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The Evolving Paradigm of Intracoronary Tirofiban Administration in STEMI STEMI 冠状动脉内替罗非班用药范式的演变。
IF 2.2 4区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-11-01 DOI: 10.1016/j.hlc.2024.10.004
Mohammad Sarraf MD, Vinayak Nagaraja MBBS, MBiostat, FRACP
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引用次数: 0
Cardiac Society of Australia and New Zealand 澳大利亚和新西兰心脏病学会
IF 2.2 4区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-11-01 DOI: 10.1016/S1443-9506(24)01856-0
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引用次数: 0
Cardiovascular Risk Factors and Disparities in Management of Embolic Stroke: A Western Sydney Perspective 心血管风险因素与栓塞性中风管理中的差异:西悉尼视角
IF 2.2 4区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-11-01 DOI: 10.1016/j.hlc.2024.04.300
Vlad Danaila MD , Prakesh Vaheisvaran MD , Aaisha Ferkh MD , Sai Nagaratnam MD , Amy Clark BSc , Peter Emerson MD , Luke Stefani BSc , Andrew Duggins PhD , Paula Brown BSc , Aravinda Thiagalingam PhD , A. Robert Denniss PhD , Eddy Kizana PhD , Liza Thomas PhD

Background

Ischaemic stroke remains one of the leading causes of death and disability worldwide. The population of Western Sydney has a unique demographic with lower socioeconomic status and a culturally and linguistically diverse population. This study aims to investigate the demographics and cardiovascular risk factors of patients in Western Sydney, focusing on the prevalence and profile of cardioembolic (CE) strokes and embolic strokes of undetermined source (ESUS).

Method

Prospective data were collected in 463 patients with ischaemic stroke presenting to a tertiary centre in Western Sydney, who underwent predischarge transthoracic echocardiography. Patients with haemorrhagic strokes or unclear stroke diagnosis were excluded. Analysis of stroke subtype (CE, ESUS, or non-embolic) and clinical characteristics was performed based on age, gender, and prior atrial fibrillation (AF) prevalence.

Results

Of the 463 patients, 147 (32%) had CE strokes, and 147 (32%) had ESUS. Cardioembolic (CE) strokes were associated with older age (≥65 years) and a history of congestive cardiac failure. Older patients had higher rates of hypertension, ischaemic heart disease, AF, and congestive heart failure. History of AF was present in 67 patients (14.5%); however, only 51% received anticoagulation before admission despite a low bleeding risk. The transthoracic echocardiography characteristics of ESUS/non-embolic strokes differed from those of CE strokes; 20% of patients with ESUS had an enlarged left atrium, suggesting a subset of patients with ESUS with a left atrial myopathy.

Conclusions

Patients with ischaemic stroke in Western Sydney have a high prevalence of cardiovascular risk factors which were often undertreated. Half of the patients with prior AF did not receive anticoagulation despite low bleeding risk, indicating a gap in optimal stroke prevention. There were distinct echocardiographic characteristics among stroke subtypes. Further analysis of left atrium parameters may provide greater insights into the pathogenesis and prevention of embolic strokes.
背景:缺血性中风仍是导致全球死亡和残疾的主要原因之一。西悉尼的人口结构独特,社会经济地位较低,文化和语言多元化。本研究旨在调查西悉尼患者的人口统计学和心血管风险因素,重点关注心肌栓塞性脑卒中(CE)和来源不明的栓塞性脑卒中(ESUS)的发病率和概况:方法:在悉尼西部的一家三级医疗中心收集了 463 名缺血性脑卒中患者的前瞻性数据,这些患者在出院前均接受了经胸超声心动图检查。出血性中风或中风诊断不明确的患者被排除在外。根据年龄、性别和既往房颤(AF)患病率对中风亚型(CE、ESUS或非栓塞性)和临床特征进行了分析:在463名患者中,147人(32%)患有CE脑卒中,147人(32%)患有ESUS脑卒中。心肌栓塞性脑卒中与年龄较大(≥65 岁)和充血性心力衰竭病史有关。老年患者患高血压、缺血性心脏病、房颤和充血性心力衰竭的比例较高。67名患者(14.5%)有房颤病史;然而,尽管出血风险较低,但只有51%的患者在入院前接受了抗凝治疗。ESUS/非栓塞性脑卒中的经胸超声心动图特征与CE脑卒中不同;20%的ESUS患者左心房增大,这表明ESUS患者中有一部分患有左心房肌病:结论:西悉尼缺血性脑卒中患者的心血管风险因素发生率较高,且往往治疗不足。半数既往有房颤的患者尽管出血风险较低,但并未接受抗凝治疗,这表明在最佳卒中预防方面还存在差距。中风亚型的超声心动图特征各不相同。对左心房参数的进一步分析可能会为栓塞性中风的发病机制和预防提供更多信息。
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引用次数: 0
Letter to the Editor: “Improving Risk Analysis for Fatal Thrombosis in COVID-19: A Call for Targeted Anticoagulation” regarding: “Incidence, Predictors, and Outcomes of Venous and Arterial Thrombosis in COVID-19: A Nationwide Inpatient Analysis” by Agrawal et al. Heart Lung Circ. 2024;33(11):1563–73 致编辑的信:"改进 COVID-19 致命性血栓形成的风险分析:关于 "COVID-19 中静脉和动脉血栓形成的发生率、预测因素和预后:呼吁有针对性的抗凝治疗 "的编辑信函:Agrawal等人的 "COVID-19中静脉和动脉血栓形成的发生率、预测因素和结果:Agrawal等人撰写的 "COVID-19中静脉和动脉血栓形成的发生率、预测因素和结果:全国住院患者分析",《心肺循环》,2024;33(11):1563-73。
IF 2.2 4区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-11-01 DOI: 10.1016/j.hlc.2024.10.002
Chia Siang Kow MPharm , Dinesh Sangarran Ramachandram MSc , Syed Shahzad Hasan PhD , Kaeshaelya Thiruchelvam PhD
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引用次数: 0
Letter to the Editor Regarding “The Cardiovascular Conundrum: Navigating Semaglutide Shortages and Patient Well-being” 致编辑的信,内容涉及 "心血管难题:驾驭塞马鲁肽短缺与患者福祉"。
IF 2.2 4区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-11-01 DOI: 10.1016/j.hlc.2024.04.311
Alasdair Leslie MBBS, MBEE , Joshua Kovoor MBBS , Stephen Bacchi MBBS, PhD
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引用次数: 0
A Rare and Fatal Intersection: Pulmonary Atresia Complicated by Major Aortopulmonary Collateral Artery Dissection. 罕见的致命交叉:肺动脉闭锁并发大动脉-肺动脉侧支交叉。
IF 2.2 4区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-10-10 DOI: 10.1016/j.hlc.2024.06.1036
Ping Hu, Jie Wang, Xiao-Jing Ma
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引用次数: 0
Outcomes of the Modified Warden Procedure for Partial Anomalous Pulmonary Venous Connection Drainage to a High Location in the Superior Vena Cava. 将部分异常肺静脉连接引流至上腔静脉高位的改良 Warden 手术的效果。
IF 2.2 4区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-10-10 DOI: 10.1016/j.hlc.2024.06.1038
Chunjie Mu, Yi Song, Jianming Xia, Ning Cao, Yao Deng, Minzhang Zhao, Runwei Ma

Aim: To report the safety and effectiveness of a modified Warden procedure.

Method: Twenty-six (26) patients underwent modified Warden surgery at our centre from September 2017 to September 2021. In all patients, the superior vena cava (SVC) was reconstructed by turning the atrial wall in the main body of the right atrium upwards and applying fresh autologous pericardial patches. There were 13 male patients and 13 female patients, and the median age of the patients was 7.0 (range, 0.3-47.0) years. The median follow-up time after surgery was 47.0 (range, 32.0-80.0) months.

Results: The aortic cross-clamp time was 108.50±34.72 minutes, the cardiopulmonary bypass time was 154.81±41.65 minutes, the median postoperative mechanical ventilation time was 8.5 (range, 0.0-91.0) hours, the median intensive care unit stay was 43.5 (range, 15.0-352.0) hours, and the median length of postoperative hospital stay was 7.0 (range, 6.0-19.0) days. All patients were safely and successfully discharged from the hospital. No deaths or sinus node dysfunction occurred during the follow-up period. The mean gradient of the reconstructed SVC and/or the right pulmonary vein (PV) increased in eight patients and decreased to less than 1 mmHg in six patients. One (1) adult patient had already undergone two vascular interventions, and one child had persistent stenosis but did not undergo reoperation at the time of the study. In addition, two patients were subjected to pericardial windowing.

Conclusions: A modified Warden technique using a right atrial flap and autologous pericardium effectively corrected the high-plane connection between the PVs and SVC. This technique effectively avoids sinus node dysfunction; however, a short-term increase in the differential pressure of the re-established SVC or PV after the procedure is acceptable, and reintervention is required only in rare cases.

目的:报告改良Warden手术的安全性和有效性:2017年9月至2021年9月,26名患者在本中心接受了改良Warden手术。在所有患者中,通过将右心房主体的心房壁向上翻转并应用新鲜的自体心包补片重建上腔静脉(SVC)。患者中有 13 名男性和 13 名女性,中位年龄为 7.0 岁(0.3-47.0 岁)。术后中位随访时间为 47.0 个月(32.0-80.0 个月):主动脉瓣关闭时间为(108.50±34.72)分钟,心肺旁路时间为(154.81±41.65)分钟,术后机械通气时间中位数为8.5(0.0-91.0)小时,重症监护室住院时间中位数为43.5(15.0-352.0)小时,术后住院时间中位数为7.0(6.0-19.0)天。所有患者均安全顺利出院。随访期间没有发生死亡或窦房结功能障碍。8名患者重建后的SVC和/或右肺静脉(PV)的平均梯度有所增加,6名患者的梯度降至1 mmHg以下。其中一(1)名成人患者已接受过两次血管介入治疗,一名儿童患者血管持续狭窄,但在研究期间没有接受再次手术。此外,两名患者接受了心包开窗术:结论:使用右心房瓣和自体心包的改良 Warden 技术能有效矫正上腔静脉和下腔静脉之间的高平面连接。该技术可有效避免窦房结功能障碍;不过,术后重建的 SVC 或 PV 的压差短期内增加是可以接受的,只有在极少数情况下才需要重新介入。
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引用次数: 0
Designing the built environment for more walkable, liveable local neighbourhoods 设计建筑环境,打造更适合步行、更适合居住的地方社区
IF 2.2 4区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-09-18 DOI: 10.1016/j.hlc.2024.09.002
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引用次数: 0
Letter to the Editor Regarding “A Meta-Analysis of RCTs Comparing DOACs Against Warfarin for the Treatment of Left Ventricular Thrombus” 致编辑的信,内容涉及 "比较 DOAC 与华法林治疗左心室血栓的 RCT 的 Meta 分析"。
IF 2.2 4区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-09-18 DOI: 10.1016/j.hlc.2024.06.1034
Sara Khalid MBBS , Tobin Joseph MBBS , W. Yus Haniff W. Isa MBBS , Heerajnarain Bulluck PhD
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引用次数: 0
Infective Endocarditis Involving Bicuspid Aortic Valve, Native and Post-Aortic Valve Replacement (AVR): A Word of Caution! 原发性和主动脉瓣置换术(AVR)后涉及双尖瓣的感染性心内膜炎:注意事项!
IF 2.2 4区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-09-18 DOI: 10.1016/j.hlc.2024.09.003
Jaishanker Raman MMed, FRACS, PhD , Pankaj Saxena FRACS, PhD
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Heart, Lung and Circulation
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