Pub Date : 2026-01-01DOI: 10.1016/j.hlc.2025.10.011
Jacob P. George MBBS , Rebecca Kozor PhD, FRACP, FCSANZ
{"title":"Reply to Letter to the Editor “Reconsidering the Roles of Computed Tomography Coronary Angiography and Stress Echocardiography in Acute Chest Pain” regarding “Computed Tomography Coronary Angiography Versus Stress Echocardiography in a Rapid Access Chest Pain Clinic”","authors":"Jacob P. George MBBS , Rebecca Kozor PhD, FRACP, FCSANZ","doi":"10.1016/j.hlc.2025.10.011","DOIUrl":"10.1016/j.hlc.2025.10.011","url":null,"abstract":"","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"35 1","pages":"Page e11"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145904220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.hlc.2025.12.013
C. Lac, H. Dimitri, J. Assad, J. Tan
{"title":"Corrigendum to: Abstract 402, Vol 34, Supplement 4, Page S359 (2025) (Abstracts for the 73rd Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, 14–17 August 2025) entitled ‘Validation of Device-Detected Sleep Apnoea Using Polysomnography in a Subset of Heart Failure Patients’","authors":"C. Lac, H. Dimitri, J. Assad, J. Tan","doi":"10.1016/j.hlc.2025.12.013","DOIUrl":"10.1016/j.hlc.2025.12.013","url":null,"abstract":"","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"35 1","pages":"Page e17"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145904226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.hlc.2025.07.015
Yeliz Guler MD
{"title":"Reply to Letter to the Editor Regarding: “Albumin-Bilirubin Score for Contrast-Induced Acute Kidney Injury Prediction in STEMI: Critical Limitations”","authors":"Yeliz Guler MD","doi":"10.1016/j.hlc.2025.07.015","DOIUrl":"10.1016/j.hlc.2025.07.015","url":null,"abstract":"","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"35 1","pages":"Pages e7-e8"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145904223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.hlc.2025.12.014
R. Gandhi ∗, M. Zwartes, M. Hordern, A. Ranchord, P. Matsis, A. Sasse, A. Rama-Chandran, G. Prescott-Whitaker, A. Ishver, A. Chatfield
{"title":"Corrigendum to: Abstract 984, Vol 34, Supplement 4, Page S718 (2025) (Abstracts for the 73rd Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, 14–17 August 2025) entitled ‘TAVI With Cardiologist-Led Sedation – A Single-Centre Experience of Safety and Cost-Effectiveness in New Zealand’","authors":"R. Gandhi ∗, M. Zwartes, M. Hordern, A. Ranchord, P. Matsis, A. Sasse, A. Rama-Chandran, G. Prescott-Whitaker, A. Ishver, A. Chatfield","doi":"10.1016/j.hlc.2025.12.014","DOIUrl":"10.1016/j.hlc.2025.12.014","url":null,"abstract":"","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"35 1","pages":"Page e18"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145904227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.hlc.2025.08.027
Vishal Goel MBBS , William Chan MBBS, PhD , Jack Tan MBBS , Sidney Lo MBBS , Adam J. Nelson MBBS, PhD , Dion Stub MBBS, PhD , Derek Chew MBBS, PhD
Cardiogenic shock (CS) is characterised by tissue hypoxia as a result of circulatory failure arising from inadequate cardiac output and is commonly a complication of acute myocardial infarction (AMI). Despite improvement in reperfusion strategies for AMI, the survival among patients with CS remains poor. While mechanical circulatory support (MCS) technologies in AMI-CS offer promise, they have not translated to consistent improvements in patient survival, which may reflect an inability to recognise evolving CS at a reversible stage. Hence, reducing the mortality from CS requires solutions focused on timely diagnosis. CS is heterogenous, being dependent on interpreting acute haemodynamics and biomarkers, which often delays diagnosis and intervention. The continued digitisation of health information, particularly within the emergency and acute care environments has made the development of artificial intelligence (AI)-driven diagnostic decision support for the acutely deteriorating patient feasible. Such approaches have been effectively deployed in hospitals to alert frontline staff or “shock teams” to patient deterioration, with evidence of reductions in mortality. Further, these integrated systems that can “dynamically phenotype” patients and their clinical deterioration within the flow of data not only support clinical decision-making but also allow the establishment of virtual clinical registries assimilated within real-world practice, continuously evaluating clinical practice and outcomes. This review aims to delineate CS pathophysiology, limitations within our current diagnostic approach, understand the difficulties in conducting randomised clinical trials and explores the role of an integrated AI-based approach for early diagnosis and intervention in patients with CS.
{"title":"Will Dynamic Evaluation of Cardiogenic Shock Using Machine Learning Models Lead to Improved Survival?","authors":"Vishal Goel MBBS , William Chan MBBS, PhD , Jack Tan MBBS , Sidney Lo MBBS , Adam J. Nelson MBBS, PhD , Dion Stub MBBS, PhD , Derek Chew MBBS, PhD","doi":"10.1016/j.hlc.2025.08.027","DOIUrl":"10.1016/j.hlc.2025.08.027","url":null,"abstract":"<div><div>Cardiogenic shock (CS) is characterised by tissue hypoxia as a result of circulatory failure arising from inadequate cardiac output and is commonly a complication of acute myocardial infarction (AMI). Despite improvement in reperfusion strategies for AMI, the survival among patients with CS remains poor. While mechanical circulatory support (MCS) technologies in AMI-CS offer promise, they have not translated to consistent improvements in patient survival, which may reflect an inability to recognise evolving CS at a reversible stage. Hence, reducing the mortality from CS requires solutions focused on timely diagnosis. CS is heterogenous, being dependent on interpreting acute haemodynamics and biomarkers, which often delays diagnosis and intervention. The continued digitisation of health information, particularly within the emergency and acute care environments has made the development of artificial intelligence (AI)-driven diagnostic decision support for the acutely deteriorating patient feasible. Such approaches have been effectively deployed in hospitals to alert frontline staff or “shock teams” to patient deterioration, with evidence of reductions in mortality. Further, these integrated systems that can “dynamically phenotype” patients and their clinical deterioration within the flow of data not only support clinical decision-making but also allow the establishment of virtual clinical registries assimilated within real-world practice, continuously evaluating clinical practice and outcomes. This review aims to delineate CS pathophysiology, limitations within our current diagnostic approach, understand the difficulties in conducting randomised clinical trials and explores the role of an integrated AI-based approach for early diagnosis and intervention in patients with CS.</div></div>","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"35 1","pages":"Pages 12-30"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145458480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Out-of-hospital cardiac arrest (OHCA) remains a leading cause of mortality, with uncertain benefits of urgent coronary angiography (CAG) in non-ST-elevation myocardial infarction cases. Current guidelines lack clarity on the optimal timing of CAG for OHCA survivors. This study investigates the impact of CAG timing on in-hospital mortality and neurological outcomes in non-traumatic OHCA patients. It also identifies clinical predictors of poor prognosis.
Method
A retrospective cohort study was conducted at Fiona Stanley Hospital, Western Australia, analysing 223 non-traumatic OHCA patients admitted between February 2015 and December 2022. Patients were categorised into three CAG timing groups: immediate (<2 hours), intermediate (2–24 hours), and delayed (>24 hours). Multivariate logistic regression was used to assess independent predictors of mortality and neurological outcomes.
Results
Mortality was significantly higher in patients who received immediate or intermediate CAG compared to those who received delayed CAG. Delayed CAG was associated with better survival. Independent predictors of in-hospital mortality included lower pH, lower systolic blood pressure, lower Glasgow Coma Scale score on arrival, and diabetes.
Conclusions
Our findings do not support routine immediate CAG in non-ST-elevation myocardial infarction OHCA. A selective, delayed approach after hemodynamic stabilisation may improve survival. Clinicians should prioritise stabilisation before CAG, using pH, systolic blood pressure, and Glasgow Coma Scale as key prognostic indicators.
{"title":"Non-Traumatic Out-of-Hospital Cardiac Arrest at Fiona Stanley Hospital: In-Hospital Mortality Predictors and Timing of Coronary Angiography—A Retrospective Observational Cohort Study","authors":"Hendry Ramly MBBS , David Manners FRACP, MClinRes , Jenny Luong MBBS , Cian Murray MBBS , Christopher Judkins MBBS, MClinRes, PhD","doi":"10.1016/j.hlc.2025.06.007","DOIUrl":"10.1016/j.hlc.2025.06.007","url":null,"abstract":"<div><h3>Background & Aim</h3><div>Out-of-hospital cardiac arrest (OHCA) remains a leading cause of mortality, with uncertain benefits of urgent coronary angiography (CAG) in non-ST-elevation myocardial infarction cases. Current guidelines lack clarity on the optimal timing of CAG for OHCA survivors. This study investigates the impact of CAG timing on in-hospital mortality and neurological outcomes in non-traumatic OHCA patients. It also identifies clinical predictors of poor prognosis.</div></div><div><h3>Method</h3><div>A retrospective cohort study was conducted at Fiona Stanley Hospital, Western Australia, analysing 223 non-traumatic OHCA patients admitted between February 2015 and December 2022. Patients were categorised into three CAG timing groups: immediate (<2 hours), intermediate (2–24 hours), and delayed (>24 hours). Multivariate logistic regression was used to assess independent predictors of mortality and neurological outcomes.</div></div><div><h3>Results</h3><div>Mortality was significantly higher in patients who received immediate or intermediate CAG compared to those who received delayed CAG. Delayed CAG was associated with better survival. Independent predictors of in-hospital mortality included lower pH, lower systolic blood pressure, lower Glasgow Coma Scale score on arrival, and diabetes.</div></div><div><h3>Conclusions</h3><div>Our findings do not support routine immediate CAG in non-ST-elevation myocardial infarction OHCA. A selective, delayed approach after hemodynamic stabilisation may improve survival. Clinicians should prioritise stabilisation before CAG, using pH, systolic blood pressure, and Glasgow Coma Scale as key prognostic indicators.</div></div>","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"35 1","pages":"Pages 104-115"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145632744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.hlc.2025.09.014
Macit Kalçik MD, Ömer Burak Çelik MD, Mucahit Yetim MD
{"title":"Letter to the Editor “Reconsidering the Roles of Computed Tomography Coronary Angiography and Stress Echocardiography in Acute Chest Pain”","authors":"Macit Kalçik MD, Ömer Burak Çelik MD, Mucahit Yetim MD","doi":"10.1016/j.hlc.2025.09.014","DOIUrl":"10.1016/j.hlc.2025.09.014","url":null,"abstract":"","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"35 1","pages":"Pages e9-e10"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145904219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.hlc.2025.12.012
C. Lac, H. Dimitri, J. Assad, J. Tan
{"title":"Corrigendum to: Abstract 290, Vol 34, Supplement 4, Page S289–S290 (2025) (Abstracts for the 73rd Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, 14–17 August 2025) entitled ‘Device-Detected Versus Questionnaire- Identified Obstructive Sleep Apnoea in Heart Failure Patients: A Comparative Study’","authors":"C. Lac, H. Dimitri, J. Assad, J. Tan","doi":"10.1016/j.hlc.2025.12.012","DOIUrl":"10.1016/j.hlc.2025.12.012","url":null,"abstract":"","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"35 1","pages":"Page e16"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145904225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.hlc.2025.05.102
Hisato Takagi MD, PhD
{"title":"True Lumen Mural Thrombus in Type B Aortic Dissection","authors":"Hisato Takagi MD, PhD","doi":"10.1016/j.hlc.2025.05.102","DOIUrl":"10.1016/j.hlc.2025.05.102","url":null,"abstract":"","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"35 1","pages":"Pages e1-e2"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145471037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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