Heart, Lung and Circulation最新文献

{"title":"Risk of Readmission After Acute Myocardial Infarction: Insights From the CADOSA Registry","authors":"Clementine Labrosciano PhD ,&nbsp;John A. Spertus MD, MPH ,&nbsp;Jing Wu PhD ,&nbsp;Christopher J. Zeitz MBBS, PhD ,&nbsp;Rosanna Tavella PhD ,&nbsp;Matthew I. Worthley MBBS, PhD ,&nbsp;Margaret Arstall MBBS, PhD ,&nbsp;Ajay Sinhal MD ,&nbsp;John F. Beltrame BMBS, PhD","doi":"10.1016/j.hlc.2025.06.1024","DOIUrl":"10.1016/j.hlc.2025.06.1024","url":null,"abstract":"<div><h3>Background</h3><div>Early identification of the one in five patients readmitted within 30 days of an acute myocardial infarction (AMI) hospitalisation provides an opportunity for targeted proactive intervention thereby reducing the risk of readmission. To target such an intervention to those most likely to benefit, this study sought to develop and validate a model predicting 30-day, all-cause, unplanned readmission after hospitalisation for AMI.</div></div><div><h3>Methods</h3><div>The index AMI encounter for patients undergoing acute coronary angiography between 2012 and 2022 enrolled into the CADOSA (Coronary Angiogram Database of South Australia) Registry and discharged home across four tertiary hospitals were included. A random split sample of 70% and 30% was used for the derivation and validation cohorts, respectively. Logistic regression with combination elimination was performed to develop the parsimonious clinical model within the derivation cohort and model discrimination was assessed in the validation cohort.</div></div><div><h3>Results</h3><div>Among 13,289 unique patients (mean age 64±13 years, 71% male, 41% ST-elevation AMIs), 14.2% were readmitted within 30 days. Readmitted patients were older (67±14 vs 63±13; p&lt;0.001) and less likely to present with a ST-elevation AMI (38% vs 42%; p=0.003). Predictors showing a higher likelihood of readmission were patients with abnormal estimated glomerular filtration rate, cardiogenic shock and increased heart rate upon arrival, new diagnosis of heart failure, being older and female, and a history of depression. The model had consistent moderate discrimination (C statistic=0.63 in the derivation and validation cohorts).</div></div><div><h3>Conclusions</h3><div>An Australian model for 30-day all-cause unplanned readmission has a similar performance to United States models. Further emphasis should be placed on providing additional support to high-risk patients upon arrival to the hospital to assist in reducing readmissions.</div></div>","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"34 12","pages":"Pages 1379-1388"},"PeriodicalIF":2.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145075250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementing Evidence to Inform Recovery After Cardiac Surgery via Median Sternotomy Is Feasible and Effective Using a Research Translation Framework","authors":"Samara Phillips BPhysio, MPH ,&nbsp;Julie Adsett BPhty, PhD ,&nbsp;Alison Mahoney BPhty ,&nbsp;Doa El-Ansary BAppSc(Phty), PhD","doi":"10.1016/j.hlc.2025.06.008","DOIUrl":"10.1016/j.hlc.2025.06.008","url":null,"abstract":"<div><h3>Background</h3><div>After cardiac surgery including median sternotomy, patients are often advised to restrict upper limb activity, lifting, and weight bearing to reduce the risk of wound dehiscence and sternal instability. “Keep Your Move in the Tube” (KMIT) is an evidence-based strategy developed for patients after a sternotomy for cardiac surgery that promotes early resumption of functional activities using biomechanical principles. To date, there is inconsistency of KMIT implementation to improve patient recovery and outcomes. The application of a knowledge translation approach may facilitate the transformation in practice required.</div><div>The aims of this study were to conduct a review of current practice, with a focus on exercise for patients after median sternotomy in public acute surgical and cardiac rehabilitation programs in Australia and assess the implementation of KMIT using the Knowledge to Action framework.</div></div><div><h3>Method</h3><div>This prospective, longitudinal, observational study used a RE-AIM framework for assessment. The project was undertaken in four main phases; i) a survey to assess cardiac rehabilitation practice, ii) development and codesign of an implementation strategy to standardise education and exercise training, iii) implementation, and iv) assessment of the implementation strategy between December 2021 and June 2024.</div></div><div><h3>Results</h3><div>The survey found lifting and weight bearing advice and exercise provided to patients after a sternotomy for cardiac surgery was inconsistent across the included cardiac rehabilitation programs. The results of the education delivered by 12 local change champions and attended by 390 clinicians demonstrated an improvement in KMIT familiarity from 11% to 76%. A total of 82% reported integrating KMIT principles into usual clinical practice, an increase from 23% at baseline. At follow-up, 82% of respondents reported that KMIT was embedded as clinical practice. Despite a comprehensive education and training strategy, a systematic implementation using a structured framework and high levels of adoption, uncertainty remained about load and time restrictions after a sternotomy, highlighting a need for strategies which focus on the key principles of KMIT and their implications for functional tasks and exercise.</div></div><div><h3>Conclusions</h3><div>Using a structured process to codesign, develop, and implement a bespoke education and training intervention, KMIT was successfully adopted across cardiac rehabilitation programs within a large health service. This study has also identified opportunities for future improvements and strategies to promote consistency translation and sustainability.</div></div>","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"34 12","pages":"Pages 1470-1477"},"PeriodicalIF":2.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145292065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Surgery Versus Conventional Treatment for Asymptomatic Severe Aortic Regurgitation: A Systematic Review and Meta-Analysis","authors":"Edson Gary Moreira Moreira MD, MSc,&nbsp;Attila Santos Berriel MD,&nbsp;Giovanna Paula Macedo De Lacerda Guedes MD,&nbsp;Melina Moroz Bärg MD,&nbsp;Marcela Dalla Bernardina Sena MD,&nbsp;Daniel Chagas Dantas MD,&nbsp;Mário Issa MD, PhD,&nbsp;Renato Tambellini Arnoni MD, PhD","doi":"10.1016/j.hlc.2025.05.086","DOIUrl":"10.1016/j.hlc.2025.05.086","url":null,"abstract":"<div><h3>Background</h3><div>The management of patients with severe asymptomatic aortic regurgitation remains controversial. This systematic review and meta-analysis aimed to assess and compare long-term outcomes between early surgery and conventional treatment (CT) for severe asymptomatic aortic regurgitation in patients with preserved left ventricular systolic function.</div></div><div><h3>Method</h3><div>We conducted a systematic search in the EMBASE, PubMed, and Cochrane databases for studies comparing early surgery with CT. The analysed outcome was death from all causes. We evaluated the risk of bias in the included studies using the ROBINS-I (Risk Of Bias In Non-randomised Studies of Interventions) tool.</div></div><div><h3>Results</h3><div>Three studies, involving 469 patients, were included. Of the participants studied, 57% underwent early surgery, and 43% underwent CT. Early surgery did significantly reduce all-cause mortality (odds ratio 0.35; 95% confidence interval 0.12–1.00; p=0.05; I²=54%).</div></div><div><h3>Conclusions</h3><div>Our study provides evidence supporting the idea that early surgery, in comparison to conservative management, is associated with better long-term outcomes in patients with severe asymptomatic aortic regurgitation and normal ventricular function.</div></div>","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"34 12","pages":"Pages 1373-1378"},"PeriodicalIF":2.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145354639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Whole-Body Impedance Cardiography-Derived Haemodynamic Parameters Associated With Outcomes in Clinically Stable Heart Failure Patients With Reduced Ejection Fraction","authors":"Emelissa J. Valcourt MD ,&nbsp;Olivia Pieroni MD ,&nbsp;Karen E. Alvarez BSc ,&nbsp;Mohammad Zahurul Islam MSc ,&nbsp;Hilary Bews MD ,&nbsp;Aleksander Dokollari MD ,&nbsp;Anita Soni MD ,&nbsp;Shelley Zieroth MD ,&nbsp;Ashish H. Shah MD, MD-Research","doi":"10.1016/j.hlc.2025.05.088","DOIUrl":"10.1016/j.hlc.2025.05.088","url":null,"abstract":"<div><h3>Background</h3><div>Heart failure with reduced ejection fraction (HFrEF) is one of the most prevalent chronic cardiac conditions. Despite recent advances, overall morbidity and mortality remain high. Routine outpatient evaluation is predominantly based on subjective descriptions of symptoms. The utility of non-invasively obtained haemodynamic parameters in identifying high-risk patients with HFrEF has not been described.</div></div><div><h3>Methods</h3><div>Clinically stable (&gt;3 months) patients with HFrEF from the tertiary HF clinic at St. Boniface Hospital, Canada were recruited. Resting and exercise-augmented (25 watts, up to 12 minutes on a mounted bike) haemodynamic parameters were obtained using a Non-Invasive Cardiac System (NICaS), a whole-body impedance cardiography-based technology. Electronic patient records were reviewed to identify outcomes.</div></div><div><h3>Results</h3><div>Overall, 63 patients (63.4±15.4 years; 11 [17.5%] female, mean body mass index 31.0±7.1 kg/m²) were recruited. Resting stroke index (SI) correlated with post-exercise SI (r=0.56). At 12-month follow-up, 25 of 63 subjects (39.7%) experienced adverse outcomes (emergency department presentation or unplanned HF hospitalisation, new-onset arrhythmia, referral for cardiac implantable electronic device implantation/optimisation, referral for palliative care and all-cause death). Lower resting SI, either supine (35.5±9.5 vs 40.3±8.0 mL/m²; p=0.02) or sitting (32.1±7.9 vs 37.6±7.9 mL/m²; p=0.009) and exaggerated exercise-augmented Granov–Goor index, a surrogate marker of impaired left ventricular contractility, were the hemodynamic parameters most strongly associated with outcomes.</div></div><div><h3>Conclusions</h3><div>Non-invasively obtained resting SI and higher exercise-augmented Granov–Goor index identify a high-risk cohort among patients with clinically stable HFrEF. Such findings should be validated in a larger prospective study.</div></div>","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"34 12","pages":"Pages 1430-1438"},"PeriodicalIF":2.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145426489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guideline-Based Lipid Lowering Therapy in a Rural and Remote High-Risk Population Presenting With a Second Acute Coronary Syndrome: Still a Way to Go","authors":"Thomas Barlow FRACP ,&nbsp;Ruth Arnold FRACP ,&nbsp;Harry C. Lowe FRACP, PhD","doi":"10.1016/j.hlc.2025.08.033","DOIUrl":"10.1016/j.hlc.2025.08.033","url":null,"abstract":"","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"34 12","pages":"Pages e174-e175"},"PeriodicalIF":2.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145658572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medium-Term Outcomes of Perceval Sutureless Aortic Valve Replacement in Aotearoa New Zealand","authors":"Navneet Singh MBChB, MSc(Dist), PGCertClinUlt ,&nbsp;Hannah Kim MBChB ,&nbsp;Parma Nand FRACS","doi":"10.1016/j.hlc.2025.06.005","DOIUrl":"10.1016/j.hlc.2025.06.005","url":null,"abstract":"<div><h3>Background</h3><div>The Perceval bioprosthesis is a contemporary sutureless technology utilised for surgical aortic valve replacement (AVR). Perceval valves allow for AVR with reduced cross-clamp and cardiopulmonary bypass times, which correlates with improved postoperative patient morbidity and mortality. However, there is a paucity of literature reporting the medium-term outcomes from Perceval AVR in New Zealand. We aimed to investigate the mid-term outcomes from Perceval AVR at our single centre.</div></div><div><h3>Method</h3><div>All consecutive patients undergoing Perceval AVR (during isolated or combined procedures) at our unit from March 2011 to August 2021 were retrospectively analysed from a prospectively-collected database.</div></div><div><h3>Results</h3><div>Across the 10-year study period, 145 patients (mean age: 73.2 years; males: 71.7%; mean EuroSCORE II: 3.78%) underwent Perceval AVR. The most common indication for surgery was aortic stenosis (82.5%). The operative caseload was complex, with only 27.6% of patients undergoing first-time isolated AVR. The mean crossclamp and cardiopulmonary bypass times were 74.7±40.6 and 111.3±63.6 minutes respectively. Latest follow-up transthoracic echocardiography (performed at a mean of 2.2±1.7 years postoperatively) revealed that 96% of patients had either none or only trivial paravalvular/transvalvular leaks. The 30-day mortality and stroke rates were 6.2% and 2.1% respectively. Medium-term survival rates across 5-year and 9.5-year follow-up were 70% and 55% respectively. There was only one reoperation on the aortic valve.</div></div><div><h3>Conclusions</h3><div>Across an older patient population undergoing complex cardiac surgery, Perceval AVR facilitates acceptable short-term and medium-term outcomes in terms of both prosthetic valvular function and survival.</div></div>","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"34 12","pages":"Pages 1464-1469"},"PeriodicalIF":2.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145174562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modernising Acute PE and VTE Management: Meta-Analysis of Newer Anticoagulants Versus Traditional Therapy on Recurrence and Mortality","authors":"Udvass Kumar Kotokey MBBS, DTCD, DNB ,&nbsp;Savitri Kumari MSc","doi":"10.1016/j.hlc.2025.05.092","DOIUrl":"10.1016/j.hlc.2025.05.092","url":null,"abstract":"<div><h3>Background</h3><div>Venous thromboembolism (VTE), encompassing deep vein thrombosis and pulmonary embolism (PE), is a leading cause of cardiovascular morbidity and mortality. While vitamin K antagonists (VKAs) and low molecular weight heparins (LMWHs) have long served as the standard of care, non-vitamin K antagonist oral anticoagulants, particularly factor Xa inhibitors, have emerged as promising alternatives due to their favourable pharmacokinetic profiles and ease of use. This meta-analysis aimed to evaluate the efficacy and safety of factor Xa inhibitors (apixaban, rivaroxaban, and edoxaban) compared with VKAs or LMWHs in treating acute VTE and PE, including recurrence prevention and mortality outcomes.</div></div><div><h3>Method</h3><div>A systematic review and meta-analysis were conducted in accordance with PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses) 2020 guidelines. Seven randomised controlled trials comprising 25,510 patients were included. Outcomes assessed included VTE recurrence, PE recurrence, and all-cause mortality. Subgroup analyses examined effects in cancer and non-cancer-associated VTE, VTE in renal impairment, VTE-related mortality, bleeding-related mortality, and major bleeding in cancer, non-cancer, and solid tumours. Statistical analyses were performed using a random-effects model.</div></div><div><h3>Results</h3><div>Factor Xa inhibitors were associated with a statistically significant 15% reduction in VTE recurrence (hazard ratio [HR] 0.85; 95% confidence interval [CI] 0.72–0.99; p=0.04). In cancer-associated VTE, they significantly reduced recurrence risk by 24% (HR 0.76; 95% CI 0.59–0.98). In patients without cancer, a non-significant 10% reduction was observed (HR 0.90; 95% CI 0.76–1.06). Major bleeding was significantly lower in patients without cancer (HR 0.76; 95% CI 0.58–0.99), while no significant difference was noted in cancer-associated VTE or solid tumour subgroups. Factor Xa inhibitors significantly reduced bleeding-related mortality by 49% (HR 0.51; 95% CI 0.26–0.99), but showed no difference in VTE-specific or all-cause mortality.</div></div><div><h3>Conclusions</h3><div>Factor Xa inhibitors are effective and safe alternatives to traditional anticoagulants for most patients with acute VTE. They significantly reduce VTE recurrence, particularly in patients with cancer and bleeding-related mortality. Major bleeding was significantly less in the non-cancer subgroup. These findings support their use as first-line therapy in appropriately selected patients, with consideration of individual bleeding risk, cancer type, renal function, and treatment setting.</div></div>","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"34 12","pages":"Pages 1319-1331"},"PeriodicalIF":2.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145476949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanical Thrombectomy Reduces Increased High Sensitivity Troponin Levels in Intermediate-High Risk Pulmonary Embolism.","authors":"Richard Schell, Felix Alban, Norbert Frey, Christian Erbel","doi":"10.1016/j.hlc.2025.08.023","DOIUrl":"https://doi.org/10.1016/j.hlc.2025.08.023","url":null,"abstract":"<p><strong>Background: </strong>Pulmonary embolism is associated with significant mortality and remarkably often subject to misdiagnosis, which further adversely affects prognosis. Disease severity and corresponding prognosis are strongly dependent on the risk constellation and determine the therapy. Therefore, we sought to analyse how mechanical thrombectomy influences short term clinical, laboratory, and haemodynamic findings in patients with symptomatic pulmonary artery embolism.</p><p><strong>Method: </strong>In this study, we retrospectively analysed clinical, laboratory, and haemodynamic parameters in 32 patients with symptomatic pulmonary embolism who underwent mechanical thrombectomy using the FlowTriever device. Only patients with pulmonary embolism confirmed by computed tomography pulmonary angiography and classified as intermediate-high or high risk according to the current European Society of Cardiology guidelines were included. The main outcome measures were periprocedural changes in troponin, lactate, pulmonary artery pressures, and vital signs.</p><p><strong>Results: </strong>Reductions of increased heart rate, pulmonary arterial pressure, and right ventricle-to-left ventricle ratio were observed immediately after the procedure and in early clinical follow-up, as well as improvement in arterial oxygen saturation and demand. Interventional thrombectomy further resulted in a reduction of increased levels of high-sensitivity troponin and lactate. In summary, the analysis of this study shows consistent respiratory and haemodynamic improvements in line with other published data on mechanical thrombectomy with this device.</p><p><strong>Conclusions: </strong>Mechanical thrombectomy in patients with pulmonary artery embolism at intermediate-high risk was associated with an immediate and significant decrease in both specific myocardial and systemic biomarkers, for which prognostic relevance has been repeatedly demonstrated.</p>","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145648361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Securing Long-Term Heart Health for Australians: Understanding How Funding Structures in Cardiac Rehabilitation Influence Cardiovascular Inequities.","authors":"Sarah Gauci, Lan Gao, Robyn Gallagher, Julie Redfern, Susie Cartledge, Adrienne O'Neil","doi":"10.1016/j.hlc.2025.07.016","DOIUrl":"https://doi.org/10.1016/j.hlc.2025.07.016","url":null,"abstract":"","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145451780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Pursuit of Truth: Revisiting Causation Versus Association in Contemporary Cardiovascular Research","authors":"Jonathan L. Ciofani BMedSc, MPH, MD ,&nbsp;Usaid K. Allahwala MBBS, PhD, FRACP, FCSANZ ,&nbsp;Avedis Ekmejian MBBS, MSc, PhD, FRACP, FCSANZ ,&nbsp;Salvatore Pepe PhD, FAHA, FESC, FCSANZ ,&nbsp;Ravinay Bhindi MBBS, PhD, FRACP, FCSANZ","doi":"10.1016/j.hlc.2025.10.005","DOIUrl":"10.1016/j.hlc.2025.10.005","url":null,"abstract":"","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"34 11","pages":"Pages 1150-1155"},"PeriodicalIF":2.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145478819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}