标准)、Planmeca ProFace® 和 Bellus3D Dental Pro 应用程序拍摄每个鼻子的三维图像。使用 MeshLab 软件将所有生成的 .stl 文件与地面实况模型对齐,并计算均方根误差 (RMSE)、平均表面距离 (MSD) 和豪斯多夫距离 (HD):结果:Artec Space Spider 三维摄影系统在均方根误差、平均表面距离和豪斯多夫距离方面的结果明显优于其他两个系统(各 p 为结论):所评估的三种三维照相系统都适用于临床常规的鼻部成像。虽然 Artec Space Spider 显示出最高的精确度,但 Bellus3D Dental Pro 应用程序因其便携性、易用性和低成本,可能是日常临床使用中最可行的选择。本研究介绍了三种不同的系统,使读者在计划将三维摄影引入临床常规时,可以推断出其他系统。
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引用次数: 0
Effects of physical activity levels on characteristic pain in temporomandibular dysfunctions: a cross-sectional study. 体育锻炼水平对颞下颌关节功能障碍特征性疼痛的影响:一项横断面研究。
IF 3 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-01-18 DOI: 10.1186/s13005-024-00407-3
Youngwoo Chun, Jung Hwan Jo, Ji Woon Park

Background: Physical activity is known to influence the symptoms of a variety of pain disorders including fibromyalgia and osteoarthritis although the underlying mechanism is not fully understood. In spite of the high prevalence of temporomandibular disorders (TMD), no previous study has objectively evaluated the relationship between TMD and general physical activity. This study aims to investigate the influence of physical activity on pain and disability from TMD, considering various confounders including sleep, systemic inflammation, psychosocial disturbances, and widespread pain.

Methods: This observational cross-sectional study is based on consecutive samples of 100 TMD patients (22 with high pain disability and 78 with low pain disability level). Physical activity levels were assessed with actigraph. Level of pain and disability were evaluated using the Graded Chronic Pain Scale. Hematologic examinations including inflammatory biomarkers were assessed and comorbidities were investigated with validated questionnaires. Differences were analyzed according to disability level.

Results: Patients with high disability level spent significantly more time doing both moderate (p = 0.033) and vigorous (p = 0.039) level physical activity. Light physical activity, on the other hand, was associated with low disability but the difference did not reach statistical significance. Time spent in light physical activity was significantly associated with high levels of pain and disability (p = 0.026, β = -0.001) and time spent in vigorous physical activity had significant predictive power (cutoff value 2.5 min per week, AUC 0.643, p = 0.041). Scores of the Jaw Function Limitation Score-20 (p = 0.001), present McGill Pain Score (p = 0.010), and number of people potentially diagnosed with fibromyalgia (p = 0.033) were significantly higher in the high disability group.

Conclusions: Moderate or vigorous physical activity is associated with worse TMD symptoms while light physical activity may be beneficial. Further research related to the amount and frequency of physical activity is necessary to establish clinical guidelines for TMD.

Trial registration: clinical trial registration of the Clinical Research Information Service of Republic of Korea (number KCT0007107).

背景:众所周知,体育锻炼可影响包括纤维肌痛和骨关节炎在内的多种疼痛疾病的症状,但其潜在机制尚未完全明了。尽管颞下颌关节紊乱症(TMD)的发病率很高,但以前没有任何研究客观地评估过 TMD 与一般体力活动之间的关系。本研究旨在调查体力活动对 TMD 引起的疼痛和残疾的影响,同时考虑到各种混杂因素,包括睡眠、全身炎症、社会心理障碍和广泛性疼痛:本观察性横断面研究基于 100 名 TMD 患者(22 名疼痛致残程度高,78 名疼痛致残程度低)的连续样本。采用运动计对患者的体力活动水平进行评估。使用慢性疼痛分级量表评估疼痛和残疾程度。对包括炎症生物标志物在内的血液学检查进行了评估,并通过有效的问卷调查对合并症进行了调查。根据残疾程度对差异进行了分析:结果:残疾程度高的患者花在中度(p = 0.033)和剧烈(p = 0.039)体力活动上的时间明显更多。另一方面,轻度体力活动与低残疾程度相关,但差异未达到统计学意义。轻度体力活动时间与疼痛和残疾程度高显著相关(p = 0.026,β = -0.001),而剧烈体力活动时间具有显著的预测能力(临界值为每周 2.5 分钟,AUC 0.643,p = 0.041)。高残疾组的颚功能限制评分-20(p = 0.001)、目前的麦吉尔疼痛评分(p = 0.010)和可能被诊断为纤维肌痛的人数(p = 0.033)均显著高于高残疾组:结论:中度或剧烈运动与 TMD 症状恶化有关,而轻度运动可能有益。有必要对体力活动的量和频率进行进一步研究,以制定 TMD 的临床指南。试验注册:大韩民国临床研究信息服务部临床试验注册(编号 KCT0007107)。
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引用次数: 0
Correction: Orthodontic treatment and biological limits: a retrospective clinical trial 更正:正畸治疗与生物极限:一项回顾性临床试验
IF 3 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-01-08 DOI: 10.1186/s13005-023-00405-x
Niki Nikoleta Tabancis, K. Krey, Franka Stahl, Valeria Behnke, A. Ratzmann
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引用次数: 0
Three-dimensional spatial analysis of temporomandibular joint in adolescent Class II division 1 malocclusion patients: comparison of Twin-Block and clear functional aligner. 青少年 II 类 1 分区错颌畸形患者颞下颌关节的三维空间分析:Twin-Block 和透明功能性矫治器的比较。
IF 3 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-01-06 DOI: 10.1186/s13005-023-00404-y
Yueying Zhang, Jiajing Zheng, Qiuyue Wu, Tianlu Jiang, Hua Xiao, Yusen Du, Yizhe Qi, Zuolin Jin, Feifei Li

Background: Our study aimed to use three-dimensional (3D) spatial morphological measurement methods to compare the influence of Twin-Block and clear functional aligners on the temporomandibular joint (TMJ) of adolescent Class II division 1 malocclusion mandibular retraction patients. We also aimed to explore the similarities and differences in the effects on the TMJ upon using Twin-Block and clear functional aligner.

Methods: Cone-beam computed tomography (CBCT) data of 49 patients with Class II division 1 malocclusion (Twin-Block group: 24; clear functional aligner group: 25) were collected before and after functional orthodontic treatment, and a 3D model of the TMJ was reconstructed using MIMICS 21.0 software. Eighteen measurement parameters, including the anterior, superior, and posterior joint spaces, were measured and compared using the 3D model.

Results: After the two groups underwent functional appliance treatment, the height, volume, and surface area of the condyle, length of the mandibular ramus and mandibular length increased; The retro-displaced condyle moved to the middle position of the articular fossa, while the rest of the condylar position did not change significantly. Remodeling of the articular fossa after treatment was not evident. The superior joint space of the clear functional aligner group increased, but there was no significant change after Twin-Block appliances treatment.

Conclusions: Both appliances promote condylar growth and sagittal and vertical development of the mandible in adolescent Class II division 1 malocclusion mandibular retraction patients. The length of the mandibular ramus showed a more significant increase following treatment with the Twin-Block appliances than with clear function aligners.

研究背景我们的研究旨在使用三维(3D)空间形态测量方法,比较Twin-Block和透明功能性矫治器对青少年II类1型错颌畸形下颌后缩患者颞下颌关节(TMJ)的影响。我们还旨在探索使用Twin-Block和透明功能性矫治器对颞下颌关节影响的异同:方法:我们收集了49名二类一区错颌畸形患者(Twin-Block组24人;透明功能性矫治器组25人)在功能性正畸治疗前后的锥形束计算机断层扫描(CBCT)数据,并使用MIMICS 21.0软件重建了颞下颌关节的三维模型。使用三维模型对包括前、上、后关节间隙在内的 18 个测量参数进行了测量和比较:结果:两组患者接受功能矫治器治疗后,髁突的高度、体积和表面积、下颌横突长度和下颌长度均有所增加;后脱位的髁突移至关节窝的中间位置,而髁突的其他位置没有明显变化。治疗后关节窝的重塑并不明显。透明功能性矫治器组的上关节间隙增大,但双阻生矫治器治疗后没有明显变化:结论:两种矫治器都能促进青少年 II 类 1 型错颌畸形下颌后缩患者的髁突生长以及下颌骨的矢状和垂直发育。与透明功能矫治器相比,Twin-Block矫治器治疗后下颌横突长度的增加更为明显。
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引用次数: 0
Prevalence of KIG-grades 3–5 in an orthodontic practice in North Rhine Westphalia compared with results of the DMS•6 and with KZBV data 北莱茵威斯特法伦州一家正畸诊所的 KIG 3-5 级患病率与 DMS-6 和 KZBV 数据的比较
IF 3 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-01-04 DOI: 10.1186/s13005-023-00402-0
Gero Stefan Michael Kinzinger, Jan Hourfar, Jörg Alexander Lisson
The prevalence of tooth and jaw malocclusions in 8- to 9-year-olds was surveyed in a nationwide setting as part of the orthodontic module of the Sixth German Study on Oral Health (DMS•6), using the orthodontic indication groups (KIG) as index. Aim of this study was the detection of the prevalence of malocclusions requiring treatment according to the KIG index in statutorily insured patients of an orthodontic practice in North Rhine Westphalia, Germany, and to compare results with corresponding DMS•6 and KZBV data. Between 2017–2021, n = 953 statutorily insured patients called for an initial consultation and subsequent determination of the KIG-classification and -grades. The malocclusions were classified and graded in the highest possible KIG-grade according to valid SHI guidelines. Multiple classifications were not recorded. KIG-grade > 3 according to the valid guidelines was detected in n = 815 patients. Since the DMS•6 does not contain information on KIG classifications "U" and "S", their inclusion was waived despite evaluation, leaving data from n = 683 patients for analysis and comparison. During the study period, n = 235 patients (34.4%) had KIG-classification "D". More than 10% were classified as "K" (120 patients, 17.6%), "P" (98 patients, 14.2%), "M" (89 patients, 13.0%), and "E" (81 patients, 11.9%). Of 16 possible classifications with KIG-grade > 3, "D4" was the most common with 26.6% (182 patients). The results confirm the findings from the multicentric DMS•6 from2021 and corresponding KZBV data from 2020. Sagittal deviations described by classifications "D" and "M" represent with 47.4% almost half of the malocclusions with treatment need. KIG-grade D4 is the most frequent classification. There were no regional deviations of the prevalence of KIG-grades 3–5 in the district of Viersen / North Rhine compared with the national average, not even when scrutinizing a five-year-period.
作为第六次德国口腔健康研究(DMS-6)正畸模块的一部分,该研究以正畸适应症组(KIG)为指标,在全国范围内调查了 8 至 9 岁儿童牙颌畸形的患病率。本研究的目的是根据 KIG 指数检测德国北莱茵威斯特法伦州一家正畸诊所的法定投保患者中需要治疗的畸形患病率,并将结果与相应的 DMS-6 和 KZBV 数据进行比较。2017-2021 年间,n = 953 名法定投保患者来院进行了初次咨询,随后确定了 KIG 分类和分级。根据有效的SHI指南,对畸形进行分类,并将其划分为最高的KIG等级。多重分级不记录在案。根据有效的指南,有 815 名患者的 KIG 等级大于 3。由于 DMS-6 不包含 KIG 分级 "U "和 "S "的信息,因此尽管进行了评估,但还是放弃了将其纳入研究范围,只留下了 n = 683 名患者的数据用于分析和比较。在研究期间,有 235 名患者(34.4%)的 KIG 分级为 "D"。超过 10% 的患者被分类为 "K"(120 名患者,17.6%)、"P"(98 名患者,14.2%)、"M"(89 名患者,13.0%)和 "E"(81 名患者,11.9%)。在 KIG 等级大于 3 的 16 种可能分类中,"D4 "最为常见,占 26.6%(182 名患者)。这些结果证实了 2021 年多中心 DMS-6 的研究结果和 2020 年 KZBV 的相应数据。"D "和 "M "分级描述的矢状位偏差占需要治疗的畸形的47.4%,几乎占到一半。KIG等级D4是最常见的分类。与全国平均水平相比,维埃森/北莱茵地区的 KIG 3-5 级患病率没有地区性偏差,即使对五年期进行审查也是如此。
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引用次数: 0
Physicochemical properties of AH plus bioceramic sealer, Bio-C Sealer, and ADseal root canal sealer AH 加生物陶瓷封闭剂、Bio-C 封闭剂和 ADseal 根管封闭剂的理化特性
IF 3 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-01-03 DOI: 10.1186/s13005-023-00403-z
Tamer M. Hamdy, Manar M. Galal, Amira Galal Ismail, Shehabeldin Saber
The aim of this study was to evaluate the physicochemical properties of two newly introduced premixed calcium silicate-based root canal sealers (AH Plus Bioceramic Sealer and Bio-C Sealer) compared to a resin-based root canal sealer (ADseal root canal sealer). Solubility, pH analysis, calcium ion release, and film thickness of each sealer were evaluated following ISO guidelines. The data were examined using the two-way ANOVA test. Furthermore, X-ray diffraction (XRD) examination was performed to investigate the crystalline phase of each type of sealer. X-ray fluorescence (XRF) analysis was done for the chemical elemental analysis of each sealer. The least film thickness, highest alkalinity, and highest calcium ion release were all displayed by AH Plus Bioceramic Sealer. High solubility, high alkalinity, intermediate calcium ion release, and intermediate film thickness were all displayed by Bio-C Sealer. While ADseal root canal sealer displayed the greatest film thickness, least solubility, alkalinity, and calcium ion release. Both AH Plus Bioceramic Sealer and Bio-C Sealer represented adequate properties to be considered a good sealer that could be used as a potential alternative to resin-based root canal sealers.
本研究旨在评估两种新推出的预混合硅酸钙根管封闭剂(AH Plus 生物陶瓷封闭剂和 Bio-C 封闭剂)与树脂根管封闭剂(ADseal 根管封闭剂)的物理化学特性。按照 ISO 指南对每种封闭剂的溶解性、pH 值分析、钙离子释放量和薄膜厚度进行了评估。数据采用双向方差分析检验。此外,还进行了 X 射线衍射(XRD)检查,以研究每种封孔剂的结晶相。X 射线荧光 (XRF) 分析用于对每种密封剂进行化学元素分析。AH Plus 生物陶瓷封闭剂的膜厚度最小、碱度最高、钙离子释放量最大。Bio-C 封闭剂具有高溶解度、高碱度、中等钙离子释放度和中等薄膜厚度。而 ADseal 根管封闭剂的膜厚度最大,溶解度、碱度和钙离子释放量最小。AH Plus 生物陶瓷封闭剂和 Bio-C 封闭剂都具有足够的特性,可被视为一种良好的封闭剂,可用作树脂根管封闭剂的潜在替代品。
{"title":"Physicochemical properties of AH plus bioceramic sealer, Bio-C Sealer, and ADseal root canal sealer","authors":"Tamer M. Hamdy, Manar M. Galal, Amira Galal Ismail, Shehabeldin Saber","doi":"10.1186/s13005-023-00403-z","DOIUrl":"https://doi.org/10.1186/s13005-023-00403-z","url":null,"abstract":"The aim of this study was to evaluate the physicochemical properties of two newly introduced premixed calcium silicate-based root canal sealers (AH Plus Bioceramic Sealer and Bio-C Sealer) compared to a resin-based root canal sealer (ADseal root canal sealer). Solubility, pH analysis, calcium ion release, and film thickness of each sealer were evaluated following ISO guidelines. The data were examined using the two-way ANOVA test. Furthermore, X-ray diffraction (XRD) examination was performed to investigate the crystalline phase of each type of sealer. X-ray fluorescence (XRF) analysis was done for the chemical elemental analysis of each sealer. The least film thickness, highest alkalinity, and highest calcium ion release were all displayed by AH Plus Bioceramic Sealer. High solubility, high alkalinity, intermediate calcium ion release, and intermediate film thickness were all displayed by Bio-C Sealer. While ADseal root canal sealer displayed the greatest film thickness, least solubility, alkalinity, and calcium ion release. Both AH Plus Bioceramic Sealer and Bio-C Sealer represented adequate properties to be considered a good sealer that could be used as a potential alternative to resin-based root canal sealers.","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":"91 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139083598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of diagnostic accuracy of cone beam computed tomography and multi-detector computed tomography for detection of anatomical variations in rhinoplasty 评估锥形束计算机断层扫描和多探测器计算机断层扫描在检测鼻整形术解剖变异方面的诊断准确性
IF 3 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-01-03 DOI: 10.1186/s13005-023-00401-1
Abdolreza Rouientan, Mohammad Bashir Khodaparast, Yaser Safi
Different imaging techniques, such as multi-detector computed tomography (MDCT) scan and cone beam computed tomography(CBCT), are used to check the structure of the nose before rhinoplasty. This study aimed to evaluate the accuracy of two imaging techniques, MDCT scan, and CBCT, in diagnosing structural Variations in rhinoplasty for the first time. This diagnostic accuracy study was conducted on 64 rhinoplasty candidates who complained of snoring and sleep apnea or had a positive result in the examination with Cottle’s maneuver or modified Cottle technique between February 2021 and October 2022 at 15- Khordad Hospital affiliated to Beheshti University of Medical Sciences. Before rhinoplasty, patients were randomly assigned to one of the CT and CBCT techniques with an equal ratio. Scans were assessed for the presence of Nasal septum deviation (NSD), Mucocele, Concha bullosa, and nasal septal spur by two independent radiologists. The findings of the two methods were evaluated with the results during rhinoplasty as the gold standard. NSD was the most common anatomical variation based on both imaging techniques. The accuracy of CBCT for diagnosing Nasal Septum Deviation and Mucocele was 80% and 75%, respectively. The sensitivity, specificity, and accuracy of CBCT in detecting Concha bullosa were 81.3% and 83.3%, respectively. The Kappa coefficient between CBCT and intraoperative findings for diagnosing NSD and Concha Bullosa was 0.76 and 0.73, respectively (p < 0.05). CBCT can be considered a suitable method with high accuracy and quality to evaluate the anatomical variations before rhinoplasty.
不同的成像技术,如多探测器计算机断层扫描(MDCT)和锥形束计算机断层扫描(CBCT),被用于鼻整形术前检查鼻部结构。本研究旨在首次评估 MDCT 扫描和 CBCT 这两种成像技术在诊断鼻整形术结构变异方面的准确性。这项诊断准确性研究于 2021 年 2 月至 2022 年 10 月期间在贝赫什提医科大学附属 15- Khordad 医院对 64 名主诉打鼾和睡眠呼吸暂停或在科特尔手法或改良科特尔技术检查中结果呈阳性的鼻整形候选人进行。鼻整形术前,患者被随机分配到 CT 和 CBCT 技术中的一种,比例相同。由两名独立的放射科医生对扫描结果进行评估,以确定是否存在鼻中隔偏曲(NSD)、鼻囊肿、牛皮癣和鼻中隔骨刺。两种方法的检查结果均以鼻整形手术的结果作为金标准进行评估。根据两种成像技术,NSD 是最常见的解剖变异。CBCT 诊断鼻中隔偏曲和黏液瘤的准确率分别为 80% 和 75%。CBCT 检测牛皮癣的敏感性、特异性和准确性分别为 81.3% 和 83.3%。在诊断 NSD 和牛皮癣方面,CBCT 与术中发现的卡帕系数分别为 0.76 和 0.73(P < 0.05)。可以认为,CBCT 是鼻整形术前评估解剖变异的一种高精度、高质量的合适方法。
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引用次数: 0
Morphological aspects and distribution of granules composed of deproteinized bovine bone or human dentin into a putty mixture: an in vitro study 腻子混合物中由去蛋白牛骨或人牙本质组成的颗粒的形态和分布:体外研究
IF 3 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-12-18 DOI: 10.1186/s13005-023-00398-7
Inês Pimentel, Bruno Henriques, Filipe Silva, Oscar Carvalho, Wim Teughels, Mutlu Özcan, Júlio C. M. Souza
The main aim of this study was to evaluate the morphological aspects and distribution of granules composed of deproteinized bovine bone mineral (DBBM) and human dentin-derived bone graft (HDBG) into a putty consistency mixture. DBBM or HDBG were mixed with an alginate-based hydrogel at two different granule/hydrogel ratio (1:1 and 1:3) and divided into four test groups while two control groups were composed of DBBM or HDBG free of hydrogel. Groups of specimens were cross-sectioned for morphological evaluation by scanning electron microscopy (SEM) at backscattered electrons mode. Details on the dimensions and pores’ size of DBBM and HDBG were evaluated after mixing different amounts of particles and alginate-based hydrogels. Microscopic analyses revealed a size of DBBM granules ranging from 750 up to 1600 μm while HDBG particles showed particle size ranging from 375 up to 1500 μm. No statistical differences were identified regarding the size of granules (p > 0.5). The mean values of pores’ size of DBBM particles were noticed at around 400 μm while HDBG particles revealed micro-scale pores of around 1–3 μm promoted by the dentin tubules (p < 0.05). The lowest distance between particles was at 125 μm for HDBG and 250 μm for DBBM when the particle content was increased. On decreasing the particles’ content, the distance between particles was larger for DBBM (~ 1000 μm) and HDBG (~ 1100 μm). In fact, statistically significant differences were found when the content of granules increased (p < 0.05). The increased content of bioactive ceramic granules in a putty consistency mixture with hydrogel decreased the space among granules that can promote a high ceramic density and stimulate the bone growth over the healing process. Macro-scale pores on bovine bone mineral granules stimulate the formation of blood vessels and cell migration while the micro-scale pores of dentin-derived granules are proper for the adsorption of proteins and growth of osteogenic cells on the bone healing process. A high amount of bioactive ceramic granules should be considered when mixing with hydrogels as a putty material since that result in small spaces among granules maintaining the bone volume over the bone healing process. Deproteinized bovine bone mineral granules have macro-scale pores providing an enhanced angiogenesis while dentin-derived granules possess only micro-scale pores for the adsorption of proteins and proliferation of osteogenic cells on the bone healing process. Further studies should evaluate the combination of different bioactive ceramic materials for enhanced bone healing.
本研究的主要目的是评估由去蛋白牛骨矿物质(DBBM)和人牙本质骨移植物(HDBG)组成的颗粒在腻子稠度混合物中的形态和分布。DBBM 或 HDBG 以两种不同的颗粒/水凝胶比例(1:1 和 1:3)与藻酸盐水凝胶混合,并分为四个试验组,而两个对照组则由不含水凝胶的 DBBM 或 HDBG 组成。利用扫描电子显微镜(SEM)在背散射电子模式下对各组试样进行横截面形态评估。在混合了不同数量的颗粒和海藻酸盐水凝胶后,对 DBBM 和 HDBG 的尺寸和孔隙大小进行了详细评估。显微分析表明,DBBM 颗粒的大小从 750 到 1600 微米不等,而 HDBG 颗粒的大小从 375 到 1500 微米不等。颗粒大小没有统计学差异(p > 0.5)。DBBM 颗粒的孔径平均值约为 400 μm,而 HDBG 颗粒在牙本质小管的促进下显示出约 1-3 μm 的微尺度孔隙(p < 0.05)。当颗粒含量增加时,HDBG 颗粒间的最小距离为 125 μm,DBBM 颗粒间的最小距离为 250 μm。颗粒含量降低时,DBBM(约 1000 μm)和 HDBG(约 1100 μm)的颗粒间距更大。事实上,当颗粒含量增加时,两者之间的差异具有统计学意义(p < 0.05)。腻子稠度混合物中生物活性陶瓷颗粒与水凝胶含量的增加减少了颗粒之间的空隙,从而促进了陶瓷的高密度,并在愈合过程中刺激了骨的生长。牛骨矿物颗粒上的大尺度孔隙可刺激血管的形成和细胞的迁移,而牙本质衍生颗粒的微尺度孔隙则有利于蛋白质的吸附和成骨细胞在骨愈合过程中的生长。在将大量生物活性陶瓷颗粒与水凝胶混合作为腻子材料时,应考虑在骨愈合过程中保持颗粒间的小空间,以保持骨量。去蛋白牛骨矿物质颗粒具有大尺度孔隙,可增强血管生成,而牙本质衍生颗粒仅具有微尺度孔隙,可在骨愈合过程中吸附蛋白质和增殖成骨细胞。进一步的研究应评估不同生物活性陶瓷材料的组合,以促进骨愈合。
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引用次数: 0
Three-dimensional quantification of mandibular asymmetries in Caucasian adult patients with different sagittal and vertical skeletal patterns. A cone beam study using 3D segmentation and mirroring procedures 对具有不同矢状和垂直骨骼模式的高加索成年患者的下颌骨不对称进行三维量化。使用三维分割和镜像程序的锥形束研究
IF 3 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-12-14 DOI: 10.1186/s13005-023-00400-2
Pilar España-Pamplona, Natalia Zamora-Martinez, Beatriz Tarazona-Álvarez, Valmy Pangrazio-Kulbersh, Vanessa Paredes-Gallardo
An accurate identification of mandibular asymmetries is required by modern orthodontics and orthognathic surgery to improve diagnosis and treatment planning of such deformities. Although craniofacial deformities are very frequent pathologies, some types of asymmetries can be very difficult to assess without the proper diagnostic tools. The purpose of this study was to implement the usage of three-dimensional (3D) segmentation procedures to identify asymmetries at the mandibular level in adult patients with different vertical and sagittal patterns where the asymmetries could go unnoticed at the observational level. The study sample comprised 60 adult patients (33 women and 27 men, aged between 18 and 60 years). Subjects were divided into 3 sagittal and vertical skeletal groups. CBCT images were segmented, mirrored and voxel-based registered with reference landmarks using ITK-SNAP® and 3DSlicer® software’s. 3D surface models were constructed to evaluate the degree of asymmetry at different anatomical levels. There was a degree of asymmetry, with the left hemimandible tending to contain the right one (0.123 ± 0.270 mm (CI95% 0.036–0.222; p < 0.001). Although the subjects under study did not present significant differences between mandibular asymmetries and their sagittal or vertical skeletal pattern (p = 0.809 and p = 0.453, respectively), a statistically significant difference has been found depending on the anatomical region (p < 0.001; CI95%=1.020–1.021), being higher in the condyle, followed by the ramus and the corpus. Although mandibular asymmetries cannot be correlated with vertical and sagittal skeletal patterns in symmetric patients, knowledge about 3D segmentation procedures and color maps can provide valuable information to identify mandibular asymmetries.
现代正畸和正颌外科需要准确识别下颌不对称,以提高对此类畸形的诊断和治疗计划。虽然颅面畸形是非常常见的病理,但如果没有适当的诊断工具,某些类型的不对称很难评估。本研究的目的是使用三维(3D)分割程序来识别具有不同垂直和矢状模式的成年患者下颌水平的不对称,这些不对称在观察水平上可能被忽视。研究样本包括60名成年患者(33名女性和27名男性,年龄在18至60岁之间)。受试者分为3个矢状和垂直骨骼组。使用ITK-SNAP®和3DSlicer®软件对CBCT图像进行分割、镜像和基于体素的参考地标配准。构建三维表面模型来评估不同解剖水平的不对称程度。有一定程度的不对称,左半下颚倾向于包含右半下颚(0.123±0.270 mm) (CI95% 0.036-0.222;p < 0.001)。尽管研究对象在下颌不对称与其矢状或垂直骨骼模式之间没有显着差异(分别为p = 0.809和p = 0.453),但根据解剖区域的不同,统计学上存在显着差异(p < 0.001;CI95%= 1.020-1.021),在髁上最高,其次是支和体。虽然下颌不对称不能与对称患者的垂直和矢状骨骼模式相关,但关于三维分割程序和彩色地图的知识可以为识别下颌不对称提供有价值的信息。
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引用次数: 0
Orthodontic treatment and biological limits: a retrospective clinical trial 正畸治疗和生物极限:一项回顾性临床试验
IF 3 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-12-14 DOI: 10.1186/s13005-023-00399-6
Niki Nikoleta Tabancis, Karl-Friedrich Krey, Franka Stahl, Valeria Behnke, Anja Ratzmann
The fundamental part of every successful orthodontic treatment is the detailed treatment planning including a precise determination of the virtual treatment objective (VTO) while considering the biological and anatomical limits. The aim of this study is to investigate and to compare the feasibility of the established reference values before and after orthodontic treatment and to determine the usefulness of this parameters as guidance for the sagittal anterior, sagittal posterior and transverse biological boundaries. Thirty-two patients aged 9 to 18 years (12 male and 20 female) with all permanent teeth present were randomly selected for orthodontic treatment with fixed multibracket appliance regardless of the potential malocclusion. The parameters 6-PTV, 1-NB [mm] and the WALA ridge were set for the identification of the transverse, sagittal anterior and sagittal posterior tooth position. The measurements were carried out at the beginning (T0) and at the end (T1) of the orthodontic treatment. They were set in relation with their individual threshold values (G). After the results of the measurements were conducted using the software OnyxCeph3TM (version 3.2.185 (505), Image Instruments GmbH, Chemnitz, DE), they were statistically calculated in the software RStudio (2022.12.0 Build 353 © 2009–2022 Posit Software PBC). Among the 32 patients, the mean pre- and post-treatment changes measured through the three parameters in relation to the individual reference values were statistically significant (p < 0.01). The mean values for 6-PTV, 1-NB and the WALA ridge amounted 15.37 mm, 2.56 mm and 4.23 mm at the beginning of the treatment, while after the treatment the measured values amounted 20.31 mm, 2.4 mm and 5.55 mm. These measurements combined with the statistical analysis of the changes of WALA ridge (T0, T1) confirmed that the teeth have been successfully uprighted and aligned. Furthermore, the maxillary first molars have been moved slightly mesially, as proven by the changes in 6-PTV, without certainty as to whether bodily movement or mesial tipping took place. Additionally, the lower incisors have been protruded, slightly exceeding the individual threshold values. The parameters investigated provide a suitable assessment tool for recording the limits of the sagittal posterior, the sagittal anterior and the transverse dimension.
每一个成功的正畸治疗的基本部分是详细的治疗计划,包括精确确定虚拟治疗目标(VTO),同时考虑到生物学和解剖学的限制。本研究的目的是调查和比较正畸治疗前后建立的参考值的可行性,并确定这些参数作为指导矢状面前、矢状面后和横向生物边界的有用性。随机选择32例9 ~ 18岁,所有恒牙均存在的患者(男12例,女20例),不论是否存在错颌,均采用固定多托矫治器进行正畸治疗。设置参数6-PTV, 1-NB [mm]和WALA脊,用于识别横、矢状前、矢状后牙位置。测量分别在正畸治疗开始(T0)和结束(T1)进行。在使用OnyxCeph3TM (version 3.2.185 (505), Image Instruments GmbH, Chemnitz, DE)软件进行测量结果后,在RStudio软件(2022.12.0 Build 353©2009-2022 Posit software PBC)中进行统计计算。在32例患者中,通过三个参数测量的治疗前后平均变化与个体参考值的关系均有统计学意义(p < 0.01)。治疗开始时6-PTV、1-NB和WALA脊的平均值分别为15.37 mm、2.56 mm和4.23 mm,治疗后测量值分别为20.31 mm、2.4 mm和5.55 mm。这些测量结果结合WALA牙脊(T0, T1)变化的统计分析,证实牙齿已成功矫直和对齐。此外,上颌第一磨牙有轻微的近端移动,正如6-PTV的变化所证明的,但不确定是否发生了身体运动或近端倾斜。此外,下门牙已突出,略超过个别阈值。所研究的参数为记录矢状面后、矢状面前和横向尺寸的界限提供了合适的评估工具。
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Head & Face Medicine
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